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Research Activity

Field of Study

Medicine

Subject of Study

Book / Paper

Academic Paper (Judged Full Paper):

1. Soo Hyeon Kim, Yuji Shishido, Hirofumi Sogabe, Wanitcha Rachadech, Kazuko YORITA, Yusuke Kato and Kiyoshi Fukui :
Age- and gender-dependent D-amino acid oxidase activity in mouse brain and peripheral tissues: implication for aging and neurodegeneration,
The Journal of Biochemistry, Vol.166, No.2, 187-196, 2019.
(Tokushima University Institutional Repository: 113627,   DOI: 10.1093/jb/mvz025,   PubMed: 30938755)
2. Diem Hong Tran, Yuji Shishido, Seongpil Chung, Huong Thi Thanh Trinh, Kazuko YORITA, Takashi Sakai and Kiyoshi Fukui :
Identification of DNA-binding proteins that interact with the 5-flanking region of the human d-amino acid oxidase gene by pull-down assay coupled with two-dimensional gel electrophoresis and mass spectrometry,
Journal of Pharmaceutical and Biomedical Analysis, Vol.116, 94-100, 2015.
(DOI: 10.1016/j.jpba.2015.02.031,   PubMed: 25749303)
3. Huy Van Dang, Takashi Sakai, Tuan Anh Pham, Diem Hong Tran, Kazuko YORITA, Yuji Shishido and Kiyoshi Fukui :
Nucling, a Novel Apoptosis-associated Protein, Controls Mammary Gland Involution by Regulating NF-B and STAT3,
The Journal of Biological Chemistry, Vol.290, No.40, 24626-24635, 2015.
(Tokushima University Institutional Repository: 109502,   DOI: 10.1074/jbc.M115.673848,   PubMed: 26269594)
4. Diem Hong Tran, Yuji Shishido, Seongpil Chung, Huong Thi Thanh Trinh, Kazuko YORITA, Takashi Sakai and Kiyoshi Fukui :
Identification of two promoters for human D-amino acid oxidase gene: implication for the differential promoter regulation mediated by PAX5/PAX2,
The Journal of Biochemistry, Vol.157, No.5, 377-387, 2015.
(Tokushima University Institutional Repository: 106442,   DOI: 10.1093/jb/mvu084,   PubMed: 25500505,   Elsevier: Scopus)
5. Salah Mohamed El-Sayed, Rabab Mohamed Abou El-Magd, Yuji Shishido, Kazuko YORITA, Seongpil Chung, Diem Hong Tran, Takashi Sakai, Hiroyoshi Watanabe, Shoji Kagami and Kiyoshi Fukui :
D-Amino acid oxidase-induced oxidative stress, 3-bromopyruvate and citrate inhibit angiogenesis, exhibiting potent anticancer effects,
Journal of Bioenergetics and Biomembranes, Vol.44, No.5, 513-523, 2012.
(DOI: 10.1007/s10863-012-9455-y,   PubMed: 22802136)
6. Salah Mohamed El-Sayed, Rabab Mohamed Abou El-Magd, Yuji Shishido, Seongpil Chung, Diem Hong Tran, Takashi Sakai, Hiroyoshi Watanabe, Shoji Kagami and Kiyoshi Fukui :
3-Bromopyruvate antagonizes effects of lactate and pyruvate, synergizes with citrate and exerts novel anti-glioma effects,
Journal of Bioenergetics and Biomembranes, Vol.44, No.1, 61-79, 2012.
(DOI: 10.1007/s10863-012-9409-4,   PubMed: 22318356,   Elsevier: Scopus)
7. Salah Mohamed El-Sayed, Rabab Mohamed Abou El-Magd, Yuji Shishido, Seongpil Chung, Takashi Sakai, Hiroyoshi Watanabe, Shoji Kagami and Kiyoshi Fukui :
D-amino acid oxidase gene therapy sensitizes glioma cells to the antiglycolytic effect of 3-bromopyruvate,
Cancer Gene Therapy, Vol.19, No.1, 1-18, 2012.
(DOI: 10.1038/cgt.2011.59,   PubMed: 21921941)
8. Iwakura Yuriko, Wang Ran, Abe Yuichi, Piao Ying-shan, Yuji Shishido, Higashiyama Shigeki, Takei Nobuyuki and Nawa Hiroyuki :
Dopamine-dependent ectodomain shedding and release of epidermal growth factor in developing striatum: target-derived neurotrophic signaling (Part 2).,
Journal of Neurochemistry, Vol.118, No.1, 57-68, 2011.
(DOI: 10.1111/j.1471-4159.2011.07295.x,   PubMed: 21534959)
9. Seongpil Chung, Sogabe Kimiko, Hwan Ki Park, Ying Song, Koji Ono, Rabab Mohamed Abou El-Magd, Yuji Shishido, Kazuko YORITA, Takashi Sakai and Kiyoshi Fukui :
Potential cytotoxic effect of hydroxypyruvate produced from D-serine by astroglial D-amino acid oxidase,
The Journal of Biochemistry, Vol.148, No.6, 743-753, 2010.
(DOI: 10.1093/jb/mvq112,   PubMed: 20876609)
10. Rabab Mohamed Abou El-Magd, Chizuru Sasaki, Tomoya Kawazoe, Salah Mohamed El-Sayed, Kazuko YORITA, Yuji Shishido, Takashi Sakai, Yoshitoshi Nakamura and Kiyoshi Fukui :
Bioprocess development of the production of the mutant P-219-L human D-amino acid oxidase for high soluble fraction expression in recombinant Escherichia coli,
Biochemical Engineering Journal, Vol.52, No.2-3, 236-247, 2010.
(DOI: 10.1016/j.bej.2010.08.016)
