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Tokushima University > Graduate School of Biomedical Sciences > 医学域 > Medical Nutrition > Medical Nutrition > 応用栄養学 >
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Research Activity

Field of Study

Subject of Study

Book / Paper

Book:

1.Ichiro Kaneko and Masashi Kuwahata :
病態栄養ガイドブック(改訂第6版)第2章1栄養素の代謝と生理機能,
Nankodo, May 2019.
2.Ken-ichi Miyamoto and Ichiro Kaneko :
ロス医療栄養科学大事典7章カルシウム,8章リン,
西村書店, Nov. 2018.
3.Sawako Tatsumi, Ichiro Kaneko, Hiroko Segawa and Ken-ichi Miyamoto :
生体におけるリン代謝調節:多臓器連関について,
Oct. 2018.
4.Ken-ichi Miyamoto, 井上 裕康, Masashi Kuwahata and Ichiro Kaneko :
分子栄養学,
Kodansha, Mar. 2018.
5.Ichiro Kaneko :
ミネラル(無機質)の栄養,
Nov. 2016.
6.Ichiro Kaneko, Hiroko Segawa, Sawako Tatsumi and Ken-ichi Miyamoto :
尿細管リン再吸収障害によるくる病/骨軟化症.,
TOKYO IGAKUSHA, Jun. 2016.
7.宮川 淳美, Ichiro Kaneko and Ken-ichi Miyamoto :
栄養療法によるリン管理.,
Iyaku Journal Co., Ltd., Jun. 2016.
8.Ichiro Kaneko, Hiroko Segawa, Sawako Tatsumi and Ken-ichi Miyamoto :
FGF23,
科学評論社, Dec. 2015.
9.Sawako Tatsumi, Ichiro Kaneko, Hiroko Segawa and Ken-ichi Miyamoto :
生体内リン恒常性維持機構―多臓器関連制御,
日本DDS学会, Nov. 2014.

Academic Paper (Judged Full Paper):

