Tokushima University / Educator and Researcher Directory --- Nunomura, Toshiyuki

Field of Study

Subject of Study

Book / Paper

Academic Paper (Judged Full Paper):

1.	Takuya Takashima, Momoyo Azuma, Masami Sato, Konomi Moriwaki, Saki Saijo, Natsuki Bando, Hiroki Sato, Yuki Nakano, Toshiyuki Nunomura, Manabu Ishihara, Yoshitoyo Ueno, Taiga Itagaki and Jun Oto : Successful treatment of Trichosporon asahii fungemia with isavuconazole in a patient with prominent renal dysfunction and intestinal absorption disorder., Kansenshōgaku Zasshi, 99, 5, 352-356, 2025. (Link to Publication Site) ● Publication site (DOI): 10.11150/kansenshogakuzasshi.e25001 (Link to Search Site for Scientific Articles) ● Search Scopus @ Elsevier (DOI): 10.11150/kansenshogakuzasshi.e25001 (DOI: 10.11150/kansenshogakuzasshi.e25001)
2.	Hiroki Sato, Saki Saijo, Kota Miyoshi, Masaki Terazawa, Shotaro Otani, Konomi Moriwaki, Kazuki Momota, Takuya Takashima, Toshiyuki Nunomura, Manabu Ishihara, Taiga Itagaki and Jun Oto : Successful treatment for collagen vascular disease-related respiratory failure with inhaled nitric oxide as a bridging therapy: A case report, The Journal of Medical Investigation : JMI, 73, 1.2, 270-273, 2025. (Summary) Inhaled nitric oxide (iNO) is approved in Japan for perioperative pulmonary hypertension and persistent pulmonary hypertension in newborns;however, its role in non-cardiac respiratory failure is unclear. A 47-year-old woman with Sjögren's syndrome developed severe acute type I respiratory failure due to collagen vascular disease. Despite high-FIO2 ventilation, her PaO2/FIO2 ratio remained <80, and extracorporeal membrane oxygenation (ECMO) was considered. Administration of iNO at 10 ppm improved oxygenation, with a rapid increase in PaO2/FIO2 ratio. This response allowed time for steroid pulse therapy, rituximab, plasma exchange, and pleural drainage, which stabilized the patient's condition without ECMO. Notably, the temporal association between iNO initiation and rapid oxygenation improvement suggests that pulmonary vascular dysfunction was a major contributor to hypoxemia. Subsequent stabilization with immunosuppressive therapy highlights the role of iNO as a bridging therapy rather than a definitive treatment. In this case, iNO may have served as a bridging therapy, improving oxygenation until immunosuppressive treatment was effective. iNO may serve as a useful interim measure for avoiding ECMO in collagen vascular disease-associated respiratory failure, particularly when pulmonary hypertension is suspected. J. Med. Invest. 73 : 270-273, February, 2026. (Keyword) case report / collagen vascular disease / inhaled nitric oxide / respiratory failure (Link to Publication Site) ● Publication site (DOI): 10.2152/jmi.73.270 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 42021089 ● Summary page in Scopus @ Elsevier: 2-s2.0-105036608181 (DOI: 10.2152/jmi.73.270, PubMed: 42021089, Elsevier: Scopus)
3.	Takuya Takashima, Marina Okubo, Shotaro Otani, Masaki Terazawa, Konomi Moriwaki, Saki Saijo, Natsuki Bando, Kazuki Momota, Hiroki Sato, Yuki Nakano, Toshiyuki Nunomura, Manabu Ishihara, Yoshitoyo Ueno, Taiga Itagaki and Jun Oto : Effect of positive-pressure ventilation before extubation on respiratory function: physiological evaluation under simulated extubation, The Journal of Medical Investigation : JMI, 72, 3, 361-366, 2025. (Summary) Positive-pressure ventilation (PPV) before extubation may improve oxygenation and reduce complications after extubation. However, no study has quantitatively evaluated the effects of extubation on breathing and lung volume. A crossover randomized study was performed on 16 patients who received mechanical ventilation and planned to undergo extubation in the intensive-care unit. We used the automatic tube compensation (ATC) mode to simulate extubation. We used electrical impedance tomography and an esophageal balloon catheter to evaluate the work of breathing and lung volume after simulated extubation. We compared the work of breathing and lung volume with and without PPV before simulated extubation. There were no differences in the changes in end-expiratory lung impedance (-7.4 [-18.2-2.3] vs. -11.2 [-16.6-1.1] arbitrary units, p=0.53), anterior-to-posterior ventilation ratio (0.60 [0.49-0.74] vs. 0.60 [0.52-0.79], p=0.75), esophageal pressure swing (4.9 [2.1-8.7] vs. 5.4 [1.9-6.6] cmH2O, p=0.61), dynamic transpulmonary pressure (7.2 [6.7-9.9] vs. 7.6 [6.6-9.7] cmH2O, p=0.93), and pressure time product (2.4 [1.4-4.2] vs. 3.1 [1.0-4.3] cmH2O*s, p=0.84) with and without PPV before simulated extubation. PPV before extubation did not affect breathing work or lung volume after extubation. Therefore, it may delay extubation and increase patient stress. J. Med. Invest. 72 : 361-366, August, 2025. (Keyword) electrical impedance tomography / extubation / intensive care unit / spontaneous breathing test / transpulmonary pressure (Link to Publication Site) ● Publication site (DOI): 10.2152/jmi.72.361 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 41183938 ● Summary page in Scopus @ Elsevier: 2-s2.0-105020772526 (DOI: 10.2152/jmi.72.361, PubMed: 41183938, Elsevier: Scopus)
4.	Hiroki Sato, Emiko Nakataki, Toshiyuki Nunomura, 村上尚哉, 堀洋二, Jun Oto and Taiga Itagaki : 歯性感染症を契機に発症したPrevotella属によるレミエール症候群の一例．, 第51回日本救急医学会総会・学術集会, 2023.
