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Tokushima University ⟩ University Hospital ⟩ Clinical Division ⟩ Department of Internal Medicine ⟩ Respiratory and Rheumatology Medicine ⟩ (Files for researchmap) [PDF manual] [Auto-propagate to researchmap]

Research

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Academic Paper (Judged Full Paper):

1. Yuya Yamashita, Seidai Satou, Kaori Nii, Kensuke Mori, Keiko Haji, Nobuhito Naito, Hirokazu Ogino, Hiroshi Kawano, Masaki Hanibuchi, Itsuro Endo and Yasuhiko Nishioka :
Isolated adrenocorticotropic hormone deficiency presenting with arthritis: A case report,
Modern Rheumatology Case Reports, Vol.9, No.1, 10-14, 2025.
(DOI: 10.1093/mrcr/rxae057,   PubMed: 39361145,   Elsevier: Scopus)
2. Seidai Satou, Kazuya Koyama, Hirohisa Ogawa, Kojin Murakami, Takeshi Imakura, Yuya Yamashita, Kozo Kagawa, Hiroshi Kawano, Eiji Hara and Yasuhiko Nishioka :
A novel BRD4 degrader, ARV-825, attenuates lung fibrosis through senolysis and antifibrotic effect.,
Respiratory Investigation, Vol.61, No.6, 781-792, 2023.
(DOI: 10.1016/j.resinv.2023.08.003,   PubMed: 37741093)
3. Takeshi Imakura, Seidai Satou, Kazuya Koyama, Hirohisa Ogawa, Takahiro Niimura, Kojin Murakami, Yuya Yamashita, Keiko Haji, Nobuhito Naito, Kozo Kagawa, Hiroshi Kawano, Yoshito Zamami, Keisuke Ishizawa and Yasuhiko Nishioka :
A polo-like kinase inhibitor identified by computational repositioning attenuates pulmonary fibrosis.,
Respiratory Research, Vol.24, No.1, 148, 2023.
(Tokushima University Institutional Repository: 2011774,   DOI: 10.1186/s12931-023-02446-x,   PubMed: 37269004)
4. Kozo Kagawa, Seidai Satou, Kazuya Koyama, Takeshi Imakura, Kojin Murakami, Yuya Yamashita, Nobuhito Naito, Hirohisa Ogawa, Hiroshi Kawano and Yasuhiko Nishioka :
The lymphocyte-specific protein tyrosine kinase-specific inhibitor A-770041 attenuates lung fibrosis via the suppression of TGF-β production in regulatory T-cells.,
PLoS ONE, Vol.17, No.10, e0275987, 2022.
(Tokushima University Institutional Repository: 2011525,   DOI: 10.1371/journal.pone.0275987,   PubMed: 36301948)
5. Nobuhito Naito, Hiroshi Kawano, Yuya Yamashita, Mayo Kondou, Shotaro Haji, Ryosuke Miyamoto, Yuko Toyoda, Yasuhisa Kanematsu, Yuishin Izumi, Yoshimi Bando and Yasuhiko Nishioka :
Neuropsychiatric systemic lupus erythematosus with cerebellar vasculitis and obstructive hydrocephalus requiring decompressive craniectomy.,
Modern Rheumatology Case Reports, Vol.5, No.1, 52-57, 2020.
(DOI: 10.1080/24725625.2020.1826626,   PubMed: 33021438)
6. Yuko Toyoda, Kazuya Koyama, Hiroshi Kawano, Haruka Nishimura, Kozo Kagawa, Shun Morizumi, Nobuhito Naito, Seidai Satou, Yuya Yamashita, Naoki Takahashi, Hisatsugu Goto, Masahiko Azuma and Yasuhiko Nishioka :
Clinical features of interstitial pneumonia associated with systemic lupus erythematosus.,
Respiratory Investigation, Vol.57, No.5, 435-443, 2019.
