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Tokushima UniversityGraduate School of Biomedical Sciences歯学域Oral ScienceBasic DentistryDepartment of Oral Bioscience
Tokushima UniversityFaculty of DentistryCourse in DentistryBasic Oral SciencesOral Bioscience
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Research

Personal Web Page

Field of Study

Biochemistry, Molecular Biology

Subject of Study

Study on the Inhibition Mechanism of Glycyrrhizin against Phospholipase A2 Activity (carbon tetrachloride, glycyrrhizin, phospholipase) (Carbontetrachloride induces liver cell injury. The fact, this injury is inhibited by phospholipase A2 inhibitor, indicates that phospholipase A2 is included in this process. Because glycyrrhizin inhibits cell injury induced by carbon tetrachloride, it is possible that glycyrrhizin interfere with activity of phospholipase A2. To clarify the inhibition mechanism of glycyrrhizin against cell injury induced by carbontetrachloride, I am studying on the interaction between phospholipase A2 and glycyrrhizin, and gene expression pattern of liver cell treated with carbontetrachloride and/or glycyrrhizin using RT-PCR and microarray method.)

Book / Paper

Book:

1. Taigo Horiguchi, Keiko Miyoshi and Takafumi Noma :
生化学実習書 (第14版1刷),
徳島大学大学院医歯薬学研究部分子医化学分野, Tokushima, May 2020.
2. Taigo Horiguchi, Keiko Miyoshi and Takafumi Noma :
生化学実習書 (第13版1刷),
徳島大学大学院医歯薬学研究部分子医化学分野, Tokushima, May 2019.
3. Taigo Horiguchi, Keiko Miyoshi and Takafumi Noma :
生化学実習書 (第12版1刷),
徳島大学大学院医歯薬学研究部分子医化学分野, Tokushima, May 2018.
4. Taigo Horiguchi, Keiko Miyoshi, Ayako Tanimura and Takafumi Noma :
生化学実習書 (第11版1刷),
徳島大学大学院医歯薬学研究部分子医化学分野, Tokushima, May 2017.
5. Taigo Horiguchi, Keiko Miyoshi, Ayako Tanimura and Takafumi Noma :
生化学実習書 (第10版1刷),
徳島大学大学院医歯薬学研究部分子医化学分野, Tokushima, May 2016.
6. Taigo Horiguchi, Keiko Miyoshi, Ayako Tanimura and Takafumi Noma :
生化学実習書 (第9版1刷),
徳島大学大学院医歯薬学研究部分子医化学分野, Tokushima, May 2015.
7. Taigo Horiguchi, Keiko Miyoshi, Ayako Tanimura and Takafumi Noma :
生化学実習書 (第8版1刷),
徳島大学大学院ヘルスバイオサイエンス研究部分子医化学分野, Tokushima, May 2014.
8. Taigo Horiguchi, Keiko Miyoshi, Ayako Tanimura and Takafumi Noma :
生化学実習書 (第7版1刷),
徳島大学大学院ヘルスバイオサイエンス研究部分子医化学分野, Tokushima, May 2013.
9. Taigo Horiguchi, Keiko Miyoshi, Ayako Tanimura and Takafumi Noma :
生化学実習書 (第6版1刷),
徳島大学大学院ヘルスバイオサイエンス研究部分子医化学分野, Tokushima, May 2012.
10. Taigo Horiguchi, Keiko Miyoshi, Ayako Tanimura and Takafumi Noma :
生化学実習書 (第5版2刷),
徳島大学大学院ヘルスバイオサイエンス研究部分子医化学分野, Tokushima, May 2011.
11. Taigo Horiguchi, Keiko Miyoshi, Taro Muto and Takafumi Noma :
生化学実習書 (第5版1刷),
徳島大学大学院ヘルスバイオサイエンス研究部分子医化学分野, Tokushima, May 2010.
12. Taigo Horiguchi, Keiko Miyoshi, Taro Muto and Takafumi Noma :
生化学実習書 (第4版10刷),
徳島大学大学院ヘルスバイオサイエンス研究部分子医化学分野, Tokushima, May 2009.
13. Taigo Horiguchi, Keiko Miyoshi, Taro Muto and Takafumi Noma :
生化学実習書 (第3版10刷),
徳島大学大学院ヘルスバイオサイエンス研究部分子医化学分野, Tokushima, May 2008.
14. Taigo Horiguchi, Keiko Miyoshi, Taro Muto and Takafumi Noma :
生化学実習書 (第3版9刷),
徳島大学大学院ヘルスバイオサイエンス研究部分子医化学分野, Tokushima, May 2007.
15. Taigo Horiguchi, Keiko Miyoshi, Taro Muto and Takafumi Noma :
生化学実習書 (第3版8刷),
徳島大学大学院ヘルスバイオサイエンス研究部分子医化学分野, Tokushima, May 2006.
16. Taigo Horiguchi, Keiko Miyoshi, Taro Muto and Takafumi Noma :
生化学実習書 (第3版7刷),
徳島大学大学院ヘルスバイオサイエンス研究部分子医化学分野, Tokushima, May 2005.
17. Taigo Horiguchi, Akemichi Ueno, Keiko Miyoshi and Takafumi Noma :
生化学実習書 (第3版6刷),
徳島大学大学院ヘルスバイオサイエンス研究部分子医化学分野, Tokushima, May 2004.
18. Taigo Horiguchi, Akemichi Ueno, Keiko Miyoshi and Takafumi Noma :
生化学実習書 (第3版5刷),
徳島大学歯学部口腔生化学講座, Tokushima, May 2003.
19. Taigo Horiguchi, Akemichi Ueno and Keiko Miyoshi :
生化学実習書 (第3版4刷),
徳島大学歯学部口腔生化学講座, Tokushima, May 2002.

