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Tokushima University > Graduate School of Biomedical Sciences > 歯学域 > Oral Science > Basic Dentistry > Department of Oral Molecular Pathology >
Tokushima University > Faculty of Dentistry > Course in Dentistry > Basic Oral Sciences > Oral Molecular Pathology >
Tokushima University > Research Clusters > Research Clusters (Prioritized) > 1702005 難病の克服を目指した免疫学研究の拠点形成 >
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Research Activity

Field of Study

Pathology, Immunology

Subject of Study

Molecular mechanism of autoimmune diseases (autoimmune, T cell activation, NF-kB, sex hormone, Sjögren's syndrome)

Book / Paper

Book:

1. Yosuke Shikama, Naozumi Ishimaru, Yasusei Kudo, Rieko Arakaki, Yukiko Bandou, Nanako Aki and Makoto Funaki :
High Levels of Saturated Fatty Acids may Exacerbate the Pathogenesis of Primary Sjögrens Syndrome,
Springer, Dec. 2014.
2. Yoshio Hayashi and Naozumi Ishimaru :
Handbook on Immunosenescence,
Springer Japan, Apr. 2009.
3. Yoshio Hayashi and Naozumi Ishimaru :
口唇腺生検病理診断 「シェーグレン症候群の診断と治療マニュアル」,
株式会社 診断と治療社, Tokyo, Apr. 2009.
4. Yoshio Hayashi and Naozumi Ishimaru :
Autoimmunity-Aging Mouse Model for Autoimmune Diseases,
Jan. 2009.
5. Naozumi Ishimaru, 岸本 英博 and Yoshio Hayashi :
T細胞レセプターシグナルとNF-κB,
2007.

Academic Paper (Judged Full Paper):

