Tokushima University / Educator and Researcher Directory --- Miyamoto, Youji

Personal Web Page

https://researchmap.jp/read0017487 (researchmap)

Field of Study

○	Dentistry

Subject of Study

○

Book / Paper

Book:

1.	Youji Miyamoto and Masayuki Fukuda : Application of biomaterials for cleft lip and palate surgery, Quintessence,
2.	Keiko Kudoh and Youji Miyamoto : よくわかる口腔インプラント学, 医歯薬出版株式会社, Feb. 2023.
3.	Youji Miyamoto : コラム1「インプラントと非可動性角化粘膜」, Ishiyaku Publishers,Inc., Feb. 2023.
4.	Keiko Kudoh and Youji Miyamoto : 第8章手術および上部構造に関連する併発症とその対応，1「手術中の併発症」, Ishiyaku Publishers,Inc., Feb. 2023.
5.	Naito Kurio and Youji Miyamoto : 第5章口腔インプラント学のための基礎医学，Ⅲ外科手術，1「インプラント手術の準備と感染対策」, Ishiyaku Publishers,Inc., Feb. 2023.
6.	石川邦夫 and Youji Miyamoto : 第2章口腔インプラント学のための基礎医学，Ⅲ材料学，3骨補填材と遮断膜，1)「骨補填材」, Ishiyaku Publishers,Inc., Feb. 2023.
7.	Yoshiko Yamamura and Youji Miyamoto : 周術期口腔機能管理に実際がよくわかる本, Quintessence Publishing CO.,Ltd., Tokyo, Sep. 2020.
8.	Youji Miyamoto : 第5章 1-Ⅲ 「歯根尖(端)切除術」, 医歯薬出版, Sep. 2017.
9.	Youji Miyamoto and Hirokazu Nagai : 第5章 1-Ⅱ 「抜歯述」, 医歯薬出版, Sep. 2017.
10.	Youji Miyamoto : 第5章 1-Ⅰ 「歯・歯周組織とその周囲の解剖」, 医歯薬出版, Sep. 2017.
11.	日本口腔ケア学会編, Youji Miyamoto and 福田雅幸 : 歯ぎしりがひどい高齢者への対応, 永末書店, Apr. 2017.
12.	Youji Miyamoto : インプラント治療後に腎疾患になったら?，第3章:高齢者にインプラント治療を行った後で疾病が発症したら?, Jun. 2014.
13.	Youji Miyamoto : 医科への照会の仕方，Chapter16:医科への照会の仕方, May 2014.
14.	Youji Miyamoto : 抗凝固療法・抗血小板療法時の歯科治療，Chapter5:血液疾患, May 2014.
15.	M. Fukuda and Youji Miyamoto : Care for elderly patients with serious bruxism, Quintessence Publishing CO.,Ltd., Tokyo, 2011.
16.	Kenichi Hamada, Youji Miyamoto and Kenzo Asaoka : 骨修復材, Ishiyaku Publishers,Inc., Tokyo, May 2006.
17.	Youji Miyamoto and 福田雅幸 : うがいの一般的な方法として，誤っているものはどれか, 日総研出版, 2006.
18.	Youji Miyamoto, Kunio Ishikawa, Shigeki Matsuya and Kenji Kawate : In Encyclopedia of Comprehensive structural integrity, 2003.

Academic Paper (Judged Full Paper):