11. Koji Ono, Yuji Shishido, Hwan Ki Park, Tomoya Kawazoe, Sanae Iwana, Seongpil Chung, Rabab Mohamed Abou El-Magd, Kazuko YORITA, Mai Okano, Takeshi Watanabe, Nobuya Sano, Yoshimi Bando, Kunimasa Arima, Takashi Sakai and Kiyoshi Fukui :
Potential pathophysiological role of D-amino acid oxidase in schizophrenia: immunohistochemical and in situ hybridization study of the expression in human and rat brain,
Journal of Neural Transmission, Vol.116, No.10, 1335-1347, 2009.
(DOI: 10.1007/s00702-009-0289-7,   PubMed: 19685198)
12. Yuji Shishido, Takayuki Tanaka, Ying-Shan Piao, Kazuaki Araki, Nobuyuki Takei, Shigeki Higashiyama and Hiroyuki Nawa :
Activity-dependent shedding of heparin-binding EGF-like growth factor in brain neurons.,
Biochemical and Biophysical Research Communications, Vol.348, No.3, 963-970, 2006.
(DOI: 10.1016/j.bbrc.2006.07.129,   PubMed: 16901467)
13. Hwan Ki Park, Yuji Shishido, Sayaka Ichise-Shishido, Tomoya Kawazoe, Koji Ono, Sanae Iwana, Yumiko Tomita, Kazuko YORITA, Takashi Sakai and Kiyoshi Fukui :
Potential Role for Astroglial D-Amino Acid Oxidase in Extracelluar D-Serine Metabolism and Cytotoxicity,
The Journal of Biochemistry, Vol.139, No.2, 295-304, 2006.
(DOI: 10.1093/jb/mvj036,   PubMed: 16452318)
14. Kimi Yamakoshi, Yuji Shishido and Noriyuki Shimoda :
Generation of Aberrant Transcripts of and Free DNA Ends in Zebrafish no tail Gene,
Marine Biotechnology, Vol.7, No.3, 163-172, 2005.
(DOI: 10.1007/s10126-004-3500-8,   PubMed: 15933901)
15. Takazaki Risa, Yuji Shishido, Iwamoto Ryo and Mekada Eisuke :
Suppression of the Biological Activities of the Epidermal Growth Factor (EGF)-like Domain by the Heparin-binding Domain of Heparin-binding EGF-like Growth Factor,
The Journal of Biological Chemistry, Vol.279, No.45, 47335-47343, 2004.
(DOI: 10.1074/jbc.M408556200,   PubMed: 15331606,   CiNii: 80017019313)
16. Takashi Sakai, Li Liu, Xichuan Teng, Rika Mukai-Sakai, Hidenori Shimada, Ryuji Kaji, Tasuku Mitani, Mitsuru Matsumoto, Kazunori Toida, Kazunori Ishimura, Yuji Shishido, Tak W. Mak and Kiyoshi Fukui :
Nucling Recruits Apaf-1/Pro-caspase-9 Complex for the Induction of Stress-Induced Apoptosis,
The Journal of Biological Chemistry, Vol.279, No.39, 41131-41140, 2004.
(DOI: 10.1074/jbc.M402902200,   PubMed: 15271982,   CiNii: 80016958432)
17. Takashi Sakai, Li Liu, Yuji Shishido and Kiyoshi Fukui :
Identification of a Novel, Embryonal Carcinoma Cell-Associated Molecule, Nucling, That Is Up-regulated during Cardiac Muscle Differentiation,
The Journal of Biochemistry, Vol.133, No.4, 429-436, 2003.
(DOI: 10.1093/jb/mvg056,   PubMed: 12761289)
18. Atsuhiko Suzue, Shinji Nagahiro, Yoshiteru Urai, Osamu Jinnouchi, Tokujiro Kanamori, Kyung Tak Kwak, Hwan Ki Park, Tomoya Kawazoe, Sayaka Ichise, Yuji Shishido, Yumiko Tomita, Takashi Sakai and Kiyoshi Fukui :
Astroglial expression of D-amino acid oxidase gene,
Flavins and Flavoproteins 2002, 853-856, 2002.
19. Hidetoshi Hasuwa, Yuji Shishido, Ayano Yamazaki, Terukazu Kobayashi, Xiaochun Yu and Mekada Eisuke :
CD9 Amino Acids Critical for Upregulation of Diphtheria Toxin Binding,
Biochemical and Biophysical Research Communications, Vol.289, No.3, 782-790, 2001.
(DOI: 10.1006/bbrc.2001.6053,   PubMed: 11735113,   Elsevier: Scopus)
20. Tokujiro Kanamori, Mariko Obayashi, Osamu Jinnouchi, Kazuya Kanda, Yoshiteru Urai, Yuji Shishido, Atsuhiko Suzue, Takashi Sakai and Kiyoshi Fukui :
Gene Expression of D-Amino Acid Oxidase in Nervous System,
Flavins and Flavoproteins 1999, 887-890, 1999.
21. Tetsushi Kagawa, Eisuke Mekada, Yuji Shishido and Kazuhiro Ikenaka :
Immune System-related CD9 Is Expressed in Mouse Central Nervous System Myelin at a Very Late Stage of Myelination,
Journal of Neuroscience Research, Vol.50, No.2, 312-320, 1997.
22. Toshihide Mitamura, Toshiyuki Umata, Fumie Nakano, Yuji Shishido, Tetsuro Toyoda, Akiko Itai, Hiroshi Kimura and Eisuke Mekada :
Structure-function Analysis of the Diphtheria Toxin Receptor Toxin Binding Site by Site-directed Mutagenesis,
The Journal of Biological Chemistry, Vol.272, No.43, 27084-27090, 1997.
23. Yuji Shishido, Kailash D. Sharma, Shigeki Higashiyama, Michael Klagsbrun and Eisuke Mekada :
Heparin-like Molecules on the Cell Surface Potentiate Binding of Diphtheria Toxin to the Diphtheria Toxin Receptor/Membrane-anchored Heparin-binding Epidermal Growth Factor-like Growth Factor.,
The Journal of Biological Chemistry, Vol.270, No.49, 29578-29585, 1995.

