徳島大学 / 教育研究者総覧 --- 秋本雄祐

専門分野

研究テーマ

著書・論文

著書:

1.	秋本雄祐, 大藤純 : 血液浄化療法, 克誠堂出版株式会社, 2022年. (キーワード) ISBN 978-4-7719-0571-9

学術論文(審査論文):

1.	Taiga Itagaki, Yusuke Akimoto, Takuya Takashima and Jun Oto : Ultrasonographic assessment of the diaphragm, Diagnostics, 14, 14, 1481, 2024. (出版サイトへのリンク) ● Publication site (DOI): 10.3390/diagnostics14141481 (文献検索サイトへのリンク) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 39061618 ● CiNii @ 国立情報学研究所 (CRID): 1873118016365469568 ● Summary page in Scopus @ Elsevier: 2-s2.0-85199628772 (DOI: 10.3390/diagnostics14141481, PubMed: 39061618, CiNii: 1873118016365469568, Elsevier: Scopus)
2.	Yusuke Akimoto, Taiga Itagaki, Keisuke Morinishi, Yusuke Chikata and Jun Oto : A bench evaluation of ineffective efforts related to the use of leak compensation algorithm during pressure support ventilation., American Association for Respiratory Care Congress 2023, 2023.
3.	Keisuke Morinishi, Taiga Itagaki, Yusuke Akimoto, Yusuke Chikata and Jun Oto : Effects of novel trigger algorithms on trigger performance and patient-ventilator synchrony: a lung model study. (Editors Choice Session), American Association for Respiratory Care Congress 2023, 2023.
4.	Yuki Nakano, Yoshitoyo Ueno, Emi Ishitani, Koji Sato, Hiroki Sato, Kazuki Momota, Natsuki Bando, Yusuke Akimoto, Toshiyuki Nunomura, Manabu Ishihara, Natsuki Tane, Taiga Itagaki, Yoshiaki Kitamura and Jun Oto : Repetitive postoperative extubation failure due to dynamic inspiratory airway collapse concomitant with subglottic stenosis in a patient who previously underwent tracheostomy., The Journal of Medical Investigation : JMI, 70, 1.2, 301-305, 2023. (要約) We should be aware of the history of tracheostomy, especially at high tracheostomy sites, even in the absence of respiratory symptoms as risk factors for dynamic inspiratory airway collapse concomitant with subglottic stenosis contributing to repeated respiratory failure after extubation. J. Med. Invest. 70 : 301-305, February, 2023. (キーワード) Humans / 女性 (female) / Adult / Tracheostomy / Airway Extubation / Constriction, Pathologic / Intubation, Intratracheal / Respiration, Artificial (徳島大学機関リポジトリ) ● Metadata: 2011120 (出版サイトへのリンク) ● Publication site (DOI): 10.2152/jmi.70.301 (文献検索サイトへのリンク) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 37164740 ● Summary page in Scopus @ Elsevier: 2-s2.0-85158867166 (徳島大学機関リポジトリ: 2011120, DOI: 10.2152/jmi.70.301, PubMed: 37164740, Elsevier: Scopus)
5.	中野勇希, 佐藤功志, 佐藤裕紀, 百田和貴, 秋本雄祐, 布村俊幸, 新井悠太, 石原学, 上野義豊, 田根なつ紀, 板垣大雅, 大藤純 : 経肺圧を指標としたPEEP設定により，致死的低酸素血症から改善した神経芽細胞腫に伴う腹部コンパートメント症候群の一乳児症例, 四国医学雑誌, 2022;78, 3,4, 115-120, 2022年. (要約) Background : Neuroblastoma is the most common extracranial solid tumor of childhood. Although the prognosis of neuroblastoma is relatively good, newborns less than two months of age with stage 4S neuroblastoma may present with aggressive hypoxia and restrictive respiratory impairment due to abdominal compartment syndrome. Case presentation : Two-month-old girl, height of 63 cm and body weight of 10 kg. She was diagnosed as neuroblastoma with Stage 4S. Because she was suffered from refractory hypoxemia and restrictive respiratory impairment due to abdominal compartment syndrome induced by multiple liver metastasis and massive ascites, she was transferred to our ICU. Her trachea was intubated and ventilated with assist/controlled mode, driving pressure 22 cmH2O, positive end-expiratory pressure(PEEP)8 cmH2O, fraction of inspiratory oxygen(FIO2)1.0, but tidal volume was obtained only 3.2 mL/kg and PaO2/FIO2 ratio of 55 mmHg. Therefore, we insert esophageal sensor and monitored esophageal pressure to performed transpulmonary pressure guided PEEP titration. When we changed PEEP from 8 to 15 cmH2O so that the end-expiratory transpulmonary pressure achieving 0 to 5 cmH2O, her oxygenation(PaO2/FIO2 ratio : 55 to 178 mmHg)and respiratory compliance(1.4 to 3.0 mL/cmH2O)were dramatically improved. Her respiratory condition was further stabilized by ascites puncture and radiotherapy, and the patient was extubated successfully on the 25th ICU day. Conclusions : Although pediatric neuroblastoma with stage 4S may induce severe respiratory efficiency, the responsiveness of treatment for neuroblastoma is promising. Multimodal treatments including optimal ventilator management such as transpulmonary pressure -guided PEEP titration contributes to improved patient's prognosis. (キーワード) Neuroblastoma / Abdominal compartment syndrome / Transpulmonary pressure (文献検索サイトへのリンク) ● CiNii @ 国立情報学研究所 (CRID): 1050867133848820608 (CiNii: 1050867133848820608)