1.	Naoyuki Fukuda, Natsumi Takamaru, Kazuya Akita, Keiko Kudoh, Kunio Ishikawa and Youji Miyamoto : Application and evaluation of carbonate apatite granules for mandibular bone defect reconstruction after jawbone cyst enucleation-a retrospective case series, Oral and Maxillofacial Surgery, Vol.29, No.1, 14, 2024. (Summary) To evaluate the effectiveness of COAp granules in the mandibular bone defects by using computed tomography (CT) images. This study was retrospective case series of mandibular bone defect reconstruction using COAp granules. Six patients with jawbone cysts treated by simultaneous grafting COAp granules after cyst enucleation were enrolled. Patients without grafting COAp granules were excluded. Mandibular bone height including buccolingual bone height, the change of perpendicular distance between the buccolingual line to the alveolar ridge, and the three-dimensional volume of remaining COAp granules were analyzed using CT images obtained at 3, 6, 12, 18, and 24 months postoperatively. Postoperative CT images showed that cortical and cancellous bone-like structures were formed on the grafting area periphery and inside the defect, respectively, with gradual resorption of the COAp granules. Furthermore, there was no evidence of leaving bone defect even at the center of the lesion when the defect was successfully reconstructed by filling it with COAp granules. The percentage volume of remaining COAp granules to the volume at 3 months postoperatively were 76.1 ± 13.1%, 35.8 ± 22.5%, 25.0 ± 13.0%, and 9.9 ± 6.4% at 6, 12, 18, and 24 months postoperatively, and the volume reduction rate increased significantly within 12 months postoperatively. Grafting COAp granules after the enucleation of a jawbone cyst is a good reconstructive treatment option for postoperative prosthetic treatment because COAp granules are gradually replaced by new bone while preserving the contour of the mandibular bone. Not applicable. (Keyword) Humans / Retrospective Studies / Male / Female / Adult / Tomography, X-Ray Computed / Middle Aged / Mandible / Jaw Cysts / Mandibular Reconstruction / Bone Substitutes / Mandibular Diseases / Apatites (Link to Publication Site) ● Publication site (DOI): 10.1007/s10006-024-01306-2 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 39572439 ● Search Scopus @ Elsevier (PMID): 39572439 ● Search Scopus @ Elsevier (DOI): 10.1007/s10006-024-01306-2 (DOI: 10.1007/s10006-024-01306-2, PubMed: 39572439)
2.	Kazuya Akita, Naoyuki Fukuda, Natsumi Takamaru, Keiko Kudoh, Ishikawa Kunio and Youji Miyamoto : Fabrication of a carbonate apatite granules sponge as a new bone substitute and its histological evaluation at rat calvarial bone defects, Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology, 2024. (Link to Publication Site) ● Publication site (DOI): 10.1016/j.ajoms.2024.05.004 (Link to Search Site for Scientific Articles) ● Search Scopus @ Elsevier (DOI): 10.1016/j.ajoms.2024.05.004 (DOI: 10.1016/j.ajoms.2024.05.004)
3.	Takaharu Kudoh and Youji Miyamoto : Evaluation of dose constraint for contralateral neck in the unilateral neck volumetric-modulated arc radiotherapy, Dental Radiology, Vol.63, No.2, 47-53, 2024. (Keyword) Unilateral / Neck / Volumetric-modulated arc therapy / Dose constraint (Tokushima University Institutional Repository) ● Metadata: 119163 (Link to Publication Site) ● Publication site (DOI): 10.11242/dentalradiology.63.47 (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1390862623773836544 ● Search Scopus @ Elsevier (DOI): 10.11242/dentalradiology.63.47 (Tokushima University Institutional Repository: 119163, DOI: 10.11242/dentalradiology.63.47, CiNii: 1390862623773836544)
4.	TANAKA Mariko, Shinya Horiuchi, Masahiro Hiasa, Keiichiro Watanabe, Akihiko Iwasa, Natsumi Takamaru, Hirokazu Nagai, Youji Miyamoto and Eiji Tanaka : 術後に顎関節に疼痛を訴えた顎偏位を伴う骨格性上顎前突症例, The Journal of Chu-Shikoku Orthodontic Society, Vol.35, No.1, 77-86, 2023.
5.	Akira Takahashi, Kumiko Kamada, Naoyuki Fukuda, Keiko Kudoh, Natsumi Takamaru, Naito Kurio, Chieko Sugawara and Youji Miyamoto : Analysis of the sublingual artery using contrast-enhanced computed tomography, Clinical Implant Dentistry and Related Research, Vol.25, No.3, 532-539, 2023. (Summary) This in vivo study aimed to clarify the position of the sublingual artery (SLA) relative to the mandibular bone and to infer the potential risk for injury during dental implant surgery. Contrast-enhanced computed tomography images of the mouth of 50 edentulous patients (100 sides) treated at Tokushima University Hospital were reviewed. Curved planar reconstructed images perpendicular to the alveolar ridge were processed and classified into molar, premolar, canine, and incisor regions. The SLA and its branches were identified, and the distance from the mandible to the SLA was measured. The SLA was located close to the mandible (<2 mm) in the molar, premolar, canine, and incisor segments in 12.0% (95% confidence interval 5.6%-18.4%), 20.6% (12.6%-28.7%), 30.5% (21.3%-39.8%), and 41.8% (28.8%-54.9%) cases, respectively. The SLA was located within ±3 mm craniocaudally to the upper wall of the mandibular canal in the molar and premolar regions in 50% of cases and within ±5 mm craniocaudally to the mylohyoid ridge in the canine and incisor regions in the other cases, with no sex or age-related differences. The vertical distance from the alveolar ridge to the SLA was influenced by sex and age owing to alveolar resorption, indicating that the alveolar ridge is not a reliable reference for predicting SLA position. As the risk of SLA injury always exist during dental implant placement and there is no way to confirm the SLA pathways in a patient, clinicians must avoid injuring the sublingual soft tissue. (Keyword) Dental Implants / Mandible / Alveolar Process / Tomography, X-Ray Computed / Cone-Beam Computed Tomography / Arteries (Link to Publication Site) ● Publication site (DOI): 10.1111/cid.13197 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 36896477 ● Search Scopus @ Elsevier (PMID): 36896477 ● Search Scopus @ Elsevier (DOI): 10.1111/cid.13197 (DOI: 10.1111/cid.13197, PubMed: 36896477)
6.	Atsushi Uesugi, Fumihiko Tsushima, Youji Miyamoto and Hiroyuki Harada : Pollen food allergy syndrome caused by Japanese radish: A case report, Indian Journal of Dermatology, Vol.68, No.1, 123, 2023. (Summary) Pollen food allergy syndrome (PFAS) is a food allergy that manifests as hypersensitivity symptoms of the oropharyngeal mucosa on ingesting specific foods, and findings resemble herpetic gingivostomatitis. Few reports of PFAS caused by consuming radishes are found in the literature. A 31-year-old man presented to our department with stomatitis and pharyngeal pain. He had no history of allergies. Herpetic gingivostomatitis was suspected. He was admitted to the emergency room a few days later complaining of oral and epigastric pain. Symptoms were similar to those reported previously. He reported frequently consuming raw Japanese radish ( L.) which gave rise to his symptoms. Japanese radish was suspected as the allergen. The skin-prick test confirmed the diagnosis of PFAS. PFAS can be diagnosed easily once the food-causing symptoms are identified. Upon encountering widespread erosion in the oral cavity, it is essential to consider PFAS as the possible cause. (Keyword) herpetic gingivostomatitis / Japanese radish / pollen food allergy syndrome / Raphans sativus L. / skin prick test (Link to Publication Site) ● Publication site (DOI): 10.4103/ijd.ijd_405_22 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 37151264 ● Search Scopus @ Elsevier (PMID): 37151264 ● Search Scopus @ Elsevier (DOI): 10.4103/ijd.ijd_405_22 (DOI: 10.4103/ijd.ijd_405_22, PubMed: 37151264)
7.	Naoyuki Fukuda, Natsumi Takamaru, Kazuya Akita, 浦田豊彰, 永井和弘 and Youji Miyamoto : A case of fishbone in the tongue that migrated toward the hyoid bone, Japanese Journal of Oral & Maxillofacial Surgery, Vol.68, No.2, 58-62, 2023. (Keyword) 魚骨 / 異物 / 舌 / 舌骨 / 術中超音波検査 / fishbone / foreign body / tongue / hyoid bone / intraoperative ultrasonography (Link to Publication Site) ● Publication site (DOI): 10.5794/jjoms.69.58 (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1390295823371025920 ● Search Scopus @ Elsevier (DOI): 10.5794/jjoms.69.58 (DOI: 10.5794/jjoms.69.58, CiNii: 1390295823371025920)
8.	Keiko Kudoh, Go Ohe, Natsumi Takamaru, Kazuya Akita, Takaharu Kudoh, Akira Takahashi and Youji Miyamoto : Computed tomography-based morphological analysis for intraoral vertical ramus osteotomy in patients with mandibular prognathism, Oral Science International, Vol.21, No.1, 37-45, 2023. (Link to Publication Site) ● Publication site (DOI): 10.1002/osi2.1176 (Link to Search Site for Scientific Articles) ● Search Scopus @ Elsevier (DOI): 10.1002/osi2.1176 (DOI: 10.1002/osi2.1176)
9.	Naoyuki Fukuda, Keiko Kudoh, Kazuya Akita, Natsumi Takamaru, 石川邦夫 and Youji Miyamoto : Comparison of bioresorbable bone substitutes, carbonate apatite and β-tricalcium phosphate, for alveolar bone augmentation with simultaneous implant placement., Oral Science International, Vol.20, No.2, 1-8, 2023. (Link to Publication Site) ● Publication site (DOI): 10.1002/osi2.1170 (Link to Search Site for Scientific Articles) ● Search Scopus @ Elsevier (DOI): 10.1002/osi2.1170 (DOI: 10.1002/osi2.1170)
10.	Keiko Kudoh, Naoyuki Fukuda, Kazuya Akita, Natsumi Takamaru, Naito Kurio, 石川邦夫 and Youji Miyamoto : Reconstruction of rabbit mandibular bone defects using carbonate apatite honeycomb blocks with an interconnected porous structure., Journal of Materials Science. Materials in Medicine, Vol.34, No.1, 2022. (Summary) Carbonate apatite (COAp) granules are useful as a bone substitute because they can be remodeled to new natural bone in a manner that conforms to the bone remodeling process. However, reconstructing large bone defects using COAp granules is difficult because of their granular shape. Therefore, we fabricated COAp honeycomb blocks (HCBs) with continuous unidirectional pores. We aimed to elucidate the tissue response and availability of COAp HCBs in the reconstruction of rabbit mandibular bone defects after marginal mandibulectomy. The percentages of the remaining COAp area and calcified bone area (newly formed bone) were estimated from the histological images. COAp area was 49.1 ± 4.9%, 30.3 ± 3.5%, and 25.5 ± 8.8%, whereas newly formed bone area was 3.0 ± 0.6%, 24.3 ± 3.3%, and 34.7 ± 4.8% at 4, 8, and 12 weeks, respectively, after implantation. Thus, COAp HCBs were gradually resorbed and replaced by new bone. The newly formed bone penetrated most of the pores in the COAp HCBs at 12 weeks after implantation. By contrast, the granulation tissue scarcely invaded the COAp HCBs. Some osteoclasts invaded the wall of COAp HCBs, making resorption pits. Furthermore, many osteoblasts were found on the newly formed bone, indicating ongoing bone remodeling. Blood vessels were also formed inside most of the pores in the COAp HCBs. These findings suggest that COAp HCBs have good osteoconductivity and can be used for the reconstruction of large mandibular bone defects. The COAp HCB were gradually resorbed and replaced by newly formed bone. (Keyword) Animals / Rabbits / Porosity / Apatites / Bone Substitutes / Bone and Bones / Porifera (Tokushima University Institutional Repository) ● Metadata: 118064 (Link to Publication Site) ● Publication site (DOI): 10.1007/s10856-022-06710-2 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 36586041 ● Summary page in Scopus @ Elsevier: 2-s2.0-85145354870 (Tokushima University Institutional Repository: 118064, DOI: 10.1007/s10856-022-06710-2, PubMed: 36586041, Elsevier: Scopus)
11.	Yoshitaka Suzuki, Kazuo Okura, Yasutomo Yoshihara, Junhel Dalanon, Kazuya Akita, Youji Miyamoto and Yoshizo Matsuka : Survey of oral maxillofacial injury experiences and sports mouthguard use in wakeboarders, International Journal of Sports Dentistry, Vol.15, No.1, 17-24, 2022.
12.	Yoshiko Yamamura, 鴨居耕平, Keiko Kudoh, Naito Kurio, Kumiko Kamada, 横田美保, Atsushi Uesugi and Youji Miyamoto : A Case of Ameloblastoma Removed Using a Three-dimensional Transparent Plastic Jaw Model Which Can Visualize Internal Jawbone Structures, Journal of Oral Health and Biosciences, Vol.35, No.1, 9-13, 2022. (Keyword) ameloblastoma / three-dimensional jaw model / three-dimensional printer / visualization (Tokushima University Institutional Repository) ● Metadata: 117597 (Link to Publication Site) ● Publication site (DOI): 10.20738/johb.35.1_9 (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1390293412207632768 ● Search Scopus @ Elsevier (DOI): 10.20738/johb.35.1_9 (Tokushima University Institutional Repository: 117597, DOI: 10.20738/johb.35.1_9, CiNii: 1390293412207632768)
13.	Yoshiko Yamamura, Keiko Miyoshi, Yasuhiro Mouri, Yasusei Kudo and Youji Miyamoto : miR 155 5p can be involved in acquisition of osseointegration on titanium surface, In Vitro Cellular & Developmental Biology. Animal, Vol.58, No.8, 693-701, 2022. (Summary) Dental implants made of titanium are commonly used. Although titanium implants succeed by osseointegration with bone, the detailed molecular mechanism of osseointegration is unclear. To clarify the involvement of microRNA (miRNA) in the acquisition of osseointegration on titanium, here we compared the miRNA expression profiles of mouse osteoblast-like cells (MC3T3-E1) cultured on titanium-, gold-, and stainless steel-coating glass dishes by microarray analysis. Three kinds of metals, namely titanium, gold, and stainless steel, were coated on the surface of the glass dishes by sputtering with similar roughness and shape of their surface. After MC3T3-E1 cells were cultured on the dishes without coating or coating with titanium, gold, or stainless steel for 6 h, total RNA was extracted, and miRNA expression was analyzed by microarray. To confirm the expression of the selected miRNA during osteogenic differentiation of MC3T3-E1 cells, real-time PCR analysis was performed. Furthermore, the effects of selected miRNA were examined by ectopic overexpression in MC3T3-E1 cells. The microarray analysis revealed that the expressions of miR-155-5p and miR-7023-3p were significantly increased in MC3T3-E1 cells cultured on titanium-coating glass dishes, compared to non-coating, gold-, and stainless steel-coating glass dishes. Interestingly, miR-155-5p was upregulated during osteogenic differentiation of MC3T3-E1 cells. Furthermore, overexpression of miR-155-5p enhanced the expression of Runx2 and Col1a1. In this study, miR-155-5p may be involved in the acquisition of osseointegration on titanium implant via upregulating osteogenic differentiation-related genes. (Link to Publication Site) ● Publication site (DOI): 10.1007/s11626-022-00718-2 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 36053380 ● Search Scopus @ Elsevier (PMID): 36053380 ● Search Scopus @ Elsevier (DOI): 10.1007/s11626-022-00718-2 (DOI: 10.1007/s11626-022-00718-2, PubMed: 36053380)
14.	Yoshiko Yamamura, Makoto Fukui, Takaharu Kudoh, 横田美保, Kumiko Kamada, Kazuya Akita, Naoyuki Fukuda, Natsumi Takamaru, Keiko Kudoh, Naito Kurio and Youji Miyamoto : ピロカルピン塩酸塩を用いた口腔リンス法の有用性と安全性の検討, Oral Care, Vol.16, No.2, 52-56, 2022. (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1520579212289190912 (CiNii: 1520579212289190912)
15.	Tetsuya Nitta, Yoshiko Yamamura, Youji Miyamoto and Hiroshi Kurita : Prevalence of and risk factors for postoperative complications after lower third molar extraction: A multicenter prospective observational study in Japan, Medicine, Vol.101, No.32, e29989, 2022. (Summary) Lower third molar extraction is the most common surgical treatment among routine dental and oral surgical procedures. while the surgical procedures for lower third molar extraction are well established, the difficulty of tooth extraction and the frequency of postoperative complications differ depending on the patient's background. To establish a management protocol for the lower third molars, the prevalence of and risk factors for postoperative complications after lower third molar extraction were investigated in a large number of Japanese patients in a multicenter prospective study. During 6 consecutive months in 2020, 1826 lower third molar extractions were performed at the 20 participating institutions. The medical records of the patients were reviewed, and relevant data were extracted. The prevalence of and risk factors for postoperative complications were analyzed. The prevalence of postoperative complications after lower third molar extraction was 10.0%. Multivariate analysis indicated that age (≤32 vs >32, odds ratio [OR]: 1.428, 95% confidence interval [95% CI]: 1.040-1.962, P < .05), the radiographic anatomical relationship between the tooth roots and mandibular canal (overlapping of the roots and canal vs no close anatomical relationship between the roots and the superior border of the canal, OR: 2.078, 95% CI: 1.333-3.238, P < .01; overlapping of the roots and canal vs roots impinging on the superior border of the canal, OR: 1.599, 95% CI: 1.050-2.435, P < .05), and impaction depth according to the Pell and Gregory classification (position C vs position A, OR: 3.7622, 95% CI: 2.079-6.310, P < .001; position C vs position B, OR: 2.574, 95% CI: 1.574-4.210, P < .001) are significant independent risk factors for postoperative complications after lower third molar extraction. These results suggested that higher age and a deeply impacted tooth might be significant independent risk factors for postoperative complications after lower third molar extraction. (Keyword) Humans / Japan / Mandible / Molar, Third / Postoperative Complications / Prevalence / Prospective Studies / Risk Factors / Tooth Extraction / Tooth, Impacted (Tokushima University Institutional Repository) ● Metadata: 117844 (Link to Publication Site) ● Publication site (DOI): 10.1097/MD.0000000000029989 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 35960058 ● Search Scopus @ Elsevier (PMID): 35960058 ● Search Scopus @ Elsevier (DOI): 10.1097/MD.0000000000029989 (Tokushima University Institutional Repository: 117844, DOI: 10.1097/MD.0000000000029989, PubMed: 35960058)
16.	Masako Fujioka-Kobayashi, Youji Miyamoto, Kunio Ishikawa, Takafumi Satomi and Benoit Schaller : Osteoclast behaviors on the surface of deproteinized bovine bone mineral and carbonate apatite substitutes in vitro, Journal of Biomedical Materials Research. Part A, Vol.110, No.8, 1524-1532, 2022. (Link to Publication Site) ● Publication site (DOI): 10.1002/jbm.a.37392 (Link to Search Site for Scientific Articles) ● Summary page in Scopus @ Elsevier: 2-s2.0-85128206468 (DOI: 10.1002/jbm.a.37392, Elsevier: Scopus)
17.	Takaharu Kudoh, Akihiro Haga, Keiko Kudoh, Akira Takahashi, Motoharu Sasaki, Yasusei Kudo, Hitoshi Ikushima and Youji Miyamoto : Radiomics analysis of [18F]-fluoro-2-deoxyglucose positron emission tomography for the prediction of cervical lymph node metastasis in tongue squamous cell carcinoma, Oral Radiology, 2022. (Summary) This study aimed to create a predictive model for cervical lymph node metastasis (CLNM) in patients with tongue squamous cell carcinoma (SCC) based on radiomics features detected by [F]-fluoro-2-deoxyglucose (F-FDG) positron emission tomography (PET). A total of 40 patients with tongue SCC who underwent F-FDG PET imaging during their first medical examination were enrolled. During the follow-up period (mean 28 months), 20 patients had CLNM, including six with late CLNM, whereas the remaining 20 patients did not have CLNM. Radiomics features were extracted from F-FDG PET images of all patients irrespective of metal artifact, and clinicopathological factors were obtained from the medical records. Late CLNM was defined as the CLNM that occurred after major treatment. The least absolute shrinkage and selection operator (LASSO) model was used for radiomics feature selection and sequential data fitting. The receiver operating characteristic curve analysis was used to assess the predictive performance of the F-FDG PET-based model and clinicopathological factors model (CFM) for CLNM. Six radiomics features were selected from LASSO analysis. The average values of the area under the curve (AUC), accuracy, sensitivity, and specificity of radiomics analysis for predicting CLNM from F-FDG PET images were 0.79, 0.68, 0.65, and 0.70, respectively. In contrast, those of the CFM were 0.54, 0.60, 0.60, and 0.60, respectively. The F-FDG PET-based model showed significantly higher AUC than that of the CFM. The F-FDG PET-based model has better potential for diagnosing CLNM and predicting late CLNM in patients with tongue SCC than the CFM. (Tokushima University Institutional Repository) ● Metadata: 116770 (Link to Publication Site) ● Publication site (DOI): 10.1007/s11282-022-00600-7 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 35254609 ● Summary page in Scopus @ Elsevier: 2-s2.0-85125757133 (Tokushima University Institutional Repository: 116770, DOI: 10.1007/s11282-022-00600-7, PubMed: 35254609, Elsevier: Scopus)
18.	Naoyuki Fukuda, Kunio Ishikawa and Youji Miyamoto : Alveolar ridge preservation in beagle dogs using carbonate apatite bone substitute, Ceramics International, Vol.48, No.2, 1796-1804, 2022. (Link to Publication Site) ● Publication site (DOI): 10.1016/j.ceramint.2021.09.260 (Link to Search Site for Scientific Articles) ● Summary page in Scopus @ Elsevier: 2-s2.0-85116543247 (DOI: 10.1016/j.ceramint.2021.09.260, Elsevier: Scopus)
19.	Natsumi Takamaru, Naoyuki Fukuda, Kazuya Akita, Keiko Kudoh and Youji Miyamoto : Association of PD L1 and ZEB 1 expression patterns with clinicopathological characteristics and prognosis in oral squamous cell carcinoma, Oncology Letters, Vol.23, No.3, 2022. (Summary) Programmed cell death-1 (PD-1) and its ligand programmed cell death 1 ligand 1 (PD-L1) are immune checkpoint inhibitors that play an important role in the host immune avoidance mechanism of tumors. The relationship between PD-L1 expression and malignancy has been reported in various types of cancer, such as lung and gastric cancer. In addition, epithelial-mesenchymal transition (EMT) of cancer cells is deeply involved in the invasion and metastasis of cancer. It has been reported that zinc finger E-box binding homeobox 1 (ZEB-1), an EMT inducer, contributes to metastasis in pancreatic and colon cancer. The present study aimed to investigate the relationship between the expression patterns of two markers, PD-L1 and ZEB-1, and clinicopathological characteristics and prognosis of oral squamous cell carcinoma (OSCC). Biopsy or surgical excision specimens from 169 patients with OSCC were used in the present study. Immunohistochemical staining with monoclonal anti-PD-L1 antibody and anti-ZEB-1 antibody was conducted. Cases with >1% tumor cells positive for PD-L1 and those with >10% tumor cells positive for ZEB-1 were considered positive, respectively. The findings revealed that individual expression of PD-L1 and ZEB-1 in OSCC was not associated with tumor size, degree of differentiation or Yamamoto-Kohama invasion pattern classification. However, co-expression of PD-L1 and ZEB-1 was associated with higher cervical lymph node metastasis and a lower survival rate. In conclusion, the results of the present study indicated that co-expression of PD-L1 and ZEB-1 could serve as a potential marker for the prognosis of patients with OSCC. (Link to Publication Site) ● Publication site (DOI): 10.3892/ol.2022.13195 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 35111244 ● Summary page in Scopus @ Elsevier: 2-s2.0-85123294766 (DOI: 10.3892/ol.2022.13195, PubMed: 35111244, Elsevier: Scopus)
20.	Y Ogino, Y Ayukawa, N Tachikawa, M Shimogishi, Youji Miyamoto, Keiko Kudoh, Naoyuki Fukuda, K Ishikawa and K Koyano : Staged Sinus Floor Elevation Using Novel Low-Crystalline Carbonate Apatite Granules: Prospective Results after 3-Year Functional Loading., Materials, Vol.14, No.19, 5760, 2021. (Tokushima University Institutional Repository) ● Metadata: 116822 (Link to Publication Site) ● Publication site (DOI): 10.3390/ma14195760 (Link to Search Site for Scientific Articles) ● Summary page in Scopus @ Elsevier: 2-s2.0-85116466459 (Tokushima University Institutional Repository: 116822, DOI: 10.3390/ma14195760, Elsevier: Scopus)
21.	Go Ohe, Yasusei Kudo, Kumiko Kamada, Yasuhiro Mouri, Natsumi Takamaru, Keiko Kudoh, Naito Kurio and Youji Miyamoto : Soluble Factor from Oral Cancer Cell Lines Inhibits Interferon-γ Production by OK-432 via CD40/CD40Ligand Pathway, Cancers, Vol.13, No.13, 2021. (Tokushima University Institutional Repository) ● Metadata: 116508 (Link to Publication Site) ● Publication site (DOI): 10.3390/cancers13133301 (Link to Search Site for Scientific Articles) ● Summary page in Scopus @ Elsevier: 2-s2.0-85108890231 (Tokushima University Institutional Repository: 116508, DOI: 10.3390/cancers13133301, Elsevier: Scopus)
22.	Akira Takahashi, Kumiko Kamada, Keiko Kudoh, Takaharu Kudoh, Natsumi Takamaru, Naito Kurio, Chieko Sugawara and Youji Miyamoto : Evaluation of anatomical references for locating the course of the posterior superior alveolar artery for dental implant surgery, International Journal of Oral and Maxillofacial Surgery, Vol.51, No.2, 257-262, 2021. (Summary) This retrospective cohort study aimed to identify the best anatomical reference for predicting the posterior superior alveolar artery (PSAA) location. Computed tomographic images of 90 maxillary sinuses were evaluated. We studied five references, including the alveolar crest, maxillary sinus floor, zygomatoalveolar crest, hard palate and soft palate, and measured the distances between them and the PSAA. Variations in the distance were evaluated by the standard deviation and coefficient of variation (CV). The zygomatoalveolar crest was an unstable reference, owing to its high standard deviation and CV. The smallest CV was for the distance between the alveolar crest and PSAA, although the distance was smaller in edentulous jaws than dentulous jaws. The distance between the sinus floor and PSAA was larger in male and edentulous patients. The PSAA was detected in 40.0%, 44.4%, 54.4% and 56.7% of the sinus walls at the first and second premolar and the first and second molar positions, respectively. At these tooth positions, the respective heights above the hard palate were 11.2 ± 4.9, 8.2 ± 4.9, 6.2 ± 2.8 and 8.1 ± 2.9 mm. The hard palate was the most stable reference for predicting the location of the PSAA, irrespective of sex, age and dentition. (Keyword) Arteries / Cone-Beam Computed Tomography / Dental Implants / Humans / Male / Maxillary Sinus / Retrospective Studies / Sinus Floor Augmentation (Link to Publication Site) ● Publication site (DOI): 10.1016/j.ijom.2021.05.013 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 34083086 ● Summary page in Scopus @ Elsevier: 2-s2.0-85107155071 (DOI: 10.1016/j.ijom.2021.05.013, PubMed: 34083086, Elsevier: Scopus)
23.	Yoshiko Yamamura, Takamitsu Mano, Kumiko Kamada, 横田美保, Naoyuki Fukuda, Natsumi Takamaru, Keiko Kudoh, Naito Kurio and Youji Miyamoto : A clinical study on malignant lymphomas arising in the oral region, Journal of Japan Society for Oral Tumors, Vol.33, No.2, 35-60, 2021. (Summary) We examined the clinical characteristics of 18 cases of malignant lymphomas arising in the oral region which were diagnosed at our department during the 11 years from 2008 to 2018. The patients consisted of 10 males and 8 females whose mean age was 70.2 years. The primary site was the upper gingiva in 10 cases (55.6%), and the initial symptoms were tumor mass and swelling in 15 cases (83.3%). Only 7 cases (38.9%) were clinically diagnosed as malignant lymphoma at first visit, but the other 11 cases were difficult to diagnose correctly. The various clinical symptoms such as mass formation and ulcer made differential diagnosis difficult, and a definitive diagnosis could not be obtained by only a single biopsy. Therefore, we examined whether blood test results might be used as an indicator of the diagnosis or not. Our results showed that LDH in 8 of 17 cases (47.1%) and sIL-2R in 11 of 16 cases (68.8%) were high values. Furthermore, we examined whether lymphocyte-monocyte ratio (LMR) helped the diagnosis or not. Thirteen of 17 cases (76.5%) showed a low value of LMR. There was a significant difference in LMR compared to non-malignant lymphoma patients. LMR in the blood tests was also considered to be a useful marker for the diagnosis. (Keyword) malignant lymphoma / clinical study / oral region / lymphocyte-monocyte ratio (Tokushima University Institutional Repository) ● Metadata: 116069 (Link to Publication Site) ● Publication site (DOI): 10.5843/jsot.33.35 (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1390851398293094784 ● Search Scopus @ Elsevier (DOI): 10.5843/jsot.33.35 (Tokushima University Institutional Repository: 116069, DOI: 10.5843/jsot.33.35, CiNii: 1390851398293094784)
24.	Yoshiko Yamamura, Yasusei Kudo, Keiko Kudoh and Youji Miyamoto : Actinomycotic osteomyelitis of the mandible with bone destruction: Two case reports with a review of the Japanese literatures, Oral Science International, 2021. (Link to Publication Site) ● Publication site (DOI): 10.1002/osi2.1088 (Link to Search Site for Scientific Articles) ● Summary page in Scopus @ Elsevier: 2-s2.0-85099385266 (DOI: 10.1002/osi2.1088, Elsevier: Scopus)
25.	Takaharu Kudoh, Akira Takahashi, Keiko Kudoh and Youji Miyamoto : 強度変調放射線治療に伴う放射線性顎骨壊死の頻度と危険因子の検討, Dental Radiology, Vol.60, No.1, 17-20, 2020. (Tokushima University Institutional Repository) ● Metadata: 115355 (Link to Publication Site) ● Publication site (DOI): 10.11242/dentalradiology.60.17 (Link to Search Site for Scientific Articles) ● Search Scopus @ Elsevier (DOI): 10.11242/dentalradiology.60.17 (Tokushima University Institutional Repository: 115355, DOI: 10.11242/dentalradiology.60.17)
26.	Keiko Kudoh, Kazumi Takaishi, Takaharu Kudoh, Natsumi Takamaru, Kumiko Kamada and Youji Miyamoto : Inferior alveolar nerve paresthesia caused by the extrusion of calcium hydroxide-based paste into themandibular canal: A case report., Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology, Vol.32, No.5, 366-369, 2020. (Link to Publication Site) ● Publication site (DOI): 10.1016/j.ajoms.2020.05.005 (Link to Search Site for Scientific Articles) ● Search Scopus @ Elsevier (DOI): 10.1016/j.ajoms.2020.05.005 (DOI: 10.1016/j.ajoms.2020.05.005)
27.	Takamitsu Mano, Kazuya Akita, Naoyuki Fukuda, Kumiko Kamada, Naito Kurio, Kunio Ishikawa and Youji Miyamoto : Histological comparison of three apatitic bone substitutes with different carbonate contents in alveolar bone defects in a beagle mandible with simultaneous implant installation., Journal of Biomedical Materials Research. Part B, Applied Biomaterials, Vol.108, No.4, 1450-1459, 2020. (Summary) Since bone apatite is a carbonate apatite containing carbonate in an apatitic structure, carbonate content may be one of the factors governing the osteoconductivity of apatitic bone substitutes. The aim of this study was to evaluate the effects of carbonate content on the osteoconductivity of apatitic bone substitutes using three commercially available bone substitutes for the reconstruction of alveolar bone defects of a beagle mandible with simultaneous dental implant installation. NEOBONE, Bio-Oss, and Cytrans that contain 0.1, 5.5, and 12.0 mass% of carbonate, respectively, were used in this study. The amount of newly formed bone in the upper portion of the alveolar bone defect of the beagle's mandible was 0.7, 6.6, and 39.4% at 4 weeks after surgery and 4.7, 39.5, and 75.2% at 12 weeks after surgery for NEOBONE, Bio-Oss, and Cytrans, respectively. The results indicate that bone-to-implant contact ratio was the largest for Cytrans. Additionally, the continuity of the alveolar ridge was restored in the case of Cytrans, whereas the continuity of the alveolar ridge was not sufficient when using NEOBONE and Bio-Oss. Both Cytrans and Bio-Oss that have a relatively larger carbonate content in their apatitic structure was resorbed with time. We concluded that carbonate content is one of important factors governing the osteoconductivity of apatitic bone substitutes. (Tokushima University Institutional Repository) ● Metadata: 113813 (Link to Publication Site) ● Publication site (DOI): 10.1002/jbm.b.34492 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 31622016 ● Search Scopus @ Elsevier (PMID): 31622016 ● Search Scopus @ Elsevier (DOI): 10.1002/jbm.b.34492 (Tokushima University Institutional Repository: 113813, DOI: 10.1002/jbm.b.34492, PubMed: 31622016)
28.	Naito Kurio, Kumiko Kamada, Takumi Kitagawa, Yasusei Kudo, Naozumi Ishimaru and Youji Miyamoto : A case of microcystic adnexal carcinoma arising in the upper gingiva, Japanese Journal of Oral & Maxillofacial Surgery, Vol.66, No.9, 455-459, 2020. (Summary) <p>Microcystic adnexal carcinoma (MAC) is a rare malignant tumor of skin appendages. MAC grows slowly, but is locally aggressive. The metastatic potential is low, but the recurrence rates are very high owing to insufficient dissection. The most common location of MAC is the skin of the midface of middle-aged adults. There has been no report about MAC arising in the gingiva. We report here an extremely rare case of MAC of the upper gingiva in a 53-year-old woman. She presented to our hospital with a 6-year history of a gradually increasing gingival mass. Intraoral examination revealed a smooth, poorly circumscribed mass with white granules resembling Fordyce spots on her upper gingiva. There was no bone destruction or regional lymph node swelling. The histopathological diagnosis was a tumor of skin appendages. Tumor resection was performed. Postoperative pathological examination revealed that the tumor differentiated into hair follicles and the sweat-gland-like structures and deeply infiltrated into muscle, perineural spaces, and bone. Since the surgical margins were positive, additional resection was performed after preoperative mapping biopsy. Finally, the tumor was completely excised. No tumor recurrence or metastasis have been observed over 1 year.</p> (Link to Publication Site) ● Publication site (DOI): 10.5794/jjoms.66.455 (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1391975276372989696 ● Search Scopus @ Elsevier (DOI): 10.5794/jjoms.66.455 (DOI: 10.5794/jjoms.66.455, CiNii: 1391975276372989696)
29.	Kazuya Akita, Naoyuki Fukuda, Kumiko Kamada, Naito Kurio, Keiko Kudoh, Tsuru Kanji, Ishikawa Kunio and Youji Miyamoto : Fabrication of porous carbonate apatite granules using microfiber and its histological evaluations in rabbit calvarial bone defects, Journal of Biomedical Materials Research. Part A, Vol.108, No.3, 709-721, 2020. (Summary) Carbonate apatite (CO Ap) granules are known to show good osteoconductivity and replaced to new bone. On the other hand, it is well known that a porous structure allows bone tissue to penetrate its pores, and the optimal pore size for bone ingrowth is dependent on the composition and structure of the scaffold material. Therefore, the aim of this study was to fabricate various porous CO Ap granules through a two-step dissolution-precipitation reaction using CaSO as a precursor and 30-, 50-, 120-, and 205-μm diameter microfibers as porogen and to find the optimal pore size of CO Ap. Porous CO Ap granules were successfully fabricated with pore size 8.2-18.7% smaller than the size of the original fiber porogen. Two weeks after the reconstruction of rabbit calvarial bone defects using porous CO Ap granules, the largest amount of mature bone was seen to be formed inside the pores of CO Ap (120) [porous CO Ap granules made using 120-μm microfiber] followed by CO Ap (50) and CO Ap (30). At 4 and 8 weeks, no statistically significant difference was observed based on the pore size, even though largest amount of mature bone was formed in case of CO Ap (120). It is concluded, therefore, that the optimal pore size of the CO Ap is that of CO Ap (120), which is 85 μm. (Tokushima University Institutional Repository) ● Metadata: 114682 (Link to Publication Site) ● Publication site (DOI): 10.1002/jbm.a.36850 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 31756282 ● Summary page in Scopus @ Elsevier: 2-s2.0-85076129237 (Tokushima University Institutional Repository: 114682, DOI: 10.1002/jbm.a.36850, PubMed: 31756282, Elsevier: Scopus)
30.	Takayuki Nakagawa, Keiko Kudoh, Naoyuki Fukuda, Noriko Tachikawa, Kiyoshi Koyano, Yasuyuki Matsushita, Kunio Ishikawa and Youji Miyamoto : Application of low-crystalline carbonate apatite granules in 2-stage sinus floor augmentation: a prospective clinical trial and histomorphometric evaluation., Journal of Periodontal & Implant Science, Vol.49, No.6, 382-396, 2019. (Summary) The purpose of this study was to elucidate the efficacy and safety of carbonate apatite (COAp) granules in 2-stage sinus floor augmentation through the radiographic and histomorphometric assessment of bone biopsy specimens. Two-stage sinus floor augmentation was performed on 13 patients with a total of 17 implants. Radiographic assessment using panoramic radiographs was performed immediately after augmentation and was also performed 2 additional times, at 7±2 months and 18±2 months post-augmentation, respectively. Bone biopsy specimens taken from planned implant placement sites underwent micro-computed tomography, after which histological sections were prepared. Postoperative healing of the sinus floor augmentation was uneventful in all cases. The mean preoperative residual bone height was 3.5±1.3 mm, and this was increased to 13.3±1.7 mm by augmentation with the COAp granules. The mean height of the augmented site had decreased to 10.7±1.9 mm by 7±2 months after augmentation; however, implants with lengths in the range of 6.5 to 11.5 mm could still be placed. The mean height of the augmented site had decreased to 9.6±1.4 mm by 18±2 months post-augmentation. No implant failure or complications were observed. Few inflammatory cells or foreign body giant cells were observed in the bone biopsy specimens. Although there were individual differences in the amount of new bone detected, new bone was observed to be in direct contact with the COAp granules in all cases, without an intermediate layer of fibrous tissue. The amounts of bone and residual COAp were 33.8%±15.1% and 15.3%±11.9%, respectively. In this first demonstration, low-crystalline COAp granules showed excellent biocompatibility, and bone biopsy showed them to be replaced with bone in humans. COAp granules are a useful and safe bone substitute for two-stage sinus floor augmentation. ICTRP Identifier: JPRN-UMIN000019281. (Tokushima University Institutional Repository) ● Metadata: 114105 (Link to Publication Site) ● Publication site (DOI): 10.5051/jpis.2019.49.6.382 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 31886030 ● Search Scopus @ Elsevier (PMID): 31886030 ● Search Scopus @ Elsevier (DOI): 10.5051/jpis.2019.49.6.382 (Tokushima University Institutional Repository: 114105, DOI: 10.5051/jpis.2019.49.6.382, PubMed: 31886030)
31.	Kunio Ishikawa, Melvin L. Munar, Kanji Tsuru and Youji Miyamoto : Fabrication of carbonate apatite honeycomb and its tissue response., Journal of Biomedical Materials Research. Part A, Vol.107, No.5, 1014-1020, 2019. (Summary) Carbonate apatite (CO Ap) block can be used as a bone substitute because it can be remodeled to new natural bone in a manner conforming with the bone remodeling process. Among the many porous structures available, honeycomb (HC) structure is advantageous for rapid replacement of CO Ap to bone. In this study, the feasibility to fabricate a CO Ap HC was studied, along with its initial tissue response in rabbit femur bone defect. First, a mixture of Ca(OH) and a wax-based binder was extruded from a HC mold. Then the fabricated HC was heated for binder removal and carbonation at 450°C in a mixed O -CO atmosphere, forming a CaCO HC. When the CaCO HC was immersed in 1 mol/L Na PO solution at 80°C for 7 days, its composition changed from CaCO to CO Ap, maintaining the structure of the original CaCO HC. Compressive strengths of the CaCO and CO Ap HCs were 65.2 ± 7.4 MPa and 88.7 ± 4.7 MPa, respectively. When the rabbit femur bone defect was reconstructed with the CO Ap HC, new bone penetrated the CO Ap HC completely. Osteoclasts and osteoblasts were found on the surface of the newly formed bone and osteocytes were also found in the newly formed bone, indicating ongoing bone remodeling. Furthermore, blood vessels were formed inside the pores of CO Ap HC. Therefore, CO Ap HC has good potential as an ideal bone substitute. © 2019 Wiley Periodicals, Inc. J Biomed Mater Res Part A: 107A: 1014-1020, 2019. (Link to Publication Site) ● Publication site (DOI): 10.1002/jbm.a.36640 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 30706693 ● Summary page in Scopus @ Elsevier: 2-s2.0-85061979238 (DOI: 10.1002/jbm.a.36640, PubMed: 30706693, Elsevier: Scopus)
32.	Naoyuki Fukuda, Kunio Ishikawa, Kazuya Akita, Kumiko Kamada, Naito Kurio, Yoshihide Mori and Youji Miyamoto : Effects of acidic calcium phosphate concentration on setting reaction and tissue response to β-tricalcium phosphate granular cement., Journal of Biomedical Materials Research. Part B, Applied Biomaterials, 2019. (Summary) Beta-tricalcium phosphate granular cement (β-TCP GC), consisting of β-TCP granules and an acidic calcium phosphate (Ca-P) solution, shows promise in the reconstruction of bone defects as it sets to form interconnected porous structures, that is, β-TCP granules are bridged with dicalcium phosphate dihydrate (DCPD) crystals. In this study, the effects of acidic Ca-P solution concentration (0-600 mmol/L) on the setting reaction and tissue response to β-TCP GC were investigated. The β-TCP GC set upon mixing with its liquid phase, based on the formation of DCPD crystals, which bridged β-TCP granules to one another. Diametral tensile strength of the set β-TCP GC was relatively the same, at ∼0.6 MPa, when the Ca-P concentration was 20-600 mmol/L. Due to the setting ability, reconstruction of the rat's calvarial bone defect using β-TCP GC with 20, 200, and 600 mmol/L Ca-P solution was much easier compared to that with β-TCP granules without setting ability. Four weeks after the reconstruction, the amount of new bone was the same, ∼17% in both β-TCP GC and β-TCP granules groups. Cellular response to β-TCP granules and β-TCP GC using the 20 mmol/L acidic Ca-P solution was almost the same. However, β-TCP GC using the 200 and 600 mmol/L acidic Ca-P solution showed a more severe inflammatory reaction. It is concluded, therefore, that β-TCP GC, using the 20 mmol/L acidic Ca-P solution, is recommended as this concentration allows surgical techniques to be performed easily and provides good mechanical strength, and the similar cellular response to β-TCP granules. © 2019 Wiley Periodicals, Inc. J Biomed Mater Res Part B, 2019. (Tokushima University Institutional Repository) ● Metadata: 116068 (Link to Publication Site) ● Publication site (DOI): 10.1002/jbm.b.34361 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 30884116 ● Search Scopus @ Elsevier (PMID): 30884116 ● Search Scopus @ Elsevier (DOI): 10.1002/jbm.b.34361 (Tokushima University Institutional Repository: 116068, DOI: 10.1002/jbm.b.34361, PubMed: 30884116)
33.	Keiko Kudoh, Naoyuki Fukuda, Shohei Kasugai, Noriko Tachikawa, Kiyoshi Koyano, Yasuyuki Matsushita, Yoichiro Ogino, Kunio Ishikawa and Youji Miyamoto : Maxillary Sinus Floor Augmentation Using Low-Crystalline Carbonate Apatite Granules With Simultaneous Implant Installation: First-in-Human Clinical Trial., Journal of Oral and Maxillofacial Surgery, Vol.77, No.5, 985.e1-985.e11, 2018. (Summary) Carbonate apatite (COAp), an inorganic component of human bone, can be fabricated in chemically pure form from calcium carbonate block via a dissolution-precipitation reaction. A first-in-human clinical trial was conducted in which low-crystalline COAp granules were evaluated for safety and efficacy in sinus floor augmentation and simultaneous implant installation. Procedures were performed in 8 patients (9 implants) with 2 granule sizes: small (300 to 600 μm) and medium (600 to 1,000 μm). Panoramic radiographic assessment was performed immediately after augmentation, 7 ± 2 months after augmentation, 6 ± 2 months after prosthetic loading, and 12 ± 2 months after prosthetic loading. Postoperative healing was uniformly uneventful, with no abnormal bleeding, pain, or swelling, and all implants achieved successful osseointegration. The mean residual maxillary molar bone height was 5.2 ± 0.8 mm preoperatively and increased to 14.0 ± 1.9 mm after augmentation. Implants 9.0 to 11.5 mm in length were placed. The post-augmentation height decreased to 12.4 ± 1.3 mm at 7 ± 2 months; after prosthetic loading, it decreased to 11.9 ± 0.8 mm at 6 ± 2 months and 11.7 ± 0.6 mm at 12 ± 2 months. No abnormal bone resorption of the augmented areas was observed, and bone height supporting the implants was maintained. The overall implant survival rate was 100%, with no implant failures or complications during the first year. Low-crystalline COAp granules were useful and safe for sinus floor augmentation and simultaneous implant installation, providing a promising bone substitute for dental implant surgery. (Keyword) Apatites / Dental Implantation, Endosseous / Dental Implants / Dental Restoration Failure / Follow-Up Studies / Humans / Maxillary Sinus / Sinus Floor Augmentation / Treatment Outcome (Link to Publication Site) ● Publication site (DOI): 10.1016/j.joms.2018.11.026 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 30597134 ● Summary page in Scopus @ Elsevier: 2-s2.0-85061215753 (DOI: 10.1016/j.joms.2018.11.026, PubMed: 30597134, Elsevier: Scopus)
34.	Youji Miyamoto, Kazuya Akita, 福田直之, Kumiko Kamada and Naito Kurio : 新規骨補填材としての炭酸アパタイトの開発と骨再生医療に向けて, Journal of the Japanese Academy of Maxillofacial Prosthetics, Vol.41, No.2, 15-19, 2018.
35.	Masako Fujioka Kobayashi, Kanji Tsuru, Hirokazu Nagai, Kenji Fujisawa, Takaharu Kudoh, Go Ohe, Kunio Ishikawa and Youji Miyamoto : Fabrication and Evaluation of Carbonate Apatite-coated Calcium Carbonate Bone Substitutes for Bone Tissue Engineering, Journal of Tissue Engineering and Regenerative Medicine, Vol.12, No.10, 2077-2087, 2018. (Summary) Carbonate apatite-coated calcium carbonate (CO Ap/CaCO ) was fabricated through a dissolution-precipitation reaction using CaCO granules as a precursor to accelerate bone replacement based on superior osteoconductivity of the CO Ap shell, along with Ca release from the CaCO core and quicker resorption of the CaCO core. In the present study, CaCO , 10% CO Ap/CaCO , 30% CO Ap/CaCO , and CO Ap granules were fabricated and examined histologically to evaluate their potential as bone substitutes. Larger contents of CaCO in the granules resulted in higher Ca release and promoted cell proliferation of murine preosteoblasts at 6 days compared with CO Ap. Interestingly, in a rabbit femur defect model, 10% CO Ap/CaCO induced significantly higher new bone formation and higher material resorption compared with CO Ap at 8 weeks. Nevertheless, CO Ap showed a superior osteoconductive potential compared with 10% CO Ap/CaCO at 8 weeks. All tested granules were most likely resorbed by cell mediation including multinucleated giant cell functions. Therefore, we conclude that CO Ap/CaCO has a positive potential for bone tissue engineering based on well-controlled calcium release, bone formation, and material resorption. (Link to Publication Site) ● Publication site (DOI): 10.1002/term.2742 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 30058260 ● Summary page in Scopus @ Elsevier: 2-s2.0-85052842255 (DOI: 10.1002/term.2742, PubMed: 30058260, Elsevier: Scopus)
36.	Kenji Fujisawa, Kazuya Akita, Naoyuki Fukuda, Kumiko Kamada, Takaharu Kudoh, Go Ohe, Takamitsu Mano, Kanji Tsuru, Kunio Ishikawa and Youji Miyamoto : Compositional and histological comparison of carbonate apatite fabricated by dissolutionprecipitation reaction and Bio-Oss®., Journal of Materials Science. Materials in Medicine, Vol.29, No.8, 121, 2018. (Summary) Carbonate apatite (COAp) is an inorganic component of bone. This study aimed to compare the composition and tissue response to of COAp (COAp-DP) fabricated by the dissolution-precipitation reaction using calcite as a precursor and Bio-Oss®, which is widely used in orthopedic and dental fields as a synthetic bone substitute. X-ray diffraction and Fourier transform infrared results showed that COAp-DP and Bio-Oss® were both B-type carbonate apatite with low crystallinity. The average sizes of COAp-DP and Bio-Oss® granules were 450 ± 58 and 667 ± 168μ m, respectively, and their carbonate contents were 12.1 ± 0.6 and 5.6 ± 0.1 wt%, respectively. COAp-DP had a larger amount of CO than Bio-Oss® but higher crystallinity than Bio-Oss®. When a bone defect made at the femur of rabbits was reconstructed with COAp-DP and Bio-Oss®, COAp-DP granules were partially replaced with bone, whereas Bio-Oss® remained at 8 weeks after implantation. COAp-DP granules elicited a significantly larger amount of new bone formation at the cortical bone portion than Bio-Oss® at 4 weeks after the implantation. The results obtained in the present study demonstrated that COAp-DP and Bio-Oss® showed different behavior even though they were both classified as COAp. The CO content in COAp played a more important role than the crystallinity of COAp for replacement to bone and high osteoconductivity. (Link to Publication Site) ● Publication site (DOI): 10.1007/s10856-018-6129-2 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 30032409 ● Summary page in Scopus @ Elsevier: 2-s2.0-85050411033 (DOI: 10.1007/s10856-018-6129-2, PubMed: 30032409, Elsevier: Scopus)
37.	Tetsuya Tamatani, Natsumi Takamaru, Go Ohe, Kazuya Akita, Takayuki Nakagawa and Youji Miyamoto : Expression of CD44,CD44v9ABCG2, CD24,Bmi-1 and ALDH1 in stage andoral spuamous cell carcinoma and their association with clinicopathological factors, Oncology Letters, Vol.16, No.1, 1133-1140, 2018. (Summary) Cancer stem cells (CSCs) exhibit self-replication, self-differentiation, drug resistance and immune evasion activities. In recent years CSCs have become increasingly important for the treatment of malignant tumors. CSCs express specific markers, including cluster of differentiation (CD)44, CD44 variant 9 (CD44v9), ATP-binding cassette sub-family G member 2 (ABCG2), CD24, B lymphoma Mo-MLV insertion region 1 homolog (BMI-1) and aldehyde dehydrogenase 1 (ALDH1). However, the prognostic value of their expression in patients with oral squamous cell carcinoma (OSCC) are not well known. The present study evaluated these markers in stage I and II patients with OSCC and examined the association between T classification, histological differentiation, classification of invasion mode, lymph node metastasis and disease-free survival rate. Tissue specimens were obtained from 70 patients with stage I or II OSCC following either surgery or biopsy. Immunohistochemistry was performed and positive staining was defiend as 10% positive cells. CD44 and CD44v9 expressions were strongly detected in all OSCC tissues compared with normal epithelial cells. A total of 22 (31.4%) cases expressed ABCG2 and there was a significant association between ABCG2 expression and invasion. A total of 41 cases (59.0%) expressed CD24 and there was a significant association between CD24 expression and invasion. A total of 33 cases (47.1%) expressed BMI-1 and there was a significant association between BMI-1 expression and the disease-free survival rate. A total of 18 cases (25.7%) expressed ALDH1. Although there was no association between ALDH1 expression and T classification, there were significant associations between ALDH1 expression and histological differentiation, invasion mode, metastasis and the disease-free survival rate. Multivariate analysis revealed that ALDH1 expression was the only prognostic factor for disease-free survival rate. The results of the present study suggest that the positivity of ALDH1 detected in patients with OSCC correlates with the number of cells undergoing epithelial mesenchymal transition and metastasis. These findings indicated that the expression of ALDH1 may be an effective prognostic marker indicating the survival of patients with stage I and II OSCC. (Tokushima University Institutional Repository) ● Metadata: 113599 (Link to Publication Site) ● Publication site (DOI): 10.3892/ol.2018.8703 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 29963189 ● Summary page in Scopus @ Elsevier: 2-s2.0-85047608360 (Tokushima University Institutional Repository: 113599, DOI: 10.3892/ol.2018.8703, PubMed: 29963189, Elsevier: Scopus)
38.	Daisuke Uchida, Nobuyuki Kuribayashi, Makoto Kinouchi, Y Sawatani, M Shimura, T Mori, T Hasegawa, Youji Miyamoto and H Kawamata : Effect of a novel orally bioavailable CXCR4 inhibitor, AMD070, on the metastasis of oral cancer cells., Oncology Reports, Vol.40, No.1, 303-308, 2018. (Summary) We have previously demonstrated that the stromal cell-derived factor (SDF-1)/CXCR4 system is involved in the metastasis of head and neck cancer. Additionally, it has been revealed that the blockade of CXCR4 by subcutaneous daily injection with AMD3100, a CXCR4 antagonist, may be effective in preventing metastasis in CXCR4-related head and neck cancer. Recent investigations have suggested that AMD070, a novel orally bioavailable inhibitor of CXCR4, may be minimally invasive compared with AMD3100. In the present study, we examined the effect of AMD070 on metastasis induced by the SDF-1/CXCR4 axis in B88-SDF-1 oral cancer cells, which express high levels of SDF-1 and CXCR4. Although treatment with AMD070 did not affect the anchorage-dependent growth of B88-SDF-1 cells, it significantly suppressed the anchorage-independent growth. Moreover, the SDF-1/CXCR4-dependent migration and invasion of B88-SDF-1 cells was significantly inhibited following treatment with AMD070. Subsequently, we performed an experimental therapy using AMD070 to prevent the distant metastasis of B88-SDF-1 cells in vivo. Daily oral administration of AMD070 significantly inhibited the lung metastasis of B88-SDF-1 cells in nude mice. These results indicated that AMD070 could be useful as a novel orally bioavailable inhibitor of oral cancer metastasis. (Keyword) Administration, Oral / Animals / Biological Availability / Cell Line, Tumor / Heterocyclic Compounds, 1-Ring / Humans / Lung Neoplasms / Mice / Mouth Neoplasms / Neoplasm Metastasis / Receptors, CXCR4 / Xenograft Model Antitumor Assays (Link to Publication Site) ● Publication site (DOI): 10.3892/or.2018.6400 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 29749473 ● Summary page in Scopus @ Elsevier: 2-s2.0-85047937631 (DOI: 10.3892/or.2018.6400, PubMed: 29749473, Elsevier: Scopus)
39.	Akira Takahashi, Chieko Sugawara, Kazuya Akita, Kumiko Kamada, Keiko Kudoh, Tetsuya Tamatani and Youji Miyamoto : Prevalence and imaging characteristics of nasopharyngeal and eustachian tube tonsilloliths in 2244 patients determined using computed tomography, Dento Maxillo Facial Radiology, Vol.47, 20180052, 2018. (Summary) Nasopharyngeal tonsilloliths (NT) and eustachian tube tonsilloliths (ET) are not as well-known to radiologists as palatine and lingual tonsilloliths. The aim of this investigation was to determine the prevalence and imaging characteristics of NT and ET using CT and panoramic radiographs. We retrospectively assessed the scans of 2244 patients who underwent consecutive CT and panoramic radiographs of the maxillofacial region. The prevalence, size, number, and position of NT and ET were analysed. NT and ET were detected in 14 (0.6%) and 6 (0.3%) of 2244 patients on CT, respectively, but they were undetectable on panoramic radiographs. No significant difference was found in the prevalence with respect to sex. Although there was also no significant difference in the prevalence among age groups, tonsilloliths were most commonly noted in patients over 40 years old; they appeared as small and round calcified bodies, ranging from 1 to 3 mm in diameter. All NT were found 0 to 3 mm beneath the nasopharyngeal mucosal surface. The prevalence of NT and ET on CT was lower than that of palatine and lingual tonsilloliths. However, since they are encountered more frequently than clinically significant calcifying diseases such as retropharyngeal calcific tendinitis, clinicians should be able to correctly diagnose NT and ET based on their anatomical features. (Keyword) nasopharynx / eustachian tube / tonsil / calculi / computed tomography / X-Ray (Tokushima University Institutional Repository) ● Metadata: 113564 (Link to Publication Site) ● Publication site (DOI): 10.1259/dmfr.20180052 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 29714075 ● Search Scopus @ Elsevier (PMID): 29714075 ● Search Scopus @ Elsevier (DOI): 10.1259/dmfr.20180052 (Tokushima University Institutional Repository: 113564, DOI: 10.1259/dmfr.20180052, PubMed: 29714075)
40.	Akira Takahashi, Chieko Sugawara, Keiko Kudoh, Yoshiko Yamamura, Go Ohe, Tetsuya Tamatani and Youji Miyamoto : Lingual tonsillolith: prevalence and imaging characteristics evaluated on 2244 pairs of panoramic radiographs and CT images, Dento Maxillo Facial Radiology, Vol.47, No.1, 20170251, 2018. (Summary) Lingual tonsilloliths are not as well-known to radiologists than palatine tonsilloliths, although they might be common in clinical practice. The aim of this investigation was to clarify the prevalence and imaging characteristics of lingual tonsilloliths using panoramic radiographs and CT images. This study included 2244 patients without pathology at the base of tongue who had undergone panoramic radiography and CT of the maxillofacial region. The size, number and position of lingual tonsilloliths relative to the mandible and tongue were evaluated. Lingual tonsilloliths were observed in 33 (1.5%) and 108 (4.8%) of all patients on panoramic radiographs and CT images, respectively. The prevalence was higher in patients aged ≥40 years than in those aged < 40 years (χ, p < 0.01). They appeared as small, round- or rod-shaped calcified bodies, and they always located closely anterior (1-17 mm) to the anterior border of oropharyngeal airway on panoramic radiographs. Lingual tonsilloliths were superimposed over the surrounding soft tissue inferior to the body of the mandible, posteroinferior to the angle of the mandible and posterior to the mandible in 16 (48.5%), 15 (45.5%) and 1 (3.0%) individual, respectively. A significant correlation was observed between the detectability on panoramic radiographs and size (Spearman's r = 0.961, p < 0.01) of tonsilloliths, as revealed by CT images. Lingual tonsilloliths commonly appear on CT. They also appear on panoramic radiography and may superimpose the surrounding soft tissue of the mandible. Although lingual tonsilloliths may resemble other pathological calcifications including submandibular sialoliths and lingual osseous cholistoma, they can be differentiated by carefully observing panoramic radiographs. When clinicians detect calcified bodies near the base of tongue, lingual tonsilloliths should be included in the differential diagnoses. (Keyword) panoramic radiography / X Ray Computed tomography / tonsil / tongue / calculi (Tokushima University Institutional Repository) ● Metadata: 113565 (Link to Publication Site) ● Publication site (DOI): 10.1259/dmfr.20170251 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 28937280 ● Summary page in Scopus @ Elsevier: 2-s2.0-85040003219 (Tokushima University Institutional Repository: 113565, DOI: 10.1259/dmfr.20170251, PubMed: 28937280, Elsevier: Scopus)
41.	Shinya Sento, Naoya Kitamura, Tetsuya Yamamoto, Koichi Nakashiro, Hiroyuki Hamakawa, Soichiro Ibaragi, Akira Sasaki, Natsumi Takamaru, Youji Miyamoto, Isamu Kodani, Kazuo Ryoke, Katsuaki Mishima and Yoshiya Ueyama : Palonosetron Prevents Highly Emetogenic Chemotherapy-induced Nausea and Vomiting in Oral Cancer Patients, Anticancer Research, Vol.37, No.12, 6977-6981, 2017. (Summary) To evaluate the efficacy of palonosetron in preventing acute and delayed nausea and vomiting in patients receiving highly emetogenic chemotherapy (HEC) in oral cancer patients. Oral cancer patients receiving HEC were enrolled; among the 40 patients, 87 courses of chemotherapy were administered. On day 1, 0.75 mg palonosetron was intravenously administrated just before chemotherapy. The primary endpoint was the proportion of patients with a complete response (CR) and the secondary endpoint was the proportion of patients with complete control (CC) during the acute and delayed phase. During the acute phase, 86 of 87 courses (98.9%) had CR and 84 of 87 courses (96.6%) had CC. During the delayed phase, 84 of 87 courses (96.6%) had CR and 70 of 87 courses (80.5%) had CC. Palonosetron is effective at preventing HEC-induced chemotherapy-induced nausea and vomiting (CINV) in oral cancer chemotherapeutic regimens in the acute and delayed phases. (Keyword) Administration, Intravenous / Adult / Aged / Aged, 80 and over / Antineoplastic Agents / Cisplatin / Drug Therapy, Combination / female / Humans / Isoquinolines / male / Middle Aged / Mouth Neoplasms / Nausea / Palonosetron / Quinuclidines / Serotonin Antagonists / Treatment Outcome / Vomiting (Link to Publication Site) ● Publication site (DOI): 10.21873/anticanres.12165 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 29187483 ● Summary page in Scopus @ Elsevier: 2-s2.0-85038130164 (DOI: 10.21873/anticanres.12165, PubMed: 29187483, Elsevier: Scopus)
42.	Keiko Kudoh, Kumiko Kamada, Natsumi Takamaru, Yoshiko Yamamura, Go Ohe, Takaharu Kudoh, Akira Takahashi, Tetsuya Tamatani, Kenji Fujisawa and Youji Miyamoto : 徳島県における口腔がん検診の現状, 日本歯科人間ドック学会誌, Vol.12, No.1, 21-25, 2017.
43.	Natsumi Takamaru, Tetsuya Tamatani, Go Ohe, Yoshiko Yamamura, Keiko Kudoh and Youji Miyamoto : Single non-contact Nd: YAG laser irradiation treatment for venous malformations in the oral cavity, Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology, Vol.29, No.5, 415-419, 2017. (Link to Publication Site) ● Publication site (DOI): 10.1016/j.ajoms.2017.05.010 (Link to Search Site for Scientific Articles) ● Search Scopus @ Elsevier (DOI): 10.1016/j.ajoms.2017.05.010 (DOI: 10.1016/j.ajoms.2017.05.010)
44.	Satoko Kujiraoka, Takaaki Tsunematsu, Yukiko Sato, Maki Yoshida, Ayataka Ishikawa, Rei Tohyama, Michio Tanaka, Yutaka Kobayashi, Tomoyuki Kondo, Aya Ushio, Kunihiro Otsuka, Mie Kurosawa, Masako Saito, Akiko Yamada, Rieko Arakaki, Hirokazu Nagai, Hiromasa Nikai, Kengo Takeuchi, Toshitaka Nagao, Youji Miyamoto, Naozumi Ishimaru and Yasusei Kudo : Establishment and characterization of a clear cell odontogenic carcinoma cell line with EWSR1-ATF1 fusion gene., Oral Oncology, Vol.69, 46-55, 2017. (Summary) To the best of our knowledge, this is the first report on the establishment of a CCOC cell line. CCOC-T cells serve as a useful in vitro model for understanding the pathogenesis and nature of MOT. (Tokushima University Institutional Repository) ● Metadata: 111726 (Link to Publication Site) ● Publication site (DOI): 10.1016/j.oraloncology.2017.04.003 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 28559020 ● Search Scopus @ Elsevier (PMID): 28559020 ● Search Scopus @ Elsevier (DOI): 10.1016/j.oraloncology.2017.04.003 (Tokushima University Institutional Repository: 111726, DOI: 10.1016/j.oraloncology.2017.04.003, PubMed: 28559020)
45.	Akira Takahashi, Chieko Sugawara, Takaharu Kudoh, Go Ohe, Natsumi Takamaru, Tetsuya Tamatani, Hirokazu Nagai and Youji Miyamoto : Prevalence and imaging characteristics of palatine tonsilloliths evaluated on 2244 pairs of panoramic radiographs and CT images., Clinical Oral Investigations, Vol.21, No.1, 85-91, 2017. (Summary) Palatine tonsilloliths incidentally detected on diagnostic imaging should be differentiated from pathologic calcifications to enable correct diagnosis and treatment. The aim of this study is to clarify the prevalence and imaging characteristics of palatine tonsilloliths on panoramic radiographs. We retrospectively reviewed 2244 individuals who underwent pairs of consecutive panoramic radiography and computed tomography (CT) of the head and neck region. The imaging characteristics of palatine tonsilloliths on panoramic radiography were compared with the findings from CT, which was considered the gold standard. Tonsilloliths were detected in 300 (13.4 %) and 914 (40.7 %) of the 2244 individuals on panoramic radiographs and CT, respectively. On panoramic radiographs, tonsilloliths were superimposed over the ramus of the mandible at the level coincident with and inferior to the soft palate in 176 (7.8 %) and 90 (4.0 %) individuals, respectively. Tonsilloliths were also superimposed over the surrounding soft tissue inferior to the body of the mandible, postero-inferior to the angle of the mandible, and posterior to the ramus of the mandible in 33 (1.5 %), 26 (1.2 %), and 28 (1.3 %) individuals, respectively. A significant correlation was observed between the detectability on panoramic radiographs and the size (Spearman r = 1.000) and number (Spearman r = 0.991) of tonsilloliths, as revealed by CT images. The present results suggest that tonsilloliths are commonly detected on panoramic radiographs. Furthermore, they can be superimposed on both the mandible and the surrounding soft tissue. Clinicians should include tonsilloliths among the differential diagnoses when calcified bodies are detected on panoramic radiographs. (Tokushima University Institutional Repository) ● Metadata: 113566 (Link to Publication Site) ● Publication site (DOI): 10.1007/s00784-016-1752-0 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 26892471 ● Search Scopus @ Elsevier (PMID): 26892471 ● Search Scopus @ Elsevier (DOI): 10.1007/s00784-016-1752-0 (Tokushima University Institutional Repository: 113566, DOI: 10.1007/s00784-016-1752-0, PubMed: 26892471)
46.	Takaharu Kudoh, Hitoshi Ikushima, Keiko Kudoh, Shunsuke Furutani, Takashi Kawanaka, Akiko Kubo, Natsumi Takamaru, Tetsuya Tamatani and Youji Miyamoto : Effectiveness of Newly Developed Water-Equivalent Mouthpiece during External Beam Radiotherapy for Oral Cancer, Ann Carcinog, Vol.2, No.1, 2017. (Tokushima University Institutional Repository) ● Metadata: 113606 (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1570009752882329984 (Tokushima University Institutional Repository: 113606, CiNii: 1570009752882329984)
47.	Keiko Kudoh, Takaharu Kudoh, K Tsuru and Youji Miyamoto : A case of tophaceous pseudogout of the temporomandibular joint extending to the base of the skull, International Journal of Oral and Maxillofacial Surgery, Vol.46, No.3, 355-359, 2016. (Summary) A case of tophaceous pseudogout (i.e., calcium pyrophosphate dihydrate (CPPD) crystal deposition disease) in the temporomandibular joint (TMJ), extending to the base of the skull, is reported. A 38-year-old man was referred to the hospital with mild pain in the right chin and tip of the tongue. Panoramic radiography showed a large calcified mass around the right TMJ. Computed tomography imaging revealed a large, granular, calcified mass surrounding the right condylar head and extending to the base of the skull. The mass was clinically and radiographically suspected to be a pseudogout lesion. A biopsy specimen was collected under general anaesthesia to confirm the diagnosis. On histology, the mass was found to contain deposits of numerous rod-shaped and rhomboid crystals, which suggested tophaceous pseudogout. The deposits were identified as CPPD crystal deposition, based on analysis by X-ray diffraction and Fourier transform infrared spectroscopy. These two crystallography methods were useful in confirming the diagnosis of CPPD crystal deposition disease in the TMJ. (Keyword) Adult / Biopsy / Chondrocalcinosis / Diagnosis, Differential / Humans / Male / Radiography, Panoramic / Spectroscopy, Fourier Transform Infrared / Temporomandibular Joint Disorders / Tomography, X-Ray Computed / X-ray diffraction (Tokushima University Institutional Repository) ● Metadata: 112123 (Link to Publication Site) ● Publication site (DOI): 10.1016/j.ijom.2016.08.018 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 27641810 ● Summary page in Scopus @ Elsevier: 2-s2.0-84994787635 (Tokushima University Institutional Repository: 112123, DOI: 10.1016/j.ijom.2016.08.018, PubMed: 27641810, Elsevier: Scopus)
48.	Yoshiko Yamamura, Kenji Fujisawa, 鎌田久美子, Natsumi Takamaru, Keiko Kudoh, Go Ohe, Takaharu Kudoh, Akira Takahashi, Tetsuya Tamatani, Hirokazu Nagai and Youji Miyamoto : 口腔がん患者の歯科疾患罹患状況, 日本歯科人間ドック学会誌, Vol.11, No.1, 29-32, 2016.
49.	Kenji Fujisawa, Go Ohe, Hirokazu Nagai, Susumu Abe and Youji Miyamoto : A Retrospective Clinical Evaluation of the Survival of Dental Implants in Combination with Sinus Floor Elevation at 3 Years, Journal of Japanese Society of Oral Implantology, Vol.29, No.3, 22-27, 2016. (Summary) <p>The purpose of this study was to evaluate the risk factors for the loss of implants with sinus floor elevation. We statistically carried out a clinical examination on 49 cases, 80 implants at 3 years after the fitting of implant-anchored fixed prostheses.<br/>The results are summarized as follows:<br/>1. Two implants failed in 80 implants, indicating survival rates of 97.5%.<br/>2. There was no statistically significant difference between implant placement timing, initial bone height, sinus membrane thickness, type, diameter, primary stability of implants and graft materials used for sinus floor elevation.<br/>3. The length of implant affected the survival of implants used for sinus floor elevation.</p> (Keyword) sinus floor elevation / lateral window technique / length of implant (Link to Publication Site) ● Publication site (DOI): 10.11237/jsoi.29.180 (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1390001205511023104 ● Search Scopus @ Elsevier (DOI): 10.11237/jsoi.29.180 (DOI: 10.11237/jsoi.29.180, CiNii: 1390001205511023104)
50.	Kanae Hara, Kenji Fujisawa, Hirokazu Nagai, Natsumi Takamaru, Go Ohe, Kanji Tsuru, Kunio Ishikawa and Youji Miyamoto : Fabrication and Physical Evaluation of Gelatin-Coated Carbonate Apatite Foam, Materials, Vol.9, No.9, 711, 2016. (Summary) Carbonate apatite (CO3Ap) foam has gained much attention in recent years because of its ability to rapidly replace bone. However, its mechanical strength is extremely low for clinical use. In this study, to understand the potential of gelatin-reinforced CO3Ap foam for bone replacement, CO3Ap foam was reinforced with gelatin and the resulting physical characteristics were evaluated. The mechanical strength increased significantly with the gelatin reinforcement. The compressive strength of gelatin-free CO3Ap foam was 74 kPa whereas that of the gelatin-reinforced CO3Ap foam, fabricated using 30 mass % gelatin solution, was approximately 3 MPa. Heat treatment for crosslinking gelatin had little effect on the mechanical strength of the foam. The gelatin-reinforced foam did not maintain its shape when immersed in a saline solution as this promoted swelling of the gelatin; however, in the same conditions, the heat-treated gelatin-reinforced foam proved to be stable. It is concluded, therefore, that heat treatment is the key to the fabrication of stable gelatin-reinforced CO3Ap foam. (Tokushima University Institutional Repository) ● Metadata: 113607 (Link to Publication Site) ● Publication site (DOI): 10.3390/ma9090711 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 28773832 ● Summary page in Scopus @ Elsevier: 2-s2.0-84988983311 (Tokushima University Institutional Repository: 113607, DOI: 10.3390/ma9090711, PubMed: 28773832, Elsevier: Scopus)
51.	Chieko Sugawara, Akira Takahashi, Fumiaki Kawano, Yasusei Kudo, Naozumi Ishimaru and Youji Miyamoto : Intraoral Ultrasonography of Tongue Mass Lesions, Dento Maxillo Facial Radiology, Vol.45, No.5, 20150362, 2016. (Summary) To demonstrate the usefulness of intraoral ultrasonography (IOUS) for tongue mass lesions, we analyzed surgery cases excluding squamous-cell carcinoma and leukoplakia and compared IOUS and pathological findings. We used the hospital information system and Radiology Information System to evaluate the IOUS and pathological findings of patients who underwent surgeries for tongue masses in the past 11 years. Surgeries for the tongues were performed in 268 cases. Imaging examinations were carried out in 52 (19.4%) cases including 42 (15.7%) cases by IOUS. The pathological results of the surgeries were as follows: 36 cases were inflammatory lesions, 74 cases were tumours, 131 cases were hyperplasia, 8 cases were cystic lesions and 19 cases were other miscellaneous lesions. On the other hand, the number of patients who received IOUS in the same period was 87, and 42 of them had surgeries. In 32 out of the 42 (76.2%) cases, pre-operative IOUS features matched with pathological results. Most of the haemangiomas and lipomas could be diagnosed by IOUS alone. IOUS of the tongue revealed the nature of the lesions including the border, size, location, depth, the presence or absence of a capsule and the internal structure including vascularity of the mass. The ultrasonographic findings well reflected the histological findings. IOUS is a simple and useful technique that provides additional information beyond inspection, clarifying the internal structure, blood flow and relationships with the adjacent tissues. In this article, we indicated 11 representative cases (fibrous polyp, haemangioma, pyogenic granuloma, lipoma, liposarcoma, chondroma, lymphangioma, schwannoma, neurofibroma, pleomorphic adenoma and amyloidosis) to show the usefulness of IOUS. (Keyword) ultrasound (Tokushima University Institutional Repository) ● Metadata: 111906 (Link to Publication Site) ● Publication site (DOI): 10.1259/dmfr.20150362 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 26915405 ● Search Scopus @ Elsevier (PMID): 26915405 ● Search Scopus @ Elsevier (DOI): 10.1259/dmfr.20150362 (Tokushima University Institutional Repository: 111906, DOI: 10.1259/dmfr.20150362, PubMed: 26915405)
52.	Maki Hosoki, Keisuke Nishigawa, Youji Miyamoto, Go Ohe and Yoshizo Matsuka : Allergic contact dermatitis caused by titanium screws and dental implants, Journal of Prosthodontic Research, Vol.60, No.3, 213-219, 2016. (Summary) Titanium has been considered to be a non-allergenic material. However, several studies have reported cases of metal allergy caused by titanium-containing materials. We describe a 69-year-old male for whom significant pathologic findings around dental implants had never been observed. He exhibited allergic symptoms (eczema) after orthopedic surgery. The titanium screws used in the orthopedic surgery that he underwent were removed 1 year later, but the eczema remained. After removal of dental implants, the eczema disappeared completely. Titanium is used not only for medical applications such as plastic surgery and/or dental implants, but also for paints, white pigments, photocatalysts, and various types of everyday goods. Most of the usage of titanium is in the form of titanium dioxide. This rapid expansion of titanium-containing products has increased percutaneous and permucosal exposure of titanium to the population. In general, allergic risk of titanium material is smaller than that of other metal materials. However, we suggest that pre-implant patients should be asked about a history of hypersensitivity reactions to metals, and patch testing should be recommended to patients who have experienced such reactions. (Keyword) Aged / Bone Screws / Dental Implants / Dental Materials / Dermatitis, Allergic Contact / Device Removal / Humans / Male / Orthopedic Procedures / titanium (Tokushima University Institutional Repository) ● Metadata: 111970 (Link to Publication Site) ● Publication site (DOI): 10.1016/j.jpor.2015.12.004 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 26774509 ● CiNii @ National Institute of Informatics (CRID): 1390282680276696576 ● Summary page in Scopus @ Elsevier: 2-s2.0-84953449555 (Tokushima University Institutional Repository: 111970, DOI: 10.1016/j.jpor.2015.12.004, PubMed: 26774509, CiNii: 1390282680276696576, Elsevier: Scopus)
53.	Natsumi Takamaru, Hirokazu Nagai, Go Ohe, Tetsuya Tamatani, Kaori Sumida, Seiichiro Kitamura and Youji Miyamoto : Measurement of the zygomatic bone and pilot hole technique for safer insertion of zygomaticus implants, International Journal of Oral and Maxillofacial Surgery, Vol.45, No.1, 104-109, 2016. (Summary) The zygomaticus implant was developed for patients with severe bone resorption of the posterior maxilla. These may eliminate or minimize the need for bone grafting. Although the zygomaticus implant has shown a remarkable success rate in this difficult-to-treat patient population, the method requires an advanced surgical technique and carries an increased risk of complications. There have been few anatomical studies on the zygomatic bone in relation to the insertion of zygomaticus implants. The height and thickness of the zygomatic bone for the insertion were measured in this study. The thickness at the 90° angle point, where the upper margin of the zygomatic arch and the temporal margin of the frontal process of the zygomatic bone intersect and where the apex of the implant penetrates, was found to be 1.8±0.4 mm; this gradually increased inferiorly and anteriorly. Thus, the penetration point of the apex of the zygomaticus implant should be located more inferoanterior to the 90° angle point, as the thickness in this region is thinner than the diameter of the implant. Based on the results of this study, a newer and safer insertion method for the zygomaticus implant using a drill guide is proposed. (Tokushima University Institutional Repository) ● Metadata: 114011 (Link to Publication Site) ● Publication site (DOI): 10.1016/j.ijom.2015.07.015 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 26395065 ● Summary page in Scopus @ Elsevier: 2-s2.0-84952870149 (Tokushima University Institutional Repository: 114011, DOI: 10.1016/j.ijom.2015.07.015, PubMed: 26395065, Elsevier: Scopus)
54.	Takeshi Yamamoto, Kenji Fujisawa, Go Ohe, Hirokazu Nagai and Youji Miyamoto : インプラントの表面性状がオッセオインテグレーション喪失に及ぼす影響:滑面(機械加工面)と粗面(陽極酸化面)インプラント体の比較, Journal of Japanese Society of Oral Implantology, Vol.28, No.3, 18-25, 2015. (Link to Publication Site) ● Publication site (DOI): 10.11237/jsoi.28.318 (Link to Search Site for Scientific Articles) ● Search Scopus @ Elsevier (DOI): 10.11237/jsoi.28.318 (DOI: 10.11237/jsoi.28.318)
55.	Kenji Fujisawa, Go Ohe, Hirokazu Nagai, Susumu Abe and Youji Miyamoto : インプラント体の表面性状の違いが周囲骨吸収に及ぼす影響:埋入後5年経過時の同一患者の隣接するインプラント体により比較, Journal of Japanese Society of Oral Implantology, Vol.28, No.3, 12-17, 2015. (Link to Publication Site) ● Publication site (DOI): 10.11237/jsoi.28.312 (Link to Search Site for Scientific Articles) ● Search Scopus @ Elsevier (DOI): 10.11237/jsoi.28.312 (DOI: 10.11237/jsoi.28.312)
56.	Hirokazu Nagai, Masako Fujioka-Kobayashi, Kenji Fujisawa, Go Ohe, Natsumi Takamaru, Kanae Hara, Daisuke Uchida, Tetsuya Tamatani, Kunio Ishikawa and Youji Miyamoto : Effects of low crystalline carbonate apatite on proliferation and osteoblastic differentiation of human bone marrow cells, Journal of Materials Science. Materials in Medicine, Vol.26, No.2, 99, 2015. (Summary) Carbonated apatite (CO3Ap) is the inorganic component of bone. We have proposed a new method for the fabrication of CO3Ap blocks based on a dissolution-precipitation method using a synthetic precursor. The aim of this study is to examine the effects of low crystalline CO3Ap on initial cell attachment, proliferation and osteoblastic differentiation of human bone marrow cells (hBMCs) using sintered hydroxyapatite and tissue culture plates as controls. Initial cell attachment and proliferation were assessed with a MTT assay. Expression of osteoblastic markers was examined by reverse transcription-polymerase chain reaction. XRD and FT-IR results showed formation of B-type carbonate apatite with lower crystallinity. No difference was observed for initial cell attachment between HAp and CO3Ap discs. hBMSC attached more significantly on tissue culture plate than on HAp and CO3Ap discs. The number of cells on HAp was higher than that on CO3Ap until day 7, after which the number of cells was similar. hBMSC proliferated more significantly on tissue culture plate than on HAp and CO3Ap discs. In contrast, hBMCs incubated on CO3Ap demonstrated much higher expression of osteoblastic markers of differentiation, such as type I collagen, alkaline phosphatase, osteopontin and osteocalcin, than hBMCs on HAp. On the tissue culture plate, they were not any change throughout the culture period. These results demonstrated that low crystalline CO3Ap exhibit higher osteoinductivity than HAp. (Keyword) Alkaline Phosphatase / Apatites / Biomarkers / Bone Marrow Cells / Bone Substitutes / Cell Adhesion / Cell Culture Techniques / cell differentiation / Cell Proliferation / Collagen Type I / crystallization / Durapatite / Humans / Materials Testing / Osteoblasts / Osteocalcin / Osteogenesis / osteopontin / Spectroscopy, Fourier Transform Infrared / X-ray diffraction (Link to Publication Site) ● Publication site (DOI): 10.1007/s10856-015-5431-5 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 25655499 ● Summary page in Scopus @ Elsevier: 2-s2.0-84922324403 (DOI: 10.1007/s10856-015-5431-5, PubMed: 25655499, Elsevier: Scopus)
57.	Chieko Sugawara, Akira Takahashi, Fumiaki Kawano, Takaharu Kudoh, Akiko Yamada, Naozumi Ishimaru, Hara Kanae and Youji Miyamoto : Neuroendocrine tumor in the mandible: a case report with imaging and histopathologic findings, Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology, Vol.119, No.1, e41-e48, 2015. (Summary) Neuroendocrine tumors (NETs) arise from neuroendocrine cells and are mostly observed in the gastrointestinal tract, pancreas, and lungs. NETs in the oral and maxillofacial region are extremely rare. We report a case of a 59-year-old woman with an NET in the mandible. The patient did not show any symptoms except for remarkable swelling and bleeding. The lesion appeared as a radiolucent honeycomb abnormality with bone destruction on panoramic radiography. The histopathologic diagnosis following a biopsy was NET. Contrast-enhanced computed tomography (CT), (18)F-fluorodeoxyglucose positron emission computed tomography ((18)F-FDG PET/CT), and adrenal scintigraphy-labeled meta-iodobenylguanidine were the modalities added to identify the primary site. Multiple lesions were confirmed in the gastrointestinal tract. Endoscopy was performed to identify the lesions, and several lesions were observed protruding from the mucous membranes. However, the endoscopy specimens did not yield an accurate diagnosis because adequate samples were not acquired. Blood and urine tests revealed no functional activity caused by the tumors. Although the origin was not histopathologically confirmed with endoscopy, this patient was situationally diagnosed with nonfunctional NET originating from the duodenum, as demonstrated by the metastases in the mandible. (Keyword) neuroendocrine tumor / neuroendocrine carcinoma / oral cavity / synaptophysin / chromogranin A (Link to Publication Site) ● Publication site (DOI): 10.1016/j.oooo.2014.09.024 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 25459356 ● Summary page in Scopus @ Elsevier: 2-s2.0-84915767535 (DOI: 10.1016/j.oooo.2014.09.024, PubMed: 25459356, Elsevier: Scopus)
58.	Makoto Kinouchi, Daisuke Uchida, Nobuyuki Kuribayashi, Tetsuya Tamatani, Hirokazu Nagai and Youji Miyamoto : Involvement of miR-518c-5p to Growth and Metastasis in Oral Cancer, PLoS ONE, Vol.9, No.12, e115936, 2014. (Summary) We have previously demonstrated that a stromal cell-derived factor-1 (SDF-1; CXCL12)/CXCR4 system is involved in the establishment of metastasis in oral cancer. Recently, small non coding RNAs, microRNAs (miRNAs) have been shown to be involved in the metastatic process of several types of cancers. However, the miRNAs that contribute to metastases induced by the SDF-1/CXCR4 system in oral cancer are largely unknown. In this study, we examined the metastasis-related miRNAs induced by the SDF-1/CXCR4 system using B88-SDF-1 oral cancer cells, which exhibit functional CXCR4 and distant metastatic potential in vivo. Through miRNA microarray analysis, we identified the upregulation of miR-518c-5p in B88-SDF-1 cells, and confirmed the induction by real-time PCR analysis. Although an LNA-based miR-518c-5p inhibitor did not affect cell growth of B88-SDF-1 cells, it did significantly inhibit the migration of the cells. Next, we transfected a miR-518c expression vector into parental B88 cells and CAL27 oral cancer cells and isolated stable transfectants, B88-518c and CAL27-518c cells, respectively. The anchorage-dependent and -independent growth of miR-518c transfectants was significantly enhanced compared with the growth of mock cells. Moreover, we detected the enhanced migration of these cells. The LNA-based miR-518c-5p inhibitor significantly impaired the enhanced cell growth and migration of miR-518c transfectants, indicating that these phenomena were mainly dependent on the expression of miR-518c-5p. Next, we examined the function of miR-518c-5p in vivo. miR-518c transfectants or mock transfectants were inoculated into the masseter muscle or the blood vessels of nude mice. Tumor volume, lymph nodes metastasis, and lung metastasis were significantly increased in the mice inoculated with the miR-518c transfectants. These results indicated that miR-518c-5p regulates the growth and metastasis of oral cancer as a downstream target of the SDF-1/CXCR4 system. (Tokushima University Institutional Repository) ● Metadata: 109400 (Link to Publication Site) ● Publication site (DOI): 10.1371/journal.pone.0115936 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 25536052 ● Summary page in Scopus @ Elsevier: 2-s2.0-84919809244 (Tokushima University Institutional Repository: 109400, DOI: 10.1371/journal.pone.0115936, PubMed: 25536052, Elsevier: Scopus)
59.	Akira Takahashi, Chieko Sugawara, Takaharu Kudoh, Daisuke Uchida, Tetsuya Tamatani, Hirokazu Nagai and Youji Miyamoto : Prevalence and Imaging Characteristics of Palatine Tonsilloloths Detected by CT in 2,873 Consecutive Patients, The Scientific World Journal, 2014. (Tokushima University Institutional Repository) ● Metadata: 113567 (Link to Publication Site) ● Publication site (DOI): 10.1155/2014/940960 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 25389536 ● Summary page in Scopus @ Elsevier: 2-s2.0-84908347485 (Tokushima University Institutional Repository: 113567, DOI: 10.1155/2014/940960, PubMed: 25389536, Elsevier: Scopus)
60.	Yoshiro Abe, Ichiro Hashimoto, Shinji Matsuo, Keiichi Goishi, Keisuke Kashiwagi, Hirokazu Nagai, Youji Miyamoto and Hideki Nakanishi : Three-dimensional sodium chloride (NaCI) model for simulated mandibular reconstruction surgery : a new environmentally friendly material, The Journal of Medical Investigation : JMI, Vol.61, No.3,4, 318-324, 2014. (Summary) Mandibular reconstruction using a fibular graft is a difficult procedure that requires technical expertise to enable adequate occlusal function and restore an aesthetic appearance. Here we used three-dimensional (3D) sodium chloride (NaCl) models for simulated mandibular reconstruction surgery. This study aimed to reveal the accuracy of mandibular reconstruction with fibular grafts using this model. Mandibular reconstructions using 3D NaCl models were performed in 5 cases. The maxilla, mandible, and fibular models were developed using computed tomography (CT) data. We performed preoperative cutting and simulation surgery using this model. Angles between the body of the corpus and symphysis were measured from the axial view (n = 4). Angles between the ramus and the body of the corpus were measured from the lateral and axial views (n = 6). These angles were measured on simulated models and postoperative CT images were compared. Differences between the angles measured on the simulated models and postoperative CT images were 0-5° (mean, 1.9°). We were able to reproduce the neomandibles with precise osteotomies using the 3D NaCl models. We believe that simulated mandibular reconstruction surgery using this model might help reduce the number of intraoperative neomandibular segment adjustments. (Tokushima University Institutional Repository) ● Metadata: 109579 (Link to Publication Site) ● Publication site (DOI): 10.2152/jmi.61.318 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 25264050 ● Summary page in Scopus @ Elsevier: 2-s2.0-84907501630 (Tokushima University Institutional Repository: 109579, DOI: 10.2152/jmi.61.318, PubMed: 25264050, Elsevier: Scopus)
61.	Hirokazu Nagai, Masako Fujioka-Kobayashi, Go Ohe, Kanae Hara, Natsumi Takamaru, Daisuke Uchida, Tetsuya Tamatani, Kenji Fujisawa and Youji Miyamoto : Antitumour effect of valproic acid against salivary gland cancer in vitro and in vivo, Oncology Reports, Vol.31, No.3, 1453-1458, 2014. (Summary) Salivary gland cancer (SGC) has a comparatively poor prognosis and is prone to frequent recurrence and metastases. Therefore, the development of more effective chemotherapy against SGC is desirable. The aim of the present study was to investigate the antitumour effects of valproic acid (VPA) against SGC in vitro and in vivo. Two human SGC cell lines (HSY and HSG cells) were used in the present study. The effects of VPA on the proliferation of SGC cells in vitro were assessed by MTT assay. Cancer cells treated with VPA were subjected to cell cycle analysis by flow cytometry. In addition, the expression levels of p21 and p27 were examined by real-time RT-PCR to identify the mechanisms of the antitumour effect of VPA on SGC. The effects of VPA on cancer growth in vivo were evaluated in a xenograft model. VPA inhibited the proliferation of SGC cells in a dose-dependent manner in vitro. Degenerated cancer cells were observed at high concentrations of VPA. In the cell cycle analysis, VPA induced cell-growth inhibition and G1 arrest of cell cycle progression in both cancer cell lines in a time- and dose-dependent manner. VPA markedly upregulated the mRNA expression levels of both p21 and p27 in both SGC cell lines in a time-dependent manner. In the xenograft model experiment, VPA treatment markedly inhibited the growth of salivary gland tumours when compared with the growth of the untreated controls. VPA may be a valuable drug in the development of better therapeutic regimens for SGC. (Keyword) Adenocarcinoma / Animals / Antineoplastic Agents / Cell Line, Tumor / Cell Survival / Cyclin-Dependent Kinase Inhibitor p21 / Cyclin-Dependent Kinase Inhibitor p27 / Gene Expression / Humans / Mice / Mice, Inbred BALB C / Mice, Nude / Salivary Gland Neoplasms / Valproic Acid / Xenograft Model Antitumor Assays (Tokushima University Institutional Repository) ● Metadata: 113603 (Link to Publication Site) ● Publication site (DOI): 10.3892/or.2013.2959 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 24398788 ● Summary page in Scopus @ Elsevier: 2-s2.0-84896709497 (Tokushima University Institutional Repository: 113603, DOI: 10.3892/or.2013.2959, PubMed: 24398788, Elsevier: Scopus)
62.	Shinji Fujihara, Tatsuya Nakamura, Kumiko Nagata, Tomoko Kataura, Chieko Shiota, Shinya Horiuchi, Shingo Kuroda, Takuya Seike, Ichiro Hashimoto, Hideki Nakanishi, Hirokazu Nagai, Youji Miyamoto and Eiji Tanaka : 顎顔面領域における骨治癒に対する低出力超音波パルス照射の使用経験, Shikoku Dental Research, Vol.26, No.2, 41-47, 2014. (Tokushima University Institutional Repository) ● Metadata: 109843 (Tokushima University Institutional Repository: 109843)
63.	Kenji Fujisawa, Go Ohe, Daisuke Uchida, Tetsuya Tamatani, Hirokazu Nagai and Youji Miyamoto : A Clinical Study on the Usefulness of Short Implants, Journal of Japanese Society of Oral Implantology, Vol.26, No.4, 26-33, 2013. (Summary) The purpose of this study was to determine whether clinical success can be achieved with Brånemark system short implants (Nobel Biocare) three years after the placement of implants. <br/>One hundred and thirteen short implants (10 mm) were installed:42 implants with smooth surfaces and 71 implants with rough surfaces. Twenty-two implants were installed in the maxilla, and 91 implants in the mandible. All implants were submerged. A chi-square test was used to evaluate the significance of implant loss of short implants with implants longer than 10 mm.<br/>There was no significant difference in the failure rates between short implants and implants longer than 10 mm. Among smooth surface implants, the failure rate of short implants was significantly higher than that of implants longer than 10 mm, but among rough surface implants, no significant difference in the failure rates was observed between short implants and implants longer than 10 mm. These results demonstrated that short implants with rough surfaces were as useful as implants longer than 10 mm. (Keyword) short implants / implant surface roughness (Link to Publication Site) ● Publication site (DOI): 10.11237/jsoi.26.676 (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1390001205506584064 ● Search Scopus @ Elsevier (DOI): 10.11237/jsoi.26.676 (DOI: 10.11237/jsoi.26.676, CiNii: 1390001205506584064)
64.	Nobuyuki Kuribayashi, Daisuke Uchida, Makoto Kinouchi, Natsumi Takamaru, Tetsuya Tamatani, Hirokazu Nagai and Youji Miyamoto : The Role of Metabotropic Glutamate Receptor 5 on the Stromal Cell-Derived Factor-1/CXCR4 System in Oral Cancer, PLoS ONE, Vol.8, No.11, e80773, 2013. (Summary) We have demonstrated that blocking CXCR4 may be a potent anti-metastatic therapy for CXCR4-related oral cancer. However, as CXCR4 antagonists are currently in clinical use to induce the mobilization of hematopoietic stem cells, continuous administration as an inhibitor for the metastasis may lead to persistent leukocytosis. In this study, we investigated the novel therapeutic downstream target(s) of the SDF-1/CXCR4 system, using B88-SDF-1 cells, which have an autocrine SDF-1/CXCR4 system and exhibit distant metastatic potential in vivo. Microarray analysis revealed that 418 genes were upregulated in B88-SDF-1 cells. We identified a gene that is highly upregulated in B88-SDF-1 cells, metabotropic glutamate receptor 5 (mGluR5), which was downregulated following treatment with 1,1' -[1,4-Phenylenebis(methylene)]bis-1,4,8,11-tetraazacyclotetradecane octahydrochloride (AMD3100), a CXCR4 antagonist. The upregulation of mGluR5 mRNA in the SDF-1/CXCR4 system was predominately regulated by the Ras-extracellular signal-regulated kinase (ERK)1/2 pathway. Additionally, the growth of B88-SDF-1 cells was not affected by the mGluR5 agonist (S)-3,5-DHPG (DHPG) or the mGluR5 antagonists 2-Methyl-6-(phenylethynyl)pyridine (MPEP) and 3-((2-Methyl-1,3-thiazol-4-yl)ethynyl)pyridine (MTEP). However, we observed that DHPG promoted B88-SDF-1 cell migration, whereas both MPEP and MTEP inhibited B88-SDF-1 cell migration. To assess drug toxicity, the antagonists were intraperitoneally injected into immunocompetent mice for 4 weeks. Mice injected with MPEP (5 mg/kg) and MTEP (5 mg/kg) did not exhibit any side effects, such as hematotoxicity, allergic reactions or weight loss. The administration of antagonists significantly inhibited the metastasis of B88-SDF-1 cells to the lungs of nude mice. These results suggest that blocking mGluR5 with antagonists such as MPEP and MTEP could prevent metastasis in CXCR4-related oral cancer without causing side effects. (Link to Publication Site) ● Publication site (DOI): 10.1371/journal.pone.0080773 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 24236200 ● Search Scopus @ Elsevier (PMID): 24236200 ● Search Scopus @ Elsevier (DOI): 10.1371/journal.pone.0080773 (DOI: 10.1371/journal.pone.0080773, PubMed: 24236200)
