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Tokushima University > University Hospital > Clinical Division > Department of General Dentistry > Conservative Dentistry >
Tokushima University > Faculty of Dentistry > Course in Dentistry > Basic Oral Sciences > Preventive Dentistry >

Research Activity

Field of Study

Preventive Dentistry

Subject of Study

Systemic Infections Caused by Oral Indigenous Bacteria; Pathogenesis and Prevention, Search for Molecular Mimics That Inhibit Bacterial Adherence, Clinical Epidemiological Studies for Prevention and Treatment of Dental Diseases., Immune Network/Immunological Memory and Maternal Immunity/Mucosal Immunity

Book / Paper

Book:

1.Hiro-O Ito :
第4章 齲蝕とその予防, 新予防歯科学 第4版, p. 73-86, 米満正美ほか編, 医歯薬出版社, 東京, 2010年4月1日.(分担),
Apr. 2010.
2.Hiro-O Ito and 末高 武彦ほか編 :
新口腔保健学 第1版,
医歯薬出版社, Tokyo, 2009.
3.吉山 昌宏, Hiro-O Ito and 十河 基文 :
プラークコントロール法の現状と課題, MI 時代の歯科知識-プラークコントロール・サイエンス&プラクティス,
永末書店, Kyoto, 2009.
4.Kiyoshi Nokihara, Hiro-O Ito, Sakiko Soutome, Takafumi Ohyama, Shizue Yamamoto, Tadashi Yasuhara and Masakazu Inoue :
Application of Combinatorial Peptide Libraries to Prevention of Infectious Endocarditis, as an Example for Infection Control,
The Japanese Peptide Society, Osaka, Mar. 2003.
5.Y Okada, Hiro-O Ito, K Kitada and M Inoue :
Infectivity of nutritionally variant streptococci: capacity of endocarditis induction and extracellular matrix binding. p.653-656, In : Martin, D. R. and Tagg, J. R. (Eds.) Streptococci and streptococcal diseases.,
Proceedings of the XIV Lancefield International, Priura, New Zealand, 2000.

Academic Paper (Judged Full Paper):