1. Aya Miyazaki, Asuna Sugimoto, Yoshizaki Keigo, Keita Kawarabayashi, Kokoro Iwata, Rika Kurogohshi, Takamasa Kitamura, Kunihiro Otsuka, Tomokazu Hasegawa, Yuki Akazawa, Fukumoto Satoshi, Naozumi Ishimaru and Tsutomu Iwamoto :
Coordination of WNT signaling and ciliogenesis during odontogenesis by piezo type mechanosensitive ion channel component 1,
Scientific Reports, Vol.9, 14762, 2019.
(DOI: 10.1038/s41598-019-51381-9)
2. Kunihiro Otsuka, Akiko Yamada, Masako Saito, Aya Ushio, Mami Sato, Satoru Kisoda, Wenhua Shao, Takaaki Tsunematsu, Yasusei Kudo, Rieko Arakaki and Naozumi Ishimaru :
Ascl2-Regulated Follicular Helper T Cells Promote Autoimmunity in a Murine Model for Sjögren's Syndrome.,
The American Journal of Pathology, 2019.
(DOI: 10.1016/j.ajpath.2019.08.008,   PubMed: 31539517,   Elsevier: Scopus)
3. Chihiro Nakatomi, Mitsushiro Nakatomi, Takuma Matsubara, Toshihisa Komori, Takahiro Doi-Inoue, Naozumi Ishimaru, Falk Weih, Tsutomu Iwamoto, Miho Matsuda, Shoichiro Kokabu and Eijiro Jimi :
Constitutive activation of the alternative NF-κB pathway disturbs endochondral ossification,
Bone, Vol.121, 29-41, 2019.
(DOI: 10.1016/j.bone.2019.01.002,   PubMed: 30611922,   Elsevier: Scopus)
4. Aya Ushio, Rieko Arakaki, Kunihiro Ohtsuka, Akiko Yamada, Takaaki Tsunematsu, Yasusei Kudo, Keiko Aota, Masayuki Azuma and Naozumi Ishimaru :
CCL22-Producing Resident Macrophages Enhance T Cell Response in Sjögren's Syndrome.,
Frontiers in Immunology, Vol.9, 2594, 2018.
(Tokushima University Institutional Repository: 113526,   DOI: 10.3389/fimmu.2018.02594,   PubMed: 30467506,   Elsevier: Scopus)
5. Kunihiro Ohtsuka, Kohichi Yamada, Yuhji Taquahashi, Rieko Arakaki, Aya Ushio, Masako Saito, Akiko Yamada, Takaaki Tsunematsu, Yasusei Kudo, Jun Kanno and Naozumi Ishimaru :
Long-term polarization of alveolar macrophages to a profibrotic phenotype after inhalation exposure to multi-wall carbon nanotubes.,
PLoS ONE, Vol.13, No.10, e0205702., 2018.
(Tokushima University Institutional Repository: 113527,   DOI: 10.1371/journal.pone.0205702,   PubMed: 30372450,   Elsevier: Scopus)
6. Keiko Aota, Kohichi Kani, Tomoko Yamanoi, Koh-ichi Nakashiro, Naozumi Ishimaru and Masayuki Azuma :
Distinct Regulation of CXCL10 Production by Cytokines in Human Salivary Gland Ductal and Acinar Cells.,
Inflammation, Vol.41, No.4, 1172-1181, 2018.
(Tokushima University Institutional Repository: 112923,   DOI: 10.1007/s10753-018-0764-0,   PubMed: 29549479,   Elsevier: Scopus)
7. Keiko Aota, Tomoko Yamanoi, Kohichi Kani, Koh-ichi Nakashiro, Naozumi Ishimaru and Masayuki Azuma :
Inverse correlation between the number of CXCR3+ macrophages and the severity of inflammatory lesions in Sjögren's syndrome salivary glands: a pilot study,
Journal of Oral Pathology & Medicine, Vol.47, No.7, 710-718, 2018.
(Tokushima University Institutional Repository: 113977,   DOI: 10.1111/jop.12756,   PubMed: 29926992,   Elsevier: Scopus)
8. Penkhae Utaijaratrasmi, Kulthida Vaeteewoottacharn, Takaaki Tsunematsu, Pranisa Jamjantra, Sopit Wongkham, Chawalit Pairojkul, Narong Khuntikeo, Naozumi Ishimaru, Yongyut Sirivatanauksorn, Ananya Pongpaibul, Peti Thuwajit, Chanitra Thuwajit and Yasusei Kudo :
The microRNA-15a-PAI-2 axis in cholangiocarcinoma-associated fibroblasts promotes migration of cancer cells.,
Molecular Cancer, Vol.17, No.1, 2018.
(Tokushima University Institutional Repository: 113571,   DOI: 10.1186/s12943-018-0760-x,   PubMed: 29347950)
9. Mie Kurosawa, Rieko Arakaki, Akiko Yamada, Takaaki Tsunematsu, Yasusei Kudo, J Sprent and Naozumi Ishimaru :
NF κB2 Controls the Migratory Activity of Memory T Cells by Regulating Expression of CXCR4 in a Mouse Model of Sjögren's Syndrome,
Arthritis & Rheumatology, Vol.69, No.11, 2193-2202, 2017.
(Tokushima University Institutional Repository: 111719,   DOI: 10.1002/art.40230,   PubMed: 28804991,   Elsevier: Scopus)
10. Hidesuke Tada, Natsumi Fujiwara, Takaaki Tsunematsu, Yoshiko Tada, Rieko Arakaki, Naofumi Tamaki, Naozumi Ishimaru and Yasusei Kudo :
Preventive effects of mouthguard use while sleeping on recurrent aphthous stomatitis: Preliminary interventional study.,
Clinical and Experimental Dental Research, Vol.3, No.5, 198-203, 2017.
(Tokushima University Institutional Repository: 113573,   DOI: 10.1002/cre2.88,   PubMed: 29744201)
11. Takashi Izawa, Rieko Arakaki and Naozumi Ishimaru :
Role of Fas and RANKL signaling in peripheral immune tolerance,
Journal of Clinical & Cellular Immunology, Vol.8, No.4, 512, 2017.
(DOI: 10.4172/2155-9899.1000512)
12. Mina Kozai, Yuki Kubo, Tomoya Katakai, Hiroyuki Kondo, Hiroshi Kiyonari, Karin Schaeuble, Sanjiv A. Luther, Naozumi Ishimaru, Izumi Ohigashi and Yousuke Takahama :
Essential role of CCL21 in establishment of central self-tolerance in T cells,
The Journal of Experimental Medicine, Vol.214, No.7, 1925-1935, 2017.
(Tokushima University Institutional Repository: 110168,   DOI: 10.1084/jem.20161864,   PubMed: 28611158)
13. Aya Ushio, Rieko Arakaki, Hiroshi Eguchi, Fumika Hotta, Akiko Yamada, Yasusei Kudo and Naozumi Ishimaru :
Pathological Analysis of Ocular Lesions in a Murine Model of Sjögren's Syndrome.,
International Journal of Molecular Sciences, Vol.18, No.6, 2017.
(Tokushima University Institutional Repository: 110971,   DOI: 10.3390/ijms18061209,   PubMed: 28587293)
14. Takashi Izawa, Rieko Arakaki and Naozumi Ishimaru :
Crosstalk between cytokine RANKL and AhR signaling in osteoclasts controls bone homeostasis,
Journal of Cytokine Biology, Vol.2, No.2, 114, 2017.
(DOI: 10.4172/2576-3881.1000114)
15. Yosuke Shikama, Yasusei Kudo, Naozumi Ishimaru and Makoto Funaki :
Potential Role of Free Fatty Acids in the Pathogenesis of Periodontitis and Primary Sjögren's Syndrome.,
International Journal of Molecular Sciences, Vol.18, No.4, 2017.
(Tokushima University Institutional Repository: 112408,   DOI: 10.3390/ijms18040836,   PubMed: 28420093)
16. Satoko Kujiraoka, Takaaki Tsunematsu, Yukiko Sato, Maki Yoshida, Ayataka Ishikawa, Rei Tohyama, Michio Tanaka, Yutaka Kobayashi, Tomoyuki Kondo, Aya Ushio, Kunihiro Otsuka, Mie Kurosawa, Masako Saito, Akiko Yamada, Rieko Arakaki, Hirokazu Nagai, Hiromasa Nikai, Kengo Takeuchi, Toshitaka Nagao, Youji Miyamoto, Naozumi Ishimaru and Yasusei Kudo :
Establishment and characterization of a clear cell odontogenic carcinoma cell line with EWSR1-ATF1 fusion gene.,
Oral Oncology, Vol.69, 46-55, 2017.
(Tokushima University Institutional Repository: 111726,   DOI: 10.1016/j.oraloncology.2017.04.003,   PubMed: 28559020)
17. Akiko Yamada, Rieko Arakaki, Masako Saito, Yasusei Kudo and Naozumi Ishimaru :
Dual Role of Fas/FasL-Mediated Signal in Peripheral Immune Tolerance.,
Frontiers in Immunology, Vol.8, No.403, 2017.
(Tokushima University Institutional Repository: 110975,   DOI: 10.3389/fimmu.2017.00403,   PubMed: 28424702)
18. Takashi Izawa, Rieko Arakaki, Hiroki Mori, Takaaki Tsunematsu, Yasusei Kudo, Eiji Tanaka and Naozumi Ishimaru :
The nuclear receptor AhR controls bone homeostasis by regulating osteoclast differentiation via the RANK/c-Fos signaling axis.,
The Journal of Immunology, Vol.197, No.12, 4639-4650, 2016.
(DOI: 10.4049/jimmunol.1600822,   PubMed: 27849171)
19. Takaaki Tsunematsu, Natsumi Fujiwara, Maki Yoshida, Yukihiro Takayama, Satoko Kujiraoka, Guangying Qi, Masae Kitagawa, Tomoyuki Kondo, Akiko Yamada, Rieko Arakaki, Mutsumi Miyauchi, Ikuko Ogawa, Yoshihiro Abiko, Hiroki Nikawa, Shinya Murakami, Takashi Takata, Naozumi Ishimaru and Yasusei Kudo :
Human odontogenic epithelial cells derived from epithelial rests of Malassez possess stem cell properties.,
Laboratory Investigation; a Journal of Technical Methods and Pathology, 2016.
(Tokushima University Institutional Repository: 113576,   DOI: 10.1038/labinvest.2016.85,   PubMed: 27479086)
20. Chieko Sugawara, Akira Takahashi, Fumiaki Kawano, Yasusei Kudo, Naozumi Ishimaru and Youji Miyamoto :
Intraoral Ultrasonography of Tongue Mass Lesions,
Dento Maxillo Facial Radiology, Vol.45, No.5, 20150362, 2016.
(Tokushima University Institutional Repository: 111906,   DOI: 10.1259/dmfr.20150362,   PubMed: 26915405)
21. Akiko Yamada, Aya Ushio, Rieko Arakaki, Takaaki Tsunematsu, Yasusei Kudo, Yoshio Hayashi and Naozumi Ishimaru :
Impaired expansion of regulatory T cells in a neonatal thymectomy-induced autoimmune mouse model.,
The American Journal of Pathology, Vol.185, No.11, 2886-2897, 2015.
(Tokushima University Institutional Repository: 113529,   DOI: 10.1016/j.ajpath.2015.07.007,   PubMed: 26343329)
22. Takaaki Tsunematsu, Rieko Arakaki, Akiko Yamada, Naozumi Ishimaru and Yasusei Kudo :
The non-canonical role of Aurora-A in DNA replication.,
Frontiers in Oncology, Vol.96, No.4, 468-480, 2015.
(Tokushima University Institutional Repository: 110980,   DOI: 10.3389/fonc.2015.00187,   PubMed: 26380219)
23. Tomomi Sano, Misaki Iwashita, Nagayasu Nagayasu, Akiko Yamashita, Takanori Shinjo, Atsushi Hashikata, Tomoichiro Asano, Akifumi Kushiyama, Naozumi Ishimaru, Yousuke Takahama and Fusanori Nishimura :
Protection from diet-induced obesity and insulin resistance in mice lacking CCL19-CCR7 signaling.,
Obesity, Vol.23, No.7, 1460-1471, 2015.
(DOI: 10.1002/oby.21127,   PubMed: 26097021,   Elsevier: Scopus)
24. Tomoyoshi Yamano, J Nedjic, M Hinteberger, S Koser, S Pinto, N Gerdes, E Lutgens, Naozumi Ishimaru, M Busslinger, B Brors, B Kyewski and L Klein :
Intrathymic B cell licensing for Aire expression and T cell tolerance induction.,
Immunity, Vol.42, No.6, 1048-1061, 2015.
(DOI: 10.1016/j.immuni.2015.05.013,   PubMed: 26070482,   Elsevier: Scopus)
25. Yosuke Shikama, Yasusei Kudo, Naozumi Ishimaru and Makoto Funaki :
Possible involvement of palmitate in pathogensis of periodontitis.,
Journal of Cellular Physiology, Vol.230, No.12, 2981-2989, 2015.
(DOI: 10.1002/jcp.25029,   PubMed: 25921577,   Elsevier: Scopus)
26. Nurul Md. Islam, Shinsuke Itoh, Takeshi Yanagita, Kumi Sumiyoshi, Satoru Hayano, Koh-Ichi Kuremoto, Hiroshi Kurosaka, Tadashi Honjo, Noriaki Kawanabe, Hiroshi Kamioka, Takayoshi Sakai, Naozumi Ishimaru, Ichiro Taniuchi and Takashi Yamashiro :
Runx/Cbfb signaling regulates postnatal development of granular convoluted tubule in the mouse submandibular gland.,
Developmental Dynamics, Vol.244, No.3, 488-496, 2015.
(DOI: 10.1002/dvdy.24231,   PubMed: 25410786,   Elsevier: Scopus)
27. Akihiko Iwasa, Rieko Arakaki, Naoko Honma, Aya Ushio, Akiko Yamada, Tomoyuki Kondo, Emi Kurosawa, Satoko Kujiraoka, Takaaki Tsunematsu, Yasusei Kudo, Eiji Tanaka, Noriko Yoshimura, Nobuhiro Harada, Yoshio Hayashi and Naozumi Ishimaru :
Aromatase controls Sjögren syndrome-like lesions through monocyte chemotactic protein-1 in target organ and adipose tissue-associated macrophages.,
The American Journal of Pathology, Vol.185, No.1, 151-161, 2015.
(Tokushima University Institutional Repository: 113532,   DOI: 10.1016/j.ajpath.2014.09.006,   PubMed: 25447050,   Elsevier: Scopus)
28. Chieko Sugawara, Akira Takahashi, Fumiaki Kawano, Takaharu Kudoh, Akiko Yamada, Naozumi Ishimaru, Hara Kanae and Youji Miyamoto :
Neuroendocrine tumor in the mandible: a case report with imaging and histopathologic findings,
Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology, Vol.119, No.1, e41-e48, 2015.
(DOI: 10.1016/j.oooo.2014.09.024,   PubMed: 25459356,   Elsevier: Scopus)
29. Rieko Arakaki, Hiroshi Eguchi, Akiko Yamada, Yasusei Kudo, Akihiko Iwasa, Enkhmaa Tserennadmid, Hotta Fumika, Mitamura-Aizawa Sayaka, Yoshio Hayashi and Naozumi Ishimaru :
Anti-Inflammatory Effects of Rebamipide Eyedrop Administration on Ocular Lesions in a Murine Model of Primary Sjögren's Syndrome.,
PLoS ONE, Vol.9, No.5, e98390, 2014.
(Tokushima University Institutional Repository: 110973,   DOI: 10.1371/journal.pone.0098390,   PubMed: 24866156,   Elsevier: Scopus)
30. Ashrin Nur Meinar, Rieko Arakaki, Akiko Yamada, Tomoyuki Kondo, Mie Kurosawa, Yasusei Kudo, Megumi Watanabe, Tetsuo Ichikawa, Yoshio Hayashi and Naozumi Ishimaru :
A critical role for thymic stromal lymphopoietin in nickel-induced allergy in mice.,
The Journal of Immunology, Vol.192, No.9, 4025-4031, 2014.
(DOI: 10.4049/jimmunol.1300276,   PubMed: 24670797,   Elsevier: Scopus)
31. Kouta Yano, Christine Carter, Naofumi Yoshida, Takaya Abe, Akiko Yamada, Takeshi Nitta, Naozumi Ishimaru, Kensuke Takada, W Geoffrey Butcher and Yousuke Takahama :
Gimap3 and Gimap5 cooperate to maintain T-cell numbers in the mouse.,
European Journal of Immunology, Vol.44, No.2, 561-572, 2014.
(DOI: 10.1002/eji.201343750,   PubMed: 24510501,   Elsevier: Scopus)
32. Tomokazu Hasegawa, Yuki Akazawa, Hirokazu Nagai, Takamasa Kitamura, Naozumi Ishimaru, Kimiko Ueda Yamaguchi, Hiroshi Nakagawa, Yukiko Kori, Aimi Yamamoto and Tsutomu Iwamoto :
Capillary Hemangioma on Palate of Infant:Case Report,
The Japanese Journal of Pediatric Dentistry, Vol.52, No.3, 448-453, 2014.
(DOI: 10.11411/jspd.52.3_448,   CiNii: 130005084435)
33. Keiko Aota, Yoshiko Yamamura, Kohichi Kani, Hideyuki Takano, Katsumi Motegi, Yukihiro Momota, Naozumi Ishimaru and Masayuki Azuma :
Prevention of the destruction of acinar structure in patients with Sjogren's syndrome : Clinicopathological study on the effectiveness of cepharanthin,
Journal of The Japanese Stomatological Society, Vol.62, No.4, 254-261, 2013.
(CiNii: 40019834188)
34. Emi Kawakami, Nobuhiko Kawai, Nao Kinouchi, Hiroyo Mori, Yutaka Ohsawa, Naozumi Ishimaru, Yoshihide Sunada, Sumihare Noji and Eiji Tanaka :
Local applications of myostatin-siRNA with atelocollagen increase skeletal muscle mass and recovery of muscle function.,
PLoS ONE, Vol.8, No.5, 2013.
(DOI: 10.1371/journal.pone.0064719,   PubMed: 23717655)
35. Natsumi Shimizu, Izumi Nakako Nakajima, Takaaki Tsunematsu, Ikuko Ogawa, Hidehiko Kawai, Ryoichi Hirayama, Akira Fujimori, Akiko Yamada, Ryuichi Okayasu, Naozumi Ishimaru, Takashi Takata and Yasusei Kudo :
Selective enhancing effect of early mitotic inhibitor 1 depletion on the sensitivity of doxorubicin or X-ray treatment in human cancer cells.,
The Journal of Biological Chemistry, 2013.
(Tokushima University Institutional Repository: 113579,   DOI: 10.1074/jbc.M112.446351,   PubMed: 23645673)
36. Yosuke Shikama, Naozumi Ishimaru, Yasusei Kudo, Yukiko Bandou, N Aki, Yoshio Hayashi and Makoto Funaki :
Effects of Free Fatty Acids on Human Salivary Gland Epithelial Cells.,
Journal of Dental Research, Vol.92, No.6, 540-546, 2013.
(DOI: 10.1177/0022034513487378,   PubMed: 23603335)
37. Ritsuko 徳永 律子 Oura, Rieko Arakaki, Akiko Yamada, Yasusei Kudo, Eiji Tanaka, Yoshio Hayashi and Naozumi Ishimaru :
Induction of Rapid T Cell Death and Phagocytic Activity by Fas-Deficient lpr Macrophages.,
The Journal of Immunology, 2013.
(DOI: 10.4049/jimmunol.1103794,   PubMed: 23255359)
38. Takaaki Tsunematsu, Yoshihiro Takihara, Naozumi Ishimaru, Michele Pagano, Takashi Takata and Yasusei Kudo :
Aurora-A controls pre-replicative complex assembly and DNA replication by stabilizing geminin in mitosis.,
Nature Communications, Vol.4, 2013.
(Tokushima University Institutional Repository: 113580,   DOI: 10.1038/ncomms2859,   PubMed: 23695679)
39. Takashi Izawa, Tomoyuki Kondo, Mie Kurosawa, Ritsuko 徳永 律子 Oura, Kazuma Matsumoto, Eiji Tanaka, Akiko Yamada, Rieko Arakaki, Yasusei Kudo, Yoshio Hayashi and Naozumi Ishimaru :
Fas-Independent T-Cell Apoptosis by Dendritic Cells Controls Autoimmune Arthritis in MRL/lpr Mice,
PLoS ONE, Vol.7, No.12, e48798, 2012.
(Tokushima University Institutional Repository: 110974,   DOI: 10.1371/journal.pone.0048798,   PubMed: 23300516)
40. Natsumi Takamaru, Daisuke Uchida, Go Ohe, Hirokazu Nagai, Naozumi Ishimaru and Youji Miyamoto :
下顎小臼歯部に発生した骨形成を伴う巨細胞エプーリスの1例,
Japanese Journal of Oral & Maxillofacial Surgery, Vol.58, No.11, 651-654, 2012.
(CiNii: 40019499475)
41. Chieko Sugawara, Akira Takahashi, Michiko Kubo, Hideki Otsuka, Naozumi Ishimaru, Youji Miyamoto and Eiichi Honda :
Preoperative evaluation of patients with squamous cell carcinoma of the oral cavity: fluorine-18 fluorodeoxyglucose positron emission tomography/computed tomography and ultrasonography versus histopathology.,
Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology, Vol.114, No.4, 516-525, 2012.
(DOI: 10.1016/j.oooo.2012.06.004,   PubMed: 22986248)
42. Yasusei Kudo, Shinji Iizuka, Maki Yoshida, Takaaki Tsunematsu, Tomoyuki Kondo, Ajiravudh Subarnbhesaj, Mohamed Elsayed Deraz, Bsm Samadarani Siriwardena, Hidetoshi Tahara, Naozumi Ishimaru, Ikuko Ogawa and Takashi Takata :
Matrix metalloproteinase-13 (MMP-13) directly and indirectly promotes tumor angiogenesis.,
The Journal of Biological Chemistry, 2012.
(Tokushima University Institutional Repository: 113581,   DOI: 10.1074/jbc.M112.373159,   PubMed: 22992737)
43. Yasusei Kudo, Shinji Iizuka, Maki Yoshida, Thao Phuong Nguyen, M Samadarani B S Siriwardena, Takaaki Tsunematsu, Mariko Ohbayashi, Toshinori Ando, Daijiro Hatakeyama, Toshiyuki Shibata, Keiichi Koizumi, Masahiro Maeda, Naozumi Ishimaru, Ikuko Ogawa and Takashi Takata :
Periostin directly and indirectly promotes tumor lymphangiogenesis of head and neck cancer.,
PLoS ONE, Vol.7, No.8, e44488, 2012.
(Tokushima University Institutional Repository: 113582,   DOI: 10.1371/journal.pone.0044488,   PubMed: 22952986)
44. Naozumi Ishimaru, Akiko Yamada, Takeshi Nitta, Rieko Arakaki, Martin Lipp, Yousuke Takahama and Yoshio Hayashi :
CCR7 with S1P1 signaling through AP-1 for migration of Foxp3+ regulatory T-cells controls autoimmune exocrinopathy.,
The American Journal of Pathology, Vol.180, No.1, 199-208, 2012.
(DOI: 10.1016/j.ajpath.2011.09.027,   PubMed: 22067914)
45. Megumi Watanabe, Naozumi Ishimaru, Meinar Nur Ashrin, Rieko Arakaki, Akiko Yamada, Tetsuo Ichikawa and Yoshio Hayashi :
A Novel DC Therapy with Manipulation of MKK6 Gene on Nickel Allergy in Mice,
PLoS ONE, Vol.6, No.4, E19017, 2011.
(DOI: 10.1371/journal.pone.0019017,   PubMed: 21544193)
46. T Yamano, S Watanabe, H Hasegawa, T Suzuki, R Abe, H Tahara, T Nitta, Naozumi Ishimaru, J Sprent and H Kishimoto :
Ex-vivo expanded DC induce donor-specific central and peripheral tolerance and prolong the acceptance of donor skin allografts.,
Blood, Vol.117, No.9, 2640-2648, 2011.
(DOI: 10.1182/blood-2010-07-293860,   PubMed: 21220748)
47. Yu Lei, Adiratna Mat Ripen, Naozumi Ishimaru, Izumi Ohigashi, Takashi Nagasawa, Lukas T. Jeker, Michael R. Bösl, Georg A. Holländer, Yoshio Hayashi, Rene Waal de Malefyt, Takeshi Nitta and Yousuke Takahama :
Aire-dependent production of XCL1 mediates medullary accumulation of thymic dendritic cells and contributes to regulatory T cell development,
The Journal of Experimental Medicine, Vol.208, No.2, 383-394, 2011.
(DOI: 10.1084/jem.20102327,   PubMed: 21300913)
48. Emi Kawakami, Nao Kinouchi, Taro Adachi, Yutaka Ohsawa, Naozumi Ishimaru, Hideyo Ohuchi, Yoshihide Sunada, Yoshio Hayashi, Eiji Tanaka and Sumihare Noji :
Atelocollagen-mediated systemic administration of myostatin-targeting siRNA improves muscular atrophy in caveolin-3-deficient mice.,
Development Growth & Differentiation, Vol.53, No.1, 48-54, 2011.
(DOI: 10.1111/j.1440-169X.2010.01221.x,   PubMed: 21261610)
49. Taro Adachi, Emi Kawakami, Naozumi Ishimaru, Takahiro Ochiya, Yoshio Hayashi, Hideyo Ohuchi, Masao Tanihara, Eiji Tanaka and Sumihare Noji :
Delivery of small interfering RNA with a synthetic collagen poly(Pro-Hyp-Gly) for gene silencing in vitro and in vivo.,
Development Growth & Differentiation, Vol.52, No.8, 693-699, 2010.
(DOI: 10.1111/j.1440-169X.2010.01206.x,   PubMed: 20874713)
50. Takashi Sakai, Li Liu, Xichuan Teng, Naozumi Ishimaru, Rika Mukai-Sakai, HoangNam Tran, Sun Mi Kim, Nobuya Sano, Yoshio Hayashi, Ryuji Kaji and Kiyoshi Fukui :
Inflammatory disease and cancer with a decrease in Kupffer cell numbers in Nucling-knockout mice.,
International Journal of Cancer, Vol.126, No.5, 1079-1094, 2010.
(DOI: 10.1002/ijc.24789,   PubMed: 19637241,   Elsevier: Scopus)
51. Seiko Tatehara, Kenji Fujisawa, Hirokazu Nagai, Shuji Shigemoto, Kazuo Okura, Naozumi Ishimaru, Yoshio Hayashi and Youji Miyamoto :
切除からインプラントを維持源としたエピテーゼまで一貫治療を行った上顎洞悪性線維性組織球腫の1例,
Shikoku Dental Research, Vol.22, No.2, 179-183, 2010.
(Tokushima University Institutional Repository: 109796)
52. Naozumi Ishimaru, 小橋 真之, Akiko Yamada, Rieko Arakaki and Yoshio Hayashi :
新生児におけるダイオキシンへの曝露と自己免疫病の発生,
Clinical Immunology & Allergology, Vol.53, No.1, 92-96, 2010.
(CiNii: 40016992928)
53. Naozumi Ishimaru, Takeshi Nitta, Rieko Arakaki, Akiko Yamada, Martin Lipp, Yousuke Takahama and Yoshio Hayashi :
In situ Patrolling of Regulatory T cells is Essential for Protecting Autoimmune Exocrinopathy,
PLoS ONE, Vol.5, No.1, e8588, 2010.
(DOI: 10.1371/journal.pone.0008588,   PubMed: 20052419)
54. Akiko Yamada, Naozumi Ishimaru, Rieko Arakaki, Nobuhiko Katsunuma and Yoshio Hayashi :
Cathepsin L inhivition prevents murine autoimmune diabetes via suppression of CD8+ T cell activity.,
PLoS ONE, Vol.5, No.9, e12894, 2010.
(DOI: 10.1371/journal.pone.0012894,   PubMed: 20877570)
55. Takeshi Nitta, Shigeo Murata, Katsuhiro Sasaki, Hideki Fujii, Adiratna Mat Ripen, Naozumi Ishimaru, Shigeo Koyasu, Keiji Tanaka and Yousuke Takahama :
Thymoproteasome shapes immunocompetent repertoire of CD8+ T cells.,
Immunity, Vol.32, No.1, 29-40, 2010.
(DOI: 10.1016/j.immuni.2009.10.009,   PubMed: 20045355)
56. Yoshio Hayashi, Rieko Arakaki and Naozumi Ishimaru :
Salivary gland and autoimmunity,
The Journal of Medical Investigation : JMI, Vol.56, 185-191, 2009.
(Tokushima University Institutional Repository: 111327,   DOI: 10.2152/jmi.56.185,   PubMed: 20224179)
57. Yoshio Hayashi, Naozumi Ishimaru and Rieko Arakaki :
シェーグレン症候群,
感染・炎症・免疫, Vol.39, No.3, 252-254, 2009.
58. Naozumi Ishimaru and Yoshio Hayashi :
Sjögren症候群の発症とエストロゲン,
Clinical Immunology, Vol.52, No.4, 431-437, 2009.
59. Kimi Yamakoshi, Akiko Takahashi, Fumiko Hirota, Rika Nakayama, Naozumi Ishimaru, Yoshiaki Kubo, J. David Mann, Masako Ohmura, Atsushi Hirao, Hideyuki Saya, Seiji Arase, Yoshio Hayashi, Kazuki Nakao, Mitsuru Matsumoto, Naoko Ohtani and Eiji Hara :
Real-time in vivo imaging of p16Ink4a reveals cross-talk with p53,
The Journal of Cell Biology, Vol.186, No.3, 393-407, 2009.
(DOI: 10.1083/jcb.200904105,   PubMed: 19667129)
60. Takeo Iwata, Masamichi Kuwajima, Akiko Sukeno, Naozumi Ishimaru, Yoshio Hayashi, Martin Wabitsch, Noriko Mizusawa, Mitsuo Itakura and Katsuhiko Yoshimoto :
YKL-40 secreted from adipose tissue inhibits degradation of type I collagen.,
Biochemical and Biophysical Research Communications, Vol.388, No.3, 511-516, 2009.
(Tokushima University Institutional Repository: 109641,   DOI: 10.1016/j.bbrc.2009.08.024,   PubMed: 19666003)
61. Naozumi Ishimaru, Takagi Atuya, Kohashi Masayuki, Akiko Yamada, Rieko Arakaki, Kanno Jun and Yoshio Hayashi :
Neonatal Exposure to Loe-Dose 2.3.7.8-Tetrachlorodibenzo-p-Dioxin Causes Autoimmunity Due to the Disruption of TCell Tolerance1,
The Journal of Immunology, Vol.182, No.10, 6576-6586, 2009.
(DOI: 10.4049/jimmunol.0802289,   PubMed: 19414813)
62. Rieko Arakaki, Ai Nagaoka, Naozumi Ishimaru, Akiko Yamada, Y Satoko and Yoshio Hayashi :
Role of Plasmacytoid Dendric Cells for Aberrant Class Expression in Exocrine Glands from Estrogen-Deficient Mice of healthy Background,
The American Journal of Pathology, Vol.174, No.5, 1715-1724, 2009.
(DOI: 10.2353/ajpath.2009.080695,   PubMed: 19359524)
63. Naozumi Ishimaru, Rieko Arakaki, Satoko Yoshida, Akiko Yamada, Sumihare Noji and Yoshio Hayashi :
Expression of the retinoblastoma protein RbAp48 in exocrine glands leads to Sjögren's syndrome-like autoimmune exocrinopathy.,
The Journal of Experimental Medicine, Vol.205, No.12, 2915-2927, 2008.
(DOI: 10.1084/jem.20080174,   PubMed: 19015307)
64. Yu Hikosaka, Takeshi Nitta, Izumi Ohigashi, Kouta Yano, Naozumi Ishimaru, Yoshio Hayashi, Mitsuru Matsumoto, Koichi Matsuo, Josef M Penninger, Hiroshi Takayanagi, Yoshifumi Yokota, Hisakata Yamada, Yasunobu Yoshikai, Jun-ichiro Inoue, Taishin Akiyama and Yousuke Takahama :
The cytokine RANKL produced by positively selected thymocytes fosters medullary thymic epithelial cells that express autoimmune regulator.,
Immunity, Vol.29, No.3, 438-450, 2008.
(DOI: 10.1016/j.immuni.2008.06.018,   PubMed: 18799150)
65. 中野 誠一, 山本 元久, 嶽村 貞治, Naozumi Ishimaru, Katsushi Miyazaki, Koichi Tamura, 氷見 徹夫, Yoshio Hayashi and Noriaki Takeda :
Three Cases of Mikulicz's Disease as an IgG4-related Disease,
Practica Oto-Rhino-Laryngologica, Vol.101, No.8, 591-597, 2008.
(DOI: 10.5631/jibirin.101.591,   CiNii: 10021940832,   Elsevier: Scopus)
66. Nao Kinouchi, Yutaka Ohsawa, Naozumi Ishimaru, Hideyo Ohuchi, Y Sunada, Yoshio Hayashi, Yukiho Tanimoto, Keiji Moriyama and Sumihare Noji :
Atelocollagen-mediated local and systemic applications of myostatin-targeting siRNA increase skeletal muscle mass.,
Gene Therapy, Vol.15, No.15, 1126-1130, 2008.
(DOI: 10.1038/gt.2008.24,   PubMed: 18323791)
67. Naozumi Ishimaru, Akiko Yamada, Masayuki Kohashi, Rieko Arakaki, Tetsuyuki Takahashi, Keisuke Izumi and Yoshio Hayashi :
Development of Inflammatory Bowel Disease in Long-Evans Cinnamon Rats Based on CD4+CD25+Foxp3+ Regulatory T Cell Dysfunction,
The Journal of Immunology, Vol.180, No.10, 6997-7008, 2008.
(PubMed: 18453622)
68. Masayuki Kohashi, Naozumi Ishimaru, Rieko Arakaki and Yoshio Hayashi :
Effective Treatment With Oral Administration of Rebamipide in a Model of Sjogren's Syndrome,
Arthritis and Rheumatism, Vol.58, No.2, 389-400, 2008.
(DOI: 10.1002/art.23163,   PubMed: 18240266)
69. Kazuhito Satomura, Reiko Tokuyama, Tetsuya Yuasa, Y Yamasaki, Seiko Tatehara, Naozumi Ishimaru, Yoshio Hayashi and Masaru Nagayama :
Possible involvement of stem cell factor and endothelin-1 in the emergence of pigmented squamous cell carcinoma in oral mucosa.,
Journal of Oral Pathology & Medicine, Vol.36, No.10, 621-624, 2007.
(DOI: 10.1111/j.1600-0714.2007.00587.x,   PubMed: 17944756)
70. Naoko Ohtani, Yuko Imamura, Kimi Yamakoshi, Fumiko Hirota, Rika Nakayama, Yoshiaki Kubo, Naozumi Ishimaru, Akiko Takahashi, Atsushi Hirao, Takatsune Shimizu, David J. Mann, Hideyuki Saya, Yoshio Hayashi, Seiji Arase, Mitsuru Matsumoto, Nakao Kazuki and Eiji Hara :
Visualizing the dynamics of p21 (Wafl/Cip1)cyclin-dependent kinase inhibitor expression in living animals.,
Proceedings of the National Academy of Sciences of the United States of America, Vol.104, No.38, 15034-15039, 2007.
(DOI: 10.1073/pnas.0706949104,   PubMed: 17848507)
71. Takashi Izawa, Naozumi Ishimaru, Keiji Moriyama, Masayuki Kohashi, Rieko Arakaki and Yoshio Hayashi :
Crosstalk between RANKL and Fas signaling in dendritic cells controls immune tolerance,
Blood, Vol.110, No.1, 242-250, 2007.
(DOI: 10.1182/blood-2006-11-059980,   PubMed: 17371940)
72. Naozumi Ishimaru, Hidehiro Kishimoto, Yoshio Hayashi and Jonathan Sprent :
Regulation of naive T cell function by the NF-κB2 pathway,
Nature Immunology, Vol.7, No.7, 763-772, 2006.
(DOI: 10.1038/ni1351,   PubMed: 16732290)
73. Nobuhiko Katunuma, Quang Trong Le, Etsuko Murata, Atsushi Matsui, Eiji Majima, Naozumi Ishimaru, Yoshio Hayashi and Atsushi Ohashi :
A novel apoptosis cascade mediated by lysosomal lactoferrin and its participation in hepatocyte apoptosis induced by D-galactosamine.,
FEBS Letters, Vol.580, No.15, 3699-3705, 2006.
(DOI: 10.1016/j.febslet.2006.05.057,   PubMed: 16765951)
74. Masayuki Azuma, Yuki Ashida, Tetsuya Tamatani, Katsumi Motegi, Natsumi Takamaru, Naozumi Ishimaru, Yoshio Hayashi and Mitsunobu Sato :
Cepharanthin,a biscoclaurine alkaloid,prevents destruction of acinar tissues in murine Sjogren's syndrome.,
The Journal of Rheumatology, Vol.33, No.5, 912-920, 2006.
(PubMed: 16652422)
75. Naoto Suzue, Takeshi Nikawa, Yuko Onishi, Chiharu Yamada, Katsuya Hirasaka, Takayuki Ogawa, Harumi Furochi, Hirofumi Kosaka, Kazumi Ishidoh, Gu Hua, Shin'ichi Takeda, Naozumi Ishimaru, Yoshio Hayashi, Hironori Yamamoto, Kyoichi Kishi and Natsuo Yasui :
Ubiqitin Ligase Cbl-b Downregulates Bone Formation Through Suppression of IGF-I Signaling in Osteoblasts During Denervation,
Journal of Bone and Mineral Research, Vol.21, No.5, 722-734, 2006.
(DOI: 10.1359/jbmr.060207,   PubMed: 16734387,   Elsevier: Scopus)
76. Naozumi Ishimaru, Rieko Arakaki, Fumie Omotehara, Kouichi Yamada, Kenji Mishima, Ichiro Saito and Yoshio Hayashi :
Novel role for RbAp48 in tissue-specific,estrogen deficiency-dependent apoptosis in the exocrine glands.,
Molecular and Cellular Biology, Vol.26, No.8, 2924-2935, 2006.
(DOI: 10.1128/MCB.26.8.2924-2935.2006,   PubMed: 16581768)
77. Naozumi Ishimaru and Yoshio Hayashi :
Crucial Roles of NF-kB for T Cell Activation,
Journal of Oral Biosciences, Vol.48, No.1, 12-17, 2006.
(DOI: 10.2330/joralbiosci.48.12,   CiNii: 10017280299)
78. Nobuhiko Katumuma, Atsushi Ohashi, Etsuko Sano, Naozumi Ishimaru, Yoshio Hayashi and Etsuko Murata :
Catechin derivatives:specific inhibitor for caspases-3,7and 2,and the prevention of apoptosis at the cell and animal levels.,
FEBS Letters, Vol.580, No.3, 741-746, 2006.
(DOI: 10.1016/j.febslet.2005.12.087,   PubMed: 16413020)
79. Katsushi Miyazaki, Noriaki Takeda, Naozumi Ishimaru, Fumie Omotehara, Rieko Arakaki and Yoshio Hayashi :
Analysis of in vivo role of alpha-fodrin autoantigen in primary Sjogren's syndrome,
The American Journal of Pathology, Vol.167, No.4, 1051-1059, 2005.
(DOI: 10.1016/S0002-9440(10)61194-7,   PubMed: 16192640)
80. Noriyuki Kuroda, Tasuku Mitani, Naoki Takeda, Naozumi Ishimaru, Rieko Arakaki, Yoshio Hayashi, Yoshimi Bando, Keisuke Izumi, Takeshi Takahashi, Takashi Nomura, Shimon Sakaguchi, Tomoo Ueno, Yousuke Takahama, Daisuke Uchida, Shijie Sun, Fumiko Kajiura, Yasuhiro Mouri, Hongwei Han, Akemi Matsushima, Gen Yamada and Mitsuru Matsumoto :
Development of autoimmunity against transcriptionally unrepressed target antigen in the thymus of Aire-deficient mice,
The Journal of Immunology, Vol.174, No.4, 1862-1870, 2005.
(DOI: 10.3410/f.1024264.287833,   PubMed: 15699112)
81. Masaru Kobayashi, Natsuo Yasui, Naozumi Ishimaru, Rieko Arakaki and Yoshio Hayashi :
Development of Autoimmune Arthritis With Aging Via Bystander T Cell Activation in the Mouse Model of Sjogren's Syndrome,
Arthritis and Rheumatism, Vol.50, No.12, 3974-3984, 2004.
(DOI: 10.1002/art.20679,   PubMed: 15593201)
82. Yuki Hayashi, Naozumi Ishimaru, Rieko Arakaki, Shin-ichi Tsukumo, Hitomi Fukui, Kenji Kishihara, Hiroshi Shiota, Koji Yasutomo and Yoshio Hayashi :
Effective Treatment of a Mouse Model of Sjogren's Syndrome With Eyedrop Administrasiton of Anti-CD4 Monoclonal Antibody,
Arthritis and Rheumatism, Vol.50, No.9, 2903-2910, 2004.
(DOI: 10.1002/art.20472,   PubMed: 15457459)
83. Tomoko Yoneda, Naozumi Ishimaru, Rieko Arakaki, Masaru Kobayashi, Takashi Izawa, Keiji Moriyama and Yoshio Hayashi :
Estrogen deficiency accelerates murine autoimmune arthritis associated with receptor activator of nuclear factor-kappaB ligand-mediated osteoclastogenesis,
Endocrinology, Vol.145, No.5, 2384-2391, 2004.
(DOI: 10.1210/en.2003-1536,   PubMed: 14726437)
84. Hideko Endo, Mitsuyoshi Hirokawa, Naozumi Ishimaru, Yasushi Tanaka, Michiko Yamashita, Mika Sakaki, Yoshio Hayashi and Toshiaki Sano :
Unique cell membrane expression if topoisomerase-ll alpha as a useful diagnostic marker of liposarcoma,
Pathology International, Vol.54, No.3, 145-150, 2004.
(DOI: 10.1111/j.1440-1827.2003.01600.x,   PubMed: 14989736)
85. Naozumi Ishimaru, Rieko Arakaki, Nobuhiko Katunuma and Yoshio Hayashi :
Critical Role of Cathepsin-Inhibitors for Autoantigen Processing and Autoimmunity,
Advances in Enzyme Regulation, Vol.44, No.1, 309-320, 2004.
(DOI: 10.1016/j.advenzreg.2003.11.004,   PubMed: 15581498)
86. Rieko Arakaki, Naozumi Ishimaru, Ichiro Saito, Masaru Kobayashi, Natsuo Yasui, Takayuki Sumida and Yoshio Hayashi :
Development of Autoimmune Exocrinopathy Resembling Sjogren's Syndrome in Adoptively Transferred Mice With Autoreactive CD4+ T Cells,
Arthritis and Rheumatism, Vol.48, No.12, 3603-3609, 2003.
(DOI: 10.1002/art.11352,   PubMed: 14674013)
87. Kouichi Ogawa, Shinji Nagahiro, Rieko Arakaki, Naozumi Ishimaru, Masaru Kobayashi and Yoshio Hayashi :
Anti-a-fodrin autoantibodies in Moyamoya disease,
Stroke, Vol.34, No.12, 244-246, 2003.
(DOI: 10.1161/01.STR.0000100479.63243.48,   PubMed: 14657555)
88. Naozumi Ishimaru, Rieko Arakaki, Megumi Watanabe, Kobayashi Masaru, Katsushi Miyazaki and Yoshio Hayashi :
Development of autoimmune exocrinopathy resembling Sjogren's syndorome in estorogen deficient mice of healthy background,
The American Journal of Pathology, Vol.163, No.4, 1481-1490, 2003.
(DOI: 10.1016/S0002-9440(10)63505-5,   PubMed: 14507655)
89. Kaoru Saegusa, Naozumi Ishimaru, Kumiko Yanagi, Rieko Arakaki, Kouichi Ogawa, Ichiro Saito, Nobuhiko Katunuma and Yoshio Hayashi :
Cathepsin S-inhibitor prevents autoantigen presentation and autoimmunity,
The Journal of Clinical Investigation, Vol.110, No.3, 361-369, 2002.
(DOI: 10.1172/JCI14682,   PubMed: 12163455)
90. Kaoru Saegusa, Naozumi Ishimaru, Kumiko Yanagi, Kenji Mishima, Rieko Arakaki, Takashi Suda, Ichiro Saito and Yoshio Hayashi :
Prevention and induction of autoimmune exocrinopathy is dependent on pathogenic autoantigen cleavage in murine Sjogren's syndrome,
The Journal of Immunology, Vol.169, No.2, 1050-1057, 2002.
(PubMed: 12097413,   CiNii: 80015444001)
91. Yoshiko Noda, Yukihiro Momota, Kazuhito Satomura, Nobuyuki Kamata, Naozumi Ishimaru and Masaru Nagayama :
A case of aspergillosis of the maxillary sinus: discussion of the usefulness of serological examinations,
Japanese Journal of Oral & Maxillofacial Surgery, Vol.47, No.12, 811-814, 2001.
(DOI: 10.5794/jjoms.47.811,   CiNii: 10009461374)
92. Naozumi Ishimaru, Kumiko Yanagi, Kouichi Ogawa, Takashi Suda, Ichiro Saito and Yoshio Hayashi :
Possible Role of Organ-Specific Autoantigen for Fas Ligand-Mediated Activation-Induced Cell Death in Murine Sjögren's Syndrome1,
The Journal of Immunology, Vol.167, No.10, 6031-6037, 2001.
(DOI: 10.4049/jimmunol.167.10.6031,   PubMed: 11698484,   Elsevier: Scopus)
93. Kaoru Saegusa, Naozumi Ishimaru, Norio Haneji, Kumiko Yanagi, Tomoko Yoneda, Ichiro Saito and Yoshio Hayashi :
Mechanisms of neonatal tolerance induced in an animal model for primary Sjogren's syndrome by intravenous administration of autoantigen,
Scandinavian Journal of Immunology, Vol.52, No.3, 264-270, 2000.
(DOI: 10.1046/j.1365-3083.2000.00777.x,   PubMed: 10972902,   Elsevier: Scopus)
94. Kaoru Saegusa, Naozumi Ishimaru, Kumiko Yanagi, Norio Haneji, Mizuho Nishino, Masayuki Azuma, Ichiro Saito and Yoshio Hayashi :
Autoantigen-specific CD4+CD28low T cell subset prevents autoimmune exocrinopathy in murine Sjogren's syndrome,
The Journal of Immunology, Vol.165, No.4, 2251-2257, 2000.
(DOI: 10.4049/jimmunol.165.4.2251,   PubMed: 10925313,   Elsevier: Scopus)
95. Keiko Aota, Masayuki Azuma, Tsuyoshi Yamashita, Testuya Tamatani, Katsumi Motegi, Naozumi Ishimaru, Yoshio Hayashi and Mitsunobu Sato :
5-Fluorouracil Induces Apoptosis through the Suppression of NF-κB Activity in Human Salivary Gland Cancer Cells,
Biochemical and Biophysical Research Communications, Vol.273, No.3, 1168-1174, 2000.
(DOI: 10.1006/bbrc.2000.3072,   PubMed: 10891390)
96. Naozumi Ishimaru, Tomoko Yoneda, Kaoru Saegusa, Kumiko Yanagi, Norio Haneji, Keiji Moriyama, Ichiro Saito and Yoshio Hayashi :
Severe destructive autoimmune lesions with aging in murine Sjogren's syndrome through Fas-mediated apoptosis,
The American Journal of Pathology, Vol.156, No.5, 1557-1564, 2000.
(DOI: 10.1016/S0002-9440(10)65027-4,   PubMed: 10793067,   Elsevier: Scopus)
97. Kaoru Saegusa, Naozumi Ishimaru, Kumiko Yanagi, Norio Haneji, Mizuho Nishino, Masayuki Azuma and Yoshio Hayashi :
Treatment with anti-CD86 costimulatory molecule prevents the autoimmune lesions in murine Sjogren's syndrome (SS) through up-regulated Th2 response,
Clinical and Experimental Immunology, Vol.119, No.2, 354-360, 2000.
98. Kaoru Saegusa, Naozumi Ishimaru, Kumiko Yanagai, Norio Haneji, Mizuho Nishino, Masayuki Azuma, Ichiro Saito and Yoshio Hayashi :
Treatment with anti-CD 86 costimulatory molecule prevents the autoimmune lesions in murine Sjogren's syndrome(SS) through up-regulated Th2 response,
Clinical and Experimental Immunology, Vol.119, 354-360, 2000.
99. Naozumi Ishimaru, 羽地 則雄, 柳 久美子 and Yoshio Hayashi :
Theraputic effect of fosfomycin in animal model of sjögren's syndrome,
Japanese Journal of Chemotherapy, Vol.48, 775-779, 2000.
(DOI: 10.11250/chemotherapy1995.48.775,   Elsevier: Scopus)
100. Kouji Nitta, Eiji Hayashi, Kenji Fujisawa, Nobuyuki Kamata, Masaru Nagayama, Naozumi Ishimaru and Yoshio Hayashi :
Two cases of ameloblastic fibro-odontoma,
Japanese Journal of Oral & Maxillofacial Surgery, Vol.46, No.8, 481-483, 2000.
(DOI: 10.5794/jjoms.46.481)
101. Naozumi Ishimaru, Kaoru Saegusa, Kumiko Yanagi, Norio Haneji, Ichiro Saito and Yoshio Hayashi :
Estrogen Deficiency Accelerates Autoimmune Exocrinopathy in Murine Sjögren's Syndrome through Fas-Mediated Apoptosis,
The American Journal of Pathology, Vol.155, No.1, 173-181, 1999.
102. Naozumi Ishimaru, Kaoru Saegusa, Kumiko Yanagi, Norio Haneji, Ichiro Saito and Yoshio Hayashi :
Estrogen dediciency accelerates autoimmune exocrinopathy in murine Sjogren's syndrome through Fas-dediated apoptosis,
The American Journal of Pathology, Vol.155, No.1, 173-181, 1999.
(DOI: 10.1016/S0002-9440(10)65111-5,   PubMed: 10393849,   Elsevier: Scopus)
103. Mariko Takahashi, Naozumi Ishimaru, Kumiko Yanagi, Kaoru Saegusa, Norio Haneji, Hiroshi Shiota and Yoshio Hayashi :
Requirement for splenic CD4+ T cells in the immune privilege of the anterior chamber of the eye,
Clinical and Experimental Immunology, Vol.116, No.2, 231-237, 1999.
104. Ichiro Saito, Kumiko Haruta, Misa Shimuta, Hiroko Inoue, Hiroshi Sakurai, Koichi Yamada, Naozumi Ishimaru, Hiroyuki Higashiyama, Takayuki Sumida, Hiroshi Ishida, Takashi Suda, Tetsuo Noda, Yoshio Hayashi and Kazuo Tsubota :
Fas ligand-mediated exocrinopathy resembling Sjogren's syndrome in mice transgenic for IL-10,
The Journal of Immunology, Vol.162, No.5, 2488-2492, 1999.
(PubMed: 10072487,   Elsevier: Scopus)
105. Kazuo Tsubota, Ichiro Saito, Naozumi Ishimaru and Yoshio Hayashi :
Use of topical cyclosporin A in a primary Sjogren's syndrome mouse model,
Investigative Ophthalmology & Visual Science, Vol.39, No.9, 1551-1559, 1998.
(PubMed: 9699544)
106. Kaoru Saegusa, Naozumi Ishimaru, Kumiko Yanagi, Norio Haneji, Mizuho Nishino and Yoshio Hayashi :
Mechanisms of transfer into SCID mice reconstituted with tissue-infiltrating cells from murine model for Sjogren's syndrome,
Oral Med Pathol, Vol.3, 67-74, 1998.
107. Kumiko Yanagi, Naozumi Ishimaru, Norio Haneji, Kaoru Saegusa, Ichiro Saito and Yoshio Hayashi :
Anti-120-kDa a-fodrin immune response withTh-1-cytokine profile in the NOD mouse model of Sjogren's syndrome,
Eur. J. Immunol., Vol.28, 3336-3345, 1998.
108. Naozumi Ishimaru, Norio Haneji, Hironori Hamano, Kumiko Yanagi, Mariko Takahashi and Yoshio Hayashi :
Accelerated onset of age-related autoimmune lesions in MRL/+ mice by ovariectomy,
Mechanisms of Ageing and Development, Vol.93, No.1-3, 145-156, 1997.
109. Mariko Takahashi, Naozumi Ishimaru, Kumiko Yanagi, Norio Haneji, Ichiro Saito and Yoshio Hayashi :
High incidence of autoimmune dacryoadenitis in male non-obese diabetic (NOD) mice depending on sex steroid,
Clinical and Experimental Immunology, Vol.109, 555-561, 1997.
110. Kumiko Yanagi, Norio Haneji, Naozumi Ishimaru, Ichiro Saito and Yoshio Hayashi :
Analysis of T cell receptor Vb usage in the autoimmune sialadenitis of non-obese diabetic (NOD) mice,
Clinical and Experimental Immunology, Vol.110, 440-446, 1997.
111. Yoshio Hayashi, Norio Haneji, Hironori Hamano, Kumiko Yanagi, Mariko Takahashi and Naozumi Ishimaru :
Effector Mechanism of Experimental Autoimmune Sialadenitis in the Mouse Model for Primary Sjogren's Syndrome,
Cellular Immunology, Vol.171, No.2, 217-225, 1996.
(DOI: 10.1006/cimm.1996.0196,   PubMed: 8806790)
112. Kumiko Yanagi, Norio haneji, Naozumi Ishimaru, Hironori Hamano and Yoshio Hayashi :
Immunopathological analysis of mucosal melanocyte distribution in the human lower lip of the elderly,
Pathobiology, Vol.64, No.3, 156-160, 1996.
113. Hironori Hamano, Norio Haneji, Kumiko Yanagi, Naozumi Ishimaru and Yoshio Hayashi :
Expression of HLA-DR and cytokine genes on interferon-γ-stimulated human salivary gland cell line,
Pathobiology, Vol.64, No.5, 255-261, 1996.
(PubMed: 9068008)
114. Yoshio Hayashi, Hironori Hamano, Norio Haneji, Naozumi Ishimaru and Kumiko Yanagi :
Biased T cell receptor Vβ gene usage during specific stages of the development of autoimmune sialadenitis in the MRL/lpr mouse model of Sjogren's syndrome,
Arthritis &Rheumatism, Vol.38, No.8, 1077-1084, 1995.