65.	Go Ohe, Akiko Sasai, Daisuke Uchida, Tetsuya Tamatani, Hirokazu Nagai and Youji Miyamoto : Effect of soluble factors derived from oral cancer cells on the production of interferon-γ from peripheral blood mononuclear cells following stimulation with OK-432, Oncology Reports, Vol.30, No.2, 945-951, 2013. (Summary) The streptococcal antitumor agent OK-432 is commonly used as an immunopotentiator for immunotherapy in various types of malignant tumors including oral cancer. It has been demonstrated that OK-432 elicits an antitumor effect by stimulating immunocompetent cells, thereby inducing multiple cytokines including interferon (IFN)-γ, interleukin (IL)-2 and IL-12. Serum concentrations of IFN-γ in patients with oral cancer were examined 24 h after administration of OK-432. Serum concentrations of IFN-γ in patients with advanced cancer were significantly lower than those in patients with early cancer. These results suggested that some soluble factors produced by cancer cells may inhibit IFN-γ production with OK-432. Thus, in the present study, an in vitro simulation model was established for the immune status of patients with oral cancer by adding conditioned medium (CM) derived from oral cancer cell lines into a culture of peripheral blood mononuclear cells (PBMCs) derived from a healthy volunteer. We investigated whether soluble factors derived from oral cancer cells affected IFN-γ production from PBMCs following stimulation with OK-432. PBMCs stimulated with OK-432 produced a large amount of IFN-γ; however, both IFN-γ production and cytotoxic activity from PBMCs induced by OK-432 were inhibited by the addition of CM in a dose-dependent manner. In order to examine these inhibitory effects against IFN-γ production, the contribution of inhibitory cytokines such as IL-4, IL-6, IL-10, transforming growth factor-β and vascular endothelial growth factor was investigated. However, neutralization of these inhibitory cytokines did not recover IFN-γ production inhibited by CM. These results indicated that unknown molecules may inhibit IFN-γ production from PBMCs following stimulation with OK-432. (Tokushima University Institutional Repository) ● Metadata: 113600 (Link to Publication Site) ● Publication site (DOI): 10.3892/or.2013.2480 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 23685791 ● Search Scopus @ Elsevier (PMID): 23685791 ● Search Scopus @ Elsevier (DOI): 10.3892/or.2013.2480 (Tokushima University Institutional Repository: 113600, DOI: 10.3892/or.2013.2480, PubMed: 23685791)
66.	Tetsuya Tamatani, Natsumi Takamaru, Kanae Hara, Makoto Kinouchi, Nobuyuki Kuribayashi, Go Ohe, Daisuke Uchida, Kenji Fujisawa, Hirokazu Nagai and Youji Miyamoto : Bortezomib-enhanced radiosensitization through the suppression of radiation-induced nuclear factor B activity in human oral cancer cells., International Journal of Oncology, Vol.42, No.3, 935-944, 2013. (Summary) Oral cancer cells have a significantly augmented nuclear factor-κB (NF-κB) activity and the inhibition of this activity suppresses tumor growth. Bortezomib is a proteasome inhibitor and a drug used for molecular-targeted therapy (targets NF-κB). In this study, we investigated whether bortezomib would be effective as an inhibitor of proliferation and a radiosensitizer for the treatment of oral cancer. We demonstrate that bortezomib inhibits NF-κB activity and cell proliferation. The combined treatment with bortezomib and radiation (RT) suppressed NF-κB activity and cell growth in vitro and in vivo compared with RT treatment alone. To investigate the mechanisms by which bortezomib suppresses tumor growth, the expression of signaling molecules downstream of NF-κB were examined by ELISA. The combined treatment significantly inhibited the radiation-induced production of angiogenic factors and decreased the number of blood vessels in the tumor tissues. Although the expression of anti-apoptotic proteins was upregulated by RT, bortezomib downregulated the RT-induced expression of these proteins. Moreover, the expression of cleaved poly(ADP-ribose) polymerase in vitro and in vivo was enhanced by bortezomib, indicating that bortezomib inhibits tumor growth by inducing apoptosis. This study clearly demonstrates that bortezomib significantly inhibits tumor growth and that the combined treatment with bortezomib and RT results in a significant inhibition of tumor growth. The mechanisms underlying the inhibition of tumor growth by bortezomib include the suppression of angiogenesis and the induction of apoptosis. A novel molecular targeting therapy including bortezomib may be effective in the treatment of oral cancer by suppressing NF-κB activity. (Keyword) Animals / Antineoplastic Agents / Apoptosis / Boronic Acids / Cell Line, Tumor / Cell Proliferation / Female / Humans / I-kappa B Proteins / Interleukin-6 / Interleukin-8 / Mice / Mice, Inbred BALB C / Mice, Nude / Mouth Neoplasms / NF-kappa B / Neoplasm Transplantation / Neovascularization, Pathologic / Poly(ADP-ribose) Polymerases / Pyrazines / Radiation-Sensitizing Agents / Transcription Factor RelA / Vascular Endothelial Growth Factor A / Xenograft Model Antitumor Assays (Tokushima University Institutional Repository) ● Metadata: 113601 (Link to Publication Site) ● Publication site (DOI): 10.3892/ijo.2013.1786 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 23340716 ● Search Scopus @ Elsevier (PMID): 23340716 ● Search Scopus @ Elsevier (DOI): 10.3892/ijo.2013.1786 (Tokushima University Institutional Repository: 113601, DOI: 10.3892/ijo.2013.1786, PubMed: 23340716)
67.	Daisuke Uchida, Nobuyuki Kuribayashi, Go Ohe, Tetsuya Tamatani, Hirokazu Nagai and Youji Miyamoto : Expression and function of CXCR4 in human salivary gland cancers, Clinical & Experimental Metastasis, Vol.30, No.2, 133-142, 2013. (Summary) Salivary gland cancers (SGCs) frequently metastasize to cervical lymph nodes and distant organs. Currently, the mechanisms responsible for the metastatic behavior of SGC cells are not fully understood. We previously demonstrated that the stromal cell-derived factor-1 (SDF-1; also known as CXCL12)/CXCR4 system is involved in the establishment of metastasis in oral squamous cell carcinoma. In the present study, we investigated the role of CXCR4 in the metastatic behavior of SGCs. We examined the expression of CXCR4 mRNA and protein in human SGC cell lines by quantitative RT-PCR and western blotting, respectively. The expression of CXCR4 mRNA and protein were frequently upregulated in 5 out of 6 SGC cell lines. Functional CXCR4 expression was demonstrated by the ability of these SGC cell lines to migrate toward an SDF-1 gradient. SDF-1 rapidly activated extracellular signal-regulated kinase (ERK)1/2 in SGC cell lines. Immunohistochemical analysis revealed that CXCR4 protein expression was detected in either the nucleus or cytoplasm of cancer cells in 16 out of 20 tissues of adenoid cystic carcinoma (ACC) and in 4 out of 6 tissues of mucoepidermoid carcinoma, which are representative of SGC. Furthermore, ACC cell lines exhibited dramatic metastasis to the lung following intravenous inoculation, whereas AMD3100, a CXCR4 antagonist, significantly inhibited lung metastasis of the cells, ameliorated body weight loss and improved the survival rate of tumor-bearing nude mice. These results indicate that CXCR4 expression contributes to the metastatic potential of SGCs. (Keyword) Animals / Blotting, Western / Carcinoma, Squamous Cell / Cell Adhesion / Cell Movement / Chemokine CXCL12 / Enzyme-Linked Immunosorbent Assay / Flow Cytometry / Heterocyclic Compounds / Humans / Immunoenzyme Techniques / Lung Neoplasms / Lymphatic Metastasis / Mice / Mice, Inbred BALB C / Mice, Nude / Mitogen-Activated Protein Kinase 3 / RNA, Messenger / Real-Time Polymerase Chain Reaction / Receptors, CXCR4 / Reverse Transcriptase Polymerase Chain Reaction / Salivary Gland Neoplasms / Tumor Cells, Cultured (Link to Publication Site) ● Publication site (DOI): 10.1007/s10585-012-9518-9 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 22847686 ● Summary page in Scopus @ Elsevier: 2-s2.0-84875066432 (DOI: 10.1007/s10585-012-9518-9, PubMed: 22847686, Elsevier: Scopus)
68.	Natsumi Takamaru, Daisuke Uchida, Go Ohe, Hirokazu Nagai, Naozumi Ishimaru and Youji Miyamoto : A case of giant cell epulis accompanied by bone formation in the premolar region of the mandible, Japanese Journal of Oral & Maxillofacial Surgery, Vol.58, No.11, 651-654, 2012. (Summary) Giant cell epulis (peripheral giant cell granuloma) is a granuloma consisting of a large number of multinucleated giant cells. Its incidence is high in Europe and the United States, but is very low in Japan. Giant cell epulis accompanied by bone formation is extremely rare in Japan. We report a case of giant cell epulis accompanied by bone formation. A 46-year-old woman visited our hospital because of a mass in the left mandibular molar region. There was a well-demarcated, pedunculated mass in the left mandibular molar region. The mass was excised under the clinical diagnosis of epulis. Histopathologically, the resected specimen consisted of spindle cells resembling fibroblasts and many multinucleated giant cells. Moreover, newly synthesized bone was observed in the center of the mass. The pathological diagnosis was a giant cell granuloma. Two years six months after the operation, there has been no evidence of recurrence. (Keyword) giant cell epulis(巨細胞エプーリス) / giant cell epulis(キョサイボウエプーリス) / bone formation(骨形成) / bone formation(ホネケイセイ) (Link to Publication Site) ● Publication site (DOI): 10.5794/jjoms.58.651 (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1390282681509153536 ● Search Scopus @ Elsevier (DOI): 10.5794/jjoms.58.651 (DOI: 10.5794/jjoms.58.651, CiNii: 1390282681509153536)
69.	Masako Fujioka-Kobayashi, Masato Ota, Asako Shimoda, Ken-ichi Nakahama, Kazunari Akiyoshi, Youji Miyamoto and Sachiko Iseki : Cholesteryl group- and acryloyl group-bearing pullulan nanogel to deliver BMP2 and FGF18 for bone tissue engineering., Biomaterials, Vol.33, No.30, 7613-7620, 2012. (Summary) To create a drug delivery system that allows the controlled release of proteins, such as growth factors, over a long-term period, cholesteryl group- and acryloyl group-bearing pullulan (CHPOA) nanogels were aggregated to form fast-degradable hydrogels (CHPOA/hydrogels) by cross-linking with thiol-bearing polyethylene glycol. The gold standard of clinical bone reconstruction therapy with a physiologically active material is treatment with recombinant human bone morphogenetic protein 2 (BMP2); however, this approach has limitations, such as inflammation, poor cost-efficiency, and varying interindividual susceptibility. In this study, two distinct growth factors, BMP2 and recombinant human fibroblast growth factor 18 (FGF18), were applied to a critical-size skull bone defect for bone repair by the CHPOA/hydrogel system. The CHPOA-FGF18/hydrogel displayed identical results to the control CHPOA-PBS/hydrogel, and the CHPOA-BMP2/hydrogel treatment imperfectly induced bone repair. By contrast, the CHPOA-FGF18 + BMP2/hydrogel treatment strongly enhanced and stabilized the BMP2-dependent bone repair, inducing osteoprogenitor cell infiltration inside and around the hydrogel. This report indicates that the CHPOA/hydrogel system can successfully deliver two different proteins to the bone defect to induce effective bone repair. The combination of the CHPOA/hydrogel system with the growth factors FGF18 and BMP2 might be a step towards efficient bone tissue engineering. (Keyword) Acrylates / Animals / Bone Morphogenetic Protein 2 / Bone Regeneration / Bone and Bones / Cell Lineage / cholesterol / Drug Delivery Systems / Fibroblast Growth Factors / Glucans / Humans / Mice / Mice, Inbred C57BL / Osteoblasts / Polyethylene Glycols / Polyethyleneimine / Recombinant Proteins / Rhodamines / tissue engineering / Tomography, X-Ray Computed / Transforming Growth Factor beta / Wound Healing (Link to Publication Site) ● Publication site (DOI): 10.1016/j.biomaterials.2012.06.075 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 22800537 ● Summary page in Scopus @ Elsevier: 2-s2.0-84864963987 (DOI: 10.1016/j.biomaterials.2012.06.075, PubMed: 22800537, Elsevier: Scopus)
70.	Chieko Sugawara, Akira Takahashi, Michiko Kubo, Hideki Otsuka, Naozumi Ishimaru, Youji Miyamoto and Eiichi Honda : Preoperative evaluation of patients with squamous cell carcinoma of the oral cavity: fluorine-18 fluorodeoxyglucose positron emission tomography/computed tomography and ultrasonography versus histopathology., Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology, Vol.114, No.4, 516-525, 2012. (Summary) PET/CT and US are complementary tools to evaluate preoperative patients. (Link to Publication Site) ● Publication site (DOI): 10.1016/j.oooo.2012.06.004 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 22986248 ● Search Scopus @ Elsevier (PMID): 22986248 ● Search Scopus @ Elsevier (DOI): 10.1016/j.oooo.2012.06.004 (DOI: 10.1016/j.oooo.2012.06.004, PubMed: 22986248)
71.	Tetsuya Tamatani, Tarannum Ferdous, Natsumi Takamaru, Kanae Hara, Makoto Kinouchi, Nobuyuki Kuribayashi, Go Ohe, Daisuke Uchida, Hirokazu Nagai, Kenji Fujisawa and Youji Miyamoto : Antitumor efficacy of sequential treatment with docetaxel and 5-fluorouracil against human oral cancer cells, International Journal of Oncology, Vol.41, No.3, 1148-1156, 2012. (Summary) Docetaxel (DOC) and 5-fluorouracil (5-FU) are important anticancer agents widely used in the treatment of a variety of cancers including oral squamous cell carcinoma (OSCC). The purpose of this study was to determine the antitumor efficacy of the sequential administration of DOC and 5-FU against OSCC cells (B88 and CAL27 cells) in vitro and in vivo. In in vitro growth inhibition assays, sequential treatment with DOC followed by 5-FU was more effective in inhibiting cancer cell growth than 5-FU followed by DOC, single treatment with DOC or 5-FU, or combined treatment with DOC and 5-FU. Furthermore, DOC followed by 5-FU significantly inhibited tumor growth in vivo compared to 5-FU followed by DOC. To understand the mechanisms underlying the enhanced growth inhibitory effect of the administration sequence, DOC followed by 5-FU, we examined the expression of 5-FU metabolic enzymes such as thymidylate synthase (TS), dihydropyrimidine dehydrogenase (DPD) and orotate phosphoribosyl transferase (OPRT), which were known to regulate the antitumor effect of 5-FU, by real-time RT-PCR and western blot analysis. Downregulation of TS and DPD expression and upregulation of OPRT expression were induced by DOC treatment, suggesting that DOC enhanced the efficacy of 5-FU by altering the expression of its metabolic enzymes. These results indicate that sequential treatment with DOC followed by 5-FU could be a promising therapeutic strategy for oral cancer. (Keyword) Animals / Antineoplastic Combined Chemotherapy Protocols / Cell Line, Tumor / Dihydrouracil Dehydrogenase (NADP) / Down-Regulation / Fluorouracil / Humans / Mice / Mice, Nude / Mouth Neoplasms / Orotate Phosphoribosyltransferase / Taxoids / Thymidylate Synthase / Up-Regulation / Xenograft Model Antitumor Assays (Tokushima University Institutional Repository) ● Metadata: 113602 (Link to Publication Site) ● Publication site (DOI): 10.3892/ijo.2012.1544 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 22766915 ● Search Scopus @ Elsevier (PMID): 22766915 ● Search Scopus @ Elsevier (DOI): 10.3892/ijo.2012.1544 (Tokushima University Institutional Repository: 113602, DOI: 10.3892/ijo.2012.1544, PubMed: 22766915)
72.	Satoshi Hino, Hiroyuki Hamakawa, Youji Miyamoto, Kazuo Ryoke, Jyouji Sekine, Akira Sasaki, Tetsuya Yamamoto and The Oral Cancer Study Group Of Chugoku-shikoku : Effects of a concurrent chemoradiotherapy with S-1 for locally advanced oral cancer, Oncology Letters, Vol.2, No.5, 839-843, 2011. (Summary) A number of regimens composed of concurrent chemoradiotherapy (CCRT) have been attempted as radical or adjuvant therapies for locally advanced oral cancer. CCRT with S-1 is considered promising due to its efficacy and simplicity of application. Patients (n=16) with locally advanced squamous cell carcinoma of the oral cavity were enrolled. Chemotherapy consisted of oral administration of S-1 (65 mg/m(2)) for 14 consecutive days followed by a 1-week rest. Radiation treatment at a dose of 30 Gy in 15 fractions was administered concomitantly with S-1. A course schedule of 3 weeks of treatment was applied twice. The overall response rate was 87.5%. Median progression-free survival and median overall survival were 6.3 and 42.5 months, respectively. Although no grade 4 adverse events were observed, grade 3 adverse events, such as anemia (12.5%), stomatitis (25%) and anorexia (18.8%) were present. Thus, CCRT with S-1 is an effective modality that can be safely conducted with minimal burden on patients. (Link to Publication Site) ● Publication site (DOI): 10.3892/ol.2011.347 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 22866137 ● Search Scopus @ Elsevier (PMID): 22866137 ● Search Scopus @ Elsevier (DOI): 10.3892/ol.2011.347 (DOI: 10.3892/ol.2011.347, PubMed: 22866137)
73.	Hirokazu Nagai, Natsumi Takamaru, Go Ohe, Daisuke Uchida, Tetsuya Tamatani, Kenji Fujisawa, Seiji Iwamoto and Youji Miyamoto : [Evaluation of Combination Chemotherapy with Oral S-1 Administration Followed by Docetaxel by Superselective Intra-Arterial Infusion for Patients with Oral Squamous Cell Carcinomas.], Japanese Journal of Cancer and Chemotherapy, Vol.38, No.5, 777-781, 2011. (Summary) The purpose of this study was to evaluate the effectiveness and adverse events of combination chemotherapy with oral S-1 administration following docetaxel(DOC)treatment by superselective intra-arterial infusion as neo-adjuvant chemotherapy (NAC)for patients with oral squamous cell carcinoma. Thirteen patients were enrolled in this study(9 men and 4 women, with a mean age of 61. 0 years). All patients were given S-1 65mg/m / 2 per day for 14 days, and DOC 40-50mg/m2 by intraarterial infusion was administered. The locoregional response evaluated 3 weeks after administration was 100%, including a 69. 2% complete response. According to Oboshi and Shimosato's classification, histological evaluation of surgical specimens revealed that 3 cases were Grade IIa, 4 cases Grade IIb, 1 case Grade IVa, and 4 cases Grade IVc. The severe side effects were neutropenia and cerebral infarction. The present study suggests that combination chemotherapy with S-1 and DOC by superselective intra-arterial infusion would be an effective and safe regimen in NAC for oral squamous cell carcinomas. (Keyword) Administration, Oral / Adult / Aged / Aged, 80 and over / Antineoplastic Combined Chemotherapy Protocols / Carcinoma, Squamous Cell / Cerebral Infarction / Drug Combinations / Female / Humans / Infusions, Intra-Arterial / Male / Middle Aged / Mouth Neoplasms / Neoplasm Staging / Neutropenia / Oxonic Acid / Taxoids / Tegafur (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 21566436 ● Summary page in Scopus @ Elsevier: 2-s2.0-79960998915 (PubMed: 21566436, Elsevier: Scopus)
74.	Daisuke Uchida, Tomitaro Onoue, Nobuyuki Kuribayashi, Yoshifumi Tomizuka, Tetsuya Tamatani, Hirokazu Nagai and Youji Miyamoto : Blockade of CXCR4 in oral squamous cell carcinoma inhibits lymph node metastases., European Journal of Cancer, Vol.47, No.3, 452-459, 2011. (Summary) We have previously demonstrated that a stromal cell-derived factor-1 (SDF-1; CXCL12)/CXCR4 system is involved in the establishment of lymph node metastasis in oral squamous cell carcinoma (OSCC). In this study, we investigated whether the blockade of CXCR4 inhibits lymph node metastasis in B88 OSCC cells. These cells harbour a functional CXCR4 and have the potential to metastasise to the lymph node in vivo. Following introduction of a vector that expresses short hairpin small interfering RNA (shRNA) against CXCR4, we isolated three clones (shCXCR4-16, -17 and -21) that showed decreased expression of CXCR4 mRNA. These clones also had reduced CXCR4 protein levels and showed impairments in calcium flux and cell migration in response to SDF-1. These cells were orthotopically inoculated into the masseter muscle of nude mice. Lymph node metastases, loss in body weight and tumour volumes were significantly inhibited in mice inoculated with shCXCR4-17 cells compared to mice inoculated with control cells. SDF-1-induced migration of B88 cells was significantly inhibited in vitro by the treatment with 1,1'-[1,4-phenylenebis(methylene)]bis-1,4,8,11-tetraazacyclotetradecane octahydrochloride (AMD3100), a CXCR4 antagonist. Subcutaneous administration of AMD3100 significantly inhibited the lymph node metastases of B88 cells when they were orthotopically inoculated into the masseter muscle of nude mice. Moreover, the enhanced production of interleukin (IL)-6 and IL-8 in response to SDF-1 was inhibited by shRNA against CXCR4 or by treatment with AMD3100. These results suggest that blockade of CXCR4 may be a potent anti-metastatic therapy against lymph node metastases in cases of CXCR4-related OSCC. (Link to Publication Site) ● Publication site (DOI): 10.1016/j.ejca.2010.09.028 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 20965717 ● Search Scopus @ Elsevier (PMID): 20965717 ● Search Scopus @ Elsevier (DOI): 10.1016/j.ejca.2010.09.028 (DOI: 10.1016/j.ejca.2010.09.028, PubMed: 20965717)
75.	Seiko Tatehara, Youji Miyamoto, Masaaki Takechi, Yukihiro Momota and Tetsuya Yuasa : Osteoporosis influences the early period of the healing after distraction osteogenesis in a rat osteoporotic model., Journal of Cranio-Maxillo-Facial Surgery, Vol.39, No.1, 2-9, 2010. (Summary) Despite the clinical adoption of distraction osteogenesis (DO), studies examining the bone healing process at the distraction gap in osteoporotic bone are limited. We examined the effect of osteoporosis in the ovariectomized rat on DO. (Link to Publication Site) ● Publication site (DOI): 10.1016/j.jcms.2010.03.001 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 20456966 ● Search Scopus @ Elsevier (PMID): 20456966 ● Search Scopus @ Elsevier (DOI): 10.1016/j.jcms.2010.03.001 (DOI: 10.1016/j.jcms.2010.03.001, PubMed: 20456966)
76.	Seiko Tatehara, Kenji Fujisawa, Hirokazu Nagai, Shuji Shigemoto, Kazuo Okura, Naozumi Ishimaru, Yoshio Hayashi and Youji Miyamoto : 切除からインプラントを維持源としたエピテーゼまで一貫治療を行った上顎洞悪性線維性組織球腫の1例, Shikoku Dental Research, Vol.22, No.2, 179-183, 2010. (Tokushima University Institutional Repository) ● Metadata: 109796 (Tokushima University Institutional Repository: 109796)
77.	Daisuke Uchida, Tomitaro Onoue, Nasima-Mila Begum, Nobuyuki Kuribayashi, Yoshifumi Tomizuka, Tetsuya Tamatani, Hirokazu Nagai and Youji Miyamoto : Vesnarinone downregulates CXCR4 expression via upregulation of Krüppel-like factor 2 in oral cancer cells., Molecular Cancer, Vol.8, 62, 2009. (Summary) BACKGROUND: We have demonstrated that the stromal cell-derived factor-1 (SDF-1; CXCL12)/CXCR4 system is involved in the establishment of lymph node metastasis in oral squamous cell carcinoma (SCC). Chemotherapy is a powerful tool for the treatment of oral cancer, including oral SCC; however, the effects of chemotherapeutic agents on the expression of CXCR4 are unknown. In this study, we examined the expression of CXCR4 associated with the chemotherapeutic agents in oral cancer cells. RESULTS: The expression of CXCR4 was examined using 3 different chemotherapeutic agents; 5-fluorouracil, cisplatin, and vesnarinone (3,4-dihydro-6-[4-(3,4-dimethoxybenzoyl)-1-piperazinyl]-2-(1H)-quinolinone) in B88, a line of oral cancer cells that exhibits high levels of CXCR4 and lymph node metastatic potential. Of the 3 chemotherapeutic agents that we examined, only vesnarinone downregulated the expression of CXCR4 at the mRNA as well as the protein level. Vesnarinone significantly inhibited lymph node metastasis in tumor-bearing nude mice. Moreover, vesnarinone markedly inhibited 2.7-kb human CXCR4 promoter activity, and we identified the transcription factor, Krüppel-like factor 2 (KLF2), as a novel vesnarinone-responsive molecule, which was bound to the CXCR4 promoter at positions -300 to -167 relative to the transcription start site. The forced-expression of KLF2 led to the downregulation of CXCR4 mRNA and impaired CXCR4 promoter activity. The use of siRNA against KLF2 led to an upregulation of CXCR4 mRNA. CONCLUSION: These Results indicate that vesnarinone downregulates CXCR4 via the upregulation of KLF2 in oral cancer. (Keyword) Animals / Antineoplastic Agents / Cell Line, Tumor / Cell Movement / Cisplatin / Down-Regulation / Flow Cytometry / Fluorouracil / Gene Expression Regulation, Neoplastic / Hela Cells / Humans / Kruppel-Like Transcription Factors / Luciferases / Mice / Mice, Inbred BALB C / Mice, Nude / Mouth Neoplasms / Oligonucleotide Array Sequence Analysis / Promoter Regions, Genetic / Quinolines / RNA Interference / Receptors, CXCR4 / Reverse Transcriptase Polymerase Chain Reaction / Tumor Burden / Xenograft Model Antitumor Assays (Link to Publication Site) ● Publication site (DOI): 10.1186/1476-4598-8-62 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 19671192 ● Search Scopus @ Elsevier (PMID): 19671192 ● Search Scopus @ Elsevier (DOI): 10.1186/1476-4598-8-62 (DOI: 10.1186/1476-4598-8-62, PubMed: 19671192)
78.	Yukihiro Momota, Kazuhito Satomura, Tetsuya Yuasa, Keiko Kudoh, Hideyuki Takano, Yoshio Hayashi and Youji Miyamoto : 著しい骨吸収を伴う歯性上顎洞炎の1例, Shikoku Dental Research, Vol.21, No.2, 407-411, 2009. (Keyword) 宮本
79.	Kenji Fujisawa, Seiko Tatehara, Tetsuya Yuasa, Yukihiro Momota, Eiji Yamauchi and Youji Miyamoto : 即時荷重インプラントに関する臨床的検討:3年経過時の臨床成績 ., Journal of Japanese Society of Oral Implantology, Vol.21, No.4, 563-569, 2008. (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1390001205508947712 (CiNii: 1390001205508947712)
80.	Kenji Fujisawa, Eiji Yamauchi, Seiko Takehara, Hideyuki Takano, Tetsuya Yuasa, Yukihiro Momota and Youji Miyamoto : 共鳴振動周波数分析装置を用いた即時荷重インプラント安定性の経時的評価, 日本顎顔面インプラント学会誌, Vol.7, No.3, 205-210, 2008.
81.	Masaaki Takechi, Youji Miyamoto, Kunio Ishikawa, Yukihiro Momota, Tetsuya Yuasa, Seiko Tatehara, Hideyuki Takano, Shiho Minamiguchi and Masaru Nagayama : Histological evaluation of apatite cement containing atelocollagen, Dental Materials Journal, Vol.26, No.2, 194-200, 2007. (Summary) Tissue response to apatite cement (AC) containing atelocollagen (AC (ate)) was evaluated using conventional AC (c-AC) as a control material. At one week, the only difference between AC (ate) and c-AC was found in the soft tissue response. With c-AC, a moderate inflammatory response was exhibited: small particles of c-AC were scattered in the cutaneous tissue and many foreign body giant cells were aggregated around the scattered c-AC, whereas AC (ate) showed only a slight inflammatory response with few foreign body giant cells. In terms of bone tissue response, difference between AC (ate) and c-AC was observed at four weeks. New bone formation was observed along the cement at the edge of the pre-existing cortical bone in both c-AC and AC (ate). However, in the case of AC (ate), more abundant and thicker new bone was formed along the cement in the bone marrow when compared with c-AC. (Keyword) Animals / Bone Cements / Bone Regeneration / Bone and Bones / Cattle / Collagen / Foreign-Body Reaction / Hydroxyapatites / Male / Rats / Rats, Wistar / Subcutaneous Tissue / X-Ray Diffraction (Link to Publication Site) ● Publication site (DOI): 10.4012/dmj.26.194 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 17621934 ● Search Scopus @ Elsevier (PMID): 17621934 ● Search Scopus @ Elsevier (DOI): 10.4012/dmj.26.194 (DOI: 10.4012/dmj.26.194, PubMed: 17621934)
82.	舘原誠晃, 武知正晃, Yukihiro Momota, 湯浅哲也, Hideyuki Takano, 徳山麗子, Youji Miyamoto and 長山勝 : HAP-PLGA複合体による顎骨再生への応用に関する実験的研究, Japanese Journal of Oral & Maxillofacial Surgery, Vol.53, No.10, 588-593, 2007. (Keyword) *Hydroxyapatite
83.	成田王彦, Masayuki Kon, Hirokazu Nagai, Masayuki Fukuta, Seiji Tanaka, 福士省治, 五十嵐淳子 and Youji Miyamoto : 硫酸カリウム水溶液による急速加熱型クリストバライト埋没材の鋳型放置時間の短縮, Journal of Nippon Academy of Dental Technology, Vol.27, No.2, 115-120, 2006. (Keyword) potassium sulfate / setting time / setting expansion / thermal expansion / size accuracy (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1570854175412706048 (CiNii: 1570854175412706048)
84.	Hirokazu Nagai, 中田憲, 畠山成知, 福田雅幸, 南條博 and Youji Miyamoto : 頬部に生じた孤立性神経線維腫の1例, Japanese Journal of Oral & Maxillofacial Surgery, Vol.52, No.11, 592-595, 2006. (Summary) Neurofibroma is a benign tumor originating from Schwann cells, perineural fibroblasts, or both. It is commonly associated with neurofibromatosis (von Recklinghausen's disease), while solitary neurofibroma rarely occurs in the oral region. We report a rare case of solitary neurofibroma arising in the cheek. The patient was a 47-year-old woman who had no symptoms, except for a painless swelling in the right side of the cheek. We found neither cafe-au-lait spots nor tumors on the skin of her body. Intraoral examination revealed a solitary, mobile, welldelimited, elastic soft mass 25 mm in diameter in the cheek. CT scan revealed an enhanced tumor mass in the cheek. The tumor was surgically removed. Histopathologically, it was composed of proliferating spindle cells and collagen-like fibers. Immunohistochemical studies showed positive staining of tumor cells with S-100 protein. The histopathological diagnosis was neurofibroma. About 12 months after the operation, there is no evidence of recurrence. (Keyword) neurofibroma / solitary / cheek (Link to Publication Site) ● Publication site (DOI): 10.5794/jjoms.52.592 (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1390282681510124416 ● Search Scopus @ Elsevier (DOI): 10.5794/jjoms.52.592 (DOI: 10.5794/jjoms.52.592, CiNii: 1390282681510124416)
85.	Takayoshi Ohnuki, Masayuki Fukuda, Akira Nakata, Hirokazu Nagai, Tetsuyuki Takahashi, Takashi Sasano and Youji Miyamoto : Evaluation of the position, mobility, and morphology of the disc by MRI before and after four different treatments for temporomandibular joint disorders., Dento Maxillo Facial Radiology, Vol.35, No.2, 103-109, 2006. (Summary) The purpose of this study was to evaluate changes in disc position, mobility, and morphology in patients with temporomandibular joint disorders (TMD) in response to four different treatments, splint therapy, pumping manipulation, arthrocentesis, and arthroscopic surgery, using magnetic resonance imaging (MRI). Eighty-five joints (85 patients) with unilateral internal derangement or osteoarthritis that were successfully treated were included in this study. The patients were divided into four groups as follows: splint therapy group, pumping manipulation group, arthrocentesis group, and arthroscopic surgery group. Changes in the disc position, mobility, and morphology before and after treatment were compared among the four groups using MRI. All discs showed anterior disc displacement (ADD) without reduction before treatment. Only 10% of the joints became ADD with reduction after treatment, and the other joints remained ADD without reduction in spite of treatment. Discs treated by arthroscopic surgery were located more anteriorly compared with pre-treatment. In pre-treatment MRI, the rate of stuck disc increased as the stage of the treatment advanced. In post-treatment MRI, all temporomandibular joints (TMJs) had mobile discs. The disc deformity advanced after arthrocentesis and arthroscopic surgery. Even though clinical signs and symptoms were alleviated by treatment, most discs remained ADD without reduction on MRI in spite of treatment. This suggests that the four treatments do not necessarily improve the position and deformity of the disc, and that arthroscopic surgery advances the deformity and anterior displacement of the disc. Disc mobility is important for improving clinical signs and symptoms. (Keyword) Adolescent / Adult / Aged / Arthroscopy / Dislocations / Female / Follow-Up Studies / Humans / magnetic resonance imaging / Male / Manipulation, Orthopedic / Middle Aged / Occlusal Splints / Osteoarthritis / Paracentesis / Range of Motion, Articular / Temporomandibular Joint Disc / Temporomandibular Joint Disorders (Link to Publication Site) ● Publication site (DOI): 10.1259/dmfr/25020275 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 16549437 ● Summary page in Scopus @ Elsevier: 2-s2.0-33645324023 (DOI: 10.1259/dmfr/25020275, PubMed: 16549437, Elsevier: Scopus)
86.	Takahiro Otani, Noriaki Tomura, Koumei Narita, Satoshi Takahashi, Ikuo Sakuma, Kaku Yasuda, Jiro Watarai, Takayoshi Ohnuki and Youji Miyamoto : Serial contrast-enhanced MRI of the dondyle and posterior disk attachment for assessing temporomandibular joint disorders, Akita Journal of Medicine, Vol.32, No.3-4, 175-186, 2006.
87.	Hirokazu Nagai, Youji Miyamoto, Akira Nakata, Shigetomo Hatakeyama, Yoichi Iwanami and Masayuki Fukuda : Isolation and characterization of synovial cells from the human temporomandibular joint., Journal of Oral Pathology & Medicine, Vol.35, No.2, 104-110, 2006. (Summary) The synovial tissues with temporomandibular disorders (TMDs) often show chronic inflammatory changes and the synovial cells participate in the pathogenic processes of TMDs. The synovial membrane is composed of a synovial lining layer and a connective sublining layer. The synovial lining layer is made up of two kinds of cells: macrophage-like type A and fibroblastic type B cells. The aim of this study was to isolate and characterize synovial cells from the human temporomandibular joint (TMJ). (Keyword) Antigens, CD / Antigens, Differentiation, Myelomonocytic / Biological Markers / cell separation / Cells, Cultured / Connective Tissue Cells / Fibroblasts / Heat-Shock Proteins / Humans / immunohistochemistry / Laminin / Macrophages / Phenotype / Procollagen-Proline Dioxygenase / Synovial Membrane / temporomandibular joint / Vimentin (Link to Publication Site) ● Publication site (DOI): 10.1111/j.1600-0714.2006.00369.x (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 16430741 ● Search Scopus @ Elsevier (PMID): 16430741 ● Search Scopus @ Elsevier (DOI): 10.1111/j.1600-0714.2006.00369.x (DOI: 10.1111/j.1600-0714.2006.00369.x, PubMed: 16430741)
88.	成田王彦, 今政幸, 田中清志, Hirokazu Nagai, 福田雅幸, 福士省冶, 五十嵐淳子 and Youji Miyamoto : 硫酸カリウム水溶液による急速加熱型クリストバライト埋没材の鋳型放置時間の短縮クラウン適合精度，硬化膨張，加熱膨張に及ぼす影響, Journal of Nippon Academy of Dental Technology, Vol.27, No.2, 115-120, 2006.
89.	Koutaro Miyoshi, 大貫敬嘉, Hirokazu Nagai, 武蔵哲貞, 柏木了, Masayuki Fukuta and Youji Miyamoto : 下顎枝矢状分割術を施行した外科的矯正治療前後における顎関節MRI所見の変化, Journal of the Japanese Society for the Temporomandibular Joint, Vol.17, No.3, 224-231, 2005. (Keyword) MRI findings / surgical orthodontic treatment / SSRO / temporomandibular joint (Link to Publication Site) ● Publication site (DOI): 10.11246/gakukansetsu1989.17.224 (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1390001204420886912 ● Search Scopus @ Elsevier (DOI): 10.11246/gakukansetsu1989.17.224 (DOI: 10.11246/gakukansetsu1989.17.224, CiNii: 1390001204420886912)
90.	Kaoru Yamaoka, Masayuki Fukuda, Shigetomo Hatakeyama, Daigo Murayama, Ryo Kashiwagi, Tetsusada Musashi, Takayoshi Ohnuki, Kotaro Miyoshi, Hirokazu Nagai, Hiroshi Nanjo and Youji Miyamoto : [Evaluation of a combination chemotherapy with docetaxel and nedaplatin for patients with oral squamous cell carcinomas]., Japanese Journal of Cancer and Chemotherapy, Vol.32, No.10, 1411-1414, 2005. (Summary) The purpose of this study was to evaluate the effectiveness and safety of combination chemotherapy with docetaxel (TXT) and nedaplatin (CDGP) for patients with oral squamous cell carcinomas. Eight patients were enrolled in this study (4 men and 4 women, with a mean age of 61.7 years). TXT and CDGP were administered at a dose of 60 mg/m(2) and 70 mg/m(2) by drip infusion for 120 minutes, respectively. Three patients received one more administration 4 weeks after the first one. The locoregional response was evaluated 4 weeks after the final administration of TXT and CDGP. As a result, the locoregional response rate after 1 course was 62.5% including 25.0% of complete response (CR). The response rate after 2 courses was 100.0% with 66.7% of CR. According to Oboshi and Shimosato's classification, histological evaluation of surgical specimens revealed that four cases were Grade IIa, two cases Grade IIb, and two cases Grade IV. The severe adverse events were neutropenia and leukopenia, which were effectively managed with granulocyte colony-stimulating factor (G-CSF). No other severe side effects were recognized. The present study suggested that the combination chemotherapy with TXT and CDGP would be an effective and safe regimen in neo-adjuvant chemotherapy for oral squamous cell carcinomas. (Keyword) Adult / Aged / Alopecia / Antineoplastic Combined Chemotherapy Protocols / Carcinoma, Squamous Cell / Chemotherapy, Adjuvant / Drug Administration Schedule / Female / Granulocyte Colony-Stimulating Factor / Humans / Leukopenia / Male / Middle Aged / Mouth Neoplasms / Neoplasm Staging / Neutropenia / Organoplatinum Compounds / Taxoids (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 16227739 ● Summary page in Scopus @ Elsevier: 2-s2.0-27744485118 (PubMed: 16227739, Elsevier: Scopus)
91.	Kenji Fujisawa, Youji Miyamoto, Yukihiro Momota, 日比弓紀子 and Masaru Nagayama : Comparison of Resonance Frequency Analyzer and Tooth Mobility Measurement Device for the Evaluation of Dental Implant Stability, Journal of Japanese Society of Oral Implantology, Vol.18, No.3, 406-414, 2005. (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1390001205506100608 (CiNii: 1390001205506100608)
92.	山岡薫, 福田雅幸, 大貫敬嘉, 三好康太郎, 永井宏和, 面川進 and Youji Miyamoto : Usefulness of the autologous transfusion in the orthognathic surgery, Journal of Japanese Society of Autologous Blood Transfusion, Vol.18, No.1, 79-83, 2005. (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1573105975220424192 (CiNii: 1573105975220424192)
93.	田中清志, 福田雅幸, 神谷修, 成田王彦 and Youji Miyamoto : 顎義歯支持におけるインプラント体の配置に関する研究:ストレート型埋入モデルとアーチ型埋入モデルとの比較, 日本歯技, No.435, 33-40, 2005.
94.	村山大悟, Hirokazu Nagai, 戸嶋慎一, 福田雅幸, 小野寺健 and Youji Miyamoto : 高齢者の下顎に発生した顎骨中心性神経鞘腫の1例, Journal of The Japanese Stomatological Society, Vol.54, No.3, 368-372, 2005. (Keyword) Schwannoma / Mandible / 下顎骨 / Elderly patient (Link to Publication Site) ● Publication site (DOI): 10.11277/stomatology1952.54.368 (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1390282681412308224 ● Search Scopus @ Elsevier (DOI): 10.11277/stomatology1952.54.368 (DOI: 10.11277/stomatology1952.54.368, CiNii: 1390282681412308224)
95.	福田雅幸, Youji Miyamoto, 武蔵哲貞, 大貫敬嘉 and Hirokazu Nagai : チタンメッシュトレーと腸骨骨髄海綿骨細片移植による下顎骨再建後のインプラント義歯の機能評価, Journal of Japanese Society of Oral Implantology, Vol.18, No.2, 302-309, 2005. (Keyword) dental implant / mandibular reconstruction / particulate cancellous bone and marrow graft / segmental defect / titanium mesh tray (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1390001205506693888 (CiNii: 1390001205506693888)
96.	Youji Miyamoto, Kenji Fujisawa, 福田雅幸, Tetsuya Yuasa, Masaru Nagayama, Eiji Yamauchi, Fumiaki Kawano and Daisuke Hinode : 即時荷重インプラントに関する臨床的検討: 臨床術式と1年経過時の臨床成績, Journal of Japanese Society of Oral Implantology, Vol.18, No.2, 292-301, 2005. (Keyword) dental implant / early loading / immediate loading / load (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1571135650275179904 (CiNii: 1571135650275179904)
97.	成田王彦, Youji Miyamoto, Masayuki Kon, 田中清志 and 神谷修 : 硫酸カリウム水溶液による急速加熱型クリストバライト埋没材の鋳型放置時間短縮の試み, Journal of Nippon Academy of Dental Technology, Vol.26, No.1, 16-20, 2005. (Keyword) setting time / hardening accelerator / size accuracy / investment / potassium sulfate (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1571417125213049344 (CiNii: 1571417125213049344)
98.	田中清志, Youji Miyamoto, 成田王彦, 飯野光喜 and 福田雅幸 : 新しい外鼻矯正装置付口蓋床の作製法と臨床応用, 日本歯科技工学会雑誌, Vol.26, No.1, 89-93, 2005.
99.	Tetsuya Yuasa, Youji Miyamoto, Masayuki Kon, Kunio Ishikawa, Masaaki Takechi, Yukihiro Momota, Seiko Tatehara, Hideyuki Takano, Shiro Minamiguchi and Masaru Nagayama : Proliferation and Differentiation of Cultured MC3T3-E1 Osteoblasts on Surface-layer Modified Hydroxyapatite Ceramic with Acid and Heat Treatments, Dental Materials Journal, Vol.24, No.2, 207-212, 2005. (Summary) Effects of functionally gradient calcium phosphate consisting of hydroxyapatite (HAP) and alpha-tricalcium phosphate (alpha-TCP) on proliferation and differentiation of osteoblasts were evaluated using MC3T3-E1 cells. There were no significant differences in the proliferation of MC3T3-E1 cells among HAP-alpha-TCP functionally gradient calcium phosphate, pure HAP, and cell culture plastic wells. mRNA expressions of type I collagen, alkaline phosphate, and osteocalcine were evaluated as indexes of initial; mid-stage, and late-stage osteoblastic differentiation. Basically, HAP-alpha-TCP functionally gradient calcium phosphate and pure HAP enhanced the expressions of the three markers when compared with that of cell culture plastic wells. For type I collagen and alkaline phosphate expressions, HAP-alpha-TCP functionally gradient calcium phosphate showed the same expression level as pure HAP. For osteocalcine expression, HAP-alpha-TCP functionally gradient calcium phosphate showed a higher level than pure HAP. We concluded, therefore, HAP-alpha-TCP functionally gradient calcium phosphate has good potential to be a bone filler material with high osteoconductivity. (Keyword) Osteoblasts / α-tricalcium phosphate / hydroxyapatite (Link to Publication Site) ● Publication site (DOI): 10.4012/dmj.24.207 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 16022440 ● Search Scopus @ Elsevier (PMID): 16022440 ● Search Scopus @ Elsevier (DOI): 10.4012/dmj.24.207 (DOI: 10.4012/dmj.24.207, PubMed: 16022440)
100.	Masayuki Kon, Mayumi Luciana Hirakata, Youji Miyamoto, H Kasahara and Kenzo Asaoka : Strengthening of calcium phosphate cement by compounding calcium carbonate whiskers, Dental Materials Journal, Vol.24, No.1, 104-110, 2005. (Summary) The purpose of this study was to investigate how aragonite (calcium carbonate) whiskers influenced the strengthening and carbonating of alpha-tricalcium phosphate (alpha-TCP) based calcium phosphate cement. Aragonite whiskers of 0.95 microm width with an aspect ratio of 6.6 were prepared. The cement powder, alpha-TCP containing 0-50 mass% aragonite whisker, was mixed with 0.6 mol/L NaH2PO4 solution and incubated at 37 degrees C and 100% relative humidity. Diametral tensile strength (DTS) value increased significantly when appropriate amount of aragonaite whiskers was added. For example, DTS value of set cement containing 20 mass% aragonite whisker was 5.8 +/- 0.5 MPa, whereas DTS value of set cement containing no whiskers was 1.3 +/- 0.2 MPa after 1-week incubation. SEM observation revealed that the shape of the whiskers and the densification of the structure could have contributed to the strengthening of the set cement. Moreover, FTIR spectra implied that a bone-like carbonated apatite was precipitated in the cement. The results obtained in the present study revealed that the shape as well as any slight dissolution of aragonite whiskers could contribute to improving the properties of a-TCP based calcium phosphate cement. (Keyword) Apatites / Calcium Carbonate / Calcium Phosphates / Carbon / Crystallography, X-Ray / Dental Cements / Dental Stress Analysis / Materials Testing / Microscopy, Electron, Scanning / Spectroscopy, Fourier Transform Infrared / Tensile Strength (Link to Publication Site) ● Publication site (DOI): 10.4012/dmj.24.104 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 15881216 ● Summary page in Scopus @ Elsevier: 2-s2.0-20644468599 (DOI: 10.4012/dmj.24.104, PubMed: 15881216, Elsevier: Scopus)
101.	山岡薫, 福田雅幸, 大貫敬嘉, 三好康太郎, Hirokazu Nagai, 面川進 and Youji Miyamoto : 上顎骨切り術(Le Fort I型骨切り術)における貯血式自己血輸血の有用性に関する検討, Journal of Japanese Society of Autologous Blood Transfusion, Vol.18, No.1, 79-83, 2005.
102.	福田雅幸, Youji Miyamoto, 飯野光喜 and 幸地省子 : 常温重合型粘弾性レジンを用いた小型鼻口腔瘻栓塞子, Journal fo Japanese Cleft Palate Association, Vol.29, No.3, 322-324, 2004. (Keyword) oronasal fistula / obturator / self-curing viscoelastic resin (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1390282680429996544 (CiNii: 1390282680429996544)
103.	Youji Miyamoto, Kenji Fujisawa, Takashi Sumitomo, Tetsuya Yuasa, Masaru Nagayama, Eiji Yamauchi, Fumiaki Kawano and Daisuke Hinode : Effect of Surface Topography on Ssseointegration Establishment of Dental Implant, --- Comparison between Smooth and Rough Surfaces ---, Journal of Japanese Society of Oral Implantology, Vol.17, No.2, 216-226, 2004. (Keyword) dental implant / early failure / osseointegration / prognosis / surface roughness (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1390282680487133824 (CiNii: 1390282680487133824)
104.	Tetsuya Yuasa, Youji Miyamoto, Hiroaki Nakanishi, Kenji Fujisawa, Seiko Tatehara, Masayuki Taki and Masaru Nagayama : Esthetic and Functional Repairment of Malunion afterMultiple Maxillofacial Bone Fracture Using Orthognathic Surgery and Bone Graft;Report of a Case, Japanese Society of Oral and Maxillofacial Traumatology, Vol.3, No.1, 26-31, 2004. (Keyword) Orthognathic surgery / Malunion after multiple maxillofacial bone fracture / Occlusal plane table
105.	山之内浩司, Nobuyuki Kamata, Youji Miyamoto, Yukihiro Momota and Eiichiro Kitaoka : 舌体部へのピアス迷入の1例, Japanese Journal of Oral & Maxillofacial Surgery, Vol.50, No.4, 255-258, 2004. (Summary) Body piercing is becoming more popular. Increasing popularity of tongue piercing has led to a rise in infectious complications and secondary metal allergy. We report a rare case of a deeply impacted metal barbelltype pierced ornament into the tongue.<BR>A 19-year-old man was referred to our hospital by a general practitioner bacause of discomfort of the tongue and difficulty in eating. The patient had a slight swelling of the tongue. Physical examination revealed a hard mass in the body of the tongue. Mandibular occlusal radiographs showed a radiopaque body measuring about 3×3mm in the center of the tongue. The clinical diagnosis was a foreign body in the tongue. The foreign body was removed surgically under local anesthesia. We performed element analysis of the removed foreign body. The patient's progress has been good, without functional disorders of the tongue. (Keyword) tongue pierce / foreign body / element analysis (Link to Publication Site) ● Publication site (DOI): 10.5794/jjoms.50.255 (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1390001206530515712 ● Search Scopus @ Elsevier (DOI): 10.5794/jjoms.50.255 (DOI: 10.5794/jjoms.50.255, CiNii: 1390001206530515712)
106.	Masaaki Takechi, Youji Miyamoto, Yukihiro Momota, Tetsuya Yuasa, Seiko Tatehara, Masaru Nagayama and Kunio Ishikawa : Effects of various sterilization methods on the setting and mechanical properties of apatite cement, Journal of Biomedical Materials Research. Part B, Applied Biomaterials, Vol.69B, No.1, 58-63, 2004. (Summary) Sterilization capability is a necessary requirement for any material that is to be used in a medical application. Therefore, it is necessary for apatite cement (AC) to be sterilized. Because there is little information on the sterilization methods of AC, the aims of this investigation were to evaluate the effects of various sterilization methods, including steam, dry heat, ethylene oxide (EtO) gas, and gamma irradiation sterilizations, on the setting and mechanical properties of AC. In the case of steam sterilization, because AC powder aggregated before setting-time measurements, the setting time could not be measured. When the powder was sterilized by dry heat or EtO gas, the setting time was prolonged significantly and the wet diametral tensile strength (DTS) value decreased significantly. Therefore, sterilizations with steam, dry heat, or EtO gas were suggested to be inappropriate methods for AC. Accordingly, the following experiments focused on gamma sterilization. The setting time of AC was retarded with an increase in gamma irradiation dose. The wet DTS value decreased with the increase in gamma irradiation dose. There was no compositional change due to the gamma irradiation. The following tests were carried out in order to examine the effect of the gamma irradiation on the setting reaction of AC in detail. Tetracalcium phosphate [TTCP: Ca(4)(PO(4))(2)O] and dicalcium phosphate anhydrous (DCPA: CaHPO(4)) were separately irradiated, and the cements were produced with the use of irradiated powder and nonirradiated powder. Although the wet DTS value of AC produced from irradiated TTCP and nonirradiated DCPA decreased with increasing gamma irradiation dose, there was no significant difference. In contrast, the wet DTS value of AC produced from irradiated DCPA and nonirradiated TTCP significantly decreased with the increase in gamma irradiation dose. In conclusion, although the detailed mechanism of the delayed setting time and decreased DTS value was not clarified by the present study, it was found that gamma irradiation affected DCPA more than TTCP. (Keyword) apatite / apatite cement / mechanical properties / gamma / sterilization (Link to Publication Site) ● Publication site (DOI): 10.1002/jbm.b.10031 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 15015210 ● Search Scopus @ Elsevier (PMID): 15015210 ● Search Scopus @ Elsevier (DOI): 10.1002/jbm.b.10031 (DOI: 10.1002/jbm.b.10031, PubMed: 15015210)
107.	Yukihiro Momota, Youji Miyamoto, Kunio Ishikawa, Masaaki Takechi, Tetsuya Yuasa, Seiko Tatehara and Masaru Nagayama : Effects of neutral sodium hydrogen phosphate on the setting property and hemostatic ability of hydroxyapatite putty as a local hemostatic agent for bone, Journal of Biomedical Materials Research. Part B, Applied Biomaterials, Vol.69B, No.1, 99-103, 2004. (Summary) Hydroxyapatite (HAP) putty has been reported to have good hemostatic ability and excellent biocompatibility. Although the setting reaction of HAP putty and resulting transformation to HAP is the reason for this excellent biocompatibility, it also limits the handling period. In this study, the relationship between the setting reaction of HAP putty and its hemostatic ability was investigated, where neutral sodium hydrogen phosphate concentration and post-preparation time were used as indexes. A higher concentration of neutral sodium hydrogen phosphate was found to result in decreased hemostatic ability. The hemostatic ability of HAP putty decreased with time after its preparation; thus it was important to use HAP putty within 10 min after its preparation. The adhesive strength of HAP putty to bone increased with time. Therefore reliable hemostasis can be expected with HAP putty. Although the limited handling time is a drawback, HAP putty is thought to have a good potential as a hemostatic agent-it is highly reliable, and has a high hemostatic ability with excellent biocompatibility. (Keyword) hemostatic agents / hydroxyapatite putty / apatite cement / calcium- phosphate cement / setting reaction (Link to Publication Site) ● Publication site (DOI): 10.1002/jbm.b.20034 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 15015217 ● Search Scopus @ Elsevier (PMID): 15015217 ● Search Scopus @ Elsevier (DOI): 10.1002/jbm.b.20034 (DOI: 10.1002/jbm.b.20034, PubMed: 15015217)
108.	Tetsuya Yuasa, Youji Miyamoto, Kunio Ishikiawa, Masaaki Takechi, Yukihiro Momota, Seiko Tatehara and Masaru Nagayama : Effects of apatite cements on proliferation and differentiation of human osteoblasts in vitro, Biomaterials, Vol.25, No.7-8, 1159-1166, 2004. (Summary) Although apatite cement (AC) and sintered hydroxyapatite (s-HAP) are known to show good osteoconductivity, it is not clear whether or not the degree of their osteoconductivity is the same. In addition, it has not been clarified whether or not it is dependent on the type of AC; conventional AC (c-AC), fast-setting AC (fs-AC) or anti-washout AC (aw-AC). The aim of this study was to investigate the effects of ACs on cultured human osteoblasts, as they may provide a useful index of osteoconductivity. Human osteoblasts were cultured on the surfaces of ACs and s-HAP, and were evaluated with respect to cell attachment, proliferation, and differentiation. We found that ACs and s-HAP showed similar cell attachment. No significant difference between ACs and s-HAP was found with respect to the proliferation of osteoblasts. In contrast, we found that the differentiation of osteoblasts was enhanced on the surface of ACs compared with that of s-HAP. However, there was no difference among the types of AC. We therefore concluded that AC may show better osteoconductivity than s-HAP, and that osteoconductivity of AC may be similar, regardless of the type of AC. (Keyword) Biocompatible Materials / Bone Cements / Cell Adhesion / cell differentiation / cell division / Cells, Cultured / Humans / Hydroxyapatites / Materials Testing / Molecular Conformation / Osseointegration / Osteoblasts (Link to Publication Site) ● Publication site (DOI): 10.1016/j.biomaterials.2003.08.003 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 14643589 ● CiNii @ National Institute of Informatics (CRID): 1572261551649164288 ● Search Scopus @ Elsevier (PMID): 14643589 ● Search Scopus @ Elsevier (DOI): 10.1016/j.biomaterials.2003.08.003 (DOI: 10.1016/j.biomaterials.2003.08.003, PubMed: 14643589, CiNii: 1572261551649164288)
109.	Ken'ichi Yokoyama, Kazuyuki Kaneko, Youji Miyamoto, Kenzo Asaoka, Jun'ichi Sakai and Michihiko Nagumo : Fracture associated with hydrogen absorption of sustained tensile-loaded titanium in acid and neutral fluoride solutions, Journal of Biomedical Materials Research. Part A, Vol.68, No.1, 150-158, 2004. (Summary) The fracture of commercial pure titanium in acid and neutral fluoride solutions has been examined by a sustained tensile-loading test and hydrogen thermal desorption analysis. It was found that the fracture of titanium occurred in neutral 2.0% NaF solution as well as in 2.0% acidulated phosphate fluoride (APF) solution. The time to fracture decreased with increasing applied stress in both 2.0% APF and 2.0% NaF solutions. In the case of the same applied stress, the time to fracture in the 2.0% APF solution was shorter than that in the 2.0% NaF solution. General corrosion was exhibited on the side surface of the tested specimens. The formation of sodium titanium fluoride was observed on the surface of the immersed specimens in the 2.0% APF solution. Hydrogen desorption of the tested specimen in the 2.0% APF solution was observed with a peak at approximately 600 degrees C. The amount of absorbed hydrogen was >300 mass ppm in the 2.0% APF solution under an applied stress for 24 h. The results of the present study imply that applying stress to titanium by immersing in fluoride solutions leads to the degradation of its mechanical properties. (Keyword) titanium / fracture / hydrogen embrittlement / corrosion / fluoride / STRESS-CORROSION CRACKING / TI SUPERELASTIC ALLOY / PURE TITANIUM / CATHODIC POLARIZATION / HYDROCHLORIC-ACID / HYDRIDE FORMATION / HOLLOW IMPLANTS / EMBRITTLEMENT / RESISTANCE / BEHAVIOR (Link to Publication Site) ● Publication site (DOI): 10.1002/jbm.a.20067 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 14661260 ● Search Scopus @ Elsevier (PMID): 14661260 ● Search Scopus @ Elsevier (DOI): 10.1002/jbm.a.20067 (DOI: 10.1002/jbm.a.20067, PubMed: 14661260)
110.	Kenji Fujisawa, Kazuhiro Yokoyama, Youji Miyamoto, Nobuyuki Kamata and Masaru Nagayama : 薬物療法を行った顎関節症患者の臨床的検討, Journal of the Japanese Society for the Temporomandibular Joint, Vol.15, No.3, 260-265, 2003. (Keyword) TMD patients / drug therapy / clinical study (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1390001204420398464 (CiNii: 1390001204420398464)
111.	Youji Miyamoto, Kenji Fujisawa, Masaaki Takechi, Yukihiro Momota, Tetsuya Yuasa, Seiko Tatehara, Masaru Nagayama and Eiji Yamauchi : Effect of the additional installation of implants in the posterior region on the prognosis of treatment in the edentulous mandibular jaw, Clinical Oral Implants Research, Vol.14, No.6, 727-733, 2003. (Summary) The aim of this study was to elucidate the effect of the additional installation of implants in the posterior region on the prognosis of treatment in the edentulous mandibular jaw. Fifteen patients who had received implants (Brånemark system, Nobel Biocare, Gotebörg, Sweden) in the edentulous mandible and completed a 1-year follow-up after the fitting of implant-anchored fixed prostheses were selected. In seven patients (Group A), four or five implants were installed between the mental foramina, and in eight patients (Group P), one or two implants, one on each side, were installed in the posterior regions in addition to the implants between the foramina. All implants of both groups achieved osseointegration. In Group A, there was no implant loss after loading. Six implants were lost in five patients of Group P within 1 year after loading. All of them were located in the posterior region. To elucidate whether or not the failure rate of the implants in the posterior region of Group P after loading was especially high, the failures were also compared with 89 implants, which were installed in the posterior region of the mandibles to support implant-anchored fixed partial prosthesis, during the same period (Group C). The cumulative survival rate of the implants of Group P was 60%, while that of the implants of Group C was 100% (P<0.001). When the survival rates of posterior implants with the same length of the two groups were compared, there were significant differences for the 7- and 10-mm-length implants only. These data demonstrate that the posterior implants in Group P are at greater risk. Deformation of the mandible due to jaw movement was thought to be the most likely cause of the implant loss. Therefore, when such modified treatment is chosen, it should be performed with meticulous attention. (Keyword) fully edentulous mandible / deformation / failure / distortion (Link to Publication Site) ● Publication site (DOI): 10.1046/j.0905-7161.2003.00958.x (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 15015949 ● Search Scopus @ Elsevier (PMID): 15015949 ● Search Scopus @ Elsevier (DOI): 10.1046/j.0905-7161.2003.00958.x (DOI: 10.1046/j.0905-7161.2003.00958.x, PubMed: 15015949)
112.	Kenji Fujisawa, Youji Miyamoto and Masaru Nagayama : Basic fibroblast growth factor and epidermal growth factor reverse impaired ulcer healing of the rabbit oral mucosa, Journal of Oral Pathology & Medicine, Vol.32, No.6, 358-366, 2003. (Keyword) bFGF / EGF / impaired ulcer healing / oral mucosa / wound healing / FACTOR-BETA / DESALIVATED RATS / TISSUE-REPAIR / WOUNDS / MODEL / EXPRESSION / SALIVA / MICE (Link to Publication Site) ● Publication site (DOI): 10.1034/j.1600-0714.2003.t01-1-00111.x (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 12787043 ● Search Scopus @ Elsevier (PMID): 12787043 ● Search Scopus @ Elsevier (DOI): 10.1034/j.1600-0714.2003.t01-1-00111.x (DOI: 10.1034/j.1600-0714.2003.t01-1-00111.x, PubMed: 12787043)
113.	Youji Miyamoto, Kenji Fujisawa, Tetsuya Yuasa, Yukihiro Momota, Masaru Nagayama, Eiji Yamauchi, Eiichi Bando and Daisuke Hinode : Evaluation of Risk Factors Concerning Loss of Osseointegration of Dental Implant, Journal of Japanese Society of Oral Implantology, Vol.16, No.2, 278-288, 2003. (Keyword) dental implant / late failure / osseointegration / clinical factor / risk factor (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1390001205509924608 (CiNii: 1390001205509924608)
114.	Youji Miyamoto, Seiko Tatehara, Kenji Fujisawa, Eiichiro Kitaoka, Tetsuya Yuasa, Nobuyuki Kamata, Masaru Nagayama and Eiji Yamauchi : Traumatized Alveolar Bone Defect with Recovery of Oral Functions Using Vertical Alveolar Distraction Osteogenesis and Immediate Loading Implant:A Case Report, J. Jpn. Soc. Oral Maxillofac. Trauma, Vol.22, No.1, 15-21, 2003. (Keyword) Distraction Osteogenesis / Alveolar Ridge Augmentation / Immediate Loading Implant
115.	Kenji Fujisawa, 住友孝史, 舘原誠晃, Youji Miyamoto, Nobuyuki Kamata and Masaru Nagayama : 下顎骨関節突起骨折の臨床的検討, Journal of the Japanese Society for the Temporomandibular Joint, Vol.15, No.1, 18-23, 2003. (Keyword) condylar fracture of the mandible / clinical study / clinical outcome (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1390282679397933440 (CiNii: 1390282679397933440)
116.	Seiko Tatehara, Youji Miyamoto, Kenji Fujisawa, Masaaki Takechi, Yukihiro Momota, Tetsuya Yuasa, Masaru Nagayama and Eiji Yamauchi : Use Experience with an Implant-Type Distractor for Vertical Alveolar Distraction Osteogenesis, Journal of Japanese Society of Oral Implantology, Vol.16, No.1, 91-96, 2003. (Keyword) distractor / distraction osteogenesis / alveolar ridge angmentation / osseointegrated implant
117.	Satake Hidetaka, Toyoaki Takagi, Shinya Horiuchi, Masahiko Yokozeki, Kenji Fujisawa, Youji Miyamoto, Hiroki Iga, Hideo Yoshida, Masaru Nagayama, Mitsunobu Sato and Keiji Moriyama : Clinical statistical study of jaw deformity patients at the Department of Orthodontics, Tokushima University Dental Hospital, Shikoku Dental Research, Vol.15, No.2, 257-262, 2003.
118.	Kenji Fujisawa, Youji Miyamoto, Nobuyuki Kamata, Masaru Nagayama and Fumihiro Matsumoto : クローズドロックに対するパンピング·マニピュレーション，上関節腔洗浄療法について, Shikoku Dental Research, Vol.15, No.2, 243-250, 2003.
119.	Youji Miyamoto, Kenji Fujisawa, Masaaki Takechi, Yukihiro Momota, Masaru Nagayama, Eiji Yamauchi, Eiichi Bando and Daisuke Hinode : Evaluation of Clinical Factors Conserning Osseointegration Establishment of a Dental Implant, Journal of Japanese Society of Oral Implantology, Vol.15, No.4, 436-445, 2002. (Keyword) dental implant / early failure / osseointegration / clinical factor (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1390282680486990592 (CiNii: 1390282680486990592)
120.	Masaaki Takechi, Youji Miyamoto, Yukihiro Momota, Tetsuya Yuasa, Seiko Tatehara, Masaru Nagayama, Kunio Ishikawa and Kasuomi Suzuki : The in vitro antibiotic release from anti-washout apatite cement using chitosan, Journal of Materials Science. Materials in Medicine, Vol.13, No.10, 973-978, 2002. (Summary) The in vitro antibiotic release from anti-washout apatite cement using chitosan (aw-AC(chi)) was investigated in a preliminary evaluation. Flomoxef sodium was employed as the antibiotic and was incorporated into the powder phase aw-AC(chi) at up to 10%. The setting times were measured for aw-AC(chi) containing various amounts of flomoxef sodium. X-ray diffraction (XRD) analysis was also conducted for the identification of products. To evaluate the drug release profile, set aw-AC was immersed in saline and the released flomoxef sodium was determined at regular intervals. The setting time was prolonged slightly with the addition of flomoxef sodium. The difference at 10% flomoxef sodium (0% vs. 10%) was not significant (p>0.05), and can be negligible in clinic. The XRD analysis revealed that formation of hydroxyapatite (HAP) from aw-AC(chi) was reduced, even after 24 h, when the aw-AC(chi) contained flomoxef sodium at 8% or more. The flomoxef sodium release from aw-AC(chi) showed the typical profile observed in skeleton type drug delivery system (DDS). Changing the concentration of chitosan can control the rate of drug release from aw-AC. Therefore, we conclude that aw-AC(chi) is a good candidate for potential use as a DDS carrier that may be useful in surgical operations. (Link to Publication Site) ● Publication site (DOI): 10.1023/A:1019816830793 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 15348192 ● Search Scopus @ Elsevier (PMID): 15348192 ● Search Scopus @ Elsevier (DOI): 10.1023/A:1019816830793 (DOI: 10.1023/A:1019816830793, PubMed: 15348192)
121.	Masayuki Kon, Hirakata Mayumi Luciana, Youji Miyamoto, Fumiaki Kawano and Kenzo Asaoka : Surface-layer modification of hydroxyapatite ceramic with acid and heat treatments, Dental Materials Journal, Vol.21, No.2, 170-180, 2002. (Summary) The purpose of this study was to examine or characterize the surface layer of a calcium phosphate ceramic with a gradual compositional change from alpha-tricalcium phosphate (alpha-TCP) on the surface to hydroxyapatite (HAP) on the inside. The surface of a dense HAP ceramic was acid-treated for 1 hour with orthophosphoric acid (H3PO4) solutions of several concentrations (0.5, 1.0 and 5.0 mol/L) or a buffered solution (pH 4.0) consisting of phosphate solutions. After acid treatment, specimens were heat-treated at 1,250 degrees C for 1 hour. X-ray photoelectron spectroscopy revealed that the compositional gradient layer could be modified on the surface of the HAP ceramic with all acid and heat treatments, and that 5.0 mol/L H3PO4 solution and heat treatments had a maximal thickness of approximately 2 microm for the surface-modified layer. It was confirmed that the outermost layer of HAP ceramics modified with the treatments, except 5.0 mol/L H3PO4 solution, showed a compound such alpha-TCP. (Keyword) Apatite ceramic / Surface treatment / α-Tricalcium phosphate (Link to Publication Site) ● Publication site (DOI): 10.4012/dmj.21.170 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 12238785 ● CiNii @ National Institute of Informatics (CRID): 1390282679692695424 ● Search Scopus @ Elsevier (PMID): 12238785 ● Search Scopus @ Elsevier (DOI): 10.4012/dmj.21.170 (DOI: 10.4012/dmj.21.170, PubMed: 12238785, CiNii: 1390282679692695424)
122.	Kenichi Hamada, Masayuki Kon, Takao Hanawa, Ken'ichi Yokoyama, Youji Miyamoto and Kenzo Asaoka : Hydrothermal modification of titanium surface in calcium solutions, Biomaterials, Vol.23, No.10, 2265-2272, 2002. (Summary) Hydrothermal modification of a titanium surface in calcium solutions was performed. The apatite precipitation on the modified surface in Hanks' solution, as a simulated body fluid, was evaluated and the surface microstructure changes after the modification were characterized by thin-film X-ray diffractometry (TF-XRD) and X-ray photoelectron spectroscopy (XPS). Hydrothermal modification in CaO solution enhanced the precipitation of apatite on the titanium surface. High pH, high pressure and high temperature of the CaO solution increased the thickness of the surface-modified layer and enhanced the synthesis of calcium titanate which possibly promoted the precipitation of apatite in Hanks' solution. Hydrothermal modification in CaCl2 solution, on the other hand, showed reverse effects. The modification of titanium in CaO solution with hydrothermal treatment is expected to result in excellent osteointegration and can be easily performed by using an autoclave, a clinical apparatus widely used. (Keyword) Apatites / Body Fluids / Bone and Bones / calcium / Calcium Chloride / Chemical Precipitation / Electron Probe Microanalysis / Hydrogen-Ion Concentration / Microscopy, Electron, Scanning / Models, Chemical / Oxygen / pressure / temperature / titanium / Water / X-ray diffraction (Link to Publication Site) ● Publication site (DOI): 10.1016/S0142-9612(01)00361-1 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 11962668 ● Search Scopus @ Elsevier (PMID): 11962668 ● Search Scopus @ Elsevier (DOI): 10.1016/S0142-9612(01)00361-1 (DOI: 10.1016/S0142-9612(01)00361-1, PubMed: 11962668)
123.	Kunio Ishikawa, Youji Miyamoto, Tetsuya Yuasa, Atsuo Ito, Masaru Nagayama and Kazuomi Suzuki : Fabrication of Zn containing apatite cement and its initial evaluation using human osteoblastic cells, Biomaterials, Vol.23, No.2, 423-428, 2002. (Summary) Recently, the effects of Zn2+ on osteogenesis stimulation have become major topics in the research fields of bone formation and organism essential elements. Based on the fundamental finding of Zn2+ with respect to osteogenesis stimulation, Ito et al. have prepared Zn doped beta-tricalcium phosphate (ZnTCP) and have reported that ZnTCP enhances the proliferation of MC3T3-E1 cells. In this investigation, we studied the effects of ZnTCP added to apatite cement (AC) with respect to its setting reaction and proliferation of human osteoblastic cells as an initial evaluation for the feasibility of AC containing ZnTCP. Compositional analysis using powder X-ray diffractometer revealed that ZnTCP shows no reactivity with the setting reaction of AC. As a result, the mechanical strength of set AC decreased increasing amounts of added ZnTCP as if ZnTCP acts as a pore in AC. The setting time of AC was not affected by addition of ZnTCP up to 10%. When AC containing ZnTCP was immersed in alpha-MEM containing 10% bovine serum, Zn2+ was released from AC. Larger amounts of Zn2+ were released from AC containing larger amounts of ZnTCP. When human osteoblastic cells were incubated on the surface of AC discs, proliferation of human osteoblastic cells was significantly increased on the surface of AC that contained 5% ZnTCP when compared with that containing no ZnTCP. In contrast, proliferation of human osteoblastic cells decreased on the surface of AC that contained 10% ZnTCP when compared with that free from ZnTCP; indicating cytotoxicity. We concluded therefore, that addition of ZnTCP to AC is useful to enhance the osteoconductivity of AC when release of Zn2+ can be carefully regulated. (Keyword) ZnTCP / Apatite cement / Osteoblasts / Proliferation (Link to Publication Site) ● Publication site (DOI): 10.1016/S0142-9612(01)00121-1 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 11761162 ● CiNii @ National Institute of Informatics (CRID): 1571417126705406208 ● Search Scopus @ Elsevier (PMID): 11761162 ● Search Scopus @ Elsevier (DOI): 10.1016/S0142-9612(01)00121-1 (DOI: 10.1016/S0142-9612(01)00121-1, PubMed: 11761162, CiNii: 1571417126705406208)
124.	Masaaki Takechi, Youji Miyamoto, Kunio Ishikiawa, Yukihiro Momota, Tetsuya Yuasa, Seiko Tatehara, Kazuomi Suzuki and Masaru Nagayama : Effects of powder phase sterilization on basic properties of apatite cement, Key Engineering Materials, Vol.218-220, 339-342, 2002. (Keyword) Apatite Cement / Hydroxyapatite / γ-Ray Irradiation (Link to Search Site for Scientific Articles) ● Summary page in Scopus @ Elsevier: 2-s2.0-0036166816 (Elsevier: Scopus)
125.	Yukihiro Momota, Youji Miyamoto, Kunio Ishikawa, Masaaki Takechi, Tetsuya Yuasa, Seiko Tatehara, Masaru Nagayama and Kazuomi Suzuki : Evaluation of Feasibility of Hydroxyapatite Putty as a Local Hemostatic Agent for Bone., Journal of Biomedical Materials Research, Vol.63, No.5, 542-547, 2002. (Summary) Although bone wax is known to cause an inflammatory reaction in soft tissue and a delay of bone healing, it is usually the first choice to arrest bleeding from bone. Hydroxyapatite (HAP) putty is proposed here. This study evaluated the feasibility of HAP putty with respect to whether or not it has potential value as a hemostatic agent for bone. First, the adhesive strength of HAP putty to bone was evaluated. The adhesive strength of HAP putty to wet bone was much higher when compared with that of bone wax, even though the adhesive strengths of HAP putty and bone wax to dry bone were equivalent. Next, to evaluate the hemostatic ability of HAP putty, bony defects were made in rabbits. HAP putty could arrest bleeding from bone within 3 min. However, when the hemostasis was performed with bone wax, bleeding was arrested within 8 min. Thus, HAP putty showed better hemostatic ability than bone wax. Finally, the tissue response to HAP putty in rabbit subcutaneous tissue was evaluated. Histological observation revealed a slight inflammatory response around HAP putty, whereas bone wax was surrounded by moderate inflammatory tissue. In conclusion, HAP putty has good potential value to be a hemostatic agent for bone because it has strong adhesion, good hemostatic ability, and biocompatibility. (Keyword) hemostatic agents / hydroxyapatite putty / bone wax / apatite cement, calcium phosphate cement (Link to Publication Site) ● Publication site (DOI): 10.1002/jbm.10332 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 12209899 ● Search Scopus @ Elsevier (PMID): 12209899 ● Search Scopus @ Elsevier (DOI): 10.1002/jbm.10332 (DOI: 10.1002/jbm.10332, PubMed: 12209899)
126.	Masaaki Takechi, Kunio Ishikawa, Youji Miyamoto, Masaru Nagayama and Kazuomi Suzuki : Tissue responses to anti-washout apatite cement using chitosan when implanted in the rat tibia, Journal of Materials Science. Materials in Medicine, Vol.12, No.7, 597-602, 2001. (Summary) The tissue response to anti-washout apatite cement using chitosan (aw-AC(chi)) was evaluated by implanting aw-AC(chi) into bone defects of rat tibiae using conventional apatite cement (c-AC) as a control material. During the experimental period up to 16 weeks, the only difference between aw-AC and c-AC was found at two weeks in the tissue response of soft tissue. At two weeks, c-AC showed a moderate inflammatory response; small particles of c-AC were scattered in the cutaneous tissue and many foreign body giant cells were collected around the scattered c-AC, whereas aw-AC showed only a slight inflammatory response and few foreign body giant cells. We found no difference between aw-AC(chi) and c-AC with respect to bone tissue response. Both AC were almost completely surrounded by mature bone at eight weeks. No promotion or reduction of osteoconductivity was observed by chitosan even though it is considered to promote bone formation. We concluded, therefore, that enhancement of bone formation cannot be expected by employing chitosan to obtain anti-washout properties, at least in the concentration used in this study, even though aw-AC(chi) is much more useful than c-AC. (Link to Publication Site) ● Publication site (DOI): 10.1023/A:1011285509391 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 15348252 ● Summary page in Scopus @ Elsevier: 2-s2.0-0034928206 (DOI: 10.1023/A:1011285509391, PubMed: 15348252, Elsevier: Scopus)
127.	Youji Miyamoto, Taketomo Toh, Kunio Ishikawa, Tetsuya Yuasa, Masaru Nagayama and Kazuomi Suzuki : Effect of added NaHCO₃ on the basic properties of apatite cement, Journal of Biomedical Materials Research, Vol.54, No.3, 311-319, 2001. (Summary) Alternation of a composition of set apatite cement (AC) from carbonate-free apatite (CO3-free AP) to carbonate apatite (CO3-AP) may accelerate replacement of the set AC with bone because CO3-AP can be dissolved much faster than CO3-free AP in the weak acidic solution produced by osteoclasts. In this investigation, NaHCO3 was added to the AC component and the effects of added NaHCO3 on cement-setting behavior and on set mass were studied as an initial step for the fabrication of AC, which can be replaced with bone faster than current AC. When NaHCO3 was added to AC, the resultant set mass contained CO3. Although not all CO3 was incorporated in the set AC, the amount of CO3 incorporated into the set AC increased with the amount of added NaHCO3. Powder X-ray diffraction analysis and Fourier transform infrared spectrometer measurements revealed the formation of B-type CO3-AP. The setting time measured in an incubator at 37 degrees C and 100% relative humidity slowed from 30 to 45 min, indicating that NaHCO3 has an inhibitory effect on AP formation. The diametral tensile strength of the set AC decreased significantly with the addition of NaHCO3. Scanning electron microscopic observation revealed that fine crystals were formed in the set AC when NaHCO3 was added to AC. As a result, the crystallinity indices of the set AC measured using X-ray diffraction and Fourier transform infrared spectroscopy decreased with an increase in the amount of added NaHCO3. The dissolution rate of set AC in weak acid, pH 5.5, increased with the amount of added NaHCO3. We concluded that the formation of B-type CO3-AP and the resulting faster dissolution of set AC in weak acidic solution is preferable for the faster replacement of set AC with bone even though the decreased diametral tensile strength value is a shortcoming. (Keyword) apatite cement / calcium phosphate cement / carbonate apatite / hydroxyapatite / NaHCO₃ (Link to Publication Site) ● Publication site (DOI): 10.1002/1097-4636(20010305)54:3<311::AID-JBM10>3.0.CO;2-H (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 11189035 ● Summary page in Scopus @ Elsevier: 2-s2.0-0035809306 (DOI: 10.1002/1097-4636(20010305)54:3<311::AID-JBM10>3.0.CO;2-H, PubMed: 11189035, Elsevier: Scopus)
128.	Tetsuya Yuasa, Youji Miyamoto, Kunio Ishikiawa, Masaaki Takechi, Masaru Nagayama and Kazuomi Suzuki : In vitro resorption of three apatite cements with osteoclasts, Journal of Biomedical Materials Research, Vol.54, No.3, 344-350, 2001. (Summary) To evaluate the replacement of apatite cement (AC) with bone, osteoclasts were incubated for 48 h on the surface of three AC types: conventional AC (c-AC), fast-setting AC (fs-AC), and anti-washout AC (aw-AC), using sintered apatite (AP) and cortical bone as control materials. We found osteoclasts attached to the surface of AC and osteoclastic resorption pits after 48 h of incubation for all experimental AC types. In contrast, no resorption pit was observed on the surface of sintered AP although osteoclasts were attached to the surface of sintered AP. There was no significant difference among the types of AC with respect to the resorption area, but the resorption areas were only approximately 1% of that on the surface of cortical bone. We concluded, therefore, that ACs could be replaced with bone regardless of the type but that it takes extensive time for the ACs to be completely replaced with bone. (Keyword) apatite cement / calcium phosphate cement / hydroxyapatite / osteoclasts / resorption (Link to Publication Site) ● Publication site (DOI): 10.1002/1097-4636(20010305)54:3<344::AID-JBM50>3.0.CO;2-1 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 11189039 ● Summary page in Scopus @ Elsevier: 2-s2.0-0035809842 (DOI: 10.1002/1097-4636(20010305)54:3<344::AID-JBM50>3.0.CO;2-1, PubMed: 11189039, Elsevier: Scopus)
129.	Satoru Tobiume, Kenji Fujisawa, Hiroaki Nakanishi, Eiji Hayashi, Youji Miyamoto and Masaru Nagayama : A case of first and second branchial arch syndrome in a patient whose profile and occlusion improved in response to orthognatic surgery, Japanese Journal of Oral & Maxillofacial Surgery, Vol.46, No.2, 96-98, 2000. (Summary) We describe a case of first and second branchial arch syndrome in a patient whose profile and occlusion improved in response to orthognatic surgery.<BR>A 2-year-9-month-old boy was referred to our clinic for the treatment of open bite. Because symptoms were mild the patient was placed under observation. However, open bite and bird face became severer as he grew older. Cephalometric analysis indicated mandibular micrognathia. Before operation, we made and analyzed computer tomography-based three-dimensional models. The models were very useful for operation planning. After preoperative orthodontic treatment, sagittal splitting ramus osteotomy and horizontal sliding advancement genioplasty were performed in two stages. (Keyword) first and second branchial arch syndrome / orthognatic surgery (Link to Publication Site) ● Publication site (DOI): 10.5794/jjoms.46.96 (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1390001206529016704 ● Search Scopus @ Elsevier (DOI): 10.5794/jjoms.46.96 (DOI: 10.5794/jjoms.46.96, CiNii: 1390001206529016704)
130.	Kenji Fujisawa, Hiroaki Nakanishi, Youji Miyamoto, 宮本悦子, 野田純子, 林英司, Masaru Nagayama, 島川清司, 阿部秀吉 and 森瞬次 : 徳島県立ひのみね整肢医療センター歯科における心身障害児(者)の診療実態について, Shikoku Dental Research, Vol.12, No.2, 269-275, 2000. (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1573950400938250112 (CiNii: 1573950400938250112)
131.	Youji Miyamoto, Kunio Ishikawa, Masaaki Takechi, Taketomo Toh, Tetsuya Yuasa, Masaru Nagayama and Kazuomi Suzuki : Histological and compositional evaluations of three types of calcium phosphate cements when implanted in subcutaneous tissue immediately after mixing, Journal of Biomedical Materials Research, Vol.48, No.1, 36-42, 1999. (Summary) To evaluate the soft tissue response of calcium phosphate cement (CPC), consisting of an equimolar mixture of tetracalcium phosphate (TTCP) and dicalcium phosphate anhydrous (DCPA) under conditions close to those encountered in actual surgical procedures, we implanted three types of CPC [conventional CPC (c-CPC), fast-setting CPC (FSCPC), and antiwashout type FSCPC (aw-FSCPC; formerly called nondecay type FSCPC or nd-FSCPC)] subcutaneously in the abdomens of rats immediately (1 min) after mixing. At 1 week after surgery, histological examination and compositional analysis were performed using light microscopy and powder X-ray diffraction (XRD), respectively. The implanted c-CPC was crumbled completely, whereas FSCPC and aw-FSCPC retained their shape. Large vesicles containing copious inflammatory effusion were subcutaneously formed around the c-CPC. Histologically, many foreign-body giant cells were collected around the c-CPC, and moderate inflammatory cell infiltration was observed at 1 week after surgery. In contrast, the FSCPC and aw-FSCPC were covered with a thin layer of granulation tissue that included few giant cells and presented slight inflammatory cell infiltration, and no effusion was observed. The XRD analysis of the c-CPC revealed the presence of some unreacted DCPA even 1 week after implantation, whereas almost no DCPA was found in the FSCPC or aw-FSCPC. In conclusion, it was found that CPC does not always show excellent tissue response. When c-CPC is implanted subcutaneously in rats immediately after mixing, it fails to set and causes a severe inflammatory response. Therefore, the type of CPC should be chosen according to the clinical particulars. CPC should be used in a manner that assures its setting reaction. We recommend the use of FSCPC and aw-FSCPC for surgical applications, such as orthopedics, plastic and reconstructive surgery, and oral and maxillofacial surgery, where the cement might otherwise crumble due to the pressure before setting. (Keyword) Animals / Biocompatible Materials / Bone Cements / Calcium Phosphates / Foreign Bodies / Granuloma / Male / Prostheses and Implants / Rats / Rats, Wistar / skin / Skin Diseases (Link to Publication Site) ● Publication site (DOI): 10.1002/(sici)1097-4636(1999)48:1%3C36::aid-jbm8%3E3.0.co;2-i (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 10029148 ● Search Scopus @ Elsevier (PMID): 10029148 ● Search Scopus @ Elsevier (DOI): 10.1002/(sici)1097-4636(1999)48:1%3C36::aid-jbm8%3E3.0.co;2-i (DOI: 10.1002/(sici)1097-4636(1999)48:1%3C36::aid-jbm8%3E3.0.co;2-i, PubMed: 10029148)
132.	Michiyo Kuwahara, Kikuji Yamashita, Youji Miyamoto, Fumio Nasu and Hiroshi Ishizuka : Ultrastructures of the sublingual and interpapillar surface of the human tongue, Japanese Journal of Oral Biology, Vol.41, 11-20, 1999. (Keyword) human tongue / ultrastructure / sublingual epithelium / interpapillar epithelium / microridge
133.	Masaaki Takechi, Youji Miyamoto, Kunio Ishikawa, Masaru Nagayama, Masayuki Kon, Kenzo Asaoka and Kazuomi Suzuki : Effects of added antibiotics on the basic properties of anti-washout-type fast-setting calcium phosphate cements, Journal of Biomedical Materials Research, Vol.39, No.2, 308-316, 1998.
134.	Youji Miyamoto, Kenji Fujisawa, Masaaki Takechi, Kozaburo Nakano, Masaru Nagayama, Atsushi Suzuki, Takashi Ikeda, Eiichi Bando and Daisuke Hinode : Three Cases of Application of Osseointegrated Implant to Surgical Reconstructive Area in Oral Cancer Patients, --- Discussion of the Management of Reconstructive Soft Tissue Surrounding Implants ---, Journal of Japanese Society of Oral Implantology, Vol.11, No.2, 69-77, 1998.
135.	Masayuki Kon, Youji Miyamoto, Kenzo Asaoka, Kunio Ishikiawa and Hae-Hyoung Lee : Development of calcium phosphate cement for rapid crystallization to apatite, Dental Materials Journal, Vol.17, No.4, 223-232, 1998.
136.	Youji Miyamoto, Kunio Ishikawa, Masaaki Takechi, Taketomo Toh, Tetsuya Yuasa, Masaru Nagayama and Kazuomi Suzuki : Basic properties of calcium phosphate cement containing atelocollagen in its liquid or powder phases, Biomaterials, Vol.19, 707-715, 1998.
137.	Masaaki Takechi, Youji Miyamoto, Kunio Ishikiawa, Taketomo Toh, Tetsuya Yuasa, Masaru Nagayama and Kazuomi Suzuki : Initial histological evaluation of anti-washout type fast-setting calcium phosphate cement following subcutaneous implantation, Biomaterials, Vol.19, 2057-2063, 1998.
138.	Takao Hanawa, Masayuki Kon, Hidemi Ukai, Kouichi Murakami, Youji Miyamoto and Kenzo Asaoka : Surface modification of titanium in calcium-ion-containing solutions, Journal of Biomedical Materials Research, Vol.34, No.3, 273-278, 1997.
139.	Kunio Ishikiawa, Youji Miyamoto, Masaaki Takechi, Taketomo Toh, Masayuki Kon, Masaru Nagayama and Kenzo Asaoka : Non-decay type fast-setting calcium phosphate cement: Hydroxyapatite putty containing an increased amount of sodium alginate, Journal of Biomedical Materials Research, Vol.36, No.3, 393-399, 1997.
140.	Kunio Ishikawa, Youji Miyamoto, Masaru Nagayama and Kenzo Asaoka : Blast coating method: New method of coating titanium surface with hydroxyapatite at room temperature, Journal of Biomedical Materials Research, Vol.38, No.2, 129-134, 1997.
141.	Youji Miyamoto, Kunio Ishikawa, Masaaki Takechi, Taketomo Toh, Yuki Yoshida, Masaru Nagayama, Masayuki Kon and Kenzo Asaoka : Tissue response to fast-setting calcium phosphate cement in bone, Journal of Biomedical Materials Research, Vol.37, No.4, 457-464, 1997.
142.	Youji Miyamoto, Kenji Fujisawa, Masaru Nagayama, Norio Haneji and Yoshio Hayashi : Carcinoma in Pleomorphic Adenoma of the Tongue ; Report of a case, Oral Medicine & Pathology, Vol.1, No.2, 111-114, 1996. (Summary) A carcinoma in pleomorphic adenoma occurring in the tongue of a 47-year-old Japanese woman is reported. The present report is the first to describe a carcinoma in pleomorphic adenoma derived from the posterior lingual glands. (Keyword) carcinoma in pleomorphic adenoma / lingual gland / malignant mixed tumor / pleomorphic adenoma / tongue (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1570009752234590720 (CiNii: 1570009752234590720)
143.	Youji Miyamoto, Masaru Nagayama and Yoshio Hayashi : Verruciform xanthoma occurring within oral lichen planus, Journal of Oral Pathology & Medicine, Vol.25, No.4, 188-191, 1996.
144.	Youji Miyamoto, Kunio Ishikawa, Masaaki Takechi, Masayuki Kon, Masaru Nagayama and Kenzo Asaoka : Non-decay type fast-setting calcium phosphate cement: setting behaviour in calf serum and its tissue response, Biomaterials, Vol.17, 1429-1435, 1996.
145.	Youji Miyamoto, Kunio Ishikawa, Masaaki Takechi, Masayuki Kon, Masaru Nagayama and Kenzo Asaoka : Soft tissue response of calcium phosphate cements, Bioceramics, Vol.9, 263-266, 1996.
146.	Masaaki Takechi, Youji Miyamoto, Kunio Ishikiawa, Masayuki Kon, Masaru Nagayama and Kenzo Asaoka : Basic properties of hydroxyapatite putty made with fast-setting calcium phosphate cement and sodium alginate, Bioceramic, Vol.9, 235-238, 1996.
147.	Masaaki Takechi, Youji Miyamoto, Kunio Ishikawa, Masaru Nagayama, Masayuki Kon and Kenzo Asaoka : Non-decay type fast-setting calcium phosphate cement using chitosan, Journal of Materials Science Materials in Medicine, Vol.7, No.6, 317-322, 1996.
148.	Kunio Ishikawa, Youji Miyamoto, Masayuki Kon, Masaru Nagayama and Kenzo Asaoka : Non-decay type fast-setting calcium phosphate cement, --- : Composite with sodium alginate ---, Biomaterials, Vol.16, No.7, 527-432, 1995.
149.	Masayuki Kon, Kunio Ishikawa, Youji Miyamoto and Kenzo Asaoka : Development of calcium phosphate based functional gradient bioceramics, Biomaterials, Vol.16, No.9, 709-714, 1995.
150.	Youji Miyamoto, Kunio Ishikawa, Hirokazu Fukao, Masahiro Sawada, Masaru Nagayama, Masayuki Kon and Kenzo Asaoka : In vivo setting behavior of fast-setting calcium phosphate cement, Biomaterials, Vol.16, No.11, 855-860, 1995. (Summary) The in vivo setting behaviour of fast-setting calcium phosphate cement (FSCPC) between femoral muscles of the rat was investigated to evaluate the possible value of FSCPC for medical and dental application. Conventional CPC (c-CPC) and FSCPC were implanted between femoral muscles, and various aspects of the setting behaviour such as setting time, mechanical strength and conversion ratio of cement into hydroxyapatite (HAP: Ca10(PO4)6(OH)2) were measured by the Vicat needle method, diametral tensile strength (DTS) measurement, and quantitative powder X-ray diffraction (XRD) analysis, respectively. The setting time of FSCPC in vivo was 5-7 min, in contrast to 48 min for c-CPC. As a result of its fast setting, set specimens of FSCPC showed higher mechanical strength from the initial stage than c-CPC. Higher DTS values were observed in FSCPC than c-CPC implanted after 24 h. Powder XRD analysis revealed faster conversion of FSCPC than c-CPC into HAP, which was responsible both for the faster setting and higher mechanical strength from the initial stage. We concluded, therefore, that FSCPC may be used for a wide range of clinical applications, i.e. fields where fast setting is required such as orthopaedic, plastic and reconstructive, and oral and maxillofacial surgery. (Keyword) Animals / Biocompatible Materials / Bone Cements / Calcium Phosphates / Durapatite / Femur / Male / Muscle, Skeletal / Prostheses and Implants / Rats / Rats, Wistar / Tensile Strength / X-ray diffraction (Link to Publication Site) ● Publication site (DOI): 10.1016/0142-9612(95)94147-D (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 8527601 ● Search Scopus @ Elsevier (PMID): 8527601 ● Search Scopus @ Elsevier (DOI): 10.1016/0142-9612(95)94147-D (DOI: 10.1016/0142-9612(95)94147-D, PubMed: 8527601)
151.	Kazuhito Satomura, 力丸浩一, 林英司, 野沢孝行, Youji Miyamoto and Masaru Nagayama : 過去10年間のガマ腫39症例の臨床的検討, Journal of The Japanese Stomatological Society, Vol.44, No.2, 261-264, 1995.
152.	Kazuhito Satomura, 板東泰博, 林英司, Youji Miyamoto and Masaru Nagayama : 維持透析患者に生じた舌癌の1治験例, Japanese Journal of Oral & Maxillofacial Surgery, Vol.40, No.9, 1009-1011, 1994.
153.	Youji Miyamoto, 滝下幸夫, 林英司, Masaru Nagayama, 東富雄, Yoshio Hayashi, 高橋敬治 and 宇山正 : 顎下腺と肺の重複癌の1例, 日本口腔腫瘍学会誌, Vol.4, No.2, 264-269, 1992.
154.	Shinya Kawata, Eiji Hayashi, Youji Miyamoto, Masaru Nagayama, Hiroyo Deguchi, Tomio Azuma and Yoshio Hayashi : Four cases of cementifying fibroma, Japanese Journal of Oral & Maxillofacial Surgery, Vol.38, No.3, 479-485, 1992.
155.	Eiji Hayashi, Akio Hori, Youji Miyamoto, Masaru Nagayama, Hiroyo Deguchi and Yoshio Hayashi : Lung carcinoma suspected to metastarize to the submandibular region by the autopsy, --- Report of a case ---, Japanese Journal of Oral & Maxillofacial Surgery, Vol.38, No.4, 679-680, 1992.
156.	Youji Miyamoto, Masaru Nagayama and Yoshio Hayashi : A Cleft Child With Lobulated Tongue and Lingual Hamartoma: Report of a Case, Journal of Oral and Maxillofacial Surgery, Vol.49, No.6, 644-646, 1991. (Keyword) Cleft Palate / Female / Hamartoma / Humans / Infant / Tongue / Tongue Neoplasms (Link to Publication Site) ● Publication site (DOI): 10.1016/0278-2391(91)90348-P (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 2037922 ● Search Scopus @ Elsevier (PMID): 2037922 ● Search Scopus @ Elsevier (DOI): 10.1016/0278-2391(91)90348-P (DOI: 10.1016/0278-2391(91)90348-P, PubMed: 2037922)
157.	Youji Miyamoto, Fumihiro Matsumoto, Yukio Takishita, Masaru Nagayama, Hiroyo Deguchi and Yoshio Hayashi : Solitary neurofibroma of the tongue: Report of a case, Japanese Journal of Oral & Maxillofacial Surgery, Vol.37, No.6, 1187-1188, 1991.
158.	Fumihiro Matsumoto, Youji Miyamoto and Masaru Nagayama : Light-and Electron-Microscopic Observations on the Mandibular Condylar Cartilages in Growing Rats on a Low-Calcium Diet, Acta Anatomica, Vol.142, No.1, 41-48, 1991. (Summary) In order to obtain more insight into the physiologic mechanism of endochondral ossification, histological changes occurring in the mandibular condylar cartilage of growing rats fed on a low-calcium diet were investigated by light and electron microscopy. Twenty-three-day-old rats were fed on a normal diet or a low-calcium diet for 8 weeks. For the histological observations the mandibular condyles were dissected from each animal at 1, 2, 4, 5 and 8 weeks after the initiation of the experiment. Histological changes occurring in the mandibular condylar cartilages of the rats fed on a low-calcium diet were as follows: (1) narrow proliferative and mature cell zones and a wide hypertrophic cell zone, (2) inhibition of development of cell organelles in the mature chondrocytes, (3) decrease in dead cells in the proliferative zone, (4) decrease in glycogen accumulation in the chondrocytes and (5) inhibition of calcification in the extracellular matrix of the hypertrophic cell zone. Additionally at the end of the experimental period, the following findings were observed: (1) appearance of small light cells in the mature cell zone and the hypertrophic cell zone and (2) decrease in proteoglycan granules and appearance of large collagen fibrils in the pericellular region of the hypertrophic cell zone. (Keyword) Animals / Bone Development / Calcium, Dietary / Cartilage, Articular / Collagen / Diet / Male / Mandible / Organelles / Rats / Rats, Inbred Strains (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 1781238 ● Search Scopus @ Elsevier (PMID): 1781238 (PubMed: 1781238)
159.	Youji Miyamoto, 安田勝裕, 林英司, Kenji Fujisawa, 川田真也, 原友則 and Masaru Nagayama : 当科における5年間の小児入院患者の臨床統計的観察, 小児口腔外科, Vol.1, No.2, 111-117, 1991.
160.	Kenji Fujisawa, Hiroaki Nakanishi, Kazuhito Satomura, 安田勝裕, Youji Miyamoto, Masaru Nagayama, 出口博代 and Yoshio Hayashi : 石灰化歯原性嚢胞の3例, Journal of The Japanese Stomatological Society, Vol.40, No.4, 900-911, 1991.
161.	Youji Miyamoto, Masaru Nagayama and Tomomichi Takagi : マウス(BALB/c)二次口蓋突起癒合に関する研究, Acta Anatomica Nipponica, Vol.62, No.1, 5-18, 1987.
162.	Tomomichi Takagi, Kazuyoshi Nishikawa, Noboru Kanematsu, Youji Miyamoto and Hideo Tsutsui : On the double relief pattern of incisors and the central tubercles of premolars, Japanese Journal of Oral Biology, Vol.28, No.6, 752-756, 1986.
163.	喜多孝志, 佐藤圭, 河田耕治, 吉成美予, 兼松登, 岩目益芳, 福田望, 安田勝裕, Youji Miyamoto, 佐藤純, 椋本稔敏 and 吉田幸子 : 口腔悪性腫瘍に対するPepleomycin使用についての臨床的検討, Japanese Journal of Oral & Maxillofacial Surgery, Vol.31, No.8, 1911-1916, 1985.