Academic Paper (Unrefereed Paper):

1. Kiyoshi Fukui, Yuji Shishido, Kazuko YORITA and Takashi Sakai :
Pathophysiological Basis of D-Amino Acid Metabolizing Enzyme : Susceptibility to Schizophrenia and D-Amino Acid Oxidase,
BIO INDUSTRY, Vol.31, No.3, 11-16, 2014.
(CiNii: 40020015241)
2. Koji Ono, Yuji Shishido, Hwan Ki Park, Rabab Mohamed Abou EL-Magd, Seongpil Chung, Kazuko YORITA, Nobuya Sano, Arima Kunimasa, Takashi Sakai, Kazunori Ishimura and Kiyoshi Fukui :
統合失調症におけるD-アミノ酸酸化酵素の病態生理学的役割:ヒトおよびラット脳内における組織化学的発現解析,
ビタミン, Vol.86, No.7, 395-397, 2012.
(CiNii: 110009480124)

Review, Commentary:

1. 目加田 英輔, Yuji Shishido and Kailash D. Sharma :
Diphtheria toxin receptor complex,
Nihon Saikingaku Zasshi, Vol.51, No.3, 853-862, Jul. 1996.

Proceeding of International Conference:

1. Yuji Shishido, Soo Hyeon Kim, Hirofumi Sogabe, Wanitcha Rachadech, Kazuko YORITA, Yusuke Kato and Kiyoshi Fukui :
AGE- AND GENDER-DEPENDENT D-AMINO ACID OXIDASE ACTIVITY IN MOUSE NERVOUS SYSTEM AND PERIPHERAL TISSUES: IMPLICATION FOR AGING AND NEURODEGENERATION,
The 4th International Conference of D-Amino Acid Research, Tokyo, Sep. 2019.
2. Yusuke Kato, Nobuo Maita, Taiki Kohiki, Sumire Kurosawa, Yusuke Nishikawa, Ikuko Sagawa, Masaya Denda, Tsubasa Inokuma, Yuji Shishido, Kazuko YORITA, Akira Shigenaga, Akira Otaka and Kiyoshi Fukui :
Combined approach of computation and enzymology to investigate novel D-amino acid oxidase inhibitors,
The 13th International Symposium of the Institute Network for Biomedical Sciences joint with the 3rd Symposium of the Inter-University Research Network for Trans-Omics Medicine and the 28th Hot Spring Harbor Symposium, Fukuoka, Oct. 2018.
3. Yusuke Kato, Taiki Kohiki, Yusuke Nishikawa, Ikuko Sagawa, Masaya Denda, Tsubasa Inokuma, Yuji Shishido, Akira Shigenaga, Akira Otaka and Kiyoshi Fukui :
Studies on binding molecules to D-amino acid oxidase using computational approaches,
The 12th International Symposium of the Institute Network, Tokyo, Nov. 2017.
4. Kiyoshi Fukui, Hong Diem Tran, Hirofumi Sogabe, Hyeon Soo Kim, Trinh Thanh Thi Huong, Anh Tuan Pham, Yuji Shishido, Kazuko YORITA and Yusuke Kato :
Translational enzymology on D-amino acid metabolism,
The 3rd International Conference of D-Amino Acid Research, Varese, Jul. 2017.
5. Hirofumi Sogabe, Yuji Shishido, SooHyeon Kim, Kazuko YORITA, Yusuke Kato and Kiyoshi Fukui :
Regulation of D-amino acid oxidase expression and metabolism in mammalian cells,
The 3rd International Conference of D-Amino Acid Research, Varese, Jul. 2017.
6. Hirofumi Sogabe, Yuji Shishido and Kiyoshi Fukui :
Regulation of D-amino acid oxidase expression in mammalian cells,
11th International Symposium of The Institute Network Frontiers in Biomedical Sciences, Tokushima, Jan. 2017.
7. Kiyoshi Fukui, Hirofumi Sogabe, Soo Hyeon Kim, Hung Thi Thanh Trinh, Tuan Anh Pham, Diem Hong Tran, Yuji Shishido, Kazuko YORITA and Yusuke Kato :
Medical aspects and chiral science of amino acid metabolism: regulation of human D-amino acid oxidase gene expression and implication for translation to neuropsychiatric disorders,
The Fifth International Conference on Cofactors and Active Enzyme Molecule 2016, Kurobe, Sep. 2016.
8. Huy Van Dang, Takashi Sakai, Tuan Anh Pham, Diem Hong Tran, Kazuko YORITA, Yuji Shishido and Kiyoshi Fukui :
A novel apoptosis associated protein, Nucling Controls Mammary Gland Involution by Regulating NF-B and STAT3: Implication for the pathogenesis of breast cancer,
Inaugural Symposium Biochemistry: Towards Academic Excellence, Boralesgamuwa, Jun. 2016.
9. Huy Van Dang, Takashi Sakai, Tuan Anh Pham, Diem Hong Tran, Kazuko YORITA, Yuji Shishido and Kiyoshi Fukui :
Nucling, a Novel Apoptosis-associated Protein, Controls Mammary Gland Involution by Regulating NF-B and STAT3,
1st International Symposium on Molecular Medicine in Tokushima University, Tokushima, Dec. 2015.
10. Kiyoshi Fukui, Diem Hong Tran, Huy Van Dang, Huong Thi Thanh Trinh, Tuan Anh Pham, Hirofumi Sogabe, Soo Hyeon Kim, Takanaga Ako, Yuji Shishido, Kazuko YORITA, Yusuke Kato and Takashi Sakai :
Chiral Science and Pathophysiology of Amino Acid Metabolism: regulation of human D-amino acid oxidase gene expression and implication for human psychiatric disorders.,
14th FAOBMB Congress and 84th Annual Meeting of SBC (I), Hyderabad, Nov. 2015.
11. Huy Van Dang, Takashi Sakai, Tuan Anh Pham, Diem Hong Tran, Kazuko YORITA, Yuji Shishido and Kiyoshi Fukui :
Nucling, a novel apoptosis-associated protein, controls postlactational involution of mammary gland through regulation of NF-B and STAT3,
The 2nd GENE AND IMMUNOTHERAPY CONFERENCE in VIETNAM, Ho Chi Minh, Sep. 2015.
12. Diem Hong Tran, Yuji Shishido, Seongpil Chung, Huong Thi Thanh Trinh, Kazuko YORITA, Takashi Sakai and Kiyoshi Fukui :
Search for the regulation of human D-amino acid oxidase gene, a potential risk factor of schizophrenia,
