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Tokushima UniversityUniversity HospitalCentral Clinical FacilitiesRegioal Neurosurgery
Tokushima UniversityUniversity HospitalClinical DivisionDepartment of Neurosurgery, Psychiatry and AnesthesiologyNeurosurgery
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Academic Paper (Judged Full Paper):

1. Shotaroh Yoshioka, Takeshi Miyamoto, Junichiro Satomi, Yoshiteru Tada, Kenji Yagi, Kenji Shimada, Koji Naruishi, Eiji Shikata, Izumi Yamaguchi, Tadashi Yamaguchi, Masaaki Korai, Yoshihiro Okayama, Masafumi Harada, Keiko Kitazato, Yasuhisa Kanematsu, Shinji Nagahiro and Yasushi Takagi :
Disequilibrium of Plasma Protease/Anti-Protease Due to Severe Periodontal Disease Contributes to Human Subarachnoid Hemorrhage,
Neurosurgery Open, Vol.1, No.3, 1-9, 2020.
(Tokushima University Institutional Repository: 115292,   DOI: 10.1093/neuopn/okaa007)
2. Nobuaki Yamamoto, Yuki Yamamoto, Izumi Yamaguchi, Manabu Ishihara, Takeshi Miyamoto, Masaaki Korai, Kenji Shimada, Yasuhisa Kanematsu, Yuishin Izumi and Yasushi Takagi :
Cone beam-computed tomography angiography by intravenous contrast injection is reliable to evaluate patients with large vessel occlusion,
Journal of Clinical Neuroscience, Vol.70, 67-71, 2019.
(DOI: 10.1016/j.jocn.2019.08.078,   PubMed: 31445814,   Elsevier: Scopus)
3. Izumi Yamaguchi, Yasuhisa Kanematsu, Kenji Shimada, Masaaki Korai, Takeshi Miyamoto, Eiji Shikata, Tadashi Yamaguchi, Nobuaki Yamamoto, Yuki Yamamoto, Keiko Kitazato, Yoshihiro Okayama and Yasushi Takagi :
Active Cancer and Elevated D-Dimer Are Risk Factors for In-Hospital Ischemic Stroke,
Cerebrovascular Diseases Extra, Vol.9, No.3, 129-138, 2019.
(Tokushima University Institutional Repository: 115057,   DOI: 10.1159/000504163,   PubMed: 31760390,   Elsevier: Scopus)
4. Tadashi Yamaguchi, Takeshi Miyamoto, keiko Kitazato, Eiji Shikata, Izumi Yamaguchi, Masaaki Korai, Kenji Shimada, Kenji Yagi, Yoshiteru Tada, Yoshihito Matsuzaki, Yasuhisa Kanematsu and Yasushi Takagi :
Time-dependent and site-dependent morphological changes in rupture-prone arteries: ovariectomized rat intracranial aneurysm model,
Journal of Neurosurgery, 2019.
(Tokushima University Institutional Repository: 113804,   DOI: 10.3171/2019.6.JNS19777,   PubMed: 31518986)
5. Eiji Shikata, Tetsuya Tamura, Kiyohito Shinno, Yoshihiro Okayama, Naoki Shinohara, Kenji Shimada, Yasuhisa Kanematsu, Keiko T Kitazato, Shinji Nagahiro and Yasushi Takagi :
Importance of Managing the Water-Electrolyte Balance by Delivering the Optimal Minimum Amount of Water and Sodium After Subarachnoid Hemorrhage.,
World Neurosurgery, Vol.129, e352-e360, 2019.
(DOI: 10.1016/j.wneu.2019.05.152,   PubMed: 31132492)
6. Toshiyuki Okazaki, Yasuhisa Kanematsu, Kenji Shimada, Masaaki Korai, Junichiro Satomi, Masaaki Uno, Shinji Nagahiro and Yasushi Takagi :
A Single-center Retrospective Study with 5- and 10-year Follow-up of Carotid Endarterectomy with Patch Graft.,
Neurologia Medico-Chirurgica, Vol.59, No.6, 231-237, 2019.
(DOI: 10.2176/nmc.oa.2018-0309,   PubMed: 31061257)
7. Yamamoto Yuki, Nobuaki Yamamoto, Yasuhisa Kanematsu, Masaaki Korai, Kenji Shimada, Yuishin Izumi and Yasushi Takagi :
The Claw Sign: An angiographic Predictor of Recanalization After Mechanical Thrombectomy for Cerebral Large Vessel Occlusion.,
Journal of Stroke & Cerebrovascular Diseases, Vol.28, No.6, 1555-1560, 2019.
(Tokushima University Institutional Repository: 114639,   DOI: 10.1016/j.jstrokecerebrovasdis.2019.03.007,   PubMed: 30930237)
8. Akemi Hioka, Yoshiteru Tada, Keiko Kitazato, Yasuhisa Kanematsu, Yoshifumi Mizobuchi, Hideo Mure, Kenji Shimada, Toshiyuki Okazaki, Masaaki Korai, Noki Akazawa, Yuki Matsumoto, Yuki Matsumoto, Yasushi Takagi and Shinji Nagahiro :
Activation of mirror neuron system during gait observation in sub-acute stroke patients and healthy persons.,
Journal of Clinical Neuroscience, Vol.60, 79-83, 2019.
(Tokushima University Institutional Repository: 113267,   DOI: 10.1016/j.jocn.2018.09.035,   PubMed: 30318398)
9. Nobuaki Yamamoto, Yuki Yamamoto, Masaaki Korai, Kenji Shimada, Yasuhisa Kanematsu, Yuishin Izumi, Junichiro Satomi, Yasushi Takagi and Ryuji Kaji :
Simultaneous approach to tandem occlusion in acute ischemic stroke patients: Percutaneous Transluminal Angioplasty (PTA) using push wire of stent retriever,
JNET, Vol.13, No.6, 257-261, 2019.