1.Toru Fujii, Hiroko Segawa, Ai Hanazaki, Shiori Nishiguchi, Sakura Minoshima, Akiko Ohi, Rieko Tominaga, Sumire Sasaki, Kazuya Tanifuji, Megumi Koike, Yuki Arima, Yuji Shiozaki, Ichiro Kaneko, Mikiko Ito, Sawako Tatsumi and Ken-ichi Miyamoto :
Role of the putative PKC phosphorylation sites of the type IIc sodium-dependent phosphate transporter in parathyroid hormone regulation.,
Clinical and Experimental Nephrology, Vol.23, No.7, 898-907, 2019.
(DOI: 10.1007/s10157-019-01725-6,   PubMed: 30895530)
2.Kayo Ikuta, Hiroko Segawa, Ai Hanazaki, Toru Fujii, Ichiro Kaneko, Yuji Shiozaki, Sawako Tatsumi, Yasuko Ishikawa and Ken-ichi Miyamoto :
Systemic network for dietary inorganic phosphate adaptation among three organs.,
Pflügers Archiv : European Journal of Physiology, Vol.471, No.1, 123-136, 2018.
(DOI: 10.1007/s00424-018-2242-9,   PubMed: 30523405)
3.Toru Fujii, Yuji Shiozaki, Hiroko Segawa, Shiori Nishiguchi, Ai Hanazaki, Miwa Noguchi, Ruri Kirino, Sumire Sasaki, Kazuya Tanifuji, Megumi Koike, Mizuki Yokoyama, Yuki Arima, Ichiro Kaneko, Sawako Tatsumi, Mikiko Ito and Ken-ichi Miyamoto :
Analysis of opossum kidney NaPi-IIc sodium-dependent phosphate transporter to understand Pi handling in human kidney.,
Clinical and Experimental Nephrology, Vol.23, No.3, 313-324, 2018.
(DOI: 10.1007/s10157-018-1653-4,   PubMed: 30317447)
4.Shohei Sasaki, Hiroko Segawa, Ai Hanazaki, Ruri Kirino, Toru Fujii, Kayo Ikuta, Miwa Noguchi, Sumire Sasaki, Megumi Koike, Kazuya Tanifuji, Yuji Shiozaki, Ichiro Kaneko, Sawako Tatsumi, Takaaki Shimohata, Yoshichika Kawai, Sonoko Narisawa, Luis José Millán and Ken-ichi Miyamoto :
A Role of Intestinal Alkaline Phosphatase 3 (Akp3) in Inorganic Phosphate Homeostasis.,
Kidney & Blood Pressure Research, Vol.43, No.5, 1409-1424, 2018.
(Tokushima University Institutional Repository: 113608,   DOI: 10.1159/000493379,   PubMed: 30212831)
5.Jennifer Price Hackney, J Bentley Hanish, E Carl Wagner, Ichiro Kaneko, W Peter Jurutka and A Pamela Marshall :
Dataset on the response of Hut78 cells to novel rexinoids.,
Data in Brief, Vol.20, 1797-1803, 2018.
(DOI: 10.1016/j.dib.2018.09.012,   PubMed: 30294626)
6.MS Sabir, MR Haussler, S Mallick, Ichiro Kaneko, DA Lucas, CA Haussler, GK Whitfield and PW Jurutka :
Optimal vitamin D spurs serotonin: 1,25-dihydroxyvitamin D represses serotonin reuptake transport (SERT) and degradation (MAO-A) gene expression in cultured rat serotonergic neuronal cell lines.,
Genes & Nutrition, 13-19, 2018.
(DOI: 10.1186/s12263-018-0605-7,   PubMed: 30008960)
7.Ichiro Kaneko, Hiroko Segawa, Ikuta Kayo, Hanazaki Ai, Fujii Toru, Sawako Tatsumi, Kido Shinsuke, Hasegawa Tomoka, Amizuka Norio, Saito Hitoshi and Ken-ichi Miyamoto :
Eldecalcitol Causes FGF23 Resistance for Pi Reabsorption and Improves Rachitic Bone Phenotypes in the Male Hyp Mouse.,
Endocrinology, Vol.159, No.7, 2741-2758, 2018.
(DOI: 10.1210/en.2018-00109,   PubMed: 29878089)
8.BJ Hanish, JF Price Hackney, Ichiro Kaneko, N Ma, A der Vaart van, CE Wagner, PW Jurutka and PA Marshall :
A novel gene expression analytics-based approach to structure aided design of rexinoids for development as next-generation cancer therapeutics.,
Steroids, Vol.135, 36-49, 2018.
(DOI: 10.1016/j.steroids.2018.04.009,   PubMed: 29704526,   Elsevier: Scopus)
9.Atsumi Miyagawa, Sawako Tatsumi, Wako Takahama, Osamu Fujii, Kenta Nagamoto, Emi Kinoshita, Kengo Nomura, Kayo Ikuta, Toru Fujii, Ai Hanazaki, Ichiro Kaneko, Hiroko Segawa and Ken-ichi Miyamoto :
The sodium phosphate cotransporter family and nicotinamide phosphoribosyltransferase contribute to the daily oscillation of plasma inorganic phosphate concentration.,
Kidney International, Vol.93, No.5, 1073-1085, 2018.
(DOI: 10.1016/j.kint.2017.11.022,   PubMed: 29398136)
10.CM Dussik, M Hockley, A Grozić, Ichiro Kaneko, L Zhang, MS Sabir, J Park, J Wang, CA Nickerson, SH Yale, CJ Rall, AE Foxx-Orenstein, CM Borror, TR Sandrin and PW Jurutka :
Gene Expression Profiling and Assessment of Vitamin D and Serotonin Pathway Variations in Patients With Irritable Bowel Syndrome.,
Journal of Neurogastroenterology and Motility, Vol.24, No.1, 96-106, 2018.
(DOI: 10.5056/jnm17021,   Elsevier: Scopus)
11.Osamu Fujii, Sawako Tatsumi, Mao Ogata, Tomohiro Arakaki, Haruna Sakaguchi, Kengo Nomura, Atsumi Miyagawa, Kayo Ikuta, Ai Hanazaki, Ichiro Kaneko, Hiroko Segawa and Ken-ichi Miyamoto :
Effect of Osteocyte-Ablation on Inorganic Phosphate Metabolism: Analysis of Bone-Kidney-Gut Axis.,
Frontiers in Endocrinology, Vol.8, 2017.
(Tokushima University Institutional Repository: 112958,   DOI: 10.3389/fendo.2017.00359,   PubMed: 29312149)
12.Kayo Ikuta, Hiroko Segawa, Shohei Sasaki, Ai Hanazaki, Toru Fujii, Aoi Kushi, Yuka Kawabata, Ruri Kirino, Sumire Sasaki, Miwa Noguchi, Ichiro Kaneko, Sawako Tatsumi, Otoya Ueda, Naoko Wada, Hiromi Tateishi, Mami Kakefuda, Yosuke Kawase, Shuichi Ohtomo, Yasuhiro Ichida, Akira Maeda, Kou-Ichi Jishage, Naoshi Horiba and Ken-ichi Miyamoto :
Effect of Npt2b deletion on intestinal and renal inorganic phosphate (Pi) handling.,
Clinical and Experimental Nephrology, Vol.22, No.3, 517-528, 2017.
(Tokushima University Institutional Repository: 111601,   DOI: 10.1007/s10157-017-1497-3,   PubMed: 29128884)
13.Sawako Tatsumi, A Miyagawa, Ichiro Kaneko, Y Shiozaki, Hiroko Segawa and Ken-ichi Miyamoto :