The 2nd GENE AND IMMUNOTHERAPY CONFERENCE in VIETNAM, Ho Chi Minh, Sep. 2015.
13. Huy Van Dang, Takashi Sakai, Tuan Anh Pham, Diem Hong Tran, Kazuko YORITA, Yuji Shishido and Kiyoshi Fukui :
Nucling, an apoptosis-associated novel protein, controls mammary gland involution through regulation of NF-B and STAT3,
The 10th International Symposium of the Institute Network, Sapporo, Jul. 2015.
(DOI: 10.1074/jbc.M115.673848,   PubMed: 26269594)
14. Kiyoshi Fukui, Diem Hong Tran, Huy Van Dang, Huong Thi Thanh Trinh, Tuan Anh Pham, Hirofumi Sogabe, Soo Hyeon Kim, Takanaga Ako, Yuji Shishido, Kazuko YORITA, Yusuke Kato and Takashi Sakai :
Chiral science of amino acid metabolism and implication to pathophysiology of schizophrenia,
40th Annual Conference of the Malaysian Society for Biochemistry & Molecular Biology, Kuala Lumpur, Jun. 2015.
15. Kiyoshi Fukui, Yoshiteru Urai, Hwan Ki Park, Tomoya Kawazoe, Sanae Iwana, Koji Ono, Rabab Mohamed Abou El-Magd, Seongpil Chung, Salah Mohamed El-Sayed, Diem Hong Tran, Hirofumi Sogabe, Takanaga Ako, Yuji Shishido, Kazuko YORITA and Takashi Sakai :
D-AMINO ACID METABOLISM IN HEALTH AND DISEASES: PATHOPHYSIOLOGICAL BASES FOR SCHIZOPHRENIA AND CANCER GENE THERAPY,
The 2nd International Conference of D-Amino Acid Research, Utsunomiya, Sep. 2014.
16. Diem Hong Tran, Yuji Shishido, Huong Thi Thanh Trinh, Kazuko YORITA, Takashi Sakai and Kiyoshi Fukui :
Identification of promoter region of human D-amino acid oxidase (hDAO) gene and its interacting proteins - Search for the regulation of hDAO expression,
The 9th International Symposium of the Institute Network, Suita, Jun. 2014.
17. Kiyoshi Fukui, Yoshiteru Urai, Hwan Ki Park, Tomoya Kawazoe, Sanae Iwana, Koji Ono, Rabab Mohamed Abou El-Magd, Seongpil Chung, Salah Mohamed El-Sayed, Diem Hong Tran, Yuji Shishido, Kazuko YORITA and Takashi Sakai :
Medical Aspects of D-Amino Acid Metabolism: Molecular Target for Cancer Gene Therapy and Schizophrenia,
FAOBMB Mini-Symposium Molecular Bases for Medical and Pharmaceutical Sciences, Yahaba, Apr. 2013.
18. Kiyoshi Fukui, Yoshiteru Urai, Hwan Ki Park, Tomoya Kawazoe, Sanae Iwana, Koji Ono, Rabab Mohamed Abou El-Magd, Seongpil Chung, Salah Mohamed El-Sayed, Diem Hong Tran, Yuji Shishido, Kazuko YORITA and Takashi Sakai :
Medical Aspects of D-Amino Acid Metabolism: Molecular Target for Cancer Gene Therapy and Schizophrenia,
The 1st GENE AND IMMUNOTHERAPY CONFERENCE, Ho Chi Minh, Mar. 2013.
19. Kiyoshi Fukui, Salah Mohamed El-Sayed, Rabab Mohamed Abou El-Magd, Yuji Shishido, Seongpil Chung, Diem Hong Tran and Takashi Sakai :
Oxidative Stress-Energy Deplation Therapy as a New Treatment Modality for Glioma,
Miami 2013 Winter Symposium: The Molecular Basis of Metabolism and Nutrition, Miami, Feb. 2013.
20. Kiyoshi Fukui, Tomoya Kawazoe, Sanae Iwana, Rabab Mohamed Abou El-Magd, Koji Ono, Seongpil Chung, Salah Mohamed El-Sayed, Kumiko Shinohara, Diem Hong Tran, Yuji Shishido, Kazuko YORITA and Takashi Sakai :
Modulation of D-amino acid oxidase activity as a novel strategy for the treatment of psychiatric disorders,
Function and dysfunction of D-amino acids in the central nervous system, Tokyo, Sep. 2011.
21. Kiyoshi Fukui, Koji Ono, Rabab Mohamed Abou El-Magd, Sanae Iwana, Tomoya Kawazoe, Seongpil Chung, Ying Song, Yuji Shishido, Kazuko YORITA and Takashi Sakai :
D-amino acid oxidase: pathophysiological basis and molecular target for schizophrenia,
the 12th IUBMB Conference, the 21st FAOBMB Conference and the ComBio2010 meeting, Melbourne, Sep. 2010.
22. Kiyoshi Fukui, Sanae Iwana, Rabab Mohamed Abou El-Magd, Tomoya Kawazoe, Koji Ono, Seongpil Chung, Yuji Shishido, Kazuko YORITA and Takashi Sakai :
Modulation of D-Amino Acid Oxidase Activity as a Novel Strategy for the Treatment of Schizophrenia,
The 1st Meeting of the Asian College of Neuropsychopharmacology, Kyoto, Nov. 2009.
23. Takashi Sakai, HoangNam Tran, Sun Mi Kim, Li Liu, Xichuan Teng, Yuji Shishido, Mukai-Sakai Rika, Mitsuru Matsumoto, Kazunori Ishimura, Yoshio Hayashi, Ryuji Kaji and Kiyoshi Fukui :
Nucling, a novel stress-sensitive protein, regulates NF-kappa B activation,
The 4th International Congress on Stress Responses in Biology and Medicine, The 4th Annual Meeting of the Biomedical Society for Stress Response, Sapporo, Oct. 2009.
24. Kiyoshi Fukui, Sanae Iwana, Rabab Mohamed Abou El-Magd, Tomoya Kawazoe, Koji Ono, Seongpil Chung, Yuji Shishido, Kazuko YORITA and Takashi Sakai :
Modulation of D-amino acid oxidase activity as a novel strategy for the treatment of schinophrenia,
The 1st International Conference of D-amino Acid Research, Awaji, Jul. 2009.
25. Kiyoshi Fukui, Tokujiro Kanamori, Mariko Obayashi, Osamu Jinnouchi, Kazuya Kanda, Yoshiteru Urai, Yuji Shishido, Atsuhiko Suzue and Takashi Sakai :
Gene Expression of D-Amino Acid Oxidase in Nervous System,
The 13th International Congress on Flavins and Flavoproteins, Konstanz, Aug. 1999.