1.Naofumi Tamaki, 松尾 亮, 水野 昭彦, 正木 文浩, 中川 徹, 鈴木 雅博, Makoto Fukui, 谷口 隆司, 三宅 達郎 and Hiro-O Ito :
歯肉溝液中の炎症関連バイオマーカーと糖尿病・腎機能マーカーとの関連性,
Journal of Dental Health, Vol.66, No.3, 316-321, 2016.
2.Naofumi Tamaki, Rita Cristina Orihuela Campos, Makoto Fukui and Hiro-O Ito :
Hydrogen-Rich Water Intake Accelerates Oral Palatal Wound Healing via Activation of the Nrf2/Antioxidant Defense Pathways in a Rat Model.,
Oxidative Medicine and Cellular Longevity, Vol.2016, 5679040, 2016.
(Tokushima University Institutional Repository: 109746,   DOI: 10.1155/2016/5679040,   PubMed: 26798423)
3.S Hayashi, Hirotsugu Yamada, Makoto Fukui, Hiro-O Ito and Masataka Sata :
Correlation between arteriosclerosis and periodontal condition assessed by lactoferrin and [alpha]1-antitrypsin levels in gingival crevicular fluid.,
International Heart Journal, Vol.56, No.6, 639-643, 2015.
(DOI: 10.1536/ihj.15-218,   PubMed: 26549390,   Thomson Reuters: Web of Science™)
4.Naofumi Tamaki, Fumihiko Yoshino, Makoto Fukui, Hideaki Hayashida, Ayaka Yoshida, Masayasu Kitamura, Takahiro Iwasaki, Reiko Furugen, Koji Kawasaki, Mio Nakazato, Takahiro Maeda, Susumu Kokeguchi, Tatsuo Yamamoto, Chang-Il Masaichi Lee, Hiro-O Ito and Toshiyuki Saito :
Relationship among salivary antioxidant activity, cytokines and periodontitis: the Nagasaki Island study.,
Journal of Clinical Periodontology, Vol.42, No.8, 711-718, 2015.
(DOI: 10.1111/jcpe.12438,   PubMed: 26227009,   Thomson Reuters: Web of Science™,   Elsevier: Scopus)
5.Rita Cristina Orihuela Campos, Naofumi Tamaki, Rie Mukai, Makoto Fukui, Kaname Miki, Junji Terao and Hiro-O Ito :
Biological impacts of resveratrol, quercetin, and N-acetylcysteine on oxidative stress in human gingival fibroblasts.,
Journal of Clinical Biochemistry and Nutrition, Vol.56, No.3, 220-227, 2015.
(DOI: 10.3164/jcbn.14-129,   PubMed: 26060353,   Thomson Reuters: Web of Science™,   Elsevier: Scopus)
6.Naofumi Tamaki, Rita Cristina Orihuela Campos, Yuji Inagaki, Makoto Fukui, Toshihiko Nagata and Hiro-O Ito :
Resveratrol improves oxidative stress and prevents the progression of periodontitis via the activation of the Sirt1/AMPK and the Nrf2/antioxidant defense pathways in a rat periodontitis model.,
Free Radical Biology and Medicine, Vol.75, 222-229, 2014.
(DOI: 10.1016/j.freeradbiomed.2014.07.034,   PubMed: 25091897)
7.Naofumi Tamaki, H Hayashida, Makoto Fukui, M Kitamura, K Kawasaki, M Nakazato, T Maeda, T Saito and Hiro-O Ito :
Oxidative stress and antibody levels to periodontal bacteria in adults: the Nagasaki Islands study.,
Oral Diseases, Vol.20, No.3, 49-56, 2014.
(DOI: 10.1111/odi.12127,   PubMed: 23679350,   CiNii: 120005597346,   Thomson Reuters: Web of Science™,   Elsevier: Scopus)
8.Yoshikazu Fukumoto, Masumi Horibe, Yuji Inagaki, Keiji Oishi, Naofumi Tamaki, Hiro-O Ito and Toshihiko Nagata :
Association of gingival recession and other factors with the presence of dentin hypersensitivity.,
Odontology, 2013.
(DOI: 10.1007/s10266-012-0099-5,   PubMed: 23283584)
9.Masaki GOTO, Agnieszka Wilk, Kosuke Kataoka, Shirish Chodankar, Nobutake Tamai, Makoto Fukui, Joachim Kohlbrecher, Hiro-O Ito and Hitoshi Matsuki :
Study on the Subgel-Phase Formation Using an Asymmetric Phospholipid Bilayer Membrane by High-Pressure Fluorometry,
Langmuir, Vol.28, No.33, 12191-12198, 2012.
(DOI: 10.1021/la3020173,   PubMed: 22823885,   Thomson Reuters: Web of Science™)
10.Tselmeg Baatarjav, Kosuke Kataoka, Rebekah S. Gilbert, Yutaka Terao, Makoto Fukui, Masaki GOTO, Shigetada Kawabata, Masato Yamamoto, Kohtaro Fujihashi and Hiro-O Ito :
Mucosal immune features to phosphorylcholine by nasal Flt3 ligand cDNA-based vaccination,
Vaccine, Vol.29, No.34, 5747-5757, 2011.
(DOI: 10.1016/j.vaccine.2011.05.097,   PubMed: 21683111)
11.Kosuke Kataoka, Kohtaro Fujihashi, Keita Oma, Yoshiko Fukuyama, K Susan Hollingshead, Shinichi Sekine, Shigetada Kawabata, Hiro-O Ito, E David Briles and Kazunori Oishi :
Nasal Dendritic Cell Targeting Flt3 Ligand As A Safe Adjuvant Elicits Effective Protection Against Fatal Pneumococcal Pneumonia.,
Infection and Immunity, Vol.79, No.7, 2819-2828, 2011.
(DOI: 10.1128/IAI.01360-10,   PubMed: 21536790)
12.Makoto Fukui, Daisuke Hinode, Masaaki Yokoyama, Masami Yoshioka, Kosuke Kataoka and Hiro-O Ito :
Levels of salivary stress markers in patients with anxiety about halitosis,
Archives of Oral Biology, Vol.55, No.11, 842-847, 2010.
(DOI: 10.1016/j.archoralbio.2010.07.014,   PubMed: 20807658,   Thomson Reuters: Web of Science™)
13.Etsuhisa Takahashi, Kosuke Kataoka, Kazuyuki Fujii, Junji Chida, Dai Mizuno, Makoto Fukui, Hiro-O Ito, Kohtaro Fujihashi and Hiroshi Kido :
Attenuation of inducible respiratory immune responses by oseltamivir treatment in mice infected with influenza A virus.,
Microbes and Infection, Vol.12, No.10, 778-783, 2010.
(DOI: 10.1016/j.micinf.2010.04.013,   PubMed: 20452454)
14.Hidetaka Nakagaki, Shinichi Sekine, Yutaka Terao, Masahiro Toe, Muneo Tanaka, Hiro-O Ito, Shigetada Kawabata, Satoshi Shizukuishi, Kohtaro Fujihashi and Kosuke Kataoka :
Fusobacterium nucleatum envelope protein FomA is immunogenic and binds to the salivary statherin-derived peptide.,
Infection and Immunity, Vol.78, No.3, 1185-1192, 2010.
(DOI: 10.1128/IAI.01224-09,   PubMed: 20008529)
15.Masaaki Yokoyama, Makoto Fukui, Kaname Masuda, Natsuko Takamatsu, Jurou Okada, 裕光 武部, Kosuke Kataoka and Hiro-O Ito :
リアルタイム定量PCR(qPCR)法による唾液中の総細菌数の測定 口腔清潔度の指標としての試み,
Journal of Dental Health, Vol.59, No.3, 183-189, 2009.
(CiNii: 110008460531)
16.Masaaki Yokoyama, Daisuke Hinode, Masami Yoshioka, Makoto Fukui, Shin-ichi Tanabe, Daniel Grenier and Hiro-O Ito :
Relationship between Campylobacter rectus and periodontal status during pregnancy.,
Oral Microbiology and Immunology, Vol.23, No.1, 55-59, 2008.
(DOI: 10.1111/j.1399-302X.2007.00391.x,   PubMed: 18173799,   Thomson Reuters: Web of Science™)
17.Mariko Naito, Yoshimi Suzukamo, Hiro-O Ito and Takeo Nakayama :
Development of the Japanese version of the Oral Impacts on Daily Performance (OIDP) scale: a pilot study.,
Journal of Oral Science, Vol.49, No.4, 259-264, 2007.
(DOI: 10.2334/josnusd.49.259,   PubMed: 18195507)
18.N Tanaka, S Fukuyama, T Fukuiwa, M Kawabata, Y Sagara, Hiro-O Ito, Y Miwa, T Nagatake, H Kiyono and Y Kurono :
Intranasal immunization with phosphorylcholine induces antigen specific mucosal and systemic immune responses in mice.,
Vaccine, Vol.25, No.14, 2680-2687, 2007.
(DOI: 10.1016/j.vaccine.2006.10.014,   PubMed: 17270319)
19.E Nagata, H Okayama, Hiro-O Ito, Y Yamashita, M Inoue and T Oho :
Serotype-specific polysaccharide of Streptococcus mutans contributes to infectivity in endocarditis.,
Oral Microbiology and Immunology, Vol.21, No.6, 420-423, 2006.
(DOI: 10.1111/j.1399-302X.2006.00317.x,   PubMed: 17064403)
20.Hiro-O Ito, K. Nokihara, S. Soutome and T. Ohyama :
Screening of peptides that inhibit bacterial binding to fibronectin using combinatorial peptide libraries.,
International Journal of Peptide Research and Therapeutics, Vol.12, No.3, 275-281, 2006.
(DOI: 10.1007/s10989-006-9030-7,   Thomson Reuters: Web of Science™,   Elsevier: Scopus)
21.E Nagata, H Okayama, Hiro-O Ito, I Semba, M Inoue and T Oho :
Experimental infective endocarditis induced by human supragingival dental plaque in rats.,
European Journal of Oral Sciences, Vol.113, No.6, 499-504, 2005.
(DOI: 10.1111/j.1600-0722.2005.00258.x,   PubMed: 16324140)
22.Y Miwa, Hiro-O Ito, M Inoue and T Oho :
Induction of immune response to Streptococcus pneumoniae by administration of oral viridans streptococci via phosphorylcholine determinant.,
FEMS Immunology and Medical Microbiology, Vol.43, No.3, 441-448, 2005.
(DOI: 10.1016/j.femsim.2004.11.001,   PubMed: 15708320)
23.Hidehito Okayama, Emi Nagata, Hiro-O Ito, Takahiko Oho and Masakazu Inoue :
Experimental Abscess Formation Caused by Human Dental Plaque,
Microbiology and Immunology, Vol.49, No.5, 399-405, 2005.
(PubMed: 15905601,   Thomson Reuters: Web of Science™)
24.Hiro-O Ito, Sakiko Soutome, Kiyoshi Nokihara and Masakazu Inoue :
Identification and characterization of bacterial-binding property in the type III repeat domain of fibronectin,
Biochemical and Biophysical Research Communications, Vol.320, No.2, 347-353, 2004.
(DOI: 10.1016/j.bbrc.2004.05.170,   PubMed: 15219833,   Thomson Reuters: Web of Science™)
25.水流 和徳, Hiro-O Ito, 富田 浩一, 瀬戸口 尚志, 門川 明彦, 川島 清美, 西原 一秀, 瀬戸上 康子, 重田 浩樹, 佐藤 強志, 石神 哲郎 and 長岡 英一 :
本学歯学部における OSCE トライアルの実施方法について,
The Journal of Japanese Dental Education Association, Vol.19, No.1, 160-169, 2003.
(CiNii: 10011830308)
26.石川 久美子, 古市 保志, Hiro-O Ito, 四元 幸治, 下津 昭洋, 山下 皓三, 児島 正明 and 和泉 雄一 :
歯周病罹患状況と臨床検査値および歯周病原性細菌に対する血清抗体価の変化とその関連,
歯周組織,臨床検査値および血清抗体価に関する3年間の追跡調査, 394-401, 2003.
27.Hiro-O Ito, Sakiko Soutome and Masakazu Inoue :
Inhibition of fibronectin binding of some bacterial cells by subtle pH increase within the physiological range,