Academic Paper (Unrefereed Paper):

1.	Youji Miyamoto, Naoyuki Fukuda and Keiko Kudoh : The Current Situation of Carbonate Apatite as a Noble Bone Substitute and Its Future Development in the Oral Region, Journal of Japanese Society of Oral Implantology, Vol.35, No.4, 268-275, 2022. (Keyword) bone augmentation / bone substitute / bone regenerative medicine / carbonate apatite / hydroxyapatite (Tokushima University Institutional Repository) ● Metadata: 117953 (Link to Publication Site) ● Publication site (DOI): 10.11237/jsoi.35.268 (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1390857899425066624 ● Search Scopus @ Elsevier (DOI): 10.11237/jsoi.35.268 (Tokushima University Institutional Repository: 117953, DOI: 10.11237/jsoi.35.268, CiNii: 1390857899425066624)
2.	K Ishikawa, Youji Miyamoto, A Tsuchiya, K Hayashi, K Tsuru and Go Ohe : Physical and Histological Comparison of Hydroxyapatite, Carbonate Apatite, and -Tricalcium Phosphate Bone Substitutes., Materials, Vol.11, No.10, 2018. (Summary) Three commercially available artificial bone substitutes with different compositions, hydroxyapatite (HAp; Neobone), carbonate apatite (CO3Ap; Cytrans), and β-tricalcium phosphate (β-TCP; Cerasorb), were compared with respect to their physical properties and tissue response to bone, using hybrid dogs. Both Neobone (HAp) and Cerasorb (β-TCP) were porous, whereas Cytrans (CO3Ap) was dense. Crystallite size and specific surface area (SSA) of Neobone (HAp), Cytrans (CO3Ap), and Cerasorb (β-TCP) were 75.4 ± 0.9 nm, 30.8 ± 0.8 nm, and 78.5 ± 7.5 nm, and 0.06 m²/g, 18.2 m²/g, and 1.0 m²/g, respectively. These values are consistent with the fact that both Neobone (HAp) and Cerasorb (β-TCP) are sintered ceramics, whereas Cytrans (CO3Ap) is fabricated in aqueous solution. Dissolution in pH 5.3 solution mimicking Howship's lacunae was fastest in CO3Ap (Cytrans), whereas dissolution in pH 7.3 physiological solution was fastest in β-TCP (Cerasorb). These results indicated that CO3Ap is stable under physiological conditions and is resorbed at Howship's lacunae. Histological evaluation using hybrid dog mandible bone defect model revealed that new bone was formed from existing bone to the center of the bone defect when reconstructed with CO3Ap (Cytrans) at week 4. The amount of bone increased at week 12, and resorption of the CO3Ap (Cytrans) was confirmed. β-TCP (Cerasorb) showed limited bone formation at week 4. However, a larger amount of bone was observed at week 12. Among these three bone substitutes, CO3Ap (Cytrans) demonstrated the highest level of new bone formation. These results indicate the possibility that bone substitutes with compositions similar to that of bone may have properties similar to those of bone. (Tokushima University Institutional Repository) ● Metadata: 115588 (Link to Publication Site) ● Publication site (DOI): 10.3390/ma11101993 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 30332751 ● Summary page in Scopus @ Elsevier: 2-s2.0-85054990038 (Tokushima University Institutional Repository: 115588, DOI: 10.3390/ma11101993, PubMed: 30332751, Elsevier: Scopus)
3.	Seiichiro Kitamura, Masami Ninomiya and Youji Miyamoto : カラーアトラス:皮膚・粘膜の下，透けて見えますか, Dental Outlook, Vol.10, No.6, 2007.
4.	Seiichiro Kitamura, Chihiro Shinohara and Youji Miyamoto : 歯科局所麻酔時に必要な解剖学の知識, 「見える! わかる! 臨床に役立つ解剖写真集 5」，歯界展望, Vol.101, No.5, 964-968, 2006.
5.	Youji Miyamoto, Kenji Fujisawa and Eiji Yamauchi : 口腔外科の視点からみた即時荷重インプラント, 補綴臨床別冊即時インプラント, 36-42, 2005.
6.	Youji Miyamoto : 歯科インプラントの安定性評価のための共鳴振動周波数分析装置「オステル」について, 日本歯科評論, Vol.63, No.11, 119-124, 2003.
7.	Masayuki Kon, Mayumi Luciana Hirakata, Youji Miyamoto and Kenzo Asaoka : Evaluation of bioceramics containing a-tricalcium phosphate, Archives of BioCeramics Research, Vol.3, 118-123, 2003.
8.	Mayumi Luciana Hirakata, Masayuki Kon, Tetsuya Yuasa, Youji Miyamoto and Kenzo Asaoka : Influences of crystal phases on bioactivity of calcium phosphate cements, Key Engineering Materials, Vol.218-220, 343-346, 2001.
9.	Youji Miyamoto, Kunio Ishikawa, Masaaki Takechi, Masayuki Kon, Masaru Nagayama and Kenzo Asaoka : Soft tissue responses of calcium phosphate cements, Bioceramics, Vol.9, 263-266, 1996.
10.	Masaaki Takechi, Youji Miyamoto, Kunio Ishikawa, Masayuki Kon, Masaru Nagayama and Kenzo Asaoka : Basic properties of hydroxyapatite putty made with fast-setting calcium phosphate cement and sodium alginate, Bioceramics, Vol.9, 235-238, 1996.
11.	Kunio Ishikawa, Youji Miyamoto, Masaaki Takechi, Taketomo Toh, Masayuki Kon, Masaru Nagayama and Kenzo Asaoka : Approaches for bone-replacing calcium phosphate cement, --- Effect of NaHCO3 addition on the properties of calcium phosphate cement ---, Bioceramics, Vol.9, 255-258, 1996.