(DOI: 10.5797/jnet.cr.2018-0108,   CiNii: 130007665498)
10. Shinji Nagahiro, Yoshiteru Tada, Junichiro Satomi, Tomoya Kinouchi, Kazuyuki Kuwayama, Kenji Yagi, Kohhei Nakajima, Nobuhisa Matsushita, Takeshi Miyamoto, Tadashi Yamaguchi, Kenji Shimada, Masaaki Korai, Hideo Mure, Y Okayama, Takashi Abe, Masafumi Harada, Keiko T. Kitazato and Yasuhisa Kanematsu :
Treatment of Unruptured Cerebral Aneurysms with the Mineralocorticoid Receptor Blocker Eplerenone-Pilot Study.,
Journal of Stroke & Cerebrovascular Diseases, Vol.27, No.8, 2134-2140, 2018.
(Tokushima University Institutional Repository: 115570,   DOI: 10.1016/j.jstrokecerebrovasdis.2018.03.008,   PubMed: 29622372,   Elsevier: Scopus)
11. Masaaki Korai, 北里 慶子, Yoshiteru Tada, Takeshi Miyamoto, Kenji Shimada, Nobuhisa Matsushita, Yasuhisa Kanematsu, Junichiro Satomi, 橋本 友紀 and Shinji Nagahiro :
Hyperhomocysteinemia induced by excessive methionine intake promotes rupture of cerebral aneurysms in ovariectomized rats,
Journal of Neuroinflammation, Vol.13, No.1, 165, 2016.
(Tokushima University Institutional Repository: 110031,   DOI: 10.1186/s12974-016-0634-3,   PubMed: 27349749)
12. Takeshi Miyamoto, DK Kung, KT Kitazato, Kenji Yagi, Kenji Shimada, Yoshiteru Tada, Masaaki Korai, Yoshitaka Kurashiki, Tomoya Kinouchi, Yasuhisa Kanematsu, Junichiro Satomi, T Hashimoto and Shinji Nagahiro :
Site-specific elevation of interleukin-1β and matrix metalloproteinase-9 in the Willis circle by hemodynamic changes is associated with rupture in a novel rat cerebral aneurysm model,
Journal of Cerebral Blood Flow and Metabolism, Vol.37, No.8, 2795-2805, 2016.
(Tokushima University Institutional Repository: 110032,   DOI: 10.1177/0271678X16675369,   PubMed: 27798272)
13. Kenji Shimada, Hjime Furukawa, Kousuke Wada, Masaaki Kohrai, Yuan Wei, Yoshiteru Tada, Atsushi Kuwahara, Fumiaki Shikata, Keiko T. Kitazato, Shinji Nagahiro, Michael T. Lawton and Tomoki Hashimoto :
Protective role of peroxisome proliferator-activated receptor- in the development of intracranial aneurysm rupture,
Stroke, Vol.46, No.6, 1664-1672, 2015.
(DOI: 10.1161/STROKEAHA.114.007722,   PubMed: 25931465,   Elsevier: Scopus)
14. Yoshiteru Tada, Kenji Yagi, Masaaki Uno, Nobuhisa Matsushita, Yasuhisa Kanematsu, Kazuyuki Kuwayama, Kenji Shimada, Kyoko Nishi, Motohiro Hirasawa, Junichiro Satomi, KT Kitazato, Teruyoshi Kageji, E Matsumura and Shinji Nagahiro :
Improvement of plasma biomarkers after switching stroke patients from other angiotensin II type I receptor blockers to olmesartan,
Journal of Stroke & Cerebrovascular Diseases, Vol.24, 1487-1492, 2015.
(DOI: 10.1016/j.jstrokecerebrovasdis.2015.03.015,   PubMed: 25891757,   Elsevier: Scopus)
15. Kenji Shimada, Hajime Furukawa, Kosuke Wada, Yuan Wei, Yoshiteru Tada, Atsushi Kuwabara, Fumiaki Shikata, Yasuhisa Kanematsu, Michael T. Lawton, Keiko T. Kitazato, Shinji Nagahiro and Tomoki Hashimoto :
Angiotensin-(1-7) protects against the development of aneurysmal subarachnoid hemorrhage in mice,
Journal of Cerebral Blood Flow and Metabolism, Vol.35, No.7, 1163-1168, 2015.
(DOI: 10.1038/jcbfm.2015.30,   PubMed: 25757758,   Elsevier: Scopus)
16. Yoshiteru Tada, Hiroshi Makino, Hajime Furukawa, Kenji Shimada, Kosuke Wada, EI Liang, Shoko Murakami, Mari Kudo, DK Kung, KT Kitazato, Shinji Nagahiro, MT Lawton and Tomoki Hashimoto :
Roles of estrogen in the formation of intracranial aneurysms in ovariectomized female mice,
Neurosurgery, Vol.75, No.6, 690-695, 2014.
(DOI: 10.1227/NEU.0000000000000528,   PubMed: 25181430,   Elsevier: Scopus)
17. Yoshiteru Tada, K Wada, Kenji Shimada, H Makino, EI Liang, S Murakami, M Kudo, F Shikata, RAP Silva, KT Kitazato, DM Hasan, Yasuhisa Kanematsu, Shinji Nagahiro and T Hashimoto :
Estrogen protects against intracranial aneurysm rupture in ovariectomized mice,
Hypertension, Vol.63, 1339-1344, 2014.
(DOI: 10.1161/HYPERTENSIONAHA.114.03300,   PubMed: 24732889)
18. Yoshiteru Tada, Wada Kosuke, Kenji Shimada, Makino Hiroshi, EI Liang, Murakami Shoko, Kudo Mari, KT Kitazato, Shinji Nagahiro and Hashimoto Tomoki :
Roles of hypertension in the rupture of intracranial aneurysms,
Stroke, Vol.45, No.2, 579-586, 2014.
(DOI: 10.1161/STROKEAHA.113.003072,   PubMed: 24370755,   Elsevier: Scopus)
19. Tomoya Kinouchi, Keiko T. Kitazato, Kenji Shimada, Kenji Yagi, Yoshiteru Tada, Nobuhisa Matsushita, Manabu Sumiyoshi, Junichiro Satomi, Teruyoshi Kageji and Shinji Nagahiro :
Activation of signal transducer and activator of transcription-3 by a peroxisome proliferator-activated receptor gamma agonist contributes to neuroprotection in the peri-infarct region after ischemia in oophorectomized rats,
Stroke, Vol.43, No.2, 478-483, 2012.