Journal of Microbiological Methods, Vol.55, No.1, 29-34, 2003.
(DOI: 10.1016/S0167-7012(03)00111-8,   PubMed: 14499992)
28.Yasushi Furuichi, Akihiro Shimotsu, Hiro-O Ito, Yukari Namariyama, Yukiharu Yotsumoto, Youishi Hino, Yukie Mishige, Masakazu Inoue and Yuichi Izumi :
Associations of Periodontal Status with General Health Conditions and Aerum Antibody Titers for Porphyromonas gingivalis and Actinobacillus actinomycetemcomitans,
Journal of Periodontology, Vol.74, No.10, 1491-1497, 2003.
(DOI: 10.1902/jop.2003.74.10.1491,   PubMed: 14653396)
29.Hiro-O Ito, Toshihiro Nakashima, Takanori So, Masato Hirata and Masakazu Inoue :
Immunodominance of conformation-dependent B-cell epitopes of protein antigens,
Biochemical and Biophysical Research Communications, Vol.308, No.4, 770-776, 2003.
(DOI: 10.1016/S0006-291X(03)01466-9,   PubMed: 12927785)
30.Takanori So, Hiro-O Ito, Masato Hirata, Tadashi Ueda and Taiji Imoto :
Contribution of conformational stability of hen lysozyme to induction of type 2 T-helper immune responses,
Immunology, Vol.104, No.3, 259-268, 2001.
(DOI: 10.1046/j.1365-2567.2001.01314.x,   PubMed: 11722640)
31.Yoko Sakai, Hidetoshi Shimauchi, Hiro-O Ito, Masahiro Kitamura and Hiroshi Okada :
Porphyromonas gingivalisspecific lgG subclass antibody levels as immunological risk indicators of periodontal bone loss,
Journal of Clinical Periodontology, Vol.28, No.9, 853-859, 2001.
(DOI: 10.1034/j.1600-051x.2001.028009853.x,   PubMed: 11493355)
32.Y Furuichi, Hiro-O Ito, Y Izumi, T Matsuyama, Y Yotsumoto, Y Mishige, M Kojima, K Yamashita and M Inoue :
Periodontal status and serum antibody titers for Porphyromonas gingivalis fimbriae in a rural population in Japan,
Journal of Clinical Periodontology, Vol.28, No.3, 264-269, 2001.
(DOI: 10.1034/j.1600-051x.2001.028003264.x,   PubMed: 11284541,   Thomson Reuters: Web of Science™,   Elsevier: Scopus)
33.A Yoshida, Y Nakano, Y Yamashita, T Oho, Hiro-O Ito, M Kondo, M Ohishi and T Koga :
Immunodominant Region of Actinobacillus actinomycetemcomitans 40-kilodalton Heat Shock Protein in Patients with Rheumatoid Arthritis,
Journal of Dental Research, Vol.80, No.1, 346-350, 2001.
(DOI: 10.1177/00220345010800010901,   PubMed: 11269727,   Thomson Reuters: Web of Science™,   Elsevier: Scopus)
34.Hiroko Ito, Kimie Okimoto, Hiro-O Ito and Yoshihiro Terada :
Effect of Denture Application on senile patients, --- Relationship between mastication and immunological function ---,
Dentistry in Japan, Vol.36, 54-58, 2000.
35.Yasuko Okada, Katsuhiro Kitada, Masaru Takagaki, Hiro-O Ito and Masakazu Inoue :
Endocardiac infectivity and binding to extracellular matrix proteins of oral Abiotrophia species,
FEMS Immunology and Medical Microbiology, Vol.27, No.3, 257-261, 2000.
(DOI: 10.1016/S0928-8244(99)00193-5,   PubMed: 10683471,   Elsevier: Scopus)
36.Takanori So, Hiro-O Ito, Yoshiyuki Tsujihata, Masato Hirata, Tadashi Ueda and Taiji Imoto :
The molecular weight ratio of monomethoxypolyethylene glycol (mPEG) to protein determines the immunotolerogenicity of mPEG proteins,
Protein Engineering, Vol.12, No.8, 701-705, 1999.
(DOI: 10.1093/protein/12.8.701,   PubMed: 10469832)
37.T So, Hiro-O Ito, M Hirata, Tadashi Ueda and Taiji Imoto :
Extended blood half-life of monomethoxypolyethylene glycol-conjugated hen lysozyme is a key parameter controlling immunological tolerogenicity,
Cellular and Molecular Life Sciences, Vol.55, No.8,9, 1187-1194, 1999.
(DOI: 10.1007/s000180050365,   PubMed: 10442096)
38.Manabu Yanagita, Takachika Hiroi, Noriko Kitagaki, Shigeyuki Hamada, Hiro-O Ito, Hidetoshi Shimauchi, Shinya Murakami, Hiroshi Okada and Hiroshi Kiyono :
Nasopharyngeal-Associated Lymphoreticular Tissue (NALT) Immunity: Fimbriae-Specific Th1 and Th2 Cell-Regulated IgA Responses for the Inhibition of Bacterial Attachment to Epithelial Cells and Subsequent Inflammatory Cytokine Production,
The Journal of Immunology, Vol.162, No.6, 3559-3565, 1999.
39.Hiro-O Ito, Takanori So, Masato Hirata, T Koga, Tadashi Ueda and Taiji Imoto :
Tolerogenic activity of polyethylene glycol-conjugated lysozyme distinct from that of the native counterpart,
Immunology, Vol.93, No.2, 200-207, 1998.
40.Toshihiasa Kawai, Hiro-O Ito, Nobuo Sakato and Hiroshi Okada :
A novel approach for detecting an immunodominant antigen of Porphyromonas gingivalis in diagnosis of adult periodontitis,
Clinical and Diagnostic Laboratory Immunology, Vol.5, No.1, 11-17, 1998.
41.Takanori So, Hiro-O Ito, Toshitaka Koga, Sanae Watanabe, Tadashi Ueda and Taiji Imoto :
Depression of T-cell Epitope Generation by Stabilizing Hen Lysozyme,
The Journal of Biological Chemistry, Vol.272, No.51, 32136-32140, 1997.
42.Hiro-O Ito, T So, T Ueda, T Imoto and T Koga :
Prevention of collagen-induced arthritis (CIA) by treatment with polyethylene glycol-conjugated type II collagen; distinct tolerogenic property of the conjugated collagen from the native one,
Clinical and Experimental Immunology, Vol.108, No.2, 213-219, 1997.
43.Hiro-O Ito, M Hirata and T Koga :
Hen egg-white lysozyme inhibits biological activities of lipopolysaccharides from periodontopathic bacteria.,
Journal of Periodontal Research, Vol.32, No.3, 295-299, 1997.
44.Yoshiko Murakami, Yoshihisa Yamashita, Yoshio Nakano, Hiro-O Ito, Hao Yu and Toshihiko Koga :
Role of the Charged Tail in Localization of a Surface Protein Antigen of Streptococcus mutans,
Infection and Immunity, Vol.65, No.4, 1531-1535, 1997.
45.Hiro-O Ito, T Ueda, Y Hashimoto, T Imoto and T Koga :
Quaternary structure-dependent idiotope and antigen binding of a monoclonal antibody specific for conformational epitope on type II collagen,
Cellular and Molecular Life Sciences, Vol.53, No.1, 51-60, 1997.
(DOI: 10.1007/PL00000579,   PubMed: 9117997)
46.Hiro-O Ito, T Shuto, H Takada, T Koga, Y Aida and M Hirata :
Lipopolysaccharides from Porphyromonas gingivalis, prevotella intermedia and Actinobacillus actinomycetemcomitans promote osteoclastic differentiation in vitro,
Archives of Oral Biology, Vol.41, No.5, 439-444, 1996.
47.Takanori So, Hiro-O Ito, Toshitaka Koga, Tadashi Ueda and Taiji Imoto :
Reduced immunogenicity of monomethoxypolyethylene glycol-modified lysozyme for activation of T cells,
Immunology Letters, Vol.49, No.1,2, 91-97, 1996.
48.Yoko Sakai, Hiro-O Ito and Hiroshi Okada :
抗 Porphyromonas gingivalis 抗体の IgG サブクラスと歯周炎の病態,
Journal of the Japanese Association of Periodontology, Vol.36, No.4, 871-883, 1994.
49.Hiro-O Ito, J Morizet, L Coulombel and M Stanislawski :
T cell depletion of human bone marrow using an oxidase-peroxidase enzyme immunotoxin,
Bone Marrow Transplantation, Vol.6, No.6, 395-398, 1990.
50.Hiro-O Ito, V Rousseau, M Goavec, F Beaujean, J Morizet and M Stanislawski :
Enhanced in vitro cytotoxicity of 1,3-bis-(2-chloroethyl)-1-nitrosourea or buthionine sulfoximine combined with a reactive oxygen-generating enzyme immunotoxin,
Cancer Letters, Vol.49, No.2, 169-173, 1990.
51.Toshiyuki Okada, Yasushi Harada, Hiro-O Ito, Takenori Nozaki, Shigeyuki Ebisu, Shigenobu Kimura and Hiroshi Okada :
Actinomyces viscosus T14V 株の示す多クローン性B細胞活性化,
Journal of the Japanese Association of Periodontology, Vol.31, No.4, 1072-1080, 1989.
52.Stanislawski Marc, Rousseau Veronique, Goavec Martine and Hiro-O Ito :
Immunotoxins Containing Glucose Oxidase and Lactoperoxidase with Tumoricidal Properties: in Vitro Killing Effectiveness in a Mouse Plasmacytoma Cell Model,
Cancer Research, Vol.49, No.20, 5497-5504, 1989.
53.Hiro-O Ito, J Morizet, L Coulombel, M Goavec, V Rousseau and A Bernard :
An immunotoxin system intended for bone marrow purging composed of glucose oxidase and lactoperoxidase coupled to monoclonal antibody 097,
Bone Marrow Transplantation, Vol.4, No.5, 519-527, 1989.
54.H Okada, Y Shimabukuro, Y Kassai, Hiro-O Ito, Takashi Matsuo, S Ebisu and Y Harada :
The Function of Gingival Lymphocytes on the Establishment of Human Periodontitis,
Advances in dental research, Vol.2, No.2, 364-367, 1988.
55.Yasushi Harada, Hiro-O Ito, Yasuo Miki, Shigeyuki Ebisu and Hiroshi Okada :
Polyclonal induction of IgG antibody forming cells by stimulation with Actinomyces viscosus T14V,
Journal of Periodontal Research, Vol.23, No.2, 122-126, 1988.
56.Hiro-O Ito, Yasushi Harada, Takashi Matsuo, Shigeyuki Ebisu and Hiroshi Okada :
Possible role of T cells in the establishment of IgG plasma cell-rich periodontal lesion--Augmentation of IgG synthesis in the polyclonal B cell activation response by autoreactive T cells,
Journal of Periodontal Research, Vol.23, No.1, 39-45, 1988.
57.Hiroshi Okada, Hiro-O Ito and Yasushi Harada :
T-cell requirement for establishment of the IgG-dominant B-cell lesion in periodontitis,
Journal of Periodontal Research, Vol.22, No.3, 187-189, 1987.
58.Hiro-O Ito :
T Cells Modulate T-independent Polyclonal B Cell Activation and Enhance IgG Synthesis,
Journal of the Japanese Association of Periodontology, Vol.29, No.1, 22-36, 1987.