5.	Yuki Nakano, Yoshitoyo Ueno, Emi Ishitani, Koji Sato, Hiroki Sato, Kazuki Momota, Natsuki Bando, Yusuke Akimoto, Toshiyuki Nunomura, Manabu Ishihara, Natsuki Tane, Taiga Itagaki, Yoshiaki Kitamura and Jun Oto : Repetitive postoperative extubation failure due to dynamic inspiratory airway collapse concomitant with subglottic stenosis in a patient who previously underwent tracheostomy., The Journal of Medical Investigation : JMI, 70, 1.2, 301-305, 2023. (Summary) We should be aware of the history of tracheostomy, especially at high tracheostomy sites, even in the absence of respiratory symptoms as risk factors for dynamic inspiratory airway collapse concomitant with subglottic stenosis contributing to repeated respiratory failure after extubation. J. Med. Invest. 70 : 301-305, February, 2023. (Keyword) Humans / female / Adult / Tracheostomy / Airway Extubation / Constriction, Pathologic / Intubation, Intratracheal / Respiration, Artificial (Tokushima University Institutional Repository) ● Metadata: 2011120 (Link to Publication Site) ● Publication site (DOI): 10.2152/jmi.70.301 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 37164740 ● Summary page in Scopus @ Elsevier: 2-s2.0-85158867166 (Tokushima University Institutional Repository: 2011120, DOI: 10.2152/jmi.70.301, PubMed: 37164740, Elsevier: Scopus)
6.	Yuki Nakano, Koji Sato, Hiroki Sato, Kazuki Momota, Yusuke Akimoto, Toshiyuki Nunomura, Yuta Arai, Manabu Ishihara, Yoshitoyo Ueno, Natsuki Tane, Taiga Itagaki and Jun Oto : 経肺圧を指標としたPEEP設定により，致死的低酸素血症から改善した神経芽細胞腫に伴う腹部コンパートメント症候群の一乳児症例, Shikoku Acta Medica, 2022;78, 3,4, 115-120, 2022. (Summary) Background : Neuroblastoma is the most common extracranial solid tumor of childhood. Although the prognosis of neuroblastoma is relatively good, newborns less than two months of age with stage 4S neuroblastoma may present with aggressive hypoxia and restrictive respiratory impairment due to abdominal compartment syndrome. Case presentation : Two-month-old girl, height of 63 cm and body weight of 10 kg. She was diagnosed as neuroblastoma with Stage 4S. Because she was suffered from refractory hypoxemia and restrictive respiratory impairment due to abdominal compartment syndrome induced by multiple liver metastasis and massive ascites, she was transferred to our ICU. Her trachea was intubated and ventilated with assist/controlled mode, driving pressure 22 cmH2O, positive end-expiratory pressure(PEEP)8 cmH2O, fraction of inspiratory oxygen(FIO2)1.0, but tidal volume was obtained only 3.2 mL/kg and PaO2/FIO2 ratio of 55 mmHg. Therefore, we insert esophageal sensor and monitored esophageal pressure to performed transpulmonary pressure guided PEEP titration. When we changed PEEP from 8 to 15 cmH2O so that the end-expiratory transpulmonary pressure achieving 0 to 5 cmH2O, her oxygenation(PaO2/FIO2 ratio : 55 to 178 mmHg)and respiratory compliance(1.4 to 3.0 mL/cmH2O)were dramatically improved. Her respiratory condition was further stabilized by ascites puncture and radiotherapy, and the patient was extubated successfully on the 25th ICU day. Conclusions : Although pediatric neuroblastoma with stage 4S may induce severe respiratory efficiency, the responsiveness of treatment for neuroblastoma is promising. Multimodal treatments including optimal ventilator management such as transpulmonary pressure -guided PEEP titration contributes to improved patient's prognosis. (Keyword) Neuroblastoma / Abdominal compartment syndrome / Transpulmonary pressure (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1050867133848820608 (CiNii: 1050867133848820608)
7.	Yoshitoyo Ueno, Saki Harada, Koji Sato, Kazuki Momota, Hiroki Sato, Yusuke Akimoto, Yuta Arai, Toshiyuki Nunomura, Manabu Ishihara, Natsuki Tane, Taiga Itagaki, Yasuhiko Nishioka and Jun Oto : Independent lung ventilation for the management of acute allograft rejection after single-lung transplantation for end-stage emphysema., The Journal of Medical Investigation : JMI, 69, 3.4, 323-327, 2022. (Summary) Background : We herein report the use of independent lung ventilation (ILV) for managing acute allograft rejection after single-lung transplantation (SLT) for end-stage emphysema. Case presentation : A 54-year-old woman was transferred to our hospital with severe hypoxemia and respiratory distress due to unilateral lung disease with diffuse alveolar damage in the right donor lung associated with acute allograft rejection and with hyperinflation of the left native lung due to emphysema. She was unresponsive to immunosuppressive medications and conventional ventilation strategies, so