Review, Commentary:

1.	Hiromichi Yumoto, Yoshiko Yamamura, Naozumi Ishimaru and Youji Miyamoto : Dd診断力てすと歯肉と頬粘膜の白色病変, デンタルダイアモンド, Vol.48, No.5, 25-26, Apr. 2023.
2.	Youji Miyamoto, Naoyuki Fukuda, Kazuya Akita, Keiko Kudoh and Naito Kurio : 骨補填材としての炭酸アパタイトの現状と今後の展開, Japanese Journal of MaxilloFacial Implants, Vol.20, No.2, 88-95, Aug. 2021. (Summary) A main inorganic component of human bone is not hydroxyapatite but carbonate apatite (CQ3Ap). Hydroxyapatite is not resorbed in the body but C03Ap can be resorbed and replaced with bone. We have succeeded in fabricating low crystalline CQ3Ap without sintering by dissolution-precipitation reaction using calcium hydroxide as a precursor. C03Ap showed excellent biocompatibility and faster bone formation compared to other bone substitutes (anorganic bovine bone and hydroxyapatite) in rabbit femur and dog mandible. Clinical study on effectiveness and safety of C03Ap granules in sinus floor augmentation was successfully concluded in 2016. CQ3Ap granules were approved by Japanese government in 2017, and marketed in 2018 as Cytrans® Granules. This comprehensive review explains the clinical cases of sinus lift and alveolar ridge augmentation of Cytrans® and its recommended clinical usage. Furthermore, we have succeeded in developing porous C03Ap and showed it was useful for reconstruction of mandibular bone defect in rabbit model and also aim to use it as a scaffold for bone regenerative medicine. (Keyword) apatite / bone substitute / bone regenerative medicine / carbonate apatite / アパタイト / 骨補填材 / 骨再生医療 / 炭酸アパタイト (Tokushima University Institutional Repository) ● Metadata: 116329 (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1010576118550922112 (Tokushima University Institutional Repository: 116329, CiNii: 1010576118550922112)
3.	Youji Miyamoto, Naito Kurio, Keiko Kudoh and Natsumi Takamaru : -, Journal of Japanese Society of Oral Implantology, Vol.34, No.1, 26-32, Mar. 2021. (Keyword) 歯科インプラント / 医療事故 / 手術手技 / dental implant / medical accident / operative procedure (Link to Publication Site) ● Publication site (DOI): 10.11237/jsoi.34.26 (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1390287827491626624 ● Search Scopus @ Elsevier (DOI): 10.11237/jsoi.34.26 (DOI: 10.11237/jsoi.34.26, CiNii: 1390287827491626624)
4.	Youji Miyamoto, 山中克之, Naoyuki Fukuda and Kazuya Akita : 再生療法の最前線 Ⅳ．サイトランスグラニュールを活用するためのポイント(Q&A), The Nippon Dental Review, Vol.79, No.9, 58-63, Aug. 2019. (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1521417755960165504 (CiNii: 1521417755960165504)
5.	Youji Miyamoto, 山中克之, Naoyuki Fukuda and Kazuya Akita : 再生療法の最前線 Ⅲ．サイトランスグラニュールを効果的に使用するために知っておきたい知識(概説), The Nippon Dental Review, Vol.79, No.9, 54-57, Aug. 2019. (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1522262179862336768 (CiNii: 1522262179862336768)
6.	Youji Miyamoto, Keiko Kudoh, Go Ohe and Natsumi Takamaru : 再生療法の最前線 Ⅴ．サイトランスグラニュールを用いた上顎洞底挙上術の長期経過, The Nippon Dental Review, Vol.79, No.9, 68-73, Aug. 2019.
7.	Kazumi Takaishi, Shigeki Fujiwara Joseph Luke, Satoru Eguchi, Ohtuka Ryo, Yuki Akazawa, Takamasa Kitamura, Kimiko Ueda Yamaguchi, Hiroshi Nakagawa, Kohichi Kani, Keiko Aota, Yukihiro Momota, Yoshiko Yamamura, Keiko Kudoh, Go Ohe, Tetsuya Tamatani, Youji Miyamoto, Masayuki Azuma, Tsutomu Iwamoto and Hiroshi Kitahata : Dental Treatment under General Anesthesia in Tokushima University Hospital - Safety Management of Disabled Patients with Special Needs during Dental Treatment-, Journal of Oral Health and Biosciences, Vol.31, No.1, 62-67, Jul. 2018. (Summary) We report about general anesthesia for disabled patients with special needs or young children during dental treatment in Tokushima University Hospital. We have administered ambulatory anesthesia or general anesthesia with short-term hospitalization for the patients. In this report, we showed anesthesia as a behavior management technique and the system for the patients who schedule ambulatory anesthesia in our hospital. We indicated the present situation of dental treatment under general anesthesia and supposed the prospects of dental care for the patients with special needs. (Keyword) 全身麻酔 / 障害者 / 日帰り全身麻酔 / 歯科治療 (Tokushima University Institutional Repository) ● Metadata: 111940 (Link to Publication Site) ● Publication site (DOI): 10.20738/johb.31.1_62 (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1390845712973457920 ● Search Scopus @ Elsevier (DOI): 10.20738/johb.31.1_62 (Tokushima University Institutional Repository: 111940, DOI: 10.20738/johb.31.1_62, CiNii: 1390845712973457920)
8.	Youji Miyamoto : 新規骨補填材としての炭酸アパタイトの開発と薬事承認, Dental Outlook, Vol.131, No.5, 877-883, May 2018.
9.	Youji Miyamoto, Tetsuya Tamatani, Go Ohe, Natsumi Takamaru, Keiko Kudoh, Yoshiko Yamamura, Kenji Fujisawa and Hirokazu Nagai : Novel Concepts of Surgery and Progress of Operative Procedure, Journal of Oral Health and Biosciences, Vol.29, No.1, 7-12, Jun. 2016. (Summary) Although the recent progress in surgery is remarkable, many dentists do not recognize it enough. From three viewpoints, we introduce and exposit new concept of treatment for wound, device (instrument) for arrest of hemorrhage, and operation procedure by surgical knife. It is always important for dentists to continue taking in new knowledge and techniques. (Keyword) 創傷処置 / 消毒 / 手術時手洗い / エナジーデバイス (Tokushima University Institutional Repository) ● Metadata: 109747 (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1050583647831063808 (Tokushima University Institutional Repository: 109747, CiNii: 1050583647831063808)
10.	Toshihiko Nagata and Youji Miyamoto : Bisphosphonate-related osteonecrosis of the jaws, Clinic All-Round, Vol.59, No.4, 540-543, Apr. 2010. (Keyword) 顎骨壊死 / ビスフォスフォネート / 副作用 / 骨粗鬆症 / 悪性腫瘍 (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1520854805754960640 (CiNii: 1520854805754960640)
11.	Kenji Fujisawa, Hirokazu Nagai and Youji Miyamoto : 自家骨を用いたサイナスリフトの術式と予後について, Shikoku Dental Research, Vol.22, No.2, 191-197, 2010. (Tokushima University Institutional Repository) ● Metadata: 109798 (Tokushima University Institutional Repository: 109798)
12.	Seiichiro Kitamura, Akira Takahashi and Youji Miyamoto : 口腔外科医に必要な局所解剖学の知識11-頸部前面の深層—口腔の炎症が全身に拡がる経路を理解するために, Dental Outlook, Vol.111, No.5, 904-911, May 2008.
13.	Seiichiro Kitamura, Akira Takahashi and Youji Miyamoto : 歯科医師・口腔外科医に必要な局所解剖学の知識11, Dental Outlook, Vol.111, No.5, 904-911, May 2008.
14.	Seiichiro Kitamura, Akira Takahashi and Youji Miyamoto : 歯科医師・口腔外科医に必要な局所解剖学の知識10—前頸部の皮下組織と顎下部—顎下部の腫れを理解するために, Dental Outlook, Vol.111, No.4, 690-697, Apr. 2008.
15.	Seiichiro Kitamura, Akira Takahashi and Youji Miyamoto : 口腔外科医に必要な局所解剖学の知識9—翼突下顎隙と翼突前隙—口腔の「奥座敷(炎症波及路)」としての重要性を考, Dental Outlook, Vol.111, No.3, 494-501, Mar. 2008.
16.	Seiichiro Kitamura, Akira Takahashi and Youji Miyamoto : 歯科医師・口腔外科医に必要な局所解剖学の知識8—咬筋・耳下腺部と側頭部，および下顎後窩—耳下腺手術および下顎骨折時の対応のために, Dental Outlook, Vol.111, No.2, 280-287, Feb. 2008.
17.	Seiichiro Kitamura, Kikuji Yamashita and Youji Miyamoto : 口腔外科医に必要な局所解剖学の知識5—舌と下顎骨—口腔機能の立役者である舌の機能を理解する, Dental Outlook, Vol.110, No.5, 868-875, Nov. 2007.
18.	Seiichiro Kitamura, 益井孝文 and Youji Miyamoto : 口腔外科医に必要な局所解剖学の知識4—舌下部—この恐い部位を克服するために, Dental Outlook, Vol.110, No.4, 652-659, Oct. 2007.
19.	Youji Miyamoto, Seiichiro Kitamura and 益井孝文 : カラーアトラス:皮膚・粘膜の下，透けて見えますか, Dental Outlook, Vol.110, No.4, 652-659, Oct. 2007.
20.	Seiichiro Kitamura, Masami Ninomiya and Youji Miyamoto : 口腔外科医に必要な局所解剖学の知識3口腔前庭—外科処置に失敗しないために, Dental Outlook, Vol.110, No.3, 458-465, Sep. 2007.
21.	Seiichiro Kitamura, Masami Ninomiya and Youji Miyamoto : 歯科医師・口腔外科医に必要な局所解剖学の知識3口腔前庭—外科処置に失敗しないために, Dental Outlook, Vol.110, No.3, 458-465, Sep. 2007.
22.	Seiichiro Kitamura, Kaori Sumida and Youji Miyamoto : 歯科医師・口腔外科医に必要な局所解剖学の知識1顔の皮下組織—``顔の美しさを守るプロ''として知っておくべきこと, Dental Outlook, Vol.110, No.1, 62-69, Jul. 2007.
23.	Daisuke Hinode, Shin-ichi Tanabe, Masaaki Yokoyama, Kenji Fujisawa, Eiji Yamauchi and Youji Miyamoto : Influence of smoking on osseointegrated implant failure: a meta-analysis, Clinical Oral Implants Research, Vol.17, No.4, 473-478, Aug. 2006. (Summary) The aim of this study was to examine the influence of smoking on osseointegrated implant failure by performing a meta-analysis. A computerized literature search using PubMed database (in English) and Japana Centra Revuo Medicina (in Japanese) was carried out to identify all relevant studies. Among 175 studies identified and chosen for detailed review, 19 were appropriate for inclusion in our meta-analysis. When smokers were compared with non-smokers, odds ratio (OR) for osseointegrated implant failure was significantly elevated (OR 2.17, 95% confidence intervals (CI), 1.67-2.83). Seven studies were appropriate to examine the influence of intra-oral location (maxillary arch vs. mandibular arch) of implant failure on smoking. The OR for implant failure occurring in the maxillary arch was significantly elevated (OR 2.06, 95% CI, 1.61-2.65), whereas the OR in the mandibular arch did not demonstrate a significant increased risk associated with smoking (OR 1.32, 95% CI, 0.72-2.4). Our meta-analysis revealed a significant relationship between smoking and the risk of osseointegrated implant failure, more particularly those implants located in the maxillary arch. (Keyword) Dental Arch / Dental Implantation, Endosseous / Dental Implants / Dental Restoration Failure / Epidemiologic Methods / Humans / Mandible / Maxilla / Smoking (Link to Publication Site) ● Publication site (DOI): 10.1111/j.1600-0501.2005.01244.x (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 16907781 ● Search Scopus @ Elsevier (PMID): 16907781 ● Search Scopus @ Elsevier (DOI): 10.1111/j.1600-0501.2005.01244.x (DOI: 10.1111/j.1600-0501.2005.01244.x, PubMed: 16907781)
24.	Seiichiro Kitamura, Chihiro Shinohara and Youji Miyamoto : 見える!わかる!臨床に役立つ解剖写真集5, Dental Outlook, Vol.107, No.5, 964-968, May 2006.
25.	Youji Miyamoto : 歯科インプラント失敗のリスクファクターと治療成績向上のための対策, Shikoku Dental Research, Vol.18, No.2, 211-220, Jan. 2006. (Tokushima University Institutional Repository) ● Metadata: 254 (Tokushima University Institutional Repository: 254)
26.	Seiichiro Kitamura, 石橋淳 and Youji Miyamoto : 臼後三角の局所解剖学, 「見える! わかる! 臨床に役立つ解剖写真集 6」，歯界展望, Vol.101, No.6, 1194-1199, 2006.
27.	面川進 and Youji Miyamoto : 歯科口腔外科領域における自己多血小板血漿ゲルの有用性, 日本アフェレシス学会誌, Vol.25, No.3, 197-203, 2006.
28.	Seiichiro Kitamura, 石橋淳 and Youji Miyamoto : 見える!わかる!臨床に役立つ解剖写真集—6, Dental Outlook, Vol.107, No.6, 1194-1199, 2006.
29.	Youji Miyamoto : 歯科インプラントの現況と課題:歯がなくなってお困りではないですか?, 秋田医学, Vol.32, No.2, 105-112, Sep. 2005.
30.	Shin-ichi Tanabe, Daisuke Hinode, Masaaki Yokoyama, Youji Miyamoto and Ryo Nakamura : 骨結合型インプラント治療の予後に対する喫煙の影響文献的考察から, Journal of Dental Health, Vol.51, No.3, 196-202, Jul. 2001.
31.	Youji Miyamoto and Masaru Nagayama : 顎・顔面の再建手術について, Shikoku Dental Research, Vol.9, No.2, 99-113, Jan. 1997.