Review, Commentary:

1.Hiro-O Ito :
Periodontal disease, as a lifestyle-related disease, and as a risk factor for several other systemic lifestyle-related diseases,
Shikoku Acta Medica, Vol.65, No.5,6, 117-122, Dec. 2009.
(Tokushima University Institutional Repository: 110288,   CiNii: 40017005975)
2.Hiro-O Ito :
歯科治療と感染性心内膜炎の予防,
四国歯学誌, Vol.20, No.2, 191-198, 2008.
(Tokushima University Institutional Repository: 109762)
3.Hiro-O Ito :
Infective endocarditis and dental procedures: evidence, pathogenesis, and prevention,
The Journal of Medical Investigation : JMI, Vol.53, No.3-4, 189-198, Aug. 2006.
(Tokushima University Institutional Repository: 110807,   DOI: 10.2152/jmi.53.189,   PubMed: 16953053)
4.Hiro-O Ito :
牛乳とむし歯 (う蝕) 予防の関係(2),
Milk Science, Vol.51, No.3, 2002.
5.Hiro-O Ito :
牛乳とむし歯 (う蝕) 予防の関係(1),
Milk Science, Vol.51, No.2, 2002.
6.Hiro-O Ito :
免疫系の抗原認識と特異性,
鹿児島大学歯学部紀要, Vol.19, 23-33, Mar. 1999.
7.北田 勝浩, Hiro-O Ito and 井上 昌一 :
臨床現場でのう蝕予防の実践,
歯科医療, Vol.13, No.3, 5-19, 1999.
8.井本 泰治, 植田 正, Hiro-O Ito and 古賀 敏生 :
抗原のポリエチレングリコール修飾によるトレランス誘導,
Clinical Immunology, Vol.27, No.9, 1124-1128, Sep. 1995.
9.Hiro-O Ito :
免疫学からみた歯周病,
The Journal of Dental Medecine, Vol.31, No.6, 806-815, Jun. 1990.

Proceeding of International Conference:

1.Makoto Fukui, Kaname Miki, Kitamura Masayasu, Hayashida Hideaki, Kawasaki Koji, Rita Cristina Orihuela Campos, Naofumi Tamaki, Maeda Takahiro, Saito Toshiyuki and Hiro-O Ito :
Porphyromonas gingivalis infection may affect anti-atheroschlerotic antibody to phosphorylcholine.,
The 12th International Conference of Asia Academy of Preventive Dentistry, May 2016.
2.Rita Cristina Orihuela Campos, Naofumi Tamaki, Makoto Fukui, Kaname Miki and Hiro-O Ito :
Balance is the key: resveratrol revert oxidative stress conditions in gingival fibroblasts,
第93回IADR, Mar. 2015.
3.Naofumi Tamaki, Makoto Fukui, Hiro-O Ito and Kokeguchi Susumu :
Salivary Antioxidant Activity, Cytokines and Periodontitis: The Nagasaki Island Study,
International Association for Dental Research-Asia Pacific Region(IADR-APR), Bangkok, Aug. 2013.
4.Naofumi Tamaki and Hiro-O Ito :
Relationship between plasma reactive oxygen species and progression of periodontitis,
ICAAPD, ウランバートル, Feb. 2013.
5.Yoshihisa Yamashita and Hiro-O Ito :
Structural shift of microbiota in dental plaque formed on a hydroxyapatite disk surfaces in vivo.,
6th ASM Conference on Biofilms, マイアミシティー, Sep. 2012.
6.Hiro-O Ito :
Periodontal disease as a risk factor for several systemic lifestylerelated diseases. in Symposium 4: Addressing concerns in other oral conditions.,
ICAAPD, ウランバートル, Sep. 2012.
7.Makoto Fukui, Kaname Miki, Naofumi Tamaki and Hiro-O Ito :
Relationship between atherosclerosis and anti-phosphorylcholine antibodies in saliva and plasma,
ICAAPD, ウランバートル, Sep. 2012.
8.Naofumi Tamaki and Hiro-O Ito :
Relationship between plasma reactive oxygen species and progression of periodontitis,
ICAAPD, ウランバートル, Sep. 2012.
9.Naofumi Tamaki, Makoto Fukui and Hiro-O Ito :
Levels of Serum Markers of Oxidative Stress and Antibodies against Periodontal Pathogens in Community-dwelling Adults with and without Periodontitis: Goto Study,
International Conference on Porphyromonas gingivalis and Related Bacterial Species, Nagasaki, Aug. 2012.
10.Makoto Fukui, M. Mani, K. Uno, Kosuke Kataoka and Hiro-O Ito :
Cytokine profile in human saliva and its relationship with that in blood.,
9th International Conference Asian Academy of Preventive Dentistry, Kuala Lumpur, Malaysia, Nov. 2010.
11.Kosuke Kataoka, Ke. Fujihashi, R. Kobayashi, S. R. Gilbert, S. Sekine, Makoto Fukui, Y. Fukuyama, S. Kawabata, Hiro-O Ito and Ko. Fujihashi :
Nasal Cholera Toxin Activated Mucosal Densritic Cells, but not CD4+ Cells Elicits TI-IgA Class Switching Recombination by B-1 B Cells.,
14th International Congress of Immunology, Aug. 2010.
12.T. Baatarjav, Kosuke Kataoka, Makoto Fukui, A. S. Mulyatno, K. Fujihashi and Hiro-O Ito :
Nasal Vaccination with Phosphorylcholine plus Flt3 Ligand Gene as a Mucosal Adjuvant Inhibits Streptococcus pneumoniae Colonization.,
14th International Congress of Immunology, Kobe, Aug. 2010.
13.Makoto Fukui, Daisuke Hinode, Masaaki Yokoyama, Masami Yoshioka and Hiro-O Ito :
Salivary Stress Makers in Patients with Complaint of Halitosis.,
7th Congress of Asian Academy of Preventive Dentistry, Okayama, Nov. 2006.
14.Hiro-O Ito, M Fukui and al et :
Salivary stress markers in patients with complaint of halitosis.,
7th Congress of Asian Academy of Preventive Dentistry, Okayama, Nov. 2006.
15.Hiro-O Ito :
Prevention of infective endocarditis in dental procedures and combinatorial libraries,
The 2nd HiPep Okinawa International Workshop (Uruma, 沖縄バイオテクノロジー研究開発センター), Uruma, Okinawa, Jun. 2006.
16.H Okada, Y Shimabukuro, Y Kassai, Hiro-O Ito, Takashi Matsuo, S Ebisu and Y Harada :
The Function of Gingival Lymphocytes on the Establishment of Human Periodontitis,
Advances in dental research, Vol.2, No.2, 364-367, Kobe, Nov. 1988.

