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Tokushima University > Graduate School of Biomedical Sciences > 歯学域 > Oral Science > Clinical Dentistry > Department of Conservative Dentistry >
Tokushima University > Faculty of Dentistry > Course in Dentistry > Clinical Dentistry for Oral Health and Function > Conservative Dentistry >
Tokushima University > University Hospital > Clinical Division > Department of General Dentistry > Conservative Dentistry >
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Academic Paper (Judged Full Paper):

1. Ikuko Hosokawa, Yoshitaka Hosokawa, Kazumi Ozaki and Takashi Matsuo :
Carnosic acid inhibits inflammatory cytokines production in human periodontal ligament cells.,
Immunopharmacology and Immunotoxicology, Vol.42, No.4, 373-378, 2020.
(DOI: 10.1080/08923973.2020.1782427,   PubMed: 32538208,   Elsevier: Scopus)
2. Yoshitaka Hosokawa, Ikuko Hosokawa, Kazumi Ozaki and Takashi Matsuo :
Sudachitin Inhibits Matrix Metalloproteinase-1 and -3 Production in Tumor Necrosis Factor-α-Stimulated Human Periodontal Ligament Cells.,
Inflammation, Vol.42, No.4, 1456-1462, 2019.
(DOI: 10.1007/s10753-019-01007-z,   PubMed: 30997585)
3. Ikuko Hosokawa, Yoshitaka Hosokawa, Kazumi Ozaki and Takashi Matsuo :
Carnosic Acid Inhibits CXCR3 Ligands Production in IL-27-Stimulated Human Oral Epithelial Cells.,
Inflammation, Vol.42, No.4, 1311-1316, 2019.
(DOI: 10.1007/s10753-019-00991-6,   PubMed: 30820808)
4. Satoru Shindo, Yoshitaka Hosokawa, Ikuko Hosokawa and Hideki Shiba :
Interleukin (IL)-35 Suppresses IL-6 and IL-8 Production in IL-17A-Stimulated Human Periodontal Ligament Cells.,
Inflammation, Vol.42, No.3, 835-840, 2019.
(DOI: 10.1007/s10753-018-0938-9,   PubMed: 30484005)
5. Yoshitaka Hosokawa, Ikuko Hosokawa, Kazumi Ozaki and Takashi Matsuo :
Honokiol and Magnolol Inhibit CXCL10 and CXCL11 Production in IL-27-Stimulated Human Oral Epithelial Cells.,
Inflammation, Vol.41, No.6, 2110-2115, 2018.
(DOI: 10.1007/s10753-018-0854-z,   PubMed: 30039429)
6. Yoshitaka Hosokawa, Ikuko Hosokawa, Kazumi Ozaki and Takashi Matsuo :
Transforming growth factor-β1 increases C-C chemokine ligand 11 production in interleukin 4-stimulated human periodontal ligament cells.,
Cell Biology International, Vol.42, No.10, 1395-1400, 2018.
(Tokushima University Institutional Repository: 112813,   DOI: 10.1002/cbin.11030,   PubMed: 29993161)
7. Yoshitaka Hosokawa, Ikuko Hosokawa, Kazumi Ozaki and Takashi Matsuo :
Effects of Theaflavin on Chemokine Production in TNF-α-stimulated Oral Epithelial Cells,
The Japanese Journal of Conservative Dentistry, Vol.61, No.1, 10-16, 2018.
8. Yoshitaka Hosokawa, Ikuko Hosokawa, Kazumi Ozaki and Takashi Matsuo :
IL-27 Modulates Chemokine Production in TNF- -Stimulated Human Oral Epithelial Cells.,
Cellular Physiology and Biochemistry, Vol.43, No.3, 1198-1206, 2017.
(Tokushima University Institutional Repository: 112954,   DOI: 10.1159/000481760,   PubMed: 28977795)
9. Yoshitaka Hosokawa, Ikuko Hosokawa, Satoru Shindo, Kazumi Ozaki and Takashi Matsuo :
IL-29 Enhances CXCL10 Production in TNF--stimulated Human Oral Epithelial Cells.,
Immunological Investigations, Vol.46, No.6, 615-624, 2017.