Academic Paper (Judged Full Paper):

1. Shengjian Jin, Takaaki Tsunematsu, Taigo Horiguchi, Yasuhiro Mouri, Wenhua Shao, Keiko Miyoshi, Hiroko Hagita, Motoharu Sarubo, Natsumi Fujiwara, Qi Guangying, Naozumi Ishimaru and Yasusei Kudo :
Involvement of the OTUB1-YAP1 axis in driving malignant behaviors of head and neck squamous cell carcinoma.,
Cancer Medicine, Vol.12, No.24, 22156-22169, 2023.
(Tokushima University Institutional Repository: 118778,   DOI: 10.1002/cam4.6735,   PubMed: 37986681,   CiNii: 1940583859514191616,   Elsevier: Scopus)
2. Shengjian Jin, Taigo Horiguchi, Xiaolong Ma, Shichao Yuan and Qingguo Liu :
Metallic foreign bodies ingestion by schizophrenic patient: a case report,
Annals of Medicine and Surgery, Vol.85, No.4, 1270-1272, 2023.
(DOI: 10.1097/MS9.0000000000000497,   PubMed: 37113887)
3. Jin Shengjian, Yasusei Kudo and Taigo Horiguchi :
The Role of Deubiquitinating Enzyme in Head and Neck Squamous Cell Carcinoma,
International Journal of Molecular Sciences, Vol.24, 552, 2022.
(Tokushima University Institutional Repository: 117925,   DOI: 10.3390/ijms24010552,   PubMed: 36613989,   Elsevier: Scopus)
4. Taigo Horiguchi, Ayako Tanimura, Keiko Miyoshi, Hiroko Hagita, Hisanori Minami and Takafumi Noma :
The Effect of Heterozygous Mutation of Adenylate Kinase 2 Gene on Neutrophil Differentiation.,
International Journal of Molecular Sciences, Vol.23, 16089, 2022.
(Tokushima University Institutional Repository: 117929,   DOI: 10.3390/ijms232416089,   PubMed: 36555730)
5. Taigo Horiguchi, Yumiko Miyake, Keiko Miyoshi, Ayako Tanimura, Hiroko Hagita, Hiroshi Sakaue and Takafumi Noma :
Gene-expression profile reveals the genetic and acquired phenotypes of hyperactive mutant SPORTS rad,
The Journal of Medical Investigation : JMI, Vol.VOL67, No.NO1,2, 51-61, 2020.
(Tokushima University Institutional Repository: 114556,   DOI: 10.2152/jmi.67.51,   PubMed: 32378618)
6. Ayako Tanimura, Keiko Miyoshi, Taigo Horiguchi, Hiroko Hagita, Koichi Fujisawa and Takafumi Noma :
Mitochondrial Activity and Unfolded Protein Response are Required for Neutrophil Differentiation.,
Cellular Physiology and Biochemistry, Vol.47, No.5, 1936-1950, 2018.
(Tokushima University Institutional Repository: 112955,   DOI: 10.1159/000491464,   PubMed: 29972819)
7. Yosi Dian Arinawati, Keiko Miyoshi, Ayako Tanimura, Taigo Horiguchi, Hiroko Hagita and Takafumi Noma :
Deciphering defective amelogenesis using invitro culture systems.,
Journal of Bioscience and Bioengineering, Vol.125, No.Issue 4, 365-496, 2018.
(Tokushima University Institutional Repository: 112952,   DOI: 10.1016/j.jbiosc.2017.11.009,   PubMed: 29397320)
8. A Adiningrat, Ayako Tanimura, Keiko Miyoshi, Hiroko Hagita, RD Yanuaryska, Arinawati Yosi Dian, Taigo Horiguchi and Takafumi Noma :
Isolation and characterization of dental epithelial cells derived from amelogenesis imperfecta rat.,
Oral Diseases, Vol.22, No.2, 132-139, 2016.
(DOI: 10.1111/odi.12396,   PubMed: 26582753,   Elsevier: Scopus)
9. Keiko Miyoshi, Taigo Horiguchi, Ayako Tanimura, Hiroko Hagita and Takafumi Noma :
Gene Signature of Human Oral Mucosa Fibroblasts: Comparison with Dermal Fibroblasts and Induced Pluripotent Stem Cells.,
BioMed Research International, Vol.2015, 121575, 2015.
(Tokushima University Institutional Repository: 114177,   DOI: 10.1155/2015/121575,   PubMed: 26339586,   Elsevier: Scopus)
10. Ryna Dwi Yanuaryska, Keiko Miyoshi, Arya Adiningrat, Taigo Horiguchi, Ayako Tanimura, Hiroko Hagita and Takafumi Noma :
Sp6 regulation of Rock1 promoter activity in dental epithelial cells,
The Journal of Medical Investigation : JMI, Vol.VOL61, No.(NO 3,4), 306-317, 2014.
(Tokushima University Institutional Repository: 109578,   DOI: 10.2152/jmi.61.306,   PubMed: 25264049,   Elsevier: Scopus)
11. Ayako Tanimura, Taigo Horiguchi, Keiko Miyoshi, Hiroko Hagita and Takafumi Noma :
Differential expression of adenine nucleotide converting enzymes in mitochondrial intermembrane space: a potential role of adenylate kinase isozyme 2 in neutrophil differentiation.,
PLoS ONE, Vol.9, No.2, e89916, 2014.
(Tokushima University Institutional Repository: 114179,   DOI: 10.1371/journal.pone.0089916,   PubMed: 24587121,   Elsevier: Scopus)
12. Arya Adiningrat, Ayako Tanimura, Keiko Miyoshi, Ryna Yanuaryska Dwi, Hiroko Hagita, Taigo Horiguchi and Takafumi Noma :
Ctip2-mediated Sp6 transcriptional regulation in dental epithelium-derived cells.,
The Journal of Medical Investigation : JMI, Vol.61, No.1.2, 126-136, 2014.
(Tokushima University Institutional Repository: 109529,   DOI: 10.2152/jmi.61.126,   PubMed: 24705758,   CiNii: 1390001204245161216,   Elsevier: Scopus)
13. Taigo Horiguchi, Miyuki Fuka, Koichi Fujisawa, Ayako Tanimura, Keiko Miyoshi, Ryutaro Murakami and Takafumi Noma :
Adenylate kinase 2 deficiency limits survival and regulates various genes during larval stages of Drosophila melanogaster.,
The Journal of Medical Investigation : JMI, Vol.61, No.1.2, 137-150, 2014.
(Tokushima University Institutional Repository: 109541,   DOI: 10.2152/jmi.61.137,   PubMed: 24705759,   CiNii: 1390282679221871744,   Elsevier: Scopus)
14. Taro Muto, Keiko Miyoshi, Taigo Horiguchi, Hiroko Hagita and Takafumi Noma :