different ventilator settings for each lung were required. A double-lumen endotracheal tube (DLT) was inserted, and ILV was initiated. The right lung was ventilated with high positive end-expiratory pressure (PEEP), intended for lung recruitment, and the left lung was ventilated with lung protective strategies using a low tidal volume and low levels of PEEP to avoid hyperinflation. Two days later, her lung function was dramatically improved, and the DLT was replaced with a single-lumen endotracheal tube. Gas exchange was maintained, and she was successfully weaned from mechanical ventilation on intensive-care unit day 15. Conclusions : ILV appears to be effective and safe for managing acute allograft rejection after SLT for emphysema. J. Med. Invest. 69 : 323-327, August, 2022. (Keyword) Allografts / Emphysema / Female / Humans / Lung / Lung Transplantation / Middle Aged / Pulmonary Emphysema / Respiration, Artificial (Link to Publication Site) ● Publication site (DOI): 10.2152/jmi.69.323 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 36244790 ● Search Scopus @ Elsevier (PMID): 36244790 ● Search Scopus @ Elsevier (DOI): 10.2152/jmi.69.323 (DOI: 10.2152/jmi.69.323, PubMed: 36244790)
8.	Yusuke Akimoto, Natsuki Bando, Hiroki Sato, Koji Sato, Kazuki Momota, Toshiyuki Nunomura, Yoshitoyo Ueno, Manabu Ishihara, Natsuki Tane, Taiga Itagaki and Jun Oto : Acquired laryngomalacia as a cause of post-extubation respiratory failure in patient with postoperative seizure and central pontine myelinolysis after craniotomy., The Journal of Medical Investigation : JMI, 69, 3.4, 316-319, 2022. (Summary) Background : Laryngomalacia is a congenital abnormality of the larynx that commonly occurs in children and rarely in adults. We report the first case of acquired laryngomalacia mainly due to postoperative seizure and central pontine myelinolysis after scheduled craniotomy. Case presentation : A 69-year-old man was admitted to the hospital for elective craniotomy for craniopharyngioma. After the surgery, he developed refractory seizure and required intubation and mechanical ventilation in the intensive-care unit (ICU). After treatment for the seizure, he was extubated. However, immediately after extubation, he developed stridor and respiratory retraction. We performed fiberoptic laryngoscopy and confirmed that the epiglottis had collapsed into the posterior wall of the pharynx during inspiration, which was suspected to be laryngomalacia. He received invasive mechanical ventilation for two days following re-extubation. After the second extubation, he developed stridor again due to acquired laryngomalacia. Six days later, his respiratory condition had worsened, and he received re-intubation and tracheostomy. After ICU discharge, central pontine myelinolysis was diagnosed by magnetic resonance imaging. Conclusions : Adult-onset laryngomalacia is a rare cause of upper airway obstruction but should be considered as a cause of postoperative extubation failure. We should not delay performing fiberoptic laryngoscopy to evaluate this pathology and provide optimal treatment. J. Med. Invest. 69 : 316-319, August, 2022. (Keyword) Aged / Airway Extubation / Child / Craniotomy / Humans / Laryngomalacia / Laryngoscopy / Male / Myelinolysis, Central Pontine / Respiratory Insufficiency / Respiratory Sounds / Seizures (Link to Publication Site) ● Publication site (DOI): 10.2152/jmi.69.316 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 36244788 ● CiNii @ National Institute of Informatics (CRID): 1390856738295204480 ● Search Scopus @ Elsevier (PMID): 36244788 ● Search Scopus @ Elsevier (DOI): 10.2152/jmi.69.316 (DOI: 10.2152/jmi.69.316, PubMed: 36244788, CiNii: 1390856738295204480)
9.	Yoshitoyo Ueno, Koji Sato, Kazuki Momota, Hiroki Sato, Yuki Nakano, Yusuke Akimoto, Toshiyuki Nunomura, Natsuki Tane, Taiga Itagaki and Jun Oto : The quality and quantity of sleep on dexmedetomidine during high-flow nasal cannula oxygen therapy in critically ill patients., The Journal of Medical Investigation : JMI, 69, 3.4, 266-272, 2022. (Summary) Purpose : High-flow nasal cannula oxygen therapy (HFNC) is a new type of non-invasive respiratory support for acute respiratory failure patients. However, patients receiving HFNC often develop sleep disturbances. We therefore examined whether dexmedetomidine could preserve the sleep characteristics in patients who underwent HFNC. Patients and Methods : This was a pilot, randomized controlled study. We assigned critically ill patients treated with HFNC to receive dexmedetomidine (0.2 to 0.7 µg / kg / h, DEX group) or not (non-DEX group) at night (9:00 p.m. to 6:00 a.m.). Polysomnograms were monitored during the study period. The primary outcomes were total sleep time (TST), sleep efficiency and duration of stage 2 non-rapid eye movement (stage N2) sleep. Results : Of the 28 patients who underwent randomization, 24 were included in the final analysis (12 patients per group). Dexmedetomidine increased the TST (369 min vs. 119 min, p = 0.024) and sleep efficiency (68% vs. 22%, P = 0.024). The duration of stage N2 was increased in the DEX group compared with the non-DEX group, but this finding did not reach statistical significance. The incidences of respiratory depression and hemodynamic instability were similar between the two groups. Conclusions : In critically ill patients who underwent HFNC, dexmedetomidine may optimize the sleep quantity without any adverse events. J. Med. Invest. 69 : 266-272, August, 2022. (Keyword) Cannula / Critical Illness / Dexmedetomidine / Humans / Oxygen / Sleep (Tokushima University Institutional Repository) ● Metadata: 2008910 (Link to Publication Site) ● Publication site (DOI): 10.2152/jmi.69.266 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 36244779 ● CiNii @ National Institute of Informatics (CRID): 1390293788341782528 ● Search Scopus @ Elsevier (PMID): 36244779 ● Search Scopus @ Elsevier (DOI): 10.2152/jmi.69.266 (Tokushima University Institutional Repository: 2008910, DOI: 10.2152/jmi.69.266, PubMed: 36244779, CiNii: 1390293788341782528)
10.	Taiga Itagaki, Nobuto Nakanishi, Takuya Takashima, Yoshitoyo Ueno, Natsuki Tane, Yumiko Tsunano, Toshiyuki Nunomura and Jun Oto : Effect of controlled ventilation during assist-control ventilation on diaphragm thickness : a post hoc analysis of an observational study., The Journal of Medical Investigation : JMI, 67, 3.4, 332-337, 2020. (Summary) Background : Since diaphragm passivity induces oxidative stress that leads to rapid atrophy of diaphragm, we investigated the effect of controlled ventilation on diaphragm thickness during assist-control ventilation (ACV). Methods : Previously, we measured end-expiratory diaphragm thickness (Tdiee) of patients mechanically ventilated for more than 48 hours on days 1, 3, 5 and 7 after the start of ventilation. We retrospectively investigated the proportion of controlled ventilation during the initial 48-hour ACV (CV48%). Patients were classified according to CV48% : Low group, less than 25% ; High group, higher than 25%. Results : Of 56 patients under pressure-control ACV, Tdiee increased more than 10% in 6 patients (11%), unchanged in 8 patients (14%) and decreased more than 10% in 42 patients (75%). During the first week of ventilation, Tdiee decreased in both groups : Low (difference, -7.4% ; 95% confidence interval [CI], -10.1% to -4.6% ; p < 0.001) and High group (difference, -5.2% ; 95% CI, -8.5% to -2.0% ; p = 0.049). Maximum Tdiee variation from baseline did not differ between Low (-15.8% ; interquartile range [IQR], -22.3 to -1.5) and High group (-16.7% ; IQR, -22.6 to -11.1, p = 0.676). Conclusions : During ACV, maximum variation in Tdiee was not associated with proportion of controlled ventilation higher than 25%. J. Med. Invest. 67 : 332-337, August, 2020. (Tokushima University Institutional Repository) ● Metadata: 2008366 (Link to Publication Site) ● Publication site (DOI): 10.2152/jmi.67.332 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 33148911 ● Summary page in Scopus @ Elsevier: 2-s2.0-85095587008 (Tokushima University Institutional Repository: 2008366, DOI: 10.2152/jmi.67.332, PubMed: 33148911, Elsevier: Scopus)

Proceeding of Domestic Conference:

1.	Takuya Takashima, Taiga Itagaki, Shotaro Otani, Yusuke Akimoto, Masaki Terazawa, Saki Saijo, Hiroki Sato, Kazuki Momota, Toshiyuki Nunomura and Jun Oto : 経横隔膜圧を指標に吸気圧を調整した人工呼吸器離脱困難の一症例．, Mar. 2026.
2.	Saki Saijo, Kota Miyoshi, Masaki Terazawa, Shotaro Otani, 森脇好乃美, Kazuki Momota, Hiroki Sato, Takuya Takashima, Toshiyuki Nunomura and Jun Oto : 急性心筋梗塞後の重症僧帽弁閉鎖不全に対し ECMO 戦略と MitraClip で救命し得た一例．, Mar. 2026.
3.	Shotaro Otani, Kota Miyoshi, Masaki Terazawa, 森脇好乃美, Saki Saijo, Kazuki Momota, Hiroki Sato, Toshiyuki Nunomura, Takuya Takashima and Jun Oto : 低用量リスペリドン投与後に悪性症候群を発症した集中治療患者の一例．, Mar. 2026.
4.	Toshiyuki Nunomura, Emiko Nakataki, Hiroki Sato, 堀祥昌, 宮本綾香, 小路美咲, 池崎尚子, Taiga Itagaki and Jun Oto : 徳島総合メディカルゾーンにおける ICU 間連携と転院搬送の検討．, Mar. 2026.
5.	Masaki Terazawa, Kota Miyoshi, Shotaro Otani, Saki Saijo, 森脇好乃美, Kazuki Momota, Hiroki Sato, Takuya Takashima, Toshiyuki Nunomura and Jun Oto : 劇症型心筋炎にメンデルソン症候群を合併し段階的 ECMO 戦略と IMPELLA 併用で救命し得た一例．, Mar. 2026.