Proceeding of Domestic Conference:

1. SooHyeon Kim, Yuji Shishido, Hirofumi Sogabe, Wanitcha Rachadech, Kazuko YORITA, Yusuke Kato and Kiyoshi Fukui :
マウス脳および末梢組織における年齢および性別依存的D-アミノ酸酸化酵素活性:加齢および神経変性への影響について,
The 92nd Annual Meeting of the Japanese Biochemical Society, Sep. 2019.
2. Bunrin Rin, Hirofumi Sogabe, Yuji Shishido, Kiyoshi Fukui, Kiyoshi Fukui and Takashi Sakai :
新規NF-κB制御分子ヌクリングはインスリンの発現制御に関与している,
The 91st Annual Meeting of the Japanese Biochemical Society, Sep. 2018.
3. SooHyeon Kim, Yuji Shishido, Hirofumi Sogabe, Rachadech Wanitcha, Kazuko YORITA, Yusuke Kato and Kiyoshi Fukui :
Distribution of D-amino acid oxidase activity in mouse brain regions and peripheral tissues examined by enzyme-coupled colorimetric assay,
The 91st Annual Meeting of the Japanese Biochemical Society, Sep. 2018.
4. Yuji Shishido, Hirofumi Sogabe, SooHyeon Kim, Rachadech Wanitcha, Yusuke Kato and Kiyoshi Fukui :
アストログリアにおける自然免疫系によるD-アミノ酸酸化酵素遺伝子の発現調節,
The 91st Annual Meeting of the Japanese Biochemical Society, Sep. 2018.
5. Yuji Shishido, Hirofumi Sogabe, Hyeon Soo Kim, Rachadech Wanitcha, Yusuke Kato and Kiyoshi Fukui :
自然免疫とヒト D-アミノ酸酸化酵素遺伝子の発現調節機構,
第14回 D-アミノ酸研究会学術講演会, Sep. 2018.
6. Hirofumi Sogabe, Yuji Shishido, SooHyeon Kim, Wanitcha Rachadech, Kazuko YORITA, Yusuke Kato and Kiyoshi Fukui :
哺乳動物細胞におけるD-アミノ酸酸化酵素タンパク質の代謝経路の解析,
2017年度生命科学系学会合同年次大会, Dec. 2017.
7. Yuji Shishido, Hirofumi Sogabe, SooHyeon Kim, Wanitcha Rachadech, Kazuko YORITA, Yusuke Kato and Kiyoshi Fukui :
ミクログリアにおけるD-アミノ酸酸化酵素遺伝子の発現調節機構の解明,
2017年度生命科学系学会合同年次大会, Dec. 2017.
8. Yusuke Kato, Taiki Kohiki, Yusuke Nishikawa, Ikuko Sagawa, Masaya Denda, Tsubasa Inokuma, Yuji Shishido, Akira Shigenaga, Akira Otaka and Kiyoshi Fukui :
DAO分子表面に結合する阻害分子の計算科学的解析,
2017年度生命科学系学会合同年次大会, Dec. 2017.
9. Hirofumi Sogabe, Yuji Shishido, Soo Hyeon Kim, Kazuko YORITA, Yusuke Kato and Kiyoshi Fukui :
哺乳動物細胞におけるD-アミノ酸酸化酵素タンパク質の代謝経路の解析,
日本ビタミン学会第69回大会, Jun. 2017.
10. Yuji Shishido, Huong Thi Thanh Trinh, Soo Hyeong Kim, Hirofumi Sogabe, Kazuko YORITA, Yusuke Kato and Kiyoshi Fukui :
グリア細胞におけるヒトD-アミノ酸酸化酵素遺伝子の発現誘導機構の解明,
第89回日本生化学会大会, Sep. 2016.
11. Yuji Shishido, Yuta Isomura, Hiroya Matsuda, Huong Thi Thanh Trinh, Soo Hyeong Kim, Hirofumi Sogabe, Kazuko YORITA, Yusuke Kato and Kiyoshi Fukui :
ヒトD-アミノ酸酸化酵素遺伝子の発現調節機構と炎症反応,
第12回D-アミノ酸学会学術講演会, Sep. 2016.
12. Huong Thi Thanh Trinh, Yuji Shishido, Diem Hong Tran, Hirofumi Sogabe, Soo Hyeon Kim and Kiyoshi Fukui :
Regulation of gene expression of mouse D-amino acid oxidase,
第57回日本生化学会 中国四国支部例会, May 2016.
13. Hirofumi Sogabe, Takanaga Ako, Yuji Shishido, Diem Hong Tran, Huong Thi Thanh Trinh, Kazuko YORITA, Yusuke Kato and Kiyoshi Fukui :
低栄養ストレスによる D-アミノ酸酸化酵素タンパク質の動的変化,
第57回日本生化学会 中国四国支部例会, May 2016.
14. Yuji Shishido, Diem Hong Tran, Soo Hyeon Kim, Huong Thi Thanh Trinh, Hirofumi Sogabe, Takanaga Ako, Kazuko YORITA, Yusuke Kato and Kiyoshi Fukui :
ヒト細胞におけるD-アミノ酸酸化酵素遺伝子の発現調節機構,
第38回日本分子生物学会年会,第88回日本生化学会大会 合同大会, Dec. 2015.
15. Kiyoshi Fukui, Diem Hong Tran, Yuji Shishido, Huong Thi Thanh Trinh, Tuan Anh Pham, Hirofumi Sogabe, Soo Hyeon Kim, Takanaga Ako, Kazuko YORITA and Yusuke Kato :
アミノ酸代謝のキラルサイエンスと統合失調症病態システム酵素学,
第38回日本分子生物学会年会,第88回日本生化学会大会 合同大会, Dec. 2015.
16. Yuji Shishido, Diem Hong Tran, Huong Thi Thanh Trinh, Soo Hyoen Kim, Kazuko YORITA, Yusuke Kato and Kiyoshi Fukui :
哺乳動物における D-アミノ酸酸化酵素遺伝子の発現誘導機構の解析,
第 11 回 D-アミノ酸学会学術講演会, Aug. 2015.
17. Diem Hong Tran, Yuji Shishido, Seongpil Chung, Huong Thi Thanh Trinh, Kazuko YORITA, Takashi Sakai and Kiyoshi Fukui :
ヒトD-アミノ酸酸化酵素遺伝子の発現調節機構:2つのプロモーター領域の同定とその調節,
日本ビタミン学会第67回大会, Jun. 2015.
18. Kazuko YORITA, Sumire Kurosawa, Yuji Shishido, Shigeki Sano, Yoshiki Kashiwada, Noriaki Minakawa and Kiyoshi Fukui :
ヒト由来D-アミノ酸酸化酵素のエフェクター探索のためのハイスループットクリーニングと構造機能相関,
第56回日本生化学会 中国四国支部例会, May 2015.
19. Hirofumi Sogabe, Takanaga Ako, Yuji Shishido, Diem Hong Tran, Huong Thi Thanh Trinh, Kazuko YORITA, Yusuke Kato and Kiyoshi Fukui :
腎臓近位尿細管様細胞におけるD-アミノ酸酸化酵素の発現調節機構の解析,
第56回日本生化学会 中国四国支部例会, May 2015.
20. Huy Van Dang, Takashi Sakai, Tuan Anh Pham, Diem Hong Tran, Kazuko YORITA, Yuji Shishido and Kiyoshi Fukui :
Nucling an apoptosis-associated novel protein, controls the postlactational involution of mammary gland through regulation of NF-B and STAT3,
The 87th Annual Meeting of the Japanese Biochemical Society, Oct. 2014.
21. Yuji Shishido, Kana Morimoto, Diem Hong Tran, Huong Thi Thanh Trinh, Hirofumi Sogabe, Takanaga Ako, Kazuko YORITA and Kiyoshi Fukui :
哺乳動物の中枢神経系におけるDーアミノ酸酸化酵素遺伝子発現誘導機構,
The 87th Annual Meeting of the Japanese Biochemical Society, Oct. 2014.
22. Diem Hong Tran, Yuji Shishido, Huong Thi Thanh Trinh, Kazuko YORITA, Takashi Sakai and Kiyoshi Fukui :
Induction and regulation of gene expression of D-amino acid oxidase in glial and kidney cells,
日本ビタミン学会第66回大会, Jun. 2014.
23. Takashi Sakai, Yukiya Sako, Yuki Honjo, Kota Nakajima, Huy Van Dang, Tuan Anh Pham, Yuji Shishido, Kazuko YORITA and Kiyoshi Fukui :
