Tokushima University / Educator and Researcher Directory --- Kato, Ryo

Search:

Tokushima University ⟩ Institute of Post-LED Photonics ⟩
Tokushima University ⟩ Research Clusters ⟩ Research Clusters ⟩ 2201001 シームレスな光イノベーションを創出する次世代光技術 ⟩
Tokushima University ⟩ Research Clusters ⟩ Research Clusters ⟩ 2202006 接着歯学&光工学との最先端融合によるSuper Tooth創生 ∼次世代の低侵襲接着再生歯科治療への展開∼ ⟩

(Files for researchmap) [PDF manual] [Auto-propagate to researchmap]

Research

Personal Web Page

https://orcid.org/0000-0002-9134-1382 (ORCID)

Field of Study

Subject of Study

Book / Paper

Academic Paper (Judged Full Paper):

1.	Ryo Kato, Taka-aki Yano and Takuo Tanaka : Single-cell infrared vibrational analysis by optical trapping mid-infrared photothermal microscopy, Analyst, Vol.148, No.6, 1285-1290, 2023. (Summary) Single-cell analysis by means of vibrational spectroscopy combined with optical trapping is a reliable platform for unveiling cell-to-cell heterogeneities in vast populations. Although infrared (IR) vibrational spectroscopy provides rich molecular fingerprint information on biological samples in a label-free manner, its application with optical trapping has never been achieved due to weak gradient forces generated by the diffraction-limited focused IR beam and strong background of water absorption. Herein, we present single-cell IR vibrational analysis that incorporates mid-infrared photothermal (MIP) microscopy with optical trapping. Optically trapped single polymer particles and red blood cells (RBCs) in blood could be chemically identified owing to their IR vibrational fingerprints. This single-cell IR vibrational analysis further allowed us to probe the chemical heterogeneities of RBCs originating from the variation in the intracellular characteristics. Our demonstration paves the way for the IR vibrational analysis of single cells and chemical characterization in various fields. (Keyword) Microscopy / Optical Tweezers / Spectrophotometry, Infrared / Polymers / Single-Cell Analysis (Link to Publication Site) ● Publication site (DOI): 10.1039/D2AN01917E (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 36811918 ● Search Scopus @ Elsevier (PMID): 36811918 ● Search Scopus @ Elsevier (DOI): 10.1039/D2AN01917E (DOI: 10.1039/D2AN01917E, PubMed: 36811918)
2.	Ryo Kato, Taka-aki Yano, Takeo Minamikawa and Takuo Tanaka : High-sensitivity hyperspectral vibrational imaging of heart tissues by mid-infrared photothermal microscopy, Analytical Sciences, Vol.38, No.12, 1497-1503, 2022. (Summary) Visualizing the spatial distribution of chemical compositions in biological tissues is of great importance to study fundamental biological processes and origin of diseases. Raman microscopy, one of the label-free vibrational imaging techniques, has been employed for chemical characterization of tissues. However, the low sensitivity of Raman spectroscopy often requires a long acquisition time of Raman measurement or a high laser power, or both, which prevents one from investigating large-area tissues in a nondestructive manner. In this work, we demonstrated chemical imaging of heart tissues using mid-infrared photothermal (MIP) microscopy that simultaneously achieves the high sensitivity benefited from IR absorption of molecules and the high spatial resolution down to a few micrometers. We successfully visualized the distributions of different biomolecules, including proteins, phosphate-including proteins, and lipids/carbohydrates/amino acids. Further, we experimentally compared MIP microscopy with Raman microscopy to evaluate the sensitivity and photodamage to tissues. We proved that MIP microscopy is a highly sensitive technique for obtaining vibrational information of molecules in a broad fingerprint region, thereby it could be employed for biological and diagnostic applications, such as live-tissue imaging. (Keyword) Microscopy / Spectrum Analysis, Raman / Vibration / Proteins / Lasers (Link to Publication Site) ● Publication site (DOI): 10.1007/s44211-022-00182-8 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 36070070 ● Search Scopus @ Elsevier (PMID): 36070070 ● Search Scopus @ Elsevier (DOI): 10.1007/s44211-022-00182-8 (DOI: 10.1007/s44211-022-00182-8, PubMed: 36070070)
3.	Ryo Kato, Toki Moriyama, Takayuki Umakoshi, Taka-aki Yano and Prabhat Verma : Ultrastable tip-enhanced hyperspectral optical nano-imaging for defect analysis of large-sized WS2 layers, Science Advances, Vol.8, No.28, 2022. (Tokushima University Institutional Repository) ● Metadata: 117851 (Link to Publication Site) ● Publication site (DOI): 10.1126/sciadv.abo4021 (Link to Search Site for Scientific Articles) ● Summary page in Scopus @ Elsevier: 2-s2.0-85134651863 (Tokushima University Institutional Repository: 117851, DOI: 10.1126/sciadv.abo4021, Elsevier: Scopus)
4.	Ryo Kato, Mitsuhiro Uesugi, Yoshie Komatsu, Fusatoshi Okamoto, Takuo Tanaka, fumihisa Kitawaki and Taka-aki Yano : Highly Stable Polymer Coating on Silver Nanoparticles for Efficient Plasmonic Enhancement of Fluorescence, ACS Omega, 4286-4292, 2022. (Tokushima University Institutional Repository) ● Metadata: 117207 (Link to Publication Site) ● Publication site (DOI): 10.1021/acsomega.1c06010 (Link to Search Site for Scientific Articles) ● Summary page in Scopus @ Elsevier: 2-s2.0-85124952347 (Tokushima University Institutional Repository: 117207, DOI: 10.1021/acsomega.1c06010, Elsevier: Scopus)
5.	Ryo Kato, Taka-aki Yano and Takuo Tanaka : Multi-modal vibrational analysis of blend polymers using mid-infrared photothermal and Raman microscopies, Vibrational Spectroscopy, Vol.118, No.1, 2022. (Link to Publication Site) ● Publication site (DOI): 10.1016/j.vibspec.2021.103333 (Link to Search Site for Scientific Articles) ● Summary page in Scopus @ Elsevier: 2-s2.0-85123212071 (DOI: 10.1016/j.vibspec.2021.103333, Elsevier: Scopus)
6.	Takuo Tanaka, Taka-aki Yano and Ryo Kato : Nanostructure-enhanced infrared spectroscopy, Nanophotonics, Vol.11, No.11, 2541-2561, 2021. (Tokushima University Institutional Repository) ● Metadata: 117245 (Link to Publication Site) ● Publication site (DOI): 10.1515/nanoph-2021-0661 (Link to Search Site for Scientific Articles) ● Summary page in Scopus @ Elsevier: 2-s2.0-85120993492 (Tokushima University Institutional Repository: 117245, DOI: 10.1515/nanoph-2021-0661, Elsevier: Scopus)