(DOI: 10.1161/STROKEAHA.111.618926,   PubMed: 22076002)
20. Nobuhisa Matsushita, Keiko T. Kitazato, Yoshiteru Tada, Manabu Sumiyoshi, Kenji Shimada, Kenji Yagi, Yasuhisa Kanematsu, Junichiro Satomi and Shinji Nagahiro :
Increase in body Na+-to-water ratio is associated with cerebral aneurysm formation in oophorectomized rats,
Hypertension, Vol.60, No.5, 1309-1315, 2012.
(DOI: 10.1161/HYPERTENSIONAHA.112.198762,   PubMed: 23045463)
21. Yoshiteru Tada, Keiko T. Kitazato, Kenji Yagi, Kenji Shimada, Nobuhisa Matsushita, Tomoya Kinouchi, Yasuhisa Kanematsu, Junichiro Satomi, Teruyoshi Kageji and Shinji Nagahiro :
Statins Promote the Growth of Experimentally Induced Cerebral Aneurysms in Estrogen-Deficient Rats,
Stroke, Vol.42, No.8, 2286-2293, 2011.
(DOI: 10.1161/STROKEAHA.110.608034,   PubMed: 21737796)
22. Kenji Shimada, Keiko T. Kitazato, Tomoya Kinouchi, Kenji Yagi, Yoshiteru Tada, Junichiro Satomi, Teruyoshi Kageji and Shinji Nagahiro :
Activation of estrogen receptor- and of angiotensin-converting enzyme 2 suppresses ischemic brain damage in oophorectomized rats.,
Hypertension, Vol.57, No.6, 1161-1166, 2011.
(DOI: 10.1161/HYPERTENSIONAHA.110.167650,   PubMed: 21536991)
23. Yoshiteru Tada, Kenji Yagi, Keiko T. Kitazato, Tetsuya Tamura, Tomoya Kinouchi, Kenji Shimada, Nobuhisa Matsushita, Norio Nakajima, Junichiro Satomi, Teruyoshi Kageji and Shinji Nagahiro :
Reduction of endothelial tight junction proteins is related to cerebral aneurysm formation in rats.,
Journal of Hypertension, Vol.28, No.9, 1883-1891, 2010.
(DOI: 10.1097/HJH;0b013e32833c2273,   PubMed: 20577123)
24. Yoshiteru Tada, Keiko T. Kitazato, Tetsuya Tamura, Kenji Yagi, Kenji Shimada, Tomoya Kinouchi, Junichiro Satomi, Shinji Nagahiro and Shinji Nagahiro :
Role of mineralocorticoid receptor on experimental cerebral aneurysms in rats.,
Hypertension, Vol.54, No.3, 552-557, 2009.
(DOI: 10.1161/HYPERTENSIONAHA.109.134130,   PubMed: 19620512)
25. Kenji Yagi, Keiko T. Kitazato, Masaaki Uno, Yoshiteru Tada, Tomoya Kinouchi, Kenji Shimada and Shinji Nagahiro :
Edaravone, a free radical scavenger, inhibits MMP-9-related brain hemorrhage in rats treated with tissue plasmininogen activator,
Stroke, Vol.40, No.2, 626-631, 2009.
(DOI: 10.1161/STROKEAHA.108.520262,   PubMed: 19095969)

Proceeding of International Conference:

1. Tadashi Yamaguchi, Keiko T Kitazato, Eiji Shikata, Idumi Yamaguchi, Takeshi Miyamoto, Masaaki Korai, Kenji Shimada, Yoshiteru Tada, Yasuhisa Kanematsu and Yasushi Takagi :
Pro-inflammatory response promoted by Porphyromonas gingivalis lipopolysaccharide enhances the rupture of experimental intracranial aneurysms.,
Brain and Brain PET2019, Yokohama, Jul. 2019.
2. Yuki Yamamoto, Nobuaki Yamamoto, K Kuroda, Yasuhisa Kanematsu, Masaaki Korai, Kenji Shimada, Yuishin Izumi and Yasushi Takagi :
High White Blood Cell Count is a Risk Factor for Contrast-Induced Nephropathy following Mechanical Thrombectomy,
The 5th European Stroke Organization Conference, ESOC 2019, Milan, May 2019.
3. Nobuaki Yamamoto, Yuki Yamamoto, Masaaki Korai, Kenji Shimada, Yasuhisa Kanematsu, Yuishin Izumi, Yasushi Takagi and Ryuji Kaji :
Hyperintense Signals on Arterial Spin-Labeled Imaging as a predictor for favorable outcome after Late Time Window Thrombectomy,
The 5th European Stroke Organization Conference, ESOC 2019, Milan, May 2019.
4. Tadashi Yamaguchi, Takeshi Miyamoto, Masaaki Korai, Kenji Shimada, Yoshiteru Tada, Yasuhisa Kanematsu, Junichiro Satomi, Shinji Nagahiro and Yasushi Takagi :
Estrogen deficiency activates inflammasome in a rat model of intracranial aneurysms,
11th World Stroke Congress 2018, Montreal, Oct. 2018.
5. Takeshi Miyamoto, Yoshiteru Tada, Kenji Shimada, Kenji Yagi, Masaaki Korai, Hidetsugu Maekawa, Tadashi Yamaguchi, Syotaro Soshioka, Tomoya Kinouchi, Yasuhisa Kanematsu, Junichiro Satomi and Shinji Nagahiro :
Pro-inflammatory Response Elicited by Porphyromonas Gingivalis Lipopolysaccharide Exacerbates the Rupture of Experimental Cerebral Aneurysms,
International Stroke Conference 2017, Houston, Feb. 2017.
6. Takeshi Miyamoto, Keiko Kitazato, Hidetsugu Maekawa, Tadashi Yamaguchi, Kenji Shimada, Kenji Yagi, Yoshiteru Tada, Yoshitaka Kurashiki, syotaro Yoshioka, Yasuhisa Kanematsu, Junichiro Satomi and Shinji Nagahiro :
Porphyromonas gingivalis lipopolysaccharide enhances the rupture of intracranial aneurysms in rats,
25th European Stroke Conference, Apr. 2016.