6.	Taiga Itagaki, Yusuke Akimoto, Yuki Nakano, Yoshitoyo Ueno, Manabu Ishihara, Natsuki Tane, Yumiko Tsunano and Jun Oto : Relationships between double cycling and inspiratory effort with diaphragm thickness during the early phase of mechanical ventilation: A prospective observational study., PLoS ONE, 17, 8, 2022. (要約) Double cycling on the third day of mechanical ventilation was associated with strong inspiratory efforts and, possibly, changes in diaphragm thickness. (キーワード) 成人 (adult) / Aged / Diaphragm / Humans / Positive-Pressure Respiration / Respiration, Artificial / Retrospective Studies / Ventilators, Mechanical (徳島大学機関リポジトリ) ● Metadata: 2011720 (出版サイトへのリンク) ● Publication site (DOI): 10.1371/journal.pone.0273173 (文献検索サイトへのリンク) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 35976965 ● Search Scopus @ Elsevier (PMID): 35976965 ● Search Scopus @ Elsevier (DOI): 10.1371/journal.pone.0273173 (徳島大学機関リポジトリ: 2011720, DOI: 10.1371/journal.pone.0273173, PubMed: 35976965)
7.	Yoshitoyo Ueno, Saki Harada, Koji Sato, Kazuki Momota, Hiroki Sato, Yusuke Akimoto, Yuta Arai, Toshiyuki Nunomura, Manabu Ishihara, Natsuki Tane, Taiga Itagaki, Yasuhiko Nishioka and Jun Oto : Independent lung ventilation for the management of acute allograft rejection after single-lung transplantation for end-stage emphysema., The Journal of Medical Investigation : JMI, 69, 3.4, 323-327, 2022. (要約) Background : We herein report the use of independent lung ventilation (ILV) for managing acute allograft rejection after single-lung transplantation (SLT) for end-stage emphysema. Case presentation : A 54-year-old woman was transferred to our hospital with severe hypoxemia and respiratory distress due to unilateral lung disease with diffuse alveolar damage in the right donor lung associated with acute allograft rejection and with hyperinflation of the left native lung due to emphysema. She was unresponsive to immunosuppressive medications and conventional ventilation strategies, so different ventilator settings for each lung were required. A double-lumen endotracheal tube (DLT) was inserted, and ILV was initiated. The right lung was ventilated with high positive end-expiratory pressure (PEEP), intended for lung recruitment, and the left lung was ventilated with lung protective strategies using a low tidal volume and low levels of PEEP to avoid hyperinflation. Two days later, her lung function was dramatically improved, and the DLT was replaced with a single-lumen endotracheal tube. Gas exchange was maintained, and she was successfully weaned from mechanical ventilation on intensive-care unit day 15. Conclusions : ILV appears to be effective and safe for managing acute allograft rejection after SLT for emphysema. J. Med. Invest. 69 : 323-327, August, 2022. (キーワード) Allografts / Emphysema / Female / Humans / Lung / Lung Transplantation / Middle Aged / Pulmonary Emphysema / Respiration, Artificial (出版サイトへのリンク) ● Publication site (DOI): 10.2152/jmi.69.323 (文献検索サイトへのリンク) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 36244790 ● Search Scopus @ Elsevier (PMID): 36244790 ● Search Scopus @ Elsevier (DOI): 10.2152/jmi.69.323 (DOI: 10.2152/jmi.69.323, PubMed: 36244790)