Regulation of renal phosphate handling: inter-organ communication in health and disease.,
Journal of Bone and Mineral Metabolism, Vol.34, No.1, 1-10, 2016.
(DOI: 10.1007/s00774-015-0705-z,   PubMed: 26296817)
14.Ichiro Kaneko, K Rimpi Saini, P Kristin Griffin, Kerr Graham Whitfield, R Mark Haussler and W Peter Jurutka :
FGF23 gene regulation by 1,25-dihydroxyvitamin D: opposing effects in adipocytes and osteocytes.,
The Journal of Endocrinology, 2015.
(DOI: 10.1530/JOE-15-0225,   PubMed: 26148725)
15.Ichiro Kaneko, S Marya Sabir, M Christopher Dussik, Kerr G Whitfield, Amitis Karrys, Jui-Cheng Hsieh, R Mark Haussler, B Mark Meyer, Wesley J Pike and W Peter Jurutka :
1,25-Dihydroxyvitamin D regulates expression of the tryptophan hydroxylase 2 and leptin genes: implication for behavioral influences of vitamin D.,
The FASEB journal, Vol.29, No.9, 4023-4035, 2015.
(DOI: 10.1096/fj.14-269811,   PubMed: 26071405,   Elsevier: Scopus)
16.Yuji Shiozaki, Hiroko Segawa, Saori Ohnishi, Akiko Ohi, Mikiko Ito, Ichiro Kaneko, Shinsuke Kido, Sawako Tatsumi and Ken-ichi Miyamoto :
Relationship between sodium-dependent phosphate transporter (NaPi-IIc) function and cellular vacuole formation in opossum kidney cells.,
The Journal of Medical Investigation : JMI, Vol.62, No.3-4, 209-218, 2015.
(Tokushima University Institutional Repository: 111281,   DOI: 10.2152/jmi.62.209,   PubMed: 26399350,   Elsevier: Scopus)
17.A Pamela Marshall, W Peter Jurutka, E Carl Wagner, Arjan der Vaart van, Ichiro Kaneko, I Pedro Chavez, Ning Ma, S Jaskaran Bhogal, Pritika Shahani, C Johnathon Swierski and Mairi MacNeill :
Analysis of differential secondary effects of novel rexinoids: select rexinoid X receptor ligands demonstrate differentiated side effect profiles.,
Pharmacology Research & Perspectives, Vol.3, No.2, 2015.
(DOI: 10.1002/prp2.122,   PubMed: 26038698)
18.Kengo Nomura, Sawako Tatsumi, Atsumi Miyagawa, Yuji Shiozaki, Shohei Sasaki, Ichiro Kaneko, Mikiko Ito, Shinsuke Kido, Hiroko Segawa, Mitsue Sano, Tsutomu Fukuwatari, Katsumi Shibata and Ken-ichi Miyamoto :
Hepatectomy-related hypophosphatemia: a novel phosphaturic factor in the liver-kidney axis.,
Journal of the American Society of Nephrology, Vol.25, No.4, 761-772, 2014.
(DOI: 10.1681/ASN.2013060569,   PubMed: 24262791)
19.Shinsuke Kido, Marina Fujihara, Kengo Nomura, Shohei Sasaki, Rie Mukai, Ritsuko Ohnishi, Ichiro Kaneko, Hiroko Segawa, Sawako Tatsumi, Hiroto Izumi, Kimitoshi Kohno and Ken-ichi Miyamoto :
Molecular mechanisms of cadmium-induced fibroblast growth factor 23 upregulation in osteoblast-like cells.,
Toxicological Sciences, Vol.139, No.2, 301-316, 2014.
(DOI: 10.1093/toxsci/kfu043,   PubMed: 24614234,   Elsevier: Scopus)
20.Otoki Nakahashi, Hironori Yamamoto, Sarasa Tanaka, Mina Kozai, Yuichiro Takei, Masashi Masuda, Ichiro Kaneko, Yutaka Taketani, Masayuki Iwano, Ken-ichi Miyamoto and Eiji Takeda :
Short-term dietary phosphate restriction up-regulates ileal fibroblast growth factor 15 gene expression in mice.,
Journal of Clinical Biochemistry and Nutrition, Vol.54, No.2, 102-108, 2014.
(DOI: 10.3164/jcbn.13-109,   PubMed: 24688219)
21.Jui-Cheng Hsieh, C Rudolf Estess, Ichiro Kaneko, Kerr G Whitfield, W Peter Jurutka and R Mark Haussler :
Vitamin D receptor-mediated control of Soggy, Wise, and Hairless gene expression in keratinocytes.,
The Journal of Endocrinology, Vol.220, No.2, 165-178, 2014.
(DOI: 10.1530/JOE-13-0212,   PubMed: 24190897,   Elsevier: Scopus)
22.W Peter Jurutka, Ichiro Kaneko, Joanna Yang, S Jaskaran Bhogal, C Johnathon Swierski, R Christa Tabacaru, A Luis Montano, C Chanh Huynh, A Rabia Jama, D Ryan Mahelona, T Joseph Sarnowski, M Lisa Marcus, Alexis Quezada, Brittney Lemming, A Maria Tedesco, J Audra Fischer, A Said Mohamed, W Joseph Ziller, Ning Ma, M Geoffrey Gray, Arjan der Vaart van, A Pamela Marshall and E Carl Wagner :
Modeling, synthesis, and biological evaluation of potential retinoid X receptor (RXR) selective agonists: novel analogues of 4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydro-2-naphthyl)ethynyl]benzoic acid (bexarotene) and (E)-3-(3-(1,2,3,4-tetrahydro-1,1,4,4,6-pentamethylnaphthalen-7-yl)-4-hydroxyphenyl)acrylic acid (CD3254).,
Journal of Medicinal Chemistry, Vol.56, No.21, 8432-8454, 2013.
(DOI: 10.1021/jm4008517,   PubMed: 24180745,   Elsevier: Scopus)
23.K Rimpi Saini, Ichiro Kaneko, W Peter Jurutka, Ryan Forster, Antony Hsieh, Jui-Cheng Hsieh, R Mark Haussler and Kerr G Whitfield :
1,25-dihydroxyvitamin D(3) regulation of fibroblast growth factor-23 expression in bone cells: evidence for primary and secondary mechanisms modulated by leptin and interleukin-6.,
Calcified Tissue International, Vol.92, No.4, 339-353, 2012.
(DOI: 10.1007/s00223-012-9683-5,   PubMed: 23263654)
24.K Julie Furmick, Ichiro Kaneko, N Angela Walsh, Joanna Yang, S Jaskaran Bhogal, M Geoffrey Gray, C Juan Baso, O Drew Browder, S Jessica L Prentice, A Luis Montano, C Chanh Huynh, M Lisa Marcus, G Dorian Tsosie, S Jungeun Kwon, Alexis Quezada, M Nicole Reyes, Brittney Lemming, Puneet Saini, Arjan der Vaart van, L Thomas Groy, A Pamela Marshall, W Peter Jurutka and E Carl Wagner :
Modeling, synthesis and biological evaluation of potential retinoid X receptor-selective agonists: novel halogenated analogues of 4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydro-2-naphthyl)ethynyl]benzoic acid (bexarotene).,