7. Yoshitaka Kurashiki, Keiko Kitazato, Kenji Shimada, Kenji Yagi, Yoshiteru Tada, Tomoya Kinouchi, Manabu Sumiyoshi, Takeshi Miyamoto, Tadashi Yamaguchi, Junichiro Satomi, Yoshihiro Uto and Shinji Nagahiro :
Activation of M2 macrophages in the late phase of cerebral ischemia may contribute to phagocytosis of infarct area and neurogenesis,
25th European Stroke Conference, Apr. 2016.
8. Takeshi Miyamoto, Masaaki Korai, David K. Kung, Keiko K. Kitazato, Kenji Shimada, Kenji Yagi, Yoshiteru Tada, Yoshitaka Kurashiki, Kazuyuki Kuwayama, Junichiro Satomi and Shinji Nagahiro :
Hemodynamic changes elicit the formation and rupture of experimental cerebral aneurysms,
International stroke conference, Nashville, Feb. 2015.
9. Masaaki Korai, Kenji Shimada and Tomoki Hashimoto :
Roles of macrophage PPARγ on intracranial aneurysmal rupture,
International stroke conference, Nashville, Feb. 2015.
10. Yoshitaka Kurashiki, Kenji Shimada, Kenji Yagi, Yoshiteru Tada, Manabu Sumiyoshi, 宮本 健志, Junichiro Satomi, Teruyoshi Kageji and Shinji Nagahiro :
Predominant Activation of M2 Macrophages by Group-specific Component Protein-derived Macrophage Activating,
INTERNATIONAL STROKE CONFERENCE 2015, Feb. 2015.
11. Masaaki Korai, Kenji Shimada, Yoshiteru Tada and Shinji Nagahiro :
INTERNATIONAL STROKE CONFERENCE 2015 Roles of Macrophage PPAR on Intracranial Aneurysmal Rupture,
INTERNATIONAL STROKE CONFERENCE 2015, Feb. 2015.
12. 宮本 健志, Masaaki Korai, Kenji Shimada, Kenji Yagi, Yoshiteru Tada, Yoshitaka Kurashiki, Kazuyuki Kuwayama, Junichiro Satomi and Shinji Nagahiro :
Hemodynamic Changes May Be Partly Attributable To The Formation And Rupture Of Aneurysms In A Rat Model,
INTERNATIONAL STROKE CONFERENCE 2015, Feb. 2015.
13. Yoshitaka Kurashiki, K.T Kitazato, Kung K David, Kenji Shimada, Kenji Yagi, Yoshiteru Tada, Nobuhisa Matsushita, Manabu Sumiyoshi, Junichiro Satomi, Y Uto and Shinji Nagahiro :
Effects of the immunostimulant GcMAF in cerebral ischemia,
Congress Of Neurological Surgeons 2013 Annual Meeting, San Francisco, Oct. 2013.
14. Masaaki Korai, David K Kung, K.T Kitazato, Nobuhisa Matsushita, Yoshiteru Tada, Kenji Yagi, Kenji Shimada, Yasuhisa Kanematsu, Junichiro Satomi and Shinji Nagahiro :
Role of hyperhomocysteinemia in the development of intracranial aneurysms,
Congress Of Neurological Surgeons 2013 Annual Meeting, San Francisco, Oct. 2013.
15. Tomoya Kinouchi, Yoshitaka Kurashiki, 北里 慶子, Kenji Shimada, Kenji Yagi, Yoshiteru Tada, Nobuhisa Matsushita, Manabu Sumiyoshi, Junichiro Satomi, Masataka Sata and Shinji Nagahiro :
Post-stroke PPAR activation promotes the proliferation and differentiation of innate- and bone marrow-derived stem cells insubventricular zone, leading to vasogenesis and neurogenesis in cortex,
International STROKE Conference 2013, Honolulu, Feb. 2013.
16. Nobuhisa Matsushita, Keiko T. Kitazato, Kenji Shimada, Tomoya Kinouchi, Manabu Sumiyoshi, Yasuhisa Kanematsu, Junichiro Satomi and Shinji Nagahiro :
Impact of high salt intake on the formation and growth of cerebral aneurysm,
The 5th International Aldosterone Forum in Japan, Tokyo, May 2012.
17. Masaaki Korai, Keiko T. Kitazato, Tomoya Kinouchi, Kenji Shimada, Nobuhisa Matsushita, Manabu Sumiyoshi, Yasuhisa Kanematsu, Junichiro Satomi, Teruyoshi Kageji and Shinji Nagahiro :
Activation of Nuclear Receptors on Neuroprotection after Experimental Cerebral Ischemia in Female Rats,
American Association of Neurologial Surgeons Annual Scientific Meeting, Miami, Apr. 2012.
18. Nobuhisa Matsushita, Keiko T. Kitazato, Kenji Shimada, Tomoya Kinouchi, Yasuhisa Kanematsu, Junichiro Satomi and Shinji Nagahiro :
Influence of sodium retention on the formation of cerebral aneurysm,
American Association of Neurologial Surgeons Annual Scientific Meeting, Miami, Apr. 2012.
19. Keiko T. Kitazato, Yoshiteru Tada, Tetsuya Tamura, Kenji Yagi, Kenji Shimada, Nobuhisa Matsushita, Tomoya Kinouchi, Yasuhisa Kanematsu, Junichiro Satomi, Teruyoshi Kageji and Shinji Nagahiro :
Vascular Mineralcorticoid Receptor Antagonism Combined with A Decrease in Salt-intake By Eplerenone Inhibits Cerebral Aneurysm without Affecting Blood Pressure,
International Stroke Conference 2011, LosAngels, Feb. 2012.
20. KT Kitazato, Yoshiteru Tada, Tetsuya Tamura, Kenji Yagi, Kenji Shimada, Nobuhisa Matsushita, Tomoya Kinouchi, Yasuhisa Kanematsu, Junichiro Satomi, Teruyoshi Kageji and Shinji Nagahiro :
Vascular mineralcorticoid receptor antagonism combined with a decrease in salt-intake by eplerenone inhibits cerebral aneurysm without affecting blood pressure,
International Stroke Conference 2011, Los Angeles, Oct. 2011.
