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Research

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Field of Study

Virology

Subject of Study

HIV/SIVの複製と病原性に関する分子遺伝学的研究 (AIDS, HIV, SIV, Gag, アクセサリー蛋白質)

Book / Paper

Book:

1. Masako Nomaguchi, Doi Naoya, Fujiwara Sachi and Akio Adachi :
Macaque-tropic HIV-1 derivatives: a novel experimental approach to understand viral replication and evolution in vivo.,
2011.

Academic Paper (Judged Full Paper):

1. Takaaki Koma, Tokifumi Odaka, Sung-il Lee, Naoya Doi, Tomoyuki Kondo, Kazu Okuma, Jun-Ichi Fujisawa, Akio Adachi and Masako Nomaguchi :
Humanized mice generated by intra-bone marrow injection of CD133-positive hematopoietic stem cells: application to HIV-1 research,
Frontiers in Virology, Vol.3, 2023.
(DOI: 10.3389/fviro.2023.1192184)
2. Akio Adachi, Takaaki Koma and Masako Nomaguchi :
Editorial: HIV/SIV basic research update,
Frontiers in Virology, Vol.3, 2023.
(DOI: 10.3389/fviro.2023.1253524)
3. Takaaki Koma, Naoya Doi, Akihiro Suzuki, Kentaro Nagamatsu, Takeshi Yasui, Koji Yasutomo, Akio Adachi, Takeo Minamikawa and Masako Nomaguchi :
Major target for UV-induced complete loss of HIV-1 infectivity: A model study of single-stranded RNA enveloped viruses,
Frontiers in Virology, Vol.2, 994842, 2022.
(DOI: 10.3389/fviro.2022.994842)
4. Takaaki Koma, Naoya Doi, Mai Takemoto, Kyosuke Watanabe, Hideki Yamamoto, Satoshi Nakashima, Akio Adachi and Masako Nomaguchi :
The Expression Level of HIV-1 Vif Is Optimized by Nucleotide Changes in the Genomic SA1D2prox Region during the Viral Adaptation Process.,
Viruses, Vol.13, No.10, 2021.
(Tokushima University Institutional Repository: 116870,   DOI: 10.3390/v13102079,   PubMed: 34696508)
5. Takaaki Koma, Masaru Yokoyama, Osamu Kotani, Naoya Doi, Nina Nakanishi, Hayato Okubo, Shun Adachi, Akio Adachi, Hironori Sato and Masako Nomaguchi :
Species-specific valid ternary interactions of HIV-1 Env-gp120, CD4, and CCR5 as revealed by an adaptive single-amino acid substitution at the V3 loop tip.,
Journal of Virology, 2021.
(Tokushima University Institutional Repository: 116583,   DOI: 10.1128/JVI.02177-20,   PubMed: 33883222)
6. Naoya Doi, Takaaki Koma, Akio Adachi and Masako Nomaguchi :
Expression Level of HIV-1 Vif Can Be Fluctuated by Natural Nucleotide Variations in the vif-Coding and Regulatory SA1D2prox Sequences of the Proviral Genome.,
Frontiers in Microbiology, Vol.10, 2019.
(Tokushima University Institutional Repository: 114460,   DOI: 10.3389/fmicb.2019.02758,   PubMed: 31849897)
7. Naoya Doi, Takaaki Koma, Akio Adachi and Masako Nomaguchi :
Role for Gag-CA Interdomain Linker in Primate Lentiviral Replication.,
Frontiers in Microbiology, Vol.10, 2019.
(Tokushima University Institutional Repository: 114459,   DOI: 10.3389/fmicb.2019.01831,   PubMed: 31440231)
8. Takaaki Koma, Osamu Kotani, Kei Miyakawa, Akihide Ryo, Masaru Yokoyama, Naoya Doi, Akio Adachi, Hironori Sato and Masako Nomaguchi :
Allosteric regulation of HIV-1 capsid structure for Gag assembly, virion production, and viral infectivity by a disordered interdomain linker.,
Journal of Virology, 2019.
(DOI: 10.1128/JVI.00381-19,   PubMed: 31189701)
9. Naoya Doi, Masaru Yokoyama, Takaaki Koma, Osamu Kotani, Hironori Sato, Akio Adachi and Masako Nomaguchi :
Concomitant Enhancement of HIV-1 Replication Potential and Neutralization-Resistance in Concert With Three Adaptive Mutations in Env V1/C2/C4 Domains.,
Frontiers in Microbiology, Vol.10, 2019.
(Tokushima University Institutional Repository: 114458,   DOI: 10.3389/fmicb.2019.00002,   PubMed: 30705669,   Elsevier: Scopus)
10. Naoya Doi, Tomoyuki Miura, Hiromi Mori, Hiromi Sakawaki, Takaaki Koma, Akio Adachi and Masako Nomaguchi :
CXCR4- and CCR5-Tropic HIV-1 Clones Are Both Tractable to Grow in Rhesus Macaques.,
Frontiers in Microbiology, Vol.9, 2018.
(Tokushima University Institutional Repository: 114457,   DOI: 10.3389/fmicb.2018.02510,   PubMed: 30405570)
11. Shoko Nakanishi, Sakimi Watanabe, Naoya Doi, Takaaki Koma, Akio Adachi and Masako Nomaguchi :
Virological characterization of HIV-1 CA-NTD mutants constructed in a virus-lineage reflected manner.,
The Journal of Medical Investigation : JMI, Vol.65, No.1.2, 110-115, 2018.
(Tokushima University Institutional Repository: 111440,   DOI: 10.2152/jmi.65.110,   PubMed: 29593179)
12. Masako Nomaguchi, Naoya Doi, Tomoya Yoshida, Takaaki Koma, Shun Adachi, Hirotaka Ode, Yasumasa Iwatani, Masaru Yokoyama, Hironori Sato and Akio Adachi :
mRNA Is Modulated by Natural Nucleotide Variations and SLSA1 RNA Structure in SA1D2prox Genomic Region.,
Frontiers in Microbiology, Vol.8, No.2542, 2017.
(Tokushima University Institutional Repository: 114455,   DOI: 10.3389/fmicb.2017.02542,   PubMed: 29326677,   Elsevier: Scopus)
13. Masako Nomaguchi, Naoya Doi, Takaaki Koma and Akio Adachi :
Complete Genome Sequences of Human Immunodeficiency Type 1 Viruses Genetically Engineered To Be Tropic for Rhesus Macaques.,
Genome Announcements, Vol.5, No.39, 2017.
(Tokushima University Institutional Repository: 115106,   DOI: 10.1128/genomeA.01063-17,   PubMed: 28963223)
14. Masako Nomaguchi and Akio Adachi :
Editorial: Highly Mutable Animal RNA Viruses* Adaptation and Evolution,
Frontiers in Microbiology, Vol.8, 2017.
(Tokushima University Institutional Repository: 114454,   DOI: 10.3389/fmicb.2017.01785,   PubMed: 28966612)
15. Naoya Doi, Yosuke Sakai, Akio Adachi and Masako Nomaguchi :
Generation and characterization of new CCR5-tropic HIV-1rmt clones,
The Journal of Medical Investigation : JMI, Vol.64, No.3,4, 272-279, 2017.
(Tokushima University Institutional Repository: 111132,   DOI: 10.2152/jmi.64.272,   PubMed: 28954995)
16. Yasuyuki Miyazaki, Naoya Doi, Takaaki Koma, Akio Adachi and Masako Nomaguchi :
Novel In Vitro Screening System Based on Differential Scanning Fluorimetry to Search for Small Molecules against the Disassembly or Assembly of HIV-1 Capsid Protein.,
Frontiers in Microbiology, Vol.8, 1413, 2017.
(Tokushima University Institutional Repository: 114450,   DOI: 10.3389/fmicb.2017.01413,   PubMed: 28791001)
17. Yasuyuki Miyazaki, Ariko Miyake, Noya Doi, Takaaki Koma, Tsuneo Uchiyama, Akio Adachi and Masako Nomaguchi :
Comparison of Biochemical Properties of HIV-1 and HIV-2 Capsid Proteins.,
Frontiers in Microbiology, Vol.8, No.1, 1082, 2017.
(Tokushima University Institutional Repository: 114452,   DOI: 10.3389/fmicb.2017.01082,   PubMed: 28659897)
18. Yosuke Sakai, Naoya Doi, Yasuyuki Miyazaki, Akio Adachi and Masako Nomaguchi :
Phylogenetic Insights into the Functional Relationship between Primate Lentiviral Reverse Transcriptase and Accessory Proteins Vpx/Vpr.,
Frontiers in Microbiology, Vol.7, 2016.
(Tokushima University Institutional Repository: 114413,   DOI: 10.3389/fmicb.2016.01655,   PubMed: 27803699)
19. Yosuke Sakai, Ariko Miyake, Naoya Doi, Hikari Sasada, Yasuyuki Miyazaki, Akio Adachi and Masako Nomaguchi :
Expression Profiles of Vpx/Vpr Proteins Are Co-related with the Primate Lentiviral Lineage.,
Frontiers in Microbiology, Vol.7, 2016.
(Tokushima University Institutional Repository: 114412,   DOI: 10.3389/fmicb.2016.01211,   PubMed: 27536295)
20. Masako Nomaguchi, N. Doi, Y. Sakai, H. Ode, Y. Iwatani, T. Ueno, Y. Matsumoto, Y. Miyazaki, T. Masuda and Akio Adachi :
Natural single-nucleotide variations in the HIV-1 genomic SA1prox region can alter viral replication ability by regulating Vif expression levels.,
Journal of Virology, Vol.90, No.9, 4563-4578, 2016.
(DOI: 10.1128/JVI.02939-15,   PubMed: 26912631,   Elsevier: Scopus)
21. M. Yokoyama, Masako Nomaguchi, N. Doi, T. Kanda, Akio Adachi and H. Sato :
In silico analysis of HIV-1 Env-gp20 reveals structural bases for viral adaptation in growth-restrictive cells.,
Frontiers in Microbiology, Vol.7, No.110, 2016.
(Tokushima University Institutional Repository: 114410,   DOI: 10.3389/fmicb.2016.00110,   PubMed: 26903989)
22. Tahmina Sultana, E Emi Nakayama, Satoshi Tobita, Masaru Yokoyama, Yohei Seki, Akatsuki Saito, Masako Nomaguchi, Akio Adachi, Hirofumi Akari, Hironori Sato and Tatsuo Shioda :
Novel mutant human immunodeficiency virus type 1 strains with high degree of resistance to cynomolgus macaque TRIMCyp generated by random mutagenesis.,
The Journal of General Virology, Vol.97, No.4, 963-976, 2016.
(Tokushima University Institutional Repository: 115516,   DOI: 10.1099/jgv.0.000408,   PubMed: 26795727,   Elsevier: Scopus)
23. Naoya Doi, Yosuke Sakai, Yasuyuki Miyazaki, Akio Adachi and Masako Nomaguchi :
Single-amino acid mutation 66SR in Gag-matrix enhances viral single-cycle infectivity of R5-tropic HIV-1rmt.,
The Journal of Medical Investigation : JMI, Vol.62, No.3-4, 228-232, 2015.
(Tokushima University Institutional Repository: 111284,   DOI: 10.2152/jmi.62.228,   PubMed: 26399353,   Elsevier: Scopus)
24. Akio Adachi and Tomoyuki Miura :
Animal model studies on viral infections.,
Frontiers in Microbiology, Vol.5, No.672, 2014.
(DOI: 10.3389/fmicb.2014.00672,   PubMed: 25520715,   Elsevier: Scopus)
25. Masako Nomaguchi, Emi E. Nakayama, Masaru Yokoyama, Naoya Doi, Tatsuhiko Igarashi, Tatsuo Shioda, Hironori Sato and Akio Adachi :
Distinct combinations of amino acid substitutions in N-terminal domain of Gag-capsid afford HIV-1 resistance to rhesus TRIM5α.,
Microbes and Infection, Vol.16, No.11, 936-944, 2014.
(DOI: 10.1016/j.micinf.2014.08.017,   PubMed: 25195168)
26. Masako Nomaguchi, Naoya Doi and Akio Adachi :
Virological characterization of HIV-2 vpx gene mutants in various cell systems.,
Microbes and Infection, Vol.16, No.8, 695-701, 2014.
(DOI: 10.1016/j.micinf.2014.06.004,   PubMed: 24956595)
27. Masako Nomaguchi, Ariko Miyake, Naoya Doi, Sachi Fujiwara, Yasuyuki Miyazaki, Yasuko Tsunetsugu-Yokota, Masaru Yokoyama, Hironori Sato, Takao Masuda and Akio Adachi :
Natural single-nucleotide polymorphisms in the 3' region of the HIV-1 pol gene modulate viral replication ability.,
Journal of Virology, Vol.88, No.8, 4145-4160, 2014.
(DOI: 10.1128/JVI.01859-13,   PubMed: 24478432,   Elsevier: Scopus)
28. Ariko Miyake, Yasuyuki Miyazaki, Mikako Fujita, Masako Nomaguchi and Akio Adachi :
Role of poly-proline motif in HIV-2 Vpx expression.,
Frontiers in Microbiology, Vol.5, 24, 2014.
(DOI: 10.3389/fmicb.2014.00024,   PubMed: 24478770,   Elsevier: Scopus)
29. Naoya Doi, Akio Adachi and Masako Nomaguchi :
Growth properties of macaque-tropic HIV-1 clones carrying vpr/vpx genes derived from simian immunodeficiency viruses in place of their vpr regions.,
The Journal of Medical Investigation : JMI, Vol.61, No.3-4, 374-379, 2014.
(Tokushima University Institutional Repository: 109587,   DOI: 10.2152/jmi.61.374,   PubMed: 25264057,   Elsevier: Scopus)
30. Ariko Miyake, Mikako Fujita, Haruna Fujino, Ryoko Koga, Sogo Kawamura, Masami Otsuka, Hirotaka Ode, Yasumasa Iwatani, Yosuke Sakai, Naoya Doi, Masako Nomaguchi, Akio Adachi and Yasuyuki Miyazaki :
Poly-proline motif in HIV-2 Vpx is critical for its efficient translation.,
The Journal of General Virology, Vol.95, No.Pt 1, 179-189, 2013.
(DOI: 10.1099/vir.0.057364-0,   PubMed: 24114794)
31. Masako Nomaguchi, Masaru Yokoyama, Ken Kono, E Emi Nakayama, Tatsuo Shioda, Naoya Doi, Sachi Fujiwara, Akatsuki Saito, Hirofumi Akari, Kei Miyakawa, Akihide Ryo, Hirotaka Ode, Yasumasa Iwatani, Tomoyuki Miura, Tatsuhiko Igarashi, Hironori Sato and Akio Adachi :
Generation of Rhesus Macaque-Tropic HIV-1 Clones That Are Resistant to Major Anti-HIV-1 Restriction Factors.,
Journal of Virology, Vol.87, No.21, 11447-11461, 2013.
(DOI: 10.1128/JVI.01549-13,   PubMed: 23966385)
32. Naoya Doi, Ayaka Okubo, Mizumo Yamane, Yosuke Sakai, Akio Adachi and Masako Nomaguchi :
Growth potentials of CCR5-tropic/CXCR4-tropic HIV-1mt clones in macaque cells.,
Frontiers in Microbiology, Vol.4, No.218.doi:10.3389/fmicb.2013.00218., 2013.
(DOI: 10.3389/fmicb.2013.00218,   PubMed: 23908651)
33. Akatsuki Saito, Masako Nomaguchi, Ken Kono, Yasumasa Iwatani, Masaru Yokoyama, Yasuhiro Yasutomi, Hironori Sato, Tatsuo Shioda, Wataru Sugiura, Tetsuro Matano, Akio Adachi, E Emi Nakayama and Hirofumi Akari :
TRIM5 genotypes in cynomolgus monkeys primarily influence inter-individual diversity in susceptibility to monkey-tropic human immunodeficiency virus type 1.,
The Journal of General Virology, Vol.94, No.Pt 6, 1318-1324, 2013.
(DOI: 10.1099/vir.0.050252-0,   PubMed: 23486671)
34. Masako Nomaguchi, Naoya Doi, Sachi Fujiwara, Akatsuki Saito, Hirofumi Akari, E Emi Nakayama, Tatsuo Shioda, Masaru Yokoyama, Hironori Sato and Akio Adachi :
Systemic biological analysis of the mutations in two distinct HIV-1mt genomes occurred during replication in macaque cells.,
Microbes and Infection, Vol.15, No.4, 319-328, 2013.
(DOI: 10.1016/j.micinf.2013.01.005,   PubMed: 23384722)
35. Masako Nomaguchi, Masaru Yokoyama, Ken Kono, E Emi Nakayama, Tatsuo Shioda, Akatsuki Saito, Hirofumi Akari, Yasuhiro Yasutomi, Tetsuro Matano, Hironori Sato and Akio Adachi :
Gag-CA Q110D mutation elicits TRIM5-independent enhancement of HIV-1mt replication in macaque cells.,
Microbes and Infection, Vol.15, No.1, 56-65, 2013.
(DOI: 10.1016/j.micinf.2012.10.013,   PubMed: 23123544)
36. Kei Miyakawa, Tatsuya Sawasaki, Satoko Matsunaga, Andrey Tokarev, Gary Quinn, Hirokazu Kimura, Masako Nomaguchi, Akio Adachi, Naoki Yamamoto, John Guatelli and Akihide Ryo :
Interferon-induced SCYL2 limits release of HIV-1 by triggering PP2A-mediated dephosphorylation of the viral protein Vpu.,
Science Signaling, Vol.5, No.245: ra73, 2012.
(DOI: 10.1126/scisignal.2003212,   PubMed: 23047923)
37. Mikako Fujita, Masako Nomaguchi, Akio Adachi and Masami Otsuka :
SAMHD1-Dependent and -Independent Functions of HIV-2/SIV Vpx Protein.,
Frontiers in Microbiology, Vol.3, No.297.doi:10.3389/fmicb.2012.00297., 2012.
(DOI: 10.3389/fmicb.2012.00297,   PubMed: 22908011)
38. Masako Nomaguchi, Mikako Fujita, Yasuyuki Miyazaki and Akio Adachi :
Viral tropism.,
Frontiers in Microbiology, Vol.3, No.281.doi:10.3389/fmicb.2012.00281., 2012.
(DOI: 10.3389/fmicb.2012.00281,   PubMed: 22876241)
39. Masako Nomaguchi, Naoya Doi, Yui Matsumoto, Yosuke Sakai, Sachi Fujiwara and Akio Adachi :
Species tropism of HIV-1 modulated by viral accessory proteins.,
Frontiers in Microbiology, Vol.3, No.267.doi:10.3389/fmicb.2012.00267., 2012.
(DOI: 10.3389/fmicb.2012.00267,   PubMed: 22855686)
40. Yasuyuki Miyazaki, Mikako Fujita, Masako Nomaguchi and Akio Adachi :
Structural biology for virus research.,
Frontiers in Microbiology, Vol.3, No.91.doi:10.3389/fmicb.2012.00091, 2012.
(DOI: 10.3389/fmicb.2012.00091,   PubMed: 22419916)
41. Akatsuki Saito, Ken Kono, Masako Nomaguchi, Yasuhiro Yasutomi, Akio Adachi, Tatsuo Shioda, Hirofumi Akari and E Emi Nakayama :
Geographical, genetic and functional diversity of antiretroviral host factor TRIMCyp in cynomolgus macaque (Macaca fascicularis).,
The Journal of General Virology, Vol.93, No.Pt 3, 594-602, 2012.
(DOI: 10.1099/vir.0.038075-0,   PubMed: 22113010)
42. Yasuyuki Miyazaki, Ariko Miyake, Masako Nomaguchi and Akio Adachi :
Structural dynamics of retroviral genome and the packaging.,
Frontiers in Microbiology, Vol.2, No.264.doi:10.3389/fmicb.2011.00264, 2011.
(DOI: 10.3389/fmicb.2011.00264,   PubMed: 22232618)
43. Nopporn Chutiwitoonchai, Masateru Hiyoshi, Philip Mwimanzi, Takamasa Ueno, Akio Adachi, Hirotaka Ode, Hironori Sato, T Oliver Fackler, Seiji Okada and Shinya Suzu :
The identification of a small molecule compound that reduces HIV-1 Nef-mediated viral infectivity enhancement.,
PLoS ONE, Vol.6, No.11, e27696, 2011.
(DOI: 10.1371/journal.pone.0027696,   PubMed: 22110726)
44. Shun Adachi, Akio Adachi and Masako Nomaguchi :
Commentary on a New Era of Investigating 3D Structure-Based Human-Virus Protein Network Dynamics.,
Frontiers in Microbiology, Vol.2, No.186.doi:10.3389/fmicb.2011.00186., 2011.
(DOI: 10.3389/fmicb.2011.00186,   PubMed: 21927614)
45. Masako Nomaguchi, Mikako Fujita and Akio Adachi :
The Fourth Major Restriction Factor Against HIV/SIV.,
Frontiers in Microbiology, Vol.2, No.132.doi:10.3389/fmicb.2011.00132., 2011.
(DOI: 10.3389/fmicb.2011.00132,   PubMed: 21713064)
46. Hideki Fujii, Manabu Ato, Yoshimasa Takahashi, Kaori Otake, Shu-Ichi Hashimoto, Tomohiro Kaji, Yasuko Tsunetsugu-Yokota, Mikako Fujita, Akio Adachi, Toshinori Nakayama, Masaru Taniguchi, Shigeo Koyasu and Toshitada Takemori :
HIV-1 Nef impairs multiple T-cell functions in antigen-specific immune response in mice.,
International Immunology, Vol.23, No.7, 433-441, 2011.
(DOI: 10.1093/intimm/dxr031,   PubMed: 21642447,   Elsevier: Scopus)
47. Naoya Doi, Sachi Fujiwara, Akio Adachi and Masako Nomaguchi :
Rhesus M1.3S Cells Suitable for Biological Evaluation of Macaque-Tropic HIV/SIV Clones.,
Frontiers in Microbiology, Vol.2, No.115.doi:10.3389/fmicb.2011.00115., 2011.
(DOI: 10.3389/fmicb.2011.00115,   PubMed: 21747811)
48. Masako Nomaguchi and Akio Adachi :
HIV-1 Vpr and G2 cell cycle arrest.,
Future Microbiology, Vol.6, No.4, 375-378, 2011.
(DOI: 10.2217/fmb.11.17,   PubMed: 21526938)
49. Masako Nomaguchi, N. Doi, S. Fujiwara, M. Fujita and Akio Adachi :
Site-defective mutants with distinct ability to down-modulate cell surface CD4 and tetherin,
Frontiers in Microbiology, Vol.1, No.116, 2010.
(DOI: 10.3389/fmicb.2010.00116,   PubMed: 21607084)
50. Akatsuki Saito, Masako Nomaguchi, Sayuki Iijima, Ayumu Kuroishi, Tomoyuki Yoshida, Young-Jung Lee, Toshiyuki Hayakawa, Ken Kono, Emi E. Nakayama, Tatsuo Shioda, Yasuhiro Yasutomi, Akio Adachi, Tetsuro Matano and Hirofumi Akari :
Improved capacity of a monkey-tropic HIV-1 derivative to replicate in cynomolgus monkeys with minimal modifications.,
Microbes and Infection, Vol.13, No.1, 58-64, 2010.
(DOI: 10.1016/j.micinf.2010.10.001,   PubMed: 20955815)
51. Naoya Doi, Sachi Fujiwara, Akio Adachi and Masako Nomaguchi :
Growth ability in various macaque cell lines of HIV-1 with simian cell-tropism.,
The Journal of Medical Investigation : JMI, Vol.57, No.3-4, 284-292, 2010.
(Tokushima University Institutional Repository: 72850,   DOI: 10.2152/jmi.57.284,   PubMed: 20847529,   Elsevier: Scopus)
52. Masako Nomaguchi and Akio Adachi :
Virology as biosystematics: towards understanding the viral infection biology,
Frontiers in Microbiology, Vol.1, No.2, 2010.
(DOI: 10.3389/fmicb.2010.00002,   PubMed: 21747778)
53. Tamiko Nagao, Tomoki Yamashita, Ariko Miyake, Tsuneo Uchiyama, Masako Nomaguchi and Akio Adachi :
Different interaction between HIV-1 Vif and its cellular target proteins APOBEC3G/APOBEC3F.,
The Journal of Medical Investigation : JMI, Vol.57, No.1-2, 89-94, 2010.
(Tokushima University Institutional Repository: 72821,   DOI: 10.2152/jmi.57.89,   PubMed: 20299747)
54. Mikako Fujita, Masami Otsuka, Masako Nomaguchi and Akio Adachi :
Multifaceted activity of HIV Vpr/Vpx proteins: the current view of their virological functions.,
Reviews in Medical Virology, Vol.20, No.2, 68-76, 2010.
(DOI: 10.1002/rmv.636,   PubMed: 20069611)
55. Tomoki Yamashita, Masako Nomaguchi, Ariko Miyake, Tsuneo Uchiyama and Akio Adachi :
Status of APOBEC3G/F in cells and progeny virions modulated by Vif determines HIV-1 infectivity.,
Microbes and Infection, Vol.12, No.2, 166-171, 2009.
(DOI: 10.1016/j.micinf.2009.11.007,   PubMed: 19944180)
56. Abhay Jere, Mikako Fujita, Akio Adachi and Masako Nomaguchi :
Role of HIV-1 Nef protein for virus replication in vitro.,
Microbes and Infection, Vol.12, No.1, 65-70, 2009.
(DOI: 10.1016/j.micinf.2009.09.009,   PubMed: 19770068)
57. Ayumu Kuroishi, Akatsuki Saito, Yasuhiro Shingai, Tatsuo Shioda, Masako Nomaguchi, Akio Adachi, Hirofumi Akari and Emi E. Nakayama :
Modification of a loop sequence between alpha-helices 6 and 7 of virus capsid (CA) protein in a human immunodeficiency virus type 1 (HIV-1) derivative that has simian immunodeficiency virus (SIVmac239) vif and CA alpha-helices 4 and 5 loop improves replication in cynomolgus monkey cells.,
Retrovirology, Vol.6, 70, 2009.
(DOI: 10.1186/1742-4690-6-70,   PubMed: 19650891)
58. Tamiko Nagao, Kazuki Hatcho, Naoya Doi, Sachi Fujiwara, Akio Adachi and Masako Nomaguchi :
Amino acid alterations in Gag that confer the ability to grow in simian cells on HIV-1 are located at a narrow CA region.,
The Journal of Medical Investigation : JMI, Vol.56, No.1-2, 21-25, 2009.
(Tokushima University Institutional Repository: 110880,   DOI: 10.2152/jmi.56.21,   PubMed: 19262010)
59. Kazuya Kamada, Tomoki Yamashita, Kazuki Hatcho, Akio Adachi and Masako Nomaguchi :
Evasion from CypA- and APOBEC-mediated restrictions is insufficient for HIV-1 to efficiently grow in simian cells.,
Microbes and Infection, Vol.11, No.2, 164-171, 2008.
(DOI: 10.1016/j.micinf.2008.11.002,   PubMed: 19056509)
60. Mikako Fujita, Masami Otsuka, Masako Nomaguchi and Akio Adachi :
Functional region mapping of HIV-2 Vpx protein.,
Microbes and Infection, Vol.10, No.12-13, 1387-1392, 2008.
(DOI: 10.1016/j.micinf.2008.08.005,   PubMed: 18771746)
61. Masako Nomaguchi, Mikako Fujita and Akio Adachi :
Role of HIV-1 Vpu protein for virus spread and pathogenesis.,
Microbes and Infection, Vol.10, No.9, 960-967, 2008.
(DOI: 10.1016/j.micinf.2008.07.006,   PubMed: 18672082)
62. Kazuki Hatcho, Kazuya Kamada, Tomoki Yamashita, Akio Adachi and Masako Nomaguchi :
Replication potentials of vif variant viruses generated from monkey cell-tropic HIV-1 derivative clones NL-DT5/NL-DT5R.,
Microbes and Infection, Vol.10, No.10-11, 1218-1222, 2008.
(DOI: 10.1016/j.micinf.2008.06.007,   PubMed: 18617010)
63. Tomoki Yamashita, Kazuya Kamada, Kazuki Hatcho, Akio Adachi and Masako Nomaguchi :
Identification of amino acid residues in HIV-1 Vif critical for binding and exclusion of APOBEC3G/F.,
Microbes and Infection, Vol.10, No.10-11, 1142-1149, 2008.
(DOI: 10.1016/j.micinf.2008.06.003,   PubMed: 18603011)
64. Mikako Fujita, Masami Otsuka, Masami Miyoshi, Boonruang Khamsri, Masako Nomaguchi and Akio Adachi :
Vpx is critical for reverse transcription of the human immunodeficiency virus type 2 genome in macrophages.,
Journal of Virology, Vol.82, No.15, 7752-7756, 2008.
(DOI: 10.1128/JVI.01003-07,   PubMed: 18495778)
65. Masako Nomaguchi, Naoya Doi, Kazuya Kamada and Akio Adachi :
Species barrier of HIV-1 and its jumping by virus engineering.,
Reviews in Medical Virology, Vol.18, No.4, 261-275, 2008.
(DOI: 10.1002/rmv.576,   PubMed: 18386279)
66. Tomoki Yamashita, Naoya Doi, Akio Adachi and Masako Nomaguchi :
Growth ability in simian cells of monkey cell-tropic HIV-1 is greatly affected by downstream region of the vif gene.,
The Journal of Medical Investigation : JMI, Vol.55, No.3-4, 236-240, 2008.
(Tokushima University Institutional Repository: 110865,   DOI: 10.2152/jmi.55.236,   PubMed: 18797137)
67. Tatsuhiko Igarashi, Ranjini Lyengar, Russel A. Byrum, Alicia Buckler-White, Robin L. Dewar, Charles E. Buckler, H. Clifford Lane, Kazuya Kamada, Akio Adachi and Malcolm A. Martin :
Human immunodeficiency virus type 1 derivative with 7% simian immunodeficiency virus genetic content is able to establish infections in pig-tailed macaques,
Journal of Virology, Vol.81, No.20, 11549-11552, 2007.
(DOI: 10.1128/JVI.00960-07,   PubMed: 17670817,   Elsevier: Scopus)
68. Ahmad Piroozmand, Yoshihiko Yamamoto, Boonruang Khamsri, Mikako Fujita, Tsuneo Uchiyama and Akio Adachi :
Generation and characterization of APOBEC3G-positive 293T cells for HIV-1 Vif study,
The Journal of Medical Investigation : JMI, Vol.54, No.1-2, 154-158, 2007.
(Tokushima University Institutional Repository: 111507,   DOI: 10.2152/jmi.54.154,   PubMed: 17380027,   Elsevier: Scopus)
69. Kazuya Kamada, Tatsuhiko Igarashi, Malcolm A. Martin, Boonruang Khamsri, Kazuki Hatcho, Tomoki Yamashita, Mikako Fujita, Tsuneo Uchiyama and Akio Adachi :
Generation of HIV-1 derivatives that productively infect macaque monkey lymphoid cells,
Proceedings of the National Academy of Sciences of the United States of America, Vol.103, No.45, 16959-16964, 2006.
(DOI: 10.1073/pnas.0608289103,   PubMed: 17065315,   Elsevier: Scopus)
70. A. Piroozmand, B. Khamsri, M. Fujita, Akio Adachi and T. Uchiyama :
Morphological study on biologically distinct vpx/vpr mutants of HIV-2,
The Journal of Medical Investigation : JMI, Vol.53, No.3-4, 271-276, 2006.
(Tokushima University Institutional Repository: 110822,   DOI: 10.2152/jmi.53.271,   PubMed: 16953064,   Elsevier: Scopus)
71. K Kamada, Akiko Yoshida, Boonruang Khamsri, A Piroozmand, T Yamashita, Tsuneo Uchiyama, Mikako Fujita and Akio Adachi :
Construction of gag-chimeric viruses between HIV-1 and SIVmac that are capable of productive multi-cycle infection,
Microbes and Infection, Vol.8, No.4, 1075-1081, 2006.
(DOI: 10.1016/j.micinf.2005.11.006,   PubMed: 16520079,   Elsevier: Scopus)
72. Boonruang Khamsri, Fumiko Murao, Akiko Yoshida, Akiko Sakurai, Tsuneo Uchiyama, Hiroki Shirai, Yo Matsuo, Mikako Fujita and Akio Adachi :
Comparative study on the structure and cytopathogenic activity of HIV Vpr/Vpx proteins,
Microbes and Infection, Vol.8, No.1, 10-15, 2006.
(DOI: 10.1016/j.micinf.2005.05.020,   PubMed: 16153874,   Elsevier: Scopus)
73. Hirokazu Miyoshi, 山本 康代 and Akio Adachi :
教育訓練受講時期の教育効果に与える影響と再教育訓練内容の検討,
Japanese Journal of Radiation Safety Management, Vol.4, No.1, 33-38, 2005.
(CiNii: 1390001205398408448)
74. Akiko Yoshida, Ahmad Piroozmand, Akiko Sakurai, Mikako Fujita, Tsuneo Uchiyama, Tooru Kimura, Yoshio Hayashi, Yoshiaki Kiso and Akio Adachi :
Establishment of a biological assay system for human retroviral protease activity,
Microbes and Infection, Vol.7, No.5-6, 820-824, 2005.
(DOI: 10.1016/j.micinf.2005.02.008,   PubMed: 15893491,   Elsevier: Scopus)
75. Huaqing Wang, Akiko Sakurai, Boonruang Khamsri, Tsuneo Uchiyama, Hongxi Gu, Akio Adachi and Mikako Fujita :
Unique characteristics of HIV-1 Vif expression,
Microbes and Infection, Vol.7, No.3, 385-390, 2005.
(DOI: 10.1016/j.micinf.2004.11.010,   PubMed: 15784183,   Elsevier: Scopus)
76. Abhay Jere, Ahmad Piroozmand, Spikanth Tripathy, Ramesh Paranjape, Akiko Sakurai, Mikako Fujita and Akio Adachi :
Generation and characterization of HIV-1 clones chimeric for subtypes B and C nef,
International Journal of Molecular Medicine, Vol.14, No.6, 1087-1090, 2004.
(DOI: 10.3892/ijmm.14.6.1087,   PubMed: 15547679,   Elsevier: Scopus)
77. Tamiko Nagao, Akiko Yoshida, Akiko Sakurai, Ahmad Piroozmand, Abhay Jere, Mikako Fujita, Tsuneo Uchiyama and Akio Adachi :
Determination of HIV-1 infectivity by lymphocytic cell lines with integrated luciferase gene,
International Journal of Molecular Medicine, Vol.14, No.6, 1073-1076, 2004.
(DOI: 10.3892/ijmm.14.6.1073,   PubMed: 15547676,   Elsevier: Scopus)
78. Ahmad Piroozmand, Hajime A Koyama, Yoshiko Shimada, Mikako Fujita, Tsutomu Arakawa and Akio Adachi :
Role of Us3 gene of herpes simplex virus type 1 for resistance to interferon,
International Journal of Molecular Medicine, Vol.14, No.4, 641-645, 2004.
(DOI: 10.3892/ijmm.14.4.641,   PubMed: 15375595,   Elsevier: Scopus)
79. Fumihiro Sugahara, Tsuneo Uchiyama, Hitoshi Watanabe, Yukie Shimazu, Masaru Kuwayama, Yutaka Fujii, Katsuhiro Kiyotani, Akio Adachi, Nobuoki Kohno, Tetsuya Yoshida and Takemasa Sakaguchi :
Paramyxovirus Sendai virus-like particle formation by expression of multiple viral proteins and acceleration of its release by C protein.,
Virology, Vol.325, No.1, 1-10, 2004.
(DOI: 10.1016/j.virol.2004.04.019,   PubMed: 15231380)
80. Akiko Sakurai, Abhay Jere, Akiko Yoshida, Takeshi Yamada, Aikichi Iwamoto, Akio Adachi and Mikako Fujita :
Functional analysis of HIV-1 vif genes derived from Japanese long-term nonprogressors and progressors for AIDS,
Microbes and Infection, Vol.6, No.9, 799-805, 2004.
(DOI: 10.1016/j.micinf.2004.04.005,   PubMed: 15374001,   Elsevier: Scopus)
81. Mikako Fujita, Hirofumi Akari, Akiko Sakurai, Akiko Yoshida, Tomoki Chiba, Keiji Tanaka, Klaus Strebel and Akio Adachi :
Expression of HIV-1 accessory protein Vif is controlled uniquely to be low and optimal by proteasome degradation,
Microbes and Infection, Vol.6, No.9, 791-798, 2004.
(DOI: 10.1016/j.micinf.2004.04.011,   PubMed: 15374000,   Elsevier: Scopus)
82. Hirofumi Akari, Mikako Fujita, Sandra Kao, Mohammad A. Khan, Miranda Shehu-Xhilaga, Akio Adachi and Klaus Strebel :
High Level Expression of Human Immunodeficiency Virus Type-1 Vif Inhibits Viral Infectivity by Modulating Proteolytic Processing of the Gag Precursor at the p2/Nucleocapsid Processing Site,
The Journal of Biological Chemistry, Vol.279, No.13, 12355-12362, 2004.
(DOI: 10.1074/jbc.M312426200,   PubMed: 14722068,   Elsevier: Scopus)
83. Hajime A Koyama, Akio Adachi and Hiroshi Irie :
Physiological significance of apoptosis during animal virus infection,
International Reviews of Immunology, Vol.22, No.5-6, 341-359, 2003.
(DOI: 10.1080/08830180305210,   PubMed: 12959749,   Elsevier: Scopus)
84. Mikako Fujita, Akiko Yoshida, Akiko Sakurai, Junko Tatsuki, Fumiko Ueno, Hirofumi Akari and Akio Adachi :
Susceptibility of HVS-immortalized lymphocytic HSC-F cells to various strains and mutants of HIV/SIV,
International Journal of Molecular Medicine, Vol.11, No.5, 641-644, 2003.
(DOI: 10.3892/ijmm.11.5.641,   PubMed: 12684704,   Elsevier: Scopus)
85. Fumiko Ueno, Hiroshi Shiota, Maki Miyaura, Akiko Yoshida, Akiko Sakurai, Junko Tatsuki, Hajime A Koyama, Hirofumi Akari, Akio Adachi and Mikako Fujita :
Vpx and Vpr proteins of HIV-2 up-regulate the viral infectivity by a distinct mechanism in lymphocytic cells,
Microbes and Infection, Vol.5, No.5, 387-395, 2003.
(DOI: 10.1016/S1286-4579(03)00042-X,   PubMed: 12737994,   Elsevier: Scopus)
86. Hajime A Koyama, Hiroshi Irie, Atsushi Kato, Yoshiyuki Nagai and Akio Adachi :
Virus multiplication and induction of apoptosis by Sendai virus: role of the C proteins,
Microbes and Infection, Vol.5, No.5, 373-378, 2003.
(DOI: 10.1016/S1286-4579(03)00043-1,   PubMed: 12737992,   Elsevier: Scopus)
87. Masataka Nishimura, Michiyuki Maeda, Jun-ichiro Yasunaga, Hideshi Kawakami, Ryuji Kaji, Akio Adachi, Takashi Uchiyama and Masao Matsuoka :
Influence of cytokine and mannose binding protein gene polymorphisms on human t-cell leukemia virus type i (hTLV-i) provirus load in HTLV-I asymptomatic carriers,
Human Immunology, Vol.64, No.4, 453-457, 2003.
(DOI: 10.1016/S0198-8859(02)00829-7,   PubMed: 12651071)
88. Mikako Fujita, Akiko Sakurai, Akiko Yoshida, Maki Miyaura, Hajime A Koyama, Koji Sakai and Akio Adachi :
Amino Acid Residues 88 and 89 in the Central Hydrophilic Region of Human Immunodeficiency Virus Type 1 Vif Are Critical for Viral Infectivity by Enhancing the Steady-State Expression of Vif,
Journal of Virology, Vol.77, No.2, 1626-1632, 2003.
(DOI: 10.1128/JVI.77.2.1626-1632.2003,   PubMed: 12502880,   Elsevier: Scopus)
89. Mikako Fujita, Sora Matsumoto, Akiko Sakurai, Naoya Doi, Maki Miyaura, Akiko Yoshida and Akio Adachi :
Apparent lack of trans-dominant negative effects of various vif mutants on the replication of HIV-1,
Microbes and Infection, Vol.4, No.12, 1203-1207, 2002.
(DOI: 10.1016/S1286-4579(02)01646-5,   PubMed: 12467760,   Elsevier: Scopus)
90. Masataka Nishimura, Masao Matsuoka, Michiyuki Maeda, Ikuko Mizut, Shuji Mita, Makoto Uchino, Makoto Matsui, Yasuo Kuroda, Hideshi Kawakami, Ryuji Kaji, Akio Adachi and Takashi Uchiyama :
Association between interleukin-6 gene polymorphism and human T-Cell leukemia virus type I associated myelopathy,
Human Immunology, Vol.63, No.8, 696-700, 2002.
(DOI: 10.1016/S0198-8859(02)00419-6,   PubMed: 12121679)
91. Hiroko Tomiyama, Hirofumi Akari, Akio Adachi and Masafumi Takiguchi :
Different Effects of Nef-Mediated HLA Class I Down-Regulation on Human Immunodeficiency Virus Type 1-Specific CD8+ T-Cell Cytolytic Activity and Cytokine Production,
Journal of Virology, Vol.76, No.15, 7535-7543, 2002.
(DOI: 10.1128/JVI.76.15.7535-7543.2002,   PubMed: 12097566,   Elsevier: Scopus)
92. Mikako Fujita, Akiko Sakurai, Akiko Yoshida, Sora Matsumoto, Maki Miyaura and Akio Adachi :
Subtle mutations in the cysteine region of HIV-1 Vif drastically alter the viral replication phenotype,
Microbes and Infection, Vol.4, No.6, 621-624, 2002.
(DOI: 10.1016/S1286-4579(02)01580-0,   PubMed: 12048031,   Elsevier: Scopus)
93. Hajime A Koyama, Hiroshi Irie, Fumiko Ueno, Motomi Ogawa, Akio Nomoto and Akio Adachi :
Suppression of apoptotic and necrotic cell death by poliovirus,
The Journal of General Virology, Vol.82, No.Pt 12, 2965-2972, 2001.
(DOI: 10.1099/0022-1317-82-12-2965,   PubMed: 11714972,   Elsevier: Scopus)
94. Akio Adachi, Maki Miyaura, Akiko Sakurai, Akiko Yoshida, Hajime A Koyama and Mikako Fujita :
Growth characteristics of SHIV without the vpu gene,
International Journal of Molecular Medicine, Vol.8, No.6, 641-644, 2001.
(DOI: 10.3892/ijmm.8.6.641,   PubMed: 11712079,   Elsevier: Scopus)
95. Hirofumi Akari, Stephan Bour, Sandra Kao, Akio Adachi and Klaus Strebel :
The Human Immunodeficiency Virus Type 1 Accessory Protein Vpu Induces Apoptosis by Suppressing the Nuclear Factor B dependent Expression of Antiapoptotic Factors,
The Journal of Experimental Medicine, Vol.194, No.9, 1299-1311, 2001.
(DOI: 10.1084/jem.194.9.1299,   PubMed: 11696595,   Elsevier: Scopus)
96. Hajime A Koyama, Motomi Ogawa, Atsushi Kato, Yoshiyuki Nagai and Akio Adachi :
Lack of apoptosis in Sendai virus-infected HEp-2 cells without participation of viral antiapoptosis gene,
Microbes and Infection, Vol.3, No.13, 1115-1121, 2001.
(DOI: 10.1016/S1286-4579(01)01472-1,   PubMed: 11709292,   Elsevier: Scopus)
97. Mikako Fujita, Akiko Sakurai, Naoya Doi, Maki Miyaura, Akiko Yoshida, Koji Sakai and Akio Adachi :
Analysis of the cell-dependent replication potentials of human immunodeficiency virus type 1 vif mutants,
Microbes and Infection, Vol.3, No.13, 1093-1099, 2001.
(DOI: 10.1016/S1286-4579(01)01469-1,   PubMed: 11709289,   Elsevier: Scopus)
98. Mikako Fujita, Akiko Yoshida, Maki Miyaura, Akiko Sakurai, Hirofumi Akari, Hajime A Koyama and Akio Adachi :
Cyclophilin A-Independent Replication of a Human Immunodeficiency Virus Type 1 Isolate Carrying a Small Portion of the Simian Immunodeficiency Virus SIV(MAC) gag Capsid Region,
Journal of Virology, Vol.75, No.21, 10527-10531, 2001.
(DOI: 10.1128/JVI.75.21.10527-10531.2001,   PubMed: 11581426,   Elsevier: Scopus)
99. Y. Isaka, S. Miki, S. Kawauchi, A. Suyama, H. Sugimoto, Akio Adachi, T. Miura, M. Hayami, O. Yoshie, T. Fujiwara and A. Sato :
A single amino acid change at Leu-188 in the reverse transcriptase of HIV-2 and SIV renders them sensitive to non-nucleoside reverse transcriptase inhibitors,
Archives of Virology, Vol.146, No.4, 743-755, 2001.
(DOI: 10.1007/s007050170143,   PubMed: 11402860,   Elsevier: Scopus)
100. Y. Isaka, S. Miki, S. Kawauchi, A. Suyama, H. Sugimoto, Akio Adachi, M. Hayami, O. Yoshie, T. Fujiwara and A. Sato :
Isolation and characterization of simian immunodeficiency virus variants that are resistant to nonnucleoside reverse transcriptase inhibitors,
Archives of Virology, Vol.145, No.12, 2481-2492, 2000.
(DOI: 10.1007/s007050070003,   PubMed: 11205100,   Elsevier: Scopus)
101. Kazuya Hashinaka, Seiichi Hashida, Ichiro Nishikata, Akio Adachi, Shinichi Oka and Eiji Ishikawa :
Recombinant p51 as Antigen in an Immune Complex Transfer Enzyme Immunoassay of Immunoglobulin G Antibody to Human Immunodeficiency Virus Type 1,
Clinical and Diagnostic Laboratory Immunology, Vol.7, No.6, 967-976, 2000.
(DOI: 10.1128/CDLI.7.6.967-976.2000,   PubMed: 11063508,   Elsevier: Scopus)
102. Kyu-Bom Koh, Maki Miyaura, Akiko Yoshida, Akiko Sakurai, Mikako Fujita and Akio Adachi :
Cell-dependent gag mutants of HIV-1 are crucially defective at the stage of uncoating/reverse transcription in non-permissive cells,
Microbes and Infection, Vol.2, No.12, 1419-1423, 2000.
(DOI: 10.1016/S1286-4579(00)01295-8,   PubMed: 11099927,   Elsevier: Scopus)
103. Maki Miyaura, Akiko Yoshida, Akiko Sakurai, Mikako Fujita, Hajime A Koyama and Akio Adachi :
Mutational analysis of HIV-1 gag proteins,
International Journal of Molecular Medicine, Vol.6, No.3, 265-269, 2000.
(PubMed: 10934287,   Elsevier: Scopus)
104. Kazuya Hashinaka, Ichiro Nishikata, Seiichi Hashida, Akio Adachi, Shinichi Oka and Eiji Ishikawa :
Preparations of recombinant HIV-1 p66 antigen to improve the specificity of immune complex transfer enzyme immunoassay of antibody IgG to HIV-1 reverse transcriptase,
Journal of Clinical Laboratory Analysis, Vol.14, No.4, 169-179, 2000.
(DOI: 10.1002/1098-2825(2000)14:4<169::AID-JCLA6>3.0.CO;2-E,   PubMed: 10906770,   Elsevier: Scopus)
105. Hajime A Koyama, Tomoharu Fukumori, Mikako Fujita, Hiroshi Irie and Akio Adachi :
Physiological significance of apoptosis in animal virus infection,
Microbes and Infection, Vol.2, No.9, 1111-1117, 2000.
(DOI: 10.1016/S1286-4579(00)01265-X,   PubMed: 10967291)
106. Hirofumi Akari, Akiko Yoshida, Tomoharu Fukumori and Akio Adachi :
Host cell-dependent replication of HIV-1 mutants with deletions in gp41 cytoplasmic tail region is independent of the function of Vif,
Microbes and Infection, Vol.2, No.9, 1019-1023, 2000.
(DOI: 10.1016/S1286-4579(00)01256-9,   PubMed: 11032465)
107. Akiko Yoshida, Maki Miyaura, Akiko Sakurai, Tomoharu Fukumori, Mikako Fujita, Hirofumi Akari and Akio Adachi :
MHC-I expression in HTLV-1-positive and -negative cells,
International Journal of Molecular Medicine, Vol.6, No.1, 83-86, 2000.
(PubMed: 10851271,   Elsevier: Scopus)
108. Tomoharu Fukumori, Akari Hirofumi, Yoshida Akiko, Mikako Fujita, Koyama AH, Susumu Kagawa and Akio Adachi :
Regulation of cell cycle and apoptosis by human immunodeficiency virus type 1 Vpr.,
Microbes and Infection, Vol.2, No.9, 1011-1017, 2000.
(DOI: 10.1016/S1286-4579(00)01255-7,   PubMed: 10967282,   Elsevier: Scopus)
109. Hirofumi Akari, Tomoharu Fukumori and Akio Adachi :
Cell-dependent requirement of human immunodeficiency virus type 1 gp41 cytoplasmic tail for Env incorporation into virions.,
Journal of Virology, Vol.74, No.10, 4891-4893, 2000.
(DOI: 10.1128/JVI.74.10.4891-4893.2000,   PubMed: 10775630,   Elsevier: Scopus)
110. Hajime A Koyama, Tsutomu Arakawa and Akio Adachi :
Characterization of apoptosis induced by sorbitol: a unique system for the detection of antiapoptotic activities of viruses,
Microbes and Infection, Vol.2, No.6, 599-606, 2000.
(DOI: 10.1016/S1286-4579(00)00366-X,   PubMed: 10884610,   Elsevier: Scopus)
111. Hirofumi Akari, Stefan Arold, Tomoharu Fukumori, Toshiyuki Okazaki, Klaus Strebel and Akio Adachi :
Nef-Induced Major Histocompatibility Complex Class I Down-Regulation Is Functionally Dissociated from Its Virion Incorporation, Enhancement of Viral Infectivity, and CD4 Down-Regulation,
Journal of Virology, Vol.74, No.6, 2907-2912, 2000.
(DOI: 10.1128/JVI.74.6.2907-2912.2000,   PubMed: 10684310,   Elsevier: Scopus)
112. Akiko Yoshida, J Shimomoto, KB Koh, Mikako Fujita and Akio Adachi :
The H9/M8166 tropism of various HIV-1 mutants is determined by distinct cellular factors,
International Journal of Molecular Medicine, Vol.5, No.3, 291-294, 2000.
(DOI: 10.3892/ijmm.5.3.291,   PubMed: 10677572,   Elsevier: Scopus)
113. Hirofumi Akari, Stefan Arold, Tomoharu Fukumori, Toshiyuki Okazaki, Klaus Strebel and Akio Adachi :
Nef-induced major histocompatibility complex class 1 down-regulation is functionally dissociated from its virion incorporation, enhancement of virul infectibity, and CD4 down-regulation.,
Journal of Virology, Vol.74, No.6, 2907-2912, 2000.
114. Yoshitaka Isaka, Akihiko Sato, Shigeru Miki, Shinobu Kawauchi, Hitoshi Sakaida, Toshiyuki Hori, Takashi Uchiyama, Akio Adachi, Masanori Hayami, Tamio Fujiwara and Osamu Yoshie :
Small Amino Acid Changes in the V3 Loop of Human Immunodeficiency Virus Type 2 Determines the Coreceptor Usage for CXCR4 and CCR5,
Virology, Vol.264, No.1, 237-243, 1999.
(DOI: 10.1006/viro.1999.0006,   PubMed: 10544150,   Elsevier: Scopus)
115. Hirofumi Akari, Tsuneo Uchiyama, Tomoharu Fukumori, Shinya Iida, Hajime A Koyama and Akio Adachi :
Pseudotyping human immunodeficiency virus type 1 by vesicular stomatitis virus G protein does not reduce the cell-dependent requirement of Vif for optimal infectivity: functional difference between Vif and Nef,
The Journal of General Virology, Vol.80, No.11, 2945-2949, 1999.
(PubMed: 10580056,   Elsevier: Scopus)
116. Hajime A Koyama, Tsutomu Arakawa and Akio Adachi :
Comparison of an antiviral activity of recombinant consensus interferon with recombinant interferon-α-2b,
Microbes and Infection, Vol.1, No.13, 1073-1077, 1999.
(DOI: 10.1016/S1286-4579(99)00210-5,   PubMed: 10572309,   Elsevier: Scopus)
117. Hirofumi Akari, Tomoharu Fukumori, Shinya Iida and Akio Adachi :
Induction of Apoptosis in Herpesvirus saimiri-Immortalized T Lymphocytes by Blocking Interaction of CD28 with CD80/CD86,
Biochemical and Biophysical Research Communications, Vol.263, No.2, 352-356, 1999.
118. Akio Adachi, Michio Tamaki, Reika Shimano, Ritsuko Inubushi, Takehiro Naito, Kazuko Yoshida, Yoko Oshima, Meiko Kawamura and Hajime A Koyama :
Cell-dependent replication potentials of HIV-1 gag mutants,
Microbes and Infection, Vol.1, No.9, 671-676, 1999.
(DOI: 10.1016/S1286-4579(99)80068-9,   PubMed: 10611744,   Elsevier: Scopus)
119. So Hata, Hajime A Koyama, Hiroshi Shiota, Akio Adachi, Fumi Goshima and Yukihiro Nishiyama :
Antiapoptotic activity of herpes simplex virus type 2: the role of US3 protein kinase gene,
Microbes and Infection, Vol.1, No.8, 601-607, 1999.
(DOI: 10.1016/S1286-4579(99)80059-8,   PubMed: 10611736,   Elsevier: Scopus)
120. Reika Shimano, Ritsuko Inubushi, Yoko Oshima and Akio Adachi :
Inhibition of HIV/SIV Replication by Dominant Negative Gag Mutants,
Virus Genes, Vol.18, No.3, 197-201, 1999.
(DOI: 10.1023/A:1008054111697,   PubMed: 10456787,   Elsevier: Scopus)
121. Hirofumi Akari, Ki-Hoan Nam, Kazuyasu Mori, Isao Otani, Hiroaki Shibata, Akio Adachi, Keiji Terao and Yasuhiro Yoshikawa :
Effects of SIVmac Infection on Peripheral Blood CD4+CD8+T Lymphocytes in Cynomolgus Macaques,
Clinical Immunology, Vol.91, No.3, 321-329, 1999.
(DOI: 10.1006/clim.1999.4700,   PubMed: 10370378,   Elsevier: Scopus)
122. Reika Shimano, Ritsuko Inubushi and Akio Adachi :
Host cell-dependent replication of HIV-1 gag MA, CA, and NC mutants are independent of the functions of Vif and Vpu,
International Journal of Molecular Medicine, Vol.3, No.1, 91-94, 1999.
(DOI: 10.3892/ijmm.3.1.91,   PubMed: 9864392)
123. Kenzo Tokunaga, Kazuyoshi Ikuta, Akio Adachi, Michiyuki Matsuda, Takeshi Kurata and Asato Kojima :
The Cellular Kinase Binding Motifs (PxxP and RR) in Human Immunodeficiency Virus Type 1 Nef Protein Are Dispensable for Producer-Cell-Dependent Enhancement of Viral Entry,
Virology, Vol.257, No.2, 285-289, 1999.
(DOI: 10.1006/viro.1999.9682,   PubMed: 10329538,   Elsevier: Scopus)
124. Ritsuko Inubushi and Akio Adachi :
Cell-dependent function of HIV-1 Vif for virus replication,
International Journal of Molecular Medicine, Vol.3, No.5, 473-476, 1999.
(PubMed: 10202177,   Elsevier: Scopus)
125. Shinya Iida, Tomoharu Fukumori, Yoko Oshima, Hirofumi Akari, Hajime A Koyama and Akio Adachi :
Compatibility of Vpu-like Activity in the Four Groups of Primate Immunodeficiency Viruses,
Virus Genes, Vol.18, No.2, 183-187, 1999.
126. Koji Sakai, Miyuki Horiuchi, Shinya Iida, Tomoharu Fukumori, Hirofumi Akari and Akio Adachi :
Mutational Analysis of Human Immunodeficiency Virus Type 1 Vif Gene,
Virus Genes, Vol.18, No.2, 179-181, 1999.
(PubMed: 10403705)
127. Akio Adachi and Yoko Oshima :
Cell-dependent functional roles of HIV-1 Nef for virus replication,
International Journal of Molecular Medicine, Vol.3, No.4, 427-430, 1999.
128. Akio Adachi, Yoko Oshima and Hajime A Koyama :
Activation of HIV-1 enhancer sequence by vaccinia virus,
International Journal of Molecular Medicine, Vol.3, No.3, 311-313, 1999.
(PubMed: 10028058,   Elsevier: Scopus)
129. Tomoharu Fukumori, Susumu Kagawa, Shinya Iida, Yoko Oshima, Hirofumi Akari, Hajime A Koyama and Akio Adachi :
Rev-dependent expression of three species of HIV-1 mRNAs,
International Journal of Molecular Medicine, Vol.3, No.3, 297-302, 1999.
(PubMed: 10028055)
130. Shinya Iida, Tomoharu Fukumori, Yoko Oshima, Hajime A Koyama and Akio Adachi :
Growth characteristics of T-cell tropic HIV-1 vpu gene mutants in human peripheral blood mononuclear cells,
The Journal of Medical Investigation : JMI, Vol.46, No.1-2, 43-47, 1999.
(Tokushima University Institutional Repository: 83261,   PubMed: 10408156)
131. Akio Adachi, Shinya Iida, Tomoharu Fukumori, Michio Tamaki, Ritsuko Inubushi, Reika Shimano, Yoko Oshima, Hirofumi Akari and Hajime A Koyama :
Exchangeability of accessory Vif and Vpu proteins between various HIV/SIVs,
International Journal of Molecular Medicine, Vol.3, No.2, 193-197, 1999.
132. Setsuko Ishikawa, Seiichi Hashida, Kazuya Hashinaka, Akio Adachi, Shinichi Oka and Eiji Ishikawa :
Rapid formation of the immune complexes on solid phase in the immune complex transfer enzyme immunoassay for HIV-1 p24 antigen and antibody IgGs to HIV-1,
Journal of Clinical Laboratory Analysis, Vol.12, No.4, 227-237, 1998.
(DOI: 10.1002/(SICI)1098-2825(1998)12:4<227::AID-JCLA7>3.0.CO;2-4,   PubMed: 9671175,   Elsevier: Scopus)
133. Setsuko Ishikawa, Seiichi Hashida, Kazuya Hashinaka, Akio Adachi, Shinichi Oka and Eiji Ishikawa :
Ultrasensitive and rapid enzyme immunoassay (thin aqueous layer immune complex transfer enzyme immunoassay) for antibody IgG to HIV-1 p17 antigen,
Journal of Clinical Laboratory Analysis, Vol.12, No.3, 179-189, 1998.
(DOI: 10.1002/(SICI)1098-2825(1998)12:3<179::AID-JCLA9>3.0.CO;2-4,   PubMed: 9591706,   Elsevier: Scopus)
134. Hajime A Koyama, Hirofumi Akari, Akio Adachi, Fumi Goshima and Yukihiro Nishiyama :
Induction of apoptosis in HEp-2 cells by infection with herpes simplex virus type 2,
Archives of Virology, Vol.143, No.12, 2435-2441, 1998.
(DOI: 10.1007/s007050050473,   PubMed: 9930199,   Elsevier: Scopus)
135. Reika Shimano, Ritsuko Inubushi, Michio Tamaki, Hirofumi Akari, Hajime A Koyama and Akio Adachi :
The non-env tropism of HIV/SIV,
International Journal of Molecular Medicine, Vol.2, No.5, 541-544, 1998.
(DOI: 10.3892/ijmm.2.5.541,   PubMed: 9858649)
136. Ritsuko Inubushi, Michio Tamaki, Reika Shimano, Hajime A Koyama, hirofumi Akari and Akio Adachi :
Functional roles of HIV accessory proteins for viral replication,
International Journal of Molecular Medicine, Vol.2, No.4, 429-433, 1998.
(PubMed: 9857229,   Elsevier: Scopus)
137. Kenzo Tokunaga, Asato Kojima, Takeshi Kurata, Kazuyoshi Ikuta, Hirofumi Akari, Hajime A Koyama, Meiko Kawamura, Ritsuko Inubushi, Reika Shimano and Akio Adachi :
Enhancement of human immunodeficiency virus type 1 infectivity by Nef is producer cell-dependent,
The Journal of General Virology, Vol.79, No.10, 2447-2453, 1998.
(DOI: 10.1099/0022-1317-79-10-2447,   PubMed: 9780050,   Elsevier: Scopus)
138. Kenzo Tokunaga, Asato Kojima, Takeshi Kurata, Kazuyoshi Ikuta, Ritsuko Inubushi, Reika Shimano, Meiko Kawamura, Hirofumi Akari, Hajime A Koyama and Akio Adachi :
Producer Cell-Dependent Requirement of the Nef Protein for Efficient Entry of HIV-1 into Cells,
Biochemical and Biophysical Research Communications, Vol.250, No.3, 565-568, 1998.
(DOI: 10.1006/bbrc.1998.9346,   PubMed: 9784383,   Elsevier: Scopus)
139. Ritsuko Inubushi, Reika Shimano, Yoko Oshima, Kazuko Yoshida, Meiko Kawamura and Akio Adachi :
Suppression of HIV replication by dominant negative mutants of HIV-1,
International Journal of Molecular Medicine, Vol.2, No.3, 325-330, 1998.
(PubMed: 9855705,   Elsevier: Scopus)
140. Tomoharu Fukumori, Hirofumi Akari, Shinya Iida, So Hata, Susumu Kagawa, Yoko Aida, Hajime A Koyama and Akio Adachi :
The HIV-1 Vpr displays strong anti-apoptotic activity,
FEBS Letters, Vol.432, No.1-2, 17-20, 1998.
(DOI: 10.1016/S0014-5793(98)00824-2,   PubMed: 9710242)
141. Meiko Kawamura, Reika Shimano, Ritsuko Inubushi, Hirofumi Akari and Akio Adachi :
Early Function of HIV-1 Gag Proteins Is Cell-Dependent,
Biochemical and Biophysical Research Communications, Vol.248, No.3, 899-903, 1998.
(DOI: 10.1006/bbrc.1998.9065,   PubMed: 9704024,   Elsevier: Scopus)
142. Reika Shimano, Ritsuko Inubushi, Tomoharu Fukumori, Michio Tamaki, Yoko Oshima, Meiko Kawamura and Akio Adachi :
Suppression of HIV-2 Replication by HIV-1gagMutants,
Biochemical and Biophysical Research Communications, Vol.248, No.2, 418-421, 1998.
(DOI: 10.1006/bbrc.1998.8975,   PubMed: 9675152,   Elsevier: Scopus)
143. Ritsuko Inubushi, Reika Shimano, Yoko Oshima and Akio Adachi :
The Potential of Various HIV-1 Mutants to Inhibit the Replication of Wild-Type Virus,
Biochemical and Biophysical Research Communications, Vol.247, No.2, 349-352, 1998.
(DOI: 10.1006/bbrc.1998.8790,   PubMed: 9642129,   Elsevier: Scopus)
144. Hirofumi Akari, Kazuyasu Mori, Isao Otani, Keiji Terao, Fumiko Ono, Akio Adachi and Yasuhiro Yoshikawa :
Induction of MHC-II DR expression on circulating CD8+ lymphocytes in macaques infected with SIVmac239 nef-open but not with its nef-deletion mutant,
AIDS Research and Human Retroviruses, Vol.14, No.7, 619-625, 1998.
(DOI: 10.1089/aid.1998.14.619,   PubMed: 9591716,   Elsevier: Scopus)
145. Hajime A Koyama, Tsutomu Arakawa and Akio Adachi :
Acceleration of virus-induced apoptosis by tumor necrosis factor,
FEBS Letters, Vol.426, No.2, 179-182, 1998.
(DOI: 10.1016/S0014-5793(98)00338-X,   PubMed: 9599003,   Elsevier: Scopus)
146. Hirofumi Akari, Hideo Yagita, Tadashi Nishida, Kenji Nakamaru, Yasuhiro Yoshikawa and Akio Adachi :
Selective induction of β7 integrin expression on lymphocytes undergoing apoptosis in lymphoid tissues,
Biochemical and Biophysical Research Communications, Vol.244, No.2, 578-582, 1998.
(DOI: 10.1006/bbrc.1998.8308,   PubMed: 9514955,   Elsevier: Scopus)
147. Hirofumi Akari, Fumiko Ono, Ippei Sakakibara, Hikaru Takahashi, Yuichi Murayama, Akio Hiyaoka, Keiji Terao, Isao Otani, Ryozaburo Mukai, Akio Adachi and Yasuhiro Yoshikawa :
Simian T cell leukemia virus type I-induced malignant adult T cell leukemia-like disease in a naturally infected African green monkey: implication of CD8+ T cell leukemia,
AIDS Research and Human Retroviruses, Vol.14, No.4, 367-371, 1998.
(DOI: 10.1089/aid.1998.14.367,   PubMed: 9519898)
148. Meiko Kawamura, Reika Shimano, Takashi Ogasawara, Ritsuko Inubushi, Kazushi Amano, Hirofumi Akari and Akio Adachi :
Mapping the genetic determinants of human immunodeficiency virus type 2 for cell tropism and replication efficiency,
Archives of Virology, Vol.143, No.3, 513-521, 1998.
(DOI: 10.1007/s007050050307,   PubMed: 9572552,   Elsevier: Scopus)
149. Hirofumi Akari, Yoshihiko Yamamoto, Hiroko Hiwada, Yasuyoshi Saito, Noriyasu Takayanagi, Hajime A Koyama and Akio Adachi :
Suppression of HIV-1 replication in peripheral blood mononuclear cells by fasudil,
The Journal of Medical Investigation : JMI, Vol.44, No.3-4, 211-214, 1998.
(Tokushima University Institutional Repository: 110669,   PubMed: 9597811,   Elsevier: Scopus)
150. Reika Shimano, Shinya Iida, Tomoharu Fukumori, Yoshihiko Yamamoto, Meiko Kawamura, Rika A. Furuta and Akio Adachi :
Inhibition of HIV Replication by Capsid Mutant C6b,
Biochemical and Biophysical Research Communications, Vol.242, No.2, 313-316, 1998.
(DOI: 10.1006/bbrc.1997.7963,   PubMed: 9446791,   Elsevier: Scopus)
151. Reika Shimano, Ritsuko Inubushi, Kazushi Amano, Takashi Ogasawara, Hirofumi Akari, Hajime A Koyama, Meiko Kawamura and Akio Adachi :
Complete Inhibition of SIVmac Replication by its Capsid Mutants,
Virus Genes, Vol.17, No.1, 43-48, 1998.
152. Reika Shimano, Ritsuko Inubushi, Kazushi Amano, Takashi Ogasawara and Akio Adachi :
Gag Pol Region Determines the Tropism of SIVagm for Human Cells,
Virus Genes, Vol.16, No.2, 137-139, 1998.
(DOI: 10.1023/A:1007971620863,   PubMed: 9608656,   Elsevier: Scopus)
153. Hirofumi AKARI, Keiji TERAO, Ki-Hoan NAM, Akio Adachi and Yasuhiro YOSHIKAWA :
Comparative Analysis of Human and Macaque Monkey CD4: Differences in Formaldehyde Lability and Conformation,
Experimental Animals, Vol.47, No.1, 23-27, 1998.
(DOI: 10.1538/expanim.47.23,   PubMed: 9498109,   Elsevier: Scopus)
154. Meiko Kawamura, Reika Shimano, Ritsuko Inubushi, Kazushi Amano, Takashi Ogasawara, Hirofumi Akari and Akio Adachi :
Functional Domain Mapping of HIV-1 Gag Proteins,
Biochemical and Biophysical Research Communications, Vol.241, No.2, 317-320, 1997.
(DOI: 10.1006/bbrc.1997.7814,   PubMed: 9425269,   Elsevier: Scopus)
155. Hajime A Koyama and Akio Adachi :
Induction of apoptosis by herpes simplex virus type 1,
The Journal of General Virology, Vol.78, 2909-2912, 1997.
(DOI: 10.1099/0022-1317-78-11-2909,   PubMed: 9367378,   Elsevier: Scopus)
156. Rika A. Furuta, Reika Shimano, Takashi Ogasawara, Ritsuko Inubushi, Kazushi Amano, Hirofumi Akari, Masakazu Hatanaka, Meiko Kawamura and Akio Adachi :
HIV-1 capsid mutants inhibit the replication of wild-type virus at both early and late infection phases,
FEBS Letters, Vol.415, No.2, 231-234, 1997.
(DOI: 10.1016/S0014-5793(97)01132-0,   PubMed: 9351002,   Elsevier: Scopus)
157. Meiko Kawamura, Reika Shimano, Ritsuko Inubushi, Kazushi Amano, Takashi Ogasawara, Hirofumi Akari and Akio Adachi :
Cleavage of Gag precursor is required for early replication phase of HIV-1,
FEBS Letters, Vol.415, No.2, 227-230, 1997.
(DOI: 10.1016/S0014-5793(97)01131-9,   PubMed: 9351001,   Elsevier: Scopus)
158. Tatsuhiko Igarashi, Yasushi Ami, Hiroshi Yamamoto, Riri Shibata, Takeo Kuwata, Ryozaburo Mukai, Katsuaki Shinohara, Toshihiko Komatsu, Akio Adachi and Masanori Hayami :
Protection of monkeys vaccinated with vpr- and/or nef-defective simian immunodeficiency virus strain mac/human immunodeficiency virus type 1 chimeric viruses: a potential candidate live-attenuated human AIDS vaccine,
The Journal of General Virology, Vol.78, No.Pt5, 985-989, 1997.
(DOI: 10.1099/0022-1317-78-5-985,   PubMed: 9152414,   Elsevier: Scopus)
159. Saburo Sone, Yoshihiko Yamamoto, Akio Adachi, Jin Asano, Shinya Iida and Yasuyoshi Saito :
Functional Analysis of vif Genes Derived from Various Primate Immunodeficiency Viruses,
Virus Genes, Vol.14, No.3, 195-200, 1997.
(DOI: 10.1023/A:1007931826241,   PubMed: 9311564,   Elsevier: Scopus)
160. Kyoko Higo, Yoshinao Kubo, Yasumasa Iwatani, Takeshi Ono, Michiyuki Maeda, Horoshi Hiai, Tohru Masuda, Kagemasa Kuribayashi, Fengmin Zhang, Ta Yar Lamin, Akio Adachi and Akinori Ishimoto :
Susceptibility of nude mice carrying the Fv-4 gene to Friend murine leukemia virus infection,
Journal of Virology, Vol.71, No.1, 750-754, 1997.
(PubMed: 8985411,   Elsevier: Scopus)
161. Kaori Otake, Yoichi Fujii, Masato Tashiro, Akio Adachi and Junzoh Kitoh :
Epitope mapping of murine monoclonal antibodies against human immunodeficiency virus type 1 Nef,
Experimental Animals, Vol.46, No.1, 53-58, 1997.
(DOI: 10.1538/expanim.46.53,   PubMed: 9027472,   Elsevier: Scopus)
162. Kenzo Tokunaga, A Ishimoto, K Ikuta and Akio Adachi :
Growth ability of auxiliary gene mutants of human immunodeficiency virus types 1 and 2 in unstimulated peripheral blood mononuclear cells,
Archives of Virology, Vol.142, No.1, 177-181, 1997.
(DOI: 10.1007/s007050050068,   PubMed: 9155882,   Elsevier: Scopus)
163. Yoichi Fujii, Kaori Otake, Masato Tashiro and Akio Adachi :
In vitro cytocidal effects of human immunodeficiency virus type 1 Nef on unprimed human CD4+ T cells without MHC restriction,
The Journal of General Virology, Vol.77, No.12, 2943-2951, 1996.
(DOI: 10.1099/0022-1317-77-12-2943,   PubMed: 9000084,   Elsevier: Scopus)
164. Yoichi Fujii, Kaori Otake, Yoshikazu Fujita, Naoki Yamamoto, Yoshiyuki Nagai, Masato Tashiro and Akio Adachi :
Clustered localization of oligomeric Nef protein of human immunodeficiency virus type 1 on the cell surface,
FEBS Letters, Vol.395, No.2-3, 257-261, 1996.
(DOI: 10.1016/0014-5793(96)01048-4,   PubMed: 8898107,   Elsevier: Scopus)
165. Yoichi Fujii, Kaori Otake, Masato Tashiro and Akio Adachi :
Human immunodeficiency virus type 1 Nef protein on the cell surface is cytocidal for human CD4+ T cells,
FEBS Letters, Vol.393, No.1, 105-108, 1996.
(DOI: 10.1016/0014-5793(96)00862-9,   PubMed: 8804435,   Elsevier: Scopus)
166. Yoichi Fujii, Kaori Otake, Masato Tashiro and Akio Adachi :
Soluble Nef antigen of HIV-1 is cytotoxic for human CD4+ T cells,
FEBS Letters, Vol.393, No.1, 93-96, 1996.
(DOI: 10.1016/0014-5793(96)00859-9,   PubMed: 8804432,   Elsevier: Scopus)
167. Yoshinao Kubo, Kazuhiro Kakimi, Kyoko Higo, Hirohiko Kobayashi, Takeshi Ono, Yuko Iwama, Kagemasa Kuribayashi, Hiroshi Hiai, Akio Adachi and Akinori Ishimoto :
Possible origin of murine AIDS (MAIDS) virus: conversion of an endogenous retroviral p12gag sequence to a MAIDS-inducing sequence by frameshift mutations,
Journal of Virology, Vol.70, No.9, 6405-6409, 1996.
(PubMed: 8709271,   Elsevier: Scopus)
168. Tatsuhiko Igarashi, Takeo Kuwata, Jun Takehisa, Kentaro Ibuki, Riri Shibata, Ryozaburo Mukai, Toshihiko Komatsu, Akio Adachi, Eiji Ido and Masanori Hayami :
Genomic and biological alteration of a human immunodeficiency virus type 1 (HIV-1)-simian immunodeficiency virus strain mac chimera with HIV-1 Env recovered from a long-term carrier monkey,
The Journal of General Virology, Vol.77, No.8, 1649-1658, 1996.
(DOI: 10.1099/0022-1317-77-8-1649,   PubMed: 8760411,   Elsevier: Scopus)
169. Akihiko Sato, Jun Yoshimoto, Yoshitaka Isaka, Shigeru Miki, Akemi Suyama, Akio Adachi, Masanori Hayami, Tamio Fujiwara and Osamu Yoshie :
Evidence for direct association of Vpr and matrix protein p17 within the HIV-1 virion,
Virology, Vol.220, No.1, 208-212, 1996.
(DOI: 10.1006/viro.1996.0302,   PubMed: 8659115,   Elsevier: Scopus)
170. T. Miura, Riri Shibata, Akio Adachi, T. Kuwata, J. Chen, M Jin, E. Ido and Masanori Hayami :
Genetic complementation between replication-defective mutants of HIV-1 and SIVagm,
Archives of Virology, Vol.141, No.1, 31-41, 1996.
(PubMed: 8629949,   Elsevier: Scopus)
171. Junichi Sakuragi, Sayuri Sakuragi, Shigeharu Ueda and Akio Adachi :
Functional analysis of simian immunodeficiency virus SIVagm long terminal repeat,
Virus Genes, Vol.12, No.1, 21-25, 1996.
(PubMed: 8879117,   Elsevier: Scopus)
172. S. Sakuragi, J. Sakuragi and Akio Adachi :
Both SU and TM Env proteins are responsible for monkey cell tropism of simian immunodeficiency virus SIVmac,
Archives of Virology, Vol.140, No.12, 2255-2260, 1995.
(DOI: 10.1007/BF01323244,   PubMed: 8572945,   Elsevier: Scopus)
173. Akihiko Sato, Yoshitaka Isaka, Makoto Kodama, Jun Yoshimoto, Shinobu Kawauchi, Takeo Kuwata, Akio Adachi, Masanori Hayami, Osamu Yoshie and Tamio Fujiwara :
Targeting of chrolamphenicol acetyltransferase to human immunodeficiency virus particles via Vpr and Vpx,
Microbiology and Immunology, Vol.39, No.12, 1015-1019, 1995.
(DOI: 10.1111/j.1348-0421.1995.tb03293.x,   PubMed: 8789063,   Elsevier: Scopus)
174. Riri Shibata, Hiroyuki Sakai, Meiko Kawamura, Kenzo Tokunaga and Akio Adachi :
Early replication block of human immunodeficiency virus type 1 in monkey cells,
The Journal of General Virology, Vol.76, No.11, 2723-2730, 1995.
(DOI: 10.1099/0022-1317-76-11-2723,   PubMed: 7595379,   Elsevier: Scopus)
175. Hiroyuki Sakai, Kenzo Tokunaga, Meiko Kawamura and Akio Adachi :
Function of human immunodeficiency virus type 1 Vpu protein in various cell types,
The Journal of General Virology, Vol.76, No.11, 2717-2722, 1995.
(DOI: 10.1099/0022-1317-76-11-2717,   PubMed: 7595378,   Elsevier: Scopus)
176. Jun-ichi Sakuragi, Hiroyuki Sakai, Meiko Kawamura, Kenzo Tokunaga, Shigeharu Ueda and Akio Adachi :
Generation and characterization of a host cell-dependent gag gene mutant of human immunodeficiency virus type 1,
Virology, Vol.212, No.1, 251-254, 1995.
(DOI: 10.1006/viro.1995.1478,   PubMed: 7676640,   Elsevier: Scopus)
177. Hiroyuki Sakai, Rika A. Furuta, Kenzo Tokunaga, Meiko Kawamura, Masakazu Hatanaka and Akio Adachi :
Rev-dependency of expression of human immunodeficiency virus type 1 gag and env genes,
FEBS Letters, Vol.365, No.2-3, 141-145, 1995.
(DOI: 10.1016/0014-5793(95)00444-E,   PubMed: 7540150,   Elsevier: Scopus)
178. Jun Katahira, Toshimasa Ishizaki, Hiroyuki Sakai, Akio Adachi, Kazuhiko Yamamoto and Hisatoshi Shida :
Effects of translation initiation factor eIF-5A on the functioning of human T-cell leukemia virus type I Rex and human immunodeficiency virus Rev inhibited trans dominantly by a Rex mutant deficient in RNA binding,
Journal of Virology, Vol.69, No.5, 3125-3133, 1995.
(PubMed: 7707541,   Elsevier: Scopus)
179. Akio Adachi, Hiroyuki Sakai, Kenzo Tokunaga and Meiko Kawamura :
Functional analysis of human spuma retrovirus genome,
Virus Genes, Vol.11, No.1, 15-20, 1995.
(DOI: 10.1007/BF01701657,   PubMed: 8808330,   Elsevier: Scopus)
180. Rika A Furuta, Hiroyuki Sakai, Meiko Kawamura, Kenzo Tokunaga, Masakazu Hatanaka and Akio Adachi :
Functionality of chimeric Rev proteins of HIV/SIV,
Virus Genes, Vol.11, No.1, 11-14, 1995.
(DOI: 10.1007/BF01701656,   PubMed: 8808329,   Elsevier: Scopus)
181. Meiko Kawamura, Hiroyuki Sakai and Akio Adachi :
Human imunodeficiency virus Vpx is required for the early phase of replication in peripheral blood mononuclear cells,
Microbiology and Immunology, Vol.38, No.11, 871-878, 1994.
(DOI: 10.1111/j.1348-0421.1994.tb02140.x,   PubMed: 7898386)
182. Meiko Kawamura, T Ishizaki, A Ishimoto, T Shioda, T Kitamura and Akio Adachi :
Growth ability of human immunodeficiency virus type 1 auxiliary gene mutants in primary blood macrophage cultures,
The Journal of General Virology, Vol.75, No.9, 2427-2431, 1994.
(DOI: 10.1099/0022-1317-75-9-2427,   PubMed: 8077944,   Elsevier: Scopus)
183. Tatsuhiko Igarashi, Riri Shibata, Futoshi Hasebe, Yasushi Ami, Katsuaki Shinohara, Toshihiko Komatsu, Christiane Stahl-Henning, Harald Petry, Gerhard Hunsmann, Takeo Kuwata, Minghao Jin, Akio Adachi, Takashi Kurimura, Mineyuki Okada, Tomoyuki Miura and Masanori Hayami :
Persistent infection with SIVmac chimeric virus having tat, rev, vpu, env, and nef of HIV-1 in macaque monkeys,
AIDS Research and Human Retroviruses, Vol.10, No.8, 1021-1029, 1994.
(DOI: 10.1089/aid.1994.10.1021,   PubMed: 7811533,   Elsevier: Scopus)
184. Yoshiaki Nakagawa, Kazuhiro Kakimi, Ling Wang, Yoshinao Kubo, Kyoko Higo, Toru Masuda, Kagemasa Kuribayashi, Michihiro Iwashiro, Yosuke Komatz, Toshiyasu Hirama, Akio Adachi and Akinori Ishimoto :
Inhibition of murine AIDS(MAIDS) development by the transplantation of bone marrow cells carrying the Fv-4 resistant gene to MAIDS virus-infected mice,
Journal of Virology, Vol.68, No.3, 1438-1441, 1994.
185. Keizo Tomonaga, S Y Shin, M Fukasawa, Takayuki Miyazawa, Akio Adachi and Takeshi Mikami :
Feline immunodeficiency virus gene expression: analysis of the RNA splicing pattern and monocistronic rev mRNA,
The Journal of General Virology, Vol.74, No.11, 2409-2417, 1993.
(DOI: 10.1099/0022-1317-74-11-2409,   PubMed: 8245856,   Elsevier: Scopus)
186. Keizo Tomonaga, Takayuki Miyazawa, Juni-chi Sakuragi, Takeshi Mori, Akio Adachi and Takeshi Mikami :
The feline immunodeficiency virus ORF-A gene facilitates efficient viral replication in established T-cell lines and peripheral blood lymphocytes,
Journal of Virology, Vol.67, No.10, 5889-5895, 1993.
(PubMed: 7690413,   Elsevier: Scopus)
187. Takayuki Miyazawa, M Kohmoto, Y Kawaguchi, Keizo Tomonaga, T Toyosaki, K Ikuta, Akio Adachi and Takeshi Mikami :
The AP-1 binding site in the feline immunodeficiency virus long terminal repeat is not required for virus replication in feline T lymphocytes,
The Journal of General Virology, Vol.74, No.8, 1573-1580, 1993.
(DOI: 10.1099/0022-1317-74-8-1573,   PubMed: 8393913,   Elsevier: Scopus)
188. Hiroyuki Sakai, Jun-ichi Sakuragi, Sayuri Sakuragi, Meiko Kawamura and Akio Adachi :
Compatibility of tat and rev transactivators in the primate lentiviruses,
Archives of Virology, Vol.129, No.1-4, 1-10, 1993.
(DOI: 10.1007/BF01316880,   PubMed: 8385908,   Elsevier: Scopus)
189. Hiroyuki Sakai, Riri Shibata, Jun-ichi Sakuragi, Sayuri Sakuragi, Meiko Kawamura and Akio Adachi :
Cell-dependent requirement of human immunodeficiency virus type 1 Vif protein for maturation of virus particles,
Journal of Virology, Vol.67, No.3, 1663-1666, 1993.
190. Hiroyuki Sakai, Meiko Kawamura, Jun-ichi Sakuragi, Sayuri Sakuragi, Riri Shibata, Akinori Ishimoto, Nobumi Ono, Sigeharu Ueda and Akio Adachi :
Integration is essential for efficient gene expression of human immunodeficiency virus type 1,
Journal of Virology, Vol.67, No.3, 1169-1174, 1993.
(PubMed: 8437208,   Elsevier: Scopus)
191. H. Sakai, S. Sakuragi, J. Sakuragi, M. Kawamura, R. Shibata and Akio Adachi :
Sequences responsible for efficient replication of simian immunodeficiency virus SIVmnd in cells of the monocyte/macrophage lineage,
The Journal of General Virology, Vol.73, No.11, 2989-2993, 1992.
(DOI: 10.1099/0022-1317-73-11-2989,   PubMed: 1431813,   Elsevier: Scopus)
192. S. Sakuragi, R. Shibata, R. Mukai, T. Komatsu, M. Fukasawa, H. Sakai, J. Sakuragi, M. Kawamura, K. Ibuki, M. Hayami and Akio Adachi :
Infection of macaque monkeys with a chimeric human and simian immunodeficiency virus,
The Journal of General Virology, Vol.73, No.Pt11, 2983-2987, 1992.
(DOI: 10.1099/0022-1317-73-11-2983,   PubMed: 1279105,   Elsevier: Scopus)
193. Keizo Tomonaga, Junzo Norimine, Yeon-Sil Shin, Masashi Fukasawa, Takayuki Miyazawa, Akio Adachi, Tomoko Toyosaki, Yasushi Kawaguchi, Chieko Kai and Takeshi Mikami :
Identification of a feline immunodeficiency virus gene which is essential for cell-free virus infectivity,
Journal of Virology, Vol.66, No.10, 6181-6185, 1992.
(PubMed: 1382146,   Elsevier: Scopus)
194. Jun-ichi Sakuragi, Hiroyuki Sakai, Sayuri Sakuragi, Riri Shibata, Simon Wain-Hobson, Masanori Hayami and Akio Adachi :
Functional classification of simian immunodeficiency virus isolated from a chimpanzee by transactivators,
Virology, Vol.189, No.1, 354-358, 1992.
(DOI: 10.1016/0042-6822(92)90715-2,   PubMed: 1604820)
195. Hiroyuki Sakai, Jun-Ichi Sakuragi, Sayuri Sakuragi, Riri Shibata and Akio Adachi :
Functional analysis of biologically distinct genetic variants of simian immunodeficiency virus isolated from a mandrill,
Virology, Vol.189, No.1, 161-166, 1992.
(DOI: 10.1016/0042-6822(92)90691-H,   PubMed: 1604807,   Elsevier: Scopus)
196. T. Miyazawa, Y. Kawaguchi, M. Kohmoto, J. Sakuragi, Akio Adachi, M. Fukasawa and T. Mikami :
Production of feline immunodeficiency virus in feline and non-feline non-lymphoid cell lines by transfection of an infectious molecular clone,
The Journal of General Virology, Vol.73, No.Pt 6, 1543-1546, 1992.
(DOI: 10.1099/0022-1317-73-6-1543,   PubMed: 1318947,   Elsevier: Scopus)
197. H. Sakai, J. Sakuragi, S. Sakuragi, R. Shibata, M. Hayami, A. Ishimoto and Akio Adachi :
Genetic characterization of simian immunodeficiency virus isolated from an African mandrill,
Archives of Virology, Vol.125, No.1-4, 1-14, 1992.
(PubMed: 1642547)
198. Jun-Ichi Sakuragi, Masashi Fukasawa, Riri Shibata, Hiroyuki Sakai, Meiko Kawamura, Hirofumi Akari, Takahiro Kiyomasu, Akinori Ishimoto, Masanori Hayami and Akio Adachi :
Functional analysis of long terminal repeats derived from four strains of simian immunodeficiency virus SIVagm in relation to other primate lentiviruses,
Virology, Vol.185, No.1, 455-459, 1991.
(DOI: 10.1016/0042-6822(91)90798-G,   PubMed: 1656599,   Elsevier: Scopus)
199. Hiroyuki Sakai, Riri Shibata, Jun-Ichi Sakuragi, Takahiro Kiyomasu, Meiko Kawamura, Masanori Hayami, Akinori Ishimoto and Akio Adachi :
Compatibility of rev gene activity in the four groups of primate lentiviruses,
Virology, Vol.184, No.2, 513-520, 1991.
(DOI: 10.1016/0042-6822(91)90421-7,   PubMed: 1716025,   Elsevier: Scopus)
200. Takahiro Kiyomasu, Takayuki Miyazawa, Tetsuya Furuya, Riri Shibata, Hiroyuki Sakai, Jun-ichi Sakuragi, Masashi Fukasawa, Noboru Maki, Akira Hasegawa, Takeshi Mikami and Akio Adachi :
Identification of the feline immunodeficiency virus rev gene activity,
Journal of Virology, Vol.65, No.8, 4539-4542, 1991.
(PubMed: 1649349)
201. Riri Shibata, Meiko Kawamura, Hiroyuki Sakai, Masanori Hayami, Akinori Ishimoto and Akio Adachi :
Generation of a chimeric human and simian immunodeficiency virus infectious to monkey peripheral blood mononuclear cells,
Journal of Virology, Vol.65, No.7, 3514-3520, 1991.
(PubMed: 2041078)
202. Akio Adachi, N. Ono, H. Sakai, R. Shibata, K. Ogawa, T. Kiyomasu, H. Masuike and S. Ueda :
Generation and characterization of the human immunodeficiency virus type 1 mutants,
Archives of Virology, Vol.117, No.1-2, 45-58, 1991.
(PubMed: 1706590)
203. Y. Nishino, M. Kishi, M. Sumiya, K. Ogawa, Akio Adachi, K. Maotani-Imai, S. Kato, K. Hirai and K. Ikuta :
Human immunodeficiency virus type 1 vif, vpr and vpu mutants can produce persistently infected cells,
Archives of Virology, Vol.120, No.3-4, 181-192, 1991.
(PubMed: 1835572)
204. Riri Shibata, Hiroyuki Sakai, Takahiro Kiyomasu, Akinori Ishimoto, Masanori Hayami and Akio Adachi :
Generation and characterization of infectious chimeric clones between human immunodeficiency virus type 1 and simian immunodeficiency virus from an African green monkey,
Journal of Virology, Vol.64, No.12, 5861-5868, 1990.
(PubMed: 1700827)
205. Hiriyuki Sakai, Haruhiko Siomi, Hisatoshi Shida, Riri Shibata, Takahiro Kiyomasu and Akio Adachi :
Functional comparison of transactivation by human retrovirus rev and rex genes,
Journal of Virology, Vol.64, No.12, 5833-5839, 1990.
(PubMed: 1700826,   Elsevier: Scopus)
206. Akihiko Sato, Hisanaga Igarashi, Akio Adachi and Masanori Hayami :
Identification and localization of the vpr gene product of human immunodeficiency virus type 1,
Virus Genes, Vol.4, No.4, 303-312, 1990.
(PubMed: 2149621,   Elsevier: Scopus)
207. Kazuhiro Kakimi, Yoshiko Kishida, Ikuko Higuchi, Takahiro Kiyomasu, Hiroyuki Sakai, Riri Shibata, Shin-ichiro Yanagawa, Akio Adachi and Akinori Ishimoto :
Fv-1 restriction of endogenous feline C-type RD114 virus genome phenotypically mixed with ecotropic murine leukemia viruses,
Japanese Journal of Cancer Research, Vol.81, No.8, 768-772, 1990.
(DOI: 10.1111/j.1349-7006.1990.tb02643.x,   PubMed: 2168865,   Elsevier: Scopus)
208. Atsushi Saitoh, Hiroshi Iwasaki, Atsuo Nakata, Akio Adachi and Hideo Shinagawa :
Overproduction of human immunodeficiency virus type I reverse transcriptase in Escherichia coli and purification of the enzyme,
Microbiology and Immunology, Vol.34, No.6, 509-521, 1990.
(DOI: 10.1111/j.1348-0421.1990.tb03168.x,   PubMed: 1699113,   Elsevier: Scopus)
209. Hiroyuki Sakai, Riri Shibata, Tomoyuki Miura, Masanori Hayami, Koji Ogawa, Takahiro Kiyomasu, Akinori Ishimoto and Akio Adachi :
Complementation of the rev gene mutation among human and simian lentivuruses,
Journal of Virology, Vol.64, No.5, 2202-2207, 1990.
(PubMed: 2182909)
210. M. Nishimura, Akio Adachi, M. Maeda, A. Ishimoto and J. Kimura :
Human T lymphotropic virus type I may not be associated with multiple sclerosis in Japan,
The Journal of Immunology, Vol.144, No.5, 1684-1688, 1990.
211. M. Nishimura, Akio Adachi, I. Akiguchi, N. Shirahata, M. Maeda, A. Ishimoto, T. Mezaki and J. Kimura :
High ratio of HTLV-1-infected cells in patients with HTLV-1 associated myelopathy(HAM),
Acta Neurologica Scandinavica, Vol.81, No.3, 209-214, 1990.
(DOI: 10.1111/j.1600-0404.1990.tb00968.x,   PubMed: 2353570,   Elsevier: Scopus)
212. Riri Shibata, Tomoyuki Miura, Masanori Hayami, Koji Ogawa, Hiroyuki Sakai, Takahiro Kiyomasu, Ashimoto Ishimoto and Akio Adachi :
Mutational analysis of the human immunodeficiency virus type 2 (HIV-2) genome in relation to HIV-1 and simian immunodeficiency virus SIVagm,
Journal of Virology, Vol.64, No.2, 742-747, 1990.
(PubMed: 2296082)
213. Riri Shibata, Tomoyuki Miura, Masanori Hayami, Hiroyuki Sakai, Koji Ogawa, Takahiro Kiyomasu, Akinori Ishimoto and Akio Adachi :
Construction and characterization of an infectious DNA clone and of mutants of simian immunodeficiency virus isolated from the African green monkey,
Journal of Virology, Vol.64, No.1, 307-312, 1990.
(PubMed: 2293665)
214. R. Shibata, H. Sakai, K. Ogawa, A. Ishimoto and Akio Adachi :
Comparative studies on tat mutants of three primate lentiviruses,
Archives of Virology, Vol.114, No.3-4, 243-250, 1990.
(PubMed: 1700693)
215. Sei-Ichi Endo, Satoshi Kubota, Haruhiko Siomi, Akio Adachi, Stephen Oroszlan, Masatoshi Maki and Masakazu Hatanaka :
A region of basic-amino-acid-cluster in HIV-1 tat protein is essential for trans-acting activity and nucleolar localization,
Virus Genes, Vol.3, No.2, 99-110, 1989.
(DOI: 10.1007/BF00125123,   PubMed: 2559542,   Elsevier: Scopus)
216. Koji Ogawa, Riri Shibata, Takahiro Kiyomasu, Ikuko Higuchi, Yoshihiro Kishida, Akinori Ishimoto and Akio Adachi :
Mutational analysis of the human immunodeficiency virus vpr open reading framev,
Journal of Virology, Vol.63, No.9, 4110-4114, 1989.
(PubMed: 2474678)
217. John Leonard, Jaspal S. Khillan, Howard E. Gendelman, Akio Adachi, Shaun Lorenzo, Heiner Westphal, Malcom A. Martin and Monte S. Meltzer :
The human immunodeficiency virus long terminal repeat is preferentially expressed in Langerhans cells in transgenic mice,
AIDS Research and Human Retroviruses, Vol.5, No.4, 421-430, 1989.
(DOI: 10.1089/aid.1989.5.421,   PubMed: 2548545,   Elsevier: Scopus)
218. Masataka Nishimura, Akio Adachi, Michiyuki Maeda, Ichiro Akiguchi, Masashi Fujita, Masakuni Kameyama and Akinori Ishimoto :
Analysis of the provirus genome integrated in T cell lines establishied from the cerebrospinal fluid of patients with human T lymphotropic virus type 1-associated myelopathy,
Journal of Neuroimmunology, Vol.20, No.1, 33-37, 1988.
(PubMed: 3263389)
219. Gendelman E. Howard, Theodore S. Theodore, Willey Ronald, McCoy John, Akio Adachi, Mervis J. Robert, Venkatesan Sundrarajan and Martin A. Malcolm :
Molecular characterization of a polymerase mutant human immunodeficiency virus,
Virology, Vol.160, No.2, 323-329, 1987.
(DOI: 10.1016/0042-6822(87)90002-X,   PubMed: 2444031,   Elsevier: Scopus)
220. Akinori Ishimoto, Masato Takimoto, Akio Adachi, Masahiro Kakuyama, Shigehisa Kato, Kazuhiro Kakimi, Katsuko Fukuoka, Toshiaki Ogiu and Mutsushi Matsuyama :
Sequences responsible for erythroid and lymphoid leukemia in the long terminal repeats of Friend-MCF and Moloney murine leukemia viruses,
Journal of Virology, Vol.61, No.6, 1861-1866, 1987.
(PubMed: 3033317)
221. Akio Adachi, Scott Koenig, Howard E. Gendelman, Daryl Daugherty, Sebastiano Gattoni-Celli, Anthony S. Fauci and Malcom A. Martin :
Productive, persistent infection of human colorectal cell lines with human immunodeficiency virus,
Journal of Virology, Vol.61, No.1, 209-213, 1987.
(PubMed: 3640832)
222. Howard E. Gendelman, Willam Phelps, Lionel Feigenbaum, Jeffrey M. Ostrove, Akio Adachi, Peter M. Howley, George Khoury, Harold S. Ginsberg and Malcom A. Martin :
Trans-activation of the human immunodeficiency virus long terminal repeat sequence by DNA viruses,
Proceedings of the National Academy of Sciences of the United States of America, Vol.83, No.24, 9759-9763, 1986.
(PubMed: 2432602)
223. Akio Adachi, Howard E. Gendelman, Scott Koenig, Thomas Folks, Ronald Willey, Arnold Rabson and Malcolm A. Martin :
Production of acquired immunodeficiency syndrome-associated retrovirus in human and nonhuman cells transfected with an infectious molecular clone,
Journal of Virology, Vol.59, No.2, 284-291, 1986.
(PubMed: 3016298)
224. Akinori Ishimoto, Akio Adachi, Koji Sakai and Mutsushi Matsuyama :
Long terminal repeat of Friend-MCF virus contains the sequence responsible for erythroid leukemia.,
Virology, Vol.141, No.1, 30-42, 1985.
(DOI: 10.1016/0042-6822(85)90180-1,   PubMed: 3856371,   Elsevier: Scopus)
225. Akio Adachi, Koji Sakai, Naomi Kitamura, Shigetada Nakanishi, Ohtsura Niwa, Mutsushi Matsuyama and Akinori Ishimoto :
Characterization of the env gene and long terminal repeat of molecularly cloned Friend mink cell focus-inducing virus DNA.,
Journal of Virology, Vol.50, No.3, 813-821, 1984.
(PubMed: 6328011)
226. Akio Adachi, Koji Sakai and Akinori Ishimoto :
Isolation and characterization of mink cell focus-inducing murine leukemia viruses with xenotropic host range from mouse strain SL.,
Journal of Virology, Vol.45, No.1, 447-451, 1983.
227. Koji Sakai, Hiroshi Narita, Akio Adachi, Satoru Tsuruta, TToru Yorifuji and Akinori Ishimoto :
Fv-1 determinants in xenotropic murine leukemia viruses studied with biological assay systems: isolation of xenotropic virus with N-tropic Fv-1 activity in the cryptic form.,
Journal of Virology, Vol.42, No.1, 331-336, 1982.
(PubMed: 6283153)
228. Hiroshi Shibuta, Akio Adachi, Tadahito Kanda and Minoru Matumoto :
Experimental parainfluenzavirus infection in mice: fatal illness with atrophy of thymus and spleen in mice caused by a variant of parainfluenza 3 virus,
Infection and Immunity, Vol.35, No.2, 437-441, 1982.
229. Hiroshi Shibuta, Tadahito Kanda, Atsuko Hazama, Akio Adachi and Minoru Matumoto :
Parainfluenza 3 virus: plaque-type variants lacking neuraminidase activity,
Infection and Immunity, Vol.34, No.1, 262-267, 1981.
(PubMed: 6271683,   Elsevier: Scopus)
230. A. Ishimoto, Akio Adachi, K. Sakai, T. Yorifuji and S. Tsuruta :
Rapid emergence of mink cell focus-forming (MCF) virus in various mice infected with NB-tropic Friend virus,
Journal of Virology, Vol.113, No.24, 644-655, 1981.
231. Akio Adachi, Tadahito Kanda and Hiroshi Shibuta :
Isolation and characterization of temperature-sensitive mutants of Sendai virus,
Microbiology and Immunology, Vol.24, No.11, 1053-1068, 1980.
(DOI: 10.1111/j.1348-0421.1980.tb02911.x,   PubMed: 6261090,   Elsevier: Scopus)
232. Hiroshi Shibuta, Tadahito Kanda, Akio Adachi and Yoshiyuki Yogo :
Characterization of bovine parainfluenza virus type 3,
Microbiology and Immunology, Vol.23, No.7, 617-628, 1979.
(DOI: 10.1111/j.1348-0421.1979.tb00502.x,   PubMed: 228163,   Elsevier: Scopus)
233. Hiroshi Shibuta, Akio Adachi, Tadahito Kanda and Hiroyuki Shimada :
Experimental parainfluenzavirus infection. 1. Hydrocephalus of mice due to infection with parainfluenza virus type 1 and type 3,
Microbiology and Immunology, Vol.22, No.8, 505-508, 1978.
(DOI: 10.1111/j.1348-0421.1978.tb00397.x,   PubMed: 214671)

Academic Paper (Unrefereed Paper):

1. M Kurokawa, Hajime A Koyama, S Yasuoka and Akio Adachi :
Influenza virus overcomes apoptosis by rapid multiplication,
International Journal of Molecular Medicine, Vol.3, No.5, 527-530, 1999.
(DOI: 10.3892/ijmm.3.5.527,   PubMed: 10202186)
2. Hajime A Koyama, H Irie, Tomoharu Fukumori, S Hata, S Iida, H Akari and Akio Adachi :
Role of virus-induced apoptosis in a host defense mechanism against virus infection,
The Journal of Medical Investigation : JMI, Vol.45, No.1-4, 37-45, 1998.
(Tokushima University Institutional Repository: 111615,   PubMed: 9864963)
3. Hirofumi Akari, Akio Adachi, Ki-Hoan Nam, K Mori, Isao Otani, Keiji Terao and Yasuhiro Yoshikawa :
Early depletion of peripheral blood CD4+CD8+ T lymphocytes in cynomolgus macaques by SIVmac infection: implication of Nef,
12th World AIDS Conference, Vol.1, 69-73, 1998.
4. Y Kubo, K Higo, H Kobayashi, T Ono, Y Iwama, S Yanagawa, Akio Adachi and A Ishimoto :
Possible origin of murine AIDS-inducing sequence,
Leukemia, Vol.11, No.Suppl 3, 163-166, 1997.
5. Akio Adachi, Meiko Kawamura, Kenzo Tokunaga and Hiroyuki Sakai :
Methods for HIV/SIV gene analysis,
Viral Genome Methods, 45-53, 1996.
6. R Shibata and Akio Adachi :
SIV/HIV recombinants and their use in studying biological properties,
AIDS Research and Human Retroviruses, Vol.8, No.3, 403-409, 1992.
(DOI: 10.1089/aid.1992.8.403,   PubMed: 1571199,   Elsevier: Scopus)
7. R Shibata, Akio Adachi, H Sakai, A Ishimoto, T Miura and M Hayami :
Mutational analysis of simian immunodeficiency virus from African green monkeys and human immunodeficiency virus type 2,
Journal of Medical Primatology, Vol.19, No.3-4, 217-225, 1990.
(PubMed: 2231682)

Review, Commentary:

1. Takaaki Koma, Shun Adachi, Naoya Doi, Akio Adachi and Masako Nomaguchi :
Toward Understanding Molecular Bases for Biological Diversification of Human Coronaviruses: Present Status and Future Perspectives.,
Frontiers in Microbiology, Vol.11, Aug. 2020.
(Tokushima University Institutional Repository: 115602,   DOI: 10.3389/fmicb.2020.02016,   PubMed: 32983025)
2. Masako Nomaguchi, Naoya Doi, Takaaki Koma and Akio Adachi :
HIV-1 mutates to adapt in fluxing environments.,
Microbes and Infection, Oct. 2018.
(DOI: 10.1016/j.micinf.2017.08.003,   PubMed: 28859896)
3. Masako Nomaguchi and Akio Adachi :
[HIV infection].,
Nihon Rinsho. Japanese Journal of Clinical Medicine, Vol.68 Suppl 8, 518-522, Aug. 2010.
(PubMed: 20976926)

Proceeding of International Conference:

1. T. Sultana, E.E. Nakayama, S. Tobita, M. Yokoyama, Y. Seki, A. Saito, Masako Nomaguchi, Akio Adachi, H. Akari, H. Sato and T. Shioda :
Novel mutant human immunodeficiency virus type 1 strains with high degree of resistance to cynomolgus macaque TRIMCyp generated by random mutagenesis.,
The 23rd Conference on Retroviruses and Opportunistic Infections, Boston, USA, Feb. 2016.
2. A Sato, Masako Nomaguchi, K Kono, E.E. Nakayama, T Shioda, T Yoshida, Y Yasutomi, T Matano, Akio Adachi and H Akari :
Genotypic variation of cynomolgus monkey trim5alpha determines the susceptibility to monkey-tropic HIV-1 infection.,
XV International Congress of Virology, Sep. 2011.
3. N Takahashi, A Saito, Masako Nomaguchi, Akio Adachi, H Akari and T Matano :
Viral recovery from cynomolgus macaques controlling a simian-tropic HIV-1 challenge.,
XV International Congress of Virology, Sep. 2011.
4. Ariko Miyake, Doi Naoya, Fujiwara Sachi, Akio Adachi and Masako Nomaguchi :
Analysis of growth adaptive mutations in HIV-1 genome identifies a pol-intergrase region that enhances virion production in a cell-independent and codon triplet-dependent manner.,
The 10th Awaji International Forum on Infection and Immunity, Awaji, Japan, Sep. 2010.
5. Mikako Fujita, Boonruang Khamsri, Fumiko Murao, Akiko Yoshida, Akiko Sakurai, Tsuneo Uchiyama, K Kamada, H Shirai, Yo Matsuo and Akio Adachi :
Comparative study on the structure and cytopathogenic activity of HIV Vpr/Vpx proteins,
5th Awaji International Forum on Infection and Immunity, Sumoto, Japan, Sep. 2005.

Proceeding of Domestic Conference:

1. Bao Quoc Le, Yokoyama Masaru, Naoya Doi, ICHINOMIYA Takumi, KOMODA Nanako, Tomoyuki Kondo, Akio Adachi, Kotani Osamu, Sato Hironori, Masako Nomaguchi and Takaaki Koma :
The importance of a novel ITI triplet motif within Env V3 domain for R5-tropic HIV-1 replication,
第70回日本ウイルス学会学術集会, Sep. 2023.
2. Takaaki Koma, RE Kuokku Bao, Naoya Doi, KOMODA Nanako, ICHINOMIYA Takumi, Tomoyuki Kondo, Akio Adachi and Masako Nomaguchi :
Implications of Gag-NC and gRNA interactions in HIV-1 assembly,
第70回日本ウイルス学会学術集会, Sep. 2023.
3. Tomoyuki Kondo, Takaaki Koma, Naoya Doi, RE Kuokku Bao, KOMODA Nanako, ICHINOMIYA Takumi, Akio Adachi and Masako Nomaguchi :
Effect of naturally-occurring synonymous single-nucleotide mutations within the vpr-coding sequence on HIV-1 replication,
第70回日本ウイルス学会学術集会, Sep. 2023.
4. Naoya Doi, Takaaki Koma, LE Quoc Bao, KOMODA Nanako, ICHINOMIYA Takumi, Tomoyuki Kondo, Akio Adachi and Masako Nomaguchi :
PIM kinases suppress HIV virion production by inhibiting viral protein expression,
第70回日本ウイルス学会学術集会, Sep. 2023.
5. Takaaki Koma, 小谷 治, Naoya Doi, Tomoyuki Kondo, 横山 勝, Akio Adachi, 佐藤 裕徳 and Masako Nomaguchi :
HIV-1 Gag MAのGag二量体化における役割の解明,
第36回日本エイズ学会, Nov. 2022.
6. Tomoyuki Kondo, Takaaki Koma, Akio Adachi, Masako Nomaguchi and Naoya Doi :
PIMキナーゼによるHIV型特異的な遺伝子発現調節の解析,
第36回日本エイズ学会学術集会・総会, Nov. 2022.
7. Naoya Doi, Takaaki Koma, Chisato Gotohda, NAGASAKA Mari, Tomoyuki Kondo, Akio Adachi and Masako Nomaguchi :
Importance of vpr-coding sequence in HIV-1 gene expression,
第69回日本ウイルス学会学術集会, Nov. 2022.
8. Tomoyuki Kondo, Takaaki Koma, UDAGAWA Mei, OKUMURA Nozomi, Akio Adachi, Masako Nomaguchi and Naoya Doi :
Analysis of HIV type-specific regulation of viral gene expression by PIM,
第69回日本ウイルス学会学術集会, Nov. 2022.
9. Takaaki Koma, 小谷 治, Naoya Doi, Tomoyuki Kondo, 横山 勝, Akio Adachi, 佐藤 裕徳 and Masako Nomaguchi :
HIV-1 Gag-MAにおけるGag前駆体二量体化部位のウイルス学的解析,
第69回日本ウイルス学会, Nov. 2022.
10. Tomoyuki Kondo, Takaaki Koma, Akio Adachi, Masako Nomaguchi and Naoya Doi :
PIMキナーゼ及びPIM阻害剤によるHIV種特異的な遺伝子発現と複製への影響,
第265回徳島医学会学術集会, Jul. 2022.
11. Takaaki Koma, Mitsuki Ishizue, Chizuko Tsukada, Chiaki Tokaji, Akio Adachi, Masako Nomaguchi and Naoya Doi :
PIMキナーゼ阻害剤がHIV種特異的に複製に及ぼす影響の解析(若手優秀演題),
第35回日本エイズ学会学術集会・総会, Nov. 2021.
12. Takaaki Koma, Naoya Doi, Chizuko Tsukada, Chiaki Tokaji, Mitsuki Ishizue, Akio Adachi and Masako Nomaguchi :
HIV-1 vpr塩基配列の同義一塩基置換がウイルス複製に与える影響,
第68回日本ウイルス学会, Nov. 2021.
13. 小谷 治, Takaaki Koma, 宮川 敬, 梁 明秀, 横山 勝, Naoya Doi, Akio Adachi, Masako Nomaguchi and 佐藤 裕徳 :
HIV-1カプシド ''disorder'' 領域の構造機能解析,
第33回日本エイズ学会学術集会, Nov. 2019.
14. Takaaki Koma, Naoya Doi, Akio Adachi and Masako Nomaguchi :
HIV-1 Gag集合初期に関わる内在性集合促進因子の探索,
第33回日本エイズ学会学術集会, Nov. 2019.
15. Takaaki Koma, Naoya Doi, Satoshi Nakashima, Akio Adachi and Masako Nomaguchi :
Exploration for assembly-promoting factors involved in the early stage of HIV-1 Gag assembly,
第67回日本ウイルス学会学術集会, Oct. 2019.
16. Masako Nomaguchi, Takaaki Koma, Naoya Doi, Hideki Yamamoto, Kyosuke Watanabe, Mai Takemoto and Akio Adachi :
Molecular bases for determination of the Vif expression level by single-nucleotide mutations within SA1D2prox and by adaptive mutations in the HIV-1 genome,
第67回日本ウイルス学会学術集会, Oct. 2019.
17. Naoya Doi, Takaaki Koma, Akio Adachi and Masako Nomaguchi :
Analysis of molecular mechanism on species-specific growth enhancement by a single-amino acid mutation in V3 tip of CCR5-tropic HIV-1 Env,
第67回日本ウイルス学会学術集会, Oct. 2019.
18. Takaaki Koma, 小谷 治, Naoya Doi, 宮川 敬, 梁 明秀, 横山 勝, 佐藤 裕徳, Akio Adachi and Masako Nomaguchi :
リンカードメインによるGag集合・ウイルス産生・感染性に関わるHIV-1カプシド構造のアロステリック制御,
第34回中国四国ウイルス研究会, Jun. 2019.
19. Masako Nomaguchi, Naoya Doi, Takaaki Koma, 吉田 和子 and Akio Adachi :
SA1D2proxに関するHIV-1 Vif低発現変異体NL-gatは,Vif発現量適応変異あるいはenv変異の獲得により増殖能を向上させる,
第66回日本ウイルス学会学術集会, Oct. 2018.
20. Akio Adachi, Naoya Doi, Takaaki Koma, Hayato Ohkubo, 吉田 和子 and Masako Nomaguchi :
SA1D2prox領域に関するHIV-1 Vif超低発現変異体 NL-tacのAPOBEC3G高発現下における適応過程の解析,
第66回日本ウイルス学会学術集会, Oct. 2018.
21. Takaaki Koma, 小谷 治, Naoya Doi, 宮川 敬, 梁 明秀, 横山 勝, 佐藤 裕徳, Akio Adachi and Masako Nomaguchi :
HIV-1複製後期過程におけるGag-CAリンカードメインの役割,
第66回日本ウイルス学会学術集会, Oct. 2018.
22. Naoya Doi, Takaaki Koma, Nina Nakanishi, Akio Adachi and Masako Nomaguchi :
馴化型R5-tropic HIV-1rmtで同定されたEnvによる増殖促進の解析,
第66回日本ウイルス学会学術集会, Oct. 2018.
23. Shoko Nakanishi, Sakimi Watanabe, Naoya Doi, Takaaki Koma, Akio Adachi and Masako Nomaguchi :
Single-amino acid mutations in V1 and C4 domains of HIV-1 Env cooperatively enhance viral replication ability by increasing CD4 affinity,
第65回日本ウイルス学会学術集会, Oct. 2017.
24. Sakimi Watanabe, Shoko Nakanishi, Takaaki Koma, Naoya Doi, Akio Adachi and Masako Nomaguchi :
Low vif type of HIV-1 SA1D2prox variants can adaptively mutate to enhance the Vif expression under the strong restrictive condition,
第65回日本ウイルス学会学術集会, Oct. 2017.
25. Naoya Doi, Takaaki Koma, Shoko Nakanishi, Sakimi Watanabe, Masako Nomaguchi and Akio Adachi :
Generation of R5-tropic HIV-1rmt clones with an enhanced replication ability by adaptive Env domain swapping,
第65回日本ウイルス学会学術集会, Oct. 2017.
26. Akio Adachi, Naoya Doi, Takaaki Koma, Shoko Nakanishi, Sakimi Watanabe and Masako Nomaguchi :
Linkage analysis of HIV-1 vif production level and SLSA1 structure/energy stability,
第65回日本ウイルス学会学術集会, Oct. 2017.
27. Takaaki Koma, Naoya Doi, 宮川 敬, 梁 明秀, Akio Adachi and Masako Nomaguchi :
Role for amino acid residues S149 and I150 of the Gag-CA linker domain in the late HIV-1 replication phase,
第65回日本ウイルス学会学術集会, Oct. 2017.
28. 酒井 遥介, 藤本 薫平, 土肥 直哉, Masako Nomaguchi and Akio Adachi :
Studies on the adaptation process of HIV-1 Env in macaque cells,
第64回日本ウイルス学会学術集会, Oct. 2016.
29. A Kawakami, A Himeno, M Kikukawa, Y Ishida, Masako Nomaguchi, Akio Adachi and T Miura :
Generation of neutralization-resistant and CCR5 tropic HIV-1rmt,
第64回日本ウイルス学会学術集会, Oct. 2016.
30. N Doi, Chieko Ishifune, Koji Yasutomo, T Miura, Y Sakai, K Fujimoto, S Harada, K Yoshimura, Masako Nomaguchi and Akio Adachi :
Replication and pathogenicity of HIV-1rmt: towards evaluation of viral growth ability in gut-derived cells,
第64回日本ウイルス学会学術集会, Oct. 2016.
31. Masako Nomaguchi, 土肥 直哉, 藤本 薫平, 酒井 遥介, 中西 祥子 and Akio Adachi :
Identification of cis-elements involved in the HIV-1 vif mRNA production,
第64回日本ウイルス学会学術集会, Oct. 2016.
32. Akio Adachi, 土肥 直哉, 酒井 遥介, 藤本 薫平 and Masako Nomaguchi :
An ultra-low vif type of HIV-1 SA1D2prox variant can adapt and evolve under the high level of APOBEC3G,
第64回日本ウイルス学会学術集会, Oct. 2016.
33. 藤本 薫平, 土肥 直哉, 酒井 遥介, Akio Adachi and Masako Nomaguchi :
Effects of mutations in HIV-1 Gag-CA helix 7 and linker domain on the virion production,
第64回日本ウイルス学会学術集会, Oct. 2016.
34. S. Tahmina, E.E. Nakayama, S. Tobita, A. Saito, Masako Nomaguchi, Akio Adachi, H. Akari and T. Shioda :
Novel mutant HIV-1 strains with high degree of resistance to cynomolgus macaque TRIMCyp generated by random mutagenesis.,
The 63rd Annual Meeting of the Japanese Society for Virology, Nov. 2015.
35. 酒井 遥介, 土肥 直哉, 宮崎 恭行, Akio Adachi and Masako Nomaguchi :
HIV-1 Gag-CA I134/I135/S149の1アミノ酸変異はウイルス複製後期過程に影響する.,
第63回日本ウイルス学会学術集会, Nov. 2015.
36. 土肥 直哉, Masako Nomaguchi, 酒井 遥介 and Akio Adachi :
CCR-5tropicアカゲザル指向性HIV-1の構築とウイルス学的性状解析.,
第63回日本ウイルス学会学術集会, Nov. 2015.
37. Akio Adachi, 土肥 直哉, 酒井 遥介, 吉田 知哉, 宮崎 恭行 and Masako Nomaguchi :
HIV-1 Vif発現量を増減させるSA1D2prox塩基配列の同定.,
第63回日本ウイルス学会学術集会, Nov. 2015.
38. Masako Nomaguchi, 土肥 直哉, 吉田 知哉, 酒井 遥介, 宮崎 恭行 and Akio Adachi :
SA1proxの1塩基置換によるHIV-1 Vif発現量変動機構.,
第63回日本ウイルス学会学術集会, Nov. 2015.
39. Akio Adachi :
抗HIV細胞因子と抗HIV戦略.,
第28回日本エイズ学会学術集会, Dec. 2014.
40. 土肥 直哉, Yasuyuki Miyazaki, 酒井 遥介, Taisuke Izumi, Tsuneo Uchiyama, Akio Adachi and Masako Nomaguchi :
HIV-1 Gag-CAへリックス7の変異がウイルス複製後期過程に及ぼす影響の解析.,
第62回日本ウイルス学会学術集会, Nov. 2014.
41. Yasuyuki Miyazaki, Taisuke Izumi, Masako Nomaguchi, Tsuneo Uchiyama and Akio Adachi :
In vitro構築系を用いたHIV-1/HIV-2 CA重合能の関する解析.,
第62回日本ウイルス学会学術集会, Nov. 2014.
42. 酒井 遥介, 笹田 ひかり, 土肥 直哉, Taisuke Izumi, Yasuyuki Miyazaki, Akio Adachi and Masako Nomaguchi :
HIV/SIV Vpx蛋白質の発現調節に寄与する領域の解析.,
第62回日本ウイルス学会学術集会, Nov. 2014.
43. Masako Nomaguchi, 土肥 直哉, 酒井 遥介, Taisuke Izumi, Yasuyuki Miyazaki and Akio Adachi :
SA1prox1の遺伝子配列はVif/APOBEC3G依存的にウイルス複製能を変動させる.,
第62回日本ウイルス学会学術集会, Nov. 2014.
44. チッフチ ハリル イブラヒム, 古賀 涼子, 岩谷 靖雅, Masako Nomaguchi, Akio Adachi, 大塚 雅巳 and 藤田 美歌子 :
SAMHD1-independent function of HIV-2 Vpx protein.,
第27回日本エイズ学会学術集会, Nov. 2013.
45. 齊藤 暁, 大附 寛幸, 東濃 篤徳, 鈴木 紗織, 松田 健太, 高橋 尚史, 松岡 佐織, 岩谷 靖雅, 杉浦 亙, Masako Nomaguchi, Akio Adachi, 保富 康宏, 俣野 哲朗, 三浦 智行 and 明里 宏文 :
CCR5指向性を示す新規サル指向性HIV-1はサル個体に持続感染する.,
第27回日本エイズ学会学術集会, Nov. 2013.
46. 山本 充奈美, Masako Nomaguchi, 古賀 涼子, 岩谷 靖雅, 高宗 暢暁, 三隅 将吾, 大塚 雅巳, Akio Adachi and 藤田 美歌子 :
マクロファージにおけるSAMHD1非依存的なHIV-2 Vpxの機能.,
第61回日本ウイルス学会学術集会, Nov. 2013.
47. Ariko Miyake, Yasuyuki Miyazaki, Masako Nomaguchi and Akio Adachi :
Vpx発現におけるC末端ポリプロリンモチーフの機能の解析.,
第61回日本ウイルス学会学術集会, Nov. 2013.
48. 齊藤 暁, 大附 寛幸, 東濃 篤徳, 鈴木 紗織, 松田 健太, 高橋 尚史, 松岡 佐織, 岩谷 靖雅, 杉浦 亙, Masako Nomaguchi, Akio Adachi, 保富 康宏, 俣野 哲朗, 三浦 智行 and 明里 宏文 :
CCR5指向性を示す新規サル指向性HIV-1はサル個体に持続感染する.,
第61回日本ウイルス学会学術集会, Nov. 2013.
49. Akio Adachi, 土肥 直哉, 藤原 佐知 and Masako Nomaguchi :
アカゲザルPBMCで効率よく増殖するHIV-1mtの構築.,
第61回日本ウイルス学会学術集会, Nov. 2013.
50. 土肥 直哉, 藤原 佐知, 酒井 遥介, 大久保 綾香, 山根 瑞萌, Akio Adachi and Masako Nomaguchi :
R5-tropic HIV-1mt Env適応変異の宿主細胞依存性増殖促進機構の解析.,
第61回日本ウイルス学会学術集会, Nov. 2013.
51. Yasuyuki Miyazaki, Ariko Miyake, Masako Nomaguchi, Tsuneo Uchiyama and Akio Adachi :
In vitro再構築系を用いたHIV-1/HIV-2 CAアセンブリーの安定性に関する解析.,
第61回日本ウイルス学会学術集会, Nov. 2013.
52. Masako Nomaguchi, Ariko Miyake, 土肥 直哉, 藤原 佐知, Yasuyuki Miyazaki, 横田 恭子, 横山 勝, 佐藤 裕徳, 増田 貴夫 and Akio Adachi :
HIV-1 pol(4895-4933)の1塩基置換によるウイルス複製制御機構の解析.,
第61回日本ウイルス学会学術集会, Nov. 2013.
53. 藤野 悠那, Ariko Miyake, 古賀 涼子, 川村 宗吾, 大出 裕高, 岩谷 靖雅, Masako Nomaguchi, Akio Adachi, 大塚 雅巳, Yasuyuki Miyazaki and 藤田 美歌子 :
HIV-2 Vpx 富プロリン領域の機能.,
第26回日本エイズ学会学術集会, Nov. 2012.
54. Masako Nomaguchi, Ariko Miyake, 土肥 直哉, 藤原 佐知, Yasuyuki Miyazaki and Akio Adachi :
HIV-1 インテグラーゼ C末端領域の1塩基置換によるウイルス複製制御機構の解析.,
第60回日本ウイルス学会学術集会, Nov. 2012.
55. 藤田 美歌子, Masako Nomaguchi, 古賀 涼子, 藤野 悠那, 大塚 雅巳 and Akio Adachi :
SAMHD1 非依存的な HIV-2 Vpx の機能.,
第60回日本ウイルス学会学術集会, Nov. 2012.
56. Ariko Miyake, 藤野 悠那, 古賀 涼子, 川村 宗吾, 大出 裕高, 岩谷 靖雅, Masako Nomaguchi, Akio Adachi, 大塚 雅巳, 藤田 美歌子 and Yasuyuki Miyazaki :
Vpx 発現における C末端ポリプロリンモチーフの機能の解析.,
第60回日本ウイルス学会学術集会, Nov. 2012.
57. Yasuyuki Miyazaki, Ariko Miyake, Masako Nomaguchi, Tsuneo Uchiyama and Akio Adachi :
in vitro 再構築系を用いた HIV-2 CA アセンブリーの安定性に関する解析.,
第60回日本ウイルス学会学術集会, Nov. 2012.
58. 土肥 直哉, 藤原 佐知, 酒井 遥介, 松本 唯, Akio Adachi and Masako Nomaguchi :
R5-tropic HIV-1mt NL-DT562 の Env 適応変異による増殖促進機構の解析.,
第60回日本ウイルス学会学術集会, Nov. 2012.
59. 齊藤 暁, 河野 健, 中山 英美, Akio Adachi, Masako Nomaguchi, 保富 康宏, 俣野 哲朗, 塩田 達雄 and 明里 宏文 :
サル指向性HIV-1への感受性に影響を与えるマカクサルTRIM5遺伝子の多様性.,
第25回日本エイズ学会学術集会, Dec. 2011.
60. Masako Nomaguchi, 土肥 直哉, 藤原 佐知 and Akio Adachi :
Gag-CAおよびVpuの改変によるサル細胞でのHIV複製の増強.,
第25回日本エイズ学会学術集会, Dec. 2011.
61. 高橋 尚史, 齊藤 暁, Masako Nomaguchi, 松岡 佐織, Akio Adachi, 明里 宏文 and 俣野 哲朗 :
サル指向性HIV-1感染慢性潜伏期のカニクイサルからの感染性ウイルスの回収.,
第25回日本エイズ学会学術集会, Nov. 2011.
62. Akio Adachi and Masako Nomaguchi :
HIV-1宿主域を規定する細胞因子とウイルス蛋白質.(シンポジウム4),
第24回日本エイズ学会学術集会, Nov. 2010.
63. Masako Nomaguchi, 齊藤 暁, 明里 宏文, 土肥 直哉, 藤原 佐知, Ariko Miyake, 横山 勝, 大出 裕高, 佐藤 裕徳 and Akio Adachi :
サル細胞で効率よく増殖するHIV-1の構築ーアカゲザルTRIM5αとtetherinによる抑制の回避ー.,
第24回日本エイズ学会学術集会, Nov. 2010.
64. 齊藤 暁, 河野 健, 黒石 歩, 中山 英美, 塩田 達雄, Akio Adachi, Masako Nomaguchi, 安富 康宏, 俣野 哲朗 and 明里 宏文 :
カニクイザルTRIM5α alleleがサル指向性HIV-1の増殖に与えるインパクト.,
第24回日本エイズ学会学術集会, Nov. 2010.
65. Ariko Miyake, 土肥 直哉, 藤原 佐知, Akio Adachi and Masako Nomaguchi :
HIV-1増殖過程におけるインテグラーゼ(IN)C末端領域(CTD)の影響.(ワークショップ),
第24回日本エイズ学会学術集会, Nov. 2010.
66. Masako Nomaguchi, 土肥 直哉, 藤原 佐知, Ariko Miyake, 横山 勝, 大出 裕高, 佐藤 裕徳 and Akio Adachi :
アカゲザルに存在する抗HIV-1因子TRIM5αとtetherinを回避するサル細胞指向性HIV-1の構築.,
第58回日本ウイルス学会学術集会, Nov. 2010.
67. 土肥 直哉, 齊藤 暁, 明里 宏文, 藤原 佐知, Ariko Miyake, 横山 勝, 大出 裕高, 佐藤 裕徳, Akio Adachi and Masako Nomaguchi :
サル指向性HIV-1 CAの1アミノ酸変異はサル細胞での増殖を促進する.,
第58回日本ウイルス学会学術集会, Nov. 2010.
68. Ariko Miyake, 土肥 直哉, 藤原 佐知, Akio Adachi and Masako Nomaguchi :
HIV-1インテグラーゼ(IN)C末端領域(CTD)における1塩基置換によるウイルス増殖促進機構の解析.,
第58回日本ウイルス学会学術集会, Nov. 2010.
69. Hirokazu Miyoshi, 立花 さやか, Takuya Saze, Namiko Irikura, Yoshinori Kuwahara, Akio Adachi and Hiroshi Maezawa :
コース別再教育訓練の計画と実施及びその分析続報,
日本放射線安全管理学会 第6回学術大会, Dec. 2007.
70. Yoshinori Kuwahara, 立花 さやか, Namiko Irikura, Hirokazu Miyoshi, Takuya Saze, Hiroshi Maezawa and Akio Adachi :
払い出しから引き渡しまでの管理ソフトウエアの開発,
日本放射線安全管理学会 第5回学術大会, Dec. 2006.
71. Namiko Irikura, Hirokazu Miyoshi, Takuya Saze, Yoshinori Kuwahara, 立花 さやか, 合田 康代, Akio Adachi and Hiroshi Maezawa :
管理区域における労働安全衛生法への対応,
日本放射線安全管理学会 第5回学術大会, Dec. 2006.
72. Hirokazu Miyoshi, Namiko Irikura, Takuya Saze, Yoshinori Kuwahara, 合田 康代, 立花 さやか, Akio Adachi and Hiroshi Maezawa :
定期検査・定期確認の事例-徳島大学アイソトープ総合センター-,
日本アイソトープ協会, Nov. 2006.
73. Yoshinori Kuwahara, 圓藤 紀子, Namiko Irikura, Hirokazu Miyoshi, Takuya Saze and Akio Adachi :
RIの入庫から廃棄までの管理ソフトの開発,
日本放射線安全管理学会, Nov. 2005.
74. Namiko Irikura, 菱本 純次, 花見 孝行, Yoshinori Kuwahara, Hirokazu Miyoshi, Takuya Saze and Akio Adachi :
放射性有機廃液焼却装置運転のコストについて,
Nov. 2005.
75. Namiko Irikura, 圓藤 紀子, Yoshinori Kuwahara, Akio Adachi, Hirokazu Miyoshi and Takuya Saze :
RI施設のオリエンテーションについて,
Nov. 2005.
76. Hirokazu Miyoshi, 圓藤 紀子, Namiko Irikura, Yoshinori Kuwahara, Takuya Saze, 山本 康代 and Akio Adachi :
RI施設の運営状況-徳島大学アイソトープ総合センター-,
日本放射線安全管理学会, Nov. 2005.
77. Mikako Fujita, カムセー ブンルアン, 櫻井 明子, アブハイ ジェレ, Tsuneo Uchiyama and Akio Adachi :
HIV-2 VpxおよびVprの発現量の解析,
第52回日本ウイルス学会学術集会, Nov. 2004.
78. Namiko Irikura, Yoshinori Kuwahara, 山本 康代, 圓藤 紀子, Takuya Saze, Hirokazu Miyoshi and Akio Adachi :
徳島大学における作業環境測定,
Jan. 2004.
79. 菅原 文博, 坂口 剛正, Tsuneo Uchiyama, Akio Adachi and 吉田 哲也 :
ウイルス様粒子を用いたセンダイウイルス出芽の解析,
第51回日本ウイルス学会学術集会, Oct. 2003.
80. Hirokazu Miyoshi, Hiromu Nishitani, Akio Adachi, 佐藤 晃一, Tokue Kuroda, 長谷川 豊司, Akemi Matsushima and Yousuke Takahama :
放射能デモンストレーションキットを用いた教育訓練の実施,
日本放射線安全管理学会 第1回学術大会, Dec. 2002.
81. Tomoharu Fukumori, 明里 宏文, 飯田 慎也, Tsuneo Uchiyama and Akio Adachi :
HIV-1 vif 遺伝子変異体のウイルス粒子構造の解析,
第46回日本ウイルス学会学術集会, Oct. 1998.