(Tokushima University Institutional Repository: 112817,   DOI: 10.1080/08820139.2017.1336176,   PubMed: 28753407)
10. Yoshitaka Hosokawa, Ikuko Hosokawa, Satoru Shindo, Kazumi Ozaki and Takashi Matsuo :
Gomisin N Decreases Inflammatory Cytokine Production in Human Periodontal Ligament Cells.,
Inflammation, Vol.40, No.2, 360-365, 2017.
(Tokushima University Institutional Repository: 112816,   DOI: 10.1007/s10753-016-0482-4,   PubMed: 27896541)
11. Yoshitaka Hosokawa, Ikuko Hosokawa, Satoru Shindo, Yoshihiro Ohta, Kazumi Ozaki and Takashi Matsuo :
Alkannin inhibits CCL3 and CCL5 production in human periodontal ligament cells.,
Cell Biology International, Vol.40, No.12, 1380-1385, 2016.
(Tokushima University Institutional Repository: 112812,   DOI: 10.1002/cbin.10692,   PubMed: 27743458)
12. Ikuko Hosokawa, Yoshitaka Hosokawa, Satoru Shindo, Kazumi Ozaki and Takashi Matsuo :
Melatonin Inhibits CXCL10 and MMP-1 Production in IL-1-Stimulated Human Periodontal Ligament Cells.,
Inflammation, Vol.39, No.4, 1520-1526, 2016.
(Tokushima University Institutional Repository: 112815,   DOI: 10.1007/s10753-016-0386-3,   PubMed: 27271323)
13. Satoru Shindo, Yoshitaka Hosokawa, Ikuko Hosokawa, Kazumi Ozaki and Takashi Matsuo :
Shikonin Inhibits Inflammatory Cytokine Production in Human Periodontal Ligament Cells.,
Inflammation, Vol.39, No.3, 1124-1129, 2016.
(Tokushima University Institutional Repository: 112814,   DOI: 10.1007/s10753-016-0344-0,   PubMed: 27072015)
14. Yoshitaka Hosokawa, Ikuko Hosokawa, Satoru Shindo, Kazumi Ozaki and Takashi Matsuo :
IL-4 Modulates CCL11 and CCL20 Productions from IL-1-Stimulated Human Periodontal Ligament Cells.,
Cellular Physiology and Biochemistry, Vol.38, No.1, 153-159, 2016.
(Tokushima University Institutional Repository: 112953,   DOI: 10.1159/000438617,   PubMed: 26765337)
15. Yoshitaka Hosokawa, Ikuko Hosokawa, Satoru Shindo, Kazumi Ozaki and Takashi Matsuo :
Calcitriol Suppressed Inflammatory Reactions in IL-1-Stimulated Human Periodontal Ligament Cells.,
Inflammation, Vol.38, No.6, 2252-2258, 2015.
(DOI: 10.1007/s10753-015-0209-y,   PubMed: 26156812,   Elsevier: Scopus)
16. Satoru Shindo, Yoshitaka Hosokawa, Ikuko Hosokawa, Kazumi Ozaki and Takashi Matsuo :
Genipin inhibits MMP-1 and MMP-3 release from TNF--stimulated human periodontal ligament cells.,
Biochimie, Vol.107PB, 391-395, 2014.
(Tokushima University Institutional Repository: 110103,   DOI: 10.1016/j.biochi.2014.10.008,   PubMed: 25457105,   Elsevier: Scopus)
17. Yoshitaka Hosokawa, Ikuko Hosokawa, Satoru Shindo, Kazumi Ozaki and Takashi Matsuo :
IL-22 Enhances CCL20 Production in IL-1-Stimulated Human Gingival Fibroblasts.,
Inflammation, Vol.37, No.6, 2062-2066, 2014.
(DOI: 10.1007/s10753-014-9939-5,   PubMed: 24902798,   Elsevier: Scopus)
18. Yoshitaka Hosokawa, Satoru Shindo, Ikuko Hosokawa, Kazumi Ozaki and Takashi Matsuo :
IL-6 trans-signaling enhances CCL20 production from IL-1-stimulated human periodontal ligament cells.,
Inflammation, Vol.37, No.2, 381-386, 2014.
