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Tokushima UniversityInstitute of Advanced Medical Sciences基幹研究部門 (Files for researchmap) [PDF manual] [Auto-propagate to researchmap]

Research

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Field of Study

Life sciences [Biophysics]
Life sciences [Structural biochemistry]

Subject of Study

Book / Paper

Academic Paper (Judged Full Paper):

1. Yoshikazu Hattori, Munehiro Kumashiro, Hiroyuki Kumeta, Taisei Kyo, Soichiro Kawagoe, Motonori Matsusaki and Tomohide Saio :
A Disease-Associated Mutation Impedes PPIA through Allosteric Dynamics Modulation,
Biochemistry, 64, 14, 2971-2975, 2025.
(DOI: 10.1021/acs.biochem.5c00260,   Elsevier: Scopus)
2. Soichiro Kawagoe, Motonori Matsusaki, Takuya Mabuchi, Yuto Ogasawara, Kazunori Watanabe, Koichiro Ishimori and Tomohide Saio :
Mechanistic Insights Into Oxidative Response of Heat Shock Factor 1 Condensates,
JACS Au, 5, 2, 606-617, 2025.
(DOI: 10.1021/jacsau.4c00578,   Elsevier: Scopus)
3. Saori Yoshimura, Ryuki Shimada, Koji Kikuchi, Soichiro Kawagoe, Hironori Abe, Sakie Iisaka, Sayoko Fujimura, Kei-Ichiro Yasunaga, Shingo Usuki, Naoki Tani, Takashi Ohba, Eiji Kondoh, Tomohide Saio, Kimi Araki and Kei-Ichiro Ishiguro :
Atypical heat shock transcription factor HSF5 is critical for male meiotic prophase under non-stress conditions.,
Nature Communications, 15, 1, 3330, 2024.
(Tokushima University Institutional Repository: 2012857,   DOI: 10.1038/s41467-024-47601-0,   PubMed: 38684656)
4. Soichiro Kawagoe, Munehiro Kumashiro, Takuya Mabuchi, Hiroyuki Kumeta, Koichiro Ishimori and Tomohide Saio :
Heat-Induced Conformational Transition Mechanism of Heat Shock Factor 1 Investigated by Tryptophan Probe.,
Biochemistry, 61, 24, 2897-2908, 2022.
(DOI: 10.1021/acs.biochem.2c00492,   PubMed: 36485006)
5. Shuhei Yoshida, Shota Uehara, Noriyasu Kondo, Yu Takahashi, Shiho Yamamoto, Atsushi Kameda, Soichiro Kawagoe, Naoko Inoue, Masami Yamada, Norito Yoshimura and Yuki Tachibana :
Peptide-to-Small Molecule: A Pharmacophore-Guided Small Molecule Lead Generation Strategy from High-Affinity Macrocyclic Peptides.,
Journal of Medicinal Chemistry, 65, 15, 10655-10673, 2022.
(DOI: 10.1021/acs.jmedchem.2c00919,   PubMed: 35904556)
6. Soichiro Kawagoe, Hiroshi Nakagawa, Hiroyuki Kumeta, Koichiro Ishimori and Tomohide Saio :
Structural insight into proline cis/ trans isomerization of unfolded proteins catalyzed by the trigger factor chaperone,
The Journal of Biological Chemistry, 293, 39, 15095-15106, 2018.
(DOI: 10.1074/jbc.RA118.003579,   PubMed: 30093407)
7. Tomohide Saio, Soichiro Kawagoe, Koichiro Ishimori and G Charalampos Kalodimos :
Oligomerization of a molecular chaperone modulates its activity.,
eLife, 7, e35731, 2018.
(DOI: 10.7554/eLife.35731,   PubMed: 29714686,   Elsevier: Scopus)

Review, Commentary:

1. Soichiro Kawagoe, Koichiro Ishimori and Tomohide Saio :
Structural and Kinetic Views of Molecular Chaperones in Multidomain Protein Folding.,
International Journal of Molecular Sciences, 23, 5, Feb. 2022.
(Tokushima University Institutional Repository: 2011035,   DOI: 10.3390/ijms23052485,   PubMed: 35269628,   Elsevier: Scopus)
2. Soichiro Kawagoe, Mori Eiichiro and Tomohide Saio :
Regulation of Liquid-Liquid Phase Separation by Molecular Chaperones,
Thermal Medicine, 37, 2, 31-44, Aug. 2021.
(DOI: 10.3191/thermalmed.37.31,   CiNii: 1390570408616681984)