Academic Paper (Unrefereed Paper):

1. Naozumi Ishimaru, 岸本 英博, Yoshio Hayashi and Sprent Jonathan :
NF-kB2によるT細胞の新たな調節機構,
実験医学 月刊, Vol.24, No.16, 2513-2516, 2006.
2. Yoshio Hayashi, Naozumi Ishimaru and Rieko Arakaki :
RbAp48遺伝子導入マウスにおけるシェーグレン症候群様病態の出現,
Clinical Immunology, Vol.45, No.5, 533-537, 2006.

Academic Letter:

1. Naozumi Ishimaru :
[Oral immune system and oral immune disorder.],
Clinical Calcium, Vol.27, No.10, 1363-1368, 2017.
(PubMed: 28947686)

Review, Commentary:

1. M Samadarani B S Siriwardena, Takaaki Tsunematsu, Guangying Qi, Naozumi Ishimaru and Yasusei Kudo :
Invasion-Related Factors as Potential Diagnostic and Therapeutic Targets in Oral Squamous Cell Carcinoma-A Review.,
International Journal of Molecular Sciences, Vol.19, No.5, May 2018.
(Tokushima University Institutional Repository: 112412,   DOI: 10.3390/ijms19051462,   PubMed: 29758011,   Elsevier: Scopus)
2. Guangying Qi, Jing Liu, Sisi Mi, Takaaki Tsunematsu, Shengjian Jin, Wenhua Shao, Tian Liu, Naozumi Ishimaru, Bo Tang and Yasusei Kudo :
Aurora Kinase Inhibitors In Head And Neck Cancer.,
Current Topics in Medicinal Chemistry, Vol.18, No.3, 199-213, Jan. 2018.
(Tokushima University Institutional Repository: 113572,   DOI: 10.2174/1568026618666180112163741,   PubMed: 29332580)
3. Masako Saito, Kunihiro Otsuka, Aya Ushio, Akiko Yamada, Rieko Arakaki, Yasusei Kudo and Naozumi Ishimaru :
Unique Phenotypes and Functions of Follicular Helper T Cell and Regulatory T Cell in Sjögren's Syndrome.,
Current Rheumatology Reviews, Vol.14, No.3, 239-245, Jan. 2017.
(DOI: 10.2174/1573397113666170125122858,   PubMed: 28124612)
4. Yasusei Kudo, Tada Hidesuke, Natsumi Fujiwara, Tada Yoshiko, Takaaki Tsunematsu, Yoichiro Miyake and Naozumi Ishimaru :
Oral environment and cancer,
Genes and Environment, Vol.38, No.13, Aug. 2016.
(DOI: 10.1186/s41021-016-0042-z,   PubMed: 27482300)
5. Akiko Yamada, Rieko Arakaki, Masako Saito, Takaaki Tsunematsu, Yasusei Kudo and Naozumi Ishimaru :
Role of regulatory T cell in the pathogenesis of inflammatory bowel disease.,
World Journal of Gastroenterology : WJG, Vol.22, No.7, 2195-2205, Feb. 2016.
(Tokushima University Institutional Repository: 110976,   DOI: 10.3748/wjg.v22.i7.2195,   PubMed: 26900284,   Elsevier: Scopus)
6. Rieko Arakaki, Akiko Yamada, Yasusei Kudo, Yoshio Hayashi and Naozumi Ishimaru :
Mechanism of Activation-Induced Cell Death of T Cells and Regulation of FasL Expression.,
Critical Reviews in Immunology, Vol.34, No.4, 301-314, May 2014.
(DOI: 10.1615/CritRevImmunol.2014009988,   PubMed: 24941158,   Elsevier: Scopus)
7. Shinji Iizuka, Naozumi Ishimaru and Yasusei Kudo :
Matrix metalloproteinases: the gene expression signatures of head and neck cancer progression.,
Cancers, Vol.6, No.1, 396-415, Feb. 2014.
(Tokushima University Institutional Repository: 113577,   DOI: 10.3390/cancers6010396,   PubMed: 24531055,   Elsevier: Scopus)
8. Akiko Yamada, Rieko Arakaki, Yasusei Kudo and Naozumi Ishimaru :
Targeting IL-1 in Sjögren's syndrome.,
Expert Opinion on Therapeutic Targets, Vol.17, No.4, 393-401, Jan. 2013.
(DOI: 10.1517/14728222.2013.754427,   PubMed: 23320392)
9. Yoshio Hayashi, Rieko Arakaki and Naozumi Ishimaru :
Sjogren's syndrome,
The Journal of the Japanese Society of Internal Medicine, Vol.100, No.5, 1262-1268, Jun. 2011.
(DOI: 10.2169/naika.100.1262,   CiNii: 10029097111,   Elsevier: Scopus)
10. Naozumi Ishimaru, Takashi Izawa and Yoshio Hayashi :
Regulation of immune response by RANKL and Fas,
Clinical Immunology & Allergology, Vol.55, No.2., 142-147, Apr. 2011.
(CiNii: 40018745171)
11. Rieko Arakaki, Naozumi Ishimaru and Yoshio Hayashi :
Immunotherapeutic targets in estrogen deficiency-dependent Sjögren's syndrome-related manifestations,
Immunotherapy, Vol.2, No.3, 339-346, May 2010.
(DOI: 10.2217/imt.10.18,   PubMed: 20635899)
12. Takashi Izawa, Naozumi Ishimaru, Eiji Tanaka and Yoshio Hayashi :
Crosstalk between RANKL and Fas signaling in dendritic cells controls immune tolerance,
Clinical Immunology & Allergology, Vol.52, No.5, 471-477, Nov. 2009.
(CiNii: 40016915514)
13. Naozumi Ishimaru, 岸本 英博, Yoshio Hayashi and Sprent Jonathan :
NF-kB2によるT細胞の新たな調節機構,
Experimental Medicine, Vol.24, No.16, 2513-2516, Jan. 2007.
14. Naozumi Ishimaru and Yoshio Hayashi :
Crucial Roles of NF-κB for T Cell Activation,
Journal of Oral Biosciences, Vol.48, No.1, 12-17, Feb. 2006.
(DOI: 10.1016/S1349-0079(06)80014-9,   Elsevier: Scopus)
15. Yoshio Hayashi, Rieko Arakaki and Naozumi Ishimaru :
エストロゲンと自己免疫疾患,
Annual Review糖尿病・代謝・内分泌2006, 241-246, Jan. 2006.
16. Yoshio Hayashi, Naozumi Ishimaru and 表原 文江 :
唾液腺の自己免疫病変,
病理と臨床, No.25, 116-121, 2005.
17. Yoshio Hayashi, Naozumi Ishimaru and Fumie Omotehara :
唾液腺の自己免疫病変,
病理と臨床, Vol.23, 116-121, 2005.
18. Yoshio Hayashi, Rieko Arakaki and Naozumi Ishimaru :
Crucial Role of Tissue-Specific Apoptosis on the Development of Primary Sjogren's Syndrome,
Oral Science International, Vol.1, No.2, 55-64, Nov. 2004.
(DOI: 10.1016/S1348-8643(04)80007-7,   CiNii: 10017396417)
19. Yoshio Hayashi, Rieko Arakaki and Naozumi Ishimaru :
Apoptosis and Estrogen Deficiency in Primary Sjögren Syndrome,
Current Opinion in Rheumatology, Vol.16, No.5, 522-526, Sep. 2004.
(DOI: 10.1097/01.bor.0000135450.78047.78,   PubMed: 15314488)
20. Yoshio Hayashi, Hitomi Fukui and Naozumi Ishimaru :
Aging and Autoimmune Diseases,
日本アフェレシス学会雑誌, Vol.23, No.2, 176-181, May 2004.
21. Yoshio Hayashi, Rieko Arakaki and Naozumi Ishimaru :
The role of caspase cascade on the development of primary Sjogren's syndrome,
The Journal of Medical Investigation : JMI, Vol.50, No.1,2, 32-38, Feb. 2003.
(Tokushima University Institutional Repository: 110675,   PubMed: 12630566)
22. Yoshio Hayashi, Rieko Arakaki and Naozumi Ishimaru :
シェーグレン症候群発症の分子機構,
Clinical Immunology, Vol.40, 196-204, 2003.
23. 渡辺 恵, 市川 哲雄, Naozumi Ishimaru, Rieko Arakaki and Yoshio Hayashi :
接触性過敏症における樹状細胞の役割,
アレルギー科, Vol.15, 481-487, 2003.
24. Naozumi Ishimaru, Rieko Arakaki and Yoshio Hayashi :
自己免疫疾患の発症とアポトーシス,
細胞, Vol.35, 20-23, 2003.
25. Yoshio Hayashi and Naozumi Ishimaru :
自己免疫疾患における分子模倣仮説,
Journal of Clinical and Experimental Medicine, Vol.206, 855-858, 2003.
26. Yoshio Hayashi, Rieko Arakaki and Naozumi Ishimaru :
シェ-グレン症候群発症の分子機構,
Clinical Immunology, Vol.40, 196-204, 2003.
27. Yoshio Hayashi, 柳 久美子 and Naozumi Ishimaru :
免疫異常からみたリウマチ性疾患の臓器病変:口腔内病変,
リウマチ科, Vol.21, 630-638, 1999.

