Tokushima University / Educator and Researcher Directory --- Fujihara, Hideaki

Search:

Tokushima University ⟩ Graduate School of Technology, Industrial and Social Sciences ⟩ 社会総合科学域 ⟩ 人間科学系 ⟩ スポーツ健康分野 ⟩
Tokushima University ⟩ Faculty of Integrated Arts and Sciences ⟩ Department of Integrated Arts and Social Sciences ⟩ Health Sciences of Mind and Body ⟩

(Files for researchmap) [PDF manual] [Auto-propagate to researchmap]

Research

Personal Web Page

https://researchmap.jp/fujihara_hideaki (researchmap)

Field of Study

○	発達心理学，スポーツ心理学，運動疫学

Subject of Study

○	心身の健康と生活習慣の関連性 (developmental psychology, スポーツ心理学, 食事, 運動, 腸内細菌叢)

Book / Paper

(See https://researchmap.jp/fujihara_hideaki (researchmap) for Published Book / Papers / Presentations.)

Academic Paper (Judged Full Paper):

1.	Eriko Ueda, Michiko Matsunaga, Hideaki Fujihara, Takamasa Kajiwara, K Aya Takeda, Satoshi Watanabe, Keisuke Hagihara and Masako Myowa : Temperament in Early Childhood Is Associated With Gut Microbiota Composition and Diversity., Developmental Psychobiology, 66, 7, 2024. (Summary) Temperament is a key predictor of human mental health and cognitive and emotional development. Although human fear behavior is reportedly associated with gut microbiome in infancy, infant gut microbiota changes dramatically during the first 5 years, when the diversity and composition of gut microbiome are established. This period is crucial for the development of the prefrontal cortex, which is involved in emotion regulation. Therefore, this study investigated the relationship between temperament and gut microbiota in 284 preschool children aged 3-4 years. Child temperament was assessed by maternal reports of the Children's Behavior Questionnaire. Gut microbiota (alpha/beta diversity and genera abundance) was evaluated using 16S rRNA sequencing of stool samples. A low abundance of anti-inflammatory bacteria (e.g., Faecalibacterium) and a high abundance of pro-inflammatory bacteria (e.g., Eggerthella, Flavonifractor) were associated with higher negative emotionality and stress response (i.e., negative affectivity, β = -0.17, p = 0.004) and lower positive emotionality and reward-seeking (i.e., surgency/extraversion, β = 0.15, p = 0.013). Additionally, gut microbiota diversity was associated with speed of response initiation (i.e., impulsivity, a specific aspect of surgency/extraversion, β = 0.16, p = 0.008). This study provides insight into the biological mechanisms of temperament and takes important steps toward identifying predictive markers of psychological/emotional risk. (Link to Publication Site) ● Publication site (DOI): 10.1002/dev.22542 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 39237483 ● Search Scopus @ Elsevier (PMID): 39237483 ● Search Scopus @ Elsevier (DOI): 10.1002/dev.22542 (DOI: 10.1002/dev.22542, PubMed: 39237483)
2.	Hideaki Fujihara, Michiko Matsunaga, Eriko Ueda, Takamasa Kajiwara, K Aya Takeda, Satoshi Watanabe, Kairi Baba, Keisuke Hagihara and Masako Myowa : Altered Gut Microbiota Composition Is Associated with Difficulty in Explicit Emotion Regulation in Young Children., Microorganisms, 11, 9, 2023. (Summary) Executive function (EF) consists of explicit emotion regulation (EER) and cognitive control (CC). Childhood EER in particular predicts mental and physical health in adulthood. Identifying factors affecting EER development has implications for lifelong physical and mental health. Gut microbiota (GM) has attracted attention as a potential biomarker for risk of physical and mental problems in adulthood. Furthermore, GM is related to brain function/structure, which plays a crucial role in emotional processing. However, little is known about how GM compositions are associated with the development of emotion regulation in early childhood. Therefore, in this study, we examined 257 children aged 3-4 to investigate links between GM and risk to EF. EF was measured using the Mother-Reported Behavior Rating Inventory of Executive Function-Preschool version. GM composition (alpha/beta diversity and genus abundance) was evaluated using 16S rRNA gene sequencing and compared between EF-risk and non-risk groups. Our results show that children with EER-risk (an index of inhibitory self-control) had a higher abundance of the genera Actinomyces and Sutterella. Although we have not established a direct link between GM and CC risk, our findings indicate that GM of preschoolers is closely associated with emotional processing and that EERrisk children have more inflammation-related bacteria. (Link to Publication Site) ● Publication site (DOI): 10.3390/microorganisms11092245 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 37764088 ● Search Scopus @ Elsevier (PMID): 37764088 ● Search Scopus @ Elsevier (DOI): 10.3390/microorganisms11092245 (DOI: 10.3390/microorganisms11092245, PubMed: 37764088)
3.	Hideaki Fujihara and 安村明 : 高齢者における飽和脂肪酸の摂取量と抑制機能との関係性, 日本認知症予防学会誌, 11, 1, 12-18, 2021.
4.	Hideaki Fujihara, Akiko Megumi and Akira Yasumura : The acute effect of moderate-intensity exercise on inhibitory control and activation of prefrontal cortex in younger and older adults., Experimental Brain Research, 239, 6, 1765-1778, 2021. (Summary) Exercise has a significant effect on maintaining the health of inhibitory function, a fundamental cognitive ability that supports daily mental processes. While previous studies have shown that a single bout of exercise, called acute exercise, could improve inhibitory control by stimulating the prefrontal cortex (PFC) and the arousal state, few studies have focused on the differences in the effects of exercise by age. In this study, young and older adults (mean age, 22.7 ± 1.4 and 68.7 ± 5.3 years, respectively) engaged in acute moderate-intensity exercise and inhibitory control. Before and at 5 and 30 min after exercise, the participants were asked to complete the reverse Stroop task, and their arousal state and PFC activity were measured using functional near-infrared spectroscopy. The findings showed that the overall inhibitory control improved immediately after performing acute exercise and remained improved even after 30 min. Particularly, there was a difference in the arousal state and middle PFC activity between the two age groups. Especially, the young adults showed an increase in the arousal state post-exercise, while the older adults tended to show an increase in the middle PFC activity. These results suggested that the acute exercise effects on the arousal state and PFC activity may vary depending on the developmental stage, but not for inhibitory control overtime. When these findings are considered, it is important to note that the exercise impact on cognitive control remained the same throughout the generations despite the observed changes in its impact on internal states. (Keyword) Executive Function / NIRS / Exercise / Prefrontal Cortex (Link to Publication Site) ● Publication site (DOI): 10.1007/s00221-021-06086-9 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 33783561 ● Search Scopus @ Elsevier (PMID): 33783561 ● Search Scopus @ Elsevier (DOI): 10.1007/s00221-021-06086-9 (DOI: 10.1007/s00221-021-06086-9, PubMed: 33783561)