Proceeding of International Conference:

1.	Taka-aki Yano and Ryo Kato : All-dielectric metamaterial reflectors for highly-sensitive infrared spectroscopy, A3 Metamaterials Forum, Seoul,Korea, Jun. 2022.
2.	Taka-aki Yano, Ryo Kato and Takuo Tanaka : Active plasmonic vibrational spectroscopy of single-molecular chemical reactions, SPIE Optics + Photonics 2022, San Diego, Jun. 2022.
3.	Akari Okimura, Ryo Kato, Taka-aki Yano and Takuo Tanaka : Tip-enhanced Raman analysis of inorganic-binding peptide molecules, SPIE Photonics West 2022 On Demand, Feb. 2022. (Link to Publication Site) ● Publication site (DOI): 10.1117/12.2608429 (Link to Search Site for Scientific Articles) ● Search Scopus @ Elsevier (DOI): 10.1117/12.2608429 (DOI: 10.1117/12.2608429)
4.	Ryo Kato, Taka-aki Yano and Takuo Tanaka : Multimodal vibrational imaging based on mid-infrared photothermal microscopy, SPIE Photonics West 2022 On Demand, Online, Feb. 2022.
5.	Taichi Hara, Ryo Kato, Taka-aki Yano and Takuo Tanaka : Metasurface-based perfect reflectors for highly-sensitive infrared spectroscopy, SPIE Photonics West 2022 On Demand, Feb. 2022.
6.	Mitsuhiro Uesugi, Yoshie Komatsu, Fusatoshi Okamoto, Ryo Kato, Takuo Tanaka, Taka-aki Yano and Fumihisa Kitawaki : Highly-stable Polymer Coating on Metallic Nanoparticles for Plasmonic Fluorescence Enhancement, The 9th International Symposium on Surface Science (ISSS-9), Dec. 2021.