Novel genetic linkage of rat Sp6 mutation to Amelogenesis imperfecta,
Orphanet Journal of Rare Diseases, Vol.7, No.1, 2012.
(Tokushima University Institutional Repository: 114180,   DOI: 10.1186/1750-1172-7-34,   PubMed: 22676574)
15. Taro Muto, Keiko Miyoshi, Taigo Horiguchi and Takafumi Noma :
Dissection of morphological and metabolic differentiation of amelobrasts via ectopic SP6 expression,
The Journal of Medical Investigation : JMI, Vol.59, No.1-2, 59-68, 2012.
(Tokushima University Institutional Repository: 85239,   DOI: 10.2152/jmi.59.59,   PubMed: 22449994)
16. W Trianna Utami, Keiko Miyoshi, Hiroko Hagita, Dwi Ryna Yanuaryska, Taigo Horiguchi and Takafumi Noma :
Possible Linkage of SP6 Transcriptional Activity with Amelogenesis by Protein Stabilization.,
Journal of Biomedicine & Biotechnology, Vol.2011, 2011.
(Tokushima University Institutional Repository: 114183,   DOI: 10.1155/2011/320987,   PubMed: 22046099)
17. Trianna W Utami, Keiko Miyoshi, Hiroko Hagita, Ryna D. Yanuaryska, Taigo Horiguchi and Takafumi Noma :
Dynamic changes of Sp6 Transgene Expression in Dental Epithelial Cells during Long-term Culture,
The Indonesian Journal of Dental Research, Vol.1, No.3, 2011.
(Tokushima University Institutional Repository: 114181,   DOI: 10.22146/theindjdentres.10009)
18. Ivan Arie Wahyudi, Taigo Horiguchi, Keiko Miyoshi, Taro Muto, Trianna Wahyu Utami, Hiroko Hagita and Takafumi Noma :
Isolation and Characterization of Mouse Specificity Protein 6 Promoter,
The Indonesian Journal of Dental Research, Vol.2010, Volume 1, No.1, 21-34, 2010.
(Tokushima University Institutional Repository: 114182,   DOI: 10.22146/theindjdentres.9984)
19. Keiko Miyoshi, Yuki Akazawa, Taigo Horiguchi and Takafumi Noma :
Localization of adenylate kinase 4 in mouse tissues.,
Acta Histochemica et Cytochemica, Vol.42, No.2, 55-64, 2009.
(Tokushima University Institutional Repository: 114185,   DOI: 10.1267/ahc.08012,   PubMed: 19492028,   Elsevier: Scopus)
20. Koichi Fujisawa, Ryutaro Murakami, Taigo Horiguchi and Takafumi Noma :
Adenylate kinase isozyme 2 is essential for growth and development of Drosophila melanogaster.,
Comparative Biochemistry and Physiology. Part B, Biochemistry & Molecular Biology, Vol.153, No.1, 29-38, 2009.
(DOI: 10.1016/j.cbpb.2009.01.006,   PubMed: 19416704,   Elsevier: Scopus)
21. Keiko Miyoshi, Hideya Nagata, Taigo Horiguchi, Kaori Abe, Ivan Wahyudi Arie, Yoshinobu Baba, Hidemitsu Harada and Takafumi Noma :
BMP2-induced gene profiling in dental epithelial cell line.,
The Journal of Medical Investigation : JMI, Vol.55, No.3-4, 216-226, 2008.
(Tokushima University Institutional Repository: 110862,   DOI: 10.2152/jmi.55.216,   PubMed: 18797134)
22. Intan Ruspita, Keiko Miyoshi, Taro Muto, Kaori Abe, Taigo Horiguchi and Takafumi Noma :
Sp6 downregulation of follistatin gene expression in ameloblasts.,
The Journal of Medical Investigation : JMI, Vol.55, No.1-2, 87-98, 2008.
(Tokushima University Institutional Repository: 110844,   DOI: 10.2152/jmi.55.87,   PubMed: 18319550)
23. Kaori Abe, Keiko Miyoshi, Taro Muto, Ruspita Intan, Taigo Horiguchi, Toshihiko Nagata and Takafumi Noma :
Establishment and characterization of rat dental epithelial derived ameloblast-lineage clones.,
Journal of Bioscience and Bioengineering, Vol.103, No.5, 479-485, 2007.
(DOI: 10.1263/jbb.103.479,   PubMed: 17609165,   Elsevier: Scopus)
24. Akemichi Ueno, Yoshihiro Miwa, Keiko Miyoshi, Taigo Horiguchi, Hideo Inoue, Intan Ruspita, Kaori Abe, Kikuji Yamashita, Eiji Hayashi and Takafumi Noma :
Constitutive expression of thrombospondin 1 in MC3T3-E1 osteoblastic cells inhibits mineralization,
Journal of Cellular Physiology, Vol.209, No.2, 322-332, 2006.
(DOI: 10.1002/jcp.20735,   PubMed: 16883596)
25. Akemichi Ueno, Kikuji Yamashita, Keiko Miyoshi, Taigo Horiguchi, Intan Ruspita, Kaori Abe and Takafumi Noma :
Soluble matrix from osteoblastic cells induces mineralization by dental pulp cells,
The Journal of Medical Investigation : JMI, Vol.53, No.3-4, 297-302, 2006.
(Tokushima University Institutional Repository: 110826,   DOI: 10.2152/jmi.53.297,   PubMed: 16953068,   Elsevier: Scopus)
26. Nishikawa Hiroyuki, Akemichi Ueno, Taigo Horiguchi, Kikuji Yamashita, Inoue Hideo and Toshihiko Nagata :
Effects of TGF-beta1 on Extracellular Matrix Formation in Rat Clonal Dental Pulp Cells,
Dentistry in Japan, Vol.38, 44-50, 2002.
27. Xiong Yu, Taigo Horiguchi, Katsuya Shigesada and Edward Egelman :
Three-dimensional Reconstruction of Transcription Termination Factor rho: Orientation of the N-terminal Domain and Visualization of an RNA-binding Site,
Journal of Molecular Biology, Vol.299, No.5, 1279-1287, 2000.
(DOI: 10.1006/jmbi.2000.3810,   PubMed: 10873452,   Elsevier: Scopus)
28. Taigo Horiguchi, Yoshihiro Miwa and Katsuya Shigesada :
The Quaternary Geometry of Transcription Termination Factor rho: Assignment by Chemical Cross-linking,
Journal of Molecular Biology, Vol.269, No.4, 514-528, 1997.
29. Yoshihiro Miwa, Taigo Horiguchi and Katsuya Shigesada :
Structural and Functional Dissections of Transcription Termination Factor Rho by Random Mutagenesis,
Journal of Molecular Biology, Vol.254, No.5, 815-837, 1995.