8.	Yusuke Akimoto, Natsuki Bando, Hiroki Sato, Koji Sato, Kazuki Momota, Toshiyuki Nunomura, Yoshitoyo Ueno, Manabu Ishihara, Natsuki Tane, Taiga Itagaki and Jun Oto : Acquired laryngomalacia as a cause of post-extubation respiratory failure in patient with postoperative seizure and central pontine myelinolysis after craniotomy., The Journal of Medical Investigation : JMI, 69, 3.4, 316-319, 2022. (要約) Background : Laryngomalacia is a congenital abnormality of the larynx that commonly occurs in children and rarely in adults. We report the first case of acquired laryngomalacia mainly due to postoperative seizure and central pontine myelinolysis after scheduled craniotomy. Case presentation : A 69-year-old man was admitted to the hospital for elective craniotomy for craniopharyngioma. After the surgery, he developed refractory seizure and required intubation and mechanical ventilation in the intensive-care unit (ICU). After treatment for the seizure, he was extubated. However, immediately after extubation, he developed stridor and respiratory retraction. We performed fiberoptic laryngoscopy and confirmed that the epiglottis had collapsed into the posterior wall of the pharynx during inspiration, which was suspected to be laryngomalacia. He received invasive mechanical ventilation for two days following re-extubation. After the second extubation, he developed stridor again due to acquired laryngomalacia. Six days later, his respiratory condition had worsened, and he received re-intubation and tracheostomy. After ICU discharge, central pontine myelinolysis was diagnosed by magnetic resonance imaging. Conclusions : Adult-onset laryngomalacia is a rare cause of upper airway obstruction but should be considered as a cause of postoperative extubation failure. We should not delay performing fiberoptic laryngoscopy to evaluate this pathology and provide optimal treatment. J. Med. Invest. 69 : 316-319, August, 2022. (キーワード) Aged / Airway Extubation / Child / Craniotomy / Humans / Laryngomalacia / Laryngoscopy / Male / Myelinolysis, Central Pontine / Respiratory Insufficiency / Respiratory Sounds / Seizures (出版サイトへのリンク) ● Publication site (DOI): 10.2152/jmi.69.316 (文献検索サイトへのリンク) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 36244788 ● CiNii @ 国立情報学研究所 (CRID): 1390856738295204480 ● Search Scopus @ Elsevier (PMID): 36244788 ● Search Scopus @ Elsevier (DOI): 10.2152/jmi.69.316 (DOI: 10.2152/jmi.69.316, PubMed: 36244788, CiNii: 1390856738295204480)
9.	Yoshitoyo Ueno, Koji Sato, Kazuki Momota, Hiroki Sato, Yuki Nakano, Yusuke Akimoto, Toshiyuki Nunomura, Natsuki Tane, Taiga Itagaki and Jun Oto : The quality and quantity of sleep on dexmedetomidine during high-flow nasal cannula oxygen therapy in critically ill patients., The Journal of Medical Investigation : JMI, 69, 3.4, 266-272, 2022. (要約) Purpose : High-flow nasal cannula oxygen therapy (HFNC) is a new type of non-invasive respiratory support for acute respiratory failure patients. However, patients receiving HFNC often develop sleep disturbances. We therefore examined whether dexmedetomidine could preserve the sleep characteristics in patients who underwent HFNC. Patients and Methods : This was a pilot, randomized controlled study. We assigned critically ill patients treated with HFNC to receive dexmedetomidine (0.2 to 0.7 µg / kg / h, DEX group) or not (non-DEX group) at night (9:00 p.m. to 6:00 a.m.). Polysomnograms were monitored during the study period. The primary outcomes were total sleep time (TST), sleep efficiency and duration of stage 2 non-rapid eye movement (stage N2) sleep. Results : Of the 28 patients who underwent randomization, 24 were included in the final analysis (12 patients per group). Dexmedetomidine increased the TST (369 min vs. 119 min, p = 0.024) and sleep efficiency (68% vs. 22%, P = 0.024). The duration of stage N2 was increased in the DEX group compared with the non-DEX group, but this finding did not reach statistical significance. The incidences of respiratory depression and hemodynamic instability were similar between the two groups. Conclusions : In critically ill patients who underwent HFNC, dexmedetomidine may optimize the sleep quantity without any adverse events. J. Med. Invest. 69 : 266-272, August, 2022. (キーワード) Cannula / Critical Illness / Dexmedetomidine / Humans / Oxygen / Sleep (徳島大学機関リポジトリ) ● Metadata: 2008910 (出版サイトへのリンク) ● Publication site (DOI): 10.2152/jmi.69.266 (文献検索サイトへのリンク) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 36244779 ● CiNii @ 国立情報学研究所 (CRID): 1390293788341782528 ● Search Scopus @ Elsevier (PMID): 36244779 ● Search Scopus @ Elsevier (DOI): 10.2152/jmi.69.266 (徳島大学機関リポジトリ: 2008910, DOI: 10.2152/jmi.69.266, PubMed: 36244779, CiNii: 1390293788341782528)