6.	Hiroki Sato, Emiko Nakataki, 堀祥昌, 小路美咲, 宮本綾香, Saki Saijo, Toshiyuki Nunomura, Taiga Itagaki and Jun Oto : 心肺停止蘇生後患者における NSE 測定の運用実態と今後の課題．, Mar. 2026.
7.	Yuki Nakano, Shotaro Otani, Masaki Terazawa, 森脇好乃美, Saki Saijo, Takuya Takashima, Toshiyuki Nunomura, Manabu Ishihara, Taiga Itagaki and Jun Oto : 前縦隔腫瘍による気道緊急に対して VV-ECMO と化学療法を併用し救命した妊婦症例．, Mar. 2026.
8.	堀祥昌, Emiko Nakataki, Hiroki Sato, 小路美咲, 宮本綾香, Toshiyuki Nunomura, 池﨑尚子 and Taiga Itagaki : ICU における Midline カテーテル使用経験 ―26 例の後方視的検討と代表症例提示―．, Mar. 2026.
9.	Takuya Takashima, 大久保まりな, Saki Saijo, Natsuki Bando, Kazuki Momota, Hiroki Sato, Toshiyuki Nunomura, Manabu Ishihara and Jun Oto : 【集中治療甲子園】抜管前の陽圧換気が呼吸機能に与える影響の生理学的評価．, Mar. 2026.
10.	Toshiyuki Nunomura : シンポジスト「シンポジウム:DICにおける治療介入，薬剤選択のポイント(症例をもとに)」, Nov. 2025.
11.	Takuya Takashima, Saki Saijo, Kazuki Momota, Hiroki Sato, Toshiyuki Nunomura, Manabu Ishihara, Yoshitoyo Ueno and Jun Oto : CRRTでの透析導入にも関わらず不均衡症候群により重篤な意識障害を呈した1例．, Oct. 2025.
12.	Takuya Takashima, Kota Miyoshi, Masaki Terazawa, Shotaro Otani, 森脇好乃美, Saki Saijo, Kazuki Momota, Hiroki Sato, Toshiyuki Nunomura and Jun Oto : ACTH療法中に縦隔膿瘍と頚椎硬膜外膿瘍を発症し速やかに外科的介入を行えた1例．, Jul. 2025.
13.	Toshiyuki Nunomura, Emiko Nakataki, Hiroki Sato, Kazuki Momota, 宮本綾香, Taiga Itagaki and Jun Oto : 徳島県総合メディカルゾーンにおけるMCS upgrade に関する検討．, Jul. 2025.
14.	Kazuki Momota, 森脇好乃美, Hiroki Sato, Saki Saijo, Takuya Takashima, Toshiyuki Nunomura, Yoshitoyo Ueno, Taiga Itagaki and Jun Oto : 転倒を契機に出血性ショックを呈したEhlers-Danlos syndrome の一例．, Jul. 2025.
15.	中村悠亮, 林昌晃, 近田優介, Toshiyuki Nunomura, Jun Oto and 森西啓介 : VA -ECMO 管理中に上肢酸素飽和度低下を認めVAV- ECMO 移行した一例．, Jul. 2025.
16.	宮本綾香, Emiko Nakataki, 小路美咲, 堀祥昌, 池崎尚子, Toshiyuki Nunomura, Hiroki Sato and Taiga Itagaki : 当院のRRS 改編前後における予期せぬ心停止及び死亡の調査．, Jul. 2025.
17.	Hiroki Sato, Emiko Nakataki, 堀祥昌, 小路美咲, 宮本綾香, Saki Saijo, Toshiyuki Nunomura, Taiga Itagaki and Jun Oto : 壊死性肺炎と鑑別を要する肺梗塞に対して抗菌薬使用なく経過した症例．, Jul. 2025.
18.	Shotaro Otani, Jun Oto, Taiga Itagaki, Takuya Takashima, Yoshitoyo Ueno, Toshiyuki Nunomura, Hiroki Sato, Kazuki Momota, Saki Saijo and Ryota Matsumoto : 胸腹部大動脈人工血管置換術後ICU管理中に，脊髄虚血による両下肢麻痺を生じた一例．, Jul. 2025.
19.	Saki Saijo, Takuya Takashima, Toshiyuki Nunomura, Yoshitoyo Ueno, Manabu Ishihara, Jun Oto, 森脇好乃美, Kazuki Momota and Hiroki Sato : 一酸化窒素吸入療法によりECMO導入を回避し得た一例．, Jul. 2025.
20.	久次米里衣, Emiko Nakataki, 鈴江正基, Toshiyuki Nunomura and 川村圭司 : 多職種カンファレンスを通じて目標を共有し，ADL に汎化できた一例．, Jul. 2025.
21.	Takuya Takashima, 大久保茉里奈, Saki Saijo, Natsuki Bando, Kazuki Momota, Hiroki Sato, Toshiyuki Nunomura, Manabu Ishihara, Yoshitoyo Ueno and Jun Oto : 優秀演題セッション「抜管前の陽圧換気が呼吸機能に与える影響の生理学的評価」, Jul. 2025.