ChemMedChem, Vol.7, No.9, 1551-1566, 2012.
(DOI: 10.1002/cmdc.201200319,   PubMed: 22927238)
25.A Pamela Marshall, Zachary Hernandez, Ichiro Kaneko, Tim Widener, Christa Tabacaru, Izayadeth Aguayo and W Peter Jurutka :
Discovery of novel vitamin D receptor interacting proteins that modulate 1,25-dihydroxyvitamin D3 signaling.,
The Journal of Steroid Biochemistry and Molecular Biology, Vol.132, No.1-2, 147-159, 2012.
(DOI: 10.1016/j.jsbmb.2012.05.001)
26.Shoji Kuwahara, Fumito Aranami, Hiroko Segawa, Akemi Onitsuka, Naoko Honda, Rieko Tominaga, Etsuyo Hanabusa, Ichiro Kaneko, Setsuko Yamanaka, Shohei Sasaki, Akiko Ohi, Kengo Nomura, Sawako Tatsumi, Shinsuke Kido, Mikiko Ito and Ken-ichi Miyamoto :
Identification and functional analysis of a splice variant of mouse sodium-dependent phosphate transporter Npt2c.,
The Journal of Medical Investigation : JMI, Vol.59, No.1-2, 116-126, 2012.
(Tokushima University Institutional Repository: 106008,   DOI: 10.2152/jmi.59.116,   PubMed: 22450000)
27.E Ryan Forster, W Peter Jurutka, Jui-Cheng Hsieh, A Carol Haussler, L Christine Lowmiller, Ichiro Kaneko, R Mark Haussler and G Whitfield Kerr :
Vitamin D receptor controls expression of the anti-aging klotho gene in mouse and human renal cells.,
Biochemical and Biophysical Research Communications, Vol.414, No.3, 557-562, 2011.
(DOI: 10.1016/j.bbrc.2011.09.117,   PubMed: 21982773)
28.Akiko Ohi, Etsuyo Hanabusa, Otoya Ueda, Hiroko Segawa, Naoshi Horiba, Ichiro Kaneko, Shoji Kuwahara, Tomo Mukai, Shohei Sasaki, Rieko Tominaga, Junya Furutani, Fumito Aranami, Shuichi Ohtomo, Yumiko Oikawa, Yousuke Kawase, A Naoko Wada, Takanori Tachibe, Mami Kakefuda, Hiromi Tateishi, Kaoru Matsumoto, Sawako Tatsumi, Shinsuke Kido, Naoshi Fukushima, Kou-Ichi Jishage and Ken-ichi Miyamoto :
Inorganic phosphate homeostasis in sodium-dependent phosphate cotransporter Npt2b+/- mice.,
American Journal of Physiology, Renal Physiology, Vol.301, No.5, F1105-13, 2011.
(DOI: 10.1152/ajprenal.00663.2010,   PubMed: 21816756)
29.Ichiro Kaneko, Hiroko Segawa, Junya Furutani, Shoji Kuwahara, Fumito Aranami, Etsuyo Hanabusa, Rieko Tominaga, Hector Giral, Yupanqui Caldas, Moshe Levi, Shigeaki Kato and Ken-ichi Miyamoto :
Hypophosphatemia in vitamin D receptor null mice: effect of rescue diet on the developmental changes in renal Na+ -dependent phosphate cotransporters.,
Pflügers Archiv : European Journal of Physiology, Vol.461, No.1, 77-90, 2010.
(DOI: 10.1007/s00424-010-0888-z,   PubMed: 21057807)
30.Yuka Tomoe, Hiroko Segawa, Kazuyo Shiozawa, Ichiro Kaneko, Rieko Tominaga, Etsuyo Hanabusa, Fumito Aranami, Junya Furutani, Shoji Kuwahara, Sawako Tatsumi, Mitsuru Matsumoto, Mikiko Ito and Ken-ichi Miyamoto :
Phosphaturic action of fibroblast growth factor 23 in Npt2 null mice,
American Journal of Physiology, Renal Physiology, Vol.298, No.6, F1341-F1350, 2010.
(DOI: 10.1152/ajprenal.00375.2009,   PubMed: 20357029)
31.Hiroko Segawa, Akemi Onitsuka, Junya Furutani, Ichiro Kaneko, Fumito Aranami, Natsuki Matsumoto, Yuka Tomoe, Masashi Kuwahata, Mikiko Ito, Mitsuru Matsumoto, Minqi Li, Norio Amizuka and Ken-ichi Miyamoto :
Npt2a and Npt2c in mice play distinct and synergistic roles in inorganic phosphate metabolism and skeletal development,
American Journal of Physiology, Renal Physiology, Vol.297, No.3, F671-678, 2009.
(DOI: 10.1152/ajprenal.00156.2009,   PubMed: 19570882)
32.Hiroko Segawa, Akemi Onitsuka, Masashi Kuwahata, Etsuyo Hanabusa, Junya Furutani, Ichiro Kaneko, Yuka Tomoe, Fumito Aranami, Natsuki Matsumoto, Mikiko Ito, Mitsuru Matsumoto, Minqi Li, Norio Amizuka and Ken-ichi Miyamoto :
Type IIc sodium dependent phosphate transporter regulates calcium metabolism,
Journal of the American Society of Nephrology, Vol.20, No.1, 104-113, 2009.
(DOI: 10.1681/ASN.2008020177,   PubMed: 19056871,   Elsevier: Scopus)
33.Yoshio Inoue, Hiroko Segawa, Ichiro Kaneko, Setsuko Yamanaka, Kenichiro Kusano, Eri Kawakami, Junya Furutani, Mikiko Ito, Masashi Kuwahata, Hitoshi Saito, Naoshi Fukushima, Shigeaki Kato, Hiro-omi Kanayama and Ken-ichi Miyamoto :
Role of the vitamin D receptor in FGF23 action on phosphate metabolism,
The Biochemical Journal, Vol.390, No.1, 325-331, 2005.
(DOI: 10.1042/BJ20041799,   PubMed: 15885032)
34.Hiroko Segawa, Ichiro Kaneko, Setsuko Yamanaka, Mikiko Ito, Masashi Kuwahata, Yoshio Inoue, Shigeaki Kato and Ken-ichi Miyamoto :
Intestinal Na-Pi cotransporter adaptation to dietary Pi content in vitamin D receptor null mice.,
American Journal of Physiology, Renal Physiology, Vol.287, No.1, F39-F47, 2004.
(DOI: 10.1152/ajprenal.00375.2003,   PubMed: 14996670)
35.Hiroko Segawa, Eri Kawakami, Ichiro Kaneko, Masashi Kuwahata, Mikiko Ito, Kenichiro Kusano, Hitoshi Saito, Naoshi Fukushima and Ken-ichi Miyamoto :
Effect of hydrolysis-resistant FGF23-R179Q on dietary phosphate regulation of the renal type-II Na/Pi transporter.,
Pflügers Archiv : European Journal of Physiology, Vol.446, No.5, 585-592, 2003.
(DOI: 10.1007/s00424-003-1084-1,   PubMed: 12851820)
36.Hiroko Segawa, Ichiro Kaneko, Akira Takahashi, Masashi Kuwahata, Mikiko Ito, Ohkido Ichiro, Sawako Tatsumi and Ken-ichi Miyamoto :
Growth-related renal Type II Na/Pi cotransporter.,
The Journal of Biological Chemistry, Vol.277, No.22, 19665-19672, 2002.
(DOI: 10.1074/jbc.M200943200,   PubMed: 11880379,   CiNii: 80015405488)