新規アポトーシス誘導因子ヌクリングのホモシステイン代謝系及び神経精神疾患への関与の検討,
日本ビタミン学会第66回大会, Jun. 2014.
24. Kana Morimoto, Yuji Shishido, Diem Hong Tran, Huong Thi Thanh Trinh, Hirofumi Sogabe, Kazuko YORITA and Kiyoshi Fukui :
中枢神経系におけるD-アミノ酸酸化酵素遺伝子の発現誘導機構の解析,
第55回日生化学会 中国四国支部例会, Jun. 2014.
25. Huy Van Dang, Takashi Sakai, Tuan Anh Pham, Diem Hong Tran, Kazuko YORITA, Yuji Shishido and Kiyoshi Fukui :
Loss of Nucling promotes delayed mammary gland involution through suppression of NF-B and STAT3,
第55回日生化学会 中国四国支部例会, Jun. 2014.
26. Yuji Shishido, Kana Morimoto, Diem Hong Tran, Huong Thi Thanh Trinh, Hirofumi Sogabe, Kazuko YORITA and Kiyoshi Fukui :
Analysis of the regulatory mechanism of mammalian D-amino acid oxidase gene expression,
The 86th Annual Meeting of the Japanese Biochemical Society, Sep. 2013.
27. Huy Van Dang, Takashi Sakai, Tuan Anh Pham, Diem Hong Tran, Kazuko YORITA, Yuji Shishido and Kiyoshi Fukui :
Delayed mammary gland involution in Nucling-KO mice,
The 86th Annual Meeting of the Japanese Biochemical Society, Sep. 2013.
28. Diem Hong Tran, Yuji Shishido, Huong Thi Thanh Trinh, Kazuko YORITA, Takashi Sakai and Kiyoshi Fukui :
Induction and regulation of gene expression of D-amino acid oxidase in LLC-PK1 cells,
The 86th Annual Meeting of the Japanese Biochemical Society, Sep. 2013.
29. Diem Hong Tran, Yuji Shishido, Huong Thi Thanh Trinh, Kazuko YORITA, Takashi Sakai and Kiyoshi Fukui :
Induction and regulation of gene expression of D-amino acid oxidase in LLC-PK1 cells,
第9回 D-アミノ酸研究会学術講演会, Sep. 2013.
30. Diem Hong Tran, Yuji Shishido, Kazuko YORITA, Takashi Sakai and Kiyoshi Fukui :
Induction and regulation of gene expression of in LLC-PK1 cells,
第54回日本生化学会 中国四国支部例会, Jun. 2013.
31. Diem Hong Tran, Yuji Shishido, Seongpil Chung, Kazuko YORITA, Takashi Sakai and Kiyoshi Fukui :
Induction and regulation of gene expression of D-amino acid oxidase in LLC-PK1 cells,
The 85th Annual Meeting of the Japanese Biochemical Society, Dec. 2012.
32. Yuji Shishido, Diem Hong Tran, Kana Morimoto, Seongpil Chung, Kazuko YORITA, Takashi Sakai and Kiyoshi Fukui :
Regulation of gene expression of D-amino acid oxidase in glial cells,
The 85th Annual Meeting of the Japanese Biochemical Society, Dec. 2012.
33. Kiyoshi Fukui, Salah Mohamed El-Sayed, Rabab Mohamed Abou El-Magd, Yuji Shishido, Seongpil Chung, Diem Hong Tran and Takashi Sakai :
Oxidative stress-energy depletion therapy as a new treatment modality for cancer,
日本ビタミン学会第64回大会, Jun. 2012.
34. Seongpil Chung, Yuji Shishido, Kazuko YORITA, Takashi Sakai and Kiyoshi Fukui :
D-アミノ酸酸化酵素関連遺伝子の発現に関するマイクロアレイ並びにプロテオミクス解析,
日本ビタミン学会第64回大会, Jun. 2012.
35. Seongpil Chung, Diem Hong Tran, Kazuko YORITA, Yuji Shishido, Takashi Sakai and Kiyoshi Fukui :
アストログリア細胞におけるD-セリン代謝産物ヒドロキシピルビン酸の細胞死誘導活性,
第53回日本生化学会 中国・四国支部例会, May 2012.
36. Kiyoshi Fukui, rabab Mohamed Abou El-Magd, Seongpil Chung, Salah Mohamed El-Sayed, Diem Hong Tran, Kumiko Shinohara, Yuji Shishido, Kazuko YORITA and Takashi Sakai :
D-アミノ酸代謝システムの活性制御による新規精神神経疾患治療戦略,
The 84th Annual Meeting of the Japanese Biochemical Society, Sep. 2011.
37. Salah Mohamed El-Sayed, Rabab Mohamed Abou El-Magd, Yuji Shishido, Seongpil Chung, Kazuko YORITA, Takashi Sakai, Hiroyoshi Watanabe, Shoji Kagami and Kiyoshi Fukui :
Combination of oxidative stress and energy depletion induced significant glioma cell death,
The 84th Annual Meeting of the Japanese Biochemical Society, Sep. 2011.
38. Yuji Shishido, Ying Song, Kumiko Shinohara, Diem Hong Tran, Kazuko YORITA, Takashi Sakai and Kiyoshi Fukui :
ヒトD-アミノ酸酸化酵素のグリア細胞内における機能解析,
The 84th Annual Meeting of the Japanese Biochemical Society, Sep. 2011.
39. Salah Mohamed El-Sayed, Rabab Mohamed Abou El-Magd, Yuji Shishido, Seongpil Chung, Takashi Sakai, Hiroyoshi Watanabe, Shoji Kagami and Kiyoshi Fukui :
D-アミノ酸酸化酵素の遺伝子導入により,グリオーマ細胞では,3-ブロモピル ビン酸の解糖系への阻害作用が増強される,
第7回 D-アミノ酸研究会学術講演会, Sep. 2011.
40. Seongpil Chung, Ying Song, Hwan Ki Park, Yuji Shishido, Kazuko YORITA, Takashi Sakai and Kiyoshi Fukui :
アストログリア細胞内の D-アミノ酸酸化酵素により D-セリンから産生されるヒ ドロキシピルビン酸の細胞死誘導活性,
第7回 D-アミノ酸研究会学術講演会, Sep. 2011.
41. Yuji Shishido, Ying Song, Kumiko Shinohara, Rabab Mohamed Abou El-Magd, Diem Hong Tran, Kazuko YORITA, Takashi Sakai and Kiyoshi Fukui :
グリア細胞における D‒アミノ酸酸化酵素の機能解析,
第7回 D-アミノ酸研究会学術講演会, Sep. 2011.
42. Kiyoshi Fukui, Tomoya Kawazoe, Sanae Iwana, Rabab Mohamed Abou El-Magd, Koji Ono, Seongpil Chung, Salah Mohamed EL-Sayed, Kumiko Shinohara, Yuji Shishido, Kazuko YORITA and Takashi Sakai :
D-アミノ酸酸化酵素の活性制御による新規精神神経疾患治療戦略,
第7回 D-アミノ酸研究会学術講演会, Sep. 2011.
43. Salah Mohamed El-Sayed, Rabab Mohamed Abou El-Magd, Yuji Shishido, Seongpil Chung, Kazuko YORITA, Takashi Sakai, Hiroyoshi Watanabe, Shoji Kagami and Kiyoshi Fukui :
D-amino acid oxidase gene therapy sensitizes glioma cells to the anti-glycolytic effect of 3-bromopyruvate,
第52回 日本生化学会中国・四国支部例会・シンポジウム, May 2011.