Proceeding of International Conference:

1.	Matsunaga Michiko, Hideaki Fujihara, Baba Kairi, Watanabe Satoshi, Takeda K. Aya and Myowa Masako : Gut Microbiota and Emotional Regulation in Early Childhood: A Cross-Sectional and Longitudinal Study, The 13th Annual Flux Congress, Dublin, Ireland, Sep. 2025.
2.	Hideaki Fujihara, Michiko Matsunaga, Eriko Ueda, Takamasa Kajiwara, Aya K. Takeda, Satoshi Watanabe, Kairi Baba, Keisuke Hagihara and Masako Myowa : Early childhood gut microbiota: its association with emotional regulation and cognitive aspects of executive function., 4th edition of the International World of Microbiome Conference, Sofia, Bulgaria, Oct. 2023.
3.	Hideaki Fujihara, Michiko Matsunaga, Eriko Ueda, Takamasa Kajiwara, Aya K. Takeda, Satoshi Watanabe, Kairi Baba, Keisuke Hagihara and Masako Myowa : Altered composition of gut microbiome associated with explicit emotional regulation in Japanese preschool children., Society for Research in Child Development 2023 Biennial Meeting, Salt Lake City, United States, Mar. 2023.
4.	Eriko Ueda, Michiko Matsunaga, Hideaki Fujihara, Takamasa Kajiwara, Aya K. Takeda, Satoshi Watanabe, Kairi Baba, Keisuke Hagihara and Masako Myowa : The maturity of the gut microbiome is associated with temperament in preschool children., The International Human Microbiome Consortium Congress 2022, Kobe, Japan, Nov. 2022.
5.	Hideaki Fujihara, Akiko Megumi and Akira Yasumura : The Sustained Effects of Acute Exercise on Inhibitory Control, Mood and Prefrontal Cortex Activity in Older Adults., International Conference on Dementia, Causes, Concerns and Preventions 2021, Venice, Italy, Apr. 2021.
6.	Hideaki Fujihara, Akiko Megumi and Akira Yasumura : The Relationship between Prefrontal cortex activity and Autism Spectrum Quotient score during an executive function task., 15th Annual Autism Conference, Mar. 2021.

Proceeding of Domestic Conference:

1.	Hideaki Fujihara, 恵明子 and 安村明 : 一過性運動が実行機能と上肢の巧緻性に及ぼす影響: NIRS (近赤外分光法) を用いた検討, 第10回日本認知症予防学会学術集会, 神奈川県 (横浜市), Jun. 2021.
2.	Hideaki Fujihara, 恵明子 and 安村明 : 高齢者における飽和脂肪酸の摂取量と抑制機能との関係性, 日本発達心理学会第 32 回大会, Mar. 2021.

Grants-in-Aid for Scientific Research (KAKEN Grants Database @ NII.ac.jp)

低強度運動による抑うつ気分軽減効果の個人差とその関連要因の解明 (Project/Area Number: 25K23304 )
Search by Researcher Number (11022088)