Proceeding of International Conference:

1.	Tetsuya Yuasa, Youji Miyamoto, Yukihiro Momota, Nobuyuki Kamata, Masaru Nagayama, Masayuki Kon and Kunio Ishikawa : Effects of sintered apatite, apatite cement on differentiation of human immortalized dental papilla cells, 3rd Asian BioCeramic Symposium(ABC 2003)in conjunction with Hard-Tissue Nano-Biomaterials Symposium 2003, Fukuoka, (Summary) 1
2.	Seiko Tatehara, Youji Miyamoto, Tetsuya Yuasa, Masaaki Takechi, Masaru Nagayama, Masayuki Kon and Kunio Ishikawa : Mechanism for promotion of the differentiation of human cultured osteoblasts by calciumphosphate ceramics, 3rd Asian BioCeramic Symposium(ABC 2003)in conjunction with Hard-Tissue Nano-Biomaterials Symposium 2003, Fukuoka, (Summary) 1
3.	Youji Miyamoto, Seiko Tatehara, Tetsuya Yuasa, Hiroaki Nakanishi, Kenji Fujisawa and Masaru Nagayama : Measurement of the Zygomatic bone and pilot hole technique for safer installation of zygomatic implant, 16th International Conference on Oral and Maxillofacial Surgery(ICOMS), Athens, (Summary) 1
4.	Seiko Tatehara, Youji Miyamoto, Masaaki Takechi, Yukihiro Momota, Tetsuya Yuasa and Masaru Nagayama : Effect of locally applied basic firoblast growth factor on distraction osteogenesis in ovadectomized rats, 16th Intemational Conference on Oral and Maxillofacial Surgery(ICOMS), Athens, (Summary) 1
5.	Shiho Minamiguchi, Masaaki Takechi, Tetsuya Yuasa, Yukihiro Momota, Seiko Tatehara, Hideyuki Takano, Youji Miyamoto, Kazuhito Satomura and Masaru Nagayama : A basic research on hydroxyapatite-poly(D L-lactide-co glycolic acid)composite scaffolds for bone tissue engineering, The 5th Asian Bio Ceramics Simposium, (Summary) 1
6.	Youji Miyamoto : 新規骨補填材としての炭酸アパタイトの現状と骨再生医療への展開, 第21回再生医療学会総会，シンポジウム「新しく開発された生体材料による骨再生研究の最前線」, Mar. 2022.
7.	Naoyuki Fukuda, Takamitsu Mano, Kazuya Akita, 鎌田久美子, Takayuki Nakagawa and Youji Miyamoto : Effects Of Acidic Calcium Phosphate Concentration On Setting Reaction To ß-Tricalcium Phosphate Granular Cement, 24th Congress of the European Association for Cranio Maxillo Facial Surgery, Sep. 2018.
8.	Takamitsu Mano, Naoyuki Fukuda, Kazuya Akita, Kumiko Kamada, Naito Kurio and Youji Miyamoto : Comparative Study On Tissue Response To Low Crystalline Carbonate Apatite, NEOBONE® And Bio-Oss® In A Dog Model, 24th Congress of the European Association for Cranio Maxillo Facial Surgery, Sep. 2018.
9.	Yoshiko Yamamura, Tetsuya Tamatani, Keiko Kudoh, 秋田和也, 鎌田久美子 and Youji Miyamoto : The Changes Of Genes And MicroRNA Expression Induced By Submandibular Gland Atrophy, 24th Congress of the European Association for Cranio Maxillo Facial Surgery, Sep. 2018.
10.	Masako Fujioka-Kobayashi, Tsuru Kanji, Ishikawa Kunio and Youji Miyamoto : Fabrication and Evaluation of Carbonate Apatite-coated Calcium Carbonate Bone Substitutes, The 4th National Osteology Symposium in Switzerland, Jan. 2018.
11.	Tetsuya Tamatani, Natsumi Takamaru, Hirokazu Nagai, Kenji Fujisawa and Youji Miyamoto : Expression of SOX2 and Oct4 in human oral squamous cell carcinoma and its relationship with clinical factors, AACR Annual Meeting 2017, Apr. 2017.
12.	Tetsuya Tamatani, Natsumi Takamaru, Kenji Fujisawa, Hirokazu Nagai and Youji Miyamoto : Expression of ALDH1, Bmi-1 and CD24 in human oral squamous cell carcinoma and its relationship with clinical factors, AACR Annual Meeting 2016, Apr. 2016.
13.	Masako Fujioka-Kobayashi, Hirokazu Nagai, Kanae Hara, Kenji Fujisawa, Daisuke Uchida, Tetsuya Tamatani and Youji Miyamoto : Nobel Bone Regeneration System Using Carbonate Apatite-coated Carbonate Calcium in Vivo, American association of Oral Maxillofacial Surgeons(aaoms) 96th Annual Meeting, scientific Sessions & Exhibition, Sep. 2014.
14.	Hirokazu Nagai, Kanae Hara, Masako Fujioka-Kobayashi, Go Ohe, Tetsuya Tamatani, Kenji Fujisawa and Youji Miyamoto : Application of Low Crystalline Carbonate Apatite Combined With BMP-2 to Bone Reconstruction, American association of Oral Maxillofacial Surgeons(aaoms) 96th Annual Meeting, scientific Sessions & Exhibition, Sep. 2014.
15.	Natsumi Takamaru, Tetsuya Tamatani, Daisuke Uchida, Nobuyuki Kuribayashi, Go Ohe, Hirokazu Nagai and Youji Miyamoto : Clinicopathological Evaluation of Late cervical Lymph Node Metastatsis fo Oral Squamous Cell Carcinoma, American association of Oral Maxillofacial Surgeons(aaoms) 96th Annual Meeting, scientific Sessions & Exhibition, Sep. 2014.
16.	Tetsuya Tamatani, Natsumi Takamaru, Makoto Kinouchi, Nobuyuki Kuribayashi, Daisuke Uchida, Hirokazu Nagai and Youji Miyamoto : Express of ABCG2, ALDH1A1, CD44, and CD44 variant 9 in human oral squamous cell carcinoma and its relationship with clinical factors., AACR Annual Meeting 2014, Apr. 2014.
17.	Nobuyuki Kuribayashi, Daisuke Uchida, Makoto Kinouchi, Tetsuya Tamatani, Hirokazu Nagai and Youji Miyamoto : The role of metabotropic glutamate receptor 5 on the lymph node metastases in oral cancer., AACR Annual Meeting 2014, Apr. 2014.
18.	Makoto Kinouchi, Daisuke Uchida, Nobuyuki Kuribayashi, Tetsuya Tamatani, Hirokazu Nagai and Youji Miyamoto : Isolation of a novel metastasis-related microRNA, miR-518c-5p, induced by the stromal cell-derived factor(SDF)-1/CXCR4 system in oral cancer, AACR Annual Meeting 2014, Apr. 2014.
19.	Makoto Kinouchi, Daisuke Uchida, Nobuyuki Kuribayashi, Tetsuya Tamatani, Hirokazu Nagai and Youji Miyamoto : Functional analysis of metastasis-related microRNA induced by the stromal-cell derived factor (SDF)-1/CXCR4 system in oral cancer, American Associattion for Cancer Research Annual Meeting 2013, Apr. 2013.
20.	Nobuyuki Kuribayashi, Daisuke Uchida, Yasusei Kudo, Makoto Kinouchi, Tetsuya Tamatani, Hirokazu Nagai and Youji Miyamoto : Expression and function of CXCR4 in human salivary gland cancers, American Associattion for Cancer Research Annual Meeting 2013, Apr. 2013.
21.	Tetsuya Tamatani, Natsumi Takamaru, Makoto Kinouchi, Nobuyuki Kuribayashi, Daisuke Uchida, Hirokazu Nagai, Kenji Fujisawa and Youji Miyamoto : The expression of nuclear factor-B in human oral squamous cell carcinoma and its relationship with clinical factors, AACR Annual Meeting 2013, Apr. 2013.
22.	Daisuke Uchida, Nobuyuki Kuribayashi, Tetsuya Tamatani, Hirokazu Nagai and Youji Miyamoto : Induction of VEGF-C expression via mGluR5 in the lymph node metastases of oral cancer by the SDF-1/CXCR4 system, American Associattion for Cancer Research Annual Meeting 2012, Apr. 2012.
23.	Tetsuya Tamatani, Natsumi Takamaru, Daisuke Uchida, Hirokazu Nagai, Kenji Fujisawa and Youji Miyamoto : The expression of X-linked inhibitor of apoptosis in human oral squamous cell carcinoma and its relationship with clinical factors, American Associattion for Cancer Research Annual Meeting 2012, Apr. 2012.
24.	Daisuke Uchida, Nobuyuki Kuribayashi, Tetsuya Tamatani, Hirokazu Nagai and Youji Miyamoto : Inhibition of SDF-1/CXCR4 dependent-metastases by the treatment with metabotropic glutamate receptor 5 (mGluR5) antagonists in oral cancer, AACR 102nd Annual Meeting 2011 Proceedings, Vol.52, 583, Apr. 2011.
25.	Daisuke Uchida, Nobuyuki Kuribayashi, Tetsuya Tamatani, Hirokazu Nagai and Youji Miyamoto : Isolation and analysis of metastasis-related genes in an oral cancer cells with autocrine stromal cell-derived factor -1/CXCR4 system, Proceeding of American Association for Cancer Research, Apr. 2010.
26.	Siho Minamiguchi, Masaaki Takechi, Yukihiro Momota, Youji Miyamoto, Kazuhito Satomura and Masaru Nagayama : A research on the rat subcutaneous tissue of hydroxyapatite-polyD, L-Iactic-co-glycolic acid (PLGA)composite scaffolds for allopatry bone generation., 第1回国際シンポジウム・FDワークショップ「21 世紀の口腔科学が目指すべき方向性」, Awaji, 2007. (Summary) 1
27.	Yukihiro Momota, Youji Miyamoto, K Ishikawa, Masaaki Takechi, H Takano and Masaru Nagayama : Enhancing Effects on Aggregation of Platelets by Hydroxyapatite Putty as a Topical Hemostatic Agent for Bone, The First International Conference on Mechanics of Biomaterials and Tissues, hawaii, Dec. 2005.
28.	Kenji Fujisawa, Youji Miyamoto, Eiji Yamauchi, Masaaki Takechi, Yukihiro Momota, Tetsuya Yuasa, Seiko Tatehara and Masaru Nagayama : Immediate functional loading of Branemark system implants: One year clinical follow-up study, International Journal of Oral & Maxillofacial Surgery, Vol.34, No.supplement 1, 129, Aug. 2005.
29.	Masaaki Takechi, Yukihiro Momota, Youji Miyamoto, Kazuhito Satomura, Kenji Fujisawa and Masaru Nagayama : Effect of FGF-2 and Melatonin on the promotion of Osseogenesis around Titanium implants., First International Conference on Mechanics of Biomaterials &Tissues, 2005. (Summary) 1
30.	Yukihiro Momota, Youji Miyamoto, Ishikawa Kunio, Masaaki Takechi, Takano Hideyuki and Masaru Nagayama : Enhancing effects aggregation of platelets by hydroxyapatite putty as a topieal hemontatie agent for bone., First International Conference on Mechanics of Biomaterials&Tissues, 2005. (Summary) 1
31.	Yukihiro Momota, Youji Miyamoto, Kunio Ishikawa, Masaaki Takechi, Tetsuya Yuasa, Seiko Tatehara and Masaru Nagayama : Effects of neutral sodium hydrogen phosphate on the setting property and hemostatic ability of hydroxyapatite putty as a local hemostatic agent for bone, Journal of Biomedical Materials Research. Part B, Applied Biomaterials, Vol.69B, No.1, 99-103, Apr. 2004. (Summary) Hydroxyapatite (HAP) putty has been reported to have good hemostatic ability and excellent biocompatibility. Although the setting reaction of HAP putty and resulting transformation to HAP is the reason for this excellent biocompatibility, it also limits the handling period. In this study, the relationship between the setting reaction of HAP putty and its hemostatic ability was investigated, where neutral sodium hydrogen phosphate concentration and post-preparation time were used as indexes. A higher concentration of neutral sodium hydrogen phosphate was found to result in decreased hemostatic ability. The hemostatic ability of HAP putty decreased with time after its preparation; thus it was important to use HAP putty within 10 min after its preparation. The adhesive strength of HAP putty to bone increased with time. Therefore reliable hemostasis can be expected with HAP putty. Although the limited handling time is a drawback, HAP putty is thought to have a good potential as a hemostatic agent-it is highly reliable, and has a high hemostatic ability with excellent biocompatibility. (Keyword) hemostatic agents / hydroxyapatite putty / apatite cement / calcium- phosphate cement / setting reaction
32.	Hirakata Mayumi Luciana, Masayuki Kon, Tetsuya Yuasa, Youji Miyamoto and Kenzo Asaoka : Evaluation of apatite ceramics containing a-tricalcium phosphate in the surface layer, Journal of Dental Research, Vol.82, No.Spec B, 336, Goteborg, Jun. 2003.
33.	Youji Miyamoto, Yukihiro Momota, Masaaki Takechi, Tetsuya Yuasa, Seiko Tatehara, Masaru Nagayama and Kunio Ishikiawa : Effects of Neutral Sodium Hydrogen Phosphate on Setting Property and Hemostatic Ability of Hydroxyapatite Putty as a Local Hemostatic Agent for Bone, 15th International Symposium on Ceramics in Medicine, Vol.240-242, 373-376, Sydney, Dec. 2002. (Keyword) hydroxyapatite putty / haemostatic agent / bone wax / bome cement
34.	Kenzo Asaoka, Masayuki Kon, Kazuhito Satomura and Youji Miyamoto : Sintered porous titanium and Ti-6Al-4V alloys with calcium phosphate modification, Transactions of the Society for Biomaterials, Vol.28th Annual Meeting, 630, Tampa, Apr. 2002.
35.	Mayumi Luciana Hirakata, Masayuki Kon, Kenzo Asaoka, Youji Miyamoto and Masaaki Takechi : In vitro and in vivo reactions of compositional gradient bioceramics, Journal of Dental Research, Vol.80, No.Spec, 590, Chiba, Jun. 2001.
36.	Yukihiro Momota, Youji Miyamoto, K Ishikawa, Masaaki Takechi, Tetsuya Yuasa, T Toh, Masaru Nagayama and K Suzuki : Evalution of Hydroxyapatite-Putty as a Hemostatic Agent, Proceeding of the 13th Int.Symp.on Ceramics in Medicine, Vol.22-26, 849-852, Bologna, Nov. 2000. (Keyword) Apatite Cement / Bone Wax / Calcium Phosphate Cement / Hemostatic Agents
37.	Masaaki Takechi, Youji Miyamoto, Kunio Ishikawa, Kenzo Asaoka and Masaru Nagayama : Effects of antibiotics addition on the basic properties of nd-FSCPC, Journal of Dental Research, Vol.76, No.Spec, 242, Orlando, Mar. 1997.
38.	Youji Miyamoto, Kunio Ishikawa, Masaaki Takechi, Masayuki Kon, Kenzo Asaoka and Masaru Nagayama : Basic properties of calcium phosphate cement containing collagen, Journal of Dental Research, Vol.76, No.Spec, 243, Orlando, Mar. 1997.
39.	Masayuki Kon, Hae-Hyoung Lee, Kunio Ishikawa, Youji Miyamoto and Kenzo Asaoka : Development of calcium phosphate cement for fast-transformation to apatite, Journal of Dental Research, Vol.76, No.Spec, 421, Orlando, Mar. 1997.
40.	Kunio Ishikawa, Youji Miyamoto, Masaaki Takechi, Masayuki Kon, Kenzo Asaoka and Masaru Nagayama : Basic properties and tissue response of hydroxyapatite putty, Journal of Dental Research, Vol.76, No.Spec, 150, Orlando, Mar. 1997.
41.	Youji Miyamoto, Kunio Ishikawa, Masaaki Takechi, Masayuki Kon and Masaru Nagayama : Soft tissue responses of calcium phosphate cements, Proceedings of the 9th International Symposium on Ceramics in Medicine, 263-266, Otsu, Nov. 1996.
42.	Masaaki Takechi, Youji Miyamoto, Kunio Ishikawa, Masayuki Kon and Masaru Nagayama : Basic properties of hydroxyapatite putty made with fast-setting calcium phosphate cement and sodium alginate, Proceedings of the 9th International Symposium on Ceramics in Medicine, 235-238, Otsu, Nov. 1996.
43.	Kunio Ishikawa, Youji Miyamoto, Masaaki Takechi, Taketomo Toh, Masayuki Kon, Masaru Nagayama and Kenzo Asaoka : Approaches for bone-replacing calcium phosphate cement, --- Effect of NaHCO3 addition on the properties of calcium phosphate cement ---, Proceedings of the 9th International Symposium on Ceramics in Medicine, 255-258, Otsu, Nov. 1996.
44.	Kunio Ishikawa, Youji Miyamoto, Masayuki Kon and Kenzo Asaoka : Non-decay type fast setting calcium phosphate cement, The 2nd International Meeting of Pacific Rim Ceramic Societies, Cairns, Jul. 1996.
45.	Kunio Ishikawa, Youji Miyamoto, Masayuki Kon and Kenzo Asaoka : Behavior of non-decay-type fast- setting calcium phosphate cement, Journal of Dental Research, Vol.75, No.Spec, 21, San Francisco, Mar. 1996.
46.	H Fukao, Youji Miyamoto, M Sawada, Masaru Nagayama, Masayuki Kon, Kunio Ishikawa and Kenzo Asaoka : In vivo reactions of functionally gradient ceramic calcium phosphate, 3rd World Congress for Oral Implantology, Yokohama, Apr. 1994.

Proceeding of Domestic Conference:

1.	高井三和, Youji Miyamoto, Kenji Fujisawa, 住友孝史, 瀧雅行 and Masaru Nagayama : 右側上顎第二乳臼歯が萌出後に歯槽骨内に埋入した1例, 第50回日本口腔科学会中国四国地方部会, (Summary) 1
2.	Youji Miyamoto, Kenji Fujisawa, Seiko Tatehara, Masaaki Takechi, Yukihiro Momota, Tetsuya Yuasa, Masaru Nagayama, Eiji Yamauchi and Daisuke Hinode : ブローネマルクインプラントを使用した即時荷重インプラントの経験, 第47回日本口腔外科学会, (Summary) 1
3.	Hiroaki Nakanishi, 住友孝史, Kazuhiro Yokoyama, Kenji Fujisawa, Youji Miyamoto, Nobuyuki Kamata and Masaru Nagayama : 下顎骨骨折線上の歯に関する臨床統計学的検討, 第2回日本外傷歯学会, (Summary) 1
4.	Kenji Fujisawa, Youji Miyamoto, Tetsuya Yuasa, Yukihiro Momota, Masaaki Takechi, Seiko Tatehara, Masaru Nagayama and Eiji Yamauchi : 頬骨インプラント埋入のための頬骨の計測およびpilot hole techniqueの考案, 第32回日本口腔インプラント学会, (Summary) 1
5.	Kenji Fujisawa, 飛梅悟, Youji Miyamoto, Nobuyuki Kamata and Masaru Nagayama : 関節突起骨折患者の臨床統計的観察, 第15回日本顎関節学会総会, (Summary) 1
6.	Seiko Tatehara, Youji Miyamoto, Masaaki Takechi, Yukihiro Momota, Tetsuya Yuasa and Masaru Nagayama : 骨粗鬆症ラットの仮骨延長に関する実験的研究, 第56回日本口腔科学会総会, (Summary) 1
7.	前田恵利子, Kenji Fujisawa, Hiroaki Nakanishi, Yukihiro Momota, 日比弓紀子, Youji Miyamoto and Masaru Nagayama : 片側性下唇痩に口蓋垂裂を合供したvan der Woude症候群の1例, 第51回日本口腔科学会中国四国地方部会, (Summary) 1
8.	Eiichiro Kitaoka, Hiroaki Nakanishi, Youji Miyamoto, Nobuyuki Kamata, Yoshio Hayashi and Masaru Nagayama : 長期にわたり経過覿察を行っている先天性舌リンパ管腫の1例, 第15回日本小児口腔外学会,
9.	住友孝史, Youji Miyamoto, Kenji Fujisawa, Tetsuya Yuasa, Masaru Nagayama, Eiji Yamauchi, Fumiaki Kawano and Daisuke Hinode : インプラントの表面形状がオッセオインテグレーション獲得に及ぼす影響一滑面と粗面インプラントの比較-, 第33回日本口腔インプラント学会総会,
10.	日比弓紀子, Youji Miyamoto, Kenji Fujisawa, Yukihiro Momota, Tetsuya Yuasa, Seiko Tatehara, 住友孝史 and Masaru Nagayama : インプラント安定性評価における共鳴振動周波数分析装置(Osstell)の信頼性一ペリオテストとの比較-, 第33回日本口腔インプラント学会総会,
11.	Kenji Fujisawa, Kazuhiro Yokoyama, Youji Miyamoto, Nobuyuki Kamata and Masaru Nagayama : 薬物療法を行った顎関節症患者の臨床統計的検討, 第16回日本顎関節学会総会, (Summary) 1
12.	Youji Miyamoto, Kenji Fujisawa, Seiko Tatehara, Yukihiro Momota, Tetsuya Yuasa and Masaru Nagayama : ブローネマルクシステムを使用した即時荷重インプラントの13例, 第57回日本口腔科学会総会, (Summary) 1
13.	Tetsuya Yuasa, Youji Miyamoto, Masaaki Takechi, Yukihiro Momota, Seiko Tatehara, Masaru Nagayama and Masayuki Kon : カルシウム溶液処理による表面改質チタンが培養骨芽細胞に及ぼす影響, 第57回日本口腔科学会総会, (Summary) 1
14.	Kenji Fujisawa, Youji Miyamoto, 日比弓紀子, Masaaki Takechi, Tetsuya Yuasa, Yukihiro Momota, Seiko Tatehara and Masaru Nagayama : 水平的歯槽骨延長を行いインプラントを埋入した1例, 第34回日本口腔インプラント学会総会, (Summary) 1
15.	Tetsuya Yuasa, Youji Miyamoto, Hiroaki Nakanishi, Kenji Fujisawa, Seiko Tatehara, 瀧雅行 and Masaru Nagayama : 顔面多発骨折の変形治癒に対し顎矯正手術・骨移植術により咀嚼，審美障害の改善を認めた1例, 第6回日本口腔顎顔面外傷学会, (Summary) 1
16.	Kenji Fujisawa, Tetsuya Yuasa, Nobuyuki Kamata, Youji Miyamoto, Masaru Nagayama, Yukiko Kitase, 掘内信也 and Keiji Moriyama : 口唇口蓋裂に伴う上顎劣成長に対し，RED systemを用いて骨延長を行った2例, 第14回日本顎変形症学会総会, (Summary) 1
17.	Kenji Fujisawa, Masaaki Takechi, Eiji Yamauchi, Youji Miyamoto, Tetsuya Yuasa, Yukihiro Momota and Masaru Nagayama : 共鳴振動周波数分析装置を用いたインプラント安定性の評価1．Implant StabilityQuotient(ISQ)とインプラントの安定性に関連する因子との比較, 第35回日本口腔インプラント学会総会・学術大会, (Summary) 1
18.	Yukihiro Momota, Youji Miyamoto, 石川邦夫, 南口知穂 and Masaru Nagayama : 骨止血剤(HAP putty)による血小板凝集能の亢進, 第7回日本口腔顎顔面外傷学会総会・学術大会, (Summary) 1
19.	Akira Takahashi, Kazuya Akita, Naoyuki Fukuda, Natsumi Takamaru, Naito Kurio, Chieko Sugawara and Youji Miyamoto : Analysis of the sublingual artery using contrast-enhanced computed tomography, 日本歯科放射線学会第64回学術大会, Vol.64, 40, May 2024. (Keyword) computed tomography / dental implants / floor of the mouth / lingual perimandibular vessels / oral hemorrhage / postoperative bleeding / sublingual artery
20.	Takaharu Kudoh, Keiko Kudoh, Natsumi Takamaru, Akira Takahashi, Naito Kurio, Chisato Tonoiso, Akiko Kubo, Takashi Kawanaka, Youji Miyamoto and Hitoshi Ikushima : Unilateral Neck Volumetric-Modulated Arc Therapy, 日本歯科放射線学会第64回学術大会, May 2024.
21.	Susumu Abe, Naito Kurio, Yoritoki Tomotake, Kumiko Kamada, Toshinori Okawa, Eiji Yamauchi, Youji Miyamoto and Tetsuo Ichikawa : A case of implant-supported overdenture for severe bone defect of the mandible and vascularized fibular graft by carcinoma of the lower gingiva, 日本口腔インプラント学会誌第43回関東・甲信越支部学術大会, 105, Feb. 2024.
22.	Naoyuki Fukuda, Kazuya Akita, Natsumi Takamaru, Keiko Kudoh and Youji Miyamoto : 顎骨嚢胞摘出後に炭酸アパタイト骨補填材を充填した2例, 第27回日本顎顔面インプラント学会総会・学術大会, Dec. 2023.
23.	Kazuya Akita, Naoyuki Fukuda, Natsumi Takamaru, Keiko Kudoh and Youji Miyamoto : 操作・保持性を向上した炭酸アパタイト・コラーゲンスポンジの開発と骨再建への応用, 第27回日本顎顔面インプラント学会総会・学術大会, Dec. 2023.
24.	Naito Kurio, Kumiko Kamada, Atsushi Uesugi, 横田美保, 赤井亨輔, Yoshiko Yamamura, Akira Takahashi and Youji Miyamoto : ヒアルロン酸阻害薬による口腔扁平上皮癌細胞の老化誘導とsenolytic therapy, 第68回日本口腔外科学会総会・学術大会, Nov. 2023.
25.	Kazuya Akita, Naoyuki Fukuda, Natsumi Takamaru, Keiko Kudoh, Takaharu Kudoh, Naito Kurio and Youji Miyamoto : 炭酸アパタイト製骨補填材の炭酸基量を変えることによる吸収性と骨新生のコントロール, 第68回日本口腔外科学会総会・学術大会, Nov. 2023.
26.	福田直志, Kazuya Akita, Keiko Kudoh, 石川邦夫 and Youji Miyamoto : 顎骨欠損に使用した炭酸アパタイト人工骨の長期経過について, 第45回日本バイオマテリアル学会大会, Nov. 2023.
27.	Kazuya Akita, Naoyuki Fukuda, Natsumi Takamaru, Keiko Kudoh and Youji Miyamoto : インプラント治療を前提とした炭酸アパタイト骨補填材を用いた骨増生法の提案, 第43回日本口腔インプラント学会中国・四国支部学術大会, Oct. 2023.
28.	Naoyuki Fukuda, Kazuya Akita, Natsumi Takamaru, Keiko Kudoh and Youji Miyamoto : 顎骨嚢胞摘出後の骨欠損に使用した炭酸アパタイト骨補填材の長期経過, 第43回日本口腔インプラント学会近畿・北陸支部学術大会, Oct. 2023.
29.	Kazuya Akita, Naoyuki Fukuda, Natsumi Takamaru, Keiko Kudoh and Youji Miyamoto : 炭酸アパタイト骨補填材の歯槽骨造成術への応用, 第43回日本口腔インプラント学会近畿・北陸支部学術大会, Oct. 2023.
30.	野上幸裕, Naoyuki Fukuda, Kazuya Akita, 浦田豊彰, Natsumi Takamaru, Takaharu Kudoh, Akira Takahashi and Youji Miyamoto : 下顎のエナメル上皮腫と歯原性角化嚢胞のCTによる画像診断学的検討, 第70回NPO法人日本口腔科学会中国・四国地方部会, Oct. 2023.
31.	Naoyuki Fukuda, Kazuya Akita, Natsumi Takamaru, Keiko Kudoh and Youji Miyamoto : 炭酸アパタイトハニカムブロックによる新規骨再建・骨造成法の開発, 第53回公益社団法人日本口腔インプラント学会学術大会, Sep. 2023.
32.	Natsumi Takamaru, Naoyuki Fukuda, Naito Kurio and Youji Miyamoto : 顎矯正手術患者の術後悪心嘔吐に対するオンダンセトロンの有用性の検討, 第33回特定非営利活動法人日本顎変形症学会総会・学術大会, Jun. 2023.
33.	Kazuya Akita, Natsumi Takamaru, Naoyuki Fukuda, Hiroaki Urata and Youji Miyamoto : 術後再発をきたしたセメント芽細胞腫の1例, 第77回NPO法人日本口腔科学会学術集会, May 2023.
34.	Yoshiko Yamamura, Yasuhiro Mouri, Kumiko Kamada, Naito Kurio, Keiko Kudoh, Yasusei Kudo and Youji Miyamoto : 唾液腺の発達・再生におけるNrepの役割, 第77回NPO法人日本口腔科学会学術集会, May 2023.
35.	浦田豊彰, Natsumi Takamaru, Naoyuki Fukuda, Kazuya Akita and Youji Miyamoto : 当科におけるメトトレキサート関連リンパ増殖性疾患(MTX-LPD)の臨床的検討, 第51回口腔外科学会中国四国支部学術集会(WEB開催), Dec. 2022.
36.	Kazuya Akita, Naoyuki Fukuda, Natsumi Takamaru, Keiko Kudoh and Youji Miyamoto : 炭酸含有量が多孔質炭酸アパタイト顆粒の骨置換性に及ぼす影響, 第26回日本顎顔面インプラント学会総会, Nov. 2022.
37.	Kazuya Akita, Naoyuki Fukuda, Natsumi Takamaru, Keiko Kudoh, 石川邦夫 and Youji Miyamoto : 炭酸含有量を調整した多孔質炭酸アパタイト顆粒による骨形成と吸収能の制御, 第44回日本バイオマテリアル学会大会, Nov. 2022.
38.	Naoyuki Fukuda, Kazuya Akita, Kumiko Kamada, Natsumi Takamaru, Keiko Kudoh, Naito Kurio and Youji Miyamoto : 炭酸アパタイト製骨補填材を用いた上顎洞底挙上術後の長期予後について, 公益社団法人日本口腔インプラント学会第42回中国・四国支部学術大会, Nov. 2022.
39.	Atsushi Uesugi, Naito Kurio, Kumiko Kamada, 横田美保, Keiko Kudoh and Youji Miyamoto : 機能的スクリーニングによる新規の口腔癌関連癌抑制microRNAの検索, 第67回公益社団法人日本口腔外科学会総会・学術大会, Nov. 2022.
40.	Yoshiko Yamamura, Naito Kurio, Kumiko Kamada, Takaharu Kudoh, Akira Takahashi, Keiko Kudoh and Youji Miyamoto : チタン製インプラント体のオッセオインテグレーション獲得に関与するmiRNAの検索, 第67回日本口腔外科学会総会・学術大会, Nov. 2022.
41.	Kazuya Akita, Naoyuki Fukuda, Natsumi Takamaru, Takaharu Kudoh, Keiko Kudoh, Naito Kurio and Youji Miyamoto : 炭酸基量の異なる多孔質炭酸アパタイト顆粒の開発と骨再建, 第67回日本口腔外科学会総会・学術集会, Nov. 2022.
42.	Kumiko Kamada, Naito Kurio, Atsushi Uesugi, Yoshiko Yamamura and Youji Miyamoto : 口腔扁平上皮癌細胞株に対するヒアルロン酸合成阻害の抗腫瘍効果, 第67回公益社団法人日本口腔外科学会総会・学術大会, Nov. 2022.
43.	Naoyuki Fukuda, Natsumi Takamaru, Kazuya Akita, Keiko Kudoh, Takaaki Tsunematsu, Naozumi Ishimaru and Youji Miyamoto : 超選択的動脈塞栓術を併用して治療した上顎中心性巨細胞肉芽腫の1例, 第67回日本口腔外科学会総会・学術大会, Nov. 2022.
44.	Natsumi Takamaru, Naoyuki Fukuda, Kazuya Akita, Keiko Kudoh and Youji Miyamoto : 3次元網状連通気孔を有する炭酸アパタイトブロックの開発, 第67回日本口腔外科学会総会・学術大会, Nov. 2022.
45.	Keiko Kudoh, Naoyuki Fukuda, Kazuya Akita, Takaharu Kudoh, Natsumi Takamaru, Naito Kurio and Youji Miyamoto : ハニカム構造を有する炭酸アパタイト多孔体によるウサギ下顎骨再建への応用, 第67回日本口腔外科学会総会・学術大会, Nov. 2022.
46.	横田美保, Naito Kurio, Kumiko Kamada, Atsushi Uesugi and Youji Miyamoto : 翼突鉤切除を行ったPterygoid hamulus bursitisの1例, 第69回(公社)日本口腔科学会中国四国支部学術集会, Oct. 2022.
47.	Kazuya Akita, Naoyuki Fukuda, Natsumi Takamaru, Keiko Kudoh and Youji Miyamoto : Fabrication of carbonate apatite granules and collagen composites for new bone substitute and bone regeneration, 第52回公益社団法人日本口腔インプラント学会学術大会, Sep. 2022.
48.	Naoyuki Fukuda, Kazuya Akita, Natsumi Takamaru, Keiko Kudoh and Youji Miyamoto : 炭酸アパタイトハニカムブロックによる新規骨造成法の開発, 第52回公益社団法人日本口腔インプラント学会学術大会, Sep. 2022.
49.	Youji Miyamoto : なぜ，今，口腔がん検診か? -口腔がん・口腔粘膜疾患の診かた・見つけ方-, 日本歯科衛生学会第17回学術大会，教育講演，WEB開催, Sep. 2022.
50.	Youji Miyamoto : 歯科領域における新しいバイオセラミックスのニーズと開発 ―新規骨補填材としての炭酸アパタイトの開発と骨再生医療への応用―, 日本セラミックス協会第35回秋季シンポジウム・招待講演,特定セッションH「先進セラミックバイオマテリアル研究のフロンティア ― SDGs達成を指向した医歯工学における材料機能高度制御技術の開拓と未来展望」, Sep. 2022.
51.	TANAKA Mariko, Shinya Horiuchi, Masahiro Hiasa, Keiichiro Watanabe, Akihiko Iwasa, Natsumi Takamaru, Hirokazu Nagai, Youji Miyamoto and Eiji Tanaka : 術後に顎関節に変調をきたした顎偏位を伴う骨格性上顎前突症例, 第32回日本顎変形症学会総会・学術大会, Vol.32, No.2, 171, Jun. 2022.
52.	Youji Miyamoto : 新規骨補填材としての炭酸アパタイトの現状と顎骨再建・再生医療への展開, 第76回NPO法人日本口腔科学会学術集会，シンポジウム8「骨補填材のSDGsと未来」, Apr. 2022.
53.	Naoyuki Fukuda, Natsumi Takamaru, Kazuya Akita, Keiko Kudoh and Youji Miyamoto : 炭酸アパタイトハニカムブロックの開発と外側性骨造成への応用, 第76回NPO法人日本口腔科学会学術集会, Apr. 2022.
54.	Youji Miyamoto : 新規骨補填材としての炭酸アパタイトの現状と骨再生医療への展開, 第21回再生医療学会総会,シンポジウム13 「新しく開発された生体材料による骨再生研究の最前線」, Mar. 2022.
55.	Kazuya Akita, Naoyuki Fukuda, Natsumi Takamaru, Takaharu Kudoh, Keiko Kudoh, Naito Kurio, Akira Takahashi and Youji Miyamoto : 炭酸アパタイト顆粒(サイトランスグラニュール)の歯槽骨造成術およびソケットプリザベーションへの応用, 第50回(公社)日本口腔外科学会中国四国支部学術集会, Jan. 2022.
56.	Kumiko Kamada, Naito Kurio, Atsushi Uesugi, 横田美保, Kazuya Akita, Naoyuki Fukuda, Yoshiko Yamamura, Takaharu Kudoh, Natsumi Takamaru, Keiko Kudoh, Akira Takahashi and Youji Miyamoto : 歯性感染症により発症した側頭部ガス壊疽の1例, 第50回(公社)日本口腔外科学会中国四国支部学術集会, Jan. 2022.
57.	Kazuya Akita, Naoyuki Fukuda, MUKUMOTO Shuhei, Natsumi Takamaru, Keiko Kudoh, 都留寛治, 石川邦夫 and Youji Miyamoto : 炭酸基含有量の異なる多孔質炭酸アパタイト顆粒の開発, 第51回公益財団法人日本口腔インプラント学会学術大会, Dec. 2021.
58.	Naoyuki Fukuda, Kazuya Akita, MUKUMOTO Shuhei, Natsumi Takamaru, Keiko Kudoh and Youji Miyamoto : 炭酸アパタイト製骨補填材による広範囲骨欠損の即時再建, 第51回公益財団法人日本口腔インプラント学会学術大会, Dec. 2021.
59.	Naoyuki Fukuda, Kazuya Akita, Natsumi Takamaru, Keiko Kudoh and Youji Miyamoto : 炭酸アパタイトハニカムブロックを用いたベニアグラフトの実験的検討, 第25回公益社団法人日本顎顔面インプラント学会総会・学術大会, Dec. 2021.
60.	Youji Miyamoto : 歯科領域における新規の骨置換性バイオセラミックスのニーズと開発 -炭酸アパタイトを中心に-, 第43回日本バイオマテリアル学会大会,第8回アジアバイオマテリアル学会大会医歯薬工連携シンポジウム, Nov. 2021.
61.	Kazuya Akita, Naoyuki Fukuda, Kumiko Kamada, Atsushi Uesugi, Yoshiko Yamamura, Takaharu Kudoh, Natsumi Takamaru, Keiko Kudoh, Naito Kurio, Akira Takahashi and Youji Miyamoto : 炭酸アパタイト顆粒(サイトランスグラニュール)を用いて歯槽骨造成を行った2例, 第68 回NPO 法人日本口腔科学会中国・四国地方部会, Nov. 2021.
62.	Takaharu Kudoh, Keiko Kudoh, Hitoshi Ikushima, Akihiro Haga, Akira Takahashi and Youji Miyamoto : Dosimetric evaluation of contralateral neck in the unilateral neck volumetric modulated arc radiotherapy, 第19 回中国四国口腔癌研究会学術集会, Nov. 2021.
63.	Yoshiko Yamamura, Yasusei Kudo, Kumiko Kamada, Naito Kurio, 横田美保, Atsushi Uesugi and Youji Miyamoto : 唾液腺の発達・再生におけるΔNp63-Nrep axisの役割, 第66回日本口腔外科学会総会・学術大会, Nov. 2021.
64.	Naoyuki Fukuda, Natsumi Takamaru, Kazuya Akita, MUKUMOTO Shuhei, Keiko Kudoh and Youji Miyamoto : 嚢胞摘出後の骨欠損を炭酸アパタイト製骨補填材で即時再建した1例, 第66回日本口腔外科学会総会・学術大会, Nov. 2021.
65.	Keiko Kudoh, Naoyuki Fukuda, Kazuya Akita, Takaharu Kudoh, 椋本修平, Natsumi Takamaru, Naito Kurio, Kumiko Kamada and Youji Miyamoto : 炭酸アパタイト顆粒と魚うろこコラーゲンの複合化による新規骨補填材の開発, 第66回公益社団法人日本口腔外科学会総会・学術大会, Nov. 2021.
66.	Youji Miyamoto : 口腔領域における骨補填材としての炭酸アパタイトの現状と今後の展開, 第51回日本口腔インプラント学会，シンポジウム6 「各種造成手術における既承認骨補填材を評価する」, Oct. 2021.
67.	Youji Miyamoto : サイトランスグラニュール臨床使用3周年を迎えて, GC友の会学術講演会，東京講演会「骨再生治療の過去，現在，未来を語る -サイトランスシリーズの臨床評価と歯周組織再生治療のトレンドを知る-, Jul. 2021.
68.	Kazuya Akita, Naoyuki Fukuda, Kumiko Kamada, Go Ohe, Takamitsu Mano, 石川邦夫, 都留寛治 and Youji Miyamoto : マイクロファイバーを用いた多孔質炭酸アパタイト顆粒の開発とウサギ頭蓋骨における組織学的評価, 第75回日本口腔科学会学術集会, May 2021.
69.	Yoshiko Yamamura, Yasusei Kudo, Yasuhiro Mouri, Wenhua Shao, 横田美保 and Youji Miyamoto : 腺房細胞の再生に関わる遺伝子ネットワークの同定, 第75回日本口腔科学会学術集会, May 2021.
70.	MUKUMOTO Shuhei, Kazuya Akita, Naoyuki Fukuda, Natsumi Takamaru, Keiko Kudoh and Youji Miyamoto : 炭酸アパタイト顆粒(サイトランスグラニュール)の嚢胞摘出術への応用, 第49回(公社)日本口腔外科学会中国四国支部学術大会, Feb. 2021.
71.	Kazuya Akita, Takamitsu Mano, Naoyuki Fukuda and Youji Miyamoto : 炭酸アパタイトと豚コラーゲンの複合化による新規骨補填材の開発と骨再建への応用, 第24回日本顎顔面インプラント学会学術大会, Dec. 2020.
72.	Youji Miyamoto : 骨補填材としての炭酸アパタイトの現状と今後の展開, 第24回日本顎顔面インプラント学会学術大会, Dec. 2020.
73.	Natsumi Takamaru, Naoyuki Fukuda, Kumiko Kamada, Kazuya Akita, Go Ohe, Naito Kurio and Youji Miyamoto : 早期口腔扁平上皮癌におけるPD-L1とZEB-1の発現と予後との関連について, 第65回日本口腔外科学会総会・学術大会, Nov. 2020.
74.	Naoyuki Fukuda, Keiko Kudoh, Kazuya Akita, Takaharu Kudoh, Natsumi Takamaru, Go Ohe, Naito Kurio and Youji Miyamoto : 一方向連通気孔を有する炭酸アパタイトハニカムブロックの開発と顎骨再建への応用, 第65回日本口腔外科学会総会・学術大会, Nov. 2020.
75.	Atsushi Uesugi, 津島文彦, Youji Miyamoto and 原田浩之 : 大根おろしによる口腔アレルギー症候群の一例, 第33回日本口腔診断学会，第30回日本口腔内科学会, Oct. 2020.
76.	Youji Miyamoto : インプラント治療における口腔外科の基本手技とリスクマネージメント, 第50回日本口腔インプラント学会教育講演, Sep. 2020.
77.	Naoyuki Fukuda, Kazuya Akita, 椋本修平, Natsumi Takamaru, Keiko Kudoh and Youji Miyamoto : 新規骨補填材としてのβ型リン酸三カルシウム顆粒セメントの開発と垂直的骨造成への応用, 第50回公益社団法人日本口腔インプラント学会記念学術大会, Sep. 2020.
78.	Yoritoki Tomotake, Yuichi Ishida, Susumu Abe, Megumi Watanabe, 富永賢, Yoshizo Matsuka, Youji Miyamoto and Tetsuo Ichikawa : 徳島大学病院口腔インプラント診療部門における臨床と研究への取り組み, Journal of Japanese Society of Oral Implantology, Sep. 2020.
79.	Yoshiko Yamamura, Takamitsu Mano, Naito Kurio, Takaharu Kudoh, Keiko Kudoh, Naoyuki Fukuda and Youji Miyamoto : ピロカルピン塩酸塩を用いた口腔リンス法の有用性と安全性の検討, 第17回日本口腔ケア学会総会・学術大会, Sep. 2020.
80.	Youji Miyamoto : サイトランスグラニュール臨床使用2周年を迎えて, GC友の会学術講演会，大阪講演会「骨再生治療の過去，現在，未来を語る -骨補填材「サイトランスグラニュール」の臨床評価とその実力-」, Jul. 2020.
81.	Youji Miyamoto : 新規骨補填材としての炭酸アパタイト -その特徴，適応症と再生医療への展開-, 日本補綴歯科学会第129回学術大会シンポジウム5:最新の骨補填材について考える(Web開催), Jun. 2020.
82.	Kazuya Akita, Naoyuki Fukuda, Keiko Kudoh, Takamitsu Mano and Youji Miyamoto : マイクロファイバーをポロジェンとして用いた炭酸アパタイト多孔体の開発と骨再生医療への応用, 徳島県歯科医学大会, Feb. 2020.
83.	Youji Miyamoto : 徳島大学の現状と今後の取り組み, 第1回徳島県歯科医学大会シンポジウム「徳島県における歯科医療の現状と将来」, Feb. 2020.
84.	Keiko Kudoh, 秋田和也, Naoyuki Fukuda, Takaharu Kudoh, Naito Kurio, Go Ohe, Takamitsu Mano and Youji Miyamoto : 新規骨補填材としての炭酸アパタイトの開発と骨再生医療への応用, 徳島県歯科医学大会, Feb. 2020.
85.	Yoshitaka Suzuki, Kazuo Okura, AKIZUKI Minato, Yasutomo Yoshihara, Kazuya Akita, 聡安達, 田岡計久, Shinji Kasahara, Shuji Mori, Youji Miyamoto and Yoshizo Matsuka : ウェイクボード世界大会2018における徳島大学病院・徳島県歯科医師会の歯科医療活動とマウスガードの使用実態の調査, 徳島県歯科医学大会, Feb. 2020.
86.	Youji Miyamoto and 石川邦夫 : 歯科発日本発世界初の炭酸アパタイト人工骨の開発, 日本歯学系学会協議会第17回講演会「基礎と臨床との連携」, Vol.17, 2-21, Jan. 2020.
87.	Youji Miyamoto and 石川邦夫 : 基礎と臨床との連携 -歯科発日本発世界初の炭酸アパタイト人工骨の開発-, 日本歯学系学会協議会，第17回講演会, Jan. 2020.
88.	Naito Kurio, Kumiko Kamada, 横田美保, Yoshiko Yamamura, Aya Ushio, Yasusei Kudo, Naozumi Ishimaru and Youji Miyamoto : 上顎歯肉に発生した微小嚢胞性付属器癌の1例, 第38回日本口腔腫瘍学会総会・学術大会, Jan. 2020.
89.	Yoshiko Yamamura, Go Ohe, Yasusei Kudo, Naito Kurio, 鎌田久美子, Naoyuki Fukuda, Keiko Kudoh, Takamitsu Mano, Naozumi Ishimaru and Youji Miyamoto : 口腔扁平苔癬からの癌化が疑われた口腔扁平上皮癌の4例, 第38回日本口腔腫瘍学会総会・学術大会, Jan. 2020.
90.	Kumiko Kamada, Naito Kurio, Go Ohe, Keiko Kudoh, Yasusei Kudo, Takamitsu Mano, Naozumi Ishimaru and Youji Miyamoto : 口底に発生した類基底扁平上皮癌の1例, 第38回日本口腔腫瘍学会総会・学術大会, Jan. 2020.
91.	Naoyuki Fukuda, Keiko Kudoh, 秋田和也, Takaharu Kudoh, Go Ohe, Takamitsu Mano and Youji Miyamoto : 一方向連通気孔を有する炭酸アパタイトハニカムブロックの創製と新規GBR法の開発, 第23回日本顎顔面インプラント学会総会・学術大会, Nov. 2019.
92.	Keiko Kudoh, Kazuya Akita, Takaharu Kudoh, Naoyuki Fukuda, Takamitsu Mano, Go Ohe, 林幸壱朗, 石川邦夫 and Youji Miyamoto : 炭酸アパタイト顆粒と魚うろこコラーゲンの複合化による新規骨補填材の創製, 第41回日本バイオマテリアル学会大会, Nov. 2019.
93.	Naoyuki Fukuda, Keiko Kudoh, 秋田和也, Takaharu Kudoh, Go Ohe, Takamitsu Mano, Koichiro Hayashi, 石川邦夫 and Youji Miyamoto : 一方向連通気孔を有する炭酸アパタイトハニカムブロックの創製と下顎骨再建への応用, 第41回日本バイオマテリアル学会大会, Nov. 2019.
94.	Naoyuki Fukuda, Takamitsu Mano, Kazuya Akita, Kumiko Kamada, Yoichiro Nakajima, Keiko Kudoh, Takaharu Kudoh, Go Ohe and Youji Miyamoto : 炭酸アパタイト顆粒を用いた上顎洞底拳上術症例の検討, 日本口腔インプラント学会第39回中国・四国支部学術大会, Nov. 2019.
95.	Kazuya Akita, Naoyuki Fukuda, 鎌田久美子, Yoshiko Yamamura, Keiko Kudoh, Takaharu Kudoh, Naito Kurio, Go Ohe, Takamitsu Mano and Youji Miyamoto : ナイロンファイバーをポロゲンとして用いた炭酸アパタイト多孔体の開発と骨再建, 第64回日本口腔外科学会総会・学術大会, Oct. 2019.
96.	Kumiko Kamada, Naito Kurio, Go Ohe, Keiko Kudoh, Yoshiko Yamamura, Naoyuki Fukuda, Takamitsu Mano, Yasusei Kudo, Naozumi Ishimaru and Youji Miyamoto : 上顎歯肉に発生したMicorocystic adnexal carcinoma(MAC)の1例, 第64回日本口腔外科学会総会・学術大会, Oct. 2019.
97.	Yoshiko Yamamura, Tetsuya Tamatani, Keiko Kudoh, Naito Kurio, 鎌田久美子, Go Ohe, Takamitsu Mano and Youji Miyamoto : チタン上で培養したマウス骨芽細胞様細胞のmirVana miRNA-155-5p発現解析, 第64回日本口腔外科学会総会・学術大会, Oct. 2019.
98.	Keiko Kudoh, Naoyuki Fukuda, Kazuya Akita, Takaharu Kudoh, Go Ohe, Naito Kurio, Yoshiko Yamamura, 鎌田久美子, Takamitsu Mano and Youji Miyamoto : ハニカム構造を有する炭酸アパタイト多孔体の開発と下顎骨再建への応用, 第64回日本口腔外科学会総会・学術大会, Oct. 2019.
99.	Naito Kurio, 鎌田久美子, Go Ohe, 横田美保, Yoshiko Yamamura, Keiko Kudoh, Yasusei Kudo, Takamitsu Mano, Naozumi Ishimaru and Youji Miyamoto : 歯肉腫瘤により白血病化が明らかとなった骨髄異形成症候群の1例, 第67回日本口腔科学会中国・四国地方部会, Oct. 2019.
100.	Takaharu Kudoh, Keiko Kudoh, 鎌田久美子, Naoyuki Fukuda, Yoshiko Yamamura, Naito Kurio, Takamitsu Mano and Youji Miyamoto : Radiomicsを用いた舌癌の頸部リンパ節転移の予測, 第67回日本口腔科学会中国・四国地方部会, Oct. 2019.
101.	鎌田久美子, Naito Kurio, Go Ohe, Yoshiko Yamamura, Keiko Kudoh, Yasusei Kudo, Naozumi Ishimaru and Youji Miyamoto : 口底に発生した類基底扁平上皮癌の1例, 第18回中四国口腔癌研究会, Oct. 2019.
102.	Youji Miyamoto : 新規骨補填材としての炭酸アパタイト顆粒の臨床応用 ‐その特徴，適応症と再生医療への展開‐, 第49回日本口腔インプラント学会学術大会企画講演, Sep. 2019.
103.	Go Ohe, Kazuya Akita, 鎌田久美子, 工藤景子, 真野隆充, 石川邦夫 and Youji Miyamoto : 新規骨補填材としての炭酸アパタイト顆粒を用いた骨造成術の21例, 第49回日本口腔インプラント学会学術大会, Sep. 2019.
104.	Youji Miyamoto : 新規骨補填材としての炭酸アパタイトの実用化と再生医療への展開, 再生歯科シンポジウム岡山, May 2019.
105.	Kumiko Kamada, Naito Kurio, Keiko Kudoh, Yoshiko Yamamura, Naoyuki Fukuda, Takayuki Nakagawa, Go Ohe, Takamitsu Mano and Youji Miyamoto : 開口障害を主訴に来院した破傷風の1症例, 第48回(公社)日本口腔外科学会中国四国支部学術集会, May 2019.
106.	Keiko Kudoh, 鎌田久美子, Yoshiko Yamamura, Go Ohe, Naito Kurio, Kazuya Akita, Takaharu Kudoh, Akira Takahashi, Takamitsu Mano and Youji Miyamoto : 上顎洞内異物迷入8症例の臨床的検討, 第48回(公社)日本口腔外科学会中国四国支部学術集会, May 2019.
107.	Naito Kurio, Kumiko Kamada, Yoshiko Yamamura, Keiko Kudoh and Youji Miyamoto : 潰瘍性大腸炎の合併症と考えれらた難治性口腔潰瘍の一例, 第73回日本口腔科学会学術集会, Apr. 2019.
108.	Kazuya Akita, Naoyuki Fukuda, Kumiko Kamada, Takaharu Kudoh, Takamitsu Mano and Youji Miyamoto : マイクロファイバーを用いた多孔質炭酸アパタオトの創製と骨再建, 第73回日本口腔科学会学術集会, Apr. 2019.
109.	Yoshitaka Suzuki, Kazuo Okura, Kazuya Akita, 聡安達, Kazuhisa Taoka, Shinji Kasahara, Shuji Mori, Youji Miyamoto and Yoshizo Matsuka : ウェイクボード世界大会におけるスポーツ歯科活動, 四国歯学会第54回例会, Mar. 2019.
110.	Yoshiko Yamamura, Tetsuya Tamatani, Takamitsu Mano and Youji Miyamoto : 当科における悪性リンパ腫の臨床的検討, 第37回日本口腔腫瘍学会総会・学術大会, Jan. 2019.
111.	Naoyuki Fukuda and Youji Miyamoto : 生体不活性プラスチックに骨伝導性を付与できるか?, 第22回日本顎顔面インプラント学会総会・学術大会, Dec. 2018.
112.	Youji Miyamoto : 炭酸アパタイトの開発と骨再生医療への展開, 第22回日本顎顔面インプラント学会学術大会, Dec. 2018.
113.	Keiko Kudoh, Takaharu Kudoh, Naoyuki Fukuda, Kazuya Akita, Takamitsu Mano, Go Ohe, Takayuki Nakagawa, Kumiko Kamada and Youji Miyamoto : 魚うろこコラーゲンと炭酸アパタイト顆粒の複合化による新規骨再建材料の開発, 第22回日本顎顔面インプラント学会総会・学術大会, Dec. 2018.
114.	榊原健人, Takayuki Nakagawa, Naoyuki Fukuda, Naito Kurio, Tetsuya Tamatani, Takamitsu Mano, 大塚邦紘, Yasusei Kudo, Naozumi Ishimaru and Youji Miyamoto : 下顎骨に発生した腺性歯原性嚢胞の1例, 第66回日本口腔科学会中国・四国地方部会, Nov. 2018.
115.	Takaharu Kudoh, Keiko Kudoh, Naoyuki Fukuda, Kazuya Akita, Takamitsu Mano, Go Ohe, Takayuki Nakagawa and Youji Miyamoto : 炭酸アパタイト顆粒と魚うろこコラーゲンの複合化による新規骨再建材料の開発, 日本口腔インプラント学会第38回中国・四国支部学術大会, Nov. 2018.
116.	Go Ohe and Youji Miyamoto : 口腔扁平苔癬の癌化が疑われた口腔扁平上皮癌の2例, ジャパンオーラルヘルス学会第21回学術大会, Nov. 2018.
117.	Natsumi Takamaru, Tetsuya Tamatani, 鎌田久美子, 秋田和也, Naito Kurio, Takayuki Nakagawa, Go Ohe and Youji Miyamoto : 舌扁平上皮癌におけるPD-L1とZEB-1の発現と予後との関連について, Nov. 2018.
118.	Naoyuki Fukuda, Kazuya Akita, Takamitsu Mano and Youji Miyamoto : リン酸カルシウム溶液濃度が自己硬化型β-TCP顆粒セメントに及ぼす影響, 第63回日本口腔外科学会総会・学術大会, Nov. 2018.
119.	Yoshiko Yamamura, Tetsuya Tamatani, Keiko Kudoh, Kumiko Kamada, Takaharu Kudoh, Naito Kurio, Go Ohe, Natsumi Takamaru and Youji Miyamoto : 唾液腺の委縮により誘導される遺伝子およびマイクロRNA 発現の変化, 第63回日本口腔外科学会総会・学術大会, Nov. 2018.
120.	Youji Miyamoto : -, 日本口腔インプラント学会第38回東北・北海道支部学術大会, Oct. 2018.
121.	Kazuya Akita, Naoyuki Fukuda, 鎌田久美子, Go Ohe, Takamitsu Mano, 都留寛治, 石川邦夫 and Youji Miyamoto : マイクロファイバーを用いた多孔質炭酸アパタイト顆粒の開発と骨再建への応用, 第48回日本口腔インプラント学会学術大会, Sep. 2018.
122.	横田美保, Go Ohe, Tetsuya Tamatani, 秋田和也, 鎌田久美子, Natsumi Takamaru, Naito Kurio, 大塚邦紘, Yasusei Kudo and Youji Miyamoto : 当科におけるエナメル上皮腫の臨床統計学的検討, 第47回(公社)日本口腔外科学会中国四国支部学術集会, Jun. 2018.
123.	鎌田久美子, Naito Kurio, Keiko Kudoh, Takayuki Nakagawa, Go Ohe, 秋田和也, Naoyuki Fukuda, Natsumi Takamaru, Tetsuya Tamatani, Takamitsu Mano and Youji Miyamoto : 炭酸アパタイト顆粒(サイトランス○REAグラニュール)の上顎洞底挙上術への応用 -インプラント体同時埋入症例-, 第47回(公社)日本口腔外科学会中国四国支部学術集会, Jun. 2018.
124.	秋田和也, Naoyuki Fukuda, Go Ohe, Kenji Fujisawa, Takamitsu Mano and Youji Miyamoto : ナイロンファイバーを用いた多孔質炭酸アパタイトの開発, 第72回日本口腔科学会学術集会, May 2018.
125.	谷脇竜弥, 杉田知世, Keiji Murakami, Takashi Amoh, Atsushi Tabata, Yoshiko Yamamura, Tetsuya Tamatani, Hideaki Nagamune, Youji Miyamoto and Hideki Fujii : 幼児口腔内創部より検出された多剤耐性レンサ球菌について, 四国歯学会第52回例会, Mar. 2018.
126.	Natsumi Takamaru, Tetsuya Tamatani, Takamitsu Mano and Youji Miyamoto : 口腔扁平上皮癌におけるPD-L1発現と予後の検討, 第36回日本口腔腫瘍学会総会・学術大会, Jan. 2018.
127.	Keiko Kudoh, Takaharu Kudoh, Tetsuya Tamatani, Yoshiko Yamamura, Natsumi Takamaru, Go Ohe, Akira Takahashi, Kenji Fujisawa, 横田美保, 鎌田久美子 and Youji Miyamoto : 当科における口腔扁平苔癬症例の臨床的検討, 日本歯科人間ドック学会第20 回学術大会, Dec. 2017.
128.	鎌田久美子, Kenji Fujisawa, Keiko Kudoh, Takayuki Nakagawa, Go Ohe, Kazuya Akita, Naoyuki Fukuda, Natsumi Takamaru, Tetsuya Tamatani, Takamitsu Mano and Youji Miyamoto : 低結晶性炭酸アパタイト顆粒の上顎洞底挙上術への応用徳島大学病院におけるインプラント体同時埋入法の治験症例について, 日本顎顔面インプラント学会総会・学術大会, Dec. 2017.
129.	Kouhei Kamoi, Susumu Abe, Kenji Fujisawa, Yoritoki Tomotake, Eriko Horikawa, Eiji Yamauchi, Youji Miyamoto and Fumiaki Kawano : 着脱を容易にする機構を付与したセメント固定式上部構造を用いた1症例, 第37回公益社団法人日本口腔インプラント学会, Nov. 2017.
130.	秋田和也, Kenji Fujisawa, Naoyuki Fukuda, Go Ohe, Natsumi Takamaru, 都留寛治, 石川邦夫 and Youji Miyamoto : 低結晶性炭酸アパタイト顆粒の顎骨再建への応用 –イヌ顎骨に埋植したインプラント体周囲における組織学的検討-, 日本口腔インプラント学会第37回中国・四国支部学術大会, Nov. 2017.
131.	Naoyuki Fukuda, 秋田和也, 鎌田久美子, Natsumi Takamaru, Takayuki Nakagawa, Go Ohe, Kenji Fujisawa and Youji Miyamoto : 硬化遅延材としてのクエン酸が自己硬化型β-TCP顆粒セメントに及ぼす影響, 日本口腔インプラント学会第37回中国・四国支部学術大会, Nov. 2017.
132.	Youji Miyamoto, 鎌田久美子, Yoshiko Yamamura, Keiko Kudoh, Natsumi Takamaru, Go Ohe, Tetsuya Tamatani, Kenji Fujisawa and Takamitsu Mano : 頸部郭清術術後のリンパ漏・乳糜漏への対応, 第65回NPO法人日本口腔科学会中国・四国地方部会, Nov. 2017.
133.	鎌田久美子, Natsumi Takamaru, Keiko Kudoh, Yoshiko Yamamura, Go Ohe, Tetsuya Tamatani, Takamitsu Mano and Youji Miyamoto : 特発性血小板減少性紫斑病を有する口底癌患者の治療経験, 第65回NPO法人日本口腔科学会中国・四国地方部会, Nov. 2017.
134.	Yoshiko Yamamura, Tetsuya Tamatani, Takaharu Kudoh, 鎌田久美子, Keiko Kudoh, Natsumi Takamaru, Go Ohe, Kenji Fujisawa, Takayuki Nakagawa, Naito Kurio, Takamitsu Mano and Youji Miyamoto : 放射線治療患者におけるピロカルピン塩酸塩を用いた口腔リンス法の有用性, 第16回中国四国口腔癌研究会, Nov. 2017.
135.	Youji Miyamoto : 新規骨増生用バイオマテリアルとしての炭酸アパタイトの開発と薬事承認, 第62回日本口腔外科学会学術大会, Oct. 2017.
136.	Takayuki Nakagawa, 太田耕司, 武知正晃 and Youji Miyamoto : 破骨細胞前駆細胞の分化におけるゾレドロン酸の標的遺伝子の網羅的探索, 第62回日本口腔外科学会学術大会, Oct. 2017.
137.	Natsumi Takamaru, Hirokazu Nagai, Kazuya Akita, Yasusei Kudo, Naozumi Ishimaru and Youji Miyamoto : 翼突下顎隙に生じた紡錐細胞脂肪腫の1例, 第62回日本口腔外科学会学術大会, Oct. 2017.
138.	秋田和也, Naoyuki Fukuda, Go Ohe, Kenji Fujisawa and Youji Miyamoto : 炭酸アパタイト・コラーゲン複合体を用いた骨再建に関する基礎的研究, 第62回日本口腔外科学会学術大会, Oct. 2017.
139.	Yoshiko Yamamura, Tetsuya Tamatani, Keiko Kudoh, Naoyuki Fukuda, Takayuki Nakagawa, Natsumi Takamaru, Go Ohe, Kenji Fujisawa and Youji Miyamoto : チタン上で培養したマウス骨芽細胞様細胞の硬組織分化にグルコース濃度が及ぼす影響, 第62回日本口腔外科学会学術大会, Oct. 2017.
140.	Naoyuki Fukuda, 秋田和也, 森悦秀 and Youji Miyamoto : 新規骨補填再建材としての自己硬化型β-TCP顆粒セメントの開発, 第62回日本口腔外科学会学術大会, Oct. 2017.
141.	Go Ohe, Natsumi Takamaru, Takayuki Nakagawa, Tetsuya Tamatani, Kazuya Akita and Youji Miyamoto : 免疫チェックポイント阻害剤抗PD-L1抗体とOK-432の併用による口腔癌に対する抗腫瘍効果, 第62回日本口腔外科学会学術大会, Oct. 2017.
142.	Youji Miyamoto : 骨補填材としての炭酸アパタイトの開発と薬事承認に向けて, 第47回日本口腔インプラント学会学術大会, Sep. 2017.
143.	秋田和也, Naoyuki Fukuda, Go Ohe, Kenji Fujisawa, Youji Miyamoto, 都留寛治 and 石川邦夫 : 新規骨再生材料としての炭酸アパタイト・コラーゲン複合体の開発, 第47回日本口腔インプラント学会学術大会, Sep. 2017.
144.	Kenji Fujisawa, 秋田和也, Naoyuki Fukuda, Go Ohe, Natsumi Takamaru, 都留寛治, 石川邦夫 and Youji Miyamoto : 低結晶性炭酸アパタイト顆粒の骨再生への応用 –ウサギ大腿骨内における組織学的検討‐, 第47回日本口腔インプラント学会学術大会, Sep. 2017.
145.	横田美保, Keiko Kudoh, Tetsuya Tamatani, 鎌田久美子, Naoyuki Fukuda, Natsumi Takamaru, Yoshiko Yamamura, Takayuki Nakagawa, Go Ohe, Takaharu Kudoh, Akira Takahashi, Kenji Fujisawa, 鯨岡聡子, Yasusei Kudo, Naozumi Ishimaru and Youji Miyamoto : 当科における歯原性角化嚢胞の臨床的検討, 第46回日本口腔外科学会中国四国学術集会, May 2017.
146.	Kazuya Akita, Natsumi Takamaru, Tetsuya Tamatani, 鎌田久美子, Yoshiko Yamamura, Keiko Kudoh, Go Ohe, Kenji Fujisawa and Youji Miyamoto : 当科における手術拒否口腔癌症例の臨床的検討, 第46回日本口腔外科学会中国四国学術集会, May 2017.
147.	Akira Takahashi, Takaharu Kudoh, Keiko Kudoh, Natsumi Takamaru, Go Ohe, Tetsuya Tamatani, Kenji Fujisawa, Chieko Sugawara and Youji Miyamoto : 咽頭扁桃結石に関するX線診断学的検討, 第71回NPO法人日本口腔科学会学術集会, Apr. 2017.
148.	Tetsuya Tamatani, Natsumi Takamaru, Go Ohe, Akira Takahashi, Kenji Fujisawa and Youji Miyamoto : 早期口腔扁平上皮癌患者におけるABCG2，ALDH1，Bmi-1，CD24およびCD44発見に関する検討, 第71回NPO法人日本口腔科学会学術集会, Apr. 2017.
149.	Yoshiko Yamamura, Kenji Fujisawa, Takaharu Kudoh, Keiko Kudoh, 秋田和也, 中村勇貴, Natsumi Takamaru, Go Ohe, Tetsuya Tamatani and Youji Miyamoto : ピロカルピン塩酸塩(サラジェン)を用いた口腔リンス法の有効性と安全性の検討, 第14回日本口腔ケア学会総会・学術大会, Apr. 2017.
150.	Natsumi Takamaru, Tetsuya Tamatani, Hirokazu Nagai and Youji Miyamoto : 早期口腔扁平上皮癌患者におけるCD20の発現に関する検討, 第35回日本口腔腫瘍学会総会・学術大会, Jan. 2017.
151.	Keiko Kudoh, 鎌田久美子, 横田美保, Natsumi Takamaru, Yoshiko Yamamura, Go Ohe, Takaharu Kudoh, Akira Takahashi, Tetsuya Tamatani, Kenji Fujisawa, Hirokazu Nagai and Youji Miyamoto : 当科における口腔がん検診の現況, 日本歯科人間ドック学会第19回学術大会, Dec. 2016.
152.	Go Ohe, Kenji Fujisawa, Hirokazu Nagai and Youji Miyamoto : 低結晶性炭酸アパタイトを用いた骨再建に関する基礎的研究, 第20回公益社団法人日本顎顔面インプラント学会総会・学術大会, Dec. 2016.
153.	仙頭慎哉, 北村直也, 山本哲也, 浜川裕之, 佐々木朗, Youji Miyamoto, 両家和男 and 上山吉哉 : 口腔癌に対する化学療法におけるパロノセトロンの悪心・嘔吐予防効果, 第61回(公社)日本口腔外科学会総会・学術大会, Nov. 2016.
154.	山之内浩司, Keiko Kudoh, 小暮大地 and Youji Miyamoto : 過去10年間における抗血栓療法下でのインプラント治療に対する臨床的検討, 第61回(公社)日本口腔外科学会総会・学術大会, Nov. 2016.
155.	Yoshiko Yamamura, Tetsuya Tamatani, Go Ohe, Kenji Fujisawa, Natsumi Takamaru, Keiko Kudoh, Hirokazu Nagai and Youji Miyamoto : チタン上で培養したヒト骨髄間葉系幹細胞の遺伝子およびmicroRNA発現の解析, 第61回(公社)日本口腔外科学会総会・学術大会, Nov. 2016.
156.	Natsumi Takamaru, 鎌田久美子, Keiko Kudoh, Tetsuya Tamatani, Yoshiko Yamamura, Go Ohe, Hirokazu Nagai and Youji Miyamoto : 口腔内に発生したメトトレキサート関連リンパ増殖性疾患の2例, 第61回(公社)日本口腔外科学会総会・学術大会, Nov. 2016.
157.	Yoshiko Yamamura, Tetsuya Tamatani, Go Ohe, Kenji Fujisawa, Natsumi Takamaru, Keiko Kudoh, Hirokazu Nagai and Youji Miyamoto : チタンが培養ヒト骨髄間葉系幹細胞に及ぼす影響 –マイクロアレイによる解析-, 日本バイオマテリアル学会シンポジウム2016, Nov. 2016.
158.	Horikawa Eriko, Susumu Abe, Kenji Fujisawa, Akira Takahashi, Eiji Yamauchi, Yoritoki Tomotake, Youji Miyamoto and Fumiaki Kawano : 単独歯インプラントの隣在歯の生存率に関する調査, 日本口腔インプラント学会中国・四国支部学術大会, 45, Nov. 2016.
159.	Kamata Kumiko, Akira Takahashi, Go Ohe, Natsumi Takamaru, Kenji Fujisawa, Hirokazu Nagai, Susumu Abe and Youji Miyamoto : CT画像による副オトガイ孔の発現頻度に関する検討, 日本口腔インプラント学会中国・四国歯部学術大会, 33, Nov. 2016.
160.	Tetsuya Tamatani, Natsumi Takamaru, 鎌田久美子, 横田美保, Yoshiko Yamamura, Keiko Kudoh, Go Ohe, Takaharu Kudoh, Akira Takahashi, Kenji Fujisawa, Hirokazu Nagai and Youji Miyamoto : 当科における早期口腔扁平上皮癌患者の臨床的検討, 第64回NPO法人日本口腔科学会中国・四国地方部会, Oct. 2016.
161.	横田美保, Kenji Fujisawa, Yoshiko Yamamura, Tetsuya Tamatani, Natsumi Takamaru, Keiko Kudoh, Go Ohe, Hirokazu Nagai, 鯨岡聡子, Naozumi Ishimaru and Youji Miyamoto : 骨破壊を伴った顎放線菌症の2例, 第64回NPO法人日本口腔科学会中国・四国地方部会, Oct. 2016.
162.	Akira Takahashi, 鎌田久美子, Yoshiko Yamamura, Natsumi Takamaru, Takaharu Kudoh, Keiko Kudoh, Go Ohe, Kenji Fujisawa, Tetsuya Tamatani, Hirokazu Nagai and Youji Miyamoto : 口腔扁平上皮癌の頸部リンパ節転移診断におけるFDG-PET検査の有用性, 第15回中国四国口腔癌研究会, Oct. 2016.
163.	Tetsuya Tamatani, Natsumi Takamaru, Hirokazu Nagai and Youji Miyamoto : 口腔扁平上皮癌におけるSOX2発現の臨床病理学的意義, 第75回日本癌学会学術大会総会, Oct. 2016.
164.	Kenji Fujisawa, Hirokazu Nagai, Natsumi Takamaru, 都留寛治, 石川邦夫 and Youji Miyamoto : 低結晶性炭酸アパタイトのインプラント領域への応用 –イヌ顎骨への印プラント体との同時埋植-, 第46回公益社団法人日本口腔インプラント学会学術大会, Sep. 2016.
165.	Go Ohe, Masako Fujioka-Kobayashi, Kenji Fujisawa, Hirokazu Nagai and Youji Miyamoto : 炭酸アパタイト被膜炭酸カルシウムを用いた新規骨置換材料による骨再生の試み, 第46回公益社団法人日本口腔インプラント学会学術大会, Sep. 2016.
166.	Takaharu Kudoh, Keiko Kudoh, Akira Takahashi and Youji Miyamoto : 口腔癌に対する強度変調放射線治療の有効性について, NPO法人日本歯科放射線学会第57回学術大会・第13回定例総会, Jun. 2016.
167.	Kumiko Kamada, Keiko Kudoh, Tetsuya Tamatani, Natsumi Takamaru, Yoshiko Yamamura, Go Ohe, Kenji Fujisawa, Hirokazu Nagai and Youji Miyamoto : 舌に発生したメトトレキサート関連リンパ増殖性疾患の1例, 第45回(公社)日本口腔外科学会中国四国支部学術大会, May 2016.
168.	Go Ohe, Kumiko Kamada, Natsumi Takamaru, Tetsuya Tamatani, Kenji Fujisawa, Hirokazu Nagai and Youji Miyamoto : 頬粘膜に発生した基底細胞腺腫の1例, 第45回(公社)日本口腔外科学会中国四国支部学術大会, May 2016.
169.	Akira Takahashi, Takaharu Kudoh, Keiko Kudoh, Natsumi Takamaru, Go Ohe, Tetsuya Tamatani, Hirokazu Nagai, Kenji Fujisawa and Youji Miyamoto : 硬口蓋を基準とした後上歯槽動脈の走行に関する検討, 第70回NPO法人日本口腔科学会学術集会, Apr. 2016.
170.	Takaharu Kudoh, Tetsuya Tamatani, Kenji Fujisawa, Keiko Kudoh, Natsumi Takamaru, Hirokazu Nagai and Youji Miyamoto : 口腔癌に対する強度変調放射線治療に関する臨床的検討, 第34回日本口腔腫瘍学会総会・学術大会, Jan. 2016.
171.	Chieko Sugawara, Akira Takahashi, Takaharu Kudoh, Fumiaki Kawano and Youji Miyamoto : 歯科受診を契機にして発見された他科領域の悪性疾患症例, 日本歯科放射線学会第35回関西・九州合同地方会, Dec. 2015.
172.	Yoshiko Yamamura, Kenji Fujisawa and Youji Miyamoto : 口腔がん患者の歯科疾患罹患状況, 第18回日本歯科人間ドック学会・学術大会, Dec. 2015.
173.	Go Ohe, 鎌田久美子, Kenji Fujisawa, Hirokazu Nagai and Youji Miyamoto : 低結晶性炭酸アパタイトを用いた骨再生療法に関する基礎的研究, 第19回日本顎顔面インプラント学会学術大会, Nov. 2015.
174.	Kenji Fujisawa, Hirokazu Nagai, Natsumi Takamaru, Go Ohe, 都留寛治, 石川邦夫 and Youji Miyamoto : ゼラチン複合型炭酸アパタイトフォームの物理学的評価, 第37回日本バイオマテリアル学会大会, Nov. 2015.
175.	Akira Takahashi, Chieko Sugawara, Takaharu Kudoh, Keiko Kudoh, Natsumi Takamaru, Go Ohe, Tetsuya Tamatani, Kenji Fujisawa, Hirokazu Nagai and Youji Miyamoto : 舌扁桃結石に関するX線診断学的検討, 第63回NPO法人日本口腔科学会中国・四国地方部会, Nov. 2015.
176.	Kenji Fujisawa, Go Ohe, Natsumi Takamaru, Tetsuya Tamatani, Yoshiko Yamamura, Keiko Kudoh, Hirokazu Nagai and Youji Miyamoto : 上顎洞底挙上術を併用したインプラントの予後に関する臨床的検討, 第63回NPO法人日本口腔科学会中国・四国地方部会, Nov. 2015.
177.	Tetsuya Tamatani, Natsumi Takamaru, Go Ohe, Hirokazu Nagai and Youji Miyamoto : 口腔扁平上皮癌におけるCD44,ABCG2およびALDH1の発現に関する検討, 第60回公益社団法人日本口腔外科学会総会・学術大会, Oct. 2015.
178.	Hirokazu Nagai, Kenji Fujisawa, Go Ohe, Masako Fujioka-Kobayashi, Natsumi Takamaru, Takaharu Kudoh, Tetsuya Tamatani and Youji Miyamoto : 低結晶性炭酸アパタイトの骨再建への応用第1報イヌ歯槽骨欠損部への移植, 第60回公益社団法人日本口腔外科学会総会・学術大会, Oct. 2015.
179.	Natsumi Takamaru, Go Ohe, Tetsuya Tamatani, Hirokazu Nagai and Youji Miyamoto : 静脈性血管奇形に対するNd:YAGレーザーを用いた光凝固療法, 第60回公益社団法人日本口腔外科学会総会・学術大会, Oct. 2015.
180.	Tetsuya Tamatani, Natsumi Takamaru, Go Ohe, Hirokazu Nagai and Youji Miyamoto : 口腔癌におけるBmi-1とCD24発現の臨床病理病理学的意義, 第74回日本癌学会学術総会, Oct. 2015.
181.	Hirokazu Nagai, Kenji Fujisawa, 都留寛治, 石川邦夫 and Youji Miyamoto : 低結晶性炭酸アパタイトの骨再建への応用イヌ顎骨に作製した骨欠損部への移植, 第45回公益社団法人日本口腔インプラント学会学術大会, Sep. 2015.
182.	Youji Miyamoto : 外科の新しい概念および手術手技, 四国歯学会第47回例会, Jun. 2015.
183.	Akira Takahashi, Chieko Sugawara, Takaharu Kudoh, Keiko Kudoh, Natsumi Takamaru, Go Ohe, Tetsuya Tamatani, Hirokazu Nagai and Youji Miyamoto : 口蓋扁桃結石に関するX線診断学的検討 -パノラマX線写真における描出状況, 第69回日本口腔科学会学術集会, May 2015.
184.	鎌田久美子, Nobuyuki Kuribayashi, Natsumi Takamaru, Go Ohe, Tetsuya Tamatani, Hirokazu Nagai, Kenji Fujisawa and Youji Miyamoto : 超選択的動注化学療法が奏功した頸部リンパ節転移を伴った下顎歯肉癌の1例, 第44回(公社)日本口腔外科学会中国四国支部学術集会, Apr. 2015.
185.	Masako Fujioka-Kobayashi, Nobuyuki Kuribayashi, Tetsuya Tamatani, Hirokazu Nagai and Youji Miyamoto : 下顎に発生したエナメル上皮線維象牙質腫の一例, 第33回日本口腔腫瘍学会学術大会, Jan. 2015.
186.	鎌田久美子, Go Ohe, Kenji Fujisawa, Hirokazu Nagai and Youji Miyamoto : インプラントの経過不良により来科したビスフォスフォネート製剤投与患者の臨床的検討, 公益社団法人日本口腔外科学会・学術大会第34回中国・四国支部学術大会, Nov. 2014.
187.	Youji Miyamoto : インプラント治療の良い点，悪い点, 公益社団法人日本口腔外科学会・学術大会第34回中国・四国支部学術大会, Nov. 2014.
188.	Masako Fujioka-Kobayashi, Hirokazu Nagai, Kenji Fujisawa, 都留寛治, 石川邦夫, 山中克之, 熊谷知宏 and Youji Miyamoto : 炭酸アパタイト被覆炭酸カルシウムを用いたハイブリッド型骨補填材料による骨再生の試み, 第36回日本バイオマテリアル学会大会, Nov. 2014.
189.	Keiko Kudoh, Tetsuya Tamatani, Natsumi Takamaru, 木内誠, Kumiko Kamada, Hirokazu Nagai, Kazumi Takaishi and Youji Miyamoto : 水酸化カルシウム系根管充填材料の根尖外溢出により下歯槽神経麻痺が生じた1例, 第62回NPO法人日本口腔科学会中国・四国地方部会, Oct. 2014.
190.	Takaharu Kudoh, Nobuyuki Kuribayashi, Keiko Kudoh, Go Ohe, Masako Fujioka-Kobayashi, Tetsuya Tamatani, Hirokazu Nagai, 近藤智之, Naozumi Ishimaru and Youji Miyamoto : 舌に発生した孤立性神経線維腫の1例, 第62回NPO法人日本口腔科学会中国・四国地方部会, Oct. 2014.
191.	Keiko Kudoh, Tetsuya Tamatani, Natsumi Takamaru, 木内誠, 鎌田久美子, Hirokazu Nagai, Kazumi Takaishi and Youji Miyamoto : 水酸化カルシウム系根管充填材料の根尖外溢出により下歯槽神経麻痺が生じた1例, 第62回NPO法人日本口腔科学会中国・四国地方部会, Oct. 2014.
192.	Masako Fujioka-Kobayashi, Hirokazu Nagai, 原香苗, Kumiko Kamada, Takaharu Kudoh, Kenji Fujisawa and Youji Miyamoto : 炭酸アパタイト被膜炭酸カルシウムを用いた新規骨置換材料による骨再生の試み, 第59回(公社)日本口腔外科学会総会・学術大会, Oct. 2014.
193.	Masako Fujioka-Kobayashi, Hirokazu Nagai, 原香苗, 鎌田久美子, Takaharu Kudoh, Kenji Fujisawa and Youji Miyamoto : 炭酸アパタイト被膜炭酸カルシウムを用いた新規骨置換材料による骨再生の試み, 第59回(公社)日本口腔外科学会総会・学術大会, Oct. 2014.
194.	Chieko Sugawara, Akira Takahashi, Fumiaki Kawano and Youji Miyamoto : 歯科領域における超音波検査の現状, 日本超音波医学会第24回四国地方会学術集会, Oct. 2014. (Keyword) 口腔悪性腫瘍 / 頸部リンパ節転移
195.	Tetsuya Tamatani, Natsumi Takamaru, 木内誠, Nobuyuki Kuribayashi, Daisuke Uchida, Hirokazu Nagai and Youji Miyamoto : 口腔癌におけるABCG2とALDH1A1発現の臨床病理学的意義, 第73回日本癌学会学術総会, Sep. 2014.
196.	木内誠, Daisuke Uchida, Nobuyuki Kuribayashi, Tetsuya Tamatani, Hirokazu Nagai and Youji Miyamoto : miR-518c-5pの口腔癌におけるmetastamiRとしての可能性, 第6回日本RNAi研究会, Aug. 2014.
197.	Kenji Fujisawa, Youji Miyamoto, Aimi Yamamoto, 明人和田, Koji Hayakumo, 安田勝裕, 齋賀洋二, 福井一裕, 齋賀明彦, Jun Kusaka, 槇大, 川島周, 神山有史, 笠井祥資, Akiko Ishigami and Akiyoshi Nishimura : 徳島県における合同遺体対応訓練-歯科医師と他職種の連携について-．, 第13回警察歯科医会全国大会, 95, Aug. 2014.
198.	Kumiko Kamada, Go Ohe, Takaharu Kudoh, Hirokazu Nagai and Youji Miyamoto : 舌根部に発生した骨性分離腫の1例, 第68回NPO法人日本口腔科学会学術集会, May 2014.
199.	木内誠, Daisuke Uchida, Nobuyuki Kuribayashi, Tetsuya Tamatani, Hirokazu Nagai and Youji Miyamoto : CXCR4システムにより誘導されるmiR-518c-5pの口腔癌における転移関連microRNAとしての可能性, 第68回NPO法人日本口腔科学会学術集会, May 2014.
200.	Akira Takahashi, Nobuyuki Kuribayashi, Takaharu Kudoh, Daisuke Uchida, Tetsuya Tamatani, Hirokazu Nagai and Youji Miyamoto : 口腔癌の頸部リンパ節マッピングによる頸部リンパ節転移診断精度の検討, 日本口腔外科学会中国四国支部学術大会徳島, Apr. 2014.
201.	Masako Fujioka-Kobayashi, Nobuyuki Kuribayashi, Daisuke Uchida, Tetsuya Tamatani, Hirokazu Nagai and Youji Miyamoto : 口腔領域にみられた転移性癌の臨床的検討, 32回日本口腔腫瘍学会学術集会, Jan. 2014.
202.	Kumiko Kamada, Go Ohe, Kenji Fujisawa, Daisuke Uchida and Youji Miyamoto : 吸収性メッシュと骨髄海綿骨細片骨移植で再建した上顎前歯部にインプラント治療を行った1例, 第17回日本顎顔面インプラント学会学術大会, Nov. 2013.
203.	鎌田久美子, Go Ohe, Kenji Fujisawa, Daisuke Uchida and Youji Miyamoto : 吸収性メッシュと骨髄海綿骨細片骨移植で再建した上顎前歯部にインプラント治療を行った1例, 第17回日本顎顔面インプラント学会学術大会, Nov. 2013.
204.	Hirokazu Nagai, 原香苗, Masako Fujioka-Kobayashi, Kenji Fujisawa, 都留寛治, 山本克史, 石川邦夫 and Youji Miyamoto : 低結晶性炭酸アパタイトの顎骨再建への応用に関する基礎的研究第6報 BMP-2との併用効果, 第35回日本バイオマテリアル学会大会, Nov. 2013.
205.	Masako Fujioka-Kobayashi, Kenji Fujisawa, Go Ohe, Kazuo Okura, Susumu Abe, Daisuke Uchida, Hirokazu Nagai and Youji Miyamoto : 当科における過去 20 年間のインプラント脱落症例の検討―early failure と late failure の比較―, 第33回口腔インプラント学会中国・四国支部学術集会, Nov. 2013.
206.	Susumu Abe, Kenji Fujisawa, Takeshi Yamamoto, Fumiaki Kawano and Youji Miyamoto : A case of immediate loading implant placemet with maxillary sinus floor elevation, 公益社団法人日本口腔インプラント学会第33回中国四国支部総会学術大会, Nov. 2013.
207.	Masako Fujioka-Kobayashi, Kenji Fujisawa, Go Ohe, Susumu Abe, Kazuo Okura, Daisuke Uchida, Hirokazu Nagai and Youji Miyamoto : 当科における過去 20 年間のインプラント脱落症例の検討―early failure と late failure の比較―, 第33回口腔インプラント学会中国・四国支部学術集会, Nov. 2013.
208.	Kenji Fujisawa, Takaharu Kudoh, Masako Fujioka-Kobayashi, Keiko Kudoh, Tetsuya Tamatani, Hirokazu Nagai and Youji Miyamoto : 下顎枝垂直骨切り術後の下顎頭位変化の検討, 第61回NPO法人日本口腔科学会中国・四国地方部会, Nov. 2013.
209.	Takaharu Kudoh, Kenji Fujisawa, Keiko Kudoh, Masako Fujioka-Kobayashi, Nobuyuki Kuribayashi, Natsumi Takamaru, Go Ohe, Daisuke Uchida, Akira Takahashi, Tetsuya Tamatani, Hirokazu Nagai, Hitoshi Ikushima and Youji Miyamoto : 当科における強度変調放射線治療(IMRT)の経験, 第12回中国四国口腔癌研究会学術講演会, Nov. 2013.
210.	Tetsuya Tamatani, Natsumi Takamaru, Masako Fujioka-Kobayashi, Nobuyuki Kuribayashi, Go Ohe, Daisuke Uchida, Kenji Fujisawa, Hirokazu Nagai and Youji Miyamoto : 当科を受診した悪性リンパ腫の臨床的検討, 第58回(公社)日本口腔外科学会総会・学術大会, Oct. 2013.
211.	Natsumi Takamaru, 鎌田久美子, Hirokazu Nagai and Youji Miyamoto : 舌から喉頭蓋前間隙へ移動した迷入魚骨の1例, 第58回(公社)日本口腔外科学会総会・学術大会, Oct. 2013.
212.	Masako Fujioka-Kobayashi, Keiko Kudoh, Nobuyuki Kuribayashi, Hirokazu Nagai and Youji Miyamoto : 顎関節に生じた頭蓋底まで及んだ偽痛風の1例, 第58回(公社)日本口腔外科学会総会・学術大会, Oct. 2013.
213.	Nobuyuki Kuribayashi, Daisuke Uchida, 木内誠, Tetsuya Tamatani, Hirokazu Nagai and Youji Miyamoto : CXCR4システムを介した口腔癌のリンパ節転移におけるmGluR5のリンパ管新生への関与, 第58回(公社)日本口腔外科学会総会・学術大会, Oct. 2013.
214.	Tetsuya Tamatani, Natsumi Takamaru, 木内誠, Nobuyuki Kuribayashi, Daisuke Uchida, Hirokazu Nagai and Youji Miyamoto : The clinicopathological role of the nuclear expression of nuclear factor-B in human oral squamous cell carcinoma, 第72回日本癌学会学術大会総会, Oct. 2013.
215.	Nobuyuki Kuribayashi, Daisuke Uchida, 木内誠, Tetsuya Tamatani, Hirokazu Nagai and Youji Miyamoto : Mechanism of transcriptional regulation in metabotropic glutamate receptor-5 induced by the CXCR4 signaling pathway, 第72回日本癌学会学術大会総会, Oct. 2013.
216.	木内誠, Daisuke Uchida, Nobuyuki Kuribayashi, Tetsuya Tamatani, Hirokazu Nagai and Youji Miyamoto : Isolation of a novel metastasis-related microRNA induced by the CXCR4 system in oral cancer, 第72回日本癌学会学術大会総会, Oct. 2013.
217.	鎌田久美子, Kenji Fujisawa, Go Ohe, Hirokazu Nagai and Youji Miyamoto : オッセオインテグレーション獲得前のインプラント脱落症例の検討-最近10年間とそれ以前の症例との比較-, 第43回公益社団法人日本口腔インプラント学会学術大会, Sep. 2013.
218.	木内誠, Daisuke Uchida, Nobuyuki Kuribayashi, Tetsuya Tamatani, Hirokazu Nagai and Youji Miyamoto : stromal-cell derived factor (SDF)-1/CXCR4システムにより誘導される口腔癌の転移関連マイクロRNAの検索, 第5回日本RNAi研究会, Aug. 2013.
219.	Masako Fujioka-Kobayashi, Nobuyuki Kuribayashi, Natsumi Takamaru, Keiko Kudoh, Go Ohe, Daisuke Uchida, Tetsuya Tamatani, Kenji Fujisawa, Hirokazu Nagai and Youji Miyamoto : 当科における過去8年間の下顎関節突起骨折の臨床的検討, 第15回口腔顎顔面外傷学会学術大会, Jul. 2013.
220.	Shinya Horiuchi, Akihiro Yasue, Nobuhiko Kawai, Shingo Kuroda, Youji Miyamoto and Eiji Tanaka : 先端巨大症に起因した骨格性下顎前突症に対し舌縮小術を併用して外科的矯正治療を行った1例, 第23回日本顎変形症学会大会, Jun. 2013.
221.	Natsumi Takamaru, Hirokazu Nagai, Go Ohe, Daisuke Uchida, Tetsuya Tamatani, Kenji Fujisawa and Youji Miyamoto : 当科におけるビスフォスフォネート関連顎骨壊死(BRONJ)患者の臨床的検討, 第67回NPO法人日本口腔科学会学術集会, Jun. 2013.
222.	Makoto Kinouchi, Daisuke Uchida, Nobuyuki Kuribayashi, Tetsuya Tamatani, Hirokazu Nagai and Youji Miyamoto : Stromal-cell derived factor(SDF)-1/CXCR4システムにより誘導される口腔癌の転移関連マイクロRNAの検索, 第37回日本頭頸部癌学会, Jun. 2013.
223.	Akira Takahashi, Takaharu Kudoh, Chieko Sugawara and Youji Miyamoto : 口蓋扁桃石灰化に関するX線診断学的検討 -CTにおける描出状況-, 第54回NPO法人日本歯科放射線学会学術大会, Jun. 2013.
224.	Natsumi Takamaru, Hirokazu Nagai, Go Ohe, Daisuke Uchida, Tetsuya Tamatani, Kenji Fujisawa and Youji Miyamoto : 当科におけるビスフォスフォネート関連顎骨壊死(BRONJ)患者の臨床的検討, 第67回NPO法人日本口腔科学会学術集会, May 2013.
225.	Masako Fujioka-Kobayashi, Youji Miyamoto and 井関祥子 : BMP2の骨誘導に対するFGFファミリーの併用効果, 第67回NPO法人日本口腔科学会学術集会, May 2013.
226.	鎌田久美子, Keiko Kudoh, Masako Fujioka-Kobayashi, Nobuyuki Kuribayashi, Natsumi Takamaru, Go Ohe, Daisuke Uchida, Tetsuya Tamatani, Kenji Fujisawa, Hirokazu Nagai, 安田勝裕, 横山正秋 and Youji Miyamoto : 徳島県における口腔がん検診と口腔がん啓発のための活動状況, 第42回(公社)日本口腔外科学会中四国支部学術集会, Apr. 2013.
227.	Masako Fujioka-Kobayashi, Natsumi Takamaru, Tetsuya Tamatani, Daisuke Uchida, Go Ohe, Hirokazu Nagai and Youji Miyamoto : ナビゲーションシステムを用いて腫瘍切除を行い，腸骨移植とインプラントで再建した骨形成線維腫の1例, 第42回(公社)日本口腔外科学会中四国支部学術集会, Apr. 2013.
228.	木内誠, Daisuke Uchida, Nobuyuki Kuribayashi, Hirokazu Nagai, Tetsuya Tamatani and Youji Miyamoto : stromal-cell derived factor (SDF)-1/CXCR4システムにより誘導される口腔癌の転移関連マイクロRNAの同定, 第31回日本口腔腫瘍学会総会・学術大会, Jan. 2013.
229.	Nobuyuki Kuribayashi, Hirokazu Nagai, Daisuke Uchida, 木内誠, Tetsuya Tamatani, Kenji Fujisawa, Naozumi Ishimaru and Youji Miyamoto : 頬粘膜に生じた明細胞癌NOSの1例, 第31回日本口腔腫瘍学会総会・学術大会, Jan. 2013.
230.	原香苗, Hirokazu Nagai, 都留寛治, 石川邦夫 and Youji Miyamoto : ゼラチン複合型炭酸アパタイトフォームの創製, 日本バイオマテリアルシンポジウム2012, Nov. 2012.
231.	Takeshi Yamamoto, Go Ohe, Kenji Fujisawa, Hirokazu Nagai and Youji Miyamoto : ナビゲーションシステムを用いた下顎骨辺縁切除術後に骨移植とインプラント治療を行った骨形成線維腫の1例, 第32回日本口腔インプラント学会中国・四国支部学術大会, Nov. 2012.
232.	Youji Miyamoto : シンポジウムテーマ:「インプラントの光と影 ‐この10年とこれからの10年‐」私のインプラント治療の進化と淘汰, 第32回日本口腔インプラント学会中国・四国支部学術大会, Nov. 2012.
233.	Masako Fujioka-Kobayashi, Youji Miyamoto and 井関祥子 : 新規徐放性ナノゲルを用いたFGF18によるBMP2依存的な骨修復能の改良, 第57回公益社団法人日本口腔外科学会, Oct. 2012.
234.	Hirokazu Nagai, Kenji Fujisawa, Natsumi Takamaru, Daisuke Uchida, Tetsuya Tamatani, Go Ohe, Naozumi Ishimaru and Youji Miyamoto : 頬部に生じた粘液種の1例, 第57回公益社団法人日本口腔外科学会, Oct. 2012.
235.	Tetsuya Tamatani, Natsumi Takamaru, Nobuyuki Kuribayashi, Go Ohe, Daisuke Uchida, Hirokazu Nagai and Youji Miyamoto : 口腔扁平上皮癌におけるXIAPの発現に関する検討, 第57回公益社団法人日本口腔外科学会, Oct. 2012.
236.	Nobuyuki Kuribayashi, Daisuke Uchida, Makoto Kinouchi, Tetsuya Tamatani, Hirokazu Nagai and Youji Miyamoto : SDF-1/CXCR4システムを介した口腔癌のリンパ節転移におけるmGluR5の臨床病理学的意義, 第57回公益社団法人日本口腔外科学会, Oct. 2012.
237.	Masako Kobayashi, Youji Miyamoto and 井関祥子([東京医科歯科大学医歯学総合研究科分子発生学分野 : 新規徐放性ナノゲルを用いたFGF18によるBMP2依存的な骨修復能の改良, 第57回公益社団法人日本口腔外科学会, Oct. 2012.
238.	鈴木悠, Go Ohe, Natsumi Takamaru, Daisuke Uchida, Tetsuya Tamatani, Hirokazu Nagai and Youji Miyamoto : 抜歯後疼痛を対象としたセレコキシブの有効性および安全性の検討, 第60回NPO法人日本口腔科学会中国・四国地方部会, Oct. 2012.
239.	Nobuyuki Kuribayashi, Daisuke Uchida, Makoto Kinouchi, Tetsuya Tamatani, Kenji Fujisawa, Hirokazu Nagai and Youji Miyamoto : 口腔への転移性癌に関する臨床的検討, 第11回中国四国口腔癌研究会学術講演会, Oct. 2012.
240.	Kenji Fujisawa, Go Ohe, Daisuke Uchida, Hirokazu Nagai and Youji Miyamoto : 上部構造装着後のインプラント脱落症例の検討ー滑面と粗面インプラントの比較ー, 第42回日本口腔インプラント学会, Sep. 2012.
241.	Makoto Kinouchi, Daisuke Uchida, Nobuyuki Kuribayashi, Tetsuya Tamatani, Hirokazu Nagai and Youji Miyamoto : Role of mGluR5 on the lymph node metastases of oral cancer by the SDF-1/CXCR4 system in salivary gland adenoid cystic carcinoma, 第71回日本癌学会学術総会, Sep. 2012.
242.	Nobuyuki Kuribayashi, Daisuke Uchida, Makoto Kinouchi, Tetsuya Tamatani, Hirokazu Nagai and Youji Miyamoto : Role of mGluR5 on the lymph node metastases of oral cancer by the SDF-1/CXCR4 system, 第71回日本癌学会学術総会, Sep. 2012.
243.	Natsumi Takamaru, 鎌田久美子, Go Ohe, Daisuke Uchida, Tetsuya Tamatani, Kenji Fujisawa, Hirokazu Nagai and Youji Miyamoto : 口腔癌術後補助化学療法としてのS-1の短期成績, 第66回日本口腔科学会学術集会, May 2012.
244.	Go Ohe, 小出真理子, Natsumi Takamaru, Daisuke Uchida, Tetsuya Tamatani, Kenji Fujisawa, Hirokazu Nagai and Youji Miyamoto : 下顎枝垂直骨切り術のためのCTを用いた下顎枝形態の検討, 第66回日本口腔科学会学術集会, May 2012.
245.	原香苗, Hirokazu Nagai, Nobuyuki Kuribayashi, Takeshi Yamamoto, Natsumi Takamaru, Go Ohe, Daisuke Uchida, Tetsuya Tamatani, Kenji Fujisawa and Youji Miyamoto : 当科における悪性リンパ腫の臨床的検討, 第41回(社)日本口腔外科学会中・四国地方会, Apr. 2012.
246.	佐藤裕子, Natsumi Takamaru, Go Ohe, Daisuke Uchida, Tetsuya Tamatani, Kenji Fujisawa, Hirokazu Nagai and Youji Miyamoto : 当科におけるビスフォスフォネート関連顎骨壊死(BRONJ)患者の臨床的検討, 第41回(社)日本口腔外科学会中・四国地方会, Apr. 2012.
247.	Daisuke Uchida, Go Ohe, Nobuyuki Kuribayashi, Hirokazu Nagai and Youji Miyamoto : 抗血栓療法継続下にNd-YAGレーザーによる光凝固療法を行った舌血管腫の一例, 有病者歯科医療学会, Mar. 2012.
248.	Nobuyuki Kuribayashi, Daisuke Uchida, Tetsuya Tamatani, Hirokazu Nagai and Youji Miyamoto : ヒト唾液腺癌におけるケモカインレセプターCXCR4 の発現と機能的役割, The 30th Annual Meeting of Japan Society for Oral Tumors, Jan. 2012.
249.	Kenji Fujisawa, Go Ohe, Daisuke Uchida, Natsumi Takamaru, Tetsuya Tamatani, Hirokazu Nagai and Youji Miyamoto : ショートインプラントの生存率に関する臨床的検討, 第15回日本学顔面インプラント学会, Dec. 2011.
250.	Makoto Kinouchi, Kenji Fujisawa, Natsumi Takamaru, Go Ohe, Daisuke Uchida, Tetsuya Tamatani, Hirokazu Nagai, Shinji Fujihara, Eiji Tanaka and Youji Miyamoto : 下顎枝矢状分割骨切り術と下顎枝垂直骨切り術の術後安定性に関する検討, 第59回NPO法人日本口腔科学会中国・四国地方部会, Nov. 2011.
251.	小出真理子, Go Ohe, Natsumi Takamaru, Daisuke Uchida, Tetsuya Tamatani, Kenji Fujisawa, Hirokazu Nagai and Youji Miyamoto : 術前CTを用いた下顎枝の形態学的検討, 第59回NPO法人日本口腔科学会中国・四国地方部会, Oct. 2011.
252.	鎌田久美子, Natsumi Takamaru, Go Ohe, Daisuke Uchida, Tetsuya Tamatani, Kenji Fujisawa, Hirokazu Nagai and Youji Miyamoto : S-1による術後補助化学療法に関する検討, 第10回中四国口腔癌研究会学術講演会, Oct. 2011.
253.	Natsumi Takamaru, Hirokazu Nagai, Go Ohe, Daisuke Uchida, Tetsuya Tamatani, Naozumi Ishimaru and Youji Miyamoto : 下顎骨に発生した歯原性粘液腫の1例, 第 56回日本口腔外科学会総会・学術大会, Oct. 2011.
254.	Daisuke Uchida, Nobuyuki Kuribayashi, Tetsuya Tamatani, Hirokazu Nagai and Youji Miyamoto : SDF-1/CXCR4システムを介した口腔癌のリンパ節転移におけるmGluR5によるVEGFCの誘導, 第 56回日本口腔外科学会総会・学術大会, Oct. 2011.
255.	Emi Kawakami, Shinya Horiuchi, Rie Matsuda, Ryoko Uchida, Shingo Kuroda, Youji Miyamoto, 天真覚 and Eiji Tanaka : 骨格性開咬症に対する下顎骨の反時計方向を伴う外科的下顎骨移動術の長期安定性:15年経過症例, 第70回日本矯正歯科学会学術大会, 322, Oct. 2011.
256.	Emi Kawakami, Shinya Horiuchi, Rie Matsuda, Ryoko Uchida, Shingo Kuroda, Youji Miyamoto, 天真覚 and Eiji Tanaka : 骨格性開咬症に対する下顎骨の反時計方向を伴う外科的下顎骨移動術の長期安定性:15年経過症例, 第70回日本矯正歯科学会学術大会, Oct. 2011.
257.	Youji Miyamoto : 骨置換性の新規骨補填材料の開発-炭酸アパタイトの臨床応用に向けて-, 第31回日本口腔インプラント学会中国・四国支部総会・学術大会, Oct. 2011.
258.	Takeshi Yamamoto, Go Ohe, Kenji Fujisawa, Hirokazu Nagai and Youji Miyamoto : Experiences of implant operations using computer-aided surgery system, 第31回公益社団法人日本口腔インプラント学会中国・四国支部学術大会, Oct. 2011.
259.	Nobuyuki Kuribayashi, Daisuke Uchida, Tetsuya Tamatani, Hirokazu Nagai and Youji Miyamoto : stromal-cell derived factor (SDF)-1/CXCR4システムにより誘導される口腔癌における転移関連microRNAの同定, 第70回日本癌学会学術総会, Oct. 2011.
260.	Kenji Fujisawa, Go Ohe, Daisuke Uchida, Hirokazu Nagai and Youji Miyamoto : Clinico-statistical examination on prognosis of short implants, 第41回日本口腔インプラント学会, Vol.24, No.Specioal Issue, 242, Sep. 2011.
261.	Masako Fujioka-Kobayashi, 太田正人, 下田麻子, 秋吉一成, Youji Miyamoto and 井関祥子 : 新規徐放性ナノゲルを用いたFGF18によるBMP2依存的な骨修復能の改良, 第32回日本炎症・再生医学会, Jun. 2011.
262.	Masako Kobayashi, 太田正人, 下田麻子, 秋吉一成, Youji Miyamoto and 井関祥子 : 新規徐放性ナノゲルを用いたFGF18によるBMP2依存的な骨修復能の改良, 第32回日本炎症・再生医学会, Jun. 2011.
263.	佐藤裕子, Miwa Miyauchi, Daisuke Uchida, Natsumi Takamaru, Tetsuya Tamatani, Kenji Fujisawa, Hirokazu Nagai, Michiko Kubo, Chieko Sugawara, Akira Takahashi and Youji Miyamoto : 口腔扁平上皮癌の頸部リンパ節転移の診断におけるFDG-PET検査の有用性, 第40回(社)日本口腔外科学会中・四国地方会, May 2011.
264.	Takeshi Yamamoto, Daisuke Uchida, Nobuyuki Kuribayashi, Go Ohe, Tetsuya Tamatani, Kenji Fujisawa, Hirokazu Nagai and Youji Miyamoto : 舌対称性脂肪腫症の1例, 第40回(社)日本口腔外科学会中・四国地方会, May 2011.
265.	Miwa Miyauchi and Youji Miyamoto : ビスフォスフォネート関連顎骨壊死に関する最新の知見, 第38回四国歯学会例会, Mar. 2011.
266.	Kenji Fujisawa, Natsumi Takamaru, Keiko Kudoh, Go Ohe, Daisuke Uchida, Tetsuya Tamatani, Hirokazu Nagai and Youji Miyamoto : インプラント治療に関連したと思われるビスフォスフォネート製剤による顎骨壊死の2例, Japanese Journal of Maxillo Facial Implants, Vol.9, No.3, 86, Sep. 2010.
267.	Natsumi Takamaru, Tetsuya Tamatani, Daisuke Uchida, Shinya Horiuchi, Hirokazu Nagai, Eiji Tanaka and Youji Miyamoto : 最近，頭を悩ませた臨床症例その5∼片側性下顎頭過成長を伴う顔面非対称症例の治療経験, 四国歯学会第36回例会, Mar. 2010.
268.	Daisuke Uchida, Tomitaro Onoue, Go Ohe, Katsumi Motegi, Tetsuya Tamatani, 東雅之, Hirokazu Nagai and Youji Miyamoto : 最近，頭を悩ませた臨床症例(その4), Shikoku Dental Research, Vol.22, No.2, 205, 2010.
269.	Nobuyuki Kuribayashi, 佐々井明子, Tetsuya Tamatani, Tetsuya Yuasa, Keiko Kudoh, Kenji Fujisawa, Hirokazu Nagai and Youji Miyamoto : 当院における角化嚢胞性歯原性腫瘍の臨床的検討, Journal of The Japanese Stomatological Society, Vol.59, No.2, 89, 2010.
270.	藤岡真左子, Go Ohe, 茂木勝美, Daisuke Uchida, Tetsuya Tamatani, Hirokazu Nagai and Youji Miyamoto : 当科における最近5年間の顎顔面骨骨折の臨床統計的検討, Journal of The Japanese Stomatological Society, Vol.59, No.2, 92, 2010.
271.	Kenji Fujisawa, Tetsuya Yuasa, Go Ohe, Hirokazu Nagai and Youji Miyamoto : 即時荷重インプラントに関する臨床的検討 5年経過時の臨床成績, Journal of Japanese Society of Oral Implantology, Vol.23, 184, 2010.
272.	Natsumi Takamaru, Tetsuya Tamatani, Hirokazu Nagai and Youji Miyamoto : 下顎頭の片側性過成長による顔面非対称症例の治療経験, Japanese Journal of Oral & Maxillofacial Surgery, Vol.56, No.Suppl., 151, 2010.
273.	Nobuyuki Kuribayashi, Daisuke Uchida, Tetsuya Tamatani, Hirokazu Nagai and Youji Miyamoto : 頭頸部癌細胞株におけるCD44の癌幹細胞マーカーとしての検証, Japanese Journal of Oral & Maxillofacial Surgery, Vol.56, No.Suppl., 258, 2010.
274.	Natsumi Takamaru, Tetsuya Tamatani, Daisuke Uchida, Shinya Horiuchi, Hirokazu Nagai, Eiji Tanaka and Youji Miyamoto : 最近，頭を悩ませた臨床症例(その5) 片側性下顎頭過成長を伴う顔面非対称症例の治療経験, Shikoku Dental Research, Vol.23, No.2, 142, 2010.
275.	藤岡真左子, Go Ohe, Hirokazu Nagai, Daisuke Uchida, Tetsuya Tamatani and Youji Miyamoto : 唾液腺癌に対するバルプロ酸の抗腫瘍効果, Journal of The Japanese Stomatological Society, Vol.60, No.1, 126-127, 2010.
276.	Nobuyuki Kuribayashi, Daisuke Uchida, Tomitaro Onoue, Tetsuya Tamatani, Hirokazu Nagai and Youji Miyamoto : metabotropic glutamate receptor 5阻害剤による口腔扁平上皮癌の転移抑制, Journal of The Japanese Stomatological Society, Vol.60, No.1, 159, 2010.
277.	Tetsuya Tamatani, Natsumi Takamaru, Daisuke Uchida, Kenji Fujisawa, Hirokazu Nagai and Youji Miyamoto : 口腔扁平上皮癌におけるsurvivinの発現に関する検討, The Japanese Journal of Tissue Culture Society for Dental Research, Vol.20, No.1, 59-60, 2010.
278.	Hideyuki Takano, Kenji Fujisawa, Yukihiro Momota, Tetsuya Yuasa, Seiko Tatehara and Youji Miyamoto : 顎裂への骨移植部に対しインプラントによる補綴を行った3症例, Journal of Japanese Society of Oral Implantology, Vol.22, No.2, 206, Sep. 2009.
279.	Seiko Tatehara, Youji Miyamoto, Hirokazu Nagai, Kenji Fujisawa, Yukihiro Momota, Tetsuya Yuasa, Hideyuki Takano and 福田雅幸 : 低結晶性炭酸アパタイトの顎骨再建への応用に関する基礎的研究骨組織内での長期評価, Japanese Journal of Oral & Maxillofacial Surgery, Vol.55, No.Suppl., 286, Sep. 2009.
280.	Seiko Tatehara, Youji Miyamoto, Hirokazu Nagai, Kenji Fujisawa, Yukihiro Momota, Tetsuya Yuasa, Hideyuki Takano and 福田雅幸 : 低結晶性炭酸含有アパタイトの顎骨再建への応用に関する基礎的研究ウサギ大腿骨内での組織学的検討, Journal of The Japanese Stomatological Society, Vol.58, No.4, 223, Sep. 2009.
281.	Kenji Fujisawa, Tetsuya Yuasa, Seiko Tatehara, Yukihiro Momota, Hideyuki Takano, Eiji Yamauchi and Youji Miyamoto : 粗面インプラントのオッセオインテグレーション喪失症例の検討, Journal of Japanese Society of Oral Implantology, Vol.22, 191, Aug. 2009.
282.	Hideyuki Takano, Yukihiro Momota, Tetsuya Yuasa, Seiko Tatehara, Kenji Fujisawa and Youji Miyamoto : 低結晶性炭酸含有アパタイトの顎骨再建への応用に関する基礎的研究ウサギ上顎洞内での組織学的検討, Journal of Japanese Society of Oral Implantology, Vol.22, 261, Aug. 2009.
283.	Rie Matsuda, Shinya Horiuchi, Emi Kawakami, Hiroko Mori, Youji Miyamoto and Eiji Tanaka : 上顎縦骨折による咬合不全に対し，急速拡大装置を逆回転することで整復した1症例, 第52回中・四国矯正歯科学会学術大会, Jul. 2009.
284.	佐々井明子, Go Ohe, Daisuke Uchida, Tomitaro Onoue, Katsumi Motegi, Tetsuya Tamatani, Masayuki Azuma, Hirokazu Nagai and Youji Miyamoto : 口腔癌由来液性因子がOK-432による末梢血単核球のIFN-γ産生に与える影響, Journal of Japan Society for Oral Tumors, Vol.21, No.4, 342-343, 2009.
285.	Kenji Fujisawa, 武知正晃, 山内英嗣, Susumu Abe, 大塩恭仁, Youji Miyamoto, Fumiaki Kawano and 長山勝 : 共鳴振動数分析装置を用いたインプラント安定性の評価2一即時荷重インプラントにおけるImplant Stability Quotientの経時的変化-, Journal of Japanese Society of Oral Implantology, Vol.20, No.1, 123-124, Mar. 2007.
286.	南口知穂, Masaaki Takechi, Tetsuya Yuasa, Yukihiro Momota, Seiko Tatehara, Hideyuki Takano, 石川邦夫, Youji Miyamoto and Masaru Nagayama : 低結晶性炭酸アパタイト含有PLGA複合体が多核巨細胞に与える影響, 第60回日本口腔科学会総会, Jan. 2007. (Summary) 1
287.	Yukihiro Momota, Youji Miyamoto, 石川邦夫, Masaaki Takechi, Tetsuya Yuasa, 舘原誠晃, Hideyuki Takano, 南口知穂 and Masaru Nagayama : HAP Putty(骨止血剤)が血小板凝集および血小板由来増殖因子の分泌に及ぼす影響．, 第60回日本口腔科学会総会, Jan. 2007. (Summary) 1
288.	Seiko Tatehara, Masaaki Takechi, Yukihiro Momota, Tetsuya Yuasa, Hideyuki Takano, Youji Miyamoto and Masaru Nagayama : bFGF合浸Hap-PLGA複合体における骨組織反応について, 第50回(社)日本口腔外科学会総会, Sep. 2005. (Summary) 1
289.	南口知穂, Masaaki Takechi, Tetsuya Yuasa, Yukihiro Momota, Seiko Tatehara, Hideyuki Takano, Youji Miyamoto, Kazuhito Satomura and Masaru Nagayama : 骨組織再生におけるHAP-PLGA複合体の有用性に関する基礎研究, 第59回日本口腔科学会総会, Sep. 2005. (Summary) 1
290.	Yukihiro Momota, Youji Miyamoto, 石川邦夫, Masaaki Takechi, Tetsuya Yuasa, Seiko Tatehara, Hideyuki Takano, 南口知穂 and Masaru Nagayama : 骨止血剤(HAP putty)による血小板凝集能の亢進, Japanese Society of Oral and Maxillofacial Traumatology, Vol.4, No.1, 24-25, Jun. 2005.
291.	Hideyuki Takano, Youji Miyamoto, Kenji Fujisawa, Tetsuya Yuasa, Yukihiro Momota and Masaru Nagayama : 歯科インプラントのオッセオインテグレーション喪失に関する臨床統計学的検討, 第32回日本口腔外科学会中国四国地方部会, Jan. 2004. (Summary) 1
292.	山之内浩司, Youji Miyamoto, Yukihiro Momota, Keiko Kume and Nobuyuki Kamata : 舌体深部へのボディーピアス迷入の1例, 第31回日本口腔外科学会中・四国地方会, Jun. 2002. (Summary) 1
293.	Kenji Fujisawa, Youji Miyamoto, Seiko Tatehara, Masaaki Takechi, Yukihiro Momota, Tetsuya Yuasa, Masaru Nagayama, Kazuo Okura, Eiji Yamauchi, Motoharu Kori, 松浦広輿, Eiichi Bando and 池田隆志 : 眼窩エピテーゼの維持源にオッセオインテグレーティツドインプラントを応用した1例, 第21回日本口腔インプラント学会中国・四国支部総会・学術大会, 2001. (Summary) 1
294.	Youji Miyamoto, Kenji Fujisawa, Tetsuya Yuasa, Yukihiro Momota, Masaaki Takechi, Masaru Nagayama, Eiji Yamauchi, Eiichi Bando and Daisuke Hinode : 下顎無歯顎インプラント患者のオトガイ孔後方へのfixture埋入は是か非か?, 第31回日本口腔インプラント学会総会・学術大会, 2001. (Summary) 1
295.	Seiko Tatehara, Youji Miyamoto, Kenji Fujisawa, Masaaki Takechi, Yukihiro Momota, Tetsuya Yuasa, 増田尚子 and Masaru Nagayama : インプラント型仮骨延長器による垂直的歯槽骨延長の経験, 第46回(社)日本口腔外科学会総会, 2001. (Summary) 1
296.	Kenji Fujisawa, Youji Miyamoto, Masaaki Takechi, Yukihiro Momota, Tetsuya Yuasa, 藤武智, 増田尚子, Seiko Tatehara and Masaru Nagayama : ブローネマルクインプラントの臨床統計学的検討一上部構造装着後のフイクスチャー除去症例について-, 第55回日本口腔科学会総会, 2001. (Summary) 1
297.	Seiko Tatehara, Youji Miyamoto, Kenji Fujisawa, Masaaki Takechi, Yukihiro Momota, Tetsuya Yuasa, 藤武智, 飛梅悟, 増田尚子, Masaru Nagayama, Motoharu Kori, 松浦広輿, Eiji Yamauchi, Kazuo Okura and Daisuke Hinode : 当科におけるブローネマルクインプラントの臨床統計的検討-Osseointegration獲得に関与する因子について-, 第20回日本口腔インプラント学会中国・四国支部総会・学術大会, 2000. (Summary) 1
298.	合田大亮, Kenji Fujisawa, Youji Miyamoto, Masaaki Takechi, 林英司 and Masaru Nagayama : PLLA(ポリ-L-乳酸)メッシュトレイおよび新鮮自家腸骨海綿骨細片移植による下顎再建後にインプラントを応用した1例, 第20回日本口腔インプラント学会中国・四国支部総会・学術大会, 2000. (Summary) 1
299.	Youji Miyamoto, Masaaki Takechi, Yukihiro Momota, Tetsuya Yuasa, 藤武智, Masaru Nagayama and Masayuki Kon : カルシウム溶液処理によるチタン表面の改質と疑似体液中における挙動, 第45回日本口腔外科学会総会, 2000. (Summary) 1
300.	藤武智, Youji Miyamoto, Masaaki Takechi, Yukihiro Momota, Tetsuya Yuasa, Masaru Nagayama, 石川邦夫 and Kazuomi Suzuki : 炭酸水素ナトリウムを用いた骨置換型アパタイトセメントー培養破骨細胞による吸収性の評価-, 第45回日本口腔外科学会総会, 2000. (Summary) 1
301.	Masaaki Takechi, Youji Miyamoto, Kenji Fujisawa, Yukihiro Momota, Tetsuya Yuasa, 藤武智, Masaru Nagayama, 鈴木温 and Daisuke Hinode : 当科におけるインプラント失敗例に関する臨床的検討一上部構造装着前の失敗症例について一, 第30回日本口腔インプラント学会総会・学術大会, 2000. (Summary) 1
302.	Youji Miyamoto, Masaaki Takechi, Yukihiro Momota, Tetsuya Yuasa, 藤武智 and Masaru Nagayama : 急速アパタイト転換型リン酸カルシウムセメントの開発, 第30回日本口腔インプラント学会総会・学術大会, 2000. (Summary) 1
303.	山之内浩司, Kazuhito Satomura, Kenji Fujisawa, Youji Miyamoto, Masaru Nagayama and Katsuhiko Nakamura : 確定診断に至らなかった難治性口内炎の1例, 第10回日本口腔粘膜学会総会, 2000. (Summary) 1