Proceeding of Domestic Conference:

1.	Ryo Kato : バイオ・メディカル応用に向けたプラズモニック超解像ラマン顕微鏡の開発, 第47回レーザ顕微鏡研究会&シンポジウム, Nov. 2022.
2.	Masayuki Fujiwara, 宮坂禎也, 小野雅之, Ryo Kato, Takuo Tanaka, 齋藤敦, 長谷川祐一, 糸長誠 and Taka-aki Yano : プラズモニック構造を用いたデジタル分光バイオセンシング, 医用分光学研究会第20回年会, Oct. 2022.
3.	Masayuki Fujiwara, 宮坂禎也, 小野雅之, Ryo Kato, Taira Kajisa, Takeshi Yasui, Takuo Tanaka, 齋藤敦, 長谷川祐一, 糸長誠 and Taka-aki Yano : 金ナノ粒子-金ナノホール型ハイブリッド構造のプラズモン共鳴特性とデジタル比色センシング応用, 第83回応用物理学会秋季学術講演会, 23a-A101-4, Sep. 2022.
4.	沖村あかり, Ryo Kato, Taka-aki Yano and Takuo Tanaka : 無機材料認識ペプチド分子のギャップモード探針増強ラマン分光, 第69回応用物理学会春季学術講演会, Mar. 2022.
5.	原太一, Ryo Kato, Taka-aki Yano and Takuo Tanaka : 中赤外誘電体メタマテリアルの開発と高感度赤外分光への応用, 第69回応用物理学会春季学術講演会, Mar. 2022.
6.	沖村あかり, Ryo Kato, Taka-aki Yano and Takuo Tanaka : ギャップモード探針増強ラマン分光法を用いた無機材料認識ペプチドの単一分子分光ギャップモード探針増強ラマン分光法を用いた無機材料認識ペプチドの単一分子分光, 2021年度日本分光学会年次講演会, Oct. 2021.
7.	原太一, Ryo Kato, Taka-aki Yano and Takuo Tanaka : 中赤外誘電体メタマテリアルの開発と高感度赤外分光への応用, 2021年度日本分光学会年次講演会, Oct. 2021.
8.	Taichi Hara, Ryo Kato, Taka-aki Yano and Takuo Tanaka : Perfect dielectric-metamaterial reflectors for highly-sensitive infrared spectroscopy, Optics and Photonics Japan 2021, Oct. 2021.
9.	Akari Okimura, Ryo Kato, Taka-aki Yano and Takuo Tanaka : Tip-enhanced Raman spectroscopy of single biomolecule, Optics and Photonics Japan 2021, Oct. 2021.
10.	小松由枝, 上杉充弘, 岡本房俊, Ryo Kato, Takuo Tanaka, Taka-aki Yano and 北脇文久 : 金属ナノ粒子の安定的高分子被膜とプラズモン蛍光増強センサーへの応用, 日本分析化学会第70年会, Sep. 2021.

Grants-in-Aid for Scientific Research (KAKEN Grants Database @ NII.ac.jp)

中赤外光熱変調散乱計測による生体化学イメージング (Project/Area Number: 23H04139 )
探針増強ラマン散乱・赤外吸収計測による生体ダイナミクスの解明 (Project/Area Number: 22K14650 )
Super-resolution Raman and IR hybrid vibrational spectroscopy (Project/Area Number: 21K20503 )
Search by Researcher Number (90910513)