(DOI: 10.1016/j.resinv.2019.04.005,   PubMed: 31235450)
7. Hiroyuki Kozai, Yuko Toyoda, Hisatsugu Goto, Jun Kishi, Makoto Tobiume, Yuya Yamashita, Haruka Nishimura, Mayo Kondou, Hiroshi Kawano and Yasuhiko Nishioka :
A case of interstitial pneumonia associated with anti-PL-7 antibody in a patient with rheumatoid arthritis.,
The Journal of Medical Investigation : JMI, Vol.65, No.1,2, 147-150, 2018.
(Tokushima University Institutional Repository: 2004633,   DOI: 10.2152/jmi.65.147,   PubMed: 29593187,   CiNii: 1390282679224622464,   Elsevier: Scopus)

Proceeding of International Conference:

1. Seidai Satou, Kazuya Koyama, Hirohisa Ogawa, Murakami Kojin, Yuya Yamashita, Danzan NandinErdene, Bando Hiroki, Keiko Haji, Nobuhito Naito, Hiroshi Kawano, Eiji Hara and Yasuhiko Nishioka :
A novel senolytic drug, ARV-825, ameliorates experimental lung fibrosis,
ERS International Congress 2023, Milano, Sep. 2023.
2. Hiroki Bando, Seidai Satou, Hirohisa Ogawa, Kazuya Koyama, Murakami Kojin, Yuya Yamashita, Danzan Nandin-Erdene, Keiko Haji, Nobuhito Naito, Hiroshi Kawano and Yasuhiko Nishioka :
Anamorelin, a ghrelin receptor agonist, inhibited the allergic airway inflammation in mice,
ERS International Congress 2023, Milano, Sep. 2023.
3. Murakami Kojin, Nishimura Haruka, Hiroshi Kawano, Danzan Nandin-Erdene, Yuya Yamashita, Keiko Haji, Nobuhito Naito, Kazuya Koyama, Seidai Satou and Yasuhiko Nishioka :
Analysis of the Anti-fibrotic Potential of JAK Inhibitors in a Bleomycin-induced Pulmonary Fibrosis Model,
ATS 2023, Washington, DC, May 2023.
4. Kazuya Koyama, Seidai Satou, Hiroshi Kawano, Hiroshi Kawano, Atsushi Mitsuhashi, Murakami Kojin, Yuya Yamashita, Keiko Haji, Kozo Kagawa, Hirohisa Ogawa and Yasuhiko Nishioka :
Evaluation of fibrocytes in silica-induced and bleomycin-induced pulmonary fibrosis model in mice by single cell RNA-seq analysis,
APSR 2022, Seoul, Nov. 2022.
5. Imakura Takeshi, Seidai Satou, Kazuya Koyama, Hirohisa Ogawa, Takahiro Niimura, Murakami Kojin, Yuya Yamashita, Keiko Haji, Nobuhito Naito, Kozo Kagawa, Hiroshi Kawano, Yoshito Zamami, Keisuke Ishizawa and Yasuhiko Nishioka :
Computational drug repositioning and wet-lab validation approach identifies polo-like kinase inhibitors as potential therapeutics for pulmonary fibrosis,
ERS International Congress 2022, Barcelona, Sep. 2022.
6. Seidai Satou, Kazuya Koyama, Hirohisa Ogawa, Kojin Murakami, Takeshi Imakura, Yuya Yamashita, Keiko Haji, Kozo Kagawa, Hiroshi Kawano, Eiji Hara and Yasuhiko Nishioka :
A Novel Senolytic Agent, ARV-825, Ameliorates Bleomycin-InducedPulmonary Fibrosis in Mice,
ATS 2022 International Conference, San Francisco, May 2022.
7. Takeshi Imakura, Seidai Satou, Kazuya Koyama, Hirohisa Ogawa, Takahiro Niimura, Kojin Murakami, Yuya Yamashita, Keiko Haji, Nobuhito Naito, Kozo Kagawa, Hiroshi Kawano, Yoshito Zamami, Keisuke Ishizawa and Yasuhiko Nishioka :
Computational Drug Repositioning Approach Identifies Polo-Like KinaseInhibitors as Potential Therapeutics for Pulmonary Fibrosis,
ATS 2022 International Conference, San Francisco, May 2022.