Review, Commentary:

1.Sawako Tatsumi, Kanako Katai, Ichiro Kaneko, Hiroko Segawa and Ken-ichi Miyamoto :
NAD metabolism and the SLC34 family: evidence for a liver-kidney axis regulating inorganic phosphate.,
Pflügers Archiv : European Journal of Physiology, Vol.471, No.1, 109-122, Sep. 2018.
(DOI: 10.1007/s00424-018-2204-2,   PubMed: 30218374)
2.Ichiro Kaneko, Ken-ichi Miyamoto and Takeshi Nikawa :
Vitamin D and muscle tissues,
Clinical Calcium, Vol.27, No.11, 63(1571)-70(1578), Oct. 2017.
3.Ichiro Kaneko, MS Sabir, CM Dussik, GK Whitfield, A Karrys, JC Hsieh, MR Haussler, MB Meyer, JW Pike and PW Jurutka :
活性型ビタミンDは,トリプトファン水酸化酵素およびレプチン遺伝子発現を制御する,
ビタミン, Vol.91, No.2, 132-134, Feb. 2017.
4.Ichiro Kaneko, Sawako Tatsumi, Hiroko Segawa and Ken-ichi Miyamoto :
Control of phosphate balance by the kidney and intestine.,
Clinical and Experimental Nephrology, Vol.21, No.Suppl 1, 21-26, Nov. 2016.
(DOI: 10.1007/s10157-016-1359-4,   PubMed: 27900568)
5.Ichiro Kaneko, Hironori Yamamoto, Kayo Ikuta, Sawako Tatsumi, Hiroko Segawa and Ken-ichi Miyamoto :
Transcriptional regulation of sodium-phosphate cotransporter gene expression.,
Molecular, Genetic, and Nutritional Aspects of Major and Trace Minerals, 437-445, Sep. 2016.
(DOI: 10.1016/B978-0-12-802168-2.00036-1)
6.MR Haussler, RK Saini, MS Sabir, CM Dussik, Z Khan, GK Whitfield, KP Griffin, Ichiro Kaneko and PW Jurutka :
Vitamin D Nutrient-Gene Interactions and Healthful Aging,
Molecular Basis of Nutrition and Aging, 441-461, Apr. 2016.
(DOI: 10.1016/B978-0-12-801816-3.00033-9)
7.Hiroko Segawa, Yuji Shiozaki, Ichiro Kaneko and Ken-ichi Miyamoto :
The Role of Sodium-Dependent Phosphate Transporter in Phosphate Homeostasis.,
Journal of Nutritional Science and Vitaminology, Vol.61 Suppl, S119-121, 2015.
(DOI: 10.3177/jnsv.61.S119,   PubMed: 26598821,   Elsevier: Scopus)
8.Ichiro Kaneko, Hiroko Segawa, Sawako Tatsumi and Ken-ichi Miyamoto :
[Genetic diseases of renal phosphate handling].,
Japanese Journal of Nephrology, Vol.57, No.4, 758-765, 2015.
(PubMed: 26126333,   Elsevier: Scopus)
9.Ichiro Kaneko, Hiroko Segawa, 辰巳 佐和子 and Ken-ichi Miyamoto :
Genetic diseases of renal phosphate handling,
Japanese Journal of Nephrology, Vol.57, No.4, 758-765, 2015.
(CiNii: 40020503207,   Elsevier: Scopus)
10.Shinsuke Kido, Ichiro Kaneko, Sawako Tatsumi, Hiroko Segawa and Ken-ichi Miyamoto :
Vitamin D and type II sodium-dependent phosphate cotransporters.,
Contributions to Nephrology, Vol.180, 86-97, May 2013.
(DOI: 10.1159/000346786,   PubMed: 23652552)
11.R Mark Haussler, Kerr G Whithfield, Ichiro Kaneko, A Carol Haussler, David Hsieh, Jui-Cheng Hsieh and W Peter Jurutka :
Molecular mechanisms of vitamin D action.,
Calcified Tissue International, Vol.92, No.2, 77-98, Jul. 2012.
(DOI: 10.1007/s00223-012-9619-0,   PubMed: 22782502,   Elsevier: Scopus)
12.R Mark Haussler, Kerr G Whitfield, Ichiro Kaneko, Ryan Forster, Rimpi Saini, Jui-Cheng Hsieh, A Carol Haussler and W Peter Jurutka :
The role of vitamin D in the FGF23, klotho, and phosphate bone-kidney endocrine axis.,
Reviews in Endocrine & Metabolic Disorders, Vol.13, No.1, 57-69, Mar. 2012.
(DOI: 10.1007/s11154-011-9199-8,   PubMed: 21932165,   Elsevier: Scopus)
13.Ken-ichi Miyamoto, Sakiko Haito-Sugino, Shoji Kuwahara, Akiko Ohi, Kengo Nomura, Mikiko Ito, Masashi Kuwahata, Shinsuke Kido, Sawako Tatsumi, Ichiro Kaneko and Hiroko Segawa :
Sodium-dependent phosphate cotransporters: lessons from gene knockout and mutation studies.,
Journal of Pharmaceutical Sciences, Vol.100, No.9, 3719-3730, May 2011.
(DOI: 10.1002/jps.22614,   PubMed: 21567407)
14.Hiroko Segawa, Fumito Aranami, Ichiro Kaneko, Yuka Tomoe and Ken-ichi Miyamoto :
The roles of Na/Pi-II transporters in phosphate metabolism.,
Bone, Vol.45 Suppl 1, S2-7, Feb. 2009.
(DOI: 10.1016/j.bone.2009.02.003,   PubMed: 19232403)