22.	北別府孝輔, Toshiyuki Nunomura, 三橋乙矢, 沖圭祐, 筑後桃子, 辻中海斗 and 西本直也 : シンポジウム4:学術集会でそこまでするの!?リアルカンファレンスのその後 ∼臨床で変化はあったのか∼, Jul. 2025.
23.	Toshiyuki Nunomura : 司会「シンポジウム2:循環管理の最前線」, 日本集中治療医学会第9回中国・四国支部学術集会, Jul. 2025.
24.	Yuta Arai, Takuya Takashima, Kazuki Momota, Saki Saijo, Hiroki Sato, Toshiyuki Nunomura, Yoshitoyo Ueno, Manabu Ishihara, Masafumi Harada and Jun Oto : 人工呼吸中の気道出血に対して気管支動脈塞栓術が有用であった2例, 日本集中治療医学会第9回中国・四国支部学術集会, Jul. 2025.
25.	池崎尚子, Hiroki Sato, 宮本綾香, Toshiyuki Nunomura, Emiko Nakataki and Taiga Itagaki : 当院ICUにおけるOpen Abdominal Managementの検討．, 第52回日本集中治療医学会学術集会(3月14∼16日，福岡市), Mar. 2025.
26.	Emiko Nakataki, Toshiyuki Nunomura, Hiroki Sato, 宮本綾香, 池崎尚子 and Taiga Itagaki : 重症の急性低酸素性呼吸不全患者に対する意思決定支援:TLTと緩和的抜管提案の取り組み．, 第52回日本集中治療医学会学術集会(3月14∼16日，福岡市), Mar. 2025.
27.	Toshiyuki Nunomura, Emiko Nakataki, Hiroki Sato, 宮本綾香, 池崎尚子 and Taiga Itagaki : 院外心停止患者に対する倫理的方針決定と緩和的抜管のプロセス．, 第52回日本集中治療医学会学術集会(3月14∼16日，福岡市), Mar. 2025.
28.	Emiko Nakataki, Toshiyuki Nunomura, Hiroki Sato, 宮本綾香, 池崎尚子 and Taiga Itagaki : パネルディスカッション30(PD) / 人工呼吸器をwithdrawするとき∼意思決定から抜管まで，各施設での取り組み∼．「期間を限定した挿管下人工呼吸管理」と「緩和的抜管」の提案が重症の急性呼吸不全患者にもたらしたもの．, 第52回日本集中治療医学会学術集会(3月14∼16日，福岡市), Mar. 2025.
29.	Manabu Ishihara, Masaaki Korai, Natsuki Bando, Yoshitoyo Ueno, Takuya Takashima, Toshiyuki Nunomura, Kenji Shimada, Yasushi Takagi and Jun Oto : シンポジウム27(SY) / くも膜下出血の新たな管理:先端治療の恩恵と注意点．くも膜下出血に対するクラゾセンタンの使用と合併症，自施設でプロトコール作成前後の比較．, 第52回日本集中治療医学会学術集会(3月14∼16日，福岡市), Mar. 2025.
30.	Saki Saijo, Kazuki Momota, Hiroki Sato, Takuya Takashima, Toshiyuki Nunomura, Yoshitoyo Ueno, Manabu Ishihara and Jun Oto : 巨大胸腺腫摘出術後に人工呼吸器離脱の判断に苦慮した一例．, 第4回徳島外科医会(2月15日，徳島市), Feb. 2025.
31.	Yuki Nakano, Saki Saijo, Natsuki Bando, Hiroki Sato, Kazuki Momota, Takuya Takashima, Toshiyuki Nunomura, Yoshitoyo Ueno, Manabu Ishihara, Taiga Itagaki and Jun Oto : オルニチントランスカルバミラーゼ欠損症による難治性高アンモニア血症に対し集学的治療で神経学的後遺症なく救命できた小児症例．, 第52回日本救急医学会総会・学術集会(10月13∼15日，仙台市), Oct. 2024.
32.	Manabu Ishihara, Saki Saijo, Natsuki Bando, Kazuki Momota, Hiroki Sato, Yuki Nakano, Takuya Takashima, Toshiyuki Nunomura, Yoshitoyo Ueno, Taiga Itagaki and Jun Oto : くも膜下出血治療の現状と課題:救急科・脳神経外科のダブルボード専門医が行う神経集中治療．, 第52回日本救急医学会総会・学術集会(10月13∼15日，仙台市), Oct. 2024.
33.	鈴江正基, Emiko Nakataki, Toshiyuki Nunomura, 福島翔太, 久次米里衣, 殿谷淳子, 寺田透, 石田直己 and 津川武弘 : 長期人工呼吸器装着症例に対して，呼吸ケアサポートチームの介入が有効であった1例．, 日本集中治療医学会第8回中国・四国支部学術集会(6月15∼16日，広島市), Jun. 2024.
34.	福島翔太, Emiko Nakataki, Toshiyuki Nunomura, 檜田柊吾, 鈴江正基 and 津川武弘 : 人工呼吸管理を要したダウン症候群患者に対し，患者背景を考慮したゴール設定が行えた一例．, 日本集中治療医学会第8回中国・四国支部学術集会(6月15∼16日，広島市), Jun. 2024.