(DOI: 10.1007/s10753-013-9750-8,   PubMed: 24081898,   Elsevier: Scopus)
19. Satoru Shindo, Yoshitaka Hosokawa, Ikuko Hosokawa, Kazumi Ozaki and Takashi Matsuo :
Genipin inhibits IL-1-induced CCL20 and IL-6 production from human periodontal ligament cells.,
Cellular Physiology and Biochemistry, Vol.33, No.2, 357-364, 2014.
(DOI: 10.1159/000356675,   PubMed: 24557363,   Elsevier: Scopus)
20. Yoshitaka Hosokawa, Ikuko Hosokawa, Satoru Shindo, Kazumi Ozaki and Takashi Matsuo :
(-)-Epigallocatechin-3-Gallate Inhibits CC Chemokine Ligand 11 Production in Human Gingival Fibroblasts.,
Cellular Physiology and Biochemistry, Vol.31, No.6, 960-967, 2013.
(DOI: 10.1159/000350114,   PubMed: 23839108)
21. Yoshitaka Hosokawa, Ikuko Hosokawa, Satoru Shindo, Kazumi Ozaki and Takashi Matsuo :
TLR3 agonist enhances CC chemokine ligand 20 production in IL-1-stimulated human gingival fibroblasts.,
Cellular Immunology, Vol.283, No.1-2, 8-11, 2013.
(DOI: 10.1016/j.cellimm.2013.05.005,   PubMed: 23850670)
22. Yoshitaka Hosokawa, Ikuko Hosokawa, Satoru Shindo, Kazumi Ozaki, Hideaki Nakae and Takashi Matsuo :
Tumor necrosis factor-like weak inducer of apoptosis increases CC chemokine ligand 20 production in interleukin 1-stimulated human gingival fibroblasts.,
Human Immunology, Vol.73, No.5, 470-473, 2012.
(DOI: 10.1016/j.humimm.2012.02.021,   PubMed: 22425737)
23. Yoshitaka Hosokawa, Ikuko Hosokawa, Kazumi Ozaki, Hideaki Nakae and Takashi Matsuo :
Interleukin (IL)-17A synergistically enhances CC chemokine ligand 20 production in IL-1-stimulated human gingival fibroblasts.,
Human Immunology, Vol.73, No.1, 26-30, 2012.
(DOI: 10.1016/j.humimm.2011.10.004,   PubMed: 22019504)
24. Yoshitaka Hosokawa, Ikuko Hosokawa, Satoru Shindo, Kazumi Ozaki, Tadashi Nakanishi, Hideaki Nakae and Takashi Matsuo :
Black tea polyphenol inhibits CXCL10 production in oncostatin M-stimulated human gingival fibroblasts.,
International Immunopharmacology, Vol.11, No.6, 670-674, 2011.
(DOI: 10.1016/j.intimp.2011.01.009,   PubMed: 21255696)
25. Yoshitaka Hosokawa, Ikuko Hosokawa, Kazumi Ozaki, Hideaki Nakae and Takashi Matsuo :
Oncostatin M synergistically induces CXCL10 and ICAM-1 expression in IL-1beta-stimulated-human gingival fibroblasts.,
Journal of Cellular Biochemistry, Vol.111, No.1, 40-48, 2010.
(DOI: 10.1002/jcb.22648,   PubMed: 20680966)
26. Yoshitaka Hosokawa, Ikuko Hosokawa, Kazumi Ozaki, Tadashi Nakanishi, Hideaki Nakae and Takashi Matsuo :
Tea polyphenols inhibit IL-6 production in tumor necrosis factor superfamily 14-stimulated human gingival fibroblasts.,
Molecular Nutrition & Food Research, Vol.54 Suppl 2, S151-8, 2010.