Proceeding of International Conference:

1. Takaaki Tsunematsu, Naozumi Ishimaru and Yasusei Kudo :
APC/CCdh1-mediated degradation of Borealin triggers differentiation of pluripotent stem cells.,
FASEB meeting Ubiquitin and Cellular Regulation, Snowmass Village, CO, USA, May 2018.
2. Kunihiro Ohtsuka, Akiko Yamada, Masako Saito, Aya Ushio, Takaaki Tsunematsu, Rieko Arakaki, Yasusei Kudo, Hidehiro Kishimmoto and Naozumi Ishimaru :
Analysis of follicular helper T cells in a mouse model for Sjogren's Syndorome.,
11th International Congress of Autoimmunity, Lisbon, May 2018.
3. Aya Ushio, Rieko Arakaki, Kunihiro Ohtsuka, Yasusei Kudo and Naozumi Ishimaru :
CCL22Producing Resident Macrophages Enhances InflaMMation in Salivary Glands of Sjogren's Syndorome.,
11th International Congress of Autoimmunity, Lisbon, May 2018.
4. Rieko Arakaki, Aya Ushio, Kunihiro Ohtsuka, Yasusei Kudo and Naozumi Ishimaru :
NF-kB2 Controls the Migratory of Memory T cells to the Target Tissues in a Mouse Model of Sjogren's Syndorome by Regulating Expression of CXCR4.,
11th International Congress of Autoimmunity, Lisbon, May 2018.
5. Junhel Dalanon, S Afroz, Takuma Iwasa, Rieko Arakaki, Masamitsu Oshima, Naozumi Ishimaru and Yoshizo Matsuka :
Cytokine involvement in orofacial neuralgia: fundamental research,
Asia Pacific Dental Congress, Manila, May 2018.
6. Takashi Izawa, Rieko Arakaki and Naozumi Ishimaru :
Signal crosstalk between cytokine RANKL and AhR signaling in osteoclasts controls bone homeostasis,
The Journal of Immunology, Vol.Supplement, No.43.15, 25, Austin, May 2018.
7. Naozumi Ishimaru, Mie Kurosawa, Rieko Arakaki, Aya Ushio, otsuka kunihiro and Yasusei Kudo :
Contributions of CXCL12 and its receptor to the T cell autoimmune response in a Sjögren's syndrome murine model.,
14th International Symposium on Sjögren's Syndrome, Washington, D.C., Apr. 2018.
8. Takashi Izawa, Rieko Arakaki, Eiji Tanaka and Naozumi Ishimaru :
Crosstalk between cytokine RANKL and AhR signaling in osteoclasts controls bone homeostasis,
Gordon Research Conference; "Bones and Teeth" From Skeletal and Dental Stem Cells to Rare Bone Disease and Integrative Physiology, Houston, Jan. 2018.
9. Iwasa Takuma, Rieko Arakaki, Oshima Masamitsu, S Afroz, Miho Inoue, Goto Nami, Naozumi Ishimaru and Yoshizo Matsuka :
Up-regulation of inflammatory cytokines in trigeminal ganglia after infraorbital nerve constriction,
The Journal of Neuroscience, Washington DC, Nov. 2017.
10. Takashi Izawa, Eiji Tanaka and Naozumi Ishimaru :
The nuclear receptor AhR controls bone homeostasis by regulating osteoclast differentiation via the RANK/c-Fos signaling axis,
ASBMR 2017 Annual Meeting, Denver, Sep. 2017.
11. Takaaki Tsunematsu, Naozumi Ishimaru and Yasusei Kudo :
Chromosome passenger complex protein,Borealin is regulated by APC/C Cdh1 ubiquitin ligase complex,
Cold Spring Harbor Laboratory Meeting:The Ubiquitin Family, New York, Apr. 2017.
12. Takaaki Tsunematsu, Naozumi Ishimaru and Yasusei Kudo :
The APC/C-Cdh1-Borealin axis has critical role in the maintenance of undifferentiated state in embryonal carcinoma cells,
8th International Conference SUMO, Ubiquitin, UBL Proteins- Implications for Human Diseases, Shanghai, Oct. 2016.
13. Akiko Yamada, Aya Ushio, Rieko Arakaki, Yasusei Kudo and Naozumi Ishimaru :
Impaired Expansion of Regulatory T cells in a Neonatal Thymectomy-induced Autoimmune Mouse Model,
ICI2016, Melbourne, Aug. 2016.
14. Masako Saito, Kunihiro Ohtsuka, Aya Ushio, Mie Kurosawa, Akiko Yamada, Yasusei Kudo, Rieko Arakaki and Naozumi Ishimaru :
Abnormal germinal center(GC)reaction in autoimmunity.,
ICI2016, Melbourne, Aug. 2016.
15. Yasusei Kudo, Takaaki Tsunematsu and Naozumi Ishimaru :
Chromosome passenger complex protein,Borealin is regulated by APC/C-Cdh1 ubiquitin ligase complex,
FASEB Ubiquitin & Cellular Regulation, Montana, Jun. 2016.
16. Yasusei Kudo, 常松 貴明 and Naozumi Ishimaru :
Aurora-A controls pre-replicative complex formation and DNA replication by promoting the stabilization of geminin and CDT1 in mitosis.,
7th International Conference SUMO,Ubiquitin,UBL Proteins:Implications for Human Diseases, Shanghai, May 2014.
17. Yasusei Kudo, 常松 貴明 and Naozumi Ishimaru :
Geminin regulates pre-replicative complex formation though the stabilization of CDT1 in mitosis.,
American Association for Cancer Reseach, San Diego, Apr. 2014.
18. Akihiko Iwasa, Rieko Arakaki, Akiko Yamada, Eiji Tanaka, Yasusei Kudo and Naozumi Ishimaru :
Pathologenesis of Sjogren's syndrome through Aromatase and adipose tissue.,
International Congress on Autoimmunity, Niece, Mar. 2014.
19. Tomoyuki Kondo, Akiko Yamada, Rieko Arakaki, Takaaki Tsunematu, Yasusei Kudo and Naozumi Ishimaru :
Analysis of the regulatory mechanism for tumor immunity by using autoimmune lpr mice.,
International Congress on Autoimmunity, Niece, Mar. 2014.
20. Koichi Yamada, Akihiko Iwasa, Tomoyuki Kondo, Mie Kurosawa, Rieko Arakaki, Akiko Yamada, Yasusei Kudo, Y Taquahashi, A Takagi, J Kanno and Naozumi Ishimaru :
Invivo effect of multi-wall carbon nanotubes on immune system.,
6th International Symposium on Nanotechnology,Occupational and Environmental system., Nagoya, Nov. 2013.
21. Akiko Yamada, Rieko Arakaki, Mie Kurosawa, Tomoyuki Kondo, Koichi Yamada, Yoshio Hayashi and Naozumi Ishimaru :
Deficient differentiation of Treg cell in a murine model of Sjogren's syndrome.,
15th International Congress of Immunology, Milan, Aug. 2013.
22. Yosuke Shikama, Naozumi Ishimaru, Yasusei Kudo, Yukiko Bandou, Nanako Aki, Yoshio Hayashi and Makoto Funaki :
High Levels of Free Fatty Acids May Advance the Severity of Primary Sjögrens Syndrome,
Diabetes, Vol.62, No.Supplement 1, A166, Jul. 2013.
23. Masahiro Hiasa, Masahiro Abe, Rieko Arakaki, Akiko Yamada, Kenzo Asaoka, Toshio Matsumoto, Yoshio Hayashi and Naozumi Ishimaru :
RelB attenuates the activation of the classical NF-κB pathway to facilitate osteoblastogenesis,
ANZBMS Annual Scientific Meeting, Perth, Sep. 2012.
24. Ritsuko 徳永 律子 Oura, Akiko Yamada, Rieko Arakaki, Naozumi Ishimaru and Yoshio Hayashi :
Pathological Analysis of Autoimmunity in NF-B1KO/LPR mice.,
8th International Congress on Autoimmunity, Granada, May 2012.
25. Akiko Yamada, Naozumi Ishimaru, Rieko Arakaki and Yoshio Hayashi :
Cathepsin L inhibition prevents murine autoimmune diabetes via suppression of CD8+T cell activity.,
8th International Congress on Autoimmunity, Granada, May 2012.
26. Kazuma Matsumoto, Naozumi Ishimaru, Takashi Izawa, Masahiro Hiasa, Yoshio Hayashi and Eiji Tanaka :
Hyperfunctions of osteoclasts in a rheumatoid arthritis model,
ASBMR 2011 Annual Meeting, San Diego, Sep. 2011.
27. Kazuma Matsumoto, Naozumi Ishimaru, Yoshio Hayashi and Eiji Tanaka :
Analysis of osteoclast activation in the pathogenesis of rheumatoid arthritis,
International Joint Symposium: The University of Tokushima, Universitas Gadjah Mada, Niigata University, Denpasar, Bali, Dec. 2010.
28. Ashrin Nur Meinar, Naozumi Ishimaru, Megumi Watanabe, Yoshio Hayashi and Tetsuo Ichikawa :
Analysis of Molecular Mechanism for Pathogenesis of Metal Allergy,
International Joint Symposium, The University of Tokushima-Niigata University-Gajah Mada University, Bali, Dec. 2010.
29. Naozumi Ishimaru, Akiko Yamada, Rieko Arakaki, Yousuke Takahama and Yoshio Hayashi :
Critical Signaling Pathway via CCR7 of Foxp3+CD25+CD4+ Regulatory T Cells for the Egress from Lymph Nodes,
international immunology, Aug. 2010.
30. Kazuma Matsumoto, Naozumi Ishimaru, Takashi Izawa, Rieko Arakaki, Ritsuko 徳永 律子 Oura, Eiji Tanaka and Yoshio Hayashi :
Fas-independent apoptosis of T cells via DCs controls autoimmune arthritis,
international immunology, Vol.22, No.1, 113, Aug. 2010.
31. Ritsuko 徳永 律子 Oura, Naozumi Ishimaru, Rieko Arakaki, Takashi Izawa, Akiko Yamada, Kazuma Matsumoto, Eiji Tanaka and Yoshio Hayashi :
Rapid T cell death via interaction with CD11b+ macrophages in Fas-deficient host,
international immunology, Vol.22, No.1, 116, Aug. 2010.
32. Naozumi Ishimaru, Akiko Yamada, Rieko Arakaki, Yousuke Takahama and Yoshio Hayashi :
Critical signaling pathway via CCR7 of Foxp3+CD25+CD4+ regulatory T cells for the egress from lymph nodes.,
第14回国際免疫学会, Kobe, Aug. 2010.
33. Ritsuko 徳永 律子 Oura, Naozumi Ishimaru, Eiji Tanaka and Yoshio Hayashi :
Rapid peripheral T cell death in Fas-deficient mice,
88th IADR, Barcelona, Jul. 2010.
34. Nao Kinouchi, Emi Kawakami, Yutaka Ohsawa, Naozumi Ishimaru, Hideyo Ohuchi, Yoshihide Sunada, Yoshio Hayashi, Eiji Tanaka and Sumihare Noji :
Atelocollagen-mediated Systemic Administration of Myostatin siRNA Improves Muscular Dystrophy,
88th IADR, Barcelona, Jul. 2010.
35. Emi Kawakami, Nao Kinouchi, Adachi Taro, Yutaka Ohsawa, Naozumi Ishimaru, Hideyo Ohuchi, Yoshihide Sunada, Yoshio Hayashi, Eiji Tanaka and Sumihare Noji :
Special Processed Collagen-mediated Application of Myostatin-siRNA for Muscular Atrophy Diseases,
88th IADR, Barcelona, Jul. 2010.
36. Emi Kawakami, Nao Kinouchi, Yutaka Osawa, Naozumi Ishimaru, Hideyo Ohuchi, Yoshihide Sunada, Yoshio Hayashi, Eiji Tanaka and Sumihare Noji :
Strategic study of atelocollagen-mediated application of mystatin-targeting siRNA for therapeutic use for muscular atrophy diseases,
QOL International Congress, Niigata, Feb. 2010.
37. Takeo Iwata, Masamichi Kuwajima, Akiko Sukeno, Naozumi Ishimaru, Yoshio Hayashi, M Wabitsch, Noriko Mizusawa, Mitsuo Itakura and Katsuhiko Yoshimoto :
YKL-40 secreted from macrophages infiltrating into adipose tissue inhibits degradation of type I collagen.,
International symposium on diabetes, Tokyo, Mar. 2009.
38. Takashi Sakai, Li Liu, Xichuan Teng, Naozumi Ishimaru, Rika Sakai, HoangNam Tran, Nobuya Sano, Yoshio Hayashi, Ryuji Kaji and Kiyoshi Fukui :
Inflammatory disease and cancer with a decrease in Kupffer cell numbers in Nucling-konckout mouse,
20th FAOBMB Taipei Conference, Taipei, Oct. 2008.
39. Nao Kinouchi, Yutaka Osawa, Naozumi Ishimaru, Yoshio Hayashi, Keiji Moriyama, Sumihare Noji and Eiji Tanaka :
Atelocollagen-mediated lapplications of myostatin-targeting siRNA increase skeletal muscle mass,
86th IADR, Toronto, Jul. 2008.
40. Yoshio Hayashi and Naozumi Ishimaru :
Development of autoimmune expcrinopathy resembling Sjogren's syndrome in RbAp48 transgenic mice.,
Boston, Nov. 2007.
41. Takashi Izawa, Naozumi Ishimaru, Keiji Moriyama and Yoshio Hayashi :
Immunoregulatory Role of RANKL-stimulated Dendritic Cells on Autoimmune Arthritis in MRL/lpr Mice,
ACR/ARHP 71th Annual Scientific Meeting, Vol.56, No.Suppl 9, S-105, Boston, Nov. 2007.
42. Yoshio Hayashi and Naozumi Ishimaru :
Developmant of autoimmune excrinopathy resembling Sjorgen`s syndrome in RbAp48 transgenic mice.,
The 71st Annual meeting of the American College of Rheumatology., Bostone,USA., Nov. 2007.
43. Takashi Izawa, Naozumi Ishimaru, Keiji Moriyama and Yoshio Hayashi :
Immunoregulatory role of RANKL-stimulated dendritic cells on autoimmune arthritis in MRL/lpr mice,
29th Annual Meeting of the American Society for Bone and Mineral Research, Vol.22, No.SUPPL 1, S270, Honolulu, Sep. 2007.
44. Jun Ooshima, Takashi Izawa, Naozumi Ishimaru, Yoshio Hayashi and Keiji Moriyama :
Immunoregulatory Effects of Dendritic Cells Stimulated with RANKL on the Development of Autoimmune Disease in Arthritis Model Mice,
The 1st International Symposium and Workshop "The Future Direction of Oral Sciences in the 21st Century", 55, Awaji, Mar. 2007.
45. Naozumi Ishimaru :
A novel role of RbAp48 for tissue-specific apoptosis in the salivary glands depending on estrogen deficiency,
第3回ニールスステンセン記念国際唾液腺シンポジウム, Oct. 2006.
46. Hidehiro Kishimoto, Naozumi Ishimaru and Jonathan Sprent :
Regulation of NF-κB1/RelA activation by NF-κB2 in CD4+T cells.,
The American Association of Immunologist Annual Meeting, Boston, May 2006.
47. Sprenr Jonathan, Boyman Onur, Cho Hoe Jea, Naozumi Ishimaru and Kovar M :
T-Cell Specificity and the Thymus,
Scientific Report 2005, Vol.31, 105-107, La Jolla, Jan. 2006.
48. Yoshio Hayashi and Naozumi Ishimaru :
Involvement of Interstitial Pneumonia in Sjogren's Syndrome Mouse Model with Aging.,
International Symposium on T Cells in Aging., Stuttgart, Dec. 2005.
49. Yoshio Hayashi, Rieko Arakaki and Naozumi Ishimaru :
Possible Mechanism of Autoimmune Exocrinopathy Resembling Sjogren's Syndrome through RbAp48 Overexpression.,
Gordon Research Conference., Ventura, Feb. 2005.