国際会議:

1.	Yusuke Akimoto, Takuya Takashima, Taiga Itagaki and Jun Oto : Ultrasound evaluation of expiratory muscle activity during high-flow nasal cannula oxygen therapy in critically ill patients., ESICM LIVES 2024 Congress(October 5-9, Barcelona), Barcelona, Oct. 2024.

国内講演発表:

1.	秋本雄祐, 板垣大雅, 髙島拓也, 大藤純 : High-flow nasal cannulaが呼吸筋に与える影響:クロスオーバーランダム化試験．, 第52回日本集中治療医学会学術集会(3月14∼16日，福岡市), 2025年3月.
2.	秋本雄祐, 板垣大雅, 岡本尚裕, 大藤純 : Expiratory flow limitationによる換気不全で人工呼吸管理に難渋した1例．, 第46回日本呼吸療法医学会学術集会(6月28∼29日，天童市), 2024年6月.
3.	秋本雄祐, 板垣大雅 : パネルディスカッション:呼吸管理戦略を標す:患者人工呼吸器不同調は治療対象となる現象なのか?「横隔膜保護の観点からみた患者-人工呼吸器非同調」, 2024年6月.
4.	秋本雄祐, 板東夏生, 佐藤功志, 佐藤裕紀, 百田和貴, 石原学, 上野義豊, 田根なつ紀, 板垣大雅, 大藤純 : リーク補正機能が原因と考えられたミストリガの3例．(優秀演題), 第45回日本呼吸療法医学会学術集会, 2023年8月.
5.	板垣大雅, 秋本雄祐, 髙島拓也, 大藤純 : シンポジウム6:自発呼吸努力―どのように評価し，管理すべきか―「呼気筋動員の功罪∼オピオイドの影響など∼」, 第45回日本呼吸療法医学会学術集会, 2023年8月.
6.	板東夏生, 百田和貴, 佐藤功志, 佐藤裕紀, 秋本雄祐, 布村俊幸, 石原学, 上野義豊, 田根なつ紀, 板垣大雅, 大藤純 : セツキシマブ投与後のインフュージョンリアクションから心停止に至るも後遺症なく救命できた一症例．, 第39回日本救急医学会中国四国地方会, 2023年7月.
7.	秋本雄祐 : 電気インピーダンストモグラフィを用いて体位変換によるparadoxical responseを評価した1例．, 第34回日本臨床モニター学会総会, 2023年4月.
8.	百田和貴, 板東夏生, 佐藤功志, 佐藤裕紀, 秋本雄祐, 布村俊幸, 上野義豊, 田根なつ紀, 板垣大雅, 大藤純 : 非侵襲的陽圧換気中に縦隔気腫を来したCOVID-19肺炎の一症例．, 第50回日本集中治療医学会学術集会, 2023年3月.
9.	秋本雄祐, 板東夏生, 佐藤功志, 佐藤裕紀, 百田和貴, 石原学, 上野義豊, 田根なつ紀, 板垣大雅, 大藤純 : 予定開頭手術後の橋中心髄鞘崩壊症が原因と考えられた成人喉頭軟化症の一症例．, 第50回日本集中治療医学会学術集会, 2023年3月.
10.	板東夏生, 上野義豊, 百田和貴, 佐藤功志, 佐藤裕紀, 秋本雄祐, 石原学, 田根なつ紀, 板垣大雅, 大藤純 : 電気インピーダンス・トモグラフィにて閉塞性無気肺を疑い，早期介入に至った重症COVID-19症例．, 第50回日本集中治療医学会学術集会, 2023年3月.
11.	佐藤裕紀, 板東夏生, 百田和貴, 佐藤功志, 佐藤裕紀, 秋本雄祐, 石原学, 田根なつ紀, 板垣大雅, 大藤純 : 開心術周術期の出血量や輸血量が術後再開胸止血術の頻度に与える影響．, 第50回日本集中治療医学会学術集会, 2023年3月.
12.	中野勇希, 佐藤功志, 佐藤裕紀, 百田和貴, 秋本雄祐, 布村俊幸, 上野義豊, 田根なつ紀, 板垣大雅, 大藤純 : 気管切開後25年間無症候性に経過した声門下狭窄が気管挿管を機に増悪し，術後抜管困難となった一症例, 第50回日本集中治療医学会学術集会, 2023年3月.
