Tokushima University / Educator and Researcher Directory --- Matsumura, Yuki

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Research

Personal Web Page

https://researchmap.jp/matsumura-yuki (researchmap)

Field of Study

○	口腔保健学
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Subject of Study

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○	口腔がんとFusobacterium nucleatumの関連性の解明，有機フッ素化合物が及ぼす口腔への影響

Book / Paper

(See https://researchmap.jp/matsumura-yuki (researchmap) for Published Book / Papers / Presentations.)

Academic Paper (Judged Full Paper):

1.	Yuki Matsumura, Daisuke Hinode, Makoto Fukui, Masami Yoshioka, Asakuma Hiroki and Takii Hiroshi : Effectiveness of an oral care tablet containing kiwifruit powder in reducing oral bacteria in tongue coating: A crossover trial, Clinical and Experimental Dental Research, 6, 2, 197-206, 2020. (Summary) The aim of this study was to investigate the effect of an oral care tablet containing kiwifruit powder on oral bacteria in tongue coating compared with tongue brushing. Thirty-two healthy, young adults were enrolled, and a crossover clinical trial was conducted. The volatile sulfur compound (VSC) concentration, Winkel tongue-coating index (WTCI), and the number of total bacteria in addition to Fusobacterium nucleatum in tongue coating were measured. We instructed subjects to remove tongue coating by tongue brush for Intervention I, to keep the oral care tablet containing kiwifruit powder on the tongue dorsum and to let it dissolve naturally for Intervention II, and three oral care tablets 1 day before the measurement for Intervention III. There were significant differences in terms of the level of H S, VSC, and WTCI at Intervention I and all evaluation values at Intervention II. There were significant differences in terms of the level of H S, VSC, WTCI, the number of total bacteria, and F. nucleatum at Intervention III. The value of WTCI, the number of bacteria, and F. nucleatum decreased significantly after taking the oral care tablets than after tongue brushing. When compared with Interventions I and III, Intervention III showed the effective results; there were significant differences in the number of total bacteria and F. nucleatum between tongue brushing and taking tablets. These results suggested that the oral care tablet containing kiwifruit powder could be effective in reducing total bacteria and F. nucleatum in tongue coating when compared with tongue brushing. (Tokushima University Institutional Repository) ● Metadata: 2008762 (Link to Publication Site) ● Publication site (DOI): 10.1002/cre2.262 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 32250572 ● Summary page in Scopus @ Elsevier: 2-s2.0-85076095991 (Tokushima University Institutional Repository: 2008762, DOI: 10.1002/cre2.262, PubMed: 32250572, Elsevier: Scopus)
2.	河野りか, 土井登紀子, Makoto Fukui, Yuki Matsumura, Harumi Sakamoto, 玉谷香奈子, 吉岡昌美, 福島襄, 阿部昭人 and Daisuke Hinode : 徳島県内2校の児童の肥満と食習慣を含む生活習慣との関連性, Journal of Shikoku Public Health Society, 65, 1, 87-91, 2020. (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1010005505836042368 (CiNii: 1010005505836042368)

Proceeding of International Conference:

1.	Yuki Matsumura, Yasuhiro Mouri, Chen Siqi, Yagi Sayaka, Kumiko Kamada, Kawabata Ren, Naito Kurio, Yasusei Kudo and Natsumi Fujiwara : Localized heterogeneity of oral cancer microbiota reveals Fusobacterium pathogenicity along the oralsystemic disease axis, International Symposium on Dental Hygiene(202679-11, Milan, Italy), Jul. 2026.
2.	Natsumi Fujiwara, Chen Siqi, Yasuhiro Mouri, Yuki Matsumura, Ryo Kanamura, Kumiko Kamada, Yoshiko Yamamura, YAGI Sayaka, Naito Kurio, Yoshiaki Kitamura and Yasusei Kudo : Diversity of Site-Specific Oral Microbiota in Oral Cancer, 2025 IADR/PER General Session (Barcelona, Spain, 6/25~6/28), Jun. 2025.
3.	Yuki Matsumura, Daisuke Hinode, Masami Yoshioka, Asakuma Hiroki and Takii Hiroshi : Effect of kiwifruit and blueberry extract against bacterial VSC production, 96th General session of the International Association for Dental Research, London, UK, Jul. 2018.