Proceeding of Domestic Conference:

1.楢崎 史也, 松岡 志織, Naofumi Tamaki, Makoto Fukui and Hiro-O Ito :
フッ化物洗口の口腔環境に及ぼす効果,
四国歯学会第50回例会, Mar. 2017.
2.Makoto Fukui, 早渕 純子, 西尾 よしみ, 竹内 早苗, 小百合 横山, Yumiko Izaki, Hiro-O Ito and Kenichi Maeda :
歯科検診10年の取り組み,
Oct. 2016.
3.Makoto Fukui, Kaname Miki, Rita Cristina Orihuela Campos, Naofumi Tamaki and Hiro-O Ito :
唾液潜血検査の判定を妨害する因子の検索,
第27回近畿・中国・四国口腔衛生学会・総会, Oct. 2016.
4.Rita Cristina Orihuela Campos, Naofumi Tamaki, Makoto Fukui and Hiro-O Ito :
Polyphenols reduce collateral damage in HGFs induced by oxidative stress,
44th Annual Meeting of the Japanese Society for Immunology, Nov. 2015.
5.Makoto Fukui, Rita Cristina Orihuela Campos, Naofumi Tamaki and Hiro-O Ito :
Influence of infection with Porphyromonas gingivalis on relationship between atherosclerosis and antiphosphorylcholine antibody,
44th Annual Meeting of the Japanese Society for Immunology, Nov. 2015.
6.Makoto Fukui, Kaname Miki, K Kitamura, H Hayashida, K Kawasaki, Rita Cristina Orihuela Campos, Naofumi Tamaki, T Maeda, T Saito and Hiro-O Ito :
Atherosclerosis-preventive activity of anti-phosphorylcholine antibody may be interfered by infection with Porphyromonas gingivalis : The Nagasaki Islands study,
63rd Annual Meeting of the Japanese Association of Dental Research, Oct. 2015.
7.岡田 寿郎, 福井 隆夫, 藤村 英二, 大月 陽子, 西 雅子, 豊島 健治, Makoto Fukui, Naofumi Tamaki, Hiro-O Ito and 奥 弘文 :
日本歯科医師会の``生活支援プログラム''による健診事業の参加者の満足度および行動変容への効果,
第26回 近畿・中国・四国 口腔衛生学会総会, Sep. 2015.
8.鈴木 雅博, 水野 昭彦, 松尾 亮, Naofumi Tamaki, Makoto Fukui and Hiro-O Ito :
糖尿病教育入院患者における歯肉溝液中の炎症関連バイオマーカーの経時的変化,
第26回 近畿・中国・四国 口腔衛生学会総会, Sep. 2015.
9.橋本 智惠子, 西窪 美波, Naofumi Tamaki, Makoto Fukui and Hiro-O Ito :
キシリトールガム咀嚼による唾液分泌能と唾液細菌叢の変化,
第45回 四国歯学会, Jun. 2015.
10.水野 昭彦, 松尾 亮, 鈴木 雅博, Naofumi Tamaki, Makoto Fukui, Kaname Miki, 松瀬 亮一 and Hiro-O Ito :
市民検診と糖尿病患者データにおける歯肉溝浸出液バイオマーカーの比較検討,
第64回 口腔衛生学会総会, May 2015.
11.Naofumi Tamaki, Rita Cristina Orihuela Campos, Makoto Fukui, Kaname Miki and Hiro-O Ito :
水素水の抗酸化・抗炎症作用の検討,
第64回 口腔衛生学会総会, May 2015.
12.Makoto Fukui, 岡田 寿郎, Kaname Miki, Naofumi Tamaki and Hiro-O Ito :
``標準的な成人歯科健診プログラム・保健指導マニュアル''に基づいた歯科保健事業の効果について,
第64回 口腔衛生学会総会, May 2015.
13.松尾 亮, 水野 昭彦, 鈴木 雅博, Naofumi Tamaki, Makoto Fukui, Kaname Miki and Hiro-O Ito :
歯肉溝浸出液バイオマーカーと血液データの比較検討,
第49回日本成人病(生活習慣病)学会, Jan. 2015.
14.Makoto Fukui, Kaname Miki, Rita Cristina Orihuela Campos, Naofumi Tamaki and Hiro-O Ito :
Levels of various cytokines in human saliva from generally healthy individuals.,
62nd Annual Meeting of the Japanese Association for Dental Research, Dec. 2014.
15.福井 隆夫, 小林 弘茂, 渋谷 敦人, Jurou Okada, 豊嶋 健, Makoto Fukui, Naofumi Tamaki, Hiro-O Ito and 弘文 奥 :
日歯生活歯援プログラムに基づく平成25年度成人歯科健診事業実施報告,
第25回 近畿・中国・四国 口腔衛生学会総会, Oct. 2014.
16.高尾 健二郎, 新居 麻美子, Makoto Fukui, Kaname Miki, Rita Cristina Orihuela Campos, Naofumi Tamaki and Hiro-O Ito :
歯肉炎症の客観的・定量的診断を目指した市販免疫クロマトグラフィー唾液潜血テストの改良,
第25回 近畿・中国・四国 口腔衛生学会総会, Oct. 2014.
17.水野 昭彦, 松尾 亮, Naofumi Tamaki, Makoto Fukui, Kaname Miki and Hiro-O Ito :
歯肉溝浸出液バイオマーカーと血液データの比較,
第25回 近畿・中国・四国 口腔衛生学会総会, Oct. 2014.
18.Naofumi Tamaki, 水野 昭彦, 松尾 亮, 正木 文浩, 中川 徹, 鈴木 雅博, 青木 良平, 松瀬 亮一, Makoto Fukui and Hiro-O Ito :
歯肉溝浸出液中バイオマーカーと腎機能・糖尿病指標との関連,
第7回 日本口腔検査学会総会・学術大会, Sep. 2014.
19.Rita Cristina Orihuela Campos, Naofumi Tamaki, Makoto Fukui, Kaname Miki and Hiro-O Ito :
Effects of three different antioxidants on human gingival fibroblasts exposed to oxidative stress,
2014 Tokushima Bioscience retreat, Sep. 2014.
20.Makoto Fukui, Kaname Miki, Rita Cristina Orihuela Campos, Naofumi Tamaki and Hiro-O Ito :
健常者における唾液中サイトカインプロファイルの解析,
第63回 口腔衛生学会総会, May 2014.
21.Rita Cristina Orihuela Campos, Naofumi Tamaki, Makoto Fukui, Kaname Miki and Hiro-O Ito :
Effects of three antioxidant compounds on human gingival fibroblasts under oxidative stress,
第63回 口腔衛生学会総会, May 2014.
22.Naofumi Tamaki, Rita Cristina Orihuela Campos, Makoto Fukui and Hiro-O Ito :
口蓋創傷治癒モデルにおける水素水摂取の効果,
第4回分子状水素医学シンポジウム, Feb. 2014.
23.Rita Cristina Orihuela Campos, Naofumi Tamaki, Makoto Fukui, Kaname Miki and Hiro-O Ito :
Effects of different antioxidants on human gingival fibroblasts under oxidative stress,
第5回心・血管クラスターミニリトリート, Jan. 2014.
24.小林 弘茂, 渋谷 敦人, 福井 隆夫, Jurou Okada, 豊嶋 健治, Makoto Fukui, Naofumi Tamaki, Hiro-O Ito and 弘文 奥 :
日歯プログラムに基づく成人歯科健診における唾液検査および質問紙調査と歯周状態の関連性について,
第24回近畿・中国・四国口腔衛生学会総会, Oct. 2013.
25.Makoto Fukui, Kaname Miki, Naofumi Tamaki and Hiro-O Ito :
唾液中サイトカインと口腔健康状態の関連性,
第24回近畿・中国・四国口腔衛生学会総会, Oct. 2013.
26.Makoto Fukui, Naofumi Tamaki and Hiro-O Ito :