Proceeding of International Conference:

1.Sawako Tatsumi, Ichiro Kaneko, Hiroko Segawa and Ken-ichi Miyamoto :
Daily oscillation of the plasma inorganic phosphate concentration; Impact of Nampt deficient mice.,
ASN (American Society of Nephrology), Kidney Week 2018, Oct. 2018.
2.T Fujii, Hiroko Segawa, A Hamazaki, K Ikuta, A Kushi, Ichiro Kaneko, Sawako Tatsumi and Ken-ichi Miyamoto :
In Vivo Responses of Phosphorus-Based Food Additives with Different Forms,
American Society of Nephrology Kidney week., Nov. 2017.
3.Sawako Tatsumi, Miyagawa Atsumi, Fujii Osamu, Ogata Mao, Ichiro Kaneko, Hiroko Segawa and Ken-ichi Miyamoto :
Hepatectomy-Induced Hypophosphatemia: Mechanisms Underlying Downregulation of Phophate Transport in the Small Intestine.,
American Society of Nephrology. Kidney Week2016., Nov. 2016.
4.Ikuta Kayo, Hiroko Segawa, Yuki Shihoko, Ichiro Kaneko, Hanazaki Ai, Fujii Toru, Kushi Aoi, Sawako Tatsumi and Ken-ichi Miyamoto :
Salivary Pi Handling May Be under the Control of Gastrointestinal Pi Sensing.,
American Society of Nephrology.Kidney Week2016., Nov. 2016.
5.Ichiro Kaneko, Saini K. Rimpi, Witfield Kerr G., Ito Mikiko, Hiroko Segawa, Sawako Tatsumi, Ken-ichi Miyamoto, Haussler R. Mark and Jurutka W. Peter :
FGF23: A Nurr1-dependent Phosphaturic Hormone Gene That is Transcriptionally Regulated by 1,25-dihydroxyvitamin D,
XVIII International Congress on Nutrition and Metabolism in Renal Disease 2016, Apr. 2016.
6.Ichiro Kaneko, Saini K Rimpi, Whitfield G.Kerr, Mikiko Ito, Hiroko Segawa, Sawako Tatsumi, Ken-ichi Miyamoto, R.Haussler Mark and W.Jurutka Peter :
A Nurr1-dependent phosphaturic hormonegene that is transcriptionally regulated by 1.25-dihydroxyvitamin D.,
XVIII International Congress on Nutrition and Metabolism in Renal Desease(ICRNM2016), Apr. 2016.
7.Wagner E. Carl, Jurutka W. Peter, Marshall A. Pamela, Ichiro Kaneko, Shahani Pritika, Seto H. David, Varkey Julia, Hum L. Cindy, Sarnowski T. Joseph, Wentzel R. Michael and Chhun Christine :
Synthesis and Biological Characterization of Novel CD3254 Analogs,
American Chemical Society Annual Meeting, Mar. 2016.
8.Hanazaki Ai, Hiroko Segawa, Ikuta Kayo, Fujii Toru, Ichiro Kaneko, Yuki Shihoko, Nishiguchi Shiori, Notsu Keijiro, Shiozaki Yuji, Sawako Tatsumi and Ken-ichi Miyamoto :
Genetic Deletion of NaPi-2c Rescue Phenotype of klotho Knockout Mice wi thout Improving Severe Hyperphosphat emia.,
American Society of Nephrology Kidney week., Nov. 2015.
9.Yuki Shihoko, Hiroko Segawa, Sasaki Shohei, Ikuta Kayo, Ichiro Kaneko, Fujii Toru, Hanazaki Ai, Nishiguchi Shiori, Keijiro Notsu, Aki Eriko, Shiozaki Yuji, Sawako Tatsumi and Ken-ichi Miyamoto :
Disruption of intestinal alkaline phosphatase (Akp3) affects the phosphate homeostasis.,
ACN2015 Asian Congress of Nutrition., May 2015.
10.Haruna Sakaguchi, Sawako Tatsumi, Ogata Mao, Osamu Fujii, Arakaki Tomohiro, Miyagawa Atsumi, Nagamoto Kenta, Takahama Wako, Hirobata Yukiko, Yasui Akihiro, Ichiro Kaneko, Hiroko Segawa and Ken-ichi Miyamoto :
Bone-kidney axis regulating phosphate homeostasis: Study of osteocyte-ablated mice.,
ACN2015 Asian Congress of Nutrition., May 2015.
11.Ichiro Kaneko, Hsieh Jui-Cheng, Whitfield Kerr G., Hiroko Segawa, Ken-ichi Miyamoto, Haussler R. Mark and Jurutka W. Peter :
1,25-Dihydroxyvitamin D enhances human tryptophan hydroxylase gene expression through vitamin D responsive elements in human brain cells.,
12th Asian Congress of Nutrition 2015, May 2015.
12.Hiroko Segawa, Ichiro Kaneko, Yuji Shiozaki, Sawako Tatsumi and Ken-ichi Miyamoto :
The role of Na+-dependent Phosphate transporters in the body.,
ACN2015 Asian Congress of Nutrition., May 2015.
13.生田 かよ, Hiroko Segawa, 佐々木 祥平, Ichiro Kaneko, 塩崎 雄治, Sawako Tatsumi and Ken-ichi Miyamoto :
Inorganic Phosphate Handling in Salivary Glands.,
American Society of Nephrology (米国腎臓学会), ペ ンシルバニアコンベ ンションセンター(フィラデルフィア), Nov. 2014.

Proceeding of Domestic Conference:

1.Ichiro Kaneko, 瀬川 博子, 加藤 茂明 and 宮本 賢一 :
ビタミンDによる小腸リン輸送調節機序の解明,
第66回日本栄養改善学会学術総会, Sep. 2019.
2.Ichiro Kaneko, Haussler R. Mark, Jurutka W. Peter, Hiroko Segawa and Ken-ichi Miyamoto :
ビタミンDとうつ病の関係:セロトニン代謝の関係,
第7回日本腎栄養代謝研究会学術集会・総会, Jul. 2019.
3.Ichiro Kaneko :
リン・ビタミンD代謝における分子栄養学的研究,
第73回日本栄養・食糧学会大会, May 2019.
4.Ichiro Kaneko, Hiroko Segawa, 張 哲然, 加藤 茂明 and Ken-ichi Miyamoto :
ビタミンDが制御する小腸リン吸収機序の解明,
第3回CKD-MBD研究会学術集会・総会, Mar. 2019.
5.篠原 理沙, Sawako Tatsumi, Ichiro Kaneko, Hiroko Segawa and Ken-ichi Miyamoto :
骨細胞除去による無機リン代謝における影響:骨-腎臓-腸管連関の解析,
第57回日本栄養・食糧学会近畿支部会, Dec. 2018.
6.谷藤 和也, Hiroko Segawa, 生田 かよ, 花崎 愛, 佐々木 すみれ, 小池 萌, Ichiro Kaneko, 石川 康子 and Ken-ichi Miyamoto :
食物無機リン酸適応唾液-腸管-腎臓ネットワーク,
第51回日本栄養・食糧学会中国・四国支部大会, Nov. 2018.
7.Sawako Tatsumi, 齋 満帆, 中辻 翔也, 河田 美紀, 篠原 理沙, Ichiro Kaneko, Hiroko Segawa and Ken-ichi Miyamoto :
血中リン濃度を上げない食事時間とは?:動物モデルでの検討,
第6回日本腎栄養代謝研究会学術集会・総会, Jul. 2018.
8.Ken-ichi Miyamoto, Shinsuke Kido, Sawako Tatsumi, Ichiro Kaneko and Hiroko Segawa :
カドミウム暴露と骨軟化症:バイオマーカーの探索,
第5回日本栄養改善学会四国支部学術総会, Jun. 2018.
9.張 哲然, Ichiro Kaneko, Hiroko Segawa, 野津 圭二郎, 生田 かよ, 藤井 公, 花崎 愛, 加藤 茂明 and Ken-ichi Miyamoto :
ビタミンDによる小腸リン吸収促進機構の解明,
第5回日本栄養改善学会四国支部学術総会, Jun. 2018.
10.Ichiro Kaneko, Hiroko Segawa, 野津 圭二郎, 生田 かよ, 藤井 公, 花崎 愛, 張 哲然, 加藤 茂明 and Ken-ichi Miyamoto :
ビタミンDが制御する腸管リン吸収機序の解明,
日本ビタミン学会第70回大会, Jun. 2018.
11.Ichiro Kaneko, Hiroko Segawa, 野津 圭二郎, 生田 かよ, 藤井 公, 花崎 愛, 張 哲然, 加藤 茂明 and Ken-ichi Miyamoto :
ビタミンDが制御する腸管リン吸収機序の解明,
第72回日本栄養・食糧学会大会, May 2018.
12.Hiroko Segawa, 古谷 順也, Ichiro Kaneko and Ken-ichi Miyamoto :
Regulation of intestinal nitrogen absorption by FGF23/phosphate,
第2回日本UremicToxin 研究学術集会, Apr. 2018.
13.Hiroko Segawa, Ichiro Kaneko and Ken-ichi Miyamoto :
腎臓と他の臓器相関による生体内リン代謝調節機構,
第95回日本生理学会大会, Mar. 2018.
14.Sawako Tatsumi, 篠原 理沙, Ichiro Kaneko, Hiroko Segawa and Ken-ichi Miyamoto :
ミネラル代謝における骨細胞減少の効果:骨細胞-腎臓-腸管連関制御,
第72回日本栄養・食糧学会大会, Nov. 2017.
15.Ichiro Kaneko, G K.Saini Rimpi, Whitfield Kerr, Mikiko Ito, Hiroko Segawa, Sawako Tatsumi, Ken-ichi Miyamoto, R.Haussler Mark and W.Jurutka Peter :
リン利尿因子FGF23の転写調節機序の解明,
第50回日本栄養・食糧学会 中国・四国支部大会, Nov. 2017.
16.木下 瑛美, Sawako Tatsumi, 藤井 理, 張 哲然, Ichiro Kaneko, Hiroko Segawa and Ken-ichi Miyamoto :
腸管NAD+合成律速酵素(Nampt)と全身性NAD+代謝,
第50回日本栄養・食糧学会 中国・四国支部大会, Nov. 2017.
17.佐々木 すみれ, Hiroko Segawa, 桐野 留里, Ichiro Kaneko, Sawako Tatsumi and Ken-ichi Miyamoto :
形態の異なるリン化合物接種に対する生体への影響,
第64回日本栄養改善学会学術総会, Sep. 2017.
18.桐野 留里, Hiroko Segawa, 佐々木 すみれ, Ichiro Kaneko, Sawako Tatsumi and Ken-ichi Miyamoto :
生体内リン恒常性における腸管アルカリフォスファターゼの役割,
第64回日本栄養改善学会学術総会, Sep. 2017.
19.Ichiro Kaneko, Hiroko Segawa, Sawako Tatsumi and Ken-ichi Miyamoto :
脳機能における活性型ビタミンDの役割,
第64回日本栄養改善学会学術総会, Sep. 2017.
20.藤井 理, Sawako Tatsumi, Ichiro Kaneko, Hiroko Segawa and Ken-ichi Miyamoto :
水溶性ビタミンB3と腸管上皮機能,
第64回日本栄養改善学会学術総会, Sep. 2017.
21.桐野 留里, Hiroko Segawa, Ichiro Kaneko, Sawako Tatsumi and Ken-ichi Miyamoto :
生体内リン恒常性におけるアルカフォスファターゼの役割,
第4回日本栄養改善学会四国支部学術総会, Jun. 2017.
22.Hiroko Segawa, 佐々木 祥平, 結城 志帆子, Ichiro Kaneko, Sawako Tatsumi and Ken-ichi Miyamoto :
The role of intestinal alkaline phosphatase on phosphate homeostasis.,
第71回日本栄養·食糧学会大会, May 2017.
23.Sawako Tatsumi, 緒方 雅央, 新垣 友啓, 藤井 理, Ichiro Kaneko, Hiroko Segawa and Ken-ichi Miyamoto :
骨ー腎臓連関を介した食餌性リン感受機Sensing of dietary phosphate loading in the bone-kidney axis.,
第71回日本栄養·食糧学会大会, May 2017.
24.Hiroko Segawa, Ichiro Kaneko, Sawako Tatsumi and Ken-ichi Miyamoto :
Nutrient transporter and Health/Disease [Intestinal Phosphate absorption and Chronic Kidney Disease],
第71回日本栄養·食糧学会大会, May 2017.
25.Hiroko Segawa, 佐々木 祥平, 結城 志帆子, Ichiro Kaneko, Sawako Tatsumi and Ken-ichi Miyamoto :
生体内リン恒常性におけるIntestinal Alkaline Phosphatase(IAP)の役割,
第1回CKD‐MBD研究会学術集会・総会, Mar. 2017.
26.高濱 和子, Sawako Tatsumi, 宮川 淳美, 藤井 理, 新垣 友啓, 緒方 雅央, 木下 瑛美, Ichiro Kaneko, Hiroko Segawa and Ken-ichi Miyamoto :
リン代謝動態の概日リズム形成機序解明,
第49回日本栄養・食糧学会 中国・四国支部大会, Nov. 2016.
27.Ichiro Kaneko, Hsieh Jui-Cheng, Whitfield Kerr G., Sawako Tatsumi, Hiroko Segawa, Ken-ichi Miyamoto, Haussler R. Mark and Jurutka W. Peter :
脳機能におけるビタミンDの役割,
日本ビタミン学会誌, Jun. 2016.
28.Ichiro Kaneko, Hsieh Jui-Cheng, Whitfield Kerr G., Sawako Tatsumi, Hiroko Segawa and Ken-ichi Miyamoto :
脳機能におけるビタミンDの役割,
第68回日本ビタミン学会, Jun. 2016.
29.川端 優佳, Hiroko Segawa, 結城 志帆子, 中山 彰吾, 藤井 公, 生田 かよ, 花崎 愛, 野津 圭二郎, 西口 詩織, Ichiro Kaneko, Sawako Tatsumi and Ken-ichi Miyamoto :
形態の異なるリン化合物接種に対する生体への影響,
第70回日本栄養・食糧学会大会, May 2016.
30.Hiroko Segawa, 佐々木 祥平, 結城 志帆子, Ichiro Kaneko, Sawako Tatsumi and Ken-ichi Miyamoto :
生体内リン恒常性におけるIntestinal Alkaline Phosphatase(IAP)の役割,
第1回CKD‐MBD研究会学術集会・総会, Mar. 2016.
31.Ichiro Kaneko, Jui-Cheng Hsieh, G.Kerr Whitfield, Sawako Tatsumi, Hiroko Segawa, Ken-ichi Miyamoto, R Mark Haussler and W Peter Jurutka :
脳機能におけるビタミンDの役割について,
第19会日本病態栄養学会年次学術集会, Jan. 2016.
32.西口 詩織, Hiroko Segawa, 蓑島 さくら, 桑原 煩治, Ichiro Kaneko, 前田 彰, Sawako Tatsumi and Ken-ichi Miyamoto :
リン血症是正に対するFGF23/Klothoシグナルの解明,
第19会日本病態栄養学会年次学術集会, Jan. 2016.
33.新垣 友啓, Sawako Tatsumi, 緒方 雅央, 阪口 晴菜, 安井 朗洋, 藤井 理, 永元 健太, Ichiro Kaneko, Hiroko Segawa and Ken-ichi Miyamoto :
骨細胞の減少による胆汁酸代謝異常についての解析.,
第19会日本病態栄養学会年次学術集会., Jan. 2016.
34.生田 かよ, Hiroko Segawa, 結城 志帆子, Ichiro Kaneko, 西口 詩織, Yasuko Ishikawa, 上田 乙也, 堀場 直, 寺社下 浩一, 福島 直 and Ken-ichi Miyamoto :
生体内リン代謝調節機構における唾液腺の関与.,
第38回日本分子生物学会年会・第88回日本生化学会大会 合同大会, Dec. 2015.
35.花崎 愛, Hiroko Segawa, 福尾 真理, Ichiro Kaneko, Sawako Tatsumi and Ken-ichi Miyamoto :
Klotho and NaPi-2c,double deletionから導くNaPi-2cの重要性.,
第48回日本栄養・食糧学会中国・四国支部大会, Oct. 2015.
36.Hiroko Segawa, Ichiro Kaneko and Ken-ichi Miyamoto :
慢性腎臓病におけるリンコントロール.,
第31回日本DDS学会学術集会., Jul. 2015.
37.Hiroko Segawa, 生田 かよ, 塩崎 雄治, Ichiro Kaneko and Ken-ichi Miyamoto :
Gastrointestinal phosphate handling.,
上皮バリア・輸送に関するシンポジウム, Nov. 2014.
38.緒方 雅央, Sawako Tatsumi, 藤井 理, 阪口 晴菜, 新垣 友啓, 宮川 淳美, 永元 健太, 高濱 和子, 廣畠 佑希子, Ichiro Kaneko, Hiroko Segawa and Ken-ichi Miyamoto :
骨細胞除去マウスのカルシウム/リン代謝異常解析について,
第47回日本栄養・食糧学会 中国・四国支部大会, Oct. 2014.