21. KT Kitazato, Tomoya Kinouchi, Kenji Shimada, Yoshiteru Tada, Nobuhisa Matsushita, Manabu Sumiyoshi, Yasuhisa Kanematsu, Junichiro Satomi, Teruyoshi Kageji and Shinji Nagahiro :
Role of Nuclear receptors on neuroprotection after experimental cerebral ischemia in female rats,
115th International Symposium on Cerebral Blood Flow Metabolism and Function, Barcelona, May 2011.
22. Manabu Sumiyoshi, Tomoya Kinouchi, T Tsutsumi, Keiko T. Kitazato, Kenji Shimada, Nobuhisa Matsushita, Yasuhisa Kanematsu, Junichiro Satomi and Shinji Nagahiro :
High salt intake under hypoestrogenecity deteriorates ischemic brain damage without affecting blood pressure,
115th International Symposium on Cerebral Blood Flow,Metabolism,and Function, Barcelona, May 2011.
23. Kenji Shimada, Keiko T. Kitazato, Tomoya Kinouchi, Kenji Yagi, Yoshiteru Tada, Junichiro Satomi, Teruyoshi Kageji and Shinji Nagahiro :
Activation of estrogen receptor a and of ace2 suppresses ischemic brain damage in oophorectomized rats,
115th International Symposium on Cerebral Blood Flow,Metabolism,and Function, Barcelona, May 2011.
24. Kenji Shimada, Keiko T. Kitazato, Tomoya Kinouchi, Kenji Yagi, Yoshiteru Tada, Junichiro Satomi, Teruyoshi Kageji and Shinji Nagahiro :
Up-regulation of estrogen receptor alpha with down-regulation of the brain renin-angiotensin system by olmesartan contributes to neuroprotection against cerebral infarction in estrogen-deficient rats,
International Stroke Conference 2011, Los Angeles, Feb. 2011.
25. Kenji Shimada, Keiko T. Kitazato, Tomoya Kinouchi, Kenji Yagi, Yoshiteru Tada, Junichiro Satomi, Teruyoshi Kageji and Shinji Nagahiro :
Activation of estrogen receptor and inhibition of local renin angiotensin system against cerebral ischenmia in oophorectomized rats,
The 1st World Forum on Cerebral Blood Flow Metabolism & Function, Kyoto, Oct. 2010.
26. Kenji Shimada, Tomoya Kinouchi, KT Kitazato, Yoshiteru Tada, Kenji Yagi, Teruyoshi Kageji and Shinji Nagahiro :
Role of Estrogen receptors in cerebral ischemia in female rats; Contribution of angiotensintype 1 receptor blocker,
XIV World Congress of Neurological Surgery, Boston, Aug. 2009.
27. Tomoya Kinouchi, Keiko T. Kitazato, Kenji Yagi, Kenji Shimada, Yoshiteru Tada, Junichiro Satomi, Teruyoshi Kageji and Shinji Nagahiro :
Pioglitazone promotes neuroprotection through the activation of STAT3 against cerebral ischemia in female rats,
XIV World Congress of Neurological Surgery, Boston, Aug. 2009.
28. Yoshiteru Tada, Keiko T. Kitazato, Tetsuya Tamura, Kenji Yagi, Kenji Shimada, Tomoya Kinouchi, Nobuhisa Matsushita, Junichiro Satomi and Shinji Nagahiro :
Eplerenone Suppresses the Progression of Experimentally-induced Cerebral Aneurysms in Rats,
XIV World Congress of Neurological Surgery, Boston, Aug. 2009.
29. Yoshiteru Tada, Keiko T. Kitazato, Tetsuya Tamura, Kenji Yagi, Kenji Shimada, Tomoya Kinouchi, Junichiro Satomi and Shinji Nagahiro :
Role of mineralocorticoid receptor on experimental cerebral aneurysms in rats,
The 6th International Intracranial Stent Meeting 2009, Sendai, Aug. 2009.

Proceeding of Domestic Conference:

1. Toshitaka Fujihara, Yoshiteru Tada, Kenji Shimada, Yasuhisa Kanematsu and Yasushi Takagi :
内頚動脈海綿静脈洞瘻に急性症候発作重積を合併した1例,
第14回日本てんかん学会中国・四国地方会, Feb. 2020.
2. 石原 学, Yasuhisa Kanematsu, Nobuaki Yamamoto, Shu Sogabe, Takeshi Miyamoto, Kenji Shimada, Yuki Yamamoto, Jun Oto and Yasushi Takagi :
NIHSS5点以下軽症脳主幹動脈閉塞症例における転帰,
第25回日本脳神経外科救急学会, Feb. 2020.
3. 山本 陽子, Yasuhisa Kanematsu, Shu Sogabe, Takeshi Miyamoto, Masaaki Korai, Kenji Shimada and Yasushi Takagi :
Neckからfetal typeのPcomが起始する大型血栓化IC-PC動脈瘤に対しステント併用下コイル塞栓術を行った一例,
第88回(一社)日本脳神経外科学会中国四国支部学術集会, Dec. 2019.
4. Tadashi Yamaguchi, Takeshi Miyamoto, 北里 慶子, Eiji Shikata, Idumi Yamaguchi, Masaaki Korai, Kenji Shimada, Yoshiteru Tada, Yasuhisa Kanematsu and Yasushi Takagi :
エストロゲン欠乏脳動脈瘤ラットモデルにおけるERαの低下とNLRP3 inflammasome活性の関係,
第62回日本脳循環代謝学会学術集会, Nov. 2019.
5. Yuki Yamamoto, Nobuaki Yamamoto, Yasuhisa Kanematsu, Manabu Ishihara, Takeshi Miyamoto, Masaaki Korai, Kenji Shimada, Hideo Mure, Yasushi Takagi and Yuishin Izumi :
転倒後の脳脊髄液減少症に上矢状静脈洞血栓症を合併し, 血管内治療をおこなった一例,
第35回日本脳神経血管内治療学会学術総会, Nov. 2019.