唾液を用いた高齢者の口腔健康状態把握のための基盤的研究,
第56回秋季日本歯周病学会学術大会, Sep. 2013.
27.Hiro-O Ito :
公衆衛生学的視点から見た歯肉の健康指標の現状と将来展望. 学会主導企画シンポジウム「歯周病の予防戦略」,
第56回秋季日本歯周病学会, Sep. 2013.
28.Hiro-O Ito :
公衆衛生学的視点から見た歯肉の健康指標の現状と将来展望. 学会主導企画シンポジウム「歯周病の予防戦略」,
第56回秋季日本歯周病学会, Sep. 2013.
29.Rita Cristina Orihuela Campos, Naofumi Tamaki, Makoto Fukui, Kaname Miki and Hiro-O Ito :
Effects of different antioxidants on the biological properties of human gingival fibroblasts response toward ROS,
Tokushima Bioscience retreat, Sep. 2013.
30.Murasaki Miyagi, Mitsutaka Kimura, Shohei Inoue, Michiyasu Nakao, Shigeki Sano, Makoto Fukui and Hiro-O Ito :
A Modified OPA Method for a Valid Measure of Oral Malodor,
第11回プロセス化学東四国フォーラムセミナー, Jun. 2013.
31.Rita Cristina Orihuela Campos, Naofumi Tamaki, Makoto Fukui, Kaname Miki and Hiro-O Ito :
Real time xCELLigence analysis of antioxidant agents on human gingival fibroblast cells viability,
第62回日本口腔衛生学会総会, May 2013.
32.Makoto Fukui, Kaname Miki, Rita Cristina Orihuela Campos, Naofumi Tamaki and Hiro-O Ito :
健常者における唾液中サイトカイン分析,
第62回日本口腔衛生学会・総会, May 2013.
33.Murasaki Miyagi, Mitsutaka Kimura, Shohei Inoue, Michiyasu Nakao, Shigeki Sano, Makoto Fukui and Hiro-O Ito :
A Modified OPA Method for a Valid Measure of Oral Malodor,
日本薬学会第133年会, Mar. 2013.
34.Makoto Fukui, Naofumi Tamaki, Kaname Miki and Hiro-O Ito :
動脈硬化リスク評価のための唾液・血液中の抗ホスホリルコリン抗体の測定,
心血管クラスターリトリート, Jan. 2013.
35.SA Mulyatno, Naofumi Tamaki, Makoto Fukui and Hiro-O Ito :
Mucosal adjuvanticity of bacterial lipopolysaccharide in compared with cholera toxin,
Proceedings of the Japanese Society for Immunology, Dec. 2012.
36.Jurou Okada, 小林 宏茂, 福井 隆夫, 渋谷 敦人, 裕光 武部, 豊嶋 健治, Makoto Fukui, Hiro-O Ito and 弘文 奥 :
平成22年度に香川県内で実施された成人歯科健診モデル事業実施報告,
第22回日本歯科医学会総会, Nov. 2012.
37.Murasaki Miyagi, Mitsutaka Kimura, Shohei Inoue, Michiyasu Nakao, Shigeki Sano, Makoto Fukui and Hiro-O Ito :
オルトフタルアルデヒド法を基盤とした新規メチルメルカプタン蛍光標識法,
第51回日本薬学会・日本薬剤師会・日本病院薬剤師会中国四国支部学術大会, Nov. 2012.
38.天羽 崇, Daisuke Hinode, 平島 美穂, Masami Yoshioka, Masaaki Yokoyama, Kanako Tamatani, Makoto Fukui, Hiro-O Ito and Kosuke Kataoka :
舌苔中の歯周病関連細菌と口臭との関連性,
第23回近畿中国四国口腔衛生学会総会, Oct. 2012.
39.Makoto Fukui, Naofumi Tamaki and Hiro-O Ito :
成人歯科健診事業における唾液検査と歯周所見の一致性について,
第23回近畿中国四国口腔衛生学会総会, Oct. 2012.
40.Makoto Fukui, Naofumi Tamaki and Hiro-O Ito :
平成23年度に香川県内で実施した「成人歯科健診モデル事業」における保健行動目標の達成状況について,
第23回近畿中国四国口腔衛生学会総会, Oct. 2012.
41.Makoto Fukui, Kaname Miki, Naofumi Tamaki and Hiro-O Ito :
動脈硬化リスク評価のための唾液・血液中の抗ホスホリルコリン抗体の測定,
第5回日本口腔検査学会総会・学術大会, Aug. 2012.
42.Naofumi Tamaki and Hiro-O Ito :
歯周病進行と酸化ストレス,
Shikoku Dental Research, Jun. 2012.
43.SA Mulyatno, Kosuke Kataoka, Makoto Fukui, Kaname Miki, RC Orihuela-Campos and Hiro-O Ito :
Modulation of Mucosal Immune Response by Bacterial Lipopolysaccharide in Nasal Vaccination Model,
第61回日本口腔衛生学会・総会, May 2012.
44.Makoto Fukui, SA Mulyatno, Masaki GOTO, Kaname Miki, RC Orihuela-Campos, Kosuke Kataoka, 林田 秀明, 北村 雅保, 川崎 浩二, 関田 孝晴, 中里 未央, 前田 隆浩, 齋藤 俊行 and Hiro-O Ito :
ヒト唾液中および血中の抗ホスホリルコリン抗体と動脈硬化リスクとの関連性-第二報-,
第61回日本口腔衛生学会・総会, May 2012.
45.Makoto Fukui, ムルヤトノ サプタ, バータルジャフ ツェルメグ, Masaki GOTO, Kosuke Kataoka, 林田 秀明, 川崎 浩二, 前田 隆浩, 中里 未央, 齋藤 俊行 and Hiro-O Ito :
ヒト唾液中および血中の抗ホスホリルコリン抗体と動脈硬化リスクとの関連性:五島研究,
Oct. 2011.
46.ムルヤトノ サプタ, Kosuke Kataoka, 関根 伸一, バータルジャブ ツェルメグ, Makoto Fukui, 金川 裕子, Masaki GOTO and Hiro-O Ito :
経鼻粘膜アジュバントCpG ODNはマクロファージのTLR9発現と歯周病細菌抗原特異的Th1免疫応答を誘導する,
Oct. 2011.
47.渋谷 敦人, 小林 弘茂, 福井 隆夫, Jurou Okada, 豊嶋 健治, Makoto Fukui, Kosuke Kataoka, Hiro-O Ito and 奥 弘文 :
平成22年度に香川県内で実施された成人歯科健診モデル事業実施報告,
Oct. 2011.
48.T. Baatarjav, Kosuke Kataoka, S. Mulyatno, Makoto Fukui, H. Kanagawa and Hiro-O Ito :
Nasal Flt3L gene results in mucosal immune responses to PC through induction of B-1 B cells.,
第59回口腔衛生学会総会, Oct. 2010.
49.Kosuke Kataoka, 関根 伸一, バータルジャフ ツェルメグ, ムルヤトノ サプタ, Makoto Fukui, 金川 裕子 and Hiro-O Ito :
遺伝子改変植物による歯周病原菌定着阻害能を有するヒト唾液タンパク質スタセリンペプチドの発現,
第59回口腔衛生学会総会, Oct. 2010.
50.Makoto Fukui, ムルヤトノ サプタ, バータルジャフ ツェルメグ, Kosuke Kataoka, 林田 秀明, 川崎 浩二, 斎藤 俊行 and Hiro-O Ito :
ヒト血中および唾液中の抗ホスホリルコリン抗体の存在実態,
第59回口腔衛生学会総会, Oct. 2010.
51.Kosuke Kataoka, 関根 伸一, Makoto Fukui, Masaaki Yokoyama and Hiro-O Ito :
粘膜アジュバントCpG オリゴヌクレオチドによるPorphyromonas gingivalis 線毛抗原特異的抗体応答の誘導,
第53回日本歯周病学会秋季学術大会, Sep. 2010.
52.Kosuke Kataoka, Makoto Fukui, 金川 裕子 and Hiro-O Ito :
ヒト唾液タンパク質由来ペプチドの歯周病菌定着阻害効果,
第21回近畿・中国・四国口腔衛生学会総会, Jun. 2010.
53.Makoto Fukui, サプタ ムルヤトノ, バータルジャフ ツェルメグ, Kosuke Kataoka and Hiro-O Ito :
ヒトの唾液中および血中に存在する抗ホスホリルコリン抗体の検出,
第21回近畿・中国・四国口腔衛生学会総会, Jun. 2010.