Proceeding of Domestic Conference:

1. 山崎 泰文, Tetsuya Yuasa, Kazuhito Satomura, Naozumi Ishimaru, Yoshio Hayashi and Masaru Nagayama :
舌背部にみられた骨性分離腫の1例,
第53回日本口腔科学会中国・四国地方部会,
2. Keiko Kudoh, Kazuhito Satomura, 山崎 泰文, Masaaki Takechi, Naozumi Ishimaru, Yoshio Hayashi and Masaru Nagayama :
膿原性肉芽腫(pyogenic granuloma)の混在を認めた舌扁平上皮癌の1例,
第35回 日本口腔外科学会・中四国地方会,
3. Kumiko Kamada, Naito Kurio, Go Ohe, Keiko Kudoh, Yoshiko Yamamura, Naoyuki Fukuda, Takamitsu Mano, Yasusei Kudo, Naozumi Ishimaru and Youji Miyamoto :
上顎歯肉に発生したMicorocystic adnexal carcinoma(MAC)の1例,
第64回日本口腔外科学会総会・学術大会, Oct. 2019.
4. Naito Kurio, Kumiko Kamada, Go Ohe, 横田 美保, Yoshiko Yamamura, Yasusei Kudo, Naozumi Ishimaru and Youji Miyamoto :
上顎歯肉に発生したMicorocystic adnexal carcinoma(MAC)の1例,
第64回日本口腔外科学会総会・学術大会, Oct. 2019.
5. Naito Kurio, 鎌田 久美子, Go Ohe, 横田 美保, Yoshiko Yamamura, Keiko Kudoh, Yasusei Kudo, Takamitsu Mano, Naozumi Ishimaru and Youji Miyamoto :
歯肉腫瘤により白血病化が明らかとなった骨髄異形成症候群の1例,
第67回 日本口腔科学会中国・四国地方部会, Oct. 2019.
6. 鎌田 久美子, Naito Kurio, Go Ohe, Yoshiko Yamamura, Keiko Kudoh, Yasusei Kudo, Naozumi Ishimaru and Youji Miyamoto :
口底に発生した類基底扁平上皮癌の1例,
第18回中四国口腔癌研究会, Oct. 2019.
7. Keiko Aota, Tomoko Yamanoi, Kohichi Kani, Naozumi Ishimaru and Masayuki Azuma :
シェーグレン症候群の病態形成におけるCXCL10-CXCR3の役割,
第28回日本シェーグレン症候群学会, Sep. 2019.
8. Aya Ushio, Rieko Arakaki, Akiko Yamada, Yasusei Kudo and Naozumi Ishimaru :
The new therapeutic strategy targeting chemokine in Sjogren's Syndorome.,
日本RNAi研究会, Aug. 2019.
9. Takaaki Tsunematsu, Naozumi Ishimaru and Yasusei Kudo :
The maintenance of pluripotency by chromosome passenger complex in pluripotent stem cells.,
日本RNAi研究会, Aug. 2019.
10. Takaaki Tsunematsu, Naozumi Ishimaru and Yasusei Kudo :
染色体パッセンジャー複合体による未分化能維持機構,
第135回日本薬理学会近畿部会, Jun. 2019.
11. Tomoko Yamanoi, Keiko Aota, Hideyuki Takano, Kohichi Kani, Yukihiro Momota, Fumihiro Matsumoto, Naozumi Ishimaru and Masayuki Azuma :
舌下-オトガイ下型類皮嚢胞の一例,
第48回日本口腔外科学会中四国支部学術集会, May 2019.
12. Haruna Matsukura, Aya Ushio, Rieko Arakaki, Yasusei Kudo and Naozumi Ishimaru :
シェーグレン症候群疾患モデルにおける胚病変の解析,
第108回日本病理学会総会, May 2019.
13. Aya Ushio, Rieko Arakaki, Yasusei Kudo and Naozumi Ishimaru :
シェーグレン症候群病態形成におけるCCL22産生マクロファージの役割,
第108回日本病理学会総会, May 2019.
14. Keiko Aota, Tomoko Yamanoi, Kohichi Kani, Naozumi Ishimaru and Masayuki Azuma :
シェーグレン症候群の病態形成におけるCXCL10-CXCR3の役割,
第73回日本口腔科学会学術集会, Apr. 2019.
15. Takaaki Tsunematsu, 河合 秀彦, Naozumi Ishimaru, Pagano C. Earnshaw Michele William and Yasusei Kudo :
染色体パッセンジャー複合体による多能性幹細胞の未分化能維持機構.,
第36回染色体ワークショップ, Jan. 2019.
16. Rieko Arakaki, Nakayama Shinichiro, Aya Ushio, Otsuka Kunihiro, Kisoda Satoshi, Takaaki Tsunematsu, Akiko Yamada, Yasusei Kudo and Naozumi Ishimaru :
The role of the cleaved from IL-33 in pathogenesis of Sjogren's syndorome(SS),
Proceedings of the Japanese Society for Immunology, Dec. 2018.
17. Aya Ushio, Rieko Arakaki, Kunihiro Ohtsuka, Akiko Yamada, Yasusei Kudo and Naozumi Ishimaru :
CCL22-producing macrophages promote T cell autoimmunity in the target organ of Sjogren's syndorome.,
Proceedings of the Japanese Society for Immunology, Dec. 2018.
18. Kunihiro Ohtsuka, Akiko Yamada, Masako Saito, Aya Ushio, Satoru Kisoda, Takaaki Tsunematsu, Yasusei Kudo, Rieko Arakaki and Naozumi Ishimaru :
A crucial role of follicular helper T cells in autoimmunity of a mouse model for Sjogren's syndorome.,
Proceedings of the Japanese Society for Immunology, Dec. 2018.
19. Takaaki Tsunematsu, Naozumi Ishimaru and Yasusei Kudo :
多能性幹細胞においてAPC/CCdh1によるBorealinの分解は分化を誘発する,
第41回日本分子生物学会年会, Nov. 2018.
20. 榊原 健人, Takayuki Nakagawa, Naoyuki Fukuda, Naito Kurio, Tetsuya Tamatani, Takamitsu Mano, 大塚 邦紘, Yasusei Kudo, Naozumi Ishimaru and Youji Miyamoto :
下顎骨に発生した腺性歯原性嚢胞の1例,
第66回日本口腔科学会中国・四国地方部会, Nov. 2018.
21. Kunihiro Ohtsuka, Akiko Yamada, Masako Saito, Aya Ushio, Satoru Kisoda, Takaaki Tsunematsu, Yasusei Kudo, Rieko Arakaki and Naozumi Ishimaru :
シェーグレン症候群疾患モデルの自己免疫病変における濾胞ヘルパーT細胞の役割,
日本シェーグレン症候群学会, Sep. 2018.
22. Aya Ushio, Rieko Arakaki, Kunihiro Ohtsuka, Yasusei Kudo and Naozumi Ishimaru :
CCL22産生唾液腺マクロファージはシェーグレン症候群の病態に関与する,
シェーグレン症候群学会, Sep. 2018.
23. Kouji Hirao, Hiromichi Yumoto, Kunihiro Otsuka, Naozumi Ishimaru and Takashi Matsuo :
歯内由来病変と混同しやすい根尖病変様のエックス線透過像を有する症例,
第18回西日本歯内療法学会会研修会(2018年度), Sep. 2018.
24. Kunihiro Ohtsuka, Akiko Yamada, Masako Saito, Aya Ushio, Satoru Kisoda, Takaaki Tsunematsu, Yasusei Kudo, Rieko Arakaki and Naozumi Ishimaru :
シェーグレン症候群疾患モデルの自己免疫病変における濾胞ヘルパーT細胞の役割,
Japanese Journal of Oral Biology, Sep. 2018.
25. Kunihiro Ohtsuka, Akiko Yamada, Masako Saito, Aya Ushio, Satoru Kisoda, Takaaki Tsunematsu, Yasusei Kudo, Rieko Arakaki and Naozumi Ishimaru :
Asc/2を介した濾胞ヘルパーT細胞分化異常が自己免疫疾患の病態形成に関与する.,
日本臨床口腔病理学会, Aug. 2018.
26. Kunihiro Ohtsuka, Akiko Yamada, Masako Saito, Aya Ushio, Satoru Kisoda, Takaaki Tsunematsu, Yasusei Kudo, Rieko Arakaki and Naozumi Ishimaru :
シェーグレン症候群疾患モデルの自己免疫病変における濾胞ヘルパーT細胞の役割,
分子病理学研究会, Jul. 2018.
27. Naozumi Ishimaru :
シェーグレン症候群における自己反応性獲得機序の解明,
Proceedings of the Japanese Society of Pathology, Vol.107, Jun. 2018.
28. Rieko Arakaki, Aya Ushio, Kunihiro Ohtsuka, Yasusei Kudo and Naozumi Ishimaru :
全身吸入暴露による多層化カーボンナノチューブの肺胞マクロファージへの影響,
Proceedings of the Japanese Society of Pathology, Vol.107, Jun. 2018.
29. Shinichiroh Nakayama, Rieko Arakaki, Aya Ushio, Kunihiro Ohtsuka, Takaaki Tsunematsu, Yasusei Kudo and Naozumi Ishimaru :
シェーグレン症候群モデルマウス唾液腺におけるIL-33の発現とその役割,
Proceedings of the Japanese Society of Pathology, Vol.107, Jun. 2018.
30. Saki Saijoh, Kunihiro Ohtsuka, Takaaki Tsunematsu, Kunihiro Ohtsuka, Aya Ushio, Rieko Arakaki, Yasusei Kudo and Naozumi Ishimaru :
Emi1の過剰発現による人工口腔癌幹細胞の作成,
Proceedings of the Japanese Society of Pathology, Vol.107, Jun. 2018.
31. Yukino Numata, Kunihiro Ohtsuka, Akiko Yamada, Aya Ushio, Takaaki Tsunematsu, Yasusei Kudo, Rieko Arakaki and Naozumi Ishimaru :
シェーグレン症候群疾患モデルにおけるNotchシグナルの役割,
Proceedings of the Japanese Society of Pathology, Vol.107, Jun. 2018.
32. Kunihiro Ohtsuka, Akiko Yamada, Masako Saito, Aya Ushio, Takaaki Tsunematsu, Yasusei Kudo, Rieko Arakaki and Naozumi Ishimaru :
シェーグレン症候群疾患モデルの自己免疫病変における濾胞ヘルパーT細胞の役割,
Proceedings of the Japanese Society of Pathology, Vol.107, Jun. 2018.
33. Aya Ushio, Rieko Arakaki, Akiko Yamada, Kunihiro Ohtsuka, Yasusei Kudo and Naozumi Ishimaru :
CCL22-producing resident macrophages enhancesnautoimmune lesions in a mouse model of Sjogren's syndorome.,
Proceedings of the Japanese Society for Immunology, Vol.46, 119, Dec. 2017.
34. Kunihiro Ohtsuka, Akiko Yamada, Aya Ushio, Mie Kurosawa, Rieko Arakaki, Yasusei Kudo and Naozumi Ishimaru :
Analysis of follicular helper T cells in a mouse model for Sjogren's syndorome.,
Proceedings of the Japanese Society for Immunology, Vol.46, 81, Dec. 2017.
35. Takashi Izawa, Rieko Arakaki, Eiji Tanaka and Naozumi Ishimaru :
Crosstalk between cytokine RANKL and AhR signaling in osteoclasts controls bone homeostasis (selected for oral presentation by English at Workshop "Cytokines and chemokines-2" and poster session),
Proceedings of the Japanese Society for Immunology, Vol.46, 36, Dec. 2017.
36. Izumi Ohigashi, Naozumi Ishimaru, Katakai Tomoya and Yousuke Takahama :
Essential role of CCL21 in establishment of central tolerance in T cells,
第40回 日本分子生物学会年会, Dec. 2017.
37. Takashi Izawa, Rieko Arakaki, Eiji Tanaka and Naozumi Ishimaru :
The nuclear receptor AhR controls bone homeostasis by regulating osteoclast differentiation via the RANK/c-Fos signaling axis,
ConBio2017 (Consortium of Biological Sciences 2017), 402, Dec. 2017.
38. S Afroz, Iwasa Takuma, Masamitsu Ohshima, Rieko Arakaki, Miho Inoue, Naozumi Ishimaru and Yoshizo Matsuka :
Cytokine released by satellite glial cells and pain transmission in sensory ganglions,
Japan Association for Dental Research, Nov. 2017.
39. Natsumi Takamaru, Hirokazu Nagai, Kazuya Akita, Yasusei Kudo, Naozumi Ishimaru and Youji Miyamoto :
翼突下顎隙に生じた紡錐細胞脂肪腫の1例,
第62回日本口腔外科学会学術大会, Oct. 2017.
40. Kunihiro Ohtsuka, Akiko Yamada, Yasusei Kudo, Rieko Arakaki and Naozumi Ishimaru :
シェーグレン症候群疾患モデルにおける胚中心反応の解析,
第26回日本シェーグレン症候群学会学術集会, Vol.26, Sep. 2017.
41. Kunihiro Ohtsuka, Akiko Yamada, Masako Saito, Aya Ushio, Satoko Kujiraoka, Mie Kurosawa, Takaaki Tsunematsu, Rieko Arakaki, Yasusei Kudo and Naozumi Ishimaru :
シェーグレン症候群疾患モデルにおける胚中心反応の解析,
第28回日本臨床口腔病理学会, Vol.28, Aug. 2017.
42. Takashi Izawa, Eiji Tanaka and Naozumi Ishimaru :
The nuclear receptor AhR controls bone homeostasis by regulating osteoclast differentiation via the RANK/c-Fos signaling axis,
The 35th Annual Meeting of the Japanese Society for Bone and Mineral Research (oral talk), Jul. 2017.
43. Kunihiro Ohtsuka, Yasusei Kudo and Naozumi Ishimaru :
シェーグレン症候群疾患モデルにおける胚中心反応の解析,
第36回分子病理学研究会, Vol.36, Jul. 2017.
44. Aya Ushio, Rieko Arakaki, Akiko Yamada, Kunihiro Ohtsuka, Mie Kurosawa, Yasusei Kudo and Naozumi Ishimaru :
シェーグレン症候群モデルマウスの唾液腺マクロファージと病態への関与,
第16回四国免疫フォーラム, Jun. 2017.
45. 宮本 由貴, Yukihiro Momota, Kohichi Kani, Fumihiro Matsumoto, Keiko Aota, Hideyuki Takano, 高瀬 奈緒, Tomoko Yamanoi, Shinji Ono, 牛尾 綾, Naozumi Ishimaru and Masayuki Azuma :
上顎に発生した石灰化を伴わない石灰化上皮性歯原性腫瘍の1例,
第46回日本口腔外科学会中国四国支部学術集会, May 2017.
46. 横田 美保, Keiko Kudoh, Tetsuya Tamatani, 鎌田 久美子, Naoyuki Fukuda, Natsumi Takamaru, Yoshiko Yamamura, Takayuki Nakagawa, Go Ohe, Takaharu Kudoh, Akira Takahashi, Kenji Fujisawa, 鯨岡 聡子, Yasusei Kudo, Naozumi Ishimaru and Youji Miyamoto :
当科における歯原性角化嚢胞の臨床的検討,
第46回日本口腔外科学会中国四国学術集会, May 2017.
47. Rieko Arakaki, Kohichi Yamada, Masako Saito, Kunihiro Ohtsuka, Akiko Yamada, Takaaki Tsunematsu, Yasusei Kudo, 菅野 純 and Naozumi Ishimaru :
Chronic influence of Multi-walled carbon nanotubes (MWCNT) on immune system,
第106回日本病理学会総会, Vol.106, Apr. 2017.
48. Takaaki Tsunematsu, Yasusei Kudo, Akiko Yamada, Rieko Arakaki, Hirohisa Ogawa, Koichi Tsuneyama and Naozumi Ishimaru :
胎児性癌細胞におけるユビキチンプロテアソーム経路による未分化性維持機構,
第106回日本病理学会総会, Vol.106, Apr. 2017.
49. Aya Ushio, Rieko Arakaki, Akiko Yamada, Kunihiro Ohtsuka, Satoko Kujiraoka, Takaaki Tsunematsu, Yasusei Kudo and Naozumi Ishimaru :
シェーグレン症候群の唾液腺におけるマクロファージサブセットと病態への関与,
第106回日本病理学会総会, Vol.106, Apr. 2017.
50. Satoko Kujiraoka, Yasusei Kudo, Takaaki Tsunematsu, Aya Ushio, Kunihiro Ohtsuka, Akiko Yamada, Rieko Arakaki and Naozumi Ishimaru :
歯原性明細胞癌細胞株の樹立とその性状解析,
第106回日本病理学会総会, Vol.106, Apr. 2017.
51. Masaaki Umeda, Takaaki Tsunematsu, Masako Saito, Akiko Yamada, Rieko Arakaki, Yasusei Kudo and Naozumi Ishimaru :
口腔癌におけるPeriostinスプライシングバリアントの新たな役割,
第106回日本病理学会総会, Vol.106, Apr. 2017.
52. Kunihiro Ohtsuka, Akiko Yamada, Masako Saito, Aya Ushio, Mie Kurosawa, Satoko Kujiraoka, Takaaki Tsunematsu, Yasusei Kudo, Rieko Arakaki and Naozumi Ishimaru :
シェーグレン症候群モデルマウスにおける濾胞ヘルパーT細胞の解析,
第106回日本病理学会総会, Vol.106, Apr. 2017.
53. Keiko Aota, 山ノ井 朋子, Kohichi Kani, Naozumi Ishimaru and Masayuki Azuma :
シェーグレン症候群におけるCXCR3+マクロファージの動態,
第71回日本口腔科学会学術集会, Apr. 2017.
54. Takaaki Tsunematsu, Yasusei Kudo, Akiko Yamada, Rieko Arakaki, Hirohisa Ogawa, Koichi Tsuneyama and Naozumi Ishimaru :
胎児性癌細胞におけるユビキチンプロテアソーム経路による未分化性維持機構,
Proceedings of the Japanese Society of Pathology, Vol.106, No.1, 356, Mar. 2017.
55. Rieko Arakaki, Kohichi Yamada, Aya Ushio, Mie Kurosawa, Kunihiro Ohtsuka, Masako Saito, Takaaki Tsunematsu, Akiko Yamada, Yasusei Kudo and Naozumi Ishimaru :
Immunological and toxicological effect of multi-wall carbon nanotubes by whole body inhalation exposure in B6 mice,
第45回日本免疫学会学術集会, Vol.45, Dec. 2016.
56. Akiko Yamada, Rieko Arakaki, Aya Ushio, Takaaki Tsunematsu, Yasusei Kudo and Naozumi Ishimaru :
1)Impaired Expansion of Regulatory T cells in a Murine model of Neonatal Thymectomy-induced Sjogrens Syndrome,
第45回日本免疫学会学術集会, Vol.45, Dec. 2016.
57. Kunihiro Ohtsuka, Masako Saito, Mie Kurosawa, Aya Ushio, Akiko Yamada, Rieko Arakaki, Yasusei Kudo and Naozumi Ishimaru :
Analysis of follicular helper T cells in a mouse model for Sjogren's syndrome.,
第45回日本免疫学会学術集会, Vol.45, Dec. 2016.
58. Aya Ushio, Rieko Arakaki, Masako Saito, Akiko Yamada, Kunihiro Ohtsuka, Mie Kurosawa, Satoko Kujiraoka, Yasusei Kudo and Naozumi Ishimaru :
Analysis of macrophages in the pathogenesis of a murine model for Sjogren's syndrome.,
第45回日本免疫学会学術集会, Vol.45, Dec. 2016.
59. Keiko Aota, Tomoko Yamanoi, Kohichi Kani, Naozumi Ishimaru and Masayuki Azuma :
ヒト唾液腺細胞株における CXCL10 の発現機能解析,
第53回日本口腔組織培養学会学術大会, Nov. 2016.
60. Masahiro Hiasa, Ryota Amachi, Hirofumi Tenshin, Shinya Horiuchi, Masahiro Abe, Naozumi Ishimaru and Eiji Tanaka :
RelBは古典的NF-κB経路の活性化を阻害し骨癒合不全と偽関節形成を予防する,
日本矯正歯科学会大会プログラム・抄録集., 192., Nov. 2016.
61. Kunihiro Ohtsuka, Aya Ushio, 宮本 由貴, Satoko Kujiraoka, Akiko Yamada, Keiko Aota, Yasusei Kudo, Masayuki Azuma and Naozumi Ishimaru :
1,
第64回日本口腔科学会中国四国地方部会, Vol.64, Oct. 2016.
62. 高瀬 奈緒, Yukihiro Momota, Kohichi Kani, 宮本 由貴, 山ノ井 朋子, Shinji Ono, Hideyuki Takano, Keiko Aota, Fumihiro Matsumoto, 牛尾 綾, Naozumi Ishimaru and Masayuki Azuma :
上唇粘膜下に生じた血管筋腫の1例,
第64回日本口腔科学会中四国地方部会, Oct. 2016.
63. 横田 美保, Kenji Fujisawa, Yoshiko Yamamura, Tetsuya Tamatani, Natsumi Takamaru, Keiko Kudoh, Go Ohe, Hirokazu Nagai, 鯨岡 聡子, Naozumi Ishimaru and Youji Miyamoto :
骨破壊を伴った顎放線菌症の2例,
第64回NPO法人日本口腔科学会中国・四国地方部会, Oct. 2016.
64. Aya Ushio, Rieko Arakaki, Kunihiro Ohtsuka, Masako Saito, Akiko Yamada, Yasusei Kudo and Naozumi Ishimaru :
シェーグレン症候群の病態形成におけるマクロファージの役割,
日本シェーグレン症候群学会, Vol.25, Sep. 2016.
65. Kunihiro Ohtsuka, Masako Saito, Aya Ushio, Akiko Yamada, Rieko Arakaki, Yasusei Kudo and Naozumi Ishimaru :
シェーグレン症候群モデルにおける濾胞ヘルパーT細胞の機能解析,
日本シェーグレン症候群学会, Vol.25, Sep. 2016.
66. Aya Ushio, Yasusei Kudo, Satoko Kujiraoka, Kunihiro Ohtsuka, Takaaki Tsunematsu, Akiko Yamada and Naozumi Ishimaru :
上顎骨腫瘍,
日本臨床口腔病理学会総会・学術集会, Vol.27, Aug. 2016.
67. Satoko Kujiraoka, Yasusei Kudo, Takaaki Tsunematsu, Aya Ushio, Kunihiro Ohtsuka, Akiko Yamada and Naozumi Ishimaru :
小児に発生した歯原性下顎骨腫瘍の1例,
日本臨床口腔病理学会総会・学術集会, Vol.27, Aug. 2016.
68. Masaaki Umeda, Takaaki Tsunematsu, Masako Saito, Akiko Yamada, Rieko Arakaki, Yasusei Kudo and Naozumi Ishimaru :
口腔扁平上皮癌におけるPeriostinスプライシングバリアントの新たな役割,
第27回日本臨床口腔病理学会総会・学術大会, Aug. 2016.
69. 高瀬 奈緒, Keiko Aota, 宮本 由貴, 山ノ井 朋子, Shinji Ono, Hideyuki Takano, Kohichi Kani, Yukihiro Momota, Naozumi Ishimaru and Masayuki Azuma :
口蓋に生じた筋上皮腫の1例,
第45回日本口腔外科学会中四国支部学術集会, May 2016.
70. Rieko Arakaki, Takaaki Tsunematsu, Akiko Yamada, Masako Saito, Yasusei Kudo and Naozumi Ishimaru :
全身吸入暴露による多層化カーボンナノチューブの免疫システムへの影響,
第105回日本病理学会総会, Vol.105, No.1, May 2016.
71. Aya Ushio, Masako Saito, Akiko Yamada, Kunihiro Ohtsuka, Mie Kurosawa, Satoko Kujiraoka, Yasusei Kudo and Naozumi Ishimaru :
シェーグレン症候群モデルマウスの病態形成におけるマクロファージの役割,
第105回日本病理学会総会, Vol.105, No.1, May 2016.
72. Satoko Kujiraoka, Yasusei Kudo, Takaaki Tsunematsu, Tomoyuki Kondoh, Aya Ushio, Kunihiro Ohtsuka, Akiko Yamada, Rieko Arakaki and Naozumi Ishimaru :
顎骨中心性明細胞性腫瘍からの細胞株の樹立とその性状,
第105回日本病理学会総会, Vol.105, No.1, May 2016.
73. 山ノ井 朋子, Keiko Aota, Hideyuki Takano, Kohichi Kani, Fumihiro Matsumoto, Yukihiro Momota, 高瀬 奈緒, 宮本 由貴, Naozumi Ishimaru and Masayuki Azuma :
シェーグレン症候群患者におけるセファランチンの作用機序の解明,
第70回日本口腔科学会学術集会, Apr. 2016.
74. Keiko Aota, 山ノ井 朋子, Kohichi Kani, Hideyuki Takano, Yukihiro Momota, Fumihiro Matsumoto, Naozumi Ishimaru and Masayuki Azuma :
Sjögren 症候群唾液腺における IP-10 の発現制御機構,
第70回日本口腔科学会学術集会, Apr. 2016.
75. Takaaki Tsunematsu, Yasusei Kudo, Akiko Yamada, Rieko Arakaki, Hirohisa Ogawa, Hisanori Uehara, Naozumi Ishimaru and Koichi Tsuneyama :
染色体パッセンジャー複合体タンパク質Borealinのユビキチン分解の意義とその癌化への関与,
Proceedings of the Japanese Society of Pathology, Vol.105, No.1, 548, Apr. 2016.
76. Masako Saito, Rieko Arakaki, Kunihiro Ohtsuka, Kohichi Yamada, Yasusei Kudo and Naozumi Ishimaru :
Biological effect of Multi-Walled Carbon Nanotubes(MWCNTs)on imune system.,
Proceedings of the Japanese Society for Immunology, Nov. 2015.
77. Rieko Arakaki, Aya Ushio, Mie Kurosawa, Kunihiro Ohtsuka, Akiko Yamada, Masako Saito, Takaaki Tsunematsu, Yasusei Kudo and Naozumi Ishimaru :
Analysis of function of macrophages in murine models of Sjogren's syndorome.,
Proceedings of the Japanese Society for Immunology, Nov. 2015.
78. Mie Kurosawa, Akiko Yamada, Rieko Arakaki, Masako Saito, Takaaki Tsunematsu, Yasusei Kudo and Naozumi Ishimaru :
Migratory activity of memory T cells in aly/aly mice.,
Proceedings of the Japanese Society for Immunology, Nov. 2015.
79. Tomoyuki Kondoh, Takaaki Tsunematsu, Yasusei Kudo and Naozumi Ishimaru :