8. Kazuya Koyama, Hiroshi Kawano, Atsushi Mitsuhashi, Kojin Murakami, Takeshi Imakura, Yuya Yamashita, Keiko Haji, Kozo Kagawa, Seidai Satou, Hirohisa Ogawa and Yasuhiko Nishioka :
Single Cell RNA-seq Analysis of Fibrocytes in Silica Induced Mouse Pulmonary Fibrosis Model,
ATS 2022 International Conference, San Francisco, May 2022.
9. Imakura Takeshi, Seidai Satou, Kazuya Koyama, Takahiro Niimura, Kohjin Murakami, Yuya Yamashita, Takahashi Naoki, Nobuhito Naito, Kozo Kagawa, Hiroshi Kawano, Yoshito Zamami, Keisuke Ishizawa and Yasuhiko Nishioka :
Polo-like kinase inhibitors identified by computational repositioning attenuates bleomycin-induced pulmonary fibrosis in mice,
APSR 2021, Kyoto and online, Nov. 2021.
10. Kohjin Murakami, Takahashi Naoki, Seidai Satou, Imakura Takeshi, Yuya Yamashita, Kozo Kagawa, Kazuya Koyama, Hiroshi Kawano, Tanigawara Kazuaki, Toriumi Wataru and Yasuhiko Nishioka :
Therapeutic effect of oligonucleotide therapeutics PK-7010 in mouse model of bleomycin-induced lung fibrosis,
APSR 2021, Kyoto and online, Nov. 2021.
11. Nobuhito Naito, Hiroshi Kawano, Imakura Takeshi, Yuya Yamashita, Kohjin Murakami, Kozo Kagawa, Kazuya Koyama, Seidai Satou, Hiroshi Nokihara, Inagaki Yutaka and Yasuhiko Nishioka :
Development of improved method to identify and analyze lung fibrocytes with flow cytometry in a reporter mouse strain,
APSR 2021, Kyoto and online, Nov. 2021.
12. Kozo Kagawa, Kazuya Koyama, Seidai Satou, Imakura Takeshi, Kohjin Murakami, Yuya Yamashita, Takahashi Naoki, Nobuhito Naito, Hiroshi Kawano and Yasuhiko Nishioka :
A Lck-specific inhibitor, A-770041, attenuates pulmonary fibrosis via the suppression of TGF-b production in regulatory T cells,
APSR 2021, Kyoto and online, Nov. 2021.
(DOI: 10.1111/resp.14150_945)
13. Hiroshi Kawano, Nishimura Haruka, Imakura Takeshi, Yuya Yamashita, Kohjin Murakami, Nobuhito Naito, Kozo Kagawa, Kazuya Koyama, Seidai Satou, Hiroshi Nokihara and Yasuhiko Nishioka :
Analysis of anti-fibrotic potential of JAK inhibitors in bleomycin-induced pulmonary fibrosis model,
APSR 2021, Kyoto and online, Nov. 2021.
(DOI: 10.1111/resp.14150_915)
14. Kazuya Koyama, Hiroshi Kawano, Yuya Yamashita, Imakura Takeshi, Takahashi Naoki, Nobuhito Naito, Seidai Satou and Yasuhiko Nishioka :
Clinical Features of the Acute Exacerbation of Rheumatoid Arthritis-Associated Interstitial Lung Disease,
ATS 2021, 米国(WEB), May 2021.

Proceeding of Domestic Conference:

1. Yuya Yamashita, Hiroshi Kawano, Katsuhiro Atagi, Kojin Murakami, Nobuhito Naito, Seidai Satou and Yasuhiko Nishioka :
リウマチモデルにおけるPLK阻害療法の治療効果,
第68回日本リウマチ学会総会・学術集会, Apr. 2024.
2. 山本 浩生, Hiroki Bandoh, Keiko Haji, Yuya Yamashita, Nobuhito Naito, Seidai Satou, Hiroshi Kawano, Masaki Hanibuchi and Yasuhiko Nishioka :
ステロイド抵抗性の気道病変に対してシクロホスファミドが著効した再発性多発軟骨炎の1例,
第129回日本内科学会四国地方会, Dec. 2023.
3. Hiroshi Kawano, Yu Aoi, Katsuhiro Atagi, Kojin Murakami, Yuya Yamashita, Nobuhito Naito, Hirokazu Ogino, Seidai Satou and Yasuhiko Nishioka :
顕微鏡的多発血管炎の診断時にEBVの再活性化を呈し，リツキシマブにて寛解導入療法を行った1例,
第34回日本リウマチ学会中国・四国支部学術集会, Dec. 2023.
4. Yu Aoi, Hiroshi Kawano, Katsuhiro Atagi, Kojin Murakami, Yuya Yamashita, Nobuhito Naito, Hirokazu Ogino, Seidai Satou and Yasuhiko Nishioka :
胸膜炎，間質性肺疾患を先行し，発熱性好中球減少症と肺病変の増悪で発症したSLEの1例,
第34回日本リウマチ学会中国・四国支部学術集会, Dec. 2023.
5. Hiroki Bandoh, Seidai Satou, Kojin Murakami, Yuya Yamashita, Nobuhito Naitoh, Kazuya Koyama, Hiroshi Kawano, Hirohisa Ogawa and Yasuhiko Nishioka :
グレリン受容体作動薬アナモレリンのアレルギー性気道炎症モデルマウスにおける検討,
第72回日本アレルギー学会学術大会, Oct. 2023.
6. Seidai Satou, Hirohisa Ogawa, Kojin Murakami, Yuya Yamashita, Keiko Haji, Hiroshi Kawano, Eiji Hara and Yasuhiko Nishioka :
BRD4 阻害剤 ARV825 の線維化関連遺伝子の発現抑制と老化細胞除去を介した抗線維化効果の検討,
第3回日本びまん性肺疾患研究会, Sep. 2023.
7. Keiko Haji, Seidai Satou, Hirohisa Ogawa, Kojin Murakami, Yuya Yamashita, Kazuya Koyama, Hiroshi Kawano, 小林 克利, 諸星 俊郎 and Yasuhiko Nishioka :
オートタキシン阻害作用を有する 2ccPA の肺線維症における有効性の検討,
第3回日本びまん性肺疾患研究会, Sep. 2023.
8. Hiroki Bandoh, Seidai Satou, Kojin Murakami, Yuya Yamashita, Nobuhito Naito, Kazuya Koyama, Hiroshi Kawano, Hirohisa Ogawa and Yasuhiko Nishioka :
グレリン受容体作動薬アナモレリンのアレルギー性気道炎症モデルマウスにおける検討,
第63回日本呼吸器学会学術講演会, Apr. 2023.
9. Kojin Murakami, Seidai Satou, Yuya Yamashita, Keiko Haji, 坂東 弘基, Nobuhito Naito, Kazuya Koyama, Hiroshi Kawano, 稲村 典昭, 蓮見 惠司 and Yasuhiko Nishioka :
新規可溶性エポキシヒドロラーゼ阻害薬SMTP-44Dの肺線維症に対する有効性の検討,
第63回日本呼吸器学会学術講演会, Apr. 2023.
10. Hiroshi Kawano, 小路 貴俊, Katsuhiro Atagi, Kojin Murakami, Yuya Yamashita, Nobuhito Naito, Hirokazu Ogino, Seidai Satou and Yasuhiko Nishioka :
リンパ球特異的チロシンキナーゼ阻害薬A-770041は制御性T細胞によるTGF-βs産生抑制を介して肺線維症を改善する,
第67回日本リウマチ学会総会・学術集会, Apr. 2023.
11. 新居 香織, Keiko Haji, Yu Aoi, Yuya Yamashita, Nobuhito Naito, Hirokazu Ogino, Hiroshi Kawano, Seidai Satou, Masaki Hanibuchi and Yasuhiko Nishioka :
関節炎を呈したACTH 単独欠損症の1例,
第127回日本内科学会四国地方会, Dec. 2022.