Proceeding of Domestic Conference:

1.	KAWABATA Ren, Yuki Matsumura, Chen Siqi, Yasusei Kudo and Natsumi Fujiwara : 口腔癌患者由来Fusobacterium nucleatumの付着因子発現と口腔癌細胞への付着に関する検討, 第 79 回日本細菌学会中国・四国支部総会 (徳島市), Oct. 2026.
2.	Natsumi Fujiwara, Yuki Matsumura, siqi chen, ren kawabata and Yasusei Kudo : Bacterial Driversity in Oral Cancer Tissues and Pathogenic Potentioal of Fusobacterium nucleatum, 第85回日本癌学会学術総会, Sep. 2026.
3.	Yuki Matsumura, 上西よつ葉, 矢木颯香 and Natsumi Fujiwara : 歯面滑沢感が及ぼす機械歯面清掃の患者満足度に関する研究, 日本歯科衛生学会第20回学術大会, Nov. 2025.
4.	Yuki Matsumura, Kumiko Kamada, Atsushi Uesugi, 山村佳子, Naito Kurio, Yasusei Kudo and Natsumi Fujiwara : 口腔がん局所における細菌叢とFusobacterium臨床分離株の病原性の検討, 第72回日本口腔科学会中国・四国地方部会, Oct. 2025.
5.	Natsumi Fujiwara, Yuki Matsumura, Kumiko Kamada, Yoshiko Yamamura, Naito Kurio and Yasusei Kudo : Oral Microbiota in oral cancer Lesions: Isolation and Pathogenicity of Clinical Fusobacterium Strains, 第79回日本口腔科学会学術集会, May 2025.
6.	Yuki Matsumura, Daisuke Hinode, Makoto Fukui, Harumi Sakamoto, 吉岡昌美, 朝熊弘樹 and 滝井寛 : 舌苔細菌に対する口中ケアタブレットの有効性に関するクロスオーバー試験, 徳島県歯科医学大会, Feb. 2020.
7.	河野りか, Tokiko Doi, Makoto Fukui, Yuki Matsumura, Harumi Sakamoto, Kanako Tamatani, Masami Yoshioka, 福島襄, 阿部昭人 and Daisuke Hinode : 児童の肥満と口腔状態および生活習慣の関連性, 第29回近畿・中国・四国口腔衛生学会, Sep. 2018.
8.	Yuki Matsumura, Daisuke Hinode, Tokiko Doi, Harumi Sakamoto, Rika Kawano, Masami Yoshioka, 滝井寛 and 朝熊弘樹 : 舌苔中の細菌および口臭に対する口中ケアタブレットの有効性の検討, 第67回口腔衛生学会・総会, May 2018.
9.	Natsumi Fujiwara, Kazumi Ozaki, Shizuko Yanagisawa, Mariko Seyama, Yuki Matsumura, Rika Kawano and Yasuhiko Shirayama : 徳島県那賀町における口腔ケア実施の実態調査と支援職員への口腔ケア研修会の取り組み, 第67回日本口腔衛生学会, 68, 165, May 2018.
10.	河野りか, Tokiko Doi, Yuki Matsumura, Daisuke Hinode, Masami Yoshioka, 中江弘美, 福島襄 and 阿部昭人 : 児童の食習慣と肥満との関連性, 第82回全国学校歯科保健研究大会, Oct. 2017.
11.	Yuki Matsumura, Daisuke Hinode, Yuka Sogawa, 山崎明香 and Masami Yoshioka : ブルーベリーのFusobacterium nucleatum発育抑制およびメチルメルカプタン産生抑制への関与, 第27回近畿・中国・四国口腔衛生学会総会, Oct. 2017.

Grants-in-Aid for Scientific Research (KAKEN Grants Database @ NII.ac.jp)

環境化学物質PFOAによる口腔発がんメカニズムの解明に関する基盤研究 (Project/Area Number: 26K12939 )
Elucidation of oral cancer microenvironment related to proliferation and aggregation of Fusobacterium nucleatum (Project/Area Number: 25K13167 )
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