44. Salah El-Sayed Mohamed, Rabab Mohamed Abou El-Magd, Yuji Shishido, Seongpil Chung, Kazuko YORITA, Takashi Sakai and Kiyoshi Fukui :
DAO gene therapy sensitizes glioma cell selectively to anti-glycolytic effect of 3-bromopyruvate,
日本農芸化学会中四国支部第29回講演会 日本ビタミン学会中国・四国地区第1回講演会 合同講演会, Jan. 2011.
45. Seongpil Chung, Ying Song, Ki Hwan Park, Kazuko YORITA, Yuji Shishido, Takashi Sakai and Kiyoshi Fukui :
D-セリン代謝産物ヒドロキシピルビン酸の細胞死誘導活性,
日本農芸化学会中四国支部第29回講演会 日本ビタミン学会中国・四国地区第1回講演会 合同講演会, Jan. 2011.
46. Seongpil Chung, Kimiko Sogabe, Hwan Ki Park, Ying Song, Koji Ono, Rabab Mohamed Abou El-Magd, Yuji Shishido, Kazuko YORITA, Takashi Sakai and Kiyoshi Fukui :
Potential cytotoxic effect of hydroxypyruvate produced from D-serine by astroglial D-amino acid oxidase,
第33回日本分子生物学会年会・第83回日本生化学会大会 合同大会, Dec. 2010.
47. Salah El-Sayed M., Rabab Abou El-Magd Mohamed, Yuji Shishido, Seongpil Chung, Kazuko YORITA, Takashi Sakai, Hiroyoshi Watanabe, Shoji Kagami and Kiyoshi Fukui :
D-amino acid oxidase gene therapy sensitizes glioma cells selectively to the anti-glycolytic effect of 3-bromopyruvate,
第33回日本分子生物学会年会・第83回日本生化学会大会 合同大会, Dec. 2010.
48. Koji Ono, Yuji Shishido, Hwan Ki Park, Rabab Mohamed Abou El-Magd, Seongpil Chung, Kazuko YORITA, Nobuya Sano, Arima Kunimasa, Takashi Sakai, Kazunori Ishimura and Kiyoshi Fukui :
脈絡叢におけるD-アミノ酸酸化酵素発現の病態生理学的役割:ヒトおよびラット脳におけるRNA並びにタンパク質レベルでの解析,
日本ビタミン学会第62回大会, Jun. 2010.
49. Seongpil Chung, Ying Song, Hwan Ki Park, Sogabe Kimiko, Koji Ono, Mohamed Abou El-Magd Rabab, Kazuko YORITA, Yuji Shishido, Takashi Sakai and Kiyoshi Fukui :
アストログリア細胞内のD-セリン代謝システムにおけるD-アミノ酸酸化酵素の役割及び代謝産物の細胞死誘導活性,
日本ビタミン学会第62回大会, Jun. 2010.
50. Ying Song, Seongpil Chung, Rabab Mohamed Abou El-Magd, Kazuko YORITA, Yuji Shishido, Takashi Sakai and Kiyoshi Fukui :
D-セリン代謝システムにおける D-アミノ酸酸化酵素の役割及び代謝産物の細胞毒性,
第51回日本生化学会中国四国支部例会, May 2010.
51. Koji Ono, Yuji Shishido, Hwan Ki Park, Rabab Mohamed Abou EL-Magd, Seongpil Chung, Kazuko YORITA, Nobuya Sano, Arima Kunimasa, Takashi Sakai and Kiyoshi Fukui :
Potential pathophysiological role of D-amino acid oxidase in schizophrenia: immunohistochemical and in situ hybridization studies on the expression in human and rat brain,
The 82nd annual meeting of the Japanese Biochemical Society, Oct. 2009.
52. Kiyoshi Fukui, Sanae Iwana, Rabab Mohamed abou El-Magd, Tomoya Kawazoe, Koji Ono, Seongpil Chung, Yuji Shishido, Kazuko YORITA and Takashi Sakai :
Modulation of D-amino acid oxidase: novel mechanism for the action of anti-schizophrenic drugs,
The 82nd annual meeting of the Japanese Biochemical Society, Oct. 2009.
53. Koji Ono, Yuji Shishido, Park Ki Hwan, El-Magd Mohamed Abou Rabab, Seongpil Chung, Kazuko YORITA, Nobuya Sano, Arima Kunimasa, Takashi Sakai, Kazunori Ishimura and Kiyoshi Fukui :
免疫組織化学と in situ hybridization 法を用いたヒトおよびラット脳における D-アミノ酸酸化酵素の発現解析,
第50回日本組織細胞化学会総会・学術集会, Sep. 2009.
54. Koji Ono, Yuji Shishido, 朴 煥埼, Rabab Mohamed Abou El-Magd, Seongpil Chung, Kazuko YORITA, Nobuya Sano, 有馬 邦正, Takashi Sakai, Kazunori Ishimura and Kiyoshi Fukui :
免疫組織化学とin situ hybridization法を用いたヒトおよびラット脳におけるD- アミノ酸酸化酵素の発現解析,
第50回日本組織細胞化学会総会・学術集会, Sep. 2009.
55. Seongpil Chung, Hwan Ki Park, Koji Ono, Rabab Mohamed Abou El-Magd, Yuji Shishido, Kazuko YORITA, Takashi Sakai and Kiyoshi Fukui :
Genomic and proteomic analysis of rat glioma cells overexpressing D-amino acid oxidase and stimulated with D-serine,
日本ビタミン学会第61回大会, May 2009.
56. Yuji Shishido, Seongpil Chung, Hwan Ki Park, Takashi Sakai and Kiyoshi Fukui :
D-アミノ酸酸化酵素のグリア細胞特異的発現,
50回日本生化学会中国四国支部例会, May 2009.
57. Koji Ono, Hwan Ki Park, Rabab Mohamed Abou El-Magd, Seongpil Chung, Yuji Shishido, Kazuko YORITA, Takashi Sakai and Kiyoshi Fukui :
脳内におけるD-アミノ酸酸化酵素遺伝子の発現:ヒトおよびラット脳におけるRNA並びにタンパク質レベルでの解析,
第31回日本分子生物学会年会・第81回日本生化学会大会合同大会, Dec. 2008.
58. Seongpil Chung, Hwan Ki Park, Koji Ono, Rabab M. Abou El-Magd, Yuji Shishido, Kazuko YORITA, Takashi Sakai and Kiyoshi Fukui :
Proteomic and genomic analyses of rat glioma cells overexpressing D-amino acid oxidase,
第31回日本分子生物学会年会・第81回日本生化学会大会合同大会, Dec. 2008.
59. Seongpil Chung, Hwan Ki Park, Koji Ono, Rabab Mohamed Abou El-Magd, Kazuko YORITA, Yuji Shishido, Takashi Sakai and Kiyoshi Fukui :
脳内D-セリン代謝システムにおけるD-アミノ酸酸化酵素の役割及び代謝産物の細胞死誘導活性,
第4回D-アミノ酸研究会学術講演会, Sep. 2008.
60. Takashi Sakai, Li Liu, Rika Sakai, Ryuji Kaji, Tasuku Mitani, Mitsuru Matsumoto, Kazunori Toida, Yuji Shishido and Kiyoshi Fukui :
Nucling is important for the upregulation of Apaf-1/procaspase-9cytochrome c apoptosome following cellular stress in vivo,
The 77th Annual Meeting of the Japanese Biochemical Society, Oct. 2004.
61. Takashi Sakai, Li Liu, Yuji Shishido, Ryuji Kaji and Kiyoshi Fukui :
Identification of a Novel, Embryonal Carcinoma Cell-Associated Molecule, Nucling, That is Up-regulated during Cardiac Muscle Differentiation,
The 77th Annual Meeting of the Japanese Biochemical Society, Oct. 2004.