Products:

1.	石川邦夫 and Youji Miyamoto : インプラント治療用人工骨「ジーシーサイトランスグラニュール®」の開発と臨床応用. Ⅰ.驚異の炭酸アパタイト人工骨補填材, Dental Diamond, Vol.43, No.9, 142-146, Sep. 2018.
2.	石川邦夫 and Youji Miyamoto : インプラント治療用人工骨「ジーシーサイトランスグラニュール®」の開発と臨床応用. Ⅱ. サイトランスグラニュール®の開発と臨床応用, Dental Diamond, Vol.49, No.3, 147-151, Aug. 2018.
3.	石川邦夫, Youji Miyamoto, 春日井昇平 and 古谷野潔 : 日本で初めてインプラントの併用が認可された骨補填材:サイトランス® グラニュールとは?, Quintessence DENTAL Implantology, Vol.25, No.4, 631-633, Jul. 2018.

Et cetera, Workshop:

1.	Youji Miyamoto : 新規骨補填材としての炭酸アパタイトの開発．-サイトランスグラニュール-, 結志会, Feb. 2019.
2.	Youji Miyamoto : 私の行っている大胸筋皮弁, 第6回岡山大学臨床解剖口腔外科手術手技研修会, Feb. 2019.
3.	Youji Miyamoto : 気管切開術, 第6回岡山大学臨床解剖口腔外科手術手技研修会, Feb. 2019.
4.	尾上真奈美, Kazumi Takaishi, Keiko Kudoh, Natsumi Takamaru, 鎌田久美子, 大塚良, Shigeki Fujiwara Joseph Luke, Satoru Eguchi, Youji Miyamoto and Hiroshi Kitahata : 根管治療後に下歯槽神経感覚障害が生じた1例, 第32回中国·四国歯科麻酔研究会, Jul. 2017.
5.	Youji Miyamoto : 口腔がん検診とは-全国の実施状況と徳島の現状-, 平成23年度徳島県歯科医師会四国歯学会合同シンポジウム「徳島県における口腔がん検診に向けて-わが国の口腔がん検診の現状-」, Sep. 2011.

Grants-in-Aid for Scientific Research (KAKEN Grants Database @ NII.ac.jp)

骨補填材兼GBR用スペーサー機能をもつ炭酸アパタイト／魚コラーゲンシートの開発 (Project/Area Number: 23K09372 )
Investigation of novel oral cancer-specific molecular targets based on genetic diversity (Project/Area Number: 23K24546 )
The identification of genes involved in the maintenance and regeneration of salivary gland stem / progenitor cells and application to new xerostomia treatment (Project/Area Number: 22K10121 )
Lubricinによる変形性顎関節症に対する新規治療法の開発 (Project/Area Number: 21K10096 )
感染制御と骨再生を同時に可能とするハイブリッド型骨補填材による顎骨骨髄炎治療戦略 (Project/Area Number: 21K10095 )
カーボネイトアパタイトの高い骨伝導能・骨再生能を細胞の分子メカニズムから解明する (Project/Area Number: 21H03139 )
Strategic bone reproduction using scaffold of porous carbonate apatite granules/fish-derived collagen composite (Project/Area Number: 20K10180 )
Establishment of visualizing oral cancer model and development of clinical ultrasonographic examination which detects initial cervical metastatic lymph node by oral cancer (Project/Area Number: 20K10140 )
Application in jaw bone reconstruction and bone regenerative medicine by uniaxially porous carbonate apatite (Project/Area Number: 19K10333 )
We elucidate the excellent osteoconductivity of hydroxyapatite (Project/Area Number: 19K10290 )
Prevention / medical treatment strategy by a blood vessel rebirth and osteogenic effect of establishment of a radiation nature jawbone necrosis model, and statin (Project/Area Number: 19K10268 )
Establishment of novel oral cancer stem cell model mimicking human oral cancer by reprogramming and insertion of gene mutation (Project/Area Number: 19H03853 )
Fabrication of a new spongiform elasticity bone substitue using carbonate apatite (Project/Area Number: 18K09815 )
3種類のサンプリングによるアレイ解析を用いた口腔癌のセツキシマブ耐性化機構の解明 (Project/Area Number: 18K09792 )
Elucidation of the expression and regulation mechanisms of Lubricin aiming at the development of a new treatment for osteoarthritis of the jaw (Project/Area Number: 18K09769 )
Development of prevention and treatment of medication-related osteonecrosis of the jaw by angiogenic and osteogenic effects of statins (Project/Area Number: 18K09746 )
Identification of Metastasis-specific miRNAs and Establishment of Diagnostic Methods Focusing on Cancer Stem Cells and Blood of Patients with Oral Cancer Metastasis (Project/Area Number: 18K09745 )
Fabrication of the bone and soft tissue regenerative medicine using porous carbonate apatite with replacement to new bone and blood vessels (Project/Area Number: 18H03002 )
Development of the bone regenerative medicine with the porous carbonate apatite made from calcium sulfate and bone marrow stem cell (Project/Area Number: 16K11752 )
The inducing differentiation of iPS cells and salivary gland regeneration that reproduces the epithelial-mesenchymal interaction in initiation stage (Project/Area Number: 16K11751 )
establishment of oral cancer animal model with bone invasion and development of clinical computed tomography examination which enable assessing mandibular invasion caused by oral cancer (Project/Area Number: 16K11505 )
Clarification of the mechanism of oral carcinogenesis by the defect of degradation of chromosome passenger complex protein (Project/Area Number: 16H05542 )
We investigate the essence of osseointegration and biointegration in the cell (Project/Area Number: 15K15741 )
Bone regeneration using a hybrid-type artificial bone consisted of iPS cells and low crystalline carbonate apatite (Project/Area Number: 15K11315 )
the examination of microRNA related with lymph node metastasis (Project/Area Number: 15K11294 )
Challenge of leptin as new healing accelerant for wound healing and intractable stomatitis (Project/Area Number: 15K11253 )
Role of miR-518c-5p on the metastasis of oral cancer via CXCR4 system (Project/Area Number: 26463046 )
Challenge of raiditoherapy for oral cancer -definition of appropriate combination both cetuximab and docetaxel- (Project/Area Number: 26462838 )
Promoting differentiation of osteoblasts from induced pluripotent stem (iPS) cells using scaffolds recreating the bone tissue microenvironment. (Project/Area Number: 25670859 )
Fabrication of gelatin-coated carbonate apatite foam and its application on reconstruction of jaw (Project/Area Number: 25463137 )
Development of the anticancer drug sensitivity testing and elucidation of the resistance mechanism for oral cancer using new cultural method CTOS (Project/Area Number: 25463110 )
Development of combination therapy, targeting NF-kB and CXCR4-related miRNA in oral cancer (Project/Area Number: 25293411 )
Analysis of PARP as nobel potencial therapeutic targets in oral cancer (Project/Area Number: 24593036 )
Development of tooth regenerative therapy using the interaction between immortalized odontogenic cell and iPS cells. (Project/Area Number: 24592989 )
The role of miRNA on the mechanism of metastasis induced by the SDF-1/CXCR4 system in oral cancer (Project/Area Number: 23592964 )
Improvement of the replacement of carbonate apatite to bone by the regulation of porous structure (Project/Area Number: 23390444 )
Establisment of differentiation method from induced pluripotent stem(iPS) cells to osteoblasts via mesenchymal stem cells (Project/Area Number: 22659370 )
Approach for porous calcium phosphate cement (Project/Area Number: 22659358 )
Sinus floor elevation put in ready-made spacer build up with low crystalline carbonate apatite and without bone graft (Project/Area Number: 22592260 )
Development of new oral cancer treatment as molecular target for antiapoptosis protein and NF-kB (Project/Area Number: 21592556 )
Development of tooth regenerative therapy applied molecular mechanisms of epithelial-mesenchymal interactions in tooth morphogenesis (Project/Area Number: 21592528 )
Study of mechanism of occurrence and increased risk factor of BRONJ (Project/Area Number: 21592386 )
Fabrication of cancel. ous bone type bone replacement (Project/Area Number: 20390500 )
ケイ酸カルシウム処理による骨伝導性制御 (Project/Area Number: 19659510 )
Development of tooth regenerative therapy using the low crystalline carbonate apatite and mesenchymal stem cells derivedfrom adipose tissue (Project/Area Number: 19592282 )
pplication to oral cancer of the sentinel lymph node identificationmethod using lymphangiography CT (Project/Area Number: 19592281 )
不死化歯由来細胞株と生体内吸収性材料を用いた歯の再生医療用スキャフォールドの開発 (Project/Area Number: 18659588 )
柔軟性を示す骨置換材の創製 (Project/Area Number: 18659578 )
Molecular biological analysis of bone metabolism by compressive mechanical stress in human synovial cells of the temporomandibular joint (Project/Area Number: 18592196 )
Applications of bone-replaceable carbonate spatife for jawbone recanstruetion and for scaffold of bone regeneration (Project/Area Number: 18390533 )
Fabrication of osteoclast-resorbable bone substitute (Project/Area Number: 18390517 )
Development of the cell transplantation therapy for the tooth regeneration using the committed progenitor cell of the tooth established from the tooth germ (Project/Area Number: 18300159 )
海綿骨の形態と組成を模倣した完全連通型骨置換材の創製 (Project/Area Number: 17659612 )
Analysis of the stress signaling pathway using synovial cells from human temporomandibular joint and application to a gene therapy. (Project/Area Number: 17592065 )
テーラーメイド医療を目指した傾斜機能型骨置換材に関する研究 (Project/Area Number: 16659537 )
Fabrication of scaffolds made of bioresorbable polymer for bone and cartilage regeneration and its bone reconstruction using transplantation with the blood vessel pattern. (Project/Area Number: 16592003 )
Elucidation of temporomandibular disorders using contrast-enhancement MRI and analysis of synovial fluid/tissue (Project/Area Number: 16591981 )
Fabrication of the high osteoconductive bone replacement (Project/Area Number: 16390559 )
Development of FRP composed by bioactive glass fiber and polymer for bone reconstruction (Project/Area Number: 15592053 )
アパタイトプレフォームの創製に関する研究 (Project/Area Number: 14657505 )
Effect of mechanical stress on the osteoblastic differentiation of human mesenchymal stem cell (Project/Area Number: 14571938 )
The development of apatite cement that has the enhanced speed of bone replacement (Project/Area Number: 14571897 )
Isolation of somatic stem cells from bone marrow stroma and peripheral blood, and their application for tissue regeneration (Project/Area Number: 14571895 )
Fabrication of bioresorbable porous ceramics for bone regeneration and its bone reconstruction using transplantation with the blood vessel pattern (Project/Area Number: 14571894 )
Estimation of osteointegration for calcium phosphate materials by immersion in simulated body fluid (Project/Area Number: 13672040 )
Study on the self-setting cell regulation membrane aimed for the tissue regeneration (Project/Area Number: 13470415 )
三次元骨梁構造セラミックスフォームの試作と骨内組織反応 (Project/Area Number: 12877315 )
bone replacement of apatite cement with the connected open pore (Project/Area Number: 11671992 )
Fabrication and histological evaluation of bone-replacing calcium phosphate cement using NaHCOィイD23ィエD2 (Project/Area Number: 10671885 )
Approach for bone replacing apaite cement (Project/Area Number: 09470438 )
骨置換性リン酸カルシウム・コーティング・チタンインプラントの試作と骨内反応 (Project/Area Number: 07857144 )
Development of Functionally Gradient Bioceramics Producing with Acid Treatment (Project/Area Number: 07672115 )
Application of anti-washout type fast-setting calcium phosphate cement for the reconstruction of jaw bone (Project/Area Number: 07557280 )
Studies on the tissue response to fast-setting calcium phosphate cement (Project/Area Number: 07557274 )
ラット可移植性口腔癌細胞の単クローン抗体作製と免疫電顕法による癌細胞動態の研究 (Project/Area Number: 06771920 )
傾斜機能バイオセラミックス多孔体の試作と生体内反応 (Project/Area Number: 06671955 )
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Professor Emeritus : Miyamoto, Youji

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