6. Kenji Shimada, Koichi Satoh, Taku Matsuda, Takeshi Miyamoto, Masaaki Korai, Yasuhisa Kanematsu and Yasushi Takagi :
Targeting‌embolizationを行わず,流出路をコイル塞栓することにより舌下神経障害なく 治療し得た‌ACC‌dAVFの1例,
第35回日本脳神経血管内治療学会学術総会, Nov. 2019.
7. Yasuhisa Kanematsu, Kenji Shimada, Masaaki Korai, Takeshi Miyamoto, Yoshiteru Tada, Yuki Yamamoto, Nobuaki Yamamoto, Junichiro Satomi and Yasushi Takagi :
当院での急性期脳底動脈閉塞に対する血管内治療成績,
第35回日本脳神経血管内治療学会学術総会, Nov. 2019.
8. Taku Matsuda, Kenji Shimada, Takeshi Miyamoto, Takashi Abe, Masaaki Korai, Yasuhisa Kanematsu and Yasushi Takagi :
T1-CUBEが有効であった頭蓋内動脈解離の2例,
日本脳神経外科学会第78回学術集会, Oct. 2019.
9. Manabu Ishihara, Yasuhisa Kanematsu, Nobuaki Yamamoto, Takeshi Miyamoto, Masaaki Korai, Kenji Shimada, Yuki Yamamoto, Jun Oto and Yasushi Takagi :
NIHSS 5点以下の軽症脳主幹動脈閉塞症例における予後因子,
日本脳神経外科学会第78回学術集会, Oct. 2019.
10. Tadashi Yamaguchi, Takeshi Miyamoto, 北里 慶子, Eiji Shikata, Idumi Yamaguchi, Masaaki Korai, Kenji Shimada, Yoshiteru Tada, Yasuhisa Kanematsu and Yasushi Takagi :
脳動脈瘤破裂モデルにおける部位特異的な早期形態変化と血管崩壊関連分子の変動,
日本脳神経外科学会第78回学術集会, Oct. 2019.
11. Yasuhisa Kanematsu, Kenji Shimada, Masaaki Korai, Takeshi Miyamoto, Idumi Yamaguchi, Tadashi Yamaguchi, Yoshiteru Tada, Junichiro Satomi, Shinji Nagahiro and Yasushi Takagi :
当院における急性期脳底動脈閉塞に対する治療成績,
日本脳神経外科学会第78回学術集会, Oct. 2019.
12. Takeshi Miyamoto, 北里 慶子, Yoshiteru Tada, Kenji Shimada, Masaaki Korai, Tadashi Yamaguchi, Yasuhisa Kanematsu and Yasushi Takagi :
Porphyromonas gingivalis LPSは脳動脈瘤モデルラットにおいて脳動脈瘤破裂を促進する,
日本脳神経外科学会第78回学術集会, Oct. 2019.
13. Idumi Yamaguchi, Yasuhisa Kanematsu, Kenji Shimada, Masaaki Korai, Takeshi Miyamoto, 北里 慶子, Nobuaki Yamamoto, 山本 雄貴 and Yasushi Takagi :
Retrospective analysis of risk factor associated with worse outcome of in-hospital ischemic stroke,
Neurologia Medico-Chirurgica, Oct. 2019.
14. Nobuaki Yamamoto, Yuki Yamamoto, Manabu Ishihara, Takeshi Miyamoto, Kenji Shimada, Yasuhisa Kanematsu, Yuishin Izumi and Yasushi Takagi :
血行再建術前における経静脈的造影剤投与によるFlat panel CTAの有用性,
中四国脳卒中研究会, Sep. 2019.
15. Nobuaki Yamamoto, Kazutaka Kuroda, Yuki Yamamoto, Manabu Ishihara, Masaaki Korai, Kenji Shimada, Yasuhisa Kanematsu, Yuishin Izumi and Yasushi Takagi :
Tandem Occlusion患者に対する血管内治療(Simultaneous Approach),
第44回日本脳卒中学会学術集会, Mar. 2019.
16. Yuki Yamamoto, Nobuaki Yamamoto, Kazutaka Kuroda, Masaaki Korai, Toshiyuki Okazaki, Kenji Shimada, Yasuhisa Kanematsu, Yuishin Izumi and Yasushi Takagi :
血栓回収療法後の造影剤腎症は白血球数高値と関連する,
第44回日本脳卒中学会学術集会, Mar. 2019.
17. Kyoko Nishi, Yasuhisa Kanematsu, Masaaki Korai, Toshiyuki Okazaki, Kenji Shimada, Nobuaki Yamamoto, Hideyuki Takano, Shinsuke Katoh and Yasushi Takagi :
徳島大学病院脳卒中センター (SCU)の 多職種連携による医療人育成,
日本脳卒中学会2019, Mar. 2019.
18. Yuki Yamamoto, Nobuaki Yamamoto, Kazutaka Kuroda, 福本 竜也, Manabu Ishihara, Masaaki Korai, Kenji Shimada, Yasuhisa Kanematsu, Yuishin Izumi and Yasushi Takagi :
治療後に症状増悪した上矢状静脈洞血栓症の一例,
第8回脳血管内治療四国遍路塾, Mar. 2019.
19. Yuki Yamamoto, Kazutaka Kuroda, Nobuaki Yamamoto, Hiroshi Kagusa, Masaaki Korai, Kenji Shimada, Yasuhisa Kanematsu, Yuishin Izumi and Yasushi Takagi :
頭癌治療中に内頚動脈閉塞を認めた1例,
第21回徳島脳血管障害カンファレンス, Mar. 2019.
20. Yuki Yamamoto, Nobuaki Yamamoto, Kazutaka Kuroda, Masaaki Korai, Toshiyuki Okazaki, Kenji Shimada, Yasuhisa Kanematsu, Yuishin Izumi and Yasushi Takagi :
塞栓回収療法後の造影剤腎症についての検討,
第21回徳島脳卒中研究会, Feb. 2019.
21. Masaaki Korai, Junichiro Satomi, Yuki Yamamoto, Nobuaki Yamamoto, Toshiyuki Okazaki, Kenji Shimada, Yasuhisa Kanematsu and Yasushi Takagi :
Borden type 1横・S状静脈洞部硬膜動静脈瘻に対するバルーン支援下選択的経静脈塞栓術,
第34回日本脳神経血管内治療学会学術総会, Nov. 2018.