35.	久次米里衣, Emiko Nakataki, Toshiyuki Nunomura, 鈴江正基, 福島翔太 and 津川武弘 : ．2回のICU入室を経てPICSを発症したが，PICS評価指標改善とリハビリテーション意欲上昇を得られた1例．, 日本集中治療医学会第8回中国・四国支部学術集会(6月15∼16日，広島市), Jun. 2024.
36.	Emiko Nakataki, Toshiyuki Nunomura, Hiroki Sato, 松田和徳, 岡部寛, 山本綾香, 堀洋二, 瀬渡洋道 and Taiga Itagaki : A群溶血性レンサ球菌による頸部軟部組織感染症から下顎部の壊死をきたした一例．, 日本集中治療医学会第8回中国・四国支部学術集会(6月15∼16日，広島市), Jun. 2024.
37.	Takuya Takashima, Momoyo Azuma, Saki Saijo, Natsuki Bando, Yuki Nakano, Toshiyuki Nunomura, Manabu Ishihara, Yoshitoyo Ueno, Taiga Itagaki and Jun Oto : 腎機能障害を有する深在性トリコスポロン症患者に対するイサブコナゾールでの治療経験．, 日本集中治療医学会第8回中国・四国支部学術集会(6月15∼16日，広島市), Jun. 2024.
38.	Toshiyuki Nunomura : 布村俊幸．シンポジスト「シンポジウム:DIC診療における疑問点」, 第3回南四国・集中治療医学シンポジウム, Nov. 2023.
39.	Emiko Nakataki, Toshiyuki Nunomura, Hiroki Sato, Taiga Itagaki and 松本大資 : Time limited trialが有効であった若年難治性気胸の一例．, 第45回日本呼吸療法医学会学術集会, Aug. 2023.
40.	福島翔太, Emiko Nakataki, Toshiyuki Nunomura, Hiroki Sato, 川人美鈴, 殿谷淳子, 坂東加奈子 and 津川武弘 : 当院独自の早期離床プロトコルが侵襲的人工呼吸管理症例の退院時日常生活動作レベルに及ぼす影響．, 日本集中治療医学会第7回中国・四国支部学術集会, Jul. 2023.
41.	Koji Sato, Yoshitoyo Ueno, Natsuki Bando, Kazuki Momota, Takuya Takashima, Hiroki Sato, Toshiyuki Nunomura, Manabu Ishihara, Taiga Itagaki and Jun Oto : ステロイドパルス療法後にオルニチントランスカルバミラーゼ欠損症による高アンモニア脳症を発症した1例．, 日本集中治療医学会第7回中国・四国支部学術集会, Jul. 2023.
42.	Hiroki Sato, Emiko Nakataki, Toshiyuki Nunomura, 藤本稜, 川下陽一郎, 山村里恵, Taiga Itagaki and Jun Oto : カルバマゼピンによる薬剤性再生不良性貧血と薬疹から不良な転帰を辿った一症例．, 日本集中治療医学会第7回中国・四国支部学術集会, Jul. 2023.
43.	池崎尚子, Emiko Nakataki, 荒川悠祐, Toshiyuki Nunomura, Hiroki Sato and 曽我朋宏 : 食道裂孔ヘルニア嚢内で発生した結腸穿通に対する手術中に気胸を生じた1症例．, 日本集中治療医学会第7回中国・四国支部学術集会, Jul. 2023.
44.	Toshiyuki Nunomura : 児童虐待が疑われた小児搬送症例．, 令和5年度第1回事後検証症例発表会, Jul. 2023.
45.	Natsuki Bando, Kazuki Momota, Koji Sato, Hiroki Sato, Yusuke Akimoto, Toshiyuki Nunomura, Manabu Ishihara, Yoshitoyo Ueno, Natsuki Tane, Taiga Itagaki and Jun Oto : セツキシマブ投与後のインフュージョンリアクションから心停止に至るも後遺症なく救命できた一症例．, 第39回日本救急医学会中国四国地方会, Jul. 2023.
46.	Koji Sato, Yoshitoyo Ueno, Natsuki Bando, Kazuki Momota, Takuya Takashima, Hiroki Sato, Toshiyuki Nunomura, Manabu Ishihara, Natsuki Tane, Taiga Itagaki and Jun Oto : HELLP症候群に伴う急性肝不全，DICに対して血漿交換療法が効果的であった一症例．, 第39回日本救急医学会中国四国地方会, Jul. 2023.
47.	Hiroki Sato, Emiko Nakataki, Toshiyuki Nunomura, 島谷佳光, Taiga Itagaki and Jun Oto : 原因不明の無菌性髄膜炎を契機に痙攣重積状態に進行し不良な転帰を辿った一症例, 第51回日本集中治療医学会学術集会, Mar. 2023.
48.	Natsuki Bando, Koji Sato, Hiroki Sato, Natsuki Bando, Koji Sato, Toshiyuki Nunomura, Yuki Nakano, Takuya Takashima, Manabu Ishihara, Yoshitoyo Ueno, Taiga Itagaki and Jun Oto : 動脈瘤性くも膜下出血へのクラゾセンタン投与により抜管後喉頭浮腫を来した2症例, 第51回日本集中治療医学会学術集会, Mar. 2023.