12. 寺澤 翠, Keiko Haji, 市原 聖也, Yuya Yamashita, Asami Fukuya, Nobuhito Naito, Hiroto Yoneda, Kozo Kagawa, Hirokazu Ogino, Hiroshi Kawano, Seidai Satou, Masaki Hanibuchi and Yasuhiko Nishioka :
抗PD-L1抗体投与後に顕在化した抗ARS抗体陽性間質性肺炎の1例,
第67回日本呼吸器学会中国・四国地方会, Dec. 2022.
13. 小路 貴俊, Nobuhito Naito, Hiroshi Kawano, Kojin Murakami, Yuya Yamashita, 美馬 正人, Hirokazu Ogino, Seidai Satou and Yasuhiko Nishioka :
両側声帯麻痺を呈した多発血管炎性肉芽腫症に伴う肥厚性硬膜炎の1例,
第33回日本リウマチ学会中国・四国支部学術集会, Dec. 2022.
14. Katsuhiro Atagi, Hiroshi Kawano, 小路 貴俊, Kojin Murakami, Yuya Yamashita, 美馬 正人, Nobuhito Naito, Hirokazu Ogino, Seidai Satou and Yasuhiko Nishioka :
劇症1型糖尿病と同時期に発症した両側特発性外眼筋炎の1例,
第33回日本リウマチ学会中国・四国支部学術集会, Dec. 2022.
15. Nobuhito Naito, 西村 春佳, Yuya Yamashita, Kojin Murakami, Keiko Haji, Kazuya Koyama, Hirokazu Ogino, Seidai Satou, Hiroshi Kawano, Masaki Hanibuchi and Yasuhiko Nishioka :
ブレオマイシン誘発肺線維症モデルマウスを用いたJAK阻害薬の抗線維化効果についての検討,
第50回日本臨床免疫学会総会, Oct. 2022.
16. Hiroshi Kawano, Takeshi Imakura, Yuya Yamashita, Kojin Murakami, Nobuhito Naito, Seidai Satou and Yasuhiko Nishioka :
ブレオマイシン誘発肺線維症モデルマウスにおけるJAK阻害薬の抗線維化効果に関する検討,
第66回日本リウマチ学会総会・学術集会, Apr. 2022.
17. Seidai Satou, Kazuya Koyama, Hirohisa Ogawa, Kojin Murakami, Takeshi Imakura, Yuya Yamashita, Hiroshi Kawano, Eiji Hara and Yasuhiko Nishioka :
Antifibrotic and senolytic activity of novel BRD4 degrader ARV825 in experimental model of lung fibrosis,
The 62nd Annual Meeting of the Japanese Respiratory Society, Apr. 2022.
18. 美馬 正人, Seidai Satou, 原田 紗希, 鈴江 涼子, Yuya Yamashita, Ryohiko Ozaki, Keiko Haji, Nobuhito Naito, Hiroshi Kawano, Hiroshi Nokihara and Yasuhiko Nishioka :
抗ARS抗体陽性間質性肺疾患の胸部画像所見の検討,
第62回日本呼吸器学会学術講演会, Apr. 2022.
19. Takeshi Imakura, Seidai Satou, Kazuya Koyama, Takahiro Niimura, Kojin Murakami, Yuya Yamashita, Keiko Haji, Kozo Kagawa, Hiroshi Kawano, Yoshito Zamami, Keisuke Ishizawa and Yasuhiko Nishioka :
In silico解析により同定されたPLK阻害剤のブレオマイシン誘発肺線維症モデルマウスにおける効果の検討,
第62回日本呼吸器学会学術講演会, Apr. 2022.
20. 石田 卓也, Hiroshi Kawano, Takeshi Imakura, Kohjin Murakami, Yuya Yamashita, 美馬 正人, Nobuhito Naito, Hirokazu Ogino, Seidai Satou and Yasuhiko Nishioka :
当院における膠原病関連間質性肺疾患に対するニンテダニブの使用経験,
第32回日本リウマチ学会中国・四国支部学術集会, Dec. 2021.