22. Kenji Shimada, 大谷 誠, Yasuhisa Kanematsu and Yasushi Takagi :
DPCを用いた疫学的調査による我が国の硬膜動静脈瘻の現状,
第34回日本脳神経血管内治療学会学術総会, Nov. 2018.
23. Kenji Shimada, 佐藤 裕一, 羽星 辰哉, 花岡 真実, 仁木 均, Kazuhito Matsuzaki, Koichi Satoh, 三宅 一 and Yasushi Takagi :
急性期脳梗塞に対するstent retrieverと吸引カテーテルを併用した血栓回収療法―従来の治療法との比較検討―,
日本脳神経外科学会第77回学術総会, Oct. 2018.
24. Masaaki Korai, Junichiro Satomi, Yasuhisa Kanematsu, Hideo Mure, Kenji Shimada, Toshiyuki Okazaki and Yasushi Takagi :
硬膜動静脈瘻に対する直達術,
日本脳神経外科学会第77回学術総会, Oct. 2018.
25. Yasuhisa Kanematsu, Kenji Shimada, Masaaki Korai, Toshiyuki Okazaki, Yoshiteru Tada, Junichiro Satomi, Shinji Nagahiro and Yasushi Takagi :
当院における高齢者(80歳以上)くも膜下出血の治療成績と予後の検討,
日本脳神経外科学会第77回学術総会, Oct. 2018.
26. Toshiyuki Okazaki, Yasuhisa Kanematsu, Kenji Shimada, Masaaki Korai, Junichiro Satomi, Masaaki Uno and Yasushi Takagi :
当院におけるhemashield patchを使用した頸動脈内膜剥離術の長期成績の検討,
日本脳神経外科学会第77回学術総会, Oct. 2018.
27. Masaaki Korai, 羽星 辰哉, Yuki Yamamoto, Nobuaki Yamamoto, Toshiyuki Okazaki, Kenji Shimada, Yasuhisa Kanematsu and Yasushi Takagi :
脳腫瘍との鑑別を要した海綿静脈胴部硬膜動静脈瘻の一例,
脳血管内治療ブラッシュアップセミナー2018, Sep. 2018.
28. Takeshi Miyamoto, 山口 真司, K.Kung David, 北里 慶子, Yoshiteru Tada, Kenji Shimada, Kenji Yagi, Masaaki Korai, Yasuhisa Kanematsu, Junichiro Satomi and Shinji Nagahiro :
新規脳動脈瘤破裂モデルにおける破裂動脈瘤の病態解明,
第59回日本脳循環代謝学会学術集会, Nov. 2016.
29. Masaaki Korai, 北里 慶子, Yoshiteru Tada, Takeshi Miyamoto, Kenji Shimada, Kenji Yagi, Nobuhisa Matsushita, Yasuhisa Kanematsu, Junichiro Satomi and Shinji Nagahiro :
メチオニン過剰摂取による高ホモシステイン血症は崩壊しやすい特定脳動脈壁の炎症反応を増強し脳動脈瘤破裂を促進する,
第59回日本脳循環代謝学会学術集会, Nov. 2016.
30. 宮本 健志, Kung K David, 北里 慶子, 前川 秀継, Kenji Yagi, Kenji Shimada, Yoshiteru Tada, Yoshitaka Kurashiki, 吉岡 正太郎, Kazuyuki Kuwayama, Junichiro Satomi and Shinji Nagahiro :
ラット脳動脈瘤モデルにおける脳動脈瘤増大・破裂に及ぼす血行力学的負荷の影響,
第27回日本脳循環代謝学会, Oct. 2015.
31. Yoshitaka Kurashiki, 北里 慶子, Yoshiteru Tada, Kenji Yagi, Manabu Sumiyoshi, 宮本 健志, Kazuyuki Kuwayama, Junichiro Satomi, Kenji Shimada, Tomoya Kinouchi, Yoshihiro Uto and Shinji Nagahiro :
脳虚血後後期におけるGcMAF投与はM2 macrophageを増加させ神経再生に寄与する,
一般社団法人 日本脳神経外科学会第74回学術総会, Oct. 2015.
32. 宮本 健志, 北里 慶子, 前川 秀継, Kenji Yagi, Kenji Shimada, Yoshiteru Tada, Yoshitaka Kurashiki, 吉岡 正太郎, Kazuyuki Kuwayama, Junichiro Satomi, Shinji Nagahiro and K.Kung David :
ラット脳動脈瘤モデルにおける脳動脈瘤増大・破裂に及ぼす血行力学的負荷の影響,
一般社団法人 日本脳神経外科学会第74回学術総会, Oct. 2015.
33. Yoshiteru Tada, Kenji Yagi, 北里 慶子, Kazuyuki Kuwayama, Kenji Shimada, Junichiro Satomi, Shinji Nagahiro and 宇野 昌明 :
脳血管障害の既住がある高血圧症例に対するオルメサルタンの降圧効果と臓器保護作用,
一般社団法人 日本脳神経外科学会第74回学術総会, Oct. 2015.
34. Hideo Mure, Kenji Yagi, Shinji Nagahiro, Kenji Shimada and Kousaku Higashino :
引き抜き損傷後17年後に発症した脊髄くも膜嚢胞の一例,
第30回日本脊髄外科学会, Jun. 2015.
35. Manabu Sumiyoshi, Junichiro Satomi, 北里 慶子, 鈴江 涼子, Kenji Yagi, Kenji Shimada, Yoshiteru Tada, Kazuyuki Kuwayama and Shinji Nagahiro :
脳梗塞におけるHigh mobility group box-1シグナル活性化とエイコサペントエン酸による脳保護作用,
第2回日本心血管脳卒中学会学術集会, Jun. 2015.