49.	Yoshitoyo Ueno, 西條早希, 河原良美, Natsuki Bando, Koji Sato, Hiroki Sato, Takuya Takashima, Toshiyuki Nunomura, Manabu Ishihara, Taiga Itagaki and Jun Oto : 自発呼吸トライアル中のHFVIモニタリングに関する検討, 第51回日本集中治療医学会学術集会, Mar. 2023.
50.	福島翔太, 中瀧恵実子, 久次米里衣, Toshiyuki Nunomura, Yuta Arai, 殿谷淳子, 川人美鈴, 坂東加奈子 and 津川武弘 : 当院独自の早期離床プロトコルが侵襲的人工呼吸管理症例の早期離床に及ぼす影響:過去起点コホート研究．, 第50回日本集中治療医学会学術集会, Mar. 2023.
51.	Kazuki Momota, Natsuki Bando, Koji Sato, Hiroki Sato, Yusuke Akimoto, Toshiyuki Nunomura, Yoshitoyo Ueno, Natsuki Tane, Taiga Itagaki and Jun Oto : 非侵襲的陽圧換気中に縦隔気腫を来したCOVID-19肺炎の一症例．, 第50回日本集中治療医学会学術集会, Mar. 2023.
52.	Yuki Nakano, Koji Sato, Hiroki Sato, Kazuki Momota, Yusuke Akimoto, Toshiyuki Nunomura, Yoshitoyo Ueno, Natsuki Tane, Taiga Itagaki and Jun Oto : 気管切開後25年間無症候性に経過した声門下狭窄が気管挿管を機に増悪し，術後抜管困難となった一症例, 第50回日本集中治療医学会学術集会, Mar. 2023.
53.	Yoshitoyo Ueno, Kazuki Momota, Koji Sato, Hiroki Sato, Yusuke Akimoto, Toshiyuki Nunomura, Manabu Ishihara, Natsuki Tane, Taiga Itagaki and Jun Oto : 末期肺気腫に対する片肺移植後の急性拒絶反応に対し，分離肺換気が奏功した一症例, 第50回日本集中治療医学会学術集会, Mar. 2023.
54.	Toshiyuki Nunomura, 中瀧恵実子, Yuta Arai and Taiga Itagaki : COVID-19 に伴う全身性毛細血管漏出症候群により心肺停止に至った一例．, 第50回日本集中治療医学会学術集会, Mar. 2023.
55.	Yoshitoyo Ueno, Hiroki Sato, Kazuki Momota, Koji Sato, Yusuke Akimoto, Toshiyuki Nunomura, Manabu Ishihara, Natsuki Tane, Taiga Itagaki and Jun Oto : 開心術後患者における乳酸値ピークアウトまでの時間と術後経過との関連, 第50回日本集中治療医学会学術集会, Mar. 2023.
56.	Koji Sato, Yoshitoyo Ueno, Hiroki Sato, Kazuki Momota, Yusuke Akimoto, Toshiyuki Nunomura, Manabu Ishihara, Natsuki Tane, Taiga Itagaki and Jun Oto : VA-ECMO, 第50回日本集中治療医学会学術集会, Mar. 2023.
57.	Yuki Nakano, Koji Sato, Hiroki Sato, Kazuki Momota, Yusuke Akimoto, Toshiyuki Nunomura, Yoshitoyo Ueno, Natsuki Tane, Taiga Itagaki and Jun Oto : 高位気管切開既往患者に生じた声門下狭窄および気管軟化症により術後抜管困難となった一症例, 第6回徳島外科学会, Feb. 2023.
58.	Natsuki Bando, 宮本憲哉, Kazuki Momota, Koji Sato, Hiroki Sato, Yusuke Akimoto, Toshiyuki Nunomura, Manabu Ishihara, Yoshitoyo Ueno, Natsuki Tane, Taiga Itagaki and Jun Oto : セツキシマブ投与後のインフュージョンリアクションから心停止に至るも後遺症なく救命できた一症例, 第6回徳島外科学会, Feb. 2023.
59.	Toshiyuki Nunomura : シンポジスト「シンポジウム．DIC の治療意義について」, 第2回南四国・集中治療医学シンポジウム, Nov. 2022.
60.	Kazuki Momota, Natsuki Bando, Koji Sato, Hiroki Sato, Yusuke Akimoto, Toshiyuki Nunomura, Manabu Ishihara, Yoshitoyo Ueno, Natsuki Tane, Taiga Itagaki and Jun Oto : 重篤な循環不全を呈した重症レジオネラ肺炎に対しVA-ECMO導入により救命した1例．, 第50回日本救急医学会総会・学術集会, Oct. 2022.
61.	荒瀬美晴, 大村健史, 井川浩一, Yuta Arai, Toshiyuki Nunomura, Natsuki Tane, 中瀧恵実子, 三村誠二 and Jun Oto : COVID-19患者におけるエアロゾルの発生を最小限に抑える経皮的気管切開術の工夫．, 第49回日本救急医学会総会・学術集会, Nov. 2021.
62.	Toshiyuki Nunomura, Taiga Itagaki, Yuta Arai, 中瀧恵実子 and Jun Oto : 集中治療室内での患者-人工呼吸器非同調に対する意識調査．, 第1回南四国・集中治療医学フォーラム, Nov. 2021.

Designated Assistant Professor : Nunomura, Toshiyuki

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Proceeding of Domestic Conference: