徳島大学 / 教育研究者総覧 --- 渡邉佳一郎

専門分野

研究テーマ

著書・論文

著書:

1.	Deguchi Toru and Keiichiro Watanabe : Clinical Outcomes with TADs and Conventional Mechanics in Adult Skeletal Open Bite and Class II Patients., Apr. 2020.
2.	Deguchi Toru and Keiichiro Watanabe : Chapter 13 Application of Buccal TADs for Distalization of Teeth, Elsevier, Jan. 2020.
3.	市原亜起, 渡邉佳一郎, 堀内信也, 田中栄二 : アンカースクリューによって\|3埋伏歯の開窓牽引を行った症例, 医歯薬出版株式会社, 東京, 2019年.
4.	田中栄二, 天眞寛文, 森浩喜, 渡邉佳一郎 : B-maxスクリュー Type-TKを用いた成人開咬の治療戦略, クインテッセンス出版株式会社, 東京, 2018年.

学術論文(審査論文):

1.	Keiichiro Watanabe, Eiji Tanaka, Kohei Kamoi, Antonin Tichy, Takahiko Shiba, Kazuhide Yonerakura, Masatoshi Nakajima, Ruonan Han and Keiichi Hosaka : A dual composite resin injection molding technique with 3D-printed flexible indices for biomimetic replacement of a missing mandibular lateral incisor., Journal of Prosthodontic Research, 2024. (要約) The bilayered direct composite RBFPD using 3D printed flexible indices prepared with a full digital workflow has several advantages over other dental prosthetic solutions, including noninvasiveness, cost-effectiveness, biomimetic esthetics, repairability, and shortened treatment times. Although the initial results are promising, further longitudinal studies with larger patient cohorts are required to confirm the long-term efficacy of this approach. (出版サイトへのリンク) ● Publication site (DOI): 10.2186/jpr.JPR_D_23_00239 (文献検索サイトへのリンク) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 38479888 ● Search Scopus @ Elsevier (PMID): 38479888 ● Search Scopus @ Elsevier (DOI): 10.2186/jpr.JPR_D_23_00239 (DOI: 10.2186/jpr.JPR_D_23_00239, PubMed: 38479888)
2.	Keiichi Hosaka, Antonin Tichy, Monica Yamauti, Keiichiro Watanabe, Kohei Kamoi, Kazuhide Yonekura, Richard Foxton and Masatoshi Nakajima : Digitally Guided Direct Composite Injection Technique with a Bi-layer Clear Mini-Index for the Management of Extensive Occlusal Caries in a Pediatric Patient: A Case Report., The Journal of Adhesive Dentistry, Vol.25, No.1, 211-218, 2023. (要約) The injection technique with a bi-layer clear mini-index accurately translated the digital wax-ups into large, final restorations. Precise morphology and shortened chair time enhanced patient satisfaction, but at the expense of multiple visits. (徳島大学機関リポジトリ) ● Metadata: 118656 (出版サイトへのリンク) ● Publication site (DOI): 10.3290/j.jad.b4515527 (文献検索サイトへのリンク) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 37843503 ● Search Scopus @ Elsevier (PMID): 37843503 ● Search Scopus @ Elsevier (DOI): 10.3290/j.jad.b4515527 (徳島大学機関リポジトリ: 118656, DOI: 10.3290/j.jad.b4515527, PubMed: 37843503)
3.	田中茉里子, 堀内信也, 日浅雅博, 渡邉佳一郎, 岩浅亮彦, 髙丸菜都美, 永井宏和, 宮本洋二, 田中栄二 : 術後に顎関節に疼痛を訴えた顎偏位を伴う骨格性上顎前突症例, 中·四国矯正歯科学会雑誌, Vol.35, No.1, 77-86, 2023年.
4.	花輪茂己, 日浅雅博, 岩浅亮彦, 渡邉佳一郎, 天眞寛文, 木内奈央, 堀内信也, 田中栄二 : 上顎左側第二小臼歯先天欠如を伴う片側性唇顎口蓋裂患者に対して下顎左側第二小臼歯を移植した一症例．, 中·四国矯正歯科学会雑誌, Vol.35, No.1, 67-76, 2023年. (キーワード) 中・四国矯正歯科学会雑誌 35(1):67-76.
5.	Keiichiro Watanabe, A Tichy, Kouhei Kamoi, Masahiro Hiasa, Kazuhide Yonekura, Eiji Tanaka, M Nakajima and Keiichi Hosaka : Restoration of a Microdont Using the Resin Composite Injection Technique With a Fully Digital Workflow: A Flexible 3D-printed Index With a Holding Clip., Operative Dentistry, 2023. (要約) Direct composite restorations are accepted as a treatment option for microdontia, which is a relatively prevalent condition that poses esthetic concerns. While free-hand composite placement is technique-sensitive and time-consuming, the resin composite injection technique is more straightforward and predictable. A fully digital workflow has been recently introduced, but the 3D-printed resin index is rigid and challenged by undercuts, as opposed to the silicone index. This case report presents a flexible 3D-printed resin index, which can accurately transfer the digitally simulated functional and esthetic form to the final restoration. In addition, a rigid holding clip was designed to stabilize the flexible index. (出版サイトへのリンク) ● Publication site (DOI): 10.2341/23-007 (文献検索サイトへのリンク) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 37503684 ● Search Scopus @ Elsevier (PMID): 37503684 ● Search Scopus @ Elsevier (DOI): 10.2341/23-007 (DOI: 10.2341/23-007, PubMed: 37503684)
6.	Ryoko Shioyasono, Atsushi Shioyasono, Ayami Ito, Kaoru Yoshinaga, S Kinjo, Keiichiro Watanabe, Masahiro Hiasa, N Takamaru and Eiji Tanaka : A patient with unilateral posterior crossbite treated with modified unilateral surgically-assisted rapid maxillary expansion., American Journal of Orthodontics and Dentofacial Orthopedics (AJO-DO), Vol.3, No.2, 149-162, 2023.
7.	Toshinori Okawa, Susumu Abe, Keiichiro Watanabe, Kouhei Kamoi, Kenji Oka, Chie Wada -Mihara, Akira Imakiire, Taeko Masuda, Nanoha Matsumoto, Chihiro Shinohara and Fumiaki Kawano : Possibility and Future of Intraoral Scanner Application to Change the Method of Taking Impressions, Journal of Oral Health and Biosciences, Vol.35, No.2, 33-38, 2023. (徳島大学機関リポジトリ) ● Metadata: 118166 (出版サイトへのリンク) ● Publication site (DOI): 10.20738/johb.35.2_33 (文献検索サイトへのリンク) ● Search Scopus @ Elsevier (DOI): 10.20738/johb.35.2_33 (徳島大学機関リポジトリ: 118166, DOI: 10.20738/johb.35.2_33)
8.	鴨居浩平, 大山正弘, 渡邉佳一郎, 中川竜二, 森達夫, 小山智史, 郷司彩, 福田潤弥, 富永賢 : ピエール・ロバン症候群乳児における維持と調整機構を付与したPre-epiglottic baton plateの製作, 日本口腔顎顔面技工学会会誌, Vol.22, No.1, 9-15, 2022年.
9.	Ryoko Shioyasono, Kaoru Yoshinaga, Atsushi Shioyasono, Ayami Ito, Keiichiro Watanabe, Masahiro Hiasa, Shinya Horiuchi and Eiji Tanaka : Nonsurgical orthodontic treatment for a patient with Sotos syndrome., American Journal of Orthodontics and Dentofacial Orthopedics (AJO-DO), Vol.163, No.3, 426-442, 2022. (要約) Sotos syndrome is a genetic disorder characterized by overgrowth in childhood, specific facial manifestations, advanced bone age, and mental retardation. The purpose of this article is to describe the nonsurgical orthodontic treatment of a 10-year-old boy with a skeletal mandibular protrusion, unilateral posterior crossbite, and Sotos syndrome. After maxillary lateral expansion, the skeletal Class III relationship with an anterior crossbite improved because of mandibular clockwise rotation, whereas the facemask had a marginal effect. After growth at 16 years, he had a skeletal Class I relationship, and thus, conventional orthodontic treatment with preadjusted edgewise appliances was initiated. After 41 months of multibracket treatment, acceptable occlusion with a functional Class I relationship was obtained. One year postretention, few changes in occlusion and facial features were observed. Our results demonstrate that considering the maxillofacial vertical growth during the peripubertal period associated with Sotos syndrome, more attention should be paid to the early orthopedic treatment with the facemask and/or chincap. (キーワード) 男性 (male) / Humans / 子ども (children) / Malocclusion, Angle Class III / Sotos Syndrome / Cephalometry / Malocclusion / Mandible / Palatal Expansion Technique / Extraoral Traction Appliances / Maxilla (徳島大学機関リポジトリ) ● Metadata: 118746 (出版サイトへのリンク) ● Publication site (DOI): 10.1016/j.ajodo.2021.11.021 (文献検索サイトへのリンク) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 36437146 ● Search Scopus @ Elsevier (PMID): 36437146 ● Search Scopus @ Elsevier (DOI): 10.1016/j.ajodo.2021.11.021 (徳島大学機関リポジトリ: 118746, DOI: 10.1016/j.ajodo.2021.11.021, PubMed: 36437146)
10.	Joshua M. Ferraro, Sanghee Lee, Keiichiro Watanabe, Tai-Hsien Wu, Do-Gyoon Kim, Ching-Chang Ko, Eiji Tanaka, Motoyoshi Mitsuru and Toru Deguchi : Accuracy of three-dimensional printed models derived from cone-beam computed tomography, The Angle Orthodontist, Vol.92, No.6, 722-727, 2022. (要約) To determine the accuracy of three-dimensional (3D) printed models fabricated from cone-beam computed tomography (CBCT) scans of human mandibular dry skulls in comparison with models derived from intraoral scanner (IOS) data. Six human mandibular dry skulls were scanned by IOS and CBCT. Digital models (DMs) constructed from the IOS and CBCT data were fabricated physically using a 3D printer. The width and thickness of individual teeth and intercanine and molar widths were measured using a digital caliper. The accuracy of the DMs was compared between IOS and CBCT. Paired t-tests were used for intergroup comparisons. All intraclass correlation coefficient values for the three measurements (mesial-distal, buccal-lingual, width) exceeded 0.9. For the mandibular teeth, there were significant discrepancies in model accuracy between the IOS (average discrepancies of 0.18 ± 0.08 mm and 0.16 ± 0.12 mm for width and thickness, respectively) and CBCT (0.28 ± 0.07 mm for width, 0.37 ± 0.2 mm for thickness; P < .01). Intercanine (P = .38) and molar widths (P = .41) showed no significant difference between groups. There was a statistically significant difference in the accuracy of DMs obtained from CBCT and IOS; however, this did not seem to result in any important clinical difference. CBCT could be routinely used as an orthodontic diagnostic tool and for appliance construction. (キーワード) 3D printed model / CBCT (徳島大学機関リポジトリ) ● Metadata: 117664 (出版サイトへのリンク) ● Publication site (DOI): 10.2319/021122-128.1 (文献検索サイトへのリンク) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 35852459 ● Search Scopus @ Elsevier (PMID): 35852459 ● Search Scopus @ Elsevier (DOI): 10.2319/021122-128.1 (徳島大学機関リポジトリ: 117664, DOI: 10.2319/021122-128.1, PubMed: 35852459)
11.	重田南, 渡邉佳一郎, 森浩喜, 田中栄二 : 犬歯の埋伏による重度歯根吸収を呈した上顎切歯に対して下顎小臼歯の自家移植を行った歯性上顎前突の一治験例, 中·四国矯正歯科学会雑誌, Vol.34, No.1, 53-64, 2022年. (徳島大学機関リポジトリ) ● Metadata: 118827 (徳島大学機関リポジトリ: 118827)
12.	Jie Liu, Keiichiro Watanabe, Shareef M. Dabdoub, Beth S.Lee and Do-Gyoon Kim : Site-specific characteristics of bone and progenitor cells in control and ovariectomized rats, Bone, Vol.163, 116501, 2022. (要約) One-third of postmenopausal women experience at least one osteoporotic bone fracture in their lifetime that occurs spontaneously or from low-impact events. However, osteoporosis-associated jaw bone fractures are extremely rare. It was also observed that jaw bone marrow stem cells (BMSCs) have a higher capacity to form mineralized tissues than limb BMSCs. At present, the underlying causes and mechanisms of variations between jaw bone and limb bone during postmenopause are largely unknown. Thus, the objective of the current study was to examine the site-specific effects of estrogen deficiency using comprehensive analysis of bone quantity and quality, and its association with characterization of cellular components of bone. Nine rats (female, 6 months old) for each bilateral sham and ovariectomy (OVX) surgery were obtained and maintained for 2 months after surgery. A hemi-mandible and a femur from each rat were characterized for parameters of volume, mineral density, cortical and trabecular morphology, and static and dynamic mechanical analysis. Another set of 5 rats (female, 9 months old) was obtained for assays of BMSCs. Following cytometry to identify BMSCs, bioassays for proliferation, and osteogenic, adipogenic, chondrogenic differentiation, and cell mitochondrial stress tests were performed. In addition, mRNA expression of BMSCs was analyzed. OVX decreased bone quantity and quality (mineral content, morphology, and energy dissipation) of femur while those of mandible were not influenced. Cellular assays demonstrated that mandible BMSCs showed greater differentiation than femur BMSCs. Gene ontology pathway analysis indicated that the mandibular BMSCs showed most significant differential expression of genes in the regulatory pathways of osteoblast differentiation, SMAD signaling, cartilage development, and glucose transmembrane transporter activity. These findings suggested that active mandibular BMSCs maintain bone formation and mineralization by balancing the rapid bone resorption caused by estrogen deficiency. These characteristics likely help reduce the risk of osteoporotic fracture in postmenopausal jawbone. (出版サイトへのリンク) ● Publication site (DOI): 10.1016/j.bone.2022.116501 (文献検索サイトへのリンク) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 35872108 ● Search Scopus @ Elsevier (PMID): 35872108 ● Search Scopus @ Elsevier (DOI): 10.1016/j.bone.2022.116501 (DOI: 10.1016/j.bone.2022.116501, PubMed: 35872108)
13.	Takuma Sakamaki, Keiichiro Watanabe, Akihiko Iwasa, Toru Deguchi, Shinya Horiuchi and Eiji Tanaka : Thread shape, cortical bone thickness, and magnitude and distribution of stress caused by the loading of orthodontic miniscrews: finite element analysis., Scientific Reports, Vol.12, No.1, 2022. (要約) Cortical bone thickness is assumed to be a major factor regulating miniscrew stability. We investigated stress distribution in two miniscrews with different thread shapes (type A and B) and in cortical bone of three different thicknesses using three-dimensional (3D) finite element (FE) models. More specifically, 3D FE models of two different miniscrews were created and placed obliquely or vertically into a cylindrical bone model representing different cortical bone thicknesses. When force was applied to the miniscrew, the stress distribution on the screw surface and in the peri-implant bone was assessed using FE methodology. Miniscrew safety was evaluated using a modified Soderberg safety factor. Screw head displacement increased with a decrease in cortical bone thickness, irrespective of screw type. The smallest minimum principal stresses on the screw surfaces remained constant in type A miniscrews on changes in cortical bone thickness. Minimum principal stresses also appeared on the cortical bone surface. Lower absolute values of minimum principal stresses were seen in type A miniscrews when placed vertically and with upward traction in obliquely placed type B miniscrews. Both miniscrews had acceptable safety factor values. Taken together, orthodontists should select and use the suitable miniscrew for each patient in consideration of bone properties. (キーワード) Cortical Bone / 有限要素解析 (finite element analysis) / Humans / Orthodontic Anchorage Procedures / Orthodontic Appliance Design / Stress, Mechanical / チタン (titanium) (徳島大学機関リポジトリ) ● Metadata: 117262 (出版サイトへのリンク) ● Publication site (DOI): 10.1038/s41598-022-16662-w (文献検索サイトへのリンク) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 35859046 ● Search Scopus @ Elsevier (PMID): 35859046 ● Search Scopus @ Elsevier (DOI): 10.1038/s41598-022-16662-w (徳島大学機関リポジトリ: 117262, DOI: 10.1038/s41598-022-16662-w, PubMed: 35859046)
14.	Bobby Mitchell, Jie Liu, Sanghee Lee, Keiichiro Watanabe, Do-Gyoon Kim, Henry W Fields, Xiaohan Guo, Lu Wei-En and Toru Deguchi : Quantitative evaluation of training method in placing miniscrews in orthodontic graduate program, Progress in Orthodontics, Vol.23, No.1, 33, 2022. (要約) The purpose of this study was to assess the effectiveness of training residents in an orthodontic program in the placement of miniscrews by using cone beam computed tomography (CBCT) images. A total of 90 miniscrews were placed in 15 pig mandibles over a 3-year period by 15 first-year orthodontic residents. Miniscrews were divided into three groups (Control group: no radiographs; 2D group: placement with 2D radiographs; CBCT group: placement with CBCT). Proximity of the miniscrew to the neighboring root was measured. The miniscrew success rate was examined in the graduate clinic from 2015 to 2021. The percentage of root contact for each group was: 36.7% (11/30), 20.0% (6/30), 0% (0/30), for the Control, 2D, and CBCT groups, respectively. The CBCT group was significantly different from the Control and 2D groups (p < 0.05). For root proximity, the miniscrews were significantly closer to the roots in the Control (p < 0.001) and 2D (p < 0.001) groups compared with the CBCT group. No significant difference was observed between the Control and 2D groups (p = 0.80). There was no significant difference among the years in the miniscrew success rate. Training the residents in an orthodontic graduate program using CBCT may be helpful to avoid root damage and to decrease the miniscrew failure rate. (キーワード) Animals / Bone Screws / Cone-Beam Computed Tomography / Mandible / Orthodontic Anchorage Procedures / Swine (出版サイトへのリンク) ● Publication site (DOI): 10.1186/s40510-022-00430-7 (文献検索サイトへのリンク) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 36184724 ● Summary page in Scopus @ Elsevier: 2-s2.0-85139102664 (DOI: 10.1186/s40510-022-00430-7, PubMed: 36184724, Elsevier: Scopus)
15.	Keiichiro Watanabe, Bobby Mitchell, Takuma Sakamaki, Yuzo Hirai, Do-Gyoon Kim, Toru Deguchi, Masakazu Suzuki, Kanji Ueda and Eiji Tanaka : Mechanical stability of orthodontic miniscrew depends on a thread shape., Journal of Dental Sciences, Vol.17, No.3, 1244-1252, 2022. (要約) The MIT, RT, TR and K of type C miniscrew were significantly greater than those of type A and B miniscrews when the miniscrews were placed in the thinner artificial bone. Furthermore, the TR value of type C miniscrew was more than 1, indicating the MRT value was larger than the MIT value in the novel miniscrew. The values of K∗ and tan (徳島大学機関リポジトリ) ● Metadata: 117257 (出版サイトへのリンク) ● Publication site (DOI): 10.1016/j.jds.2021.11.010 (文献検索サイトへのリンク) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 35784157 ● Search Scopus @ Elsevier (PMID): 35784157 ● Search Scopus @ Elsevier (DOI): 10.1016/j.jds.2021.11.010 (徳島大学機関リポジトリ: 117257, DOI: 10.1016/j.jds.2021.11.010, PubMed: 35784157)
16.	Keiichiro Watanabe, Lee Sanghee, Lee Damian, Zheng Fengyuan, Kyung Hee-Moon, Kim Do-Gyoon and Deguchi Toru : Evaluation of clinical parameters for the stability of 2 types of miniscrews, American Journal of Orthodontics and Dentofacial Orthopedics (AJO-DO), Vol.161, No.3, 437-444, 2022. (要約) The purpose of this research was to compare insertion techniques and effects on mechanical and clinical parameters between 2 types of miniscrews. Forty-four consecutive patients whose orthodontic treatment involved the use of miniscrews (miniscrew A [MA] and miniscrew B [MB]) for anchorage were included in this study. Miniscrews were placed with predrilling or self-drilling; peak maximum insertion torque (MIT) and Periotest values were measured. Cone-beam computed tomography was performed after the insertion of miniscrews and root proximity determination; cortical bone thickness was also analyzed. Periotest values were measured after the application of orthodontic force. Self-drilling produced higher Periotest values (P <0.01) for MA and higher MIT (P <0.01) for MB with closer root proximity (P <0.05). MB had higher MIT and Periotest values with drilling compared with MA (P <0.05); MB also showed closer root proximity (P <0.05). Successful miniscrews had lower MIT (P <0.05) for MB and lower Periotest values (P <0.01) for both MA and MB, with significantly more distant root proximity (P <0.01). Self-drilling produced higher Periotest values at the time of placement (P <0.01) and after 4 weeks (P <0.05) in MA. Drilling produced higher Periotest values for MB at the time of placement (P <0.05). MIT had positive correlations with Periotest values for MB with self-drilling (P <0.01) and with root proximity for MA with drilling (P <0.01). Periotest values had negative correlations with root proximity for MA and the MB group with drilling (P <0.01). For miniscrews with larger diameters, higher MIT may result in more mobility (higher Periotest values). Drilling can avoid root contact and enhance primary stability, thus producing lower Periotest values. (キーワード) 臨床矯正歯科学 (clinical orthodontics) (出版サイトへのリンク) ● Publication site (DOI): 10.1016/j.ajodo.2020.09.035 (文献検索サイトへのリンク) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 34799196 ● Search Scopus @ Elsevier (PMID): 34799196 ● Search Scopus @ Elsevier (DOI): 10.1016/j.ajodo.2020.09.035 (DOI: 10.1016/j.ajodo.2020.09.035, PubMed: 34799196)
17.	Shinya Horiuchi, Hiroko Sato, Akihiko Iwasa, Aki Ichihara, Hirofumi Tenshin, Keiichiro Watanabe, Masahiro Hiasa, Ichiro Hashimoto and Eiji Tanaka : Long-term Management of a Patient with Apert Syndrome., The Journal of Contemporary Dental Practice, Vol.22, No.10, 1184-1190, 2021. (要約) The two-stage operation combining early distraction osteogenesis and postgrowth orthognathic surgery proves to be an effective therapy for correcting midfacial hypoplasia and skeletal mandibular protrusion caused by Apert syndrome. (キーワード) Acrocephalosyndactylia / Adolescent / Adult / Cephalometry / Humans / Infant / Male / Open Bite / Osteogenesis, Distraction / Osteotomy, Le Fort / Young Adult (徳島大学機関リポジトリ) ● Metadata: 117255 (文献検索サイトへのリンク) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 35197388 ● Search Scopus @ Elsevier (PMID): 35197388 (徳島大学機関リポジトリ: 117255, PubMed: 35197388)
18.	Yuzo Hirai, Keiichiro Watanabe, Toru Deguchi, Kanji Ueda, Kenichi Hamada and Eiji Tanaka : Influence of insertion depth on stress distribution in orthodontic miniscrew and the surrounding bone by finite element analysis., Dental Materials Journal, Vol.40, No.5, 1270-1276, 2021. (要約) We aimed to elucidate stress distribution in miniscrews and the surrounding bone when miniscrews inserted at different depths were implanted vertically or obliquely. The distributions of the equivalent stress on the screw surface and the minimum principal stress in the surrounding bone were calculated using finite element models. When the miniscrews were inserted vertically and obliquely, screw head displacement, greatest equivalent stress on the miniscrew surface, and absolute value of minimum principal stresses in the surrounding bone decreased with increasing insertion depth. Stresses in the obliquely inserted miniscrew with upward traction were smaller than in other insertion conditions, irrespective of insertion depth. With the application of orthodontic force, stress distribution around the miniscrew and surrounding bone is closely related to the insertion depth and insertion angle, which mutually affect each other. In particular, the obliquely inserted miniscrew with upward traction might be the most secure against screw failure and fracture. (徳島大学機関リポジトリ) ● Metadata: 116714 (出版サイトへのリンク) ● Publication site (DOI): 10.4012/dmj.2020-400 (文献検索サイトへのリンク) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 34193725 ● Search Scopus @ Elsevier (PMID): 34193725 ● Search Scopus @ Elsevier (DOI): 10.4012/dmj.2020-400 (徳島大学機関リポジトリ: 116714, DOI: 10.4012/dmj.2020-400, PubMed: 34193725)
19.	吉永薫, 塩屋園玲子, 渡邉佳一郎, 日浅雅博, 堀内信也, 田中栄二 : 歯科矯正用アンカースクリューの導入に伴う治療方針の変化(第一報) 抜歯・非抜歯および抜歯部位の判定に関する検討, 中·四国矯正歯科学会雑誌, Vol.33, No.1, 19-28, 2021年. (要約) 【目的】近年，歯科矯正用アンカースクリュー(以降アンカーと明記する)の普及により，臼歯の固定や移動が容易に行えるようになり，抜歯，非抜歯，抜歯部位の選択についても変化が起きている．今回，アンカーの導入前後での治療方針の変化について，とくに臼歯抜歯の適応に関する調査を行ったので報告する．【方法】徳島大学病院矯正歯科を受診した初診時年齢12歳以上の患者を対象とし，2002年以前にマルチブラケット治療の診断を受けた100名(Pre群)と2008年以降に診断を受けた100名(Post群)を無作為に抽出した．先天性疾患および歯牙欠損症例，顎変形症は除外した．診断内容における臼歯抜歯(第三大臼歯は除く)の有無，抜歯部位等に関する比較検討を行った．【結果および考察】Pre群とPost群の間で抜歯症例数および抜歯部位に違いは認められなかった．一方，skeletal Class IIの症例はPre群では上顎片顎小臼歯抜歯によるカムフラージュ治療が多かったのに対し，Post群ではその割合は減少していた．また，skeletal Class IIIの症例ではアンカーを用いた非抜歯治療の割合が増加していた．High mandibular plane angle caseにおいてはアンカーの使用により，上顎第一大臼歯の挺出防止ならびに圧下が可能となり上下顎第一小臼歯を抜去する割合が増えた．【結論】アンカー導入で，臼歯の移動や挺出の防止および圧下が可能となり抜歯部位の選択基準に変化が生じたと考えられた．(著者抄録) (キーワード) 下顎骨上顎骨小臼歯(外科的療法) 抜歯不正咬合-アングルI級(治療) 不正咬合-アングルII級(治療) 不正咬合-アングルIII級(治療) 治療成績歯科矯正用固定源埋込みヒト歯学
20.	Ayami Ito, Kazuna Tachiki, Ryoko Shioyasono, Mohannad Ashtar, Keiichiro Watanabe, Masahiro Hiasa and Eiji Tanaka : Hemifacial Microsomia Caused by First and Second Brachial Arch Syndrome Treated with Orthodontic Approach: A Case Report., The Journal of Contemporary Dental Practice, Vol.21, No.10, 1189-1195, 2020. (要約) This report proposes an efficacy of conventional orthodontic treatment for growing patients with hemifacial microsomia involved in the FSBAS. (キーワード) Child / Dental Occlusion / Facial Asymmetry / 女性 (female) / Goldenhar Syndrome / Humans / 小児 (infant) / Mandible / Maxilla (徳島大学機関リポジトリ) ● Metadata: 116453 (出版サイトへのリンク) ● Publication site (DOI): 10.5005/JP-JOURNALS-10024-2957 (文献検索サイトへのリンク) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 33686045 ● Summary page in Scopus @ Elsevier: 2-s2.0-85099979923 (徳島大学機関リポジトリ: 116453, DOI: 10.5005/JP-JOURNALS-10024-2957, PubMed: 33686045, Elsevier: Scopus)
21.	清水宗, 堀内信也, 森浩喜, 天眞寛文, 岩浅亮彦, 渡邉佳一郎, 高木豊明, 田中栄二 : 徳島大学病院矯正歯科における保険診療に関する実態調査-先天性疾患における裂奇形の併発について, 中·四国矯正歯科学会雑誌, Vol.32, No.1, 87-92, 2020年. (要約) 矯正歯科治療に健康保険が導入されて約40年が経過し，唇顎口蓋裂と顎変形症の他に2018年現在53項目が保険治療の対象になっている．今回，我々は当科における矯正歯科治療の保険適用患者の実態を調査し，特に唇顎口蓋裂と他の先天性疾患との関連性について臨床統計学的検討を行ったので報告する．徳島大学病院病院情報システム・データウェアハウスを用い，2008年1月から2018年12月までの11年間に当院矯正歯科を受診した患者から保険治療を受けている患者を抽出し，顎変形症単独症例を除く先天性疾患患者について，電子カルテ全文検索システムを用いて臨床統計学的検討を行った．研究対象期間に当科にて保険治療を受けた矯正患者は345人で，そのうち，本研究対象患者は，顎変形症単独症例を除く207人であった．患者の内訳は，裂奇形を主徴候とする症例が全体の5割を占め最も多く，次いで，6歯以上の先天性部分性無歯症，ゴールデンハー症候群(鰓弓異常症を含む)，ダウン症候群の順であった．また，症候性疾患の中で裂奇形の併発は，ピエール・ロバン症候群，ダウン症候群，ゴールデンハー症候群の順に多く，その裂型は，口蓋裂(軟口蓋裂を含む)，唇顎口蓋裂，唇裂の順に多かった．以上のことから，当病院は裂奇形を併発した先天性疾患への専門的な対応が不可欠であり，希少疾患にも柔軟に対応できるよう複数の診療科，職種による診療科の枠組みを超えたチーム医療体制の構築が必要であることが示唆された． (キーワード) 先天性疾患 / 口唇裂・口蓋裂 / 臨床統計学的調査 / 合併症 (徳島大学機関リポジトリ) ● Metadata: 116914 (文献検索サイトへのリンク) ● CiNii @ 国立情報学研究所 (CRID): 1050010457800163712 (徳島大学機関リポジトリ: 116914, CiNii: 1050010457800163712)
22.	Keiichiro Watanabe, Samantha Lewis, Xiaohan Guo, Ai Ni, S Beth Lee, Toru Deguchi and Do-Gyoon Kim : Regional variations of jaw bone characteristics in an ovariectomized rat model., Journal of the Mechanical Behavior of Biomedical Materials, Vol.110, 2020. (キーワード) Animals / Bone Density / Female / Humans / Mandible / Ovariectomy / Rats / Rats, Sprague-Dawley / X-Ray Microtomography (出版サイトへのリンク) ● Publication site (DOI): 10.1016/j.jmbbm.2020.103952 (文献検索サイトへのリンク) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 32957244 ● Search Scopus @ Elsevier (PMID): 32957244 ● Search Scopus @ Elsevier (DOI): 10.1016/j.jmbbm.2020.103952 (DOI: 10.1016/j.jmbbm.2020.103952, PubMed: 32957244)
23.	Andrea E. Tsatalis, Keiichiro Watanabe, Bobby Mitchell, Do-Gyoon Kim, Damian J. Lee, Fengyuan Zheng, Hee-Moon Kyung and Toru Deguchi : Mechanical and clinical evaluation of the effect of microscrew on root proximity and cortical bone thickness., European Journal of Orthodontics, Vol.42, No.2, 206-210, 2020. (要約) Primary stability is required for successful use of microscrew. This study investigated correlations among biomechanical, morphological, and clinical values in relationship to root contact and different placement locations. Thirty-three microscrews were placed between the molars (n = 18) or in the body of the mandible (n = 15) in three pigs. Insertion torque, Periotest, resonance frequency analysis (RFA), and static and dynamic stiffness were measured. Cone beam computed tomography was performed before and after the insertion of microscrews. Interproximal microscrews were divided into root contacted microscrews (n = 9) and non-root contact microscrews (n = 9). Factorial analysis of variance was conducted, with significance set at P < 0.05. A significant difference was observed between bodily and root contacted microscrews in Periotest, RFA, static and dynamic stiffness, Tan , and bone density (RFA, P = 0.045; all others, P < 0.001). A significant difference was observed between bodily and non-root contact microscrews in Periotest, RFA, and bone density (RFA, P = 0.025; all others, P < 0.001). A significant difference was observed in static (P = 0.01) and dynamic (P = 0.038) stiffness between microscrews with and without contact. Dynamic stiffness (P = 0.02) and Tan (P = 0.03) showed significant correlations with Periotest results only in bodily microscrews. Since a pig bone was used, some differences in the quality and quantity of the bone might be observed between humans. Stiffness values distinguished between microscrews with and without contact. Periotest and RFA results indicated that bodily microscrews were more stable than interproximal microscrews. Periotest and RFA may be useful with large, microscrews and/or in thick cortical bone, but further investigation is required to determine the stability of interproximal microscrews. (出版サイトへのリンク) ● Publication site (DOI): 10.1093/ejo/cjz017 (文献検索サイトへのリンク) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 31075176 ● Search Scopus @ Elsevier (PMID): 31075176 ● Search Scopus @ Elsevier (DOI): 10.1093/ejo/cjz017 (DOI: 10.1093/ejo/cjz017, PubMed: 31075176)
24.	H Zhang, M B. Chavez, T N. Kolli, M H. Tan, H Fong, E Y. Chu, Y Li, X Ren, Keiichiro Watanabe, D G. Kim and B L. Foster : Dentoalveolar Defects in the Mouse Model of X-linked Hypophosphatemia., Journal of Dental Research, Vol.99, No.4, 419-428, 2020. (要約) Mutations in cause X-linked hypophosphatemia (XLH), a form of hypophosphatemic rickets. ( mutant) mice recapitulate the XLH phenotype. Dental disorders are prevalent in individuals with XLH; however, underlying dentoalveolar defects remain incompletely understood. We analyzed mouse dentoalveolar defects at 42 and 90 d postnatal to comparatively define effects of XLH on dental formation and function. mRNA was expressed by odontoblasts (dentin), osteocytes (bone), and cementocytes (cellular cementum) in wild-type (WT) mice. Enamel density was unaffected, though enamel volume was significantly reduced in mice. Dentin defects in molars were indicated histologically by wide predentin, thin dentin, and extensive interglobular dentin, confirming micro-computed tomography (micro-CT) findings of reduced dentin volume and density. Acellular cementum was thin and showed periodontal ligament detachment. Mechanical testing indicated dramatically altered periodontal mechanical properties in versus WT mice. mandibles demonstrated expanded alveolar bone with accumulation of osteoid, and micro-CT confirmed decreased bone volume fraction and alveolar bone density. Cellular cementum area was significantly increased in versus WT molars owing to accumulation of hypomineralized cementoid. Histology, scanning electron microscopy, and nanoindentation revealed hypomineralized "halos" surrounding cementocyte and osteocyte lacunae. Three-dimensional micro-CT analyses confirmed larger cementocyte/osteocyte lacunae and significantly reduced perilacunar mineral density. While long bone and alveolar bone osteocytes in mice overexpressed fibroblast growth factor 23 (), its expression in molars was much lower, with cementocyte expression particularly low. Expression and distribution of other selected markers were disturbed in versus WT long bone, alveolar bone, and cementum, including osteocyte/cementocyte marker dentin matrix protein 1 (). This study reports for the first time a quantitative analysis of the mouse dentoalveolar phenotype, including all mineralized tissues. Novel insights into cellular cementum provide evidence for a role for cementocytes in perilacunar mineralization and cementum biology. (出版サイトへのリンク) ● Publication site (DOI): 10.1177/0022034520901719 (文献検索サイトへのリンク) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 31977267 ● Search Scopus @ Elsevier (PMID): 31977267 ● Search Scopus @ Elsevier (DOI): 10.1177/0022034520901719 (DOI: 10.1177/0022034520901719, PubMed: 31977267)
25.	市原亜起, 堀内信也, 小笠原直子, 森浩喜, 天知良太, 渡邉佳一郎, 木内奈央, 泰江章博, 田中栄二 : 徳島大学病院矯正歯科における口唇裂・口蓋裂患者の永久歯の歯数異常に関する調査, 中·四国矯正歯科学会雑誌, Vol.30, No.1, 51-58, 2018年. (徳島大学機関リポジトリ) ● Metadata: 116911 (徳島大学機関リポジトリ: 116911)
26.	Nao Kinouchi, Shinya Horiuchi, Akihiro Yasue, Yuko Kuroda, Nobuhiko Kawai, Keiichiro Watanabe, Takashi Izawa, Ichiro Hashimoto, H Ali Hassan and Eiji Tanaka : Effectiveness of presurgical nasoalveolar molding therapy on unilateral cleft lip nasal deformity., Saudi Medical Journal, Vol.39, No.2, 169-178, 2018. (要約) To evaluate the effectiveness of pre-surgical nasoalveolar molding (PNAM) in patients with unilateral cleft lip nasal deformities. Methods: This was a retrospective study involving 29 patients with unilateral cleft lip and palate defects, of whom 13 were treated with palatal devices with nasal stents (PNAM group) and 16 were treated with palatal devices without nasal stents or surgical tapes (control group). Submental oblique photographs and orthodontic models were longitudinally obtained at the initial visit (T1) and immediately before (T2) and after cheiloplasty (T3). Asymmetry of the external nose, degree of columellar shifting, nasal tip/ala nose ratio, nasal base angle, interalveolar gap, and the sagittal difference in the alveolar gap were measured. The study was conducted in the Orthodontic Clinic at Tokushima University Hospital, Tokushima, Japan between 1997 and 2012. Results: At T1, there were no significant intergroup differences in the first 4 asymmetry parameters. At T2, the PNAM group showed a significant improvement in all values compared to the control group. At T3, the PNAM group showed significant improvement in nasal asymmetry and columellar shifting. Model analysis showed significantly greater changes in the inter-alveolar gap and the sagittal difference of the alveolar cleft gap from T1 to T2 in the PNAM group. Conclusion: The use of PNAM is indispensable for pre-surgical orthodontic treatment at the early postnatal age. (徳島大学機関リポジトリ) ● Metadata: 113505 (出版サイトへのリンク) ● Publication site (DOI): 10.15537/smj.2018.2.21020 (文献検索サイトへのリンク) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 29436566 ● Search Scopus @ Elsevier (PMID): 29436566 ● Search Scopus @ Elsevier (DOI): 10.15537/smj.2018.2.21020 (徳島大学機関リポジトリ: 113505, DOI: 10.15537/smj.2018.2.21020, PubMed: 29436566)
27.	Takafumi Susami, Toshihiko Fukawa, Haruyo Miyazaki, Teruo Sakamoto, Tadashi Morishita, Yoshiaki Sato, Yoshiaki Kinno, Kazuyuki Kurata, Keiichiro Watanabe, Toshikazu Asahito and Isao Saito : A Survey of Orthodontic Treatment in Team Care for Patients With Syndromic Craniosynostosis in Japan., Cleft Palate-Craniofacial Journal, Vol.55, No.4, 479-486, 2018. (要約) To understand the actual condition of orthodontic treatment in team care for patients with syndromic craniosynostosis (SCS) in Japan. A nationwide collaborative survey. Twenty-four orthodontic clinics in Japan. A total of 246 patients with SCS. Treatment history was examined based on orthodontic records using common survey sheets. Most patients first visited the orthodontic clinic in the deciduous or mixed dentition phase. Midface advancement was performed without visiting the orthodontic clinic in about a quarter of the patients, and more than a half of the patients underwent "surgery-first" midface advancement. First-phase orthodontic treatment was carried out in about a half of the patients, and maxillary expansion and protraction were performed. Tooth extraction was required in about two-thirds of patients, and the extraction of maxillary teeth was required in most patients. Tooth abnormalities were found in 37.8% of patients, and abnormalities of maxillary molars were frequently (58.3%) found in patients who had undergone midface surgery below the age of 6 years. Many patients underwent "surgery-first" midface advancement, and visiting the orthodontic clinic at least before advancement was considered desirable. First-phase orthodontic treatment should be performed considering the burden of care. Midface advancement below the age of 6 years had a high risk of injury to the maxillary molars. This survey is considered useful for improving orthodontic treatment in team care of patients with SCS. (キーワード) Adolescent / Child / Child, Preschool / Combined Modality Therapy / Craniosynostoses / Female / Humans / Infant / Infant, Newborn / Japan / Male / Orthodontics, Corrective / Orthognathic Surgical Procedures / Palatal Expansion Technique / Patient Care Team / Surveys and Questionnaires / Tooth Extraction / Treatment Outcome / Young Adult (出版サイトへのリンク) ● Publication site (DOI): 10.1177/1055665617747703 (文献検索サイトへのリンク) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 29351022 ● Search Scopus @ Elsevier (PMID): 29351022 ● Search Scopus @ Elsevier (DOI): 10.1177/1055665617747703 (DOI: 10.1177/1055665617747703, PubMed: 29351022)
28.	Hirofumi Tenshin, Jumpei Teramachi, Asuka Oda, Ryota Amachi, Masahiro Hiasa, Ariunzaya Bat-Erdene, Keiichiro Watanabe, Masami Iwasa, Takeshi Harada, Shiroh Fujii, Kumiko Kagawa, Kimiko Sogabe, Shingen Nakamura, Hirokazu Miki, Kiyoe Kurahashi, Sumiko Yoshida, Kenichi Aihara, Itsuro Endo, Eiji Tanaka, Toshio Matsumoto and Masahiro Abe : TAK1 inhibition subverts the osteoclastogenic action of TRAIL while potentiating its antimyeloma effects., Blood Advances, Vol.1, No.24, 2124-2137, 2017. (要約) Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) agonists induce tumor-specific apoptosis indicating that they may be an attractive therapeutic strategy against cancers, including multiple myeloma (MM). Osteoclastogenesis is highly induced in MM, which in turn enhances MM growth, thereby forming a vicious cycle between MM tumor expansion and bone destruction. However, the effects of TRAIL on MM-enhanced osteoclastogenesis remain largely unknown. Here, we show that TRAIL induced apoptosis in MM cells, but not in osteoclasts (OCs), and that it rather facilitated receptor activator of NF-B ligand-induced osteoclastogenesis along with upregulation of cellular FLICE inhibitory protein (c-FLIP). TRAIL did not induce death-inducing signaling complex formation in OCs, but formed secondary complex (complex II) with the phosphorylation of transforming growth factor -activated kinase-1 (TAK1), and thus activated NF-B signaling. c-FLIP knockdown abolished complex II formation, thus permitting TRAIL induction of OC cell death. The TAK1 inhibitor LLZ1640-2 abrogated the TRAIL-induced c-FLIP upregulation and NF-B activation, and triggered TRAIL-induced caspase-8 activation and cell death in OCs. Interestingly, the TRAIL-induced caspase-8 activation caused enzymatic degradation of the transcription factor Sp1 to noticeably reduce c-FLIP expression, which further sensitized OCs to TRAIL-induced apoptosis. Furthermore, the TAK1 inhibition induced antiosteoclastogenic activity by TRAIL even in cocultures with MM cells while potentiating TRAIL's anti-MM effects. These results demonstrated that osteoclastic lineage cells use TRAIL for their differentiation and activation through tilting caspase-8-dependent apoptosis toward NF-B activation, and that TAK1 inhibition subverts TRAIL-mediated NF-B activation to resume TRAIL-induced apoptosis in OCs while further enhancing MM cell death in combination with TRAIL. (徳島大学機関リポジトリ) ● Metadata: 111724 (出版サイトへのリンク) ● Publication site (DOI): 10.1182/bloodadvances.2017008813 (文献検索サイトへのリンク) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 29296860 ● Search Scopus @ Elsevier (PMID): 29296860 ● Search Scopus @ Elsevier (DOI): 10.1182/bloodadvances.2017008813 (徳島大学機関リポジトリ: 111724, DOI: 10.1182/bloodadvances.2017008813, PubMed: 29296860)
29.	天知良太, 渡邉佳一郎, 泰江章博, 川合暢彦, 堀内信也, 田中栄二 : 歯科矯正用アンカースクリューを用いて上下歯列遠心移動を行った三年保定症例, 中·四国矯正歯科学会雑誌, Vol.29, No.1, 37-48, 2017年. (徳島大学機関リポジトリ) ● Metadata: 115852 (徳島大学機関リポジトリ: 115852)
30.	Ryota Amachi, Masahiro Hiasa, Jumpei Teramachi, Takeshi Harada, Asuka Oda, Shingen Nakamura, Derek Hanson, Keiichiro Watanabe, Shiroh Fujii, Hirokazu Miki, Kumiko Kagawa, Masami Iwasa, Itsuro Endo, Takeshi Kondo, Sumiko Yoshida, Ken-ichi Aihara, Kiyoe Kurahashi, Yoshiaki Kuroda, Hideaki Horikawa, Eiji Tanaka, Masahiro Abe and Toshio Matsumoto : A vicious cycle between acid sensing and survival signaling in myeloma cells: acid-induced epigenetic alteration., Oncotarget, Vol.7, No.43, 70447-70461, 2016. (要約) Myeloma (MM) cells and osteoclasts are mutually interacted to enhance MM growth while creating acidic bone lesions. Here, we explored acid sensing of MM cells and its role in MM cell response to acidic conditions. Acidic conditions activated the PI3K-Akt signaling in MM cells while upregulating the pH sensor transient receptor potential cation channel subfamily V member 1 (TRPV1) in a manner inhibitable by PI3K inhibition. The acid-activated PI3K-Akt signaling facilitated the nuclear localization of the transcription factor Sp1 to trigger the expression of its target genes, including TRPV1 and HDAC1. Consistently, histone deacetylation was enhanced in MM cells in acidic conditions, while repressing a wide variety of genes, including DR4. Indeed, acidic conditions deacetylated histone H3K9 in a DR4 gene promoter and curtailed DR4 expression in MM cells. However, inhibition of HDAC as well as either Sp1 or PI3K was able to restore DR4 expression in MM cells suppressed in acidic conditions. These results collectively demonstrate that acid activates the TRPV1-PI3K-Akt-Sp1 signaling in MM cells while inducing HDAC-mediated gene repression, and suggest that a positive feedback loop between acid sensing and the PI3K-Akt signaling is formed in MM cells, leading to MM cell response to acidic bone lesions. (徳島大学機関リポジトリ) ● Metadata: 113048 (出版サイトへのリンク) ● Publication site (DOI): 10.18632/oncotarget.11927 (文献検索サイトへのリンク) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 27626482 ● Search Scopus @ Elsevier (PMID): 27626482 ● Search Scopus @ Elsevier (DOI): 10.18632/oncotarget.11927 (徳島大学機関リポジトリ: 113048, DOI: 10.18632/oncotarget.11927, PubMed: 27626482)
31.	MANSJUR KARIMA QURNIA, Shingo Kuroda, Takashi Izawa, Yuichi Maeda, Minami Sato, Keiichiro Watanabe, Shinya Horiuchi and Eiji Tanaka : The Effectiveness of Human Parathyroid Hormone and Low-Intensity Pulsed Ultrasound on the Fracture Healing in Osteoporotic Bones., Annals of Biomedical Engineering, 2016. (要約) Osteoporotic fracture has become a major public health problem, and until today, the treatments available are not satisfactory. While there is growing evidence to support the individual treatment of parathyroid hormone (PTH) administration and low-intensity pulsed ultrasound (LIPUS) exposure as respectively systemic and local therapies during osteoporotic fracture healing, their effects have not yet been investigated when introduced concurrently. This study aimed to evaluate the effects of combined treatment with PTH (1-34) and LIPUS on fracture healing in ovariectomized (OVX) rats. Thirty-two, 12-week-old female Sprague-Dawley rats were OVX to induce osteoporosis. After 12 weeks, the rats underwent surgery to create bilateral mid-diaphyseal fractures of proximal tibiae. All animals were randomly divided into 4 groups (n = 8 for each): control group as placebo, PTH group, LIPUS group, and combined group. PTH group had PTH administration at a dose of 30 μg/kg/day for 3 days/week for 6 weeks. LIPUS group received ultrasound 5 days/week for 20 min/day for 6 weeks and combined group had both PTH administration and LIPUS exposure for 6 weeks. Fracture healing was observed weekly by anteroposterior radiography and micro-CT. Five weeks after the fracture, the tibia were harvested to permit histological assessments and at week 6, for mechanical property of the fracture callus. Micro-CT showed that the PTH and combined groups exhibited significantly higher BMD and trabecular bone integrity than control group at weeks 4-6. Radiography, fracture healing score and mean callus area indicated that the combined group revealed better healing processes than the individual groups. Mechanically, bending moment to failure was significantly higher in LIPUS, PTH and combined groups than in control group. These data suggest that the combined treatment of PTH and LIPUS have been shown to accelerate fracture bone healing and enhance bone properties rather than single agent therapy, and may be considered as a treatment remedy for fracture healing in postmenopausal osteoporosis. (徳島大学機関リポジトリ) ● Metadata: 109959 (出版サイトへのリンク) ● Publication site (DOI): 10.1007/s10439-015-1533-y (文献検索サイトへのリンク) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 26795976 ● Summary page in Scopus @ Elsevier: 2-s2.0-84955254616 (徳島大学機関リポジトリ: 109959, DOI: 10.1007/s10439-015-1533-y, PubMed: 26795976, Elsevier: Scopus)
32.	篠原丈裕, 渡邉佳一郎, 森浩喜, 井澤俊, 堀内信也, 黒田晋吾, 谷本幸太郎, 田中栄二 : 顎関節内障を有する骨格性下顎前突症に対する矯正歯科治療の一治験例, 中·四国矯正歯科学会雑誌, Vol.27, No.1, 39-48, 2015年.
33.	Hirokazu Miki, Shingen Nakamura, A Oda, R Amachi, Keiichiro Watanabe, D Hanson, Jumpei Teramachi, Masahiro Hiasa, H Yagi, K Sogabe, M Takahashi, T Maruhashi, K Udaka, T Harada, Shiroh Fujii, A Nakano, Kumiko Kagawa, M Ri, S Iida, Shuji Ozaki, T Matsumoto and Masahiro Abe : Induction of endoplasmic reticulum stress by bortezomib sensitizes myeloma cells to DR5-mediated cell death, International Journal of Myeloma, Vol.5, No.1, 1-7, 2015. (要約) <p>TNF-related apoptosis-including ligand/Apo2 (TRAIL)-mediated immunotherapy is an attractive anti-tumor modality with high tumor specificity. In order to improve its therapeutic efficacy, we further need to implement a novel maneuver for sensitization of malignant cells to TRAIL. Bortezomib (BTZ), a novel anti-myeloma (MM) agent, potently induces endoplasmic reticulum (ER) stress to cause apoptosis. Here, we explored the roles of BTZ in the cytotoxicity of anti-TRAIL receptor agonistic antibodies against MM cells with special reference to ER stress. BTZ enhanced the expression of death receptor 5 (DR5) but not DR4 in MM cells at surface protein as well as mRNA levels. However, the DR5 expression was not affected by BTZ without ER stress induction in MM cells with a point mutation in a BTZ-binding proteasome β<sub>5</sub> subunit. Tunicamycin, an ER stress inducer, was able to enhance the DR5 expression even in the BTZ-resistant MM cells, suggesting the role of ER stress in up-regulation of DR5 expression. Interestingly, BTZ facilitated extrinsic caspase-mediated apoptosis by anti-DR5 agonistic antibody in MM cells along with reducing c-FLICE-like interleukin protein, a caspase 8 inhibitor. These results suggest that BTZ enhances DR5 expression and its downstream apoptotic signaling through ER stress to sensitize MM cells to TRAIL-mediated immunotherapy.</p> (キーワード) multiple myeloma / bortezomib / TRAIL / DR5 / ER stress (出版サイトへのリンク) ● Publication site (DOI): 10.57352/ijm.5.1_1 (文献検索サイトへのリンク) ● CiNii @ 国立情報学研究所 (CRID): 1390292815284471040 ● Search Scopus @ Elsevier (DOI): 10.57352/ijm.5.1_1 (DOI: 10.57352/ijm.5.1_1, CiNii: 1390292815284471040)
34.	Masahiro Hiasa, Jumpei Teramachi, A Oda, Ryota Amachi, T Harada, Shingen Nakamura, Hirokazu Miki, Shiroh Fujii, Kumiko Kagawa, Keiichiro Watanabe, Itsuro Endo, Y Kuroda, T Yoneda, Daisuke Tsuji, Michiyasu Nakao, Eiji Tanaka, Kenichi Hamada, Shigeki Sano, Kouji Itou, Toshio Matsumoto and Masahiro Abe : Pim-2 kinase is an important target of treatment for tumor progression and bone loss in myeloma., Leukemia, 2014. (要約) Pim-2 kinase is overexpressed in multiple myeloma (MM) cells to enhance their growth and survival, and regarded as a novel therapeutic target in MM. However, the impact of Pim-2 inhibition on bone disease in MM remains unknown. We demonstrated here that Pim-2 expression was also upregulated in bone marrow stromal cells and MC3T3-E1 preosteoblastic cells in the presence of cytokines known as the inhibitors of osteoblastogenesis in MM, including interleukin-3 (IL-3), IL-7, tumor necrosis factor-, transforming growth factor- (TGF-) and activin A, as well as MM cell conditioned media. The enforced expression of Pim-2 abrogated in vitro osteoblastogenesis by BMP-2, which suggested Pim-2 as a negative regulator for osteoblastogenesis. Treatment with Pim-2 short-interference RNA as well as the Pim inhibitor SMI-16a successfully restored osteoblastogenesis suppressed by all the above inhibitory factors and MM cells. The SMI-16a treatment potentiated BMP-2-mediated anabolic signaling while suppressing TGF- signaling. Furthermore, treatment with the newly synthesized thiazolidine-2,4-dione congener, 12a-OH, as well as its prototypic SMI-16a effectively prevented bone destruction while suppressing MM tumor growth in MM animal models. Thus, Pim-2 may have a pivotal role in tumor progression and bone loss in MM, and Pim-2 inhibition may become an important therapeutic strategy to target the MM cell-bone marrow interaction.Leukemia advance online publication, 30 May 2014; doi:10.1038/leu.2014.147. (出版サイトへのリンク) ● Publication site (DOI): 10.1038/leu.2014.147 (文献検索サイトへのリンク) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 24787487 ● Search Scopus @ Elsevier (PMID): 24787487 ● Search Scopus @ Elsevier (DOI): 10.1038/leu.2014.147 (DOI: 10.1038/leu.2014.147, PubMed: 24787487)
35.	Silvia Naomi Mitsui Akagi, Akihiro Yasue, Kiyoshi Masuda, Keiichiro Watanabe, Shinya Horiuchi, Issei Imoto and Eiji Tanaka : Novel PAX9 Mutations Cause Non-syndromic Tooth Agenesis., Journal of Dental Research, Vol.93, No.3, 245-249, 2014. (要約) PAX9 is a transcription factor expressed in the tooth mesenchyme during tooth morphogenesis. In Pax9-null mice, tooth development is arrested at the bud stage. In humans, heterozygous mutations in PAX9 have been associated with non-syndromic tooth agenesis, predominantly in the molars. Here, we report 2 novel mutations in the paired domain of PAX9, a three-nucleotide deletion (73-75 delATC) and a missense mutation (C146T), in two unrelated Japanese patients with non-syndromic tooth agenesis. The individual with the 73-75del ATC mutation was missing all maxillary molars and mandibular second and third molars. The individual with the C146T mutation was missing the mandibular central incisors, maxillary second premolars, and first molars, along with all second and third molars. Both mutations affected amino acids that are highly conserved among different species and are critical for DNA binding. When both mutants were transfected to COS7 cells, nuclear localization of PAX9 proteins was not affected. However, reduced expression of the mutant proteins and almost no transcriptional activity of the target BMP4 gene were observed, suggesting haploinsufficiency of PAX9 as the cause of non-syndromic tooth agenesis. (徳島大学機関リポジトリ) ● Metadata: 109722 (出版サイトへのリンク) ● Publication site (DOI): 10.1177/0022034513519801 (文献検索サイトへのリンク) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 24436340 ● Summary page in Scopus @ Elsevier: 2-s2.0-84894493206 (徳島大学機関リポジトリ: 109722, DOI: 10.1177/0022034513519801, PubMed: 24436340, Elsevier: Scopus)
36.	前田有一, 泰江章博, 大浦徳永律子律子, ミツイアカギシルビアナオミ, 中村竜也, 渡邉佳一郎, 高橋巧, 田中栄二 : Hypodontiaを伴う二卵性双生児の下顎後退症例, 中·四国矯正歯科学会雑誌, Vol.25, No.1, 43-50, 2013年.
37.	Shingen Nakamura, Hirokazu Miki, Shinsuke Kido, Ayako Nakano, Masahiro Hiasa, Asuka Oda, Hiroe Amou, Keiichiro Watanabe, Takeshi Harada, Shiroh Fujii, Kyoko Takeuchi, Kumiko Kagawa, Shuji Ozaki, Toshio Matsumoto and Masahiro Abe : Activating transcription factor 4, an ER stress mediator, is required for, but exce ssive ER stress suppresses osteoblastogenesis by bortezomib., International Journal of Hematology, Vol.98, No.1, 66-73, 2013. (要約) Endoplasmic reticulum (ER) stress is induced in matrix-producing osteoblasts and plays an essential role in osteoblastogenesis. Although the bone anabolic activity of proteasome inhibitors has been demonstrated, the roles of ER stress induced by proteasome inhibition in osteoblastogenesis remain largely unknown. Here we show that bortezomib translationally increases protein levels of activating transcription factor 4 (ATF4), a downstream mediator of ER stress, in bone marrow stromal cells and MC3T3-E1 preosteoblastic cells. The suppression of ATF4 expression by siRNA abrogated osteocalcin expression and mineralized nodule formation by MC3T3-E1 cells induced by bortezomib, indicating a critical role for ATF4 in bortezomib-mediated osteoblastogenesis. However, bortezomib at 20 nM or higher abolished the mineralized nodule formation along with reductions in the expression of osteoblastogenesis mediators β-catenin and Osterix. Furthermore, at 50 nM, bortezomib induced the expression of C/EBP homologous protein (CHOP), suggesting activation of the ATF4-CHOP pro-apoptotic pathway. These results suggest that a low dose of bortezomib induces osteogenic activity, but that, in contrast, excessive ER stress caused by bortezomib at higher doses hampers osteoblastogenesis. Therefore, dosing schedules for proteasome inhibitors warrant further study to maximize anabolic actions without compromising anti-MM activity in patients with multiple myeloma (MM). (キーワード) 3T3 Cells / Activating Transcription Factor 4 / Animals / Antineoplastic Agents / Biological Markers / Bone Marrow Cells / Boronic Acids / Calcification, Physiologic / Cells, Cultured / Endoplasmic Reticulum Stress / Gene Expression Regulation / Gene Silencing / Humans / Mice / Multiple Myeloma / Neoplasm Proteins / Osteoblasts / Osteocalcin / Osteogenesis / Proteasome Inhibitors / Pyrazines / RNA, Small Interfering / Stromal Cells (徳島大学機関リポジトリ) ● Metadata: 105938 (出版サイトへのリンク) ● Publication site (DOI): 10.1007/s12185-013-1367-z (文献検索サイトへのリンク) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 23708974 ● Summary page in Scopus @ Elsevier: 2-s2.0-84880304849 (徳島大学機関リポジトリ: 105938, DOI: 10.1007/s12185-013-1367-z, PubMed: 23708974, Elsevier: Scopus)
38.	Keiichiro Watanabe, Shingo Kuroda, Takumi Takahashi, Takeshi Kijima, Katsuyuki Torikai, Keiji Moriyama and Eiji Tanaka : Segmental distraction osteogenesis with modified LeFort II osteotomy for a patient with craniosynostosis, American Journal of Orthodontics and Dentofacial Orthopedics (AJO-DO), Vol.142, No.5, 698-709, 2012. (要約) In this article, we report successful orthodontic treatment combined with segmental distraction osteogenesis after a modified LeFort II osteotomy in a patient with craniosynostosis. An 8-year-old boy diagnosed with craniosynostosis had a dished-in face, an anterior crossbite, and a skeletal Class III jaw relationship because of midfacial hypoplasia. At the age of 13 years 6 months, the maxillary second and mandibular first premolars were extracted, and leveling and alignment of both arches was started with preadjusted edgewise appliances. At age 14 years 11 months, the patient had a modified LeFort II osteotomy, and the maxillary segment was advanced 7 mm and fixed to the zygomatic bone. At the same time, segmental distraction osteogenesis was started with a rigid external distraction system, and the nasal segment was advanced for 20 days at a rate of 1.0 mm per day. The total active treatment period was 40 months. As a result of the modified segmental distraction osteogenesis, significant improvement of his severe midfacial hypoplasia was achieved without excessive advancement of the maxillary dentition. Both the facial profile and the occlusion were stable after 1 year of retention. However, the nasal segment relapsed 1.4 mm during the 1.5 years after the segmental distraction osteogenesis. Evaluation of the stability and retention suggests that some overcorrection in midfacial advancement is recommended. (出版サイトへのリンク) ● Publication site (DOI): 10.1016/j.ajodo.2012.07.007 (文献検索サイトへのリンク) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 23116511 ● Search Scopus @ Elsevier (PMID): 23116511 ● Search Scopus @ Elsevier (DOI): 10.1016/j.ajodo.2012.07.007 (DOI: 10.1016/j.ajodo.2012.07.007, PubMed: 23116511)
39.	Yuko Tomita, Shingo Kuroda, Tomoko Kataura, Teppei Watanabe, Keiichiro Watanabe, Shinji Fujihara and Eiji Tanaka : Severity of alveolar cleft before palatoplasty affects vertical maxillofacial growth in 6-year-old patients with complete unilateral cleft lip and palate., American Journal of Orthodontics and Dentofacial Orthopedics (AJO-DO), Vol.141, No.4 Suppl, S102-9, 2012. (要約) In this study, we investigated the association between the severity of alveolar clefts in infants and the succeeding maxillofacial growth in patients affected by complete unilateral cleft lip and palate. The subjects were 35 nonsyndromic patients affected by unilateral cleft lip and palate (n = 27) or bilateral cleft lip and palate (n = 8). Plaster models and lateral cephalograms taken at 6 years of age were analyzed and compared with the Japanese norms. In the unilateral cleft lip and palate patients, the relationship between the width of the alveolar cleft before palatoplasty and the skeletal characteristics was also explored. Significant deficiencies of the posterior maxilla and steep palatal planes were noted in both the unilateral and bilateral cleft lip and palate patients. However, they were not clearly observed in the unilateral cleft lip and palate patients born with a small alveolar cleft and were correlated with the severity of alveolar cleft in infancy. Neither cleft type nor the severity of the alveolar cleft was implicated in the maxillary arch form in childhood, but the growth of the alveolar height on the cleft side was less in the unilateral cleft lip and palate patients born with a large alveolar cleft. The severity of the alveolar cleft before palatoplasty affects the succeeding vertical maxillofacial growth in patients affected by unilateral cleft lip and palate; this suggests the necessity of a different diagnosis and treatment in unilateral cleft lip and palate patients according to the severity of the alveolar cleft in infancy. (キーワード) Alveolar Process / 分散分析 (analysis of variance) / Case-Control Studies / Cephalometry / 子ども (children) / Child, Preschool / Cleft Lip / Cleft Palate / Dental Arch / Dental Models / Female / Humans / Imaging, Three-Dimensional / Male / Maxilla / Maxillofacial Development / Models, Anatomic / Palate, Hard / Reference Values / Severity of Illness Index / Statistics, Nonparametric / Vertical Dimension (出版サイトへのリンク) ● Publication site (DOI): 10.1016/j.ajodo.2011.09.010 (文献検索サイトへのリンク) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 22449590 ● Summary page in Scopus @ Elsevier: 2-s2.0-84859083500 (DOI: 10.1016/j.ajodo.2011.09.010, PubMed: 22449590, Elsevier: Scopus)
40.	Hirokazu Miki, Shingen Nakamura, Shuji Ozaki, A Oda, H Amou, Akishige Ikegame, Keiichiro Watanabe, Masahiro Hiasa, Q Cui, T Harada, Shiroh Fujii, A Nakano, Kumiko Kagawa, Kyoko Takeuchi, Ken-ichiro Yata, A Sakai, Masahiro Abe and Toshio Matsumoto : KRN5500, a spicamycin derivative, exerts anti-myeloma effects through impairing both myeloma cells and osteoclasts., British Journal of Haematology, Vol.155, No.3, 328-339, 2011. (要約) The spicamycin analogue KRN5500 alters glycoprotein processing and induces damage in the endoplasmic reticulum (ER)-Golgi apparatus in cancer cells. In the present study, we explored the cytotoxic effects of KRN5500 on multiple myeloma (MM) cells and the bone marrow microenvironment with special reference to ER stress. Cell proliferation assay showed that KRN5500 induced G1 arrest and apoptosis in MM cells in a time- and dose-dependent manner. KRN5500 enhanced ER stress independently of caspase activation in MM cells. This cell death was observed even in the presence of bone marrow stroma cells or osteoclasts. Notably, KRN5500 induced cell death also in osteoclasts. In vivo effects of KRN5500 were evaluated using two xenograft models established in severe combined immunodeficient (SCID) mice by either subcutaneous injection of RPMI 8226 cells or intra-bone injection of INA-6 cells to subcutaneously implanted rabbit bones (SCID-rab model). KRN5500 significantly inhibited tumour growth in both animal models, and decreased the number of osteoclasts, which resulted in prevention of bone destruction in the SCID-rab model. These results suggest that KRN5500 exerts anti-MM effects through impairing both MM cells and osteoclasts. Therefore, this unique mechanism of KRN5500 might be a useful therapeutic option in patients with MM. (キーワード) Animals / Apoptosis / Bone Marrow Cells / Caspases / Cell Line, Tumor / Cell Proliferation / Dose-Response Relationship, Drug / Female / G1 Phase / Humans / Mice / Mice, SCID / Multiple Myeloma / Osteoclasts / Purine Nucleosides / Rabbits / Random Allocation / Stromal Cells / Tumor Microenvironment / Xenograft Model Antitumor Assays (出版サイトへのリンク) ● Publication site (DOI): 10.1111/j.1365-2141.2011.08844.x (文献検索サイトへのリンク) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 21902681 ● Search Scopus @ Elsevier (PMID): 21902681 ● Search Scopus @ Elsevier (DOI): 10.1111/j.1365-2141.2011.08844.x (DOI: 10.1111/j.1365-2141.2011.08844.x, PubMed: 21902681)
41.	Shingo Kuroda, Keiichiro Watanabe, Kyoko Ishimoto, Hideki Nakanishi, Keiji Moriyama and Eiji Tanaka : Long-term stability of LeFort III distraction osteogenesis with a rigid external distraction device in a patient with Crouzon syndrome., American Journal of Orthodontics and Dentofacial Orthopedics (AJO-DO), Vol.140, No.4, 550-561, 2011. (要約) A 6-year-old boy, diagnosed with Crouzon syndrome, had moderate exorbitism, a concave profile, an anterior crossbite of -4.0 mm, and a skeletal Class III jaw-base relationship caused by midfacial hypoplasia. At age 8 years 9 months, a LeFort III osteotomy was performed, and distraction osteogenesis was immediately started with the rigid external distractor system. The midface was advanced approximately 10.0 mm for 6 days, including overcorrection. After the distraction, a reverse headgear was used for 6 years to prevent relapse and to accelerate expected growth. At age 16 years 5 months, after extraction of the maxillary first premolars and mandibular third molars, 0.022-in preadjusted edgewise brackets were placed to treat the edge-to-edge incisor relationship and minor crowding. After 13 months of treatment, the facial profile was significantly improved, and an acceptable occlusion was achieved. During the 9-year observation period after the distraction, acceptable facial growth occurred, and no relapse of the maxillary advancement was observed. However, syndrome-specific growth and methodologically induced relapse should be considered when planning a LeFort III distraction in children for the treatment of Crouzon syndrome. (出版サイトへのリンク) ● Publication site (DOI): 10.1016/j.ajodo.2009.12.038 (文献検索サイトへのリンク) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 21967944 ● Search Scopus @ Elsevier (PMID): 21967944 ● Search Scopus @ Elsevier (DOI): 10.1016/j.ajodo.2009.12.038 (DOI: 10.1016/j.ajodo.2009.12.038, PubMed: 21967944)
42.	高原一菜, 川合暢彦, 中村彩花, 松本一真, 天知良太, 渡邉佳一郎, 川上恵実, 大浦徳永律子律子, 石本恭子, 藤原慎視, 黒田晋吾, 田中栄二 : 徳島大学病院矯正歯科における患者の動向調査, 中·四国矯正歯科学会雑誌, Vol.23, No.1, 77-82, 2011年.
43.	Qu Cui, Hironobu Shibata, Asuka Oda, Hiroe Amou, Ayako Nakano, Kenichiro Yata, Masahiro Hiasa, Keiichiro Watanabe, Shingen Nakamura, Hirokazu Miki, Takeshi Harada, Shiroh Fujii, Kumiko Kagawa, Kyoko Takeuchi, Shuji Ozaki, Toshio Matsumoto and Masahiro Abe : Targeting myeloma-osteoclast interaction with V9V2 T cells., International Journal of Hematology, Vol.94, No.1, 63-70, 2011. (要約) Multiple myeloma (MM) cells stimulate osteoclastogenesis, and osteoclasts (OCs) in turn enhance MM growth and drug resistance, resulting in a vicious cycle. V9V2 T cells exert potent anti-tumor effects, making T cell-based immunotherapies using these cells attractive candidates for currently incurable malignancies, such as MM. However, the impact of such treatments on the MM-OC interaction is largely unknown. We demonstrate here that V9V2 T cells expanded by zoledronic acid and IL-2 exerted potent cytotoxic effects on both MM cells and OCs, even in coculture settings, but showed no such effect on bone marrow stromal cells. V9V2 T cells marginally affected colony formation from normal hematopoietic progenitors, and furthermore migrated toward osteopontin and MIP-1, factors produced by the MM-OC interaction. These results suggest that V9V2 T cells expanded by zoledronic acid and IL-2 are able to migrate to MM bone lesions and preferentially target OCs as well as MM cells, thereby inhibiting both tumor expansion and bone destruction. (出版サイトへのリンク) ● Publication site (DOI): 10.1007/s12185-011-0885-9 (文献検索サイトへのリンク) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 21698356 ● Search Scopus @ Elsevier (PMID): 21698356 ● Search Scopus @ Elsevier (DOI): 10.1007/s12185-011-0885-9 (DOI: 10.1007/s12185-011-0885-9, PubMed: 21698356)
44.	石本恭子, 黒田晋吾, 高橋巧, 渡邉佳一郎, 田中栄二 : ミニスクリュー固定を用いて上顎歯列の遠心移動を行ったアングルⅡ級2類過蓋咬合症例, 中·四国矯正歯科学会雑誌, Vol.21, No.1, 31-39, 2009年.

学術論文(紀要・その他):

1.	Hirofumi Tenshin, Keiichiro Watanabe, Emiko Nakaue, Khurel-Ochir Tsendsuren, Masahiro Hiasa, Shinya Horiuchi and Eiji Tanaka : Identification of key determinant for predicting feasible mandibular molars distalization, Journal of Dental Sciences, 2022. (出版サイトへのリンク) ● Publication site (DOI): 10.1016/j.jds.2022.05.009 (文献検索サイトへのリンク) ● Summary page in Scopus @ Elsevier: 2-s2.0-85132231189 (DOI: 10.1016/j.jds.2022.05.009, Elsevier: Scopus)

総説・解説:

1.	保坂啓一, 渡邉佳一郎, 田中栄二, 中島正俊, 岩﨑智憲 : 【小児のCR(コンポジットレジン)充填アップデート】接着システムのアップデート, 小児歯科臨床, Vol.28, No.12, 15-26, 2023年12月.
2.	保坂啓一, 渡邉佳一郎, 鴨居浩平 : デジタル技術を融合した次世代CR修復 : クオリティの高い修復を効率化するDigitally-guided Composite Injection Technique(12・完)"フル"デジタルガイドCR修復へ : 疑問に答え,現在の到達点から未来を見据える, 日本歯科評論, Vol.82, No.12, 10-13, 2022年12月. (文献検索サイトへのリンク) ● CiNii @ 国立情報学研究所 (CRID): 1520013021075705088 (CiNii: 1520013021075705088)
3.	鴨居浩平, 長谷川勇一, 本山靖治, 石原洋樹, 渡邉佳一郎, 細川育子, 保坂啓一 : デジタル技術を融合した次世代CR修復②:クオリティの高い修復を効率化するDigitally-guided Composite Injection Technique(2)デジタルワークフローを活用したコンポジットインジェクションテクニック(後編), 日本歯科評論, Vol.82, No.2, 10-13, 2022年2月. (文献検索サイトへのリンク) ● CiNii @ 国立情報学研究所 (CRID): 1521417756223847680 (CiNii: 1521417756223847680)

国際会議:

1.	Atsushi Takeya, Keiichiro Watanabe, Taisei Shimomura and Akihiro Haga : Development of an accurate and rapid auto-segmentation method for alveolar bone and teeth using virtual cone-beam computed tomography and artificial intelligence technology, International Conference on Radiological Physics and Technology (ICRPT), Vol.43, No.Sup1, 153-154, Yokohama, Apr. 2023.
2.	J Liu, Keiichiro Watanabe, CC Ko, BS Lee and DG Kim : Effects of Estrogen Deficiency on Jaw and Limb Bones in a Rat Model., ORS2021 annual meeting, Feb. 2021.
3.	Keiichiro Watanabe, CM Han, YH Jeong, AR Altman, J Liu, X Guo, A Ni, M Bahador, T Ebrahimian, N Kim, J Kim, T Deguchi, MJ Shim, BS Lee, XS Liu and DG Kim : Effects of Intermittent Parathyroid Hormone Following Alendronate Treatment on Jawbone of Ovariectomized Rat., ORS2021 annual meeting, Feb. 2021.
4.	Keiichiro Watanabe, B Mitchell, Y Hirai, D-G Kim, T Deguchi and Eiji Tanaka : Mechanical characteristic of a novel thread shape of miniscrew., 9th IOC, Yokohama, Oct. 2020.
5.	J Ferraro, J Falter, S Lee, Keiichiro Watanabe, DG Kim and T Deguchi : The Use of CBCT Derived Printed Models in Orthodontic Diagnosis., IADR 98th general session, Washington, D.C., Mar. 2020.
6.	A Tsatalis, B Mitchell, Keiichiro Watanabe, T Deguchi and DG Kim : Evaluation of the Necessity of CBCT During Placement of TADs., IADR 98th general session, Washington, D.C., Mar. 2020.
7.	Y Huh, Keiichiro Watanabe and DG Kim : Bone Mineral Density Distribution in Mandibular Incisors Region., IADR 98th general session, Washington, D.C., Mar. 2020.
8.	Z Skabelund, Keiichiro Watanabe, S Lee, T Deguchi and DG Kim : Sexual Dimorphism of Temporomandibular Joint Condyle Density Distribution., IADR 98th general session, Washington, D.C., Mar. 2020.
9.	J Liu, Keiichiro Watanabe, ES Moon, Z Skabelund, SH Kim, SR Kim, D Lee, F Zheng, T Deguchi and DG Kim : Sex dependent differences of oral bone mineral density., IADR 98th general session, Washington, D.C., Mar. 2020.
10.	J Lamb, Keiichiro Watanabe, S Lee and DG Kim : Tissue Mineral Density Distribution in Human Mandibular Premolar Region., IADR 98th general session, Washington, D.C., Mar. 2020.
11.	SH Kim, Keiichiro Watanabe, SR Kim, Y Choi, T Deguchi and DG Kim : Functional Demands Change Bone Mineral Density at Different Tooth Locations., IADR 98th general session, Washington, D.C., Mar. 2020.
12.	Keiichiro Watanabe, S Lewis, A Ni, T Deguchi, B Lee and DG Kim : Masticatory Effects On Regional Variation of Estrogen Deficient Rat Jaw Bone Density., Orthopaedic Research Society (ORS) 2020 Annual Meeting, Phoenix, Feb. 2020.
13.	C Kiracofe, Keiichiro Watanabe, H Lee, J Liu, F Zheng and DG Kim : Mastication diminishes effects of estrogen deficiceny on alveolar bone., IADR 97th general session, Vancouver, Jun. 2019.
14.	T Ebrahimian, Keiichiro Watanabe, N Kim, AY Kim, F Zheng, J Liu and DG Kim : Effects of osteoporosis therapeutic agents on oral trabecular bone., IADR 97th general session, Vancouver, Jun. 2019.
15.	J Liu, Keiichiro Watanabe, ES Moon, Z Skabelund, SR Kim, D Lee, F Zheng, T Deguchi and DG Kim : Effect of Aging on Oral Bone Mineral Density Distribution., IADR 97th general session, Vancouver, Jun. 2019.
16.	Z Skabelund, Keiichiro Watanabe, S Lee, T Deguchi and DG Kim : Sex Dependent Differences of Mandibular Condyle Density Distribution., IADR 97th general session, Vancouver, Jun. 2019.
17.	E Sexton, P Kim, Keiichiro Watanabe, T Deguchi and DG Kim : Relationships Between Male and Female Facial Morphological Measurements by CBCT., IADR 97th general session, Vancouver, Jun. 2019.
18.	S Lewis, Keiichiro Watanabe, K Bodnyk, F Zheng and DG Kim : Effects of Low Intensity Vibration on Oral Bone., IADR 97th general session, Vancouver, Jun. 2019.
19.	H Zhang, DG Kim, B Foster, M Chavez, T Kolli, M Tan, H Fong, E Chu, Y Li, X Ren and Keiichiro Watanabe : Dentoalveolar Defects in the Hyp Mouse Model of X-linked Hypophosphatemia., IADR 97th general session, Vancouver, Jun. 2019.
20.	J Ferraro, J Falter, S Lee, Keiichiro Watanabe, DG Kim and T Deguchi : Accuracy of 3-dimentional Printed Models from Intra-oral Scanner and CBCT., IADR 97th general session, Vancouver, Jun. 2019.
21.	SR Kim, Keiichiro Watanabe, SH Kim, A Yousef, T Deguchi and DG Kim : Alveolar Bone Quality Changes Depending on Masticatory Functional Demands., IADR 97th general session, Vancouver, Jun. 2019.
22.	Keiichiro Watanabe, CM Han, A Tsatalis, D Lee, F Zheng, HM Kyung, T Deguchi and DG Kim : Type-dependent Mechanical Stability of Orthodontic Miniscrew Implants., IADR 97th general session, Vancouver, Jun. 2019.
23.	Hirofumi Tenshin, Jumpei Teramachi, Ryota Amachi, Masahiro Hiasa, Keiichiro Watanabe, Toshio Matsumoto, Masahiro Abe and Eiji Tanaka : Apoptosis inducer TRAIL stimulates osteoclast differentiation and survival via TAK1 activation., 1st International Conference of Biophysical Technology in Dentistry (+10th International Scientific Meeting in Dentistry),, Makassar, Indonesia., Apr. 2018.
24.	Hirofumi Tenshin, Jumpei Teramachi, Ryota Amachi, Masahiro Hiasa, Keiichiro Watanabe, Toshio Matsumoto, Masahiro Abe and Eiji Tanaka : Apoptosis inducer TRAIL stimulates osteoclast differentiation and survival via TAK1 activation., The 4th ASEAN plus Tokushima Joint International Conference, Bali, Indonesia, Dec. 2017.
25.	Hirofumi Tenshin, Jumpei Teramachi, A Oda, Ryota Amachi, Masahiro Hiasa, A Baterdene, Keiichiro Watanabe, Shingen Nakamura, Hirokazu Miki, Itsuro Endo, Itsuro Endo, Eiji Tanaka, Toshio Matsumoto and Masahiro Abe : Osteoclasts utilize TRAIL for their NF-B activation, but TAK1 inhibition resumes TRAIL-induced apoptosis in osteoclasts., Australian and New Zealand Bone and Mineral Society 2017, Brisbane, Australia., Jun. 2017.
26.	Ryota Amachi, Masahiro Hiasa, Oda Asuka, Bat-Erdene Ariunzaya, Jumpei Teramachi, Hirofumi Tenshin, Keiichiro Watanabe, Shingen Nakamura, Hirokazu Miki, Kumiko Kagawa, Shiroh Fujii, Toshio Matsumoto, Eiji Tanaka and Masahiro Abe : Osteoblast Creates a Non-permissive Niche for Myeloma Cells, 95th General Session & Exhibition of the IADR program book, San Francisco, Mar. 2017.
27.	Hirofumi Tenshin, Jumpei Teramachi, Ryota Amachi, Masahiro Hiasa, Keiichiro Watanabe, Toshio Matsumoto, Masahiro Abe and Eiji Tanaka : TRAIL Stimulates Osteoclast Differentiation and Survival via TAK1 Activation., 95th General Session & Exhibition of the IADR program book, San Francisco, Mar. 2017.
28.	Hirofumi Tenshin, Jumpei Teramachi, A Oda, Ryota Amachi, Bingzi Dong, Masahiro Hiasa, Keiichiro Watanabe, Ryota Amachi, S Nakamura, H Miki, Itsuro Endo, Eiji Tanaka, Toshio Matsumoto and Masahiro Abe : Osteoclasts utilize an apoptosis-inducer TRAIL as a stimulator for osteoclastogenesis Critical roles of the TAK-1-Pim-2 signaling induced by RANK ligand and TRAIL., ANZBMS 2016 Annual Meeting, Gold Coast, Aug. 2016.
29.	Jumpei Teramachi, Masahiro Hiasa, Asuka Oda, Hirofumi Tenshin, Ryota Amachi, Takeshi Harada, Derek Hanson, Keiichiro Watanabe, Shiroh Fujii, Kumiko Kagawa, Shingen Nakamura, Hirokazu Miki, Itsuro Endo, Shuji Ozaki, Toshio Matsumoto and Masahiro Abe : Pim inhibition suppresses osteoclastogenesis and tumor growth in myeloma, 57th ASH Annual Meeting and Exposition, Orlando, Dec. 2015.
30.	Hirofumi Tenshin, Jumpei Teramachi, A Oda, Ryota Amachi, Masahiro Hiasa, Keiichiro Watanabe, S Nakamura, H Miki, I Endo, Eiji Tanaka, Toshio Matsumoto and Masahiro Abe : TRAIL is not a proapoptotic but rather anti-apoptotic mediator for osteoclasts to stimulate their differentiation and survival, ASBMR 2015 Annual Meeting, Seattle, Oct. 2015.
31.	Ryota Amachi, Masahiro Hiasa, Jumpei Teramachi, Asuka Oda, Hirofumi Tenshin, Keiichiro Watanabe, Shingen Nakamura, Hirokazu Miki, Kumiko Kagawa, Shiroh Fujii, Itsuro Endo, Eiji Tanaka, Toshio Matsumoto and Masahiro Abe : Up-regulation of the pH sensor TRPV1 in myeloma cells and their adaption to an acidic microenvironment, ASBMR 2015 Annual Meeting, Seattle, Oct. 2015.
32.	Jumpei Teramachi, Masahiro Hiasa, Asuka Oda, Hirofumi Tenshin, Ryota Amachi, Takeshi Harada, Keiichiro Watanabe, Shiroh Fujii, Kumiko Kagawa, Shingen Nakamura, Hirokazu Miki, Itsuro Endo, Tatsuji Haneji, Toshio Matsumoto and Masahiro Abe : Pivotal role of TAK-1 in tumor growth and bone destruction in myeloma: Therapeutic impact of TAK-1 inhibition, American Society for Bone and Mineral Research 2015 Annual Meeting, Oct. 2015.
33.	Hirokazu Miki, Shingen Nakamura, Hirofumi Tenshin, Ryota Amachi, Keiichiro Watanabe, Jumpei Teramachi, Shiroh Fujii, Kumiko Kagawa and Masahiro Abe : Effective impairment of myeloma progenitors by hyperthermia: augmentation with bortezomib and Pim inhibition in combination, Clinical Lymphoma, Myeloma & Leukemia, Vol.15, No.S3, e217-e218, Sep. 2015. (出版サイトへのリンク) ● Publication site (DOI): 10.1016/j.clml.2015.07.470 (文献検索サイトへのリンク) ● Search Scopus @ Elsevier (DOI): 10.1016/j.clml.2015.07.470 (DOI: 10.1016/j.clml.2015.07.470)
34.	Shingen Nakamura, Hirokazu Miki, Hirofumi Tenshin, Ryota Amachi, Keiichiro Watanabe, Jumpei Teramachi, Shiroh Fujii, Kumiko Kagawa and Masahiro Abe : Alteration of Pim-2 expression by clinically available anti-myeloma agents: combinatory anti-myeloma effects with Pim inhibition, Clinical Lymphoma, Myeloma & Leukemia, Vol.15, No.S3, e243, Sep. 2015. (出版サイトへのリンク) ● Publication site (DOI): 10.1016/j.clml.2015.07.517 (文献検索サイトへのリンク) ● Search Scopus @ Elsevier (DOI): 10.1016/j.clml.2015.07.517 (DOI: 10.1016/j.clml.2015.07.517)
35.	Silvia Naomi Mitsui Akagi, Akihiro Yasue, K Matsuda, Keiichiro Watanabe, Shinya Horiuchi, Issei Imoto and Eiji Tanaka : Sequence analysis and in vitro study of novel mutations identified in patients with tooth agenesis, The 3rd ASEAN Plus and Tokushima Joint International Conference, Makassar, Indonesia., Dec. 2014.
36.	Jumpei Teramachi, Masahiro Hiasa, 小田明日香, Ryota Amachi, Takeshi Harada, Shingen Nakamura, Kumiko Kagawa, Hirokazu Miki, Shiroh Fujii, Keiichiro Watanabe, Itsuro Endo, Toshio Matsumoto and Masahiro Abe : Critical role of Pim-2 in NF-B-mediated suppression of osteoblastogenesis and stimulation of osteoclastogenesis: Therapeutic impact of Pim inhibition on myeloma bone disease., 2014 ASBMR Annual Meeting, Houston, Sep. 2014.
37.	Ryota Amachi, Masahiro Abe, Masahiro Hiasa, Keiichiro Watanabe, S Fujii, T Harada, H Miki, S Nakamura, I Endo, Eiji Tanaka and Toshio Matsumoto : Acidic conditions epigenetically repress the TRAIL receptor DR4 in myeloma cells to confer their resistance to TRAIL, ASBMR 2013 Annual Meeting,, Baltimore, Oct. 2013.
38.	Keiichiro Watanabe, Masahiro Abe, H Mori, Ryota Amachi, Masahiro Hiasa, T Harada, S Fujii, S Nakamura, H Miki, K Kagawa, I Endo, Eiji Tanaka and Toshio Matsumoto : Potent induction of bone formation in myeloma bone lesions by the cathepsin K inhibitor KK1-300-01 in combination with the proteasome inhibitor bortezomib, ASBMR 2013 Annual Meeting,, Baltimore, Oct. 2013.
39.	Keiichiro Watanabe, Masahiro Abe, Ryota Amachi, Masahiro Hiasa, T Harada, Shiroh Fujii, Shingen Nakamura, Hirokazu Miki, Kumiko Kagawa, H Mori, Itsuro Endo, Eiji Tanaka and Toshio Matsumoto : Induction of bone formation in myeloma osteolytic lesions by cathepsinK inhibition, Kyoto, Apr. 2013.
40.	Ryota Amachi, Keiichiro Watanabe, Shiroh Fujii, T Harada, Hirokazu Miki, Shingen Nakamura, A Oda, Masahiro Hiasa, Eiji Tanaka, Toshio Matsumoto and Masahiro Abe : An acidic milieu suppersses histone acetylation in myeloma cells to down-regulate the TRAIL receptor DR4 expression., Kyoto, Apr. 2013.
41.	Ryota Amachi, Masahiro Abe, Ryota Amachi, Keiichiro Watanabe, S Fujii, T Harada, H Miki, S Nakamura, A Oda, Masahiro Hiasa, Eiji Tanaka and Toshio Matsumoto : An acidic milieu suppresses DR4 editing to cause myeloma resistance to TRAIL, ASEAN plus and Tokushima Joint International Conference, Yogjakarta, Indonesia, Dec. 2012.
42.	Masahiro Hiasa, Keiichiro Watanabe, Shingen Nakamura, Harada Takeshi, Itsuro Endo, Toshio Matsumoto and Masahiro Abe : Prevention of tumor growth and bone destruction in myeloma by Pim kinase inhibition, 12th Int'l Meeting on Cancer Induced Bone Disease, Lyon, Nov. 2012.
43.	Masahiro Hiasa, Ryota Amachi, Keiichiro Watanabe, Harada Takeshi, Fujii Shirou, Shingen Nakamura, Hirokazu Miki, Kumiko Kagawa, Itsuro Endo, Toshio Matsumoto and Masahiro Abe : Pim-2 suppresses BMP-2 signaling as a common inhibitory mediator of osteoblastogenesis in myeloma, ASBMR 2012 Anuual Meeting, Minneapolis, Oct. 2012.
44.	Keiichiro Watanabe, Masahiro Abe, Ryota Amachi, Masahiro Hiasa, T Harada, S Fujii, S Nakamura, H Miki, K Kagawa, H Mori, I Endo, Eiji Tanaka and Toshio Matsumoto : Restoration of bone formation in myeloma osteolytic lesions by the cathepsin K inhibitor KK1-300-01, 34th ASBMR meeting, Minneapolis, MN, USA., Oct. 2012.
45.	Keiichiro Watanabe, Masahiro Abe, Hiroyo Mori, Ryota Amachi, Masahiro Hiasa, T Harada, S Fujii, S Nakamura, H Miki, K Kagawa, I Endo, Eiji Tanaka and Toshio Matsumoto : The cathepsin K inhibitor KK1-300-01 prevents bone destruction and resumes bone formation in myeloma osteolytic lesions, Australian & New Zealand Bone & Mineral Society 22th Annual Scientific Meeting with 1st Asia-Pacific Bone and Mineral Research meeting, Perth, Australia., Sep. 2012.
46.	Keiichiro Watanabe, Masahiro Abe, M Kawatani, Masahiro Hiasa, A Kawano, T Jinno, T Harada, Shiroh Fujii, Shingen Nakamura, Hirokazu Miki, Kumiko Kagawa, Kyoko Takeuchi, Shuji Ozaki, Eiji Tanaka, H Osada and Toshio Matsumoto : Aggravation of myeloma growth and drug resistance by an acidic created in myeloma-osteoclast interaction., ASBMR 2011 Annual Meeting, San Diego, Sep. 2011.
47.	Masahiro Hiasa, nakano ayako, Keiichiro Watanabe, C Qu, T Harada, Shiroh Fujii, Hirokazu Miki, Shingen Nakamura, Kumiko Kagawa, Kyoko Takeuchi, Eiji Tanaka, Kenzo Asaoka, Shuji Ozaki, Toshio Matsumoto and Masahiro Abe : Prevention of tumor growth and bone destruction in myeloma by Pim kinase inhibition., ASBMR 2011 Annual Meeting, San Diego, Sep. 2011.
48.	Masahiro Hiasa, nakano ayako, Keiichiro Watanabe, C Qu, T Harada, Shiroh Fujii, Hirokazu Miki, Shingen Nakamura, Kumiko Kagawa, Kyoko Takeuchi, Eiji Tanaka, Kenzo Asaoka, Shuji Ozaki, Toshio Matsumoto and Masahiro Abe : Dual effects of Pim inhibition on myeloma: induction of bone formation and tumor suppression., IOF-ANZBMS 2011 Annual Meeting, Gold Coast, Sep. 2011.
49.	Keiichiro Watanabe, Masahiro Abe, Cui Qu, Kawatani Makoto, Masahiro Hiasa, Nakano Ayako, Jinno Tadashi, Harada Takeshi, Shiroh Fujii, Shingen Nakamura, Miki Hirokazu, Kumiko Kagawa, Kyoko Takeuchi, Shuji Ozaki, Eiji Tanaka, Osada Hiroyuki and Toshio Matsumoto : An Acidic Mileu Created In Myeloma-Osteoclast Interaction Enhances Tumor Growth, but Triggers Anti-Myeloma Activity of Reveromycin A, a Novel Anti-Resorptive Agent, 52th American Society of Hematology, Orlando, Dec. 2010.
50.	Cui Qu, Masahiro Abe, Miki Hirokazu, Shingen Nakamura, Keiichiro Watanabe, Akishige Ikegame, Masahiro Hiasa, Nakano Ayako, Harada Takeshi, Shiroh Fujii, Kumiko Kagawa, Kyoko Takeuchi, Shuji Ozaki and Toshio Matsumoto : Lenalidomide In Combination with Zoledronic Acid Restores the Activation and Anti-Myeloma Effects of γδT Cells Attenuated by the Bone Marrow Microenvironment, 52th American Society of Hematology, Orlando, Dec. 2010.
51.	Keiichiro Watanabe, Masahiro Abe, Cui Qu, Kawatani Makoto, Masahiro Hiasa, Nakano Ayako, Jinno Tadashi, Harada Takeshi, Shiroh Fujii, Shingen Nakamura, Miki Hirokazu, Kumiko Kagawa, Kyoko Takeuchi, Shuji Ozaki, Eiji Tanaka, Osada Hiroyuki and Toshio Matsumoto : A Novel Anti-resorptive Agent, Reveromycin A, Ameliorates Bone Destruction and Tumor Growth in Myeloma, ASBMR 2010 Annual Meeting, Toronto, Oct. 2010.
52.	Masahiro Hiasa, Masahiro Abe, nakano ayako, oda aska, amo hiroe, Keiichiro Watanabe, Shingen Nakamura, miki hirokazu, Kyoko Takeuchi, Kumiko Kagawa, Shuji Ozaki, Eiji Tanaka, Kenzo Asaoka and Toshio Matsumoto : Bone Marrow Stromal Cells Suppress TACE-mediated M-CSFR and RANK Shedding to Facilitate Osteoclastogenesis and Suppress DC Differentiation from Monocytes., ASBMR 2010 Annual Meeting, Toronto, Oct. 2010.
53.	Masahiro Abe, Masahiro Hiasa, Nakano A, Shingen Nakamura, Miki H, Qu C, Keiichiro Watanabe, Harada T, Kumiko Kagawa, Kyoko Takeuchi, Shuji Ozaki and Toshio Matsumoto : TIMP-3 up-regulation facilitates osteoclastogenesis and suppresses DC differentiation from monocytes in the bone marrow microenvironment in myeloma, 10th International Conference Cancer-induced Bone Disease, Sep. 2010. (キーワード) Sheffield (United Kingdom)
54.	Keiichiro Watanabe, Masahiro Abe, Cui Qu, Kawatani Makoto, Masahiro Hiasa, Nakano Ayako, Jinno Tadashi, Harada Takeshi, Shiroh Fujii, Shingen Nakamura, Miki Hirokazu, Kumiko Kagawa, Kyoko Takeuchi, Shuji Ozaki, Eiji Tanaka, Osada Hiroyuki and Toshio Matsumoto : The novel anti-resorptive agent reveromycin A ameliorates bone destruction and tumor growth in myeloma, 10th International Conference Cancer-induced Bone Disease, Sheffield (United Kingdom), Sep. 2010.

国内講演発表:

1.	内海雄太, 川野沙織, 松木優承, 渡邉佳一郎, 大毛健一郎, 伊田百美香, 米倉和秀, 田中栄二, 保坂啓一 : 上顎側切歯1歯欠損に対して，デジタルワークフローを活用したインジェクションテクニックにより，2層のダイレクトボンディングブリッジを行った審美修復症例, 日本歯科審美学会, 2023年12月.
2.	内海雄太, 松木優承, 渡邉佳一郎, 川野沙織, 井内智貴, 大毛健一郎, 伊田百美香, 米倉和秀, 保坂啓一 : 矯正歯科治療後，デジタルワークフローを活用したコンポジットレジンインジェクションテクニックにより犬歯誘導を獲得した1症例, 日本歯科保存学会 2023年秋季学術大会, 2023年11月.
3.	峯田一秀, 吉永薫, 渡邉佳一郎, 山崎裕行, 美馬俊介, 安倍吉郎, 田中栄二, 橋本一郎 : ファーラー法による口蓋形成の術直前後と3か月後のにおける硬口蓋の形態評価, 第41回日本頭蓋顎顔面外科学会学術集会, 2023年11月.
4.	花輪茂己, 日浅雅博, 岩浅亮彦, 渡邉佳一郎, 天眞寛文, 木内奈央, 堀内信也, 田中栄二 : 上顎左側第二小臼歯先天性欠如を伴う片側性唇顎口蓋裂患者に対して下顎左側第二小臼歯を移植した一症例, 中·四国矯正歯科学会雑誌, Vol.35, No.1, 67-75, 2023年8月. (要約) 口唇裂・口蓋裂患者では永久歯が先天性欠如する割合が高く,とくに複数歯が先天性欠如する症例の場合,マルチブラケット装置を用いた治療の際に咬合の確立に苦慮することは少なくない.今回,上顎左側側切歯および第二小臼歯の先天性欠如を伴う左側唇顎口蓋裂患者に対して,便宜抜去した下顎左側第二小臼歯を上顎左側第二小臼歯欠如部に移植し全顎的な矯正治療を行うことで良好な治療結果が得られたので報告する.初診時年齢0歳20日の女児で,左側唇顎口蓋裂を主訴に当院形成外科から紹介され来院した.12歳時,下顎歯列におけるarch length discrepancyの改善のために抜去した下顎左側第二小臼歯を上顎左側第二小臼歯欠如部へ移植した.12歳10ヵ月時,移植歯の歯根形成と根尖孔閉鎖が認められ,顎骨の成長がほぼ終了したため,二期治療としてマルチブラケット装置を用いて咬合の確立を図った.動的治療期間は5年0ヵ月で,1歯対2歯の緊密な咬合関係が獲得された.現在,保定後2年3ヵ月経過して安定した咬合を維持している.本症例では,便宜抜去した歯を移植することで,補綴処置を回避し,天然歯による緊密な咬合を獲得することができた.移植後2年経過した時点で歯根吸収は認めず,安定した経過をたどっている.しかしながら今後も長期的な観察が必要と考えられる.口唇裂・口蓋裂患者の歯の先天性欠如部位に対する治療法の一つとして歯の移植が有用であることが示唆された.(著者抄録) (キーワード) パノラマX線撮影法 X線診断自家移植下顎骨歯根吸収(合併症,X線診断,外科的療法) 上顎疾患(合併症,外科的療法,診断) 小臼歯(移植) 頭部計測法歯(移植) 無歯症(合併症,外科的療法,診断) 歯科矯正維持装置歯科矯正用ブラケット *唇顎口蓋裂(合併症,外科的療法,診断) ヒト新生児女歯学
5.	田中茉里子, 堀内信也, 日浅雅博, 渡邉佳一郎, 岩浅亮彦, 田中栄二 : 術後に顎関節に疼痛を訴えた下顎骨左方偏位を伴う骨格性上顎前突症例, 中·四国矯正歯科学会雑誌, Vol.35, No.1, 77-86, 2023年8月. (要約) 顎偏位を伴う骨格性上顎前突患者に対し,咬合平面の傾斜と下顎骨左方偏位および後退の改善を目的として上下顎同時移動術を施行し,術後に顎関節の変調をきたした症例を経験したので報告する.初診時25歳9ヵ月の女性で,顔面の非対称と上顎前突を主訴に来院した.顔面正中に対して上顎歯列正中は一致し,下顎歯列正中は6.0mm左方に偏位していた.咬合平面は2.0°左上がりに傾斜し,左側下顎枝は右側に比べ短かった.Overjetは8.5mm,overbiteは2.5mmであった.咬合平面の傾斜,下顎の左方偏位と後退を改善するため,上顎Le Fort I型骨切り術および下顎枝矢状骨切り術を施行した.顎骨の移動量については上顎右側臼歯部で5.5mmの圧下および左側臼歯部で1.5mmの圧下を計画した.下顎は右側臼歯部で4.0mmの後方移動および左側臼歯部で5.0mmの前方移動を計画した.術後,左側顎関節の疼痛を訴えたため,II級ゴムと上下顎同時移動術に用いたセカンドスプリントから移行した下顎前方整位型スプリントを使用したところ,関節部の疼痛は軽減した.段階的にII級ゴムとスプリントの装着時間を短くした結果,下顎の後退が観察され,overjetが増加傾向を示したため,歯科矯正用アンカースクリューを固定源として使用した上顎歯列の遠心移動を行った.術後2年8ヵ月経過時に,良好な咬合が獲得され下顎位も安定したため保定へと移行した.現在保定後5年4ヵ月経過して,緊密な咬合状態が保たれている.下顎の前方移動を伴う外科的矯正治療は,顎関節に不調をきたすことも多く,術後長期にわたる経過観察と,治療変化に対応し得る余地を残した治療計画を勘案する必要性が示唆された.(著者抄録) (キーワード) パノラマX線撮影法 X線診断下顎骨顎関節疾患(病因,診断,治療) 顎の奇形(合併症,外科的療法,診断) 顎前突症(合併症,外科的療法,診断) 歯科矯正ワイヤー MRI 術後痛(診断,治療) 頭部計測法 *関節痛(病因,診断,治療) オクルーザルスプリント LeFort骨切り術歯科矯正用ブラケット下顎枝矢状分割術歯科矯正用固定源埋込みエッジワイズ法矯正的遠心移動ヘッドギアヒト成人(19∼44) 女歯学
6.	西田真衣, 堀内信也, 清水宗, 田中茉里子, 和田涼平, 谷本幸多朗, 渡邉佳一郎, 田中栄二 : 徳島大学病院矯正歯科における成長ホルモン投与矯正患者に関する実態調査, 中·四国矯正歯科学会雑誌, Vol.35, No.1, 115, 2023年8月. (キーワード) 成長ホルモン(治療的利用) 外来患者歯科矯正治療 *病院歯科診療部門実態調査ヒト男女歯学
7.	近藤英司, 坂本幸, 島田亜紀, 吉永薫, 北村尚正, 山崎裕行 (名), 峯田一秀, 渡邉佳一郎, 日浅雅博, 堀内信也, 岩﨑智憲, 橋本一郎, 田中栄二 : 徳島大学病院における口蓋裂児の滲出性中耳炎と鼓膜チューブ留置術の検討, 第47回日本口蓋裂学会, 2023年5月.
8.	坂本幸, 近藤英司, 島田亜紀, 吉永薫, 北村尚正, 山崎裕行, 峯田一秀, 渡邉佳一郎, 日浅雅博, 堀内信也, 岩﨑智憲, 橋本一郎, 田中栄二 : 徳島大学病院における口蓋裂児の滲出性中耳炎と鼓膜チューブ留置術の検討, 第47回日本口蓋裂学会, 2023年5月.
9.	坂本幸, 近藤英司, 島田亜紀, 吉永薫, 北村尚正, 山崎裕行, 峯田一秀, 渡邉佳一郎, 日浅雅博, 堀内信也, 岩﨑智憲, 橋本一郎, 田中栄二 : 徳島大学病院における口蓋裂児の新生児聴覚スクリーニング結果と滲出性中耳炎罹患率, 日本口蓋裂学会雑誌, Vol.48, No.2, 153, 2023年4月. (キーワード) 口蓋裂(合併症) 新生児スクリーニング中耳炎-滲出性(診断,合併症) 発生率大学病院聴覚検査ヒト乳児(1∼23ヶ月) 幼児(2∼5) 男女歯学
10.	近藤英司, 坂本幸, 島田亜紀, 吉永薫, 北村尚正, 山崎裕行, 峯田一秀, 渡邉佳一郎, 日浅雅博, 堀内信也, 岩﨑智憲, 橋本一郎, 田中栄二 : 徳島大学病院における口蓋裂児の滲出性中耳炎と鼓膜チューブ留置術の検討, 日本口蓋裂学会雑誌, Vol.48, No.2, 154, 2023年4月. (キーワード) 口蓋裂(合併症) 中耳炎-滲出性(外科的療法,合併症) *中耳換気大学病院結果再現性ヒト乳児(1∼23ヶ月) 幼児(2∼5) 小児(6∼12) 青年期(13∼18) 男女歯学
11.	和田涼平, 渡邉佳一郎, 吉永薫, 金秀河, 花輪茂己, 田中茉里子, 坂本幸, 島田亜紀, 近藤英司, 北村尚正, 山崎裕行, 峯田一秀, 日浅雅博, 堀内信也, 岩﨑智憲, 橋本一郎, 田中栄二 : 徳島大学病院における過去10年間の口唇裂・口蓋裂患者に関する臨床統計調査, 日本口蓋裂学会雑誌, Vol.48, No.2, 200, 2023年4月. (キーワード) 口蓋裂口唇裂統計大学病院ヒト男女歯学
12.	峯田一秀, 金秀河, 渡邉佳一郎, 山崎裕行, 山下雄太郎, 安倍吉郎, 田中栄二, 橋本一郎 : 徳島大学病院口唇口蓋裂センター設立前後での患者動向の検討, 第40回日本頭蓋顎顔面外科学会学術集会, 2022年11月.
13.	渡邉佳一郎, 天眞寛文, 中上絵美子, 塩屋園玲子, 田中栄二 : 上顎歯列の全体的な圧下を行い骨格的な改善を図った，ガミースマイルを伴う成人骨格性上顎前突症例, 第81回日本矯正歯科学会学術大会, 2022年10月.
14.	岩浅亮彦, 比嘉佳基, 中上絵美子, 吉永薫, 清水宗, 松木佑太, 谷本幸多朗, 渡邉佳一郎, 日浅雅博, 堀内信也, 田中栄二 : 特発性下顎頭吸収を呈する矯正患者の下顎頭の形態学的特徴, 第81回日本矯正歯科学会学術大会, 2022年10月.
15.	中上絵美子, 渡邉佳一郎, 天眞寛文, 吉永薫, 松木佑太, 日浅雅博, 堀内信也, 田中栄二 : 実現可能な下顎臼歯遠心移動の予測に必要な決定因子の特定, 中·四国矯正歯科学会雑誌, 2022年7月.
16.	坂巻拓馬, 渡邉佳一郎, 岩浅亮彦, 金秀河, 田中栄二 : 歯科矯正用アンカースクリューの初期安定性に対する皮質骨厚の影響, 中·四国矯正歯科学会雑誌, 2022年7月.
17.	田中茉里子, 堀内信也, 日浅雅博, 渡邉佳一郎, 岩浅亮彦, 髙丸菜都美, 永井宏和, 宮本洋二, 田中栄二 : 術後に顎関節に変調をきたした顎偏位を伴う骨格性上顎前突症例, 第32回日本顎変形症学会総会・学術大会, Vol.32, No.2, 171, 2022年6月.
18.	花輪茂己, 日浅雅博, 岩浅亮彦, 渡邉佳一郎, 天眞寛文, 木内奈央, 堀内信也, 田中栄二 : 上顎左側第二小臼歯先天欠損を伴う片側性唇顎口蓋裂患者に対して下顎左側第二小臼歯を移植した一症例, 日本口蓋裂学会雑誌, Vol.47, No.2, 146, 2022年5月.
19.	金秀河, 渡邉佳一郎, 吉永薫, 天眞寛文, 中上絵美子, 比嘉佳基, 坂本幸, 近藤英司, 島田亜紀, 峯田一秀, 石田創士, 宮嵜彩, 北村尚正, 日浅雅博, 堀内信也, 岩﨑智憲, 橋本一郎, 田中栄二 : 徳島大学病院における口唇口蓋裂センター設立前後での患者動向の変化金秀河(徳島大学大学院口腔科学教育部口腔顎顔面矯正学分野), 渡邉佳一郎, 吉永薫, 天眞寛文, 中上絵美子, 比嘉佳基, 坂本幸, 近藤英司, 島田亜紀, 峯田一秀, 石田創士, 宮嵜彩, 北村尚正, 日浅雅博, 堀内信也, 岩崎智憲, 橋本一郎, 田中栄二日本口蓋裂学会雑誌(0386-5185)47巻2号 Page135(2022.04), 日本口蓋裂学会雑誌, Vol.47, No.2, 135, 2022年5月.
20.	渡邉佳一郎, 天眞寛文, 吉永薫, 中上絵美子, 坂本幸, 近藤英司, 島田亜紀, 峯田一秀, 石田創士, 日浅雅博, 堀内信也, 岩﨑智憲, 橋本一郎, 田中栄二 : Pre-epiglottic baton plateによる保存的治療で重度気道閉塞の改善がみられたPierre Robin Sequenceの1例, 日本口蓋裂学会雑誌, Vol.47, No.2, 116, 2022年4月. (キーワード) Pierre Robin症候群(合併症) 気道閉塞(合併症,診断,予後) 呼吸障害(病因,予後) *保存的療法哺乳障害(病因,予後) ヒト新生児男歯学
21.	小山智史, 郷司彩, 森達夫, 中川竜二, 渡邉佳一郎, 鴨居浩平, 福田潤弥 : Pre-epiglottic baton plateを用いて上気道狭窄に対応したPierre-Robin Sequenceの1例, 第73回中国四国小児科学会, 2021年11月.
22.	渡邉佳一郎, 荒井大志, 篠原丈裕, 岩浅亮彦, 田中栄二 : 歯科矯正用アンカースクリューを用いて咬合の構築を行った全顎的な鋏状咬合と過蓋咬合を伴う重度歯槽性上顎前突症例, 日本矯正歯科学会雑誌, 2021年11月.
23.	渡邉佳一郎, Bobby Mitchell, 平井雄三, Do-gyoon Kim, 出口徹, 田中栄二 : 新しいネジ山形状を有する歯科矯正用アンカースクリューの機械的安定性に関する研究, 日本矯正歯科学会雑誌, 2021年11月.
24.	天眞寛文, 渡邉佳一郎, 中上絵美子, 田中栄二 : 歯科矯正用アンカースクリューを用いた積極的な臼歯圧下により治療を行なった成人骨格性開咬症例, 第80回日本矯正歯科学会学術大会, 2021年10月.
25.	岩浅亮彦, 渡邉佳一郎, 伊藤彩実, 塩屋園玲子, 坂巻拓馬, 比嘉佳基, 小笠原直子, 堀内信也, 田中栄二 : Hemifacial microsomiaに対して矯正歯科治療単独で緊密な咬合を獲得した3症例, 中·四国矯正歯科学会雑誌, Vol.33, No.1, 86, 2021年7月.
26.	平井雄三, 渡邉佳一郎, 中上絵美子, 吉村宗之, 天眞寛文, 日浅雅博, 田中栄二 : 歯科矯正用アンカースクリューおよび周囲骨の応力分布に及ぼす植立深さの影響:有限要素法による解析, 中·四国矯正歯科学会雑誌, Vol.33, No.1, 80, 2021年7月.
27.	渡邉佳一郎, 天眞寛文, 峯田一秀, 石田創士, 吉永薫, 中上絵美子, 比嘉佳基, 宮嵜彩, 北村尚正, 坂本幸, 近藤英司, 島田亜紀, 日浅雅博, 堀内信也, 橋本一郎, 田中栄二 : 当院における口腔内スキャナーを活用した哺乳床早期装着のための取り組み, 日本口蓋裂学会雑誌, Vol.46, No.2, 123, 2021年4月. (キーワード) 口蓋裂口唇裂歯科用機器母乳栄養ヒト乳児(1∼23ヶ月) 歯学
28.	吉永薫, 塩屋園玲子, 伊藤彩実, 松木祐太, 谷本幸多朗, 渡邉佳一郎, 田中栄二 : ソトス症候群に起因する交叉咬合を伴う骨格性下顎前突, 第63回中・四国矯正歯科学会大会, 2020年7月.
29.	中上絵美子, 渡邉佳一郎, 森浩喜, 天眞寛文, 堀内信也, 田中栄二 : カモフラージュ治療が行われた片側性完全唇顎口蓋裂患者の動的治療終了時の顎顔面形態の特徴, 第30回日本顎変形症学会総会・学術大会, Vol.30, No.2, 164, 2020年6月.
30.	中上絵美子, 渡邉佳一郎, 森浩喜, 天眞寛文, 堀内信也, 田中栄二 : カモフラージュ治療が行われた片側性完全唇顎口蓋裂患者の動的治療終了時の顎顔面形態の特徴, 第44回日本口蓋裂学会総会・学術集会, 2020年6月.
31.	渡邉佳一郎, 田中栄二, 出口徹 : 口腔内スキャナーおよびCBCT画像を組み合わせた3次元歯科模型の開発, 第78回日本矯正歯科学会学術大会: 日本矯正歯科学会大会プログラム・抄録集 78回 Page206.(2019), 206, 2019年11月.
32.	T Deguchi, J Ferraro, J Falter, S Lee, Keiichiro Watanabe and DG Kim : Accuracy of 3-dimentional printed models from intra-oral scanner and CBCT., 第78回日本矯正歯科学会学術大会, Nov. 2019.
33.	森仁志, 森浩喜, 塩屋園玲子, 渡邉佳一郎, 堀内信也, 菅野貴浩, 田中栄二 : 閉塞性睡眠時無呼吸症候群を伴うPierre Robin Sequenceに対し下顎骨前方移動術を行った1例, 第62回中・四国矯正歯科学会大会, Vol.31, No.1, 2019年7月.
34.	清水宗, 堀内信也, 天眞寛文, 岩浅亮彦, 渡邉佳一郎, 日浅雅博, 岩本勉, 田中栄二 : 徳島大学病院矯正歯科における口唇裂・口蓋裂患者の合併先天異常に関する実態調査．, 日本口蓋裂学会雑誌, 2019年5月.
35.	森仁志, 森浩喜, 塩屋園玲子, 渡邉佳一郎, 堀内信也, 田中栄二 : 上顎中切歯の翼状捻転を伴う叢生症例, 第61回中・四国矯正歯科学会大会, Vol.30, No.1, 77-78, 2018年7月.
36.	岩浅亮彦, 小西晴奈, 藤本果南, 小笠原直子, 渡邉佳一郎, 日浅雅博, 堀内信也, 田中栄二 : 徳島大学病院矯正歯科患者における永久歯埋伏に関する臨床統計学的調査, 第76回日本矯正歯科学会学術大会, 2017年10月.
37.	天眞寛文, 寺町順平, 小田明日香, 天知良太, 日浅雅博, 渡邉佳一郎, Ariunzaya Baterdene, 岩佐昌美, 藤井志朗, 賀川久美子, 中村信元, 三木浩和, 遠藤逸朗, 田中栄二, 松本俊夫, 安倍正博 : TRAILは破骨細胞を活性化させるが，TAK1阻害により骨髄腫細胞とともに破骨細胞にもTRAILのアポトーシス誘導活性が惹起できる, 第35回日本骨代謝学会学術集会, 2017年7月.
38.	森仁志, 森浩喜, 塩屋園玲子, 渡邉佳一郎, 堀内信也, 田中栄二 : ペンデュラムアプライアンスを使用して上顎第一大臼歯を遠心移動した3症例, 第60回中・四国矯正歯科学会大会, 2017年7月.
39.	藤本果南, 小西晴奈, 岩浅亮彦, 市原亜起, 白井愛実, 渡邉佳一郎, 日浅雅博, 森博世, 堀内信也, 田中栄二 : 歯科矯正患者における埋伏永久歯に関する実態調査, 第60回中・四国矯正歯科学会大会, 2017年7月.
40.	荒井大志, 渡邉佳一郎, Hutami Islamy Rahma, 天眞寛文, 篠原丈裕, 木内奈央, 田中栄二 : 矯正歯科患者における近年の永久前歯歯冠幅径の変化, 第60回中・四国矯正歯科学会大会学術口演, 2017年7月.
41.	天眞寛文, 寺町順平, 小田明日香, 天知良太, 日浅雅博, Baterdene Ariunzaya, 渡邉佳一郎, 中村信元, 三木浩和, 遠藤逸朗, 田中栄二, 松本俊夫, 安倍正博 : TAK1阻害はTRAILの抗骨髄腫作用を増強するともに骨吸収促進活性を抑制活性に変換する．, 第42回日本骨髄腫学会, 2017年5月.
42.	天知良太, 中村信元, 日浅雅博, 小田明日香, バットエルデネアリウンザヤ, 寺町順平, 天眞寛文, 渡邉佳一郎, 三木浩和, 賀川久美子, 藤井志朗, 田中栄二, 松本俊夫, 安倍正博 : 骨形成誘導による骨髄腫細胞のエネルギー代謝の抑制, 第42回日本骨髄腫学会学術集会, 2017年5月.
43.	小西晴奈, 藤本果南, 岩浅亮彦, 渡邉佳一郎, 堀内信也, 田中栄二 : 不正咬合患者における埋伏歯についての臨床統計学的調査, 四国歯学会第50回例会, 2017年3月.
44.	天眞寛文, 寺町順平, 小田明日香, 天知良太, 日浅雅博, 渡邉佳一郎, 中村信元, 三木浩和, 遠藤逸朗, 田中栄二, 松本俊夫, 安倍正博 : 30. 天真寛文, 寺町順平, 小田明日香, 天知良太, , ,破骨細胞系細胞はアポトーシス誘引因子TRAILを生存促進・破骨細胞形成誘導因子として利用する:TAK1-Pim-2経路の役割, 第19回日本癌と骨病変研究会, 2016年11月.
45.	天眞寛文, 渡邉佳一郎, 白井愛実, 七條なつ子, 田中栄二 : 新たな下顎臼歯の遠心移動量および移動様式の予測指標の開発-第2報-, 日本矯正歯科学会大会プログラム・抄録集. 第75回大会, 2016年11月.
46.	渡邉佳一郎, 天眞寛文, 白井愛実, 七條なつ子, 田中栄二 : 新たな下顎臼歯の遠心移動量および移動様式の予測指標の開発-第1報-, 日本矯正歯科学会大会プログラム・抄録集. 第75回大会, 2016年11月.
47.	森仁志, 森浩喜, 篠原丈裕, 天知良太, 塩屋園玲子, 渡邉佳一郎, 堀内信也, 菅野貴浩, 田中栄二 : 比較的大きな顎裂を有する口唇口蓋裂患者に対する骨トランスポート骨延長法の応用, 日本矯正歯科学会大会プログラム・抄録集., 263., 2016年11月.
48.	天眞寛文, 寺町順平, 小田明日香, 天知良太, 日浅雅博, 渡邉佳一郎, 中村信元, 三木浩和, 遠藤逸朗, 田中栄二, 松本俊夫, 安倍正博 : TAK1 inhibition subverts TRAIL-mediated osteoclastogenesis., 第77回日本血液学会学術集会,, 2016年10月.
49.	天知良太, 日浅雅博, 寺町順平, 小田明日香, 天眞寛文, 渡邉佳一郎, 中村信元, 三木浩和, 賀川久美子, 藤井志朗, 遠藤逸郎, 田中栄二, 松本俊夫, 安倍正博 : Mechanism of the TRPV1 up-regulatation in myeloma cells and adaptation to an acidic microenvironment., 第77回日本血液学会学術集会,, 2016年10月.
50.	渡邉佳一郎, 寺町順平, 天知良太, 小田明日香, 天眞寛文, 岩浅正美, 日浅雅博, 中村信元, 遠藤逸郎, 川谷誠, 長田裕之, 田中栄二, 松本俊夫, 安倍正博 : Amelotin gene expression is temporarily being upregulated at the initiation of apoptosis induced by TGFb1 in mouse gingival epithelial cells, 第77回日本血液学会学術集会,, 2016年10月.
51.	黒田優子, 堀内信也, 渡邉佳一郎, 泰江章博, 田中栄二 : 口唇裂口蓋裂児の裂型は幼児期における上顎歯槽部の垂直的な成長に影響を及ぼす, 中·四国矯正歯科学会雑誌, Vol.28, No.(1), 127, 2016年8月.
52.	渡邉佳一郎, 寺町順平, 天知良太, 小田明日香, 天眞寛文, 日浅雅博, 中村信元, 三木浩和, 遠藤逸朗, 川谷誠, 長田裕之, 田中栄二, 松本俊夫, 安倍正博 : リベロマイシンAによる酸性環境での骨髄腫細胞の治療抵抗性の克服, 日本骨代謝学会学術集会プログラム抄録集 (1349-0761)34回 Page183(2016.07), 183, 2016年7月.
53.	天眞寛文, 寺町順平, 小田明日香, 天知良太, 日浅雅博, 渡邉佳一郎, 中村信元, 三木浩和, 遠藤逸朗, 田中栄二, 松本俊夫, 安倍正博 : 破骨細胞はTAK1の発現誘導を介しアポトーシスを抑制しTRAILにより成熟活性化される, 日本骨代謝学会学術集会プログラム抄録集 (1349-0761)34回 Page183(2016.07), 183, 2016年7月.
54.	寺町順平, 日浅雅博, 小田明日香, 天眞寛文, 天知良太, 原田武志, 渡邉佳一郎, 中村信元, 三木浩和, 遠藤逸朗, 羽地達次, 松本俊夫, 安倍正博 : 骨髄腫腫瘍進展と骨破壊病変形成におけるTAK1-Pim-2経路の役割, 日本骨代謝学会学術集会プログラム抄録集, 2016年7月.
55.	寺町順平, 日浅雅博, 小田明日香, 原田武志, 天眞寛文, 中村信元, 天知良太, 藤井志朗, 渡邉佳一郎, 賀川久美子, 三木浩和, 遠藤逸朗, 羽地達次, 松本俊夫, 安倍正博 : Pim-2は骨髄腫における破骨細胞形成促進の必須媒介因子である, 第41回日本骨髄腫学会学術集会, 2016年5月.
56.	天眞寛文, 寺町順平, 小田明日香, 天知良太, 日浅雅博, 渡邉佳一郎, 中村信元, 三木浩和, 遠藤逸朗, 田中栄二, 松本俊夫, 安倍正博 : TRAILは破骨細胞に細胞死を誘導せず，破骨細胞分化・生存を促進する., 第41回日本骨髄腫学会, 2016年5月.
57.	MANSJUR KARIMA QURNIA, Shingo Kuroda, Yuichi Maeda, Minami Sato, Silvia Naomi Mitsui Akagi, ODO BAYARSAIKHAN, Keiichiro Watanabe and Eiji Tanaka : Applications of parathyroid hormone and low intensity pulsed ultrasound enhance fracture healing in osteoporotic rats, 第74回日本矯正歯科学会大会プログラム・抄録集, 142, Nov. 2015.
58.	Ryota Amachi, Masahiro Hiasa, Jumpei Teramachi, A Oda, Hirofumi Tenshin, Keiichiro Watanabe, Shingen Nakamura, H Miki, Kumiko Kagawa, Shiroh Fujii, Eiji Tanaka, Toshio Matsumoto and Masahiro Abe : Mechanism of the TRPV1 up-regulatation in myeloma cells and adaptation to an acidic microenvironment, 第77回日本血液学会学術集会, Oct. 2015.
59.	Keiichiro Watanabe, Jumpei Teramachi, H Mori, Y Ochi, Ryota Amachi, A Oda, Masahiro Hiasa, T Harada, Shiroh Fujii, Shingen Nakamura, H Miki, Kumiko Kagawa, Itsuro Endo, Eiji Tanaka, Toshio Matsumoto and Masahiro Abe : Potent induction of bone formation by anti-resorptive cathepsin K inhibitor in myeloma, 第77回日本血液学会学術集会, Oct. 2015.
60.	寺町順平, 日浅雅博, Asuka Oda, 天眞寛文, 天知良太, Takeshi Harada, 渡邉佳一郎, 藤井志朗, 賀川久美子, 中村信元, 三木浩和, 遠藤逸朗, 羽地達次, 松本俊夫, 安倍正博 : Potent suppression of osteoclastogenesis in myeloma by Pim inhibition, 第77回日本血液学会学術集会, 2015年10月.
61.	Jumpei Teramachi, Masahiro Hiasa, Asuka Oda, Hirofumi Tenshin, Ryota Amachi, Takeshi Harada, Keiichiro Watanabe, Shiroh Fujii, Kumiko Kagawa, Shingen Nakamura, Hirokazu Miki, Itsuro Endo, Tatsuji Haneji, Toshio Matsumoto and Masahiro Abe : Tumor reduction and bone restoration in myeloma by TAK-1 inhibition, 第77回日本血液学会学術集会, Oct. 2015.
62.	吉永薫, 渡邉佳一郎, 中村瑠里, 佐藤南, ミツイアカギシルビアナオミ, 天知良太, 岩浅亮彦, 堀内信也, 黒田晋吾, 田中栄二 : 歯科矯正用アンカースクリューの導入による診断内容の変化∼抜歯・非抜歯および抜歯部位の判定に関する検討∼, 第58回中·四国矯正歯科学会大会, 18, 2015年7月.
63.	天眞寛文, 渡邉佳一郎, 七條なつ子, 三野彰子, 森浩喜, KARIMA QURNIA MANSJUR, 泰江章博, 黒田晋吾, 田中栄二 : 歯科矯正用アンカースクリューを用いた下顎臼歯遠心移動量および移動様式の治療前予測に関する検討, 第58回中·四国矯正歯科学会大会, 14, 2015年7月.
64.	天眞寛文, 寺町順平, 小田明日香, 天知良太, 渡邉佳一郎, 中村信元, 三木浩和, 遠藤逸朗, 田中栄二, 松本俊夫, 安倍正博 : TRAILは破骨細胞分化・生存を促進する:TAK-1による生と死の運命制御, 第1回日本骨免疫学会, 137, 2015年7月.
65.	天知良太, 日浅雅博, 寺町順平, 小田明日香, 天眞寛文, 渡邉佳一郎, 中村信元, 賀川久美子, 三木浩和, 藤井志朗, 遠藤逸朗, 田中栄二, 松本俊夫, 安倍正博 : 酸環境での骨髄腫細胞のDR4発現抑制:酸によるエピジェネティックな遺伝子発現制御, 第1回日本骨免疫学会, 108, 2015年7月.
66.	天知良太, 日浅雅博, 寺町順平, 小田明日香, 渡邉佳一郎, 天眞寛文, 中村信元, 三木浩和, 遠藤逸朗, 近藤剛史, 田中栄二, 松本俊夫, 安倍正博 : 酸性環境での骨髄腫細胞のTRPV1の発現亢進と酸環境への適応, 日本骨代謝学会学術集会プログラム抄録集, 165, 2015年7月.
67.	天眞寛文, 寺町順平, 小田明日香, 天知良太, 日浅雅博, 渡邉佳一郎, 中村信元, 三木浩和, 遠藤逸朗, 田中栄二, 松本俊夫, 安倍正博 : アポトーシス誘導因子TRAILによる破骨細胞分化・生存の促進, 日本骨代謝学会学術集会プログラム抄録集, 164, 2015年7月.
68.	高原一菜, 堀内信也, 渡邉佳一郎, 黒田晋吾, 橋本一郎, 田中栄二 : 顎裂部唇側に腸骨海綿骨移植術を施行した両側性唇顎口蓋裂症例, 日本口蓋裂学会雑誌抄録号(39回総会・学術集会), Vol.40, No.2, 161, 2015年5月.
69.	MANSJUR KARIMA QURNIA, Shingo Kuroda, Minami Sato, KHALIUNAA GANZORIG, Yuichi Maeda, Keiichiro Watanabe, Shinya Horiuchi and Eiji Tanaka : Effectiveness of low-intensity pulsed ultrasound for the treatment of tibial fractures in osteoporotic rats, 第73回日本矯正歯科学会大会・第5回日韓ジョイントミーティングプログラム・抄録集, 350, Oct. 2014.
70.	天知良太, 日浅雅博, 渡邉佳一郎, 寺町順平, 小田明日香, 渡邉佳一郎, 中村信元, 遠藤逸朗, 田中栄二, 松本俊夫, 安倍正博 : 酸が惹起する骨髄腫細胞の酸感受と生存シグナルの悪循環, 日本骨代謝学会学術集会プログラム抄録集, 225, 2014年7月.
71.	篠原丈裕, 渡邉佳一郎, 森浩喜, 井澤俊, 堀内信也, 黒田晋吾, 田中栄二 : 顎関節内障を有する骨格性下顎前突症に対する矯正歯科治療の一治験例, 第57回中·四国矯正歯科学会大会, 21, 2014年7月.
72.	篠原丈裕, 渡邉佳一郎, 三野彰子, 米田尚子, 高原一菜, 泰江章博, 堀内信也, 黒田晋吾, 田中栄二 : 口唇裂・口蓋裂患者における歯科矯正治療の実態調査, 第38回日本口蓋裂学会総会・学術集会, 2014年5月.
73.	Keiichiro Watanabe, Masahiro Abe, H Mori, K Udaka, M Iwasa, D Hanson, Ryota Amachi, Masahiro Hiasa, T Harada, Shiroh Fujii, Shingen Nakamura, H Miki, Kumiko Kagawa, Itsuro Endo, Eiji Tanaka and Toshio Matsumoto : Bone restoration and tumor suppression in myeloma by cathepsin K inhibition with Bortezomib, 第75回日本血液学会学術集会, Oct. 2013.
74.	天知良太, 渡邉佳一郎, 日浅雅博, 安倍正博, 松本俊夫, 田中栄二 : 酸性環境が骨髄腫細胞の破骨細胞活性に及ぼす影響, 第72回日本矯正歯科学会大会プログラム・抄録集, 2013年10月.
75.	井上雅秀, 黒田晋吾, 渡邉佳一郎, 七條なつ子, 荒古江圭嗣, 上田寛治, 田中栄二 : 歯科矯正用アンカースクリューの直径，埋入角度および荷重方向の違いが周囲骨組織内応力分布へ及ぼす影響, 第72回日本矯正歯科学会大会プログラム・抄録集, 2013年10月.
76.	渡邉佳一郎, 黒田晋吾, 森浩喜, 田中栄二 : 歯科矯正用アンカースクリューを用いて治療した成長期の骨格性II級前歯部開咬症例, 第72回日本矯正歯科学会大会プログラム・抄録集, 2013年10月.
77.	森浩喜, 渡邉佳一郎, 内田玲子, 井澤俊, 黒田晋吾, 森仁志, 田中栄二 : 圧迫骨短縮術を施術した，エナメル質形成不全を伴う骨格性開咬の一治療例, 第56回中·四国矯正歯科学会大会, 2013年7月.
78.	Ryota Amachi, Keiichiro Watanabe, Shiroh Fujii, T Harada, H Miki, S Nakamura, A Oda, Masahiro Hiasa, Eiji Tanaka, Toshio Matsumoto and Masahiro Abe : An acdic milieu confers the resistance to TRAIL in myeloma cells through the PI3K-Akt-mediated epigenetic down-regulation of the TRAIL receptor DR4, International Bone and Mineral Society 2013, May 2013.
79.	Keiichiro Watanabe, Masahiro Abe, H Mori, Ryota Amachi, Masahiro Hiasa, T Harada, Shiroh Fujii, S Nakamura, H Miki, K Kagawa, I Endo, Eiji Tanaka and Toshio Matsumoto : Induction of cathepsin K induce bone formation in myeloma osteolytic lesions, International Bone and Mineral Society 2013, May 2013.
80.	Ryota Amachi, Keiichiro Watanabe, Shiroh Fujii, T Harada, H Miki, S Nakamura, A Oda, Masahiro Hiasa, Eiji Tanaka, Toshio Matsumoto and Masahiro Abe : An acdic milieu suppresses histone acetylation in myeloma cells to down-regulate the TRAIL receptor DR4 expression, 14th International Myeloma Workshop, Apr. 2013.
81.	Keiichiro Watanabe, Masahiro Abe, Ryota Amachi, Masahiro Hiasa, T Harada, Shiroh Fujii, S Nakamura, H Miki, K Kagawa, I Endo, Eiji Tanaka and Toshio Matsumoto : Induction of bone formation in myeloma osteolytic lesions by cathepsin K inhibition, 14th International Myeloma Workshop, Apr. 2013.
82.	Silvia Naomi Mitsui Akagi, Akihiro Yasue, Keiichiro Watanabe, Shinya Horiuchi and Eiji Tanaka : Candidate gene analysis in patients with tooth agenesis, 第60回国際歯科研究学会日本部会総会・学術大会, Dec. 2012.
83.	阿部直樹, 渡邉佳一郎, 黒田晋吾, 田中栄二 : 顔認証システムを用いた顎矯正手術後の顔貌予測システムの開発, 第30回日本頭蓋顎顔面外科学会学術大会, 2012年11月.
84.	渡邉佳一郎, 黒田晋吾, 中西秀樹, 田中栄二 : 機能的矯正装置による顎整形的治療を行ったHemifacial microsomiaの長期観察例, 第30回日本頭蓋顎顔面外科学会学術大会, 2012年11月.
85.	藤井志朗, 安倍正博, 天知良太, 渡邉佳一郎, 日浅雅博, 竹内恭子, 岩佐昌美, 原田武志, 中村信元, 三木浩和, 賀川久美子, 松本俊夫 : Pim inhibition preferentially induces anti-myeloma activity in an acidic milien, 第74回日本血液学会学術集会, 2012年10月.
86.	Masahiro Hiasa, Masahiro Abe, Kumiko Kagawa, Hirokazu Miki, Shingen Nakamura, Harada Takeshi, Fujii Shirou, Keiichiro Watanabe, Ryota Amachi, Kenzo Asaoka and Toshio Matsumoto : Pim-2 acts as a common downstream mediator to suppress bone formation in myeloma., 第74回に本血液学会, Oct. 2012.
87.	Ryota Amachi, Masahiro Abe, Keiichiro Watanabe, Masahiro Hiasa, Eiji Tanaka and Toshio Matsumoto : An acidic milieu suppresses DR4 editing and induces p22 c-FLIP to cause myeloma resistance to TRAIL, 第74回日本血液学会学術集会, Oct. 2012.
88.	Silvia Naomi Mitsui Akagi, Akihiro Yasue, Keiichiro Watanabe, Teppei Watanabe, Naoko Yoneda, Shinya Horiuchi and Eiji Tanaka : Msx1 gene analysis in non-syndromic tooth agenesis, 第71回日本矯正歯科学会大会プログラム・抄録集, 301, Sep. 2012.
89.	井上雅秀, 黒田晋吾, 渡邉佳一郎, 高原一菜, 森博世, 田中栄二 : ミニスクリューの埋入時トルクが成功率に及ぼす影響, 第71回日本矯正歯科学会大会プログラム・抄録集, 213, 2012年9月.
90.	渡邉佳一郎, 安倍正博, 天知良太, 日浅雅博, 中村信元, 遠藤逸郎, 森裕史, 田中栄二, 松本俊夫 : カテプシンK 阻害剤KK1-300-01 は骨髄腫骨病変部の骨破壊を抑制し骨形成を惹起する, 第30回日本骨代謝学会学術大会, 217, 2012年7月.
91.	天知良太, 安倍正博, 渡邉佳一郎, 中村信元, 日浅雅博, 田中栄二, 松本俊夫 : 酸性環境は骨髄腫細胞にDR4 の発現抑制とcFLIP の活性化を惹起しTRAIL に対する抵抗性を獲得させる, 第30回日本骨代謝学会学術集会, 259, 2012年7月.
92.	森仁志, 渡邉佳一郎, 内田玲子, 堀内信也, 田中栄二 : 口唇裂・口蓋裂患者に対するセミカスタムメイド創内固定型延長器を用いた上顎骨延長後の安定性の検討, 第55回中・四国矯正歯科学会大会, 41, 2012年7月.
93.	前田有一, 泰江章博, 大浦徳永律子律子, 中村竜也, 渡邉佳一郎, 田中栄二 : Hypodontiaを伴う二卵性双生児の上顎前突症例, 第55回中・四国矯正歯科学会大会, 24, 2012年7月.
94.	Keiichiro Watanabe, Masahiro Abe, Q Cui, Masahiro Hiasa, M Kawatani, T Harada, Shiroh Fujii, Shingen Nakamura, Hirokazu Miki, A Nakano, K Kagawa, K Takeuchi, H Osada, Eiji Tanaka and Toshio Matsumoto : Targeting an acidic microenvironment by reveromycin A to overcome drug resistance to myeloma cells and ameliorate bone disease., 第36回日本骨髄腫研究会総会, Nov. 2011.
95.	堀内信也, 黒田晋吾, 日浅雅博, 天知良太, 渡邉佳一郎, 川上恵実, 川合暢彦, 田中栄二 : S-PRGフィラー含有矯正歯科用接着剤の歯質脱灰抑制効果に関する検討, 日本矯正歯科学会大会プログラム・抄録集, 312, 2011年10月. (キーワード) 歯科矯正装置; 歯科矯正治療; 歯牙接着法; 接着剤; フッ素; 歯牙脱灰(予防) / フィラー / ヒト; 歯学
96.	Masahiro Hiasa, A Nakano, Keiichiro Watanabe, C Qu, T Harada, S Fujii, H Miki, S Nakamura, K Kagawa, K Takeuchi, Eiji Tanaka, Kenzo Asaoka, Shuji Ozaki, Toshio Matsumoto and Masahiro Abe : Prevention of tumor growth and bone destruction in myeloma by Pim kinase inhibition, Bone Biology Forum, 19-21st Aug, 2011, Shizuoka., Aug. 2011.
97.	日浅雅博, 安倍正博, 中野綾子, 渡邉佳一郎, 中村信元, 田中栄二, 淺岡憲三, 松本俊夫 : Pimキナーゼの阻害は骨芽細胞分化を促進し，骨髄腫骨病変の形成と腫瘍進展を抑制する, 日本骨代謝学会学術集会プログラム抄録集, 178, 2011年7月.
98.	渡邉佳一郎, 安倍正博, 川谷誠, 日浅雅博, 中村信元, 田中栄二, 長田裕之, 松本俊夫 : リベロマイシンAによる酸性環境がもたらす骨髄腫薬剤耐性の克服と骨病変形成の抑制, 日本骨代謝学会学術集会プログラム抄録集, 208, 2011年7月.
99.	日浅雅博, 安倍正博, 中野綾子, 渡邉佳一郎, 中村信元, 田中栄二, 淺岡憲三, 松本俊夫 : Pimキナーゼの阻害は骨芽細胞分化を促進し，骨髄腫骨病変の形成と腫瘍進展を抑制する, 日本骨代謝学会学術集会プログラム抄録集, 178, 2011年. (キーワード) 癌原遺伝子蛋白質(拮抗物質・阻害物質); 骨芽細胞; 骨疾患(病因,実験的); 骨髄腫(合併症,実験的); 細胞分化; Protein-Serine-Threonine Kinases(拮抗物質・阻害物質) / Mouse Pim2 Protein(拮抗物質・阻害物質) / マウス; 動物
100.	渡邉佳一郎, 安倍正博, 川谷誠, 日浅雅博, 中村信元, 田中栄二, 長田裕之, 松本俊夫 : リベロマイシンAによる酸性環境がもたらす骨髄腫薬剤耐性の克服と骨病変形成の抑制, 日本骨代謝学会学術集会プログラム抄録集, 208, 2011年. (キーワード) Pyrans; Spiro Compounds; 骨疾患; 骨髄腫; 抗腫瘍剤耐性 / Reveromycin A
101.	渡邉佳一郎, 安倍正博, Cui Qu, Kawatani Makoto, 日浅雅博, Nakano Ayako, Jinno Tadashi, Harada Takeshi, 藤井志朗, 中村信元, Miki Hirokazu, 賀川久美子, 竹内恭子, 尾崎修治, 田中栄二, Osada Hiroyuki, 松本俊夫 : Reveromycin A prevents bone destruction and suppresses tumor growth in myeloma, 第72回日本血液学会, 2010年12月.
102.	渡邉佳一郎, 黒田晋吾, 田中栄二 : 変則型Le Fort II型骨切りを用いて仮骨延長を行ったCrouzon症候群の一症例, 第69回日本矯正歯科学会大会, 2010年10月.
103.	賀川久美子, 神野雅, 原田武志, Cui Qu, 渡邉佳一郎, 日浅雅博, 小田明日香, 天羽宏枝, 池亀彰茂, 三木浩和, 藤井志朗, 中野綾子, 竹内恭子, 尾崎修治, 安倍正博, 松本俊夫 : Sensitization of hematopietic malignant cells to TRAIL with bortezomib and a TACE inhibitor, 第72回日本血液学会, 2010年9月.
104.	中村信元, 安倍正博, Cui Qu, 渡邉佳一郎, 池亀彰茂, 日浅雅博, 三木浩和, 中野綾子, 小田明日香, 天羽宏枝, 神野雅, 原田武志, 藤井志朗, 賀川久美子, 竹内恭子, 尾崎修治, 松本俊夫 : Bortezomib-induced osteoblast differentiation is hampered by excessive ER stress, 第72回日本血液学会, 2010年9月.
105.	日浅雅博, 安倍正博, 中野綾子, 小田明日香, 天羽宏枝, 竹内恭子, 賀川久美子, 中村信元, 三木浩和, 矢田健一郎, 渡邉佳一郎, 尾崎修治, 淺岡憲三, 田中栄二, 松本俊夫 : Bone marrow stromal cells supress TACE activity in monocytes to induce osteoclastogenesis, 第72回日本血液学会, 2010年9月.
106.	Cui Qu, Masahiro Abe, Miki Hirokazu, Shingen Nakamura, Keiichiro Watanabe, Akishige Ikegame, Masahiro Hiasa, Nakano Ayako, Jinnno Tadashi, Harada Takeshi, Shiroh Fujii, Kumiko Kagawa, Kyoko Takeuchi, Shuji Ozaki and Toshio Matsumoto : Bone marrow stromal cells attenuate gama delta T, 第72回日本血液学会, Sep. 2010.
107.	日浅雅博, 安倍正博, 中野綾子, 小田明日香, 天羽宏枝, 竹内恭子, 賀川久美子, 中村信元, 三木浩和, 矢田健一郎, 渡邉佳一郎, 尾崎修治, 淺岡憲三, 田中栄二, 松本俊夫 : 骨髄間質細胞は，単球のTACE活性を抑制し樹状細胞分化を抑制し破骨細胞文化を誘導する, 第28回日本骨代謝学会, 2010年7月.
108.	渡邉佳一郎, 安倍正博, Kawatani Makoto, 日浅雅博, 中村信元, 田中栄二, 長田裕之, 松本俊夫 : リベロマイシンAは骨髄腫骨破壊病変の形成と腫瘍進展を抑制する, 第28回日本骨代謝学会, 2010年7月.
109.	中村信元, 安倍正博, Cui Qu, 渡邉佳一郎, 池亀彰茂, 日浅雅博, 三木浩和, 中野綾子, 小田明日香, 天羽宏枝, 神野雅, 原田武志, 藤井志朗, 賀川久美子, 竹内恭子, 尾崎修治, 松本俊夫 : ボルテゾミブによる骨芽細胞分化の促進は過剰な小胞体ストレスによって抑制される, 第28回日本骨代謝学会, 2010年7月.
110.	内田玲子, 泰江章博, 渡邉佳一郎, 松田りえ, 天地良太, 堀内信也, 大西正人, 高道康宏, 田中栄二 : 徳島大学病院矯正歯科における顎変形症患者の臨床統計学的検討, 第53回中・四国矯正歯科学会学術大会, 2010年7月.
111.	木島毅, 鳥飼勝行, 長西裕樹, 錦織なぎ, 大木健作, 渡邉佳一郎, 田中栄二, 森山啓司, 山本真弓, 島崎一夫, 米満郁男, 大村進 : 梨状孔縁骨切・骨延長により中顔面の形態改善を図ったsyndromic craniosynostosisの1例, 第20回日本顎変形症学会総会プログラム・抄録号, Vol.22, No.2, 152, 2010年6月.
112.	渡邉佳一郎, 木内奈央, 中村彩花, 川合暢彦, 黒田晋吾, 田中栄二 : 混合歯列期にLe Fort III型骨延長術を行ったCrouzon症候群男児の長期観察例, 第52回中・四国矯正歯科学会学術大会, 2009年7月.
113.	石本恭子, 藤原慎視, 木内奈央, 中村竜也, 渡邉哲平, 渡邉佳一郎, 近藤優子, 黒田晋吾, 田中栄二 : 石本恭子，藤原慎視，木内奈央，中村竜也，渡邉哲平，渡邉佳一郎，近藤優子，黒田晋吾，田中栄二:片側性口唇裂・口蓋裂児の顎裂の重篤度が顎顔面の成長発育に影響を及ぼす, 第33回日本口蓋裂学会総会, 2009年5月.
114.	渡邉佳一郎, 木内奈央, 近藤優子, 中村竜也, 石本恭子, 渡邉哲平, 藤原慎視, 黒田晋吾, 田中栄二 : 5歳時における片側性及び両側性口唇・口蓋裂児の顎顔面形態の比較, 第33回日本口蓋裂学会総会, 2009年5月.
115.	渡邉哲平, 近藤優子, 藤原慎視, 中村竜也, 渡邉佳一郎, 石本恭子, 木内奈央, 黒田晋吾, 田中栄二 : 片側性口唇・口蓋裂児の顎裂の重篤度と上顎骨歯槽幅径の成長変化の関連性, 第33回日本口蓋裂学会総会, 2009年5月.

その他・研究会:

1.	保坂啓一, 中島正俊, 渡邉佳一郎, 田中栄二, 鴨居浩平 : MI時代のコンポジットレジン修復戦略∼SLDPによる接着耐久性向上と，フルデジタルガイドインデックス活用∼．Dental Magazine．モリタ 184:30-33．2023．3月号, Dental Magazine, 2023年3月.
2.	天知良太, 安倍正博, 渡邉佳一郎, 賀川久美子, 藤井志朗, 原田武志, 三木浩和, 渡邉佳一郎, 小野明日香, 日浅雅博, 田中栄二, 松本俊夫 : 骨髄腫の酸性環境はTRAIL受容体発現をエピジェネティックに抑制し，TRAIL抵抗性をもたらす, 第20回徳島骨代謝研究会, 2013年11月.
3.	渡邉佳一郎, 安倍正博, 松本俊夫 : リベロマイシンAによる酸性環境がもたらす骨髄腫薬剤耐性の克服と骨病変形成の制御, 第15回癌と骨病変研究会, 2012年11月.
4.	Keiichiro Watanabe, Ryota Amachi, Masahiro Hiasa, Shingen Nakamura, Itsuro Endo, Hiroshi Mori, Eiji Tanaka and Toshio Matsumoto : The cathepsinK inhibitor ONO-KK1-300-01 (ONO-KK1) prevents bone destruction and restores bone formation in myeloma bone lesions, Bone Seminar, Aug. 2012.
5.	天知良太, 安倍正博, 渡邉佳一郎, 賀川久美子, 藤井志郎, 原田武志, 三木浩和, 中村信元, 小田明日香, 日浅雅博, 田中栄二, 松本俊夫 : 酸環境は骨髄腫細胞のTRAILに対する抵抗性を増強する, 第3回骨バイオサイエンス研究会, 2012年7月.
6.	日浅雅博, 安倍正博, 中野綾子, 渡邉佳一郎, 竹内恭子, 賀川久美子, 三木浩和, 中村信元, 藤井志朗, 原田武志, 尾崎修治, 田中栄二, 淺岡憲三, 松本俊夫 : Pimキナーゼの阻害による骨髄腫の進展抑制, 癌と骨病変研究会, 2011年11月.
7.	渡邉佳一郎, 安倍正博, 崔衢, 川谷誠, 日浅雅博, 長田裕之, 田中栄二, 松本俊夫 : A novel anti-resorptive agent, reveromycin A, ameliorates bone destruction and tumor growth in myeloma, 第2回骨バイオサイエンス研究会, 2011年7月.
8.	日浅雅博, 安倍正博, 中野綾子, 小田明日香, 天羽宏枝, 竹内恭子, 賀川久美子, 中村信元, 三木浩和, 矢田健一郎, 渡邉佳一郎, 尾崎修治, 淺岡憲三, 田中栄二, 松本俊夫 : 骨髄間質細胞は，単球のTACE活性を抑制し樹状細胞分化を抑制し破骨細胞文化を誘導する, 第17回徳島骨代謝研究会, 2010年11月.
9.	渡邉佳一郎, 安倍正博, 崔衢, 川谷誠, 長田裕之, 田中栄二, 松本俊夫 : リベロマイシンAの骨髄腫骨病変と腫瘍進展抑制作用, 第1回骨バイオサイエンス研究会, 2010年6月.

特許:

1.	渡邉佳一郎, 保坂啓一, 鴨居浩平, 田中栄二 : 歯科治療用インデックス，歯科治療用インデックス固定クリップ及び歯科治療セット, 特願2023-075731 (2023年5月), 特許第2023-075731号.

科学研究費補助金 (KAKEN Grants Database @ NII.ac.jp)

OSA患者のいびきの周波数解析から発生メカニズム解明と新たな口腔内装置開発の試み (研究課題/領域番号: 22K11447 )
癌細胞の低酸素、酸性環境下における薬剤耐性に対する治療薬の開発 (研究課題/領域番号: 15K20536 )
破骨細胞との共存下における癌細胞の生存促進と薬剤耐性の機序の解明およびその克服 (研究課題/領域番号: 24890152 )
研究者番号（20634554）による検索

助教 : 渡邉佳一郎

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助教 : 渡邉 佳一郎

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科学研究費補助金 (KAKEN Grants Database @ NII.ac.jp)

助教 : 渡邉佳一郎