Proceeding of International Conference:

1. Soichiro Kawagoe, Kumeta Hiroyuki and Tomohide Saio :
Flipping of the tryptophan ring in the protein core probed by 19F NMR-based solvent accessibility profiling,
2025 Korea-Japan Joint Conference on Protein Science, Jun. 2025.
2. Soichiro Kawagoe and Tomohide Saio :
Structural dynamics regulating the molecular assembly of heat shock transcription factor 1,
International Symposium on Multifaceted Protein Dynamics, Sep. 2024.
3. Soichiro Kawagoe, Kumeta Hiroyuki and Tomohide Saio :
Aromatic Ring Flipping in Structured Domain Modulates the Assembly of Intrinsically Disordered Region,
The 30th International Conference on Magnetic Resonance in Biological Systems, Aug. 2024.

Proceeding of Domestic Conference:

1. Soichiro Kawagoe, 久米田博之 (名) and Tomohide Saio :
DNA結合ドメインの構造ダイナミクスによる 転写因子Hsf1の液-液相分離制御,
第97回 日本生化学会大会, Nov. 2024.
2. Soichiro Kawagoe, 久米田博之 (名) and Tomohide Saio :
転写因子Hsf1の液-液相分離を制御する DNA結合ドメインの構造平衡メカニズム,
第63回 NMR討論会, Oct. 2024.
3. Soichiro Kawagoe :
溶液NMRを主体としたストレス応答性液-液相分離の分子機構解析,
第59回 先端酵素学研究所セミナー(最先端研究者特別講演会), Jul. 2024.
4. 武井 梓穂, 宇賀 神魁, Soichiro Kawagoe, Tomohide Saio, 松田 正, 前仲 勝実, 姚 閔 and 尾瀬 農之 :
乳がん特異的キナーゼとアダプター蛋白質が形成する分子集合と酵素活性の相関を検証する,
第24回日本蛋白質科学会年会, Jun. 2024.
5. Soichiro Kawagoe, 久米田 博之 and Tomohide Saio :
Heat shock factor-1のストレス応答性液-液相分離の構造基盤,
第24回日本蛋白質科学会年会, Jun. 2024.
6. Soichiro Kawagoe, 馬渕 拓哉, 久米田 博之, Motonori Matsusaki, 熊代 宗弘, 石森 浩一郎 and Tomohide Saio :
Molecular mechanisms of multiple interactions regulating stress sensor assembly,
第61回日本生物物理学会年会, Nov. 2023.
7. 朱 浩傑, Soichiro Kawagoe, 久米田 博之, 石森 浩一郎 and Tomohide Saio :
タンパク質アンフォールディングを担う シャペロン複合体の構造解析,
第 62回 NMR討論会, Nov. 2023.
8. Soichiro Kawagoe :
溶液NMR法による弱い相互作用の分子機構解析とキャリア形成,
第6回ExCELLS若手リトリート, Oct. 2023.
9. Soichiro Kawagoe :
ストレスセンサーの活性制御を担うプロミスカス相互作⽤の分⼦機構,
2023年度徳島⼤学先端酵素学研究所シンポジウム, Jul. 2023.
10. Soichiro Kawagoe, 馬渕 拓哉, 久米田 博之, 熊代 宗弘, 石森 浩一郎 and Tomohide Saio :
局所構造形成と連動したheat shock factor-1の会合状態変化,
第23回日本蛋白質科学会年会, Jul. 2023.
11. Soichiro Kawagoe, Motonori Matsusaki, 石森 浩一郎 and Tomohide Saio :
高次多量体形成が駆動するheat shock factor-1液滴の酸化的相転移,
第 22 回日本蛋白質科学会年会, Jun. 2022.

Grants-in-Aid for Scientific Research (KAKEN Grants Database @ NII.ac.jp)

  • Structural insight into the interaction network driving the multi-state transition of heat shock transcription factor 1 (Project/Area Number: 24K18063 )
  • Kinetic analysis of multivalent interaction regulating the dynamic molecular assembly (Project/Area Number: 23K19353 )
  • Mechanism of chaperone activity modulation through promiscuous recognitions (Project/Area Number: 23K23824 )
  • Search by Researcher Number (10980716)