Academic Paper (Unrefereed Paper):

1. Taigo Horiguchi :
Microarray Data Analysis Mainly on a Functional Analysis using DAVID,
Journal of Oral Health and Biosciences, Vol.29, No.2, 55-62, 2017.
(Tokushima University Institutional Repository: 111060,   DOI: 10.20738/johb.29.2_55,   CiNii: 1390282680799299840)

Proceeding of International Conference:

1. Keiko Miyoshi, Arinawati Yosi Dian, Hagita Hiroko, Taigo Horiguchi and Takafumi Noma :
Possible roles of Sp6 in ameloblast differentiation,
The 6th International Conference on Biology and Pathobiology of KLF/Sp Transcription Factors, Oct. 2018.
2. Ayako Tanimura, Keiko Miyoshi, Taigo Horiguchi, Hagita Hiroko, Koichi Fujisawa and Takafumi Noma :
A role of ER stress and UPR on hematopoietic differentiation,
51st Miami Winter Symposium, Stem Cells Todays Research Tomorrows Therapies, Miami, Jan. 2018.
3. Arinawati Yosi Dian, Keiko Miyoshi, Ayako Tanimura, Taigo Horiguchi and Takafumi Noma :
Comparative study of gene profiling using 2D and 3D culture as an in vitro amelogenesis imperfecta model,
Internationl Joint meeting 4th ASEAN plus Tokushima Joint International Conference, Dec. 2017.
4. Ayako Tanimura, Keiko Miyoshi, Taigo Horiguchi, Hagita Hiroko, Koichi Fujisawa and Takafumi Noma :
Impact of mitochondrial ATP production on neutrophil differentiation,
Gordon Research Conference(From Molecular Structures and Mechanisms to Cellular Bioenergetics in Health and Disease), Jun. 2017.
5. Keiko Miyoshi, Hagita Hiroko, Arinawati Yosi Dian, Ayako Tanimura, Taigo Horiguchi and Takafumi Noma :
Regulation of SP6 protein expression in stably transformed dental epithelial cells,
12th International Conference on Tooth Morphogenesis and Differentiation, Porvoo,Finland, Jun. 2016.
6. Keiko Miyoshi, Adiningrat Arya, Ayako Tanimura, Yanuaryska Dwi Ryna, Arinawati Yosi Dian, Taigo Horiguchi and Takafumi Noma :
Establishment of an in Vitro amelogenesis imperfecta model,
Challenge to Intractable Oral Diseases International Symposium 2015 which takes place at Yumikura Hall,Osaka University Graduate School of Dentistry in Japan from 10-11 December 2015, Dec. 2015.
7. Taigo Horiguchi, Keiko Miyoshi, Ayako Tanimura, H. Hagita, Y. Miyatake, Hiroshi Sakaue and Takafumi Noma :
Gene expression analysis of hyperactive mutant SPORTS rat,
Cell Symposia:Exercise and Metabolism which takes place at NH Grand Krasnapolsky Hotel Amsterdam from 12-14 July 2015, Amsterdam, Jul. 2015.
8. Hiroko Hagita, Keiko Miyoshi, Taigo Horiguchi, Ayako Tanimura, Arya Adiningrat, Dian Yosi Arinawati and Takafumi Noma :
Analysis of GBA1 gene structure and expression,
The 11th International workshop on Advanced Genomics, Tokyo, May 2015.
9. Keiko Miyoshi, Taigo Horiguchi, Ayako Tanimura, Hiroko Hagita, Yoshihiro Touda, Shoji Kagami, Kenji Mori, Daisuke Tsuji, Kouji Itou and Takafumi Noma :
Gaucher disease caused by possible atypical mechanism,
Gordon Research Conference, USA,Texas,Galveston(Hotel Galvez), Mar. 2015.
10. Ayako Tanimura, Taigo Horiguchi, Keiko Miyoshi, Hiroko Hagita and Takafumi Noma :
Adenylate Kinase 2 Regulates Neutrophil Differentiation Via Mitochondrial,
The 3rd ASEAN Plus and Tokushima Joint International Conference, Makassar,Indonesia, Dec. 2014.
11. Arya Adinigrat, Ayako Tanimura, Keiko Miyoshi, Ryna Dwi Yanuaryska, Hiroko Hagita, Taigo Horiguchi and Takafumi Noma :
Ctip2 Regulation Of Tooth Development Via Sp6 Gene Expression,
The 3rd ASEAN Plus and Tokushima Joint International Conference, Makassar,Indonesia, Dec. 2014.
12. Ayako Tanimura, Taigo Horiguchi, Keiko Miyoshi, Hiroko Hagita and Takafumi Noma :
