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徳島大学研究支援・産官学連携センター (researchmapへのインポート用ファイル) [PDF解説] [researchmapへの自動反映について]

研究活動

専門分野

研究テーマ

著書・論文

学術論文(審査論文):

1. Yuji Koriyama, Akihiro Hori, Hisanori Ito, Shuji Yonezawa, Yoshiyasu Baba, Norihiko Tanimoto, Tatsuhiko Ueno, Shiho Yamamoto, Takahiko Yamamoto, Naoya Asada, Kenji Morimoto, Shunsuke Einaru, Katsunori Sakai, Takushi Kanazu, Akihiro Matsuda, Yoshitaka Yamaguchi, Takuya Oguma, Maarten Timmers, Luc Tritsmans, Ken-Ichi Kusakabe, Akira Kato and Gaku Sakaguchi :
Discovery of Atabecestat (JNJ-54861911): A Thiazine-Based β-Amyloid Precursor Protein Cleaving Enzyme 1 Inhibitor Advanced to the Phase 2b/3 EARLY Clinical Trial.,
Journal of Medicinal Chemistry, Vol.64, No.4, 1873-1888, 2021.
(DOI: 10.1021/acs.jmedchem.0c01917,   PubMed: 33588527)
2. Ken-Ichi Kusakabe, Nobuyuki Ide, Yataro Daigo, Takeshi Itoh, Takahiko Yamamoto, Hiroshi Hashizume, Kohei Nozu, Hiroshi Yoshida, Genta Tadano, Sachie Tagashira, Kenichi Higashino, Yousuke Okano, Yuji Sato, Makiko Inoue, Motofumi Iguchi, Takayuki Kanazawa, Yukichi Ishioka, Keiji Dohi, Yasuto Kido, Shingo Sakamoto, Shigeru Ando, Masahiro Maeda, Masayo Higaki, Yoshiyasu Baba and Yusuke Nakamura :
Discovery of imidazo[1,2-b]pyridazine derivatives: selective and orally available Mps1 (TTK) kinase inhibitors exhibiting remarkable antiproliferative activity.,
Journal of Medicinal Chemistry, Vol.58, No.4, 1760-1775, 2015.
(DOI: 10.1021/jm501599u,   PubMed: 25625617)
3. Ken-ichi Kusakabe, Nobuyuki Ide, Yataro Daigo, Yuki Tachibana, Takeshi Itoh, Takahiko Yamamoto, Hiroshi Hashizume, Yoshio Hato, Kenichi Higashino, Yousuke Okano, Yuji Sato, Makiko Inoue, Motofumi Iguchi, Takayuki Kanazawa, Yukichi Ishioka, Keiji Dohi, Yasuto Kido, Shingo Sakamoto, Kazuya Yasuo, Masahiro Maeda, Masayo Higaki, Kazuo Ueda, Hidenori Yoshizawa, Yoshiyasu Baba, Takeshi Shiota, Hitoshi Murai and Yusuke Nakamura :
Indazole-based potent and cell-active Mps1 kinase inhibitors: rational design from pan-kinase inhibitor anthrapyrazolone (SP600125).,
Journal of Medicinal Chemistry, Vol.56, No.11, 4343-4356, 2013.
(DOI: 10.1021/jm4000215,   PubMed: 23634759)
4. Yoshiyasu Baba, Nozomu Hirukawa and Mikiko Sodeoka :
Optically active cantharidin analogues possessing selective inhibitory activity on Ser/Thr protein phosphatase 2B (calcineurin): implications for the binding mode.,
Bioorganic & Medicinal Chemistry, Vol.13, No.17, 5164-5170, 2005.
(DOI: 10.1016/j.bmc.2005.05.013,   PubMed: 15951185)
5. Yoshiyasu Baba, Yosuke Ogoshi, Go Hirai, Takeshi Yanagisawa, Kumiko Nagamatsu, Satoshi Mayumi, Yuichi Hashimoto and Mikiko Sodeoka :
Design, synthesis, and structure-activity relationship of new isobenzofuranone ligands of protein kinase C.,
Bioorganic & Medicinal Chemistry Letters, Vol.14, No.11, 2963-2967, 2004.
(DOI: 10.1016/j.bmcl.2004.02.097,   PubMed: 15125969)

総説・解説:

1. 馬場 良泰 :
BOOKS紹介 製薬会社は生き残れるか,
MEDCHEM NEWS, Vol.31, No.3, 154, 2021年8月.
2. 馬場 良泰 :
BOOKS 紹介 植物はなぜ薬を作るのか,
MEDCHEM NEWS, Vol.30, No.3, 2020年8月.