36. Yoshitaka Kurashiki, 北里 慶子, Kenji Shimada, Kenji Yagi, Yoshiteru Tada, Tomoya Kinouchi, Manabu Sumiyoshi, Takeshi Miyamoto, Kazuyuki Kuwayama, Junichiro Satomi, Shinji Nagahiro and Yoshihiro Uto :
脳虚血後後期におけるGroup-specific protein-derived macrophage activating factor (GcMAF)投与は,M2 macrophage,
第2回日本心血管脳卒中学会学術集会, Jun. 2015.
37. 宮本 健志, Masaaki Korai, 北里 慶子, Kenji Shimada, Kenji Yagi, Yoshiteru Tada, Yoshitaka Kurashiki, Junichiro Satomi, Shinji Nagahiro and Kung K David :
ラットモデルにおける血行力学的変化と脳動脈瘤形成および破裂の関係,
第26回日本脳循環代謝学会, Nov. 2014.
38. Teruyoshi Kageji, Yoshitaka Kurashiki, 北里 慶子, Kenji Shimada, Kenji Yagi, Yoshiteru Tada, Tomoya Kinouchi, Manabu Sumiyoshi, 宮本 健志, Junichiro Satomi, 宇都 義弘 and Shinji Nagahiro :
虚血後後期におけ脳るGroup-specific protein-derived macrophage activating factor(GcMAF)によるM2 macrophage,
第26回日本脳循環代謝学会, Nov. 2014.
39. Tomoya Kinouchi, 北里 慶子, Kenji Shimada, Nobuhisa Matsushita, 岡﨑 敏之, Manabu Sumiyoshi and Shinji Nagahiro :
卵巣摘出ラットにおけるピオグリタゾンの脳虚血領域での神経再生促進効果について,
第37回日本脳卒中学会総会, Apr. 2012.
40. Nobuhisa Matsushita, 北里 慶子, Kenji Shimada, Yasuhisa Kanematsu, Junichiro Satomi and Shinji Nagahiro :
体内塩分貯留は脳動脈瘤形成の独立した危険因子である,
第37回日本脳卒中学会総会, Apr. 2012.
41. Nobuhisa Matsushita, 北里 慶子, Kenji Shimada, Tomoya Kinouchi, Yasuhisa Kanematsu, Junichiro Satomi and Shinji Nagahiro :
塩分過剰摂取は脳動脈瘤形成増大の独立した危険因子か?,
第36回日本脳卒中学会総会, Jul. 2011.
42. Tomoya Kinouchi, 北里 慶子, Kenji Shimada, Nobuhisa Matsushita, Junichiro Satomi and Shinji Nagahiro :
卵巣摘出ラットにおけるピオグリタゾンのSTAT3を介した脳虚血境界領域での神経保護作用のメカニズム,
第36回日本脳卒中学会総会, Jul. 2011.
43. Kenji Shimada, 北里 慶子, Tomoya Kinouchi, Kenji Yagi, Yoshiteru Tada, Junichiro Satomi, Teruyoshi Kageji and Shinji Nagahiro :
オルメサルタンによる脳梗塞抑制効果の新たなメカニズム;estrogen receptor αと脳内のRASの制御,
第36回日本脳卒中学会総会, Jul. 2011.
44. Kenji Shimada, 北里 慶子, Tomoya Kinouchi, Kenji Yagi, Yoshiteru Tada, Junichiro Satomi, Teruyoshi Kageji and Shinji Nagahiro :
卵巣摘出ラットにおけるオルメサルタンの組織RASの抑制を介した脳梗塞の抑制効果について,
第39回日本脳卒中の外科学会, Apr. 2010.
45. 片岡 芳規, Kenji Shimada, Hidehisa Horiguchi, Kazuhito Matsuzaki, Teruyoshi Kageji and Shinji Nagahiro :
第3脳室内巨大奇形種の1例,
第21回中国四国脳腫瘍研究会, Sep. 2007.
46. Kazuhito Matsuzaki, 友金 祐介, Kenji Shimada, Hideo Mure, Tetsuya Tamura, Hidehisa Horiguchi, Teruyoshi Kageji and Shinji Nagahiro :
定位脳組織生検の診断率と合併症,
第16回脳神経外科手術と機器学会, Apr. 2007.
47. Yoshiteru Tada, Ryoma Morigaki, Kenji Shimada, Atsuhiko Suzue, Kyoko Nishi, Masaaki Uno and Shinji Nagahiro :
急性期STA-MCA anastomosisの検討,
第36回日本脳卒中の外科学会, Mar. 2007.
48. Kenji Shimada, Kazuhito Matsuzaki, Teruyoshi Kageji, Shinji Nagahiro and 田代 敬 :
初診時髄腔内播腫を認めた成人脈絡叢乳頭腫の1例,
第24回日本脳腫瘍病理学会, Jun. 2006.

Et cetera, Workshop:

1. 鹿草 (名), 松田 拓, 石原 学, Masaaki Korai, Toshiyuki Okazaki, Kenji Shimada, Yasuhisa Kanematsu and Yasushi Takagi :
くも膜下出血で発症した,前方循環系の動脈解離,
第44回徳島脳神経外科談話会, Dec. 2018.
2. Hideo Mure, Kenji Shimada, Shinji Nagahiro, Kousaku Higashino and Koichi Sairyo :
引き抜き損傷後17年後に発症した脊髄くも膜嚢胞の一例,
第70回近畿脊髄外科研究会, Oct. 2014.
3. Junichiro Satomi, 羽星 辰哉, Kenji Shimada, 曽我部 周, Kazuyuki Kuwayama and Shinji Nagahiro :
大型内頚動脈瘤に対するhigh flow bypass,血管内手技を用いた治療戦略,
第19回四国脳神経外科カンファレンス, Aug. 2014.

Grants-in-Aid for Scientific Research (KAKEN Grants Database @ NII.ac.jp)

  • 脳動脈瘤破裂におけるinflammasome活性化とsirtuinの役割 (Project/Area Number: 20K09391 )
  • 歯周病巣のexosomeによる脳動脈瘤破裂への影響 (Project/Area Number: 20K09326 )
  • Intracranial aneurysms related to periodontal disease in basic- and clinical studies (Project/Area Number: 17K10832 )
  • Inflammasome activation induced rupture of intracranial aneurysms (Project/Area Number: 17K10831 )
  • Search by Researcher Number (60624351)