自己免疫疾患モデルにおける腫瘍増殖の亢進,
第74回日本癌学会学術総会, Oct. 2015.
80. 古川 貴大, Naoko Matsui, 高橋 利幸, Naozumi Ishimaru and Ryuji Kaji :
耳下腺炎後に視神経や脊髄以外に広範な白質病変を来し,抗AQP4抗体が陽性であったシェーグレン症候群の1例,
神経免疫学, Vol.20, No.1, 114, Sep. 2015.
81. Takaaki Tsunematsu, Yasusei Kudo, Tomoyuki Kondoh, Aya Ushio, Satoko Kujiraoka, Akiko Yamada, Rieko Arakaki and Naozumi Ishimaru :
染色体パッセンジャー複合体タンパク質Borealinのユビキチン分解とその癌化への関与,
日本病理学会会誌, Vol.104, No.1, 504, May 2015.
82. Satoko Kujiraoka, Yasusei Kudo, Takaaki Tsunematsu, Tomoyuki Kondoh, Aya Ushio, Akiko Yamada, Rieko Arakaki and Naozumi Ishimaru :
口腔癌細胞におけるペリオスチンのスプライシングバリアントの発現とその意義,
日本病理学会会誌, Vol.104, No.1, 497, Apr. 2015.
83. Tomoyuki Kondoh, Takaaki Tsunematsu, Satoko Kujiraoka, Satoko Kujiraoka, Aya Ushio, Akiko Yamada, Rieko Arakaki, Yasusei Kudo and Naozumi Ishimaru :
自己免疫疾患モデルを用いた腫瘍増殖制御機構の解明,
日本病理学会会誌, Vol.104, No.1, 497, Apr. 2015.
84. Aya Ushio, Rieko Arakaki, Tomoyuki Kondoh, Satoko Kujiraoka, Takaaki Tsunematsu, Akiko Yamada, Yasusei Kudo and Naozumi Ishimaru :
Analysis of macrophages in the pathogenesis of a murine for Sjogren's syndorome.,
日本病理学会会誌, Vol.104, No.1, 450, Apr. 2015.
85. Yasusei Kudo, Takaaki Tsunematsu, Satoko Kujiraoka, Tomoyuki Kondoh, Aya Ushio, Akiko Yamada, Rieko Arakaki and Naozumi Ishimaru :
顎骨中心性粘表皮癌細胞株の樹立とその性状,
日本病理学会会誌, Vol.104, No.1, 401, Apr. 2015.
86. Rieko Arakaki, Takaaki Tsunematsu, Akiko Yamada, Yasusei Kudo, 菅野 純 and Naozumi Ishimaru :
自己免疫疾患モデルマウスを利用した多層化カーボンナノチューブの免疫システムへの影響,
日本病理学会会誌, Vol.104, No.1, 380, Apr. 2015.
87. Aya Ushio, Rieko Arakaki, Mie Kurosawa, Tomoyuki Kondoh, Satoko Kujiraoka, Akiko Yamada, Yasusei Kudo and Naozumi Ishimaru :
Analysis of macrophages in the pathogenesis of murine models for Sjogren's syndorome.,
Proceedings of the Japanese Society for Immunology, Dec. 2014.
88. Rieko Arakaki, Aya Ushio, Kohichi Yamada, Mie Kurosawa, Satoko Kujiraoka, Tomoyuki Kondoh, 常松 貴明, Akiko Yamada, Yasusei Kudo and Naozumi Ishimaru :
Influence of multi-wall carbon nanotubes on immune system in nomal mice and MRL/lpr mice.,
Proceedings of the Japanese Society for Immunology, Dec. 2014.
89. Mie Kurosawa, Akiko Yamada, Rieko Arakaki, Tomoyuki Kondoh, 常松 貴明, Yasusei Kudo, Satoko Kujiraoka, Aya Ushio and Naozumi Ishimaru :
A novel role of CXCR7 in memory T cells of a murine model for Sjogren's syndorome.,
Proceedings of the Japanese Society for Immunology, Dec. 2014.
90. Naozumi Ishimaru :
病気と研究∼自己免疫疾患の克服にむけて∼,
九州歯科大学, Dec. 2014.
91. Naozumi Ishimaru :
シェーグレン症候群の病態機序,
日本皮膚科四国地方会, Dec. 2014.
92. Satoko Kujiraoka, Yasusei Kudo, 常松 貴明 and Naozumi Ishimaru :
口腔癌細胞におけるペリオスチンのスプライシングバリアントの発現とその意義,
第37回日本分子生物学会, Nov. 2014.
93. Takaharu Kudoh, Nobuyuki Kuribayashi, Keiko Kudoh, Go Ohe, Masako Fujioka-Kobayashi, Tetsuya Tamatani, Hirokazu Nagai, 近藤 智之, Naozumi Ishimaru and Youji Miyamoto :
舌に発生した孤立性神経線維腫の1例,
第62回NPO法人日本口腔科学会中国・四国地方部会, Oct. 2014.
94. Aya Ushio, Rieko Arakaki, Mie Kurosawa, Tomoyuki Kondoh, Satoko Kujiraoka, 常松 貴明, Akiko Yamada, Yasusei Kudo and Naozumi Ishimaru :
シェーグレン症候群モデルマウスの標的臓器におけるマクロファージの役割,
日本シェーグレン症候群学会学術集会, Sep. 2014.
95. Yosuke Shikama, Yasusei Kudo, Naozumi Ishimaru and Makoto Funaki :
飽和脂肪酸が歯周病の病態形成に関与する可能性(Possibility of involvement of saturated fatty acids in pathogenesis of periodontitis),
Journal of Oral Biosciences Supplement, Vol.2014, 161, Sep. 2014.
96. Tomoyuki Kondoh, 常松 貴明, Mie Kurosawa, Satoko Kujiraoka, Aya Ushio, Akiko Yamada, Rieko Arakaki, Yasusei Kudo and Naozumi Ishimaru :
Analysis of regulatory mechanism of tumor immunity using an animal model for autoimmunity.,
第25回日本臨床口腔病理学会, Aug. 2014.
97. Aya Ushio, Rieko Arakaki, Mie Kurosawa, Tomoyuki Kondoh, Satoko Kujiraoka, 常松 貴明, Akiko Yamada, Yasusei Kudo and Naozumi Ishimaru :
Analysis of macrophages in the pathogenesis of Sjogren's syndrome using murine models.,
第25回日本臨床口腔病理学会, Aug. 2014.
98. Satoko Kujiraoka, Yasusei Kudo, 常松 貴明, Tomoyuki Kondoh, Aya Ushio, Mie Kurosawa, Akiko Yamada, Rieko Arakaki and Naozumi Ishimaru :
The role of splicing variants of periostin in oral cancer cells.,
第25回日本臨床口腔病理学会, Aug. 2014.
99. Tomoyuki Kondoh, Satoko Kujiraoka, Aya Ushio, Mie Kurosawa, 常松 貴明, Akiko Yamada, Rieko Arakaki, Yasusei Kudo and Naozumi Ishimaru :
自己免疫疾患モデルを用いた腫瘍増殖抑制機構の解明,
免疫サマースクール2014, Jul. 2014.
100. Tomoyuki Kondoh, Satoko Kujiraoka, Aya Ushio, Mie Kurosawa, 常松 貴明, Akiko Yamada, Rieko Arakaki, Yasusei Kudo and Naozumi Ishimaru :
自己免疫疾患モデルを用いた腫瘍増殖制御機構の解明,
第33回分子病理学研究会, Jul. 2014.
101. Keiko Aota, Yoshiko Yamamura, Kohichi Kani, Hideyuki Takano, Katsumi Motegi, Fumihiro Matsumoto, Naozumi Ishimaru and Masayuki Azuma :
ドライマウス患者における唾液中のTNF-αとMMP-9発現に関する研究,
第68回日本口腔科学会学術集会, May 2014.
102. Yasusei Kudo, 常松 貴明, Tomoyuki Kondoh, Mie Kurosawa, Akiko Yamada, Rieko Arakaki and Naozumi Ishimaru :
癌細胞におけるペリオスチンのスプライシングバリアントの発現とEMTとの関連,
日本病理学会会誌, Vol.103, No.1, 268, Apr. 2014.
103. Akiko Yamada, Rieko Arakaki, Mie Kurosawa, Tomoyuki Kondoh, 常松 貴明, Yasusei Kudo, Yoshio Hayashi and Naozumi Ishimaru :
シェーグレン症候群の発症における制御性T細胞の役割,
日本病理学会会誌, Vol.103, No.1, 268, Apr. 2014.
104. Rieko Arakaki, Akiko Yamada, Yasusei Kudo, Yoshio Hayashi and Naozumi Ishimaru :
ニッケルアレルギー発症におけるThmic Stromal Lymphopoiethinの重要性,
日本病理学会会誌, Vol.103, No.1, 268, Apr. 2014.
105. Naozumi Ishimaru :
シェーグレン症候群の発症機序の解明,
日本口腔外科学会中国四国支部集会, Apr. 2014.
106. 常松 貴明, Yasusei Kudo, Tomoyuki Kondoh, Mie Kurosawa, Akiko Yamada, Rieko Arakaki and Naozumi Ishimaru :
ユビキチン分解による複製前複合体形成因子CDT1の発現制御機構の解析,
日本病理学会会誌, Vol.103, No.1, 268, Apr. 2014.
107. Tomoyuki Kondoh, Mie Kurosawa, 常松 貴明, Akiko Yamada, Rieko Arakaki, Yasusei Kudo and Naozumi Ishimaru :
自己免疫疾患モデルを用いた腫瘍免疫制御機構の解析,
日本病理学会会誌, Vol.103, No.1, 268, Apr. 2014.
108. Mie Kurosawa, Naozumi Ishimaru, Rieko Arakaki, Akiko Yamada, Yasusei Kudo and Tomoyuki Kondoh :
Anovel role of CXCR7 in controlling autoreactive T cells of a murine model for Sjogren's syndorome.,
Proceedings of the Japanese Society for Immunology, Dec. 2013.
109. Akihiko Iwasa, Mie Kurosawa, Rieko Arakaki, Akiko Yamada, Eiji Tanaka, Yasusei Kudo and Naozumi Ishimaru :
Relationship between aromatase-related obesity and autoimmunity in Sjogren's syndorome.,
Proceedings of the Japanese Society for Immunology, Dec. 2013.
110. Rieko Arakaki, Hiroshi Eguchi, Akiko Yamada, Yasusei Kudo, Yoshinori Mitamura, Yoshio Hayashi and Naozumi Ishimaru :
Eye drop administration of rebamipide is effective to a dry eye symptom in a model mice of Sjogren's syndorome.,
Proceedings of the Japanese Society for Immunology, Dec. 2013.
111. Yasusei Kudo, 常松 貴明 and Naozumi Ishimaru :
Aurora-A controls pre-replicative complex formation and DNA replication by promoting the stabilization of geminin and CDT1 in mitosis.,
第36回日本分子生物学会年会, Dec. 2013.
112. Akihiko Iwasa, Naozumi Ishimaru, Takashi Izawa, 徳永 律子, Yasusei Kudo and Eiji Tanaka :
アロマターゼ遺伝子欠損マウスにおけるシェーグレン症候群様病変と肥満との関連,
第72回日本矯正歯科学会大会プログラム・抄録集, Oct. 2013.
113. Tomoyuki Kondoh, Akiko Yamada, Rieko Arakaki, Yasusei Kudo and Naozumi Ishimaru :
自己免疫疾患モデルを用いた腫瘍免疫システムの解析,
Japanese Journal of Oral Biology, Sep. 2013.
114. Naozumi Ishimaru :
シェーグレン症候群の病理診断の新機軸,
第22回日本シェーグレン症候群学会学術集会, Sep. 2013.
115. Tomoyuki Kondoh, Yasusei Kudo and Naozumi Ishimaru :
自己免疫疾患モデルを用いた腫瘍免疫システムの解析,
第32回分子病理学研究会, Jul. 2013.
116. Yasusei Kudo, Takaaki Tsunematsu and Naozumi Ishimaru :
Aurora-A controls pre-replicative complex formation and DNA replication by promoting the stabilization of geminin and Cdt1 in mitosis,
第35回Naito Conference, Jul. 2013.
117. Akihiko Iwasa, Rieko Arakaki, Akiko Yamada, Yasusei Kudo and Naozumi Ishimaru :
アロマターぜ遺伝子欠損マウスにおけるシェーグレン症候群様病変と肥満との関連,
四国免疫ファオーラム, Jun. 2013.
118. Akiko Yamada, Rieko Arakaki, Mie Kurosawa, Tomoyuki Kondoh, Yasusei Kudo and Naozumi Ishimaru :
シェーグレン症候群における制御性T細胞の機能解析,
第102回日本病理学会, Jun. 2013.
119. Rieko Arakaki, Akiko Yamada, Yasusei Kudo, Hiroshi Eguchi, Yoshinori Mitamura, Yoshio Hayashi and Naozumi Ishimaru :
シェーグレン症候群モデルを用いたレバミピド点眼薬によるドライアイの改善効果とその作用機序,
第102回日本病理学会, Jun. 2013.
120. Tomoyuki Kondoh, Yasusei Kudo, Akiko Yamada and Naozumi Ishimaru :
自己免疫疾患モデルを用いた腫瘍免疫システムの解析,
第102回日本病理学会, Jun. 2013.
121. Akihiko Iwasa, Tomoyuki Kondoh, Mie Kurosawa, Rieko Arakaki, Akiko Yamada, Eiji Tanaka, Yasusei Kudo and Naozumi Ishimaru :
アロマターゼ遺伝子欠損マウスにおける肥満とシェーグレン症候群様病変との関連,
第102回日本病理学会, Jun. 2013.
122. Keiko Aota, Yoshiko Yamamura, Kohichi Kani, Hideyuki Takano, Yukihiro Momota, Fumihiro Matsumoto, Naozumi Ishimaru and Masayuki Azuma :
シェーグレン症候群に対する新規治療戦略―唾液腺腺房構造の破壊を阻止する-,
第67回日本口腔科学会学術集会, May 2013.
123. Tomoyuki Kondoh, Yasusei Kudo and Naozumi Ishimaru :
自己免疫疾患モデルを用いた腫瘍免疫システムの解析,
Journal of The Japanese Stomatological Society, Vol.67, 200, May 2013.
124. Hiroyuki Mizuguchi, 服部 将史, 馬場 祐子, 張 倩, 小林 誠, Naozumi Ishimaru, Yoshiaki Kitamura, Noriaki Takeda and Hiroyuki Fukui :
タンパクキナーゼCδシグナル抑制化合物ケルセチンのストレプトゾトシン誘発β細胞破壊に対する効果,
日本薬学会 第133回年会, Mar. 2013.
125. 服部 将史, Hiroyuki Mizuguchi, 馬場 祐子, 小野 将平, 張 倩, 小林 誠, Naozumi Ishimaru, Yoshiaki Kitamura, Noriaki Takeda and Hiroyuki Fukui :
Effect of quercetin on streptozotocin-induced diabetic mice.,
第86回日本薬理学会年会, Mar. 2013.
126. Nobuyuki Kuribayashi, Hirokazu Nagai, Daisuke Uchida, 木内 誠, Tetsuya Tamatani, Kenji Fujisawa, Naozumi Ishimaru and Youji Miyamoto :
頬粘膜に生じた明細胞癌NOSの1例,
第31回日本口腔腫瘍学会総会・学術大会, Jan. 2013.
127. Yosuke Shikama, Naozumi Ishimaru, Yukiko Bandou, Nanako Aki and Makoto Funaki :
Palmitate induces IL-6 production and α-fodrin degradation in salivary gland epithelial cells,
Journal of the The Japan Diabetes Society, Vol.56, No.Suppl.1, S-186, 2013.
128. Naozumi Ishimaru :
Molecular Pathogenesis of Sjogrens Syndrome,
JADR, Dec. 2012.
129. Rieko Arakaki, Hiroshi Eguchi, Akiko Yamada, Yasusei Kudo, Yoshinori Mitamura, Yoshio Hayashi and Naozumi Ishimaru :
An Effective Therapy of Ocular Lesions in a Murine Model for Sjogren's Syndorome by Eye Drop Administration of Rebamipide.,
Proceedings of the Japanese Society for Immunology, Dec. 2012.
130. Mie Kurosawa, Akiko Yamada, Rieko Arakaki, Tomoyuki Kondo, Yasusei Kudo and Naozumi Ishimaru :
Analysis of infiltrating immune cells in the target tissues of murine models for Sjogren's syndorome.,
Proceedings of the Japanese Society for Immunology, Dec. 2012.
131. Akiko Yamada, Rieko Arakaki, Mie Kurosawa, Tomoyuki Kondo, Yasusei Kudo, Yoshio Hayashi and Naozumi Ishimaru :
Functional defect of Foxp3+Treg cells in Sjogren's syndrome.,
Proceedings of the Japanese Society for Immunology, Dec. 2012.
132. Akihiko Iwasa, Rieko Arakaki, Akiko Yamada, Eiji Tanaka, Yasusei Kudo and Naozumi Ishimaru :
The dysfunction of the aromatase worsens the pathogenesis of Sjogren's syndrome.,
Proceedings of the Japanese Society for Immunology, Dec. 2012.
133. Daisuke Tsuji, 難波 建多郎, Naozumi Ishimaru, 櫻庭 均 and Kouji Itou :
Tay-Sachs病患者由来iPS細胞の樹立と分化神経系細胞に対する酵素補充効果の検討,
第54回日本先天代謝異常学会総会/第11回アジア先天代謝異常症シンポジウム, Nov. 2012.
134. Hirokazu Nagai, Kenji Fujisawa, Natsumi Takamaru, Daisuke Uchida, Tetsuya Tamatani, Go Ohe, Naozumi Ishimaru and Youji Miyamoto :
頬部に生じた粘液種の1例,
第57回公益社団法人日本口腔外科学会, Oct. 2012.
135. 近藤 智之, Akiko Yamada, Yasusei Kudo and Naozumi Ishimaru :
口蓋に生じた悪性リンパ腫の2症例,
第60回日本口腔科学会中国・四国地方部会, Oct. 2012.
136. 近藤 智之, Akiko Yamada, Yasusei Kudo and Naozumi Ishimaru :
口蓋に生じた悪性リンパ腫の2症例,
第23回日本臨床口腔病理学会, Sep. 2012.
137. Yasusei Kudo, 常松 貴明, 近藤 智之, Naozumi Ishimaru and Takashi Takata :
Chromosome passenger complex protein,Borealin is regulated by APC/C-Cdh1 ubiquitin ligase complex,
Proceedings of the Japanese Cancer Association, Sep. 2012.
138. Akiko Yamada, Rieko Arakaki, 黒澤 愛実, 近藤 智之, Yasusei Kudo and Naozumi Ishimaru :
シェーグレン症候群における制御性T細胞の役割,
第21回日本シェーグレン症候群学会, Sep. 2012.
139. Rieko Arakaki, Akiko Yamada, Yasusei Kudo and Naozumi Ishimaru :
エストロゲン欠乏によって増悪されるシェーグレン症候群病態へのTh17細胞の関与,
Japanese Journal of Oral Biology, Vol.54, 145-145, Sep. 2012.
140. 服部 将史, Hiroyuki Mizuguchi, 馬場 祐子, 張 倩, 小林 誠, 小野 将平, Naozumi Ishimaru and Hiroyuki Fukui :
プロテインキナーゼC(PKC)-δシグナル抑制効果をもつ新規抗糖尿病薬開発及び糖尿病発症メカニズムの解明,
第11回 次世代を担う若手ファーマ・バイオフォーラム2012, Sep. 2012.
141. Naozumi Ishimaru :
シェーグレン症候群の臨床応用研究,
第23回日本臨床口腔病理学会, Aug. 2012.
142. Naozumi Ishimaru :
シェーグレン症候群の発症機序と臨床応用研究,
第23回日本臨床口腔病理学会, Aug. 2012.
143. Akihiko Iwasa, Rieko Arakaki, Akiko Yamada, Yasusei Kudo and Naozumi Ishimaru :
A critical role of aromatase in the pathogenesis of Sjogren's syndrome,
第31回分子病理学研究会, Jul. 2012.
144. Masahiro Hiasa, Masahiro Abe, Rieko Arakaki, Akiko Yamada, Kenzo Asaoka, Toshio Matsumoto, Yoshio Hayashi and Naozumi Ishimaru :
RelB antagonizes the classical NF-κB pathway and its suppression of osteoblastogenesis,
第30回日本骨代謝学会, Jul. 2012.
145. Keiko Aota, Katsumi Motegi, Yukihiro Momota, Naozumi Ishimaru and Masayuki Azuma :
シェーグレン症候群患者の唾液腺腺房構造破壊阻止―セファランチンの有効性に関する臨床病理学的研究―,
第66回日本口腔科学会 学術総会, May 2012.
146. Akiko Yamada, Rieko Arakaki, Yoshio Hayashi and Naozumi Ishimaru :
シェーグレン症候群における制御性T細胞の役割,
第101回日本病理学会, Apr. 2012.
147. Ritsuko 徳永 律子 Oura, Rieko Arakaki, Akiko Yamada, Yoshio Hayashi and Naozumi Ishimaru :
Fas分子を介したマクロファージによる末梢T細胞の維持機構,
第101回日本病理学会, Apr. 2012.
148. Naozumi Ishimaru, Akiko Yamada, Rieko Arakaki and Yoshio Hayashi :
自己免疫疾患におけるCCR7を介した制御性T細胞のパトローリング機能,
第101回日本病理学会, Apr. 2012.
149. Rieko Arakaki, Akiko Yamada, Yoshio Hayashi, Hiroshi Eguchi, 三田村 さやか, 堀田 芙美香, Yoshinori Mitamura and Naozumi Ishimaru :
シェーグレン症候群モデルマウスを利用したレバミピド点眼投与による病態抑制機序の解明,
第101回日本病理学会, Apr. 2012.
150. Naozumi Ishimaru :
ライフサイエンスにおける口腔病理学の新展開,
四国歯学会教授就任講演, Mar. 2012.
151. Naozumi Ishimaru :
Analysis of Organ-Specific Autoimmune Disease,
New Horizons in the Immune System Symposium, Feb. 2012.
152. Naozumi Ishimaru :
口腔乾燥症の病態機序と治療戦略,
第7回次世代医療システム産業化フォーラム, Jan. 2012.
153. Kazuma Matsumoto, Rieko Arakaki, Akiko Yamada, Masahiro Hiasa, Ritsuko 徳永 律子 Oura, 岩浅 亮彦, Eiji Tanaka, Yoshio Hayashi and Naozumi Ishimaru :
Hyperfunctions of osteoclasts in pathogenesis of rheumatoid arthritis in MRL/lpr mice.,
第40回日本免疫学会学術集会, Nov. 2011.
154. Masahiro Hiasa, Rieko Arakaki, Akiko Yamada, Ritsuko 徳永 律子 Oura, Masahiro Abe, Toshio Matsumoto, Yoshio Hayashi, Naozumi Ishimaru and Kenzo Asaoka :
A novel role of NF-B relB in bone remodeling.,
第40回日本免疫学会学術集会, Nov. 2011.
155. Ritsuko 徳永 律子 Oura, Rieko Arakaki, Masahiro Hiasa, Akiko Yamada, Eiji Tanaka, Yoshio Hayashi and Naozumi Ishimaru :
In vivo T cell apoptosis via interaction with CD11b+ macrophages in Fas-deficient host.,
Proceedings of the Japanese Society for Immunology, Vol.40, 111, Nov. 2011.
156. Akihiko Iwasa, Rieko Arakaki, Akiko Yamada, Eiji Tanaka, Yoshio Hayashi and Naozumi Ishimaru :
A critical role of aromatase in the pathogenesis of Sjogren's syndrome.,
Proceedings of the Japanese Society for Immunology, Vol.40, 127, Nov. 2011.
157. Rieko Arakaki, Akiko Yamada, Yoshio Hayashi and Naozumi Ishimaru :
The role of Th17 cell on the development of Sjogren's syndrome in estrogen deficient NOD mice.,
Proceedings of the Japanese Society for Immunology, Vol.40, 128, Nov. 2011.
158. Nur Meinar Ashrin, Megumi Watanabe, Rieko Arakaki, Akiko Yamada, Tetsuo Ichikawa, Yoshio Hayashi and Naozumi Ishimaru :
Analysis of Immune Responess to Metal using Murine Nickel Allergy Model.,
Proceedings of the Japanese Society for Immunology, Vol.40, 102, Nov. 2011.
159. Naozumi Ishimaru :
口腔免疫疾患の分子メカニズムと治療戦略,
日本口腔科学会中四国支部会, Nov. 2011.
160. Naozumi Ishimaru :
口腔免疫疾患の分子メカニズムと治療戦略,
第59回NPO法人日本口腔科学会中国・四国地方部会, Nov. 2011.
161. Naozumi Ishimaru :
免疫学から見た病理学,
日本臨床衛生検査所中四国支部会, Nov. 2011.
162. Naozumi Ishimaru :
口腔乾燥症の病態機序と治療戦略,
徳島大学大学院ヘルスバイオサイエンス研究部公開市民講座, Nov. 2011.
163. Naozumi Ishimaru :
イメージング技術を用いた臓器特異的自己免疫疾患の病態解明,
第3回革新的特色研究シンポジウム, Nov. 2011.
164. 近藤 真代, Hiroshi Kawano, Souji Kakiuchi, Jun Kishi, Masaki Hanibuchi, Masahiko Azuma, 近藤 絵里, Masakazu Goda, Naozumi Ishimaru and Yasuhiko Nishioka :
IgG4関連下垂体炎の1例,
第105回日本内科学会四国地方会, Nov. 2011.
165. Natsumi Takamaru, Hirokazu Nagai, Go Ohe, Daisuke Uchida, Tetsuya Tamatani, Naozumi Ishimaru and Youji Miyamoto :
下顎骨に発生した歯原性粘液腫の1例,
第 56回日本口腔外科学会総会・学術大会, Oct. 2011.
166. Kazuma Matsumoto, Naozumi Ishimaru, Takashi Izawa, Masahiro Hiasa, Ritsuko 徳永 律子 Oura, Akihiko Iwasa, Yoshio Hayashi and Eiji Tanaka :
関節リウマチモデルマウスにおける破骨細胞の機能亢進,
日本矯正歯科学会大会プログラム・抄録集, 218, Oct. 2011.
167. Naozumi Ishimaru :
臓器特異的自己免疫疾患の病態解明に向けた多角的研究,
第53回歯科基礎医学会学術大会, Oct. 2011.
168. Kazuma Matsumoto, Naozumi Ishimaru, Takashi Izawa, Masahiro Hiasa, Eiji Tanaka and Yoshio Hayashi :
関節リウマチモデルマウスにおける破骨細胞の機能解析,
日本骨代謝学会学術大会, 256, Jul. 2011.
169. Naozumi Ishimaru :
口腔乾燥症の病態機序と治療戦略,
第9回徳島大学研究者との集い, Jul. 2011.
170. Kazuma Matsumoto, Naozumi Ishimaru, Takashi Izawa, Ritsuko 徳永 律子 Oura, Akihiko Iwasa, Yoshio Hayashi and Eiji Tanaka :
Analysis for mechanism of T cell activation via osteoclast in rheumatoid arthritis,
Journal of the Japanese Society for the Temporomandibular Joint, Vol.23, 102, Jul. 2011.
171. Naozumi Ishimaru :
自己免疫疾患発症機序の解明∼疾患モデルから臨床応用に向けて∼,
第30回分子病理学研究会瀬戸内シンポジウム, Apr. 2011.
172. Kazuma Matsumoto, Naozumi Ishimaru, Rieko Arakaki, Akiko Yamada, Eiji Tanaka and Yoshio Hayashi :
関節リウマチ病態における破骨細胞を介したT細胞活性化機構の解析,
第100回日本病理学会学術集会, Vol.100, No.1, 60, Apr. 2011.
173. Rieko Arakaki, Naozumi Ishimaru, Akiko Yamada and Yoshio Hayashi :
エストロゲン欠乏によって誘導されるシェーグレン症候群病態増強へのTh17細胞の関与,
第100回日本病理学会学術集会, Vol.100, No.1, 63, Apr. 2011.
174. Naozumi Ishimaru, Akiko Yamada, Rieko Arakaki and Yoshio Hayashi :
自己免疫疾患の病態におけるメモリーCD8陽性T細胞の役割,
第100回日本病理学会学術集会, Vol.100, No.1, 59, Apr. 2011.
175. Naozumi Ishimaru, 本間 尚子, 吉村 憲子, 原田 信広 and Yoshio Hayashi :
自己免疫疾患におけるアロマターゼの役割,
第18回ステロイドホルモン学会学術集会, Nov. 2010.
176. Kazuma Matsumoto, Naozumi Ishimaru, Takashi Izawa, Yoshio Hayashi and Eiji Tanaka :
Analysis of osteoclast activation in the pathogenesis of rheumatoid arthritis,
58th JADR, Nov. 2010.
177. Hiroyuki Mizuguchi, 玉田 美咲, Naozumi Ishimaru, Yoshiaki Kitamura, Yoshio Hayashi, Noriaki Takeda and Hiroyuki Fukui :
鼻過敏症ラット鼻粘膜におけるヒスタミンシグナルとサイトカインシグナルのクロストーク,
日本薬理学会第118回近畿部会, Nov. 2010.
178. Ritsuko 徳永 律子 Oura, Naozumi Ishimaru, Masahiro Hiasa, Kazuma Matsumoto, Yoshio Hayashi and Eiji Tanaka :
Fasを介した末梢T細胞維持機構の破綻による関節リウマチ発症機序の解明,
第69回日本矯正歯科学会, Sep. 2010.
179. Ritsuko 徳永 律子 Oura, Naozumi Ishimaru, Akiko Yamada, Rieko Arakaki, Eiji Tanaka and Yoshio Hayashi :
Fas分子を介したマクロファージによる末梢T細胞の維持機構,
日本病理学会, Vol.99, No.1, 374, Apr. 2010.
180. Kazuma Matsumoto, Naozumi Ishimaru, Rieko Arakaki, Akiko Yamada, Ritsuko 徳永 律子 Oura, Eiji Tanaka and Yoshio Hayashi :
マウス関節炎モデル樹状細胞のRANKL/Fasシグナルを介した免疫抑制効果,
日本病理学会, Vol.99, No.1, 220, Apr. 2010.
181. Naozumi Ishimaru, Akiko Yamada, Rieko Arakaki and Yoshio Hayashi :
シェーグレン症候群における調節性T細胞の役割,
日本病理学会会誌, Vol.99, No.1, 228, Apr. 2010.
182. Akiko Yamada, Naozumi Ishimaru, Rieko Arakaki and Yoshio Hayashi :
Ⅰ型糖尿病モデルマウスにおけるカテプシンL特異的阻害剤を用いた治療効果の検討,
日本病理学会会誌, Vol.99, No.1, 222, Apr. 2010.
183. Kazuma Matsumoto, Naozumi Ishimaru, Rieko Arakaki, Akiko Yamada, Ritsuko 徳永 律子 Oura, Eiji Tanaka and Yoshio Hayashi :
マウス関節炎モデル樹状細胞のRANKL/FASシグナルを介した免疫抑制効果,
日本病理学会会誌, Vol.99, No.1, 220, Apr. 2010.
184. Rieko Arakaki, Naozumi Ishimaru, Akiko Yamada and Yoshio Hayashi :
エストロゲン欠乏依存的に唾液腺に誘導される膵ラ氏島アミロイドポリペプチドの機能とその意義,
日本病理学会会誌, Vol.99, 307, Apr. 2010.
185. 玉田 美咲, Hiroyuki Mizuguchi, Naozumi Ishimaru, Yoshiaki Kitamura, Yoshio Hayashi, Noriaki Takeda and Hiroyuki Fukui :
ラット鼻粘膜におけるヒスタミンとインターロイキン -4 のクロストーク,
日本薬学会第130年会, Mar. 2010.
186. Akiko Yamada, Naozumi Ishimaru, Rieko Arakaki and Yoshio Hayashi :
Therapeutic Analysis by Selective Inhibition of Cathepsin L for Autoimmune Diabetes in NOD Mice,
日本免疫学会総会・学術集会, Dec. 2009.
187. Kazuma Matsumoto, Naozumi Ishimaru, Takashi Izawa, Rieko Arakaki, Ritsuko 徳永 律子 Oura, Eiji Tanaka and Yoshio Hayashi :
Immunoregulatory effect via RANKL and Fas signaling of dendritic cells in immurine autoimmune arthritis models,
日本免疫学会総会・学術集会, Dec. 2009.
188. Ritsuko 徳永 律子 Oura, Naozumi Ishimaru, Akiko Yamada, Rieko Arakaki, Takashi Izawa, Kazuma Matsumoto, Eiji Tanaka and Yoshio Hayashi :
Immune Regulation by Macrophages through cross-talk between Fas and NF-B Signaling,
日本免疫学会総会・学術集会, Dec. 2009.
189. Naozumi Ishimaru, Rieko Arakaki, Akiko Yamada, Yousuke Takahama and Yoshio Hayashi :
In situ patrolling of regulatory T cells is essential for protecting organ-specific autoimmunity,
日本免疫学会総会・学術集会, Dec. 2009.
190. Masayuki Kohashi, Naozumi Ishimaru, Akiko Yamada, Rieko Arakaki and Yoshio Hayashi :
Neonatal exposure to low-dose 2,3,7,8-tetrachlorodibenzo-p-dioxin(TCDD)causes autoimmunity due to the disruption of Tcell tolerance,
2009日本免疫学会総会・学術集会記録, Vol.39, Dec. 2009.
191. Takeo Iwata, Naozumi Ishimaru, Yoshio Hayashi, Noriko Mizusawa and Katsuhiko Yoshimoto :
脂肪組織におけるYKL-40の役割,
第51回歯科基礎医学会学術大会, Sep. 2009.
192. Naozumi Ishimaru, Akiko Yamada, Rieko Arakaki and Yoshio Hayashi :
Local Toleranceの破綻による臓器特異的自己免疫疾患の発症機序,
日本病理学会会誌, Vol.98, No.1, 249, May 2009.
193. Rieko Arakaki, Naozumi Ishimaru, Akiko Yamada and Yoshio Hayashi :
エストロゲン欠乏によって唾液腺に誘導される樹状細胞の同定とその機能,
日本病理学会会誌, Vol.98, No.1, 365, May 2009.
194. Akiko Yamada, Naozumi Ishimaru, Rieko Arakaki and Yoshio Hayashi :
Ⅰ型糖尿病マウスにおけるカテプシンLを介した治療学的解析,
日本病理学会会誌, Vol.98, No.1, 240, May 2009.
195. Takashi Izawa, Naozumi Ishimaru, Rieko Arakaki, Ritsuko 徳永 律子 Oura, Eiji Tanaka and Yoshio Hayashi :
Analysis of RANKL and Fas signaling through NF-kB in dendritic cell activation in murine autoimmune arthritis models,
Proceedings of the Japanese Society for Immunology, Vol.38, 176, Dec. 2008.
196. Rieko Arakaki, Naozumi Ishimaru, Akiko Yamada and Yoshio Hayashi :
Identification and functional analysis of CD11c+B220+ dendritic cells induced by estrogen deficiency in salivary glands .,
第38回日本免疫学会総会・学術集会, Vol.38, 97, Dec. 2008.
197. Naozumi Ishimaru, Kohashi Masayuki, Akiko Yamada, Rieko Arakaki and Yoshio Hayashi :
Neonatal exposure to low-dose 2,3,7,8-tetrachlorodibenzo-p-dioxin(TCDD)causes autoimmunity due to the disruption of T cell tolerance,
第38回日本免疫学会総会・学術集会, Vol.38, 97, Dec. 2008.
198. Akiko Yamada, Naozumi Ishimaru, Rieko Arakaki and Yoshio Hayashi :
Therapeutic analysis for autoimmune diabetes in NOD mice using specific inhibitor for cathepsin L,
第38回日本免疫学会総会・学術集会, Vol.38, 93, Dec. 2008.
199. Hiroyoshi Hosokawa, Kazuhito Satomura, Keiko Kudoh, Seiko Tatehara, Reiko Tokuyama, Hideyuki Takano, Masaru Nagayama, Naozumi Ishimaru and Yoshio Hayashi :
頬粘膜に発生した血管筋腫の1例,
Journal of The Japanese Stomatological Society, Vol.57, No.3, 348, Jul. 2008.
200. Hiroyoshi Hosokawa, Kazuhito Satomura, Keiko Kudoh, Seiko Tatehara, Reiko Tokuyama, 高野 栄之, Naozumi Ishimaru, Yoshio Hayashi and Masaru Nagayama :
頬粘膜に発生した血管筋腫の1例,
Journal of The Japanese Stomatological Society, Vol.57, No.3, 348, Jul. 2008.
201. Hoang Nam Tran, Takashi Sakai, Salah M. El-Sayed, Li Liu, Rika Sakai, Naozumi Ishimaru, Yoshio Hayashi, Ryuji Kaji and Kiyoshi Fukui :
新規アポトーシス制御分子ヌクリングはNF-κB の制御に関与する,
第49回日本生化学会中国四国支部例会, May 2008.
202. Naozumi Ishimaru and Yoshio Hayashi :
自己免疫病と性差,
第97回日本病理学会総会, Vol.97, No.1, 170, May 2008.
203. Rieko Arakaki, Naozumi Ishimaru, Akiko Yamada and Yoshio Hayashi :
エストロゲン欠乏による外分泌腺上皮クラスⅡ発現の誘導メカニズム,
第97回日本病理学会総会, Vol.97, No.1, 322, May 2008.
204. Akiko Yamada, Naozumi Ishimaru, Rieko Arakaki and Yoshio Hayashi :
Ⅰ型糖尿病モデルマウスにおけるカテプシンL阻害剤を用いた治療学的解析,
第97回日本病理学会総会, Vol.97, No.1, 266, May 2008.
205. Naozumi Ishimaru :
自己免疫疾患におけるT細胞抑制機構,
第62回日本口腔科学会学術集会, 101, Apr. 2008.
206. Naozumi Ishimaru :
自己免疫疾患におけるT細胞の抑制機構,
第6回口腔医学フロンティア, Feb. 2008.
207. Takashi Sakai, HoangNam Tran, Li Liu, Xichuan Teng, Naozumi Ishimaru, Rika Sakai, Nobuya Sano, Ryuji Kaji, Yoshio Hayashi and Kiyoshi Fukui :
Nucling is essential for the maintenance of Kupffer cells related to tumorgenesis in liver,
The 30th Annual Meetings of the Molecular Biology Society of Japan/The 80th Annual Meeting of the Japanese Biochemical Society, Dec. 2007.
208. Naozumi Ishimaru :
自己免疫疾患におけるNF-kBシグナルを介したT細胞の抑制機構,
日本病理学会秋期総会A演説, Dec. 2007.
209. Naozumi Ishimaru, Rieko Arakaki and Yoshio Hayashi :
IFN-γ-producing epithelial cells links autoimmune exocrinopathy resembling SS in RbAp48 TG mice,
第37回日本免疫学会総会・学術集会, Vol.37, 263, Nov. 2007.
210. Rieko Arakaki, Naozumi Ishimaru, Akiko Yamada and Yoshio Hayashi :
Role of estrogen deficiency for aberrant MHC class 2 expression in the exocring gland cells,
第37回日本免疫学会総会・学術集会, Vol.37, 265, Nov. 2007.
211. Akiko Yamada, Naozumi Ishimaru, Rieko Arakaki and Yoshio Hayashi :
T cell functions with aging in NF-kB1-deficient mice,
第37回日本免疫学会総会・学術集会, Vol.37, 174, Nov. 2007.
212. Takashi Izawa, Naozumi Ishimaru, Masayuki Kohashi, Rieko Arakaki and Yoshio Hayashi :
Crosstalk between RANKL and Fas signaling in dendritic cells controls immune tolerance,
第37回日本免疫学会総会・学術集会 ワークショップ, Vol.37, Nov. 2007.
213. Miho Okuno, Naozumi Ishimaru, Takashi Izawa, Rieko Arakaki, Akiko Yamada and Yoshio Hayashi :
Analysis of NF-kB in T cell activation in murine autoimmune model,
第37回日本免疫学会総会・学術集会, Vol.37, 119, Nov. 2007.
214. Masayuki Kohashi, Naozumi Ishimaru, Akiko Yamada, Rieko Arakaki, Jun Kanno and Yoshio Hayashi :
The effect of TCDD administration on murine model for Sjogren's syndrome,
第37回日本免疫学会総会・学術集会, Vol.37, 116, Nov. 2007.
215. Naozumi Ishimaru :
唾液腺アポトーシスと自己免疫,
日本口腔病理学会総会シンポジウム, Aug. 2007.
216. Takashi Izawa, Naozumi Ishimaru, Rieko Arakaki and Yoshio Hayashi :
関節リウマチモデルMRL/lprマウス樹状細胞の機能解析,
第6回四国免疫フォーラム 一般演題, Jul. 2007.
217. Hiroyoshi Hosokawa, Kazuhito Satomura, Yukihiro Momota, Keiko Kudoh, Seiko Tatehara, Reiko Tokuyama, Hideyuki Takano, Naozumi Ishimaru, Yoshio Hayashi, Masaru Nagayama and 第17回日本口腔粘膜学会 :
口腔白板症の臨床病理学的検討,
第17回日本口腔粘膜学会 2007.7.5∼7.6,東京, Jul. 2007.
218. Takashi Sakai, Li Liu, Xichuan Teng, Naozumi Ishimaru, Rika Sakai, Nobuya Sano, Ryuji Kaji, Hoang Nam Tran, Yoshio Hayashi and Kiyoshi Fukui :
新規アポトーシス制御分子ヌクリングの肝癌発症機構における役割の解明,
第48回日本生化学会中国四国支部例会, May 2007.
219. Kohashi Masayuki, Rieko Arakaki, Naozumi Ishimaru and Yoshio Hayashi :
シェーグレン症候群モデルマウスにおけるレバミピドの病態抑制効果,
第96回日本病理学会総会, Vol.96, No.1, 295, Mar. 2007.
220. Rieko Arakaki, Naozumi Ishimaru, Kohashi Masayuki and Yoshio Hayashi :
シェーグレン症候群類似RbAp48遺伝子導入マウスにおける病態形成の解析,
第96回日本病理学会総会, Vol.96, No.1, 295, Mar. 2007.
221. Rieko Arakaki, Naozumi Ishimaru, Masayuki Kohashi and Yoshio Hayashi :
シェーグレン症候群類似RbAp48遺伝子導入マウスにおける病態形成の解析,
日本病理学会会誌, Vol.96, No.1, Mar. 2007.
222. Masayuki Kohashi, Rieko Arakaki, Naozumi Ishimaru and Yoshio Hayashi :
シェーグレン症候群モデルマウスにおけるレバミピドの病態抑制効果,
日本病理学会会誌, Vol.96, No.1, Mar. 2007.
223. Naozumi Ishimaru, 高木 篤也, 菅野 純 and Yoshio Hayashi :
新生仔マウスへのダイオキシン投与による免疫系への影響,
日本病理学会会誌, Vol.96, No.1, Mar. 2007.
224. Naozumi Ishimaru, 高木 篤也, 菅野 純 and Yoshio Hayashi :
新生仔マウスへのダイオキシン投与による免疫系への影響,
第96回日本病理学会総会, Vol.96, No.1, 224, Mar. 2007.
225. Takashi Izawa, Naozumi Ishimaru, Rieko Arakaki, Keiji Moriyama and Yoshio Hayashi :
Immunoregulatory role of RANKL-stimulated dendritic cells on autoimmune arthritis in MRL/lpr mice,
第36回日本免疫学会総会・学術集会 ワークショップ, Vol.36, 284, Dec. 2006.
226. Naozumi Ishimaru, Masayuki Kohashi, Rieko Arakaki, Hidehiro Kishimoto and Yoshio Hayashi :
NF-κB2 pathway in T cell activation for autoimmunity,
日本免疫学会総会・学術集会記録, Vol.36, Dec. 2006.
227. Masayuki Kohashi, Naozumi Ishimaru, Rieko Arakaki and Yoshio Hayashi :
Effect of rebamipide administration on Sjogren's syndrome mouse model,
日本免疫学会総会・学術集会記録, Vol.36, Dec. 2006.
228. Rieko Arakaki, Naozumi Ishimaru and Yoshio Hayashi :
Development of exocrinopathy resembling Sjogren's syndrome in RbAp48 transgenic mice,
日本免疫学会総会・学術集会記録, Vol.36, Dec. 2006.
229. Naozumi Ishimaru and Yoshio Hayashi :
NF-kBシグナルを介した自己免疫疾患の発症機序,
第54回NPO法人日本口腔科学会, Nov. 2006.
230. 大嶋 淳, Takashi Izawa, Naozumi Ishimaru, Yoshio Hayashi and Keiji Moriyama :
関節炎モデルマウスを用いた樹状細胞移入による関節リウマチ病態の修飾,
第65回日本矯正歯科学会大会 学術展示, 217, Sep. 2006.
231. Naozumi Ishimaru, Keisuke Izumi and Yoshio Hayashi :
LECラットに発生する炎症性腸疾患の解析,
第3回日本病理学会カンファレンス ポスター発表, Aug. 2006.
232. Yoshio Hayashi, Naozumi Ishimaru and Nobuhiko Katunuma :
Cathepsin L-inhibitor Prevents Proinsulin Peptide Processing and Autoimmune Diabetes in Nonobetic(NOD)Mice,
Satellite Meeting of the 20th IUBMB International Congress and 11th FAOBMB Congress, Jun. 2006.
233. Naozumi Ishimaru and Yoshio Hayashi :
In Vivo Role of NF-κB-inducing Kinase for T Cell Activation,
Satellite Meeting of the 20th IUBMB International Congress and 11th FAOBMB Congress, Jun. 2006.
234. Rieko Arakaki, Naozumi Ishimaru and Yoshio Hayashi :
臓器特異的アポトーシスと自己免疫,
第5回四国免疫フォーラム 一般演題, Jun. 2006.
235. Naozumi Ishimaru, Hidehiro Kishimoto, Yoshio Hayashi and Sprent Jonathan :
T細胞活性化機構におけるNF-kB2経路の役割,
第16回Kyoto T Cell Conference(KTCC) ワークショップ, Jun. 2006.
236. Naozumi Ishimaru, Keisuke Izumi and Yoshio Hayashi :
LECラットに発生する炎症性腸疾患の解析,
第16回LECラット研究会大会, May 2006.
237. Fumie Omotehara, Naozumi Ishimaru, Rieko Arakaki and Yoshio Hayashi :
シェーグレン症候群加齢モデルマウスにおける間質性肺病変の解析,
第95回日本病理学会総会 一般口演, Vol.95, No.1, 211, May 2006.
238. Naozumi Ishimaru, Rieko Arakaki, Fumie Omotehara and Yoshio Hayashi :
NF-kBシグナルを介した自己免疫疾患の発症機序,
第95回日本病理学会総会 一般口演, Vol.95, No.1, 211, May 2006.
239. Katsushi Miyazaki, Noriaki Takeda, Naozumi Ishimaru and Yoshio Hayashi :
原発性シェーグレン症候群における自己抗原α-フォドリンの生体内での役割の解析,
第107回日本耳鼻咽喉科学会総会, May 2006.
240. Naozumi Ishimaru, Hidehiro Kishimoto, Jonathan Sprent and Yoshio Hayashi :
Immunoregulation by NF-kB for T cell activation in autoimmune disease,
日本免役学会総会·学術集会記録, Vol.35, 275, Dec. 2005.
241. Naozumi Ishimaru, Hidehiro Kishimoto, Jonathan Sprent and Yoshio Hayashi :
Immunoregulation by NF-kB for T cell activation in autoimmune disease,
第35回日本免疫学会総会・学術集会 ワークショップ, Vol.35, 275, Dec. 2005.
242. Takashi Izawa, Naozumi Ishimaru, Fumie Omotehara, Rieko Arakaki, 大嶋 淳, Keiji Moriyama and Yoshio Hayashi :
RANKL刺激活性化DCを介したMRL/lprマウス関節炎の病態修飾,
第35回日本免疫学会総会・学術集会 ワークショップ, Vol.35, 249, Dec. 2005.
243. Megumi Watanabe, Naozumi Ishimaru, Rieko Arakaki, Fumie Omotehara and Yoshio Hayashi :
Niアレルギーにおける樹状細胞及びT細胞の活性化機構,
日本免役学会総会·学術集会記録, Vol.35, 140, Dec. 2005.
244. Megumi Watanabe, Naozumi Ishimaru, Rieko Arakaki, Fumie Omotehara and Yoshio Hayashi :
Niアレルギーにおける樹状細胞及びT細胞の活性化機構,
第35回日本免疫学会総会・学術集会 ワークショップ, Vol.35, 140, Dec. 2005.
245. Fumie Omotehara, Naozumi Ishimaru, Rieko Arakaki and Yoshio Hayashi :
シェーグレン症候群加齢モデルマウスにおける間質性肺病変の解析,
日本免役学会総会·学術集会記録, Vol.35, 36, Dec. 2005.
246. 小橋 真之, Naozumi Ishimaru, Rieko Arakaki and Yoshio Hayashi :
シェーグレン症候群モデルマウスにおけるレバミピドの治療効果の検討,
日本免役学会総会·学術集会記録, Vol.35, 33, Dec. 2005.
247. Fumie Omotehara, Naozumi Ishimaru, Rieko Arakaki and Yoshio Hayashi :
シェーグレン症候群加齢モデルマウスにおける間質性肺病変の解析,
第35回日本免疫学会総会・学術集会 ワークショップ, Vol.35, 36, Dec. 2005.
248. 小橋 真之, Naozumi Ishimaru, Rieko Arakaki and Yoshio Hayashi :
シェーグレン症候群モデルマウスにおけるレバミピドの治療効果の検討,
第35回日本免疫学会総会・学術集会 ワークショップ, Vol.35, 33, Dec. 2005.
249. Naozumi Ishimaru :
自己免疫疾患におけるNF-kBを介したT細胞の活性化機構,
Journal of Oral Biosciences, Vol.47, 69, Sep. 2005.
250. Naozumi Ishimaru :
自己免疫疾患におけるNF-kBを介したT 細胞の活性化機構,
第47回歯科基礎医学会学術大会ならびに総会 シンポジウム, Vol.47, 69, Sep. 2005.
251. 大嶋 淳, Takashi Izawa, Naozumi Ishimaru, Fumie Omotehara, Rieko Arakaki, Keiji Moriyama and Yoshio Hayashi :
樹状細胞移入によるMRL/lprマウス関節リウマチ病態の修飾,
第2回日本病理学会カンファレンス ポスター発表, 46, Jul. 2005.
252. Fumie Omotehara, Naozumi Ishimaru, Rieko Arakaki and Yoshio Hayashi :
RbAp48トランスジェニックマウスを用いたシェーグレン症候群新規モデルの作成,
第2回日本病理学会カンファレンス ポスター発表, 48, Jul. 2005.
253. Naozumi Ishimaru and Yoshio Hayashi :
自己免疫疾患におけるNF-kBを介したT細胞活性化機構の解析,
第二回日本病理学会カンファレンス ポスター発表, 38, Jul. 2005.
254. Naozumi Ishimaru and Yoshio Hayashi :
T細胞活性化機構におけるRelBの役割,
第4回四国免疫フォーラム, Jun. 2005.
255. Naozumi Ishimaru :
自己免疫疾患におけるNF-kBを介したT細胞活性化機構の解析,
四国歯学会第29回例会・第24回総会 帰朝講演, Vol.18, No.2, Jun. 2005.
(Tokushima University Institutional Repository: 263)
256. Naozumi Ishimaru, Rieko Arakaki, Fumie Omotehara and Yoshio Hayashi :
自己免疫疾患におけるNF-kBを介したT細胞活性化機構の解析,
第94回日本病理学会総会 一般口演, Vol.94, No.1, 224, Apr. 2005.
257. Rieko Arakaki, Naozumi Ishimaru, Fumie Omotehara and Yoshio Hayashi :
RbAp48遺伝子導入マウスにみられるシェーグレン症候群類似病変の解析,
第94回日本病理学会総会 一般口演, Vol.94, No.1, 206, Apr. 2005.
258. Fumie Omotehara, Naozumi Ishimaru, Rieko Arakaki, 大嶋 淳 and Yoshio Hayashi :
シェーグレン症候群における自己抗原120kDa α-フォドリンの意義,
第94回日本病理学会総会 一般口演, Vol.94, No.1, 206, Apr. 2005.
259. Jun Oshima, Naozumi Ishimaru, Rieko Arakaki, Fumie Omotehara and Yoshio Hayashi :
RANKL刺激樹状細胞移入によるMRL/lprマウス関節リウマチ病変の解析,
第94回日本病理学会総会 一般口演, Vol.94, No.1, 197, Apr. 2005.
260. Takashi Izawa, Naozumi Ishimaru, Rieko Arakaki and Yoshio Hayashi :
RANKL刺激樹状細胞移入によるMRL/lprマウス自己免疫性関節炎の病態修飾,
第33回日本免疫学会総会・学術集会 ワークショップ, Dec. 2003.
261. 日比 弓紀子, Kenji Fujisawa, Tetsuya Yuasa, Naozumi Ishimaru and Masaru Nagayama :
歯肉増殖を伴ったSturge-Weber症候群の1例,
第49回日本口腔科学会中国・四国地方部会, 2001.
262. Yoshiko Noda, Yukihiro Momota, Kazuhito Satomura, 鎌田 伸之, Naozumi Ishimaru and Masaru Nagayama :
上顎洞に発症したアスペルギルス症の1例 : 血清学的検査の有用性についての考察,
第45回日本口腔外科学会総会, Oct. 2000.
263. Yukihiro Momota, Yoshiko Noda, Kazuhito Satomura, Nobuyuki Kamata, Masaru Nagayama and Naozumi Ishimaru :
上顎洞に発症したアスペルギルス症の2例-PCR法を用いた遺伝子診断-,
第45回日本口腔外科学会総会, 2000.

Et cetera, Workshop:

1. Natsumi Fujiwara, Wenhua Shao, Kaya Yoshida, Rieko Arakaki, Kazumi Ozaki, Naozumi Ishimaru and Yasusei Kudo :
Fusobacterium nucleatumが与える口腔癌細胞への影響,
第38回 分子病理学研究会 淡路島シンポジウム(兵庫県) 2019年7月19-20日, Jul. 2019.
2. Takashi Izawa, Rieko Arakaki, Eiji Tanaka and Naozumi Ishimaru :
Crosstalk between cytokine RANKL and AhR signaling in osteoclasts controls bone homeostasis,
Gordon Research Seminar; "Bones and Teeth" Translating Mechanisms of Bone Formation and Repair, Jan. 2018.
3. S. Afroz, Iwasa Takuma, Oshima Masamitsu, Rieko Arakaki, Miho Inoue, Naozumi Ishimaru and Yoshizo Matsuka :
Cytokine release from satellite glial cells of trigeminal ganglia,
Tokushima University Bioscience Retreat, Sep. 2017.
4. Keiko Aota, Yoshiko Yamamura, Katsumi Motegi, Naozumi Ishimaru and Masayuki Azuma :
シェーグレン症候群患者に対するセファランチンの有効性に関する臨床病理学的研究,
Shikoku Dental Research, Mar. 2012.
5. Naozumi Ishimaru and Yoshio Hayashi :
臓器特異的アポトーシスとシェーグレン症候群,
第15回日本シェーグレン症候群研究会, Sep. 2006.

Report:

1. Jonathan Sprent, Onur Boyman, Jea Hoe Cho, Naozumi Ishimaru, Hidehiro Kishimoto, M Kovar, DC Lenz, MP Rubinstein and X Shen :
The Thymus and T-Cell Specificity,
The Scripps Research Institute Scientific Report, Vol.30, 141-142, Sep. 2005.

Grants-in-Aid for Scientific Research (KAKEN Grants Database @ NII.ac.jp)

  • Establishment of novel oral cancer stem cell model mimicking human oral cancer by reprogramming and insertion of gene mutation (Project/Area Number: 19H03853 )
  • Analysis of Pathogenesis of Autoimmunity through Communication between Organs (Project/Area Number: 19H01070 )
  • Molecular Mechanism of Autoimmune Germinal Center Reaction and a New Therapeutic Strategy for Autoimmunity (Project/Area Number: 18K19648 )
  • Study on the generation of oral cancer stem cell and analysis of its nature (Project/Area Number: 17K19760 )
  • 歯髄幹細胞由来液性因子による口腔乾燥症の新規治療法の開発 (Project/Area Number: 17H04404 )
  • 染色体パッセンジャー複合体タンパクの分解とその破綻による口腔発癌機構の解明と制御 (Project/Area Number: 16H05542 )
  • Analysis of autoimmunity caused by environmental factors~New pathogenesis of autoimmune disease~ (Project/Area Number: 16H02690 )
  • Explore for master regulator of EMT in oral cancer (Project/Area Number: 15K15740 )
  • Development of diagnostic techniques specific for Sjogren's syndrome by estrogen-related molecules (Project/Area Number: 15K15676 )
  • Analysis of molecular mechanisms of sensitization phase to develop effective treatments against metal allergy (Project/Area Number: 15H05028 )
  • 新規バイオマーカーを用いたシェーグレン症候群の確定診断法の開発 (Project/Area Number: 22659342 )
  • The analysis of Ni allergy development and the therapeutic strategy in prosthodontics (Project/Area Number: 21390518 )
  • 自己免疫疾患における標的臓器と免疫ネットワークの解明と新規治療法の開発 (Project/Area Number: 21390503 )
  • Immunotherapeutic analysis using newly established murine models for Sjogren' s syndrome (Project/Area Number: 21249090 )
  • Effect of estrogen deficiency on the development of autoimmune diseases (Project/Area Number: 20390479 )
  • 調節性T細胞を制御する新規免疫調節機構の解明 (Project/Area Number: 19659491 )
  • Effect of Sex Hormone on the Development of Autoimmune Diseases (Project/Area Number: 18390498 )
  • 自己免疫疾患におけるNF-κBを介したT細胞活性化機構の解析 (Project/Area Number: 17689049 )
  • Molecular analysis of pathogenesis on Sjogren's syndrome and its application of new diagnosis and therapy (Project/Area Number: 17109016 )
  • Fasリガンド分子制御によるシェーグレン症候群治療法の研究開発 (Project/Area Number: 15659094 )
  • 自己免疫疾患におけるエストロジェンを介したアポトーシス調節機構の解析 (Project/Area Number: 12771086 )
  • 自己免疫疾患老化モデルにおけるp16の解析 (Project/Area Number: 12671826 )
  • Search by Researcher Number (60314879)