21. 市原 聖也, Hiroshi Kawano, Takeshi Imakura, Kohjin Murakami, Yuya Yamashita, 美馬 正人, Nobuhito Naito, Hirokazu Ogino, Seidai Satou and Yasuhiko Nishioka :
再発性多発軟骨炎治療中の不明熱精査でUBA1遺伝子解析により診断したVEXAS症候群の1例,
第32回日本リウマチ学会中国・四国支部学術集会, Dec. 2021.
22. 石田 卓也, YABUKI Yohhei, Kozo Kagawa, Yuya Yamashita, Hirokazu Ogino, Seidai Satou, Hiroshi Kawano, Hiroshi Nokihara and Yasuhiko Nishioka :
成人Still病との鑑別を要した家族性地中海熱非典型例の1例,
第125回日本内科学会四国地方会, Dec. 2021.
23. Kohjin Murakami, Naoki Takahashi, Seidai Satou, Takeshi Imakura, Yuya Yamashita, Kozo Kagawa, Kazuya Koyama, Hiroshi Kawano, 谷川原 万顕, 鳥海 亙 and Yasuhiko Nishioka :
ブレオマイシン誘発肺線維症モデルマウスにおける新規核酸医薬の有効性の検討,
第1回日本びまん性肺疾患研究会, Oct. 2021.
24. 花房 翠, YABUKI Yohhei, Takeshi Imakura, Hiroto Yoneda, Akane Abe, 美馬 正人, Yuya Yamashita, Nobuhito Naito, Kozo Kagawa, Kenji Otsuka, Seidai Satou, Hiroshi Nokihara and Yasuhiko Nishioka :
ステロイドパルス療法後に増悪し二度目のパルス療法が奏効したCOVID-19肺炎の1例,
第63回日本呼吸器学会中国・四国地方会, Aug. 2021.
25. Yuya Yamashita, Takeshi Imakura, Naoki Takahashi, Nobuhito Naito, Seidai Satou, Hiroshi Kawano and Yasuhiko Nishioka :
関節リウマチに伴う間質性肺炎急性増悪の臨床的特徴 ∼特発性肺線維症急性増悪との比較検討∼,
第65回日本リウマチ学会総会・学術集会, Apr. 2021.
26. Yuya Yamashita, Nobuhito Naito, 原田 紗希, 今倉 健, 髙橋 直希, Seidai Satou, Hiroshi Kawano and Yasuhiko Nishioka :
ST合剤による無菌性髄膜炎を呈したシェーグレン症候群の一例,
第31回日本リウマチ学会中国・四国支部学術集会, Dec. 2020.
27. Hiroshi Kawano, Yuya Yamashita, Nobuhito Naito, Seidai Satou, Muneyuki Kadota, Takayuki Ise, Shusuke Yagi, Masataka Sata, Hiroshi Nokihara and Yasuhiko Nishioka :
高安動脈炎による難治性皮膚潰瘍に対してべペルミノゲン ペルプラスミド(ヒト肝細胞増殖因子プラスミドベクター)投与が奏効した1例,
第48回日本臨床免疫学会総会, Oct. 2020.
28. Hiroshi Kawano, Nobuhito Naito, 安宅 克博, 今倉 健, Yuya Yamashita, 高橋 直希, Mayo Kondou, Seidai Satou, Yuko Toyoda and Yasuhiko Nishioka :
当院における進行性線維化を伴う膠原病関連間質性肺疾患の検討,
第64回日本リウマチ学会総会・学術集会, Aug. 2020.
29. Yuya Yamashita, Hiroshi Kawano, Takeshi Imakura, Nobuhito Naito, Mayo Kondou, Hirokazu Ogino, Seidai Satou, Yuko Toyoda, 後東 久嗣 and Yasuhiko Nishioka :
TAFRO症候群の1例,
第29回日本リウマチ学会中国・四国支部学術集会, Dec. 2018.

Et cetera, Workshop:

1. 山崎 佳那子, 湊 優子, 中島 美世, Mariko Niki, Kazutoshi Murao, Yoshiaki Kubo, 小川 瑛 and Yuya Yamashita :
JAK阻害薬投与中に発症した皮膚クリプトコッカス症の1例,
第121回日本皮膚科学会総会, Jun. 2022.