Et cetera, Workshop:

1. SooHyeon Kim, Yuji Shishido, Hirofumi Sogabe, Wanitcha Rachadech, Yusuke Kato and Kiyoshi Fukui :
生体内各組織におけるD-アミノ酸酸化酵素活性の検出とその生理的意義の考察,
第454回研究協議会, Oct. 2018.
2. Kiyoshi Fukui, Yuji Shishido, Diem Hong Tran, Huong Thi Thanh Trinh, Soo Hyeon Kim, Hirofumi Sogabe, Kazuko YORITA and Yusuke Kato :
D-アミノ酸酸化酵素遺伝子の発現調節機構の解析による統合失調症胎児期起源仮説の考察,
第444回ビタミンB研究協議会, Jun. 2016.
3. Yuji Shishido, Diem Hong Tran, Kana Morimoto, Huong Thi Thanh Trinh, Hirofumi Sogabe, Kazuko YORITA, Takashi Sakai and Kiyoshi Fukui :
遺伝子発現調節から探るグリア・ニューロン連関の病態システム酵素学,
第433回ビタミンB研究協議会, Aug. 2013.
4. Yuji Shishido :
培養グリア細胞におけるD-アミノ酸酸化酵素の遺伝子発現および酵素活性調節機構,
第29回 Neuroscience Seminar Tokushima, Mar. 2013.

Grants-in-Aid for Scientific Research (KAKEN Grants Database @ NII.ac.jp)