13.	上野義豊, 百田和貴, 佐藤功志, 佐藤裕紀, 秋本雄祐, 布村俊幸, 石原学, 田根なつ紀, 板垣大雅, 大藤純 : 末期肺気腫に対する片肺移植後の急性拒絶反応に対し，分離肺換気が奏功した一症例, 第50回日本集中治療医学会学術集会, 2023年3月.
14.	上野義豊, 佐藤裕紀, 百田和貴, 佐藤功志, 秋本雄祐, 布村俊幸, 石原学, 田根なつ紀, 板垣大雅, 大藤純 : 開心術後患者における乳酸値ピークアウトまでの時間と術後経過との関連, 第50回日本集中治療医学会学術集会, 2023年3月.
15.	佐藤功志, 上野義豊, 佐藤裕紀, 百田和貴, 秋本雄祐, 布村俊幸, 石原学, 田根なつ紀, 板垣大雅, 大藤純 : VA-ECMO, 第50回日本集中治療医学会学術集会, 2023年3月.
16.	中野勇希, 佐藤功志, 佐藤裕紀, 百田和貴, 秋本雄祐, 布村俊幸, 上野義豊, 田根なつ紀, 板垣大雅, 大藤純 : 高位気管切開既往患者に生じた声門下狭窄および気管軟化症により術後抜管困難となった一症例, 第6回徳島外科学会, 2023年2月.
17.	板東夏生, 宮本憲哉, 百田和貴, 佐藤功志, 佐藤裕紀, 秋本雄祐, 布村俊幸, 石原学, 上野義豊, 田根なつ紀, 板垣大雅, 大藤純 : セツキシマブ投与後のインフュージョンリアクションから心停止に至るも後遺症なく救命できた一症例, 第6回徳島外科学会, 2023年2月.
18.	秋本雄祐 : シンポジスト「シンポジウム．DIC の治療意義について」, 第2回南四国・集中治療医学シンポジウム, 2022年11月.
19.	秋本雄祐, 板東夏生, 佐藤功志, 佐藤裕紀, 百田和貴, 石原学, 上野義豊, 田根なつ紀, 板垣大雅, 大藤純 : くも膜下出血後のたこつぼ心筋症および神経原性肺水腫に対してバゾプレシンを用いて循環管理を行った1例．, 第50回日本救急医学会総会・学術集会, 2022年10月.
20.	百田和貴, 板東夏生, 佐藤功志, 佐藤裕紀, 秋本雄祐, 布村俊幸, 石原学, 上野義豊, 田根なつ紀, 板垣大雅, 大藤純 : 重篤な循環不全を呈した重症レジオネラ肺炎に対しVA-ECMO導入により救命した1例．, 第50回日本救急医学会総会・学術集会, 2022年10月.
21.	上野義豊, 秋本雄祐, 中野勇希, 石原学, 佐藤功志, 佐藤裕紀, 百田和貴, 田根なつ紀, 綱野祐美子, 板垣大雅, 大藤純 : 重症COVID-19患者の転院および救急搬送における問題点の検討．, 第49回日本救急医学会総会・学術集会, 2021年11月.
22.	中野勇希, 佐藤功志, 佐藤裕紀, 百田和貴, 秋本雄祐, 上野義豊, 石原学, 田根なつ紀, 綱野祐美子, 板垣大雅, 大藤純 : 腹部コンパートメント症候群による呼吸不全をきたした小児神経芽腫Stage 4Sの一症例．, 第49回日本救急医学会総会・学術集会, 2021年11月.
23.	上野義豊, 秋本雄祐, 中野勇希, 石原学, 荒瀬美晴, 百田和貴, 佐藤功志, 佐藤裕紀, 田根なつ紀, 綱野祐美子, 板垣大雅, 大藤純 : 重症COVID-19患者の転院および救急搬送における問題点の検討．, 第1回南四国・集中治療医学フォーラム, 2021年11月.
24.	板垣大雅, 秋本雄祐, 中野勇希, 上野義豊, 石原学, 田根なつ紀, 綱野祐美子, 大藤純 : 人工呼吸開始後早期のdouble cyclingが横隔膜厚の変化に与える影響．, 第43回日本呼吸療法医学会学術集会, 2021年7月.

特任助教 : 秋本雄祐

研究活動

専門分野

研究テーマ

著書・論文

著書:

学術論文(審査論文):

国際会議:

国内講演発表:

特任助教 : 秋本 雄祐

研究活動

専門分野

研究テーマ

著書・論文

著書:

学術論文(審査論文):

国際会議:

国内講演発表:

特任助教 : 秋本雄祐