54.Masakazu Misaki, 渋谷 敦人, Jurou Okada, 阿部 直樹, 豊嶋 健治, Makoto Fukui, Kosuke Kataoka, Hiro-O Ito and 弘文 奥 :
平成21年度に香川県内で実施された成人歯科健診モデル事業実施報告,
第21回近畿・中国・四国口腔衛生学会総会, Jun. 2010.
55.Kosuke Kataoka, Haruo Nakagaki, 関根 伸一, Makoto Fukui, Hiro-O Ito and Satoshi Shizukuishi :
Fusobacterium nucleatum表層タンパク質FomAと唾液高チロシンタンパク質スタセリンペプチドとの相互作用,
第53回日本歯周病学会春季学術大会, May 2010.
56.Kosuke Kataoka, Hiro-O Ito, Makoto Fukui, Baatarjav Tselmeg and 藤橋 浩太郎 :
Induction of PC-specific T15 idiotype Ab in mucosal secretion by Flt3 ligand plasmid as a mucosal adjuvant,
日本免疫学会総会学術集会記録, Vol.39, 193, Dec. 2009.
57.Akinobu Morimoto, Michiyasu Nakao, Shigeki Sano and Hiro-O Ito :
OPA法ならびにエルマン法を基盤とするチオール捕捉標識反応剤の合成開発,
第48回日本薬学会・日本薬剤師会・日本病院薬剤師会中国四国支部学術大会, Nov. 2009.
58.高松 夏子, 福井 誠, 片岡 宏介, 泉福 英信 and Hiro-O Ito :
歯根面う蝕発生における唾液中抗PAc (361-386) IgA 抗体の役割,
第59回日本口腔衛生学会総会(岐阜市,長良川国際会議場)2009年10月10日 口腔衛生学会雑誌, Vol.59, No.4, 367, Oct. 2009.
59.バータルジャフ ツェルメグ, ムルヤトノ サプタ, 金川 裕子, Kosuke Kataoka, Hiro-O Ito and Makoto Fukui :
唾液タンパク質由来ペプチド複合体による歯周病菌定着阻害能の検討,
第59回日本口腔衛生学会総会(岐阜市,長良川国際会議場) 口腔衛生学会雑誌, Vol.59, No.4, 349, Oct. 2009.
60.岡田 寿朗, 三崎 昌和, 佐々木 浩司, 武部 裕光, 山下 喜世弘, Makoto Fukui, Hiro-O Ito and 奥 弘文 :
香川県内で実施された歯科保健指導モデル事業報告,
第20回日本口腔衛生学会近畿·中国·四国地方会 (広島国際会議場), Jun. 2009.
61.金川 裕子, 福井 誠, 米津 隆仁, 横山 正秋, 安達 聡, ツェルメグ B., 片岡 宏介 and Hiro-O Ito :
徳島県民の歯科定期歯科健診受診行動に関する心理的要因の調査,
第20回日本口腔衛生学会近畿·中国·四国地方会 (広島国際会議場), Jun. 2009.
62.Makoto Fukui and Hiro-O Ito :
フゾバクテリウム反応性唾液sIgA抗体と舌苔との関連性,
第20回日本口腔衛生学会近畿·中国·四国地方会 (広島国際会議場), Jun. 2009.
63.Makoto Fukui, Daisuke Hinode, Masaaki Yokoyama, バータルジャフ ツェルメグ, Kosuke Kataoka and Hiro-O Ito :
フゾバクテリウム反応性唾液sIgA抗体と舌苔との関連性,
Journal of Dental Health, Vol.59, No.5, 606-607, Jun. 2009.
64.万井 正章, 宇野 賀津子, Makoto Fukui and Hiro-O Ito :
唾液中サイトカイン測定の健康診査への応用に関する研究,
第74回日本インターフェロン・サイトカイン学会学術集会(京都大学芝蘭会館), Jun. 2009.
65.Hiro-O Ito, B. ツェルメグ, Kosuke Kataoka and Makoto Fukui :
肺炎球菌抗原とDNAアジュバント経鼻投与による粘膜免疫応答の解析,
第20回日本口腔衛生学会近畿·中国·四国地方会 (広島国際会議場), Jun. 2009.
66.Akinobu Morimoto, Shigeki Sano, Yoshimitsu Nagao and Hiro-O Ito :
Synthetic Development of Methanethiol-Trapping Agents,
日本薬学会第129年会, Mar. 2009.
67.Akinobu Morimoto, Shigeki Sano, Yoshimitsu Nagao and Hiro-O Ito :
揮発性チオール捕捉反応剤の合成開発研究,
第47回日本薬学会·日本薬剤師会·日本病院薬剤師会中国四国支部学術大会, Nov. 2008.
68.Jurou Okada, Masakazu Misaki, 浩司 佐々木, 裕光 武部, 喜世弘 山下, Masaaki Yokoyama, Makoto Fukui, Hiro-O Ito and 弘文 奥 :
香川県内で実施された成人歯科健診モデル事業報告,
The Journal of the Japan Dental Association, Vol.61, No.5, 555, Aug. 2008.
69.Masaaki Yokoyama, Makoto Fukui, Tomoaki Honna, Natsuko Takamatsu, Kaname Masuda and Hiro-O Ito :
口腔清潔度の指標としての唾液中総細菌数,
Journal of Dental Health, Vol.57, No.5, 692, Oct. 2007.
70.Jurou Okada, Masakazu Misaki, 浩司 佐々木, 稔之 亀井, 裕光 武部, 喜世弘 山下, Masaaki Yokoyama, Makoto Fukui, Hiro-O Ito and 弘文 奥 :
香川県内で実施された成人歯科健診モデル事業報告,
Journal of Dental Health, Vol.57, No.5, 689, Oct. 2007.
71.Makoto Fukui, Daisuke Hinode, Masaaki Yokoyama, Masami Yoshioka and Hiro-O Ito :
口臭患者における唾液ストレスマーカーの評価,
Journal of Dental Health, Vol.57, No.4, 482, Aug. 2007.
72.Natsuko Takamatsu, Kaname Masuda, Makoto Fukui, Masaaki Yokoyama, Masami Yoshioka and Hiro-O Ito :
歯根面う蝕のリスクファクター調査,
Journal of Dental Health, Vol.57, No.4, 423, Aug. 2007.
73.Masaaki Yokoyama, Daisuke Hinode, Makoto Fukui, Masami Yoshioka and Hiro-O Ito :
歯周病原細菌Campylobacter rectusと妊娠期の歯周状態との関連性,
Journal of the Japanese Association of Periodontology, Vol.49, 176, Aug. 2007.
74.Masaaki Yokoyama, Daisuke Hinode, Makoto Fukui, Masami Yoshioka and Hiro-O Ito :
Relationship between Campylobacter rectus and periodontal status during pregnancy,
「魅力ある大学院教育」イニシアティブ・第1回国際シンポジウム, Mar. 2007.
75.Masami Yoshioka, Tomoaki Honna, Makoto Fukui, Masaaki Yokoyama, Shin-ichi Tanabe, Kaname Masuda, Daisuke Hinode and Hiro-O Ito :
学校歯科健診における歯肉炎の評価についての考察,
Journal of Dental Health, Vol.56, No.5, 723, Oct. 2006.
76.横山 正明, Hiro-O Ito and :
妊婦における歯周疾患と唾液中の女性ホルモンおよび血管内皮増殖因子(VEGF)の関連性,
第55回日本口腔衛生学会総会, Oct. 2006.
77.吉岡 昌美, Hiro-O Ito and :
学校歯科健診における歯肉炎の評価についての考察,
第55回日本口腔衛生学会総会, Oct. 2006.
78.Hiro-O Ito :
シンポジウム5「口腔保健の免疫学的展開」口腔常在菌のホスホリルコリン抗原決定基に対する免疫応答の誘導と,抗肺炎球菌応答の修飾について,
第55回日本口腔衛生学会総会, Oct. 2006.
79.Masaaki Yokoyama, Daisuke Hinode, Makoto Fukui, Shin-ichi Tanabe, Masami Yoshioka and Hiro-O Ito :
妊婦における歯周疾患と唾液中の女性ホルモンおよび血管内皮増殖因子(VEGF)の関連性,
Journal of Dental Health, Vol.56, No.4, 593, Aug. 2006.
80.Hiro-O Ito :
歯学・歯科医療におけるサイエンスとエビデンスの融合を求めて,
第30回 四国歯学会総会(徳島大学歯学部), Jul. 2006.
81.吉岡 昌美, Hiro-O Ito and :
吉岡昌美ら,学校歯科健診における歯肉炎の評価についての考察,
第17回日本口腔衛生学会近畿·中国·四国地方会 (和歌山県歯科医師会館), Jun. 2006.

Et cetera, Workshop:

1.Makoto Fukui, 早渕 純子, 西尾 よしみ, 武内 早苗, 小百合 横山, Yumiko Izaki, Hiro-O Ito and Kenichi Maeda :
歯科検診10年の取り組み,
全国大学保健管理研究集会プログラム・抄録集, 51, Sep. 2016.

Grants-in-Aid for Scientific Research (KAKEN Grants Database @ NII.ac.jp)

  • 天然ハーブ・キャッツクローの抗酸化作用と歯周病予防に関する基礎的研究 (Project/Area Number: 16K11859 )
  • 生体反応の化学的測定に基づく客観的な新規歯周病診断システムの開発 (Project/Area Number: 26293442 )
  • Relationship between periodontitis and salivary antioxidant activity by ESR (Project/Area Number: 24593155 )
  • Decision of a normal range of cytokines in human saliva. (Project/Area Number: 23593091 )
  • Development of high-throughput analysis formouth odor (Project/Area Number: 22592336 )
  • 天然ペプチドライブラリーからのカンジダ菌定着抑制物質の検索 (Project/Area Number: 19592406 )
  • Elucidation of mechanism of enhanced innate salivary-IgA antibody to Thymus-independent antigen (Project/Area Number: 19592403 )
  • Search for inhibitory structures against adhesions of bacteria : construction and application of designed peptide libraries intended for prevention of infective endoearditis (Project/Area Number: 18390569 )
  • 感染症局所病変の病型決定に関与する宿主遺伝子の探索 (Project/Area Number: 17659593 )
  • Prevention of infectious diseases through inhibition of bacterial adherence to host tissues. (Project/Area Number: 16390540 )
  • Experimental infective endocarditis induced by human supragingival dental plaque (Project/Area Number: 15592211 )
  • Peripheral blood samples for screening individuals with periodontal disease (Project/Area Number: 12672037 )
  • A search for a synthesized vaccine candidate intended for periodontal diseases ; on the basis of the conformation dependent characteristics of the dominant epitope of periodontal pathogen, Porphyromonas gingivalis. (Project/Area Number: 12557188 )
  • Searches for lead compounds intended for prevention of infective endocarditis by means of combinatorial chemical libraries. (Project/Area Number: 12557187 )
  • Analysis of gene of Granulicatella adiacens fibronectin-binding protein and application of the gene for clinical diagnosis. (Project/Area Number: 12470464 )
  • Epitope structure of fibronectin that recognized by bacterial adhesins (Project/Area Number: 11671873 )
  • Mechanism of "S.millerli" to adhere with internal organs : a laminin-mediated process (Project/Area Number: 09672112 )
  • INFLUENCE OF FUNCTION ON IMMUNE SYSTEM -EFFECT OF DENTURE ON IMMUNOLOGICAL PARAMETERS- (Project/Area Number: 09671994 )
  • Analysis of epitope specificity of immune response involved in periodontitis (Project/Area Number: 09671924 )
  • タンパク質の高次構造に依存する抗原エピトープ同定法の開発 (Project/Area Number: 08877282 )
  • 抗原と抗体の特異的結合に関与する立体構造の同定 (Project/Area Number: 07857135 )
  • Interaction between Bacterial Endotoxin and Lysozyme (Project/Area Number: 07457448 )
  • 歯周病関連細菌のリポ多糖がは破骨細胞の分化ならびに活性化に及ぼす影響 (Project/Area Number: 06771669 )
  • 歯周炎患者の免疫応答の特異性(歯周病原性細菌特異的反応と自己交叉反応の相関について) (Project/Area Number: 05671595 )
  • Signal transduction in osteoblasts and osteoclasts. (Project/Area Number: 05454511 )
  • 歯周炎患者の体液性免疫応答の特異性(Porphgromonas gingivalisの主要抗原の同定・特に多糖抗原に関して) (Project/Area Number: 04671157 )
  • Diagnostic method of high risk patient for period on titis by martivariate statistical analysis (Project/Area Number: 04454471 )
  • Immunoregulatory Mechanisms in Adult Periodontitis (Project/Area Number: 03404056 )
  • 歯周疾患における線維芽細胞と免疫担当細胞間相互作用に関する研究 (Project/Area Number: 01571042 )
  • Search by Researcher Number (40213079)