A role of adenine nucleotide converting enzymes in the mitochondrial intermembrane space on the hematopoietic cell differentiation,
Keystone meeting Mitochondrial Dynamics and Physiology, SantaFe, New Mexico, USA, Feb. 2014.
13. Taigo Horiguchi, Miyuki Fuka, Koichi Fujisawa, Ayako Tanimura, Keiko Miyoshi, Ryutaro Murakami and Takafumi Noma :
A Role of AK2 during Development of Drosohila melanogaster,
The 4th International Symposium on Dynamics of Mitochondria, Oct. 2013.
14. Arya Adiningrat, Keiko Miyoshi, Hiroko Hagita, Taigo Horiguchi, Ayako Tanimura, Ryna Dwi Yanuaryska and Takafumi Noma :
Role of Bcl11b/Ctip2 on Sp6 Gene Expression in Dental Epithelial Cell,
ASEAN PLUS and TOKUSHIMA JOINT INTERNATIONAL CONFERENCE, Dec. 2012.
15. Ryna Dwi Yanuaryska, Keiko Miyoshi, Taigo Horiguchi, Ayako Tanimura, Hiroko Hagita, Arya Adiningrat and Takafumi Noma :
SP6 Regulation of Rock1 Expression in Dental Epithelial Cells,
ASEAN PLUS and TOKUSHIMA JOINT INTERNATIONAL CONFERENCE, Tokushima, Dec. 2012.
16. Keiko Miyoshi, Taro Muto, Taigo Horiguchi, Hiroko Hagita and Takafumi Noma :
A frameshift mutation in Sp6 linked to Amelogenesis imperfecta,
ASEAN PLUS and TOKUSHIMA JOINT INTERNATIONAL CONFERENCE, Tokushima, Dec. 2012.
17. Trianna W Utami, Keiko Miyoshi, Hiroko Hagita, Ryna D Yanuaryska, Taigo Horiguchi and Takafumi Noma :
REGULATION OF SP6 GENE EXPRESSION AND CELL TYPE SPECIFIC FUNCTION OF SP6 IN DENTAL EPITHELIAL CELLS,
The 2nd International Joint Sypmosium on Oral and Dental Sciences In Conjuction with Dental Specialists Seminar, Mar. 2012.
18. Utami Wahyu Trianna, Keiko Miyoshi, Taigo Horiguchi, Taro Muto, Wahyudi Arie Ivan, Hiroko Hagita and Takafumi Noma :
Differential regulation of Sp6 silencing in dental epithelial cells,
Inter national Joint Symposium on Oral Science, Dec. 2010.
19. Ivan Arie Wahyudi, Taigo Horiguchi, Keiko Miyoshi, Taro Muto, Trianna Wahyu Utami, Hagita Hiroko and Takafumi Noma :
Caracterization of Specificity Protein 6 promoter Activity,
International Joint Symposium on Oral Science, Dec. 2010.
20. Takafumi Noma, Taro Muto, Keiko Miyoshi, Taigo Horiguchi, Hiroko Hagita, Wahyudi Arie Ivan and Utami Wahyu Trianna :
From a study of tooth morphology and development to a perspective for the future regeneration therapy,
ガジャマダ大学 創立62年 記念講演会, Feb. 2010.
21. Ruspita Intan, Keiko Miyoshi, Taro Muto, Kaori Abe, Taigo Horiguchi and Takafumi Noma :
Identification of Sp6 target gene in dental epithelial cells,
Gordon Research Conferences, Feb. 2008.
22. Keiko Miyoshi, Taigo Horiguchi, Kazuki Abe, Inoue Hideo and Takafumi Noma :
Effects of glycyrrhizin on the gene expression in CC14-induced hepatitis,
8th World Congress on Inflammation, Jun. 2007.
23. Takafumi Noma, Keiko Miyoshi, Yuki Akazawa and Taigo Horiguchi :
Tissue-ditribution and possible functional roles of AK4,
Mitchondrial Medicine 2007: Riding the Wave of the Future, Jun. 2007.
24. Takafumi Noma, Keiko Miyoshi, Yuki Akazawa and Taigo Horiguchi :
Tissue-distribution and possible functional roles of AK4,
Mitochondrial Medicine Meeting, San Diego, Jun. 2007.
(DOI: 10.1016/j.mito.2007.08.016)
25. Kaori Abe, Keiko Miyoshi, Taro Muto, Intan Ruspita, Taigo Horiguchi, Toshihiko Nagata and Takafumi Noma :
Establishment and charactarization of rat ameloblast-lineage clones,
The 19th Annual and International Meeting of the Japanese Association for Animal Cell Technology, Kyoto, Sep. 2006.
26. Keiko Miyoshi, Taigo Horiguchi, Kaori Abe, Akemichi Ueno, Hideya Nagata, Yoshinobu Baba, Hidemitsu Harada and Takafumi Noma :
Effects of BMP2 on Gene Expression in Dental Epithelial Cell Line,
Eight International Conference on Tooth Morphogenesis and Differentiation, York, UK, Jul. 2004.

Proceeding of Domestic Conference:

1. Jin Shengjian, Takaaki Tsunematsu, Taigo Horiguchi, Yasuhiro Mouri, Wenhua Shao, Keiko Miyoshi, Noriko Mizusawa, Hagita Hiroko, Sarubo Motoharu, Yoshida Kayo, Kaya Yoshida, Natsumi Fujiwara, Kazumi Ozaki, Naozumi Ishimaru and Yasusei Kudo :
The role of deubiquitinating enzyme, OTUB1 in head and neck squamous cell carcinoma (HNSCC) progression,
第82回日本癌学会学術集会, Sep. 2023.
2. Jin Shengjian, Takaaki Tsunematsu, Taigo Horiguchi, Yasuhiro Mouri, Wenhua Shao, Keiko Miyoshi, Noriko Mizusawa, Hiroko Hagita, YOSHIDA Kayo, Kaya Yoshida, Natsumi Fujiwara, Kazumi Ozaki, Naozumi Ishimaru and Yasusei Kudo :
The role of Deubiquitinating enzyme, OTUB1 in head and neck squamous cell carcinoma (HNSCC) progression,
第61回四国歯学会, Mar. 2023.
3. Keiko Miyoshi, Taigo Horiguchi and Ayako Tanimura :
GBA遺伝子構造の再定義と細胞特異的発現制御機構の解析,
第64回歯科基礎医学会学術大会, Sep. 2022.
4. shengjian jin, Takaaki Tsunematsu, Taigo Horiguchi, Naozumi Ishimaru and Yasusei Kudo :
脱ユビキチン化酵素OTUB1の頭頸部扁平上皮癌の進展における役割,
第64回歯科基礎医学会学術大会, Sep. 2022.
5. Taigo Horiguchi, Keiko Miyoshi, 萩田 浩子 and Takafumi Noma :
運動が遺伝子発現に与える影響の網羅的解析,
四国歯学会56回例会, Feb. 2020.
6. Keiko Miyoshi, Taigo Horiguchi, 萩田 浩子 and Takafumi Noma :
再生歯学戦略におけるヒト口腔粘膜由来線維芽細胞の特性,
四国歯学会56回例会, Feb. 2020.
7. Arinawati Yosi Dian, Keiko Miyoshi, Hagita Hiroko, Taigo Horiguchi and Takafumi Noma :
Perturbation of gene regulateion in an in vitro amelogenesis imperfecta model,
The 91st Annual Meeting of the Japanese Biochemical Society, Sep. 2018.
8. Arinawati Yosi Dian, Keiko Miyoshi, Taigo Horiguchi and Takafumi Noma :
アメロジェネシスのステージ特異的な遺伝子制御におけるSp6の関与,
第60回歯科基礎医学会学術大会, Sep. 2018.
9. Arinawati Yosi Dian, Keiko Miyoshi, Hagita Hiroko, Taigo Horiguchi and Takafumi Noma :
Demonstration of defective amelogenesis using an in vitro amelogenesis imperfecta model,
第257回徳島医学会学術集会, Aug. 2018.
10. Keiko Miyoshi, hagita hiroko, Ayako Tanimura, Taigo Horiguchi and Takafumi Noma :
5´end structure of GBA and expression profile of its variants,
2017年度生命科学系学会合同年次大会 ConBio 2017, Dec. 2017.
11. Ayako Tanimura, Keiko Miyoshi, Taigo Horiguchi, hagita hiroko, Koichi Fujisawa and Takafumi Noma :
ミトコンドリアがUPR活性をコントロールして免疫細胞分化の方向を決定づける,
第17回日本ミトコンドリア学会年会, Nov. 2017.
12. Yosi Dian Arinawati, Keiko Miyoshi, Ayako Tanimura, Taigo Horiguchi and Takafumi Noma :
エナメル質形成不全モデルにおけるアメロジェネシス関連遺伝子発現プロファイル,
第59回歯科基礎医学会学術大会, Sep. 2017.
13. Ayako Tanimura, Keiko Miyoshi, Taigo Horiguchi, Koichi Fujisawa and Takafumi Noma :
CRISPR/Cas9を用いたAK2の段階的欠損による細胞代謝への影響,
The 2nd ANNUAL MEETING OF THE JAPANESE SOCIETY FOR GENOME EDITING, Jun. 2017.
14. Ayako Tanimura, Taigo Horiguchi, Keiko Miyoshi, Arinawati Yosi Dian and Takafumi Noma :
HL-60細胞を用いた血球分化時におけるUnfolded protein responseの解析,
第57回 日本生化学会 中国・四国支部例会, May 2016.
15. Taigo Horiguchi :
マイクロアレイデータ解析法 ─DAVIDによる機能解析を中心に─,
四国歯学会第48回例会, Mar. 2016.
16. Taigo Horiguchi, Keiko Miyoshi, Ayako Tanimura, Hagita Hiroko, Miyatake Yumiko, Hiroshi Sakaue and Takafumi Noma :
運動能が亢進したSPORTSラットの遺伝子発現解析,
第38回 日本分子生物学会,第88回 日本生化学会 合同大会, Dec. 2015.
17. Keiko Miyoshi, Taigo Horiguchi, Ayako Tanimura, Hiroko Hagita and Takafumi Noma :
ヒト口腔粘膜線維芽細胞の特性:皮膚線維芽細胞,iPS細胞との網羅的遺伝子発現の比較解析,
The 14th Congress of the Japanese Society for Regenerative Medicine, Mar. 2015.
18. 青山 修平, 深 美由紀, Taigo Horiguchi, Takafumi Noma, 原田 由美子 and 村上 柳太郎 :
ショウジョウバエアデニル酸キナーゼ2 (AK2) の発生時期特異的ノックダウン,
第37回日本分子生物学会年会, Nov. 2014.
19. Arya Adiningrat, Keiko Miyoshi, Ryna Dwi Yanuaryska, Hiroko Hagita, Taigo Horiguchi, Ayako Tanimura and Takafumi Noma :
Establishment and Characterization of Dental Epithelial Cells Derived from Amelogenesis Imperfecta Rat,
第87回日本生化学会大会, Oct. 2014.
20. Arya Adiningrat, Ayako Tanimura, Keiko Miyoshi, Ryna Dwi Yanuaryska, Hiroko Hagita, Taigo Horiguchi and Takafumi Noma :
Ctip2 role in Sp6 transcriptional regulation in dental epithelial-derived cells,
2014 Tokushima Bioscience Retreat, Sep. 2014.
21. 青山 修平, 深美 由紀, Taigo Horiguchi, Takafumi Noma, 原田 由美子 and 村上 柳太郎 :
アデニル酸キナーゼ2の時期特異的ノックダウン,
(), May 2014.
22. Taigo Horiguchi :
2013 「ストレスと栄養クラスター」研究報告会,
「アデニル酸キナーゼ2 ノックアウトフライを用いたヒト重症免疫不全症の基礎研究」, Dec. 2013.
23. Adiningrat Arya, Ayako Tanimura, Keiko Miyoshi, Yanuaryska Dwi Ryna, Taigo Horiguchi, 萩田 浩子 and Takafumi Noma :
Role of Ctip2 in Sp6 gene regulation,
第36回日本分子生物学会年会, Dec. 2013.
24. 青山 修平, 深 美由紀, Taigo Horiguchi, Takafumi Noma, 原田 由美子 and 村上 柳太郎 :
ショウジョウバエアデニル酸キナーゼ(AK2)の発生時期特異的ノックダウン,
第36回日本分子生物学会年会, Dec. 2013.
25. Yanuaryska Dwi Ryna, Keiko Miyoshi, Taigo Horiguchi, Ayako Tanimura, Adiningrat Arya and Takafumi Noma :
SP6 Positiyvely Regulates Rock1 Promoter Activity in Dental Epithelial Cells,
第55回歯科基礎医学会, Sep. 2013.
26. 大本 卓司, 吉谷 信幸, Taigo Horiguchi and Naomi Sakashita :
皮膚腫瘍,
第111回中国四国スライドカンファレンス, Jun. 2013.
27. Keiko Miyoshi, Yanuaryska Dwi Ryna, Adiningrat Arya, 萩田 浩子, Ayako Tanimura, Taigo Horiguchi and Takafumi Noma :
転写因子SP6の構造と機能解析,
第54回 日本生化学会 中国・四国支部例会, Jun. 2013.
28. Ryna Dwi Yanuaryska, Keiko Miyoshi, Taigo Horiguchi, Ayako Tanimura, Hiroko Hagita and Takafumi Noma :
SP6 and AP2 regulate Rock1 expression in dental epithelial cells,
第54回 日本生化学会 中国・四国支部例会, May 2013.
29. Ayako Tanimura, Taigo Horiguchi, Hiroko Hagita, Keiko Miyoshi and Takafumi Noma :
アデニル酸キナーゼ2の血球系分化への影響,
第54回 日本生化学会 中国・四国支部例会, May 2013.
30. Taigo Horiguchi, Ayako Tanimura, HIROKO HAGITA, Keiko Miyoshi and Takafumi Noma :
SPRTSラットにおける遺伝子発現パターンとその意義,
第54回 日本生化学会 中国・四国支部例会, May 2013.
31. 佐藤 綾, Naomi Sakashita, Taigo Horiguchi and Seiko Kagawa :
総肺静脈灌流異常修復術後性肺静脈狭窄病変におけるHic-5陽性平滑筋細胞の意義,
第102回日本病理学会, May 2013.
32. Taigo Horiguchi, Ayako Tanimura, Keiko Miyoshi and Takafumi Noma :
SPORTSラットにおけるAK isozymesの発現パターンとその意義,
平成24年度「ストレスと栄養クラスター」の研究報告会, Jan. 2013.
33. Ayako Tanimura, Taigo Horiguchi, Keiko Miyoshi and Takafumi Noma :
ミトコンドリア膜間酵素AK2の細胞分化における役割,
平成24年度「ストレスと栄養クラスター」の研究報告会, Jan. 2013.
34. 深 美由紀, 阿武 雅之, Taigo Horiguchi, Koichi Fujisawa, Takafumi Noma and 村上 柳太郎 :
Functional Analysis of the Drosophila Adenylate Kinase Genes AK1,AK2 and AK3,
第35回 日本分子生物学会, Dec. 2012.
35. Keiko Miyoshi, Taro Muto, Taigo Horiguchi, 萩田 浩子 and Takafumi Noma :
エナメル質形成不全症の新規変異遺伝子の発見,
日本人類遺伝学会 第57回大会, Oct. 2012.
36. Taigo Horiguchi :
Investigation into Pathogenic Mechanism of Reticular Dysgenesis Using iPS Cells Derived frome Human Oral Fibroblast,
平成23年度再生工学カテゴリー研究報告会, Feb. 2012.
37. 深 美由紀, 阿武 雅之, Taigo Horiguchi, Koichi Fujisawa, Takafumi Noma and 村上 柳太郎 :
Functionla analysis of Drosophila adenylate kinase-2(Dak2),
第34回日本分子生物学会, Dec. 2011.
38. Yanuaryska Dwi Ryna, Keiko Miyoshi, Utami Wahyu Trianna, Taigo Horiguchi and Takafumi Noma :
Identification of SP6 Target Genes inRat Dental Epithelial Cell,
第53回 歯科基礎医学会学術大会・総会, Oct. 2011.
39. Utami Wahyu Trianna, Keiko Miyoshi, Hiroko Hagita, Yanuaryska Dwi Ryna, Taigo Horiguchi and Takafumi Noma :
SP6 Stability and Functional Linkage during Amelogenesis,
第84回 日本生化学会大会, Sep. 2011.
40. Takafumi Noma, Taro Muto, Keiko Miyoshi and Taigo Horiguchi :
Sp6トランスジェニックラットに見られた鉄代謝異常,
第35回日本鉄バイオサイエンス学会, Sep. 2011.
41. Utami Wahyu Triannna, Keiko Miyoshi, Taigo Horiguchi, Wahyudi A Ivan, Hiroko Hagita, Yanuaryska D Ryna and Takafumi Noma :
Regulation of Sp6 expression and function in C9 cells,
第52回 日本生化学会中国 四国支部例会, May 2011.
42. Utami Wahyu Trianna, Keiko Miyoshi, Taigo Horiguchi, Taro Muto, Wahyudi Arie Ivan, Hiroko Hagita and Takafumi Noma :
Regulation of Sp6 expression in CHA9 cells,
第33回 日本分子生物学会 第83回日本生化学会, Dec. 2010.
43. Wahyudi Arie Ivan, Taigo Horiguchi, Keiko Miyoshi, Taro Muto, Utami Wahyu Trianna, Hiroko Hagita and Takafumi Noma :
Isolation and Characterization of Mouse Specificity Protein 6 Promoter,
第33回 日本分子生物学会 第83回 日本生化学会, Dec. 2010.
44. Utami Wahyu Trianna, Keiko Miyoshi, Taigo Horiguchi, Taro Muto, Hiroko Hagita and Takafumi Noma :
Regulation of Sp6 expression in CHA9 cells,
2010 Tokushima Bioscience Retreat, Sep. 2010.
45. Wahyudi Arie Ivan, Taigo Horiguchi, Keiko Miyoshi, Taro Muto, Hiroko Hagita and Takafumi Noma :
Isolation and Characterization of Mouse Specificity Protein 6 Promoter,
2010 Tokushima Bioscience Retreat, Sep. 2010.
46. Wahyudi Arie IVAN, Taigo Horiguchi, Keiko Miyoshi, Taro Muto and Takafumi Noma :
Regulation of Sp6 Expression in Dental Epthelial Cells,
ミニリトリート若手研究報告会 「ストレスと栄養クラスター」, Feb. 2010.
47. Wahyudi Arie Ivan, Taigo Horiguchi, Keiko Miyoshi, Taro Muto and Takafumi Noma :
Regulation of Sp6 expression in dental epithelial cells,
第51回 歯科基礎医学会, Sep. 2009.
48. Ruspita Ita, Keiko Miyoshi, Taro Muto, Taigo Horiguchi, Kaori Abe, Takafumi Noma and Toshihiko Nagata :
A possible role of Sp6 in Amelogenesis,
「魅力ある大学院教育」イニシアティブ 「21世紀の口腔科学が目指すべき方向性」, Dec. 2007.
49. Ruspita Intan, Keiko Miyoshi, Taro Muto, Taigo Horiguchi, Kaori Abe and Takafumi Noma :
Sp6 induced down-regulation of follistatin gene in rat dental epithelial cells,
第49回歯科基礎医学学術大会, Aug. 2007.
50. Kaori Abe, Keiko Miyoshi, Taro Muto, Taigo Horiguchi, Ruspita Intan, Toshihiko Nagata and Takafumi Noma :
Redox regulation of amelogenin gene expression,
第49回歯科基礎医学学術大会, Aug. 2007.
51. Kaori Abe, Keiko Miyoshi, Taro Muto, Taigo Horiguchi, Ruspita Ita, Takafumi Noma and Toshihiko Nagata :
MAPK activation via ROS induces amelognin expression in the ameloblast-lineage cells,
「魅力ある大学院教育」イニシアティブ 「21世紀の口腔科学が目指すべき方向性」, 2007.

Grants-in-Aid for Scientific Research (KAKEN Grants Database @ NII.ac.jp)

  • Investigation of novel oral cancer-specific molecular targets based on genetic diversity (Project/Area Number: 23K24546 )
  • RNA修飾による糖脂質分解酵素活性制御機構の解明とゴーシェ病克服への挑戦 (Project/Area Number: 22K09913 )
  • Identification of signal targets in neutrophil differentiation (Project/Area Number: 19K10090 )
  • Study on elucidation of the pathophysiology of rare intractable diseases (reticular dysgenesis) with severe combined immunodeficiency and development of therapeutic methods (Project/Area Number: 15K11072 )
  • Characterization of Gaucher disease by new gene mutation using patient-derived oral mucosa fibroblasts (Project/Area Number: 15K11041 )
  • Development of sensors for monitoring intracellular ATP and GTP. (Project/Area Number: 16591858 )
  • 象牙質に特異的な非コラーゲン性蛋白質の機能に関する研究 (Project/Area Number: 13771096 )
  • Search by Researcher Number (70304532)