Et cetera, Workshop:

1.Ichiro Kaneko, Hiroko Segawa, 張 哲然, 加藤 茂明 and Ken-ichi Miyamoto :
ビタミン D が制御する小腸リン吸収機序の解明,
第3回日本CKD-MBD研究会 学術集会・総会, Mar. 2019.
2.Sawako Tatsumi, Ichiro Kaneko, Hiroko Segawa and Ken-ichi Miyamoto :
骨細胞除去によるミネラル代謝への影響: 骨 - 腎臓 - 腸管連関の解析,
第3回日本CKD-MBD研究会 学術集会・総会, Mar. 2019.
3.Ken-ichi Miyamoto, Shinsuke Kido, Sawako Tatsumi, Ichiro Kaneko and Hiroko Segawa :
カドミウム暴露と骨軟化症:バイオマーカーの探索,
第5回日本栄養改善学会四国支部学術総会, Jun. 2018.
4.Sawako Tatsumi, 篠原 理沙, Ichiro Kaneko, Hiroko Segawa and Ken-ichi Miyamoto :
ミネラル代謝における骨細胞減少の効果:骨細胞-腎臓-腸管連関制御,
第72回日本栄養・食糧学会大会, May 2018.

Grants-in-Aid for Scientific Research (KAKEN Grants Database @ NII.ac.jp)

  • 腎・骨格筋dual維持機構を介した慢性腎臓病の栄養療法 (Project/Area Number: 18K17966 )
  • 無機リン酸(リン)応答複合体機能の解明とリン過剰克服に向けた新戦略 (Project/Area Number: 17H04190 )
  • Clarification of multi-organ communication controlling with phosphate and vitamin D metabolism. (Project/Area Number: 15K19455 )
  • Search by Researcher Number (40389515)