Et cetera, Workshop:

1. Hirokazu Miyoshi, Hiroshi Maezawa, Takuya Saze, Yoshinori Kuwahara, Namiko Irikura, 立花 さやか and Akio Adachi :
徳島大学アイソトープ総合センター概要2007年度版,
Apr. 2007.
2. Hirokazu Miyoshi, Hiroshi Maezawa, Akio Adachi, Takuya Saze, Namiko Irikura, Yoshinori Kuwahara, 立花 さやか, Tatsuhiro Ishida, Akihiko Tsuji, Takao Hanabusa, Toshihiro Moriga, 鬼島 明洋, Eiichi Honda, Seiji Iwamoto, 佐藤 一雄, Shunsuke Furutani and Yasuhiko Morita :
徳島大学アイソトープ総合センターニュース,
徳島大学アイソトープ総合センターニュース, Vol.6, 1-42, Mar. 2007.
3. 佐藤 一樹, 坂口 暁, Hiroaki Muguruma, Seiji Yano, Saburo Sone, Tsuneo Uchiyama and Akio Adachi :
発疹熱の一症例,
第227回徳島医学会, Jul. 2003.

Grants-in-Aid for Scientific Research (KAKEN Grants Database @ NII.ac.jp)

  • Analysis of molecular basis for modulation of HIV-1 replication by naturally-occurring single nucleotide polymorphisms within the SLSA1 structure of the pol gene (Project/Area Number: 26460556 )
  • Basic study on HIV-1 replication and pathogenicity in host individuals: functional analysis of accessory proteins (Project/Area Number: 26293104 )
  • New anti-HIV/SIV cellular-factors counteracted by Vpx: their search and identification (Project/Area Number: 24659208 )
  • HIV-1宿主域の分子基盤に関する基礎研究 (Project/Area Number: 21022033 )
  • Structural and functional analysis of the mechanism for HIV-1 evolution/ adaptation (Project/Area Number: 21390141 )
  • HIV-1宿主域の分子基盤に関するウイルス学的研究 (Project/Area Number: 19041051 )
  • Molecular and virological analysis of simian and human cell-tropic HIV-1 (Project/Area Number: 18390140 )
  • HIVの複製・病原性発現に必須なアクセサリー蛋白質の系統的構造・機能相関解析 (Project/Area Number: 16017270 )
  • Regulation of HIV replication by proteasome degradation of Vif (Project/Area Number: 15590420 )
  • HIV/SIV Gagハイブリッドウイルスの作製とその解析 (Project/Area Number: 14657076 )
  • Functional domain analysis of HIV accessory proteins (Project/Area Number: 14370103 )
  • HIV病原性解析のための新規感染実験システムの確立 (Project/Area Number: 14021078 )
  • HIVアクセサリー蛋白質Vpx/Vprの機能解析 (Project/Area Number: 13015213 )
  • Studies on apoptosis induced in the virus-infected cells (Project/Area Number: 11670298 )
  • Basic studies on strategy against HIV (Project/Area Number: 11557024 )
  • Cell biology of HIV-1 Nef and Vpr (Project/Area Number: 10470078 )
  • Basic Research for AIDS control A01 ; Host factors necessary for HIV-1 replication (Project/Area Number: 10180101 )
  • 遺伝子鏡を用いたマラリア感染に対するDNAワクチネーションの基礎的研究 (Project/Area Number: 09877055 )
  • エイズの病態と制御に関する基礎研究 柱1.HIVの複製機構 (Project/Area Number: 07277104 )
  • Pathogenesis and Control of AIDS (Project/Area Number: 07277101 )
  • Identification of pathogenic sequence of MAIDS virus (Project/Area Number: 06670326 )
  • エイズ研究の現状と展望 (Project/Area Number: 06354031 )
  • レトロウイルス発癌に向けた遺伝子治療法開発の基礎的研究 (Project/Area Number: 06282227 )
  • ヒトレトロウイルス調節遺伝子の互換性の機構 (Project/Area Number: 05670279 )
  • エイズ制圧に向けての基礎研究 柱1 HIVの分子遺伝学 (Project/Area Number: 04269104 )
  • マウス乳がんウイルスによる白血病発生機構の解析 (Project/Area Number: 04152060 )
  • エイズの総合的基礎研究 柱1.HIVの構造と機能に関する研究 (Project/Area Number: 03219103 )
  • 感染症DNAク-ロンを用いたHIU/SIUの病原性と変異の解析 (Project/Area Number: 03152062 )
  • エイズの総合的基礎研究 柱1.HIVの構造と機能に関する研究 (Project/Area Number: 02235103 )
  • マウス乳癌ウイルス変異株の白血病誘導能獲得の分子機構の解析 (Project/Area Number: 02152051 )
  • エイズの総合的基礎研究 柱1、HIVの構造と機能に関する研究 (Project/Area Number: 01653001 )
  • ヒト免疫不全症候群ウイルス(HIV)の潜伏持続感染・再活性化機構の研究 (Project/Area Number: 63015037 )
  • 白血病ウイルスの増殖・内在化・遺伝子発現 (Project/Area Number: 63010013 )
  • 発癌性レトロウイルスとヒト後天性免疫不全症候群ウイルスの増殖機構の比較検討 (Project/Area Number: 62015041 )
  • 都市型のがんの特性と要因に関する病理疫学的研究 (Project/Area Number: 62010018 )
  • 白血病ウイルスの増殖・内在化・遺伝子発現 (Project/Area Number: 62010017 )
  • Search by Researcher Number (90127043)