(DOI: 10.1002/mnfr.200900549,   PubMed: 20461739)
27. Yoshitaka Hosokawa, Ikuko Hosokawa, Kazumi Ozaki, Tadashi Nakanishi, Hideaki Nakae and Takashi Matsuo :
Catechins inhibit CXCL10 production from oncostatin M-stimulated human gingival fibroblasts,
The Journal of Nutritional Biochemistry, Vol.21, No.7, 659-664, 2010.
(DOI: 10.1016/j.jnutbio.2009.04.005,   PubMed: 19616927)
28. Ikuko Hosokawa, Yoshitaka Hosokawa, Kazumi Ozaki, Hiromichi Yumoto, Hideaki Nakae and Takashi Matsuo :
Proinflammatroy effects of muramyldipeptide on human gingival fibroblasts,
Journal of Periodontal Research, Vol.45, No.2, 193-199, 2010.
(DOI: 10.1111/j.1600-0765.2009.01217.x,   PubMed: 20470259)
29. Yoshitaka Hosokawa, Ikuko Hosokawa, Kazumi Ozaki, Hideaki Nakae and Takashi Matsuo :
TNFSF14 coordinately enhances CXCL10 and CXCL11 production from IFN-gamma-stimulated human gingival fibroblasts,
Molecular Immunology, Vol.47, No.4, 666-670, 2010.
(DOI: 10.1016/j.molimm.2009.10.018,   PubMed: 19939453)
30. Yoshitaka Hosokawa, Ikuko Hosokawa, Kazumi Ozaki, Tadashi Nakanishi, Hideaki Nakae and Takashi Matsuo :
Catechins Inhibit CCL20 Production in IL-17A-stimulated Human Gingival Fibroblasts,
Cellular Physiology and Biochemistry, Vol.24, No.5-6, 391-396, 2009.
(DOI: 10.1159/000257431,   PubMed: 19910679)
31. Yoshitaka Hosokawa, Ikuko Hosokawa, Kazumi Ozaki, Hideaki Nakae and Takashi Matsuo :
Human gingival fibroblasts express functional chemokine receptor CXCR6.,
Clinical and Experimental Immunology, Vol.156, No.3, 413-418, 2009.
(DOI: 10.1111/j.1365-2249.2009.03915.x,   PubMed: 19438592)
32. Yoshitaka Hosokawa, Ikuko Hosokawa, Kazumi Ozaki, Hideaki Nakae and Takashi Matsuo :
Cytokines differentially regulate CXCL10 production by interferon-gamma-stimulated or tumor necrosis factor-alpha-stimulated human gingival fibroblasts.,
Journal of Periodontal Research, Vol.44, No.2, 225-231, 2009.
(DOI: 10.1111/j.1600-0765.2008.01124.x,   PubMed: 18973545)
33. Yoshitaka Hosokawa, Ikuko Hosokawa, Kazumi Ozaki, Hideaki Nakae and Takashi Matsuo :
CC Chemokine ligand 17 in periodontal diseases: expression in diseased tissues and production by human gingival fibroblasts,
Journal of Periodontal Research, Vol.43, No.4, 471-477, 2008.
(DOI: 10.1111/j.1600-0765.2007.01080.x,   PubMed: 18557811)
34. Ikuko Hosokawa, Yoshitaka Hosokawa, Kazumi Ozaki, Hideaki Nakae and Takashi Matsuo :
Adrenomedullin suppresses tumour necrosis factor alpha-induced CXC chemokine ligand 10 production by human gingival fibroblasts.,
Clinical and Experimental Immunology, Vol.152, No.3, 568-575, 2008.
(DOI: 10.1111/j.1365-2249.2008.03647.x,   PubMed: 18435806)
35. Yoshitaka Hosokawa, Ikuko Hosokawa, Kazumi Ozaki, Hideaki Nakae and Takashi Matsuo :
CXC chemokine ligand 16 in periodontal diseases: expression in diseased tissues and production by cytokine-stimulated human gingival fibroblasts.,
Clinical and Experimental Immunology, Vol.149, No.1, 146-154, 2007.
(DOI: 10.1111/j.1365-2249.2007.03398.x,   PubMed: 17459077)
36. Yoshitaka Hosokawa, Ikuko Hosokawa, Kazumi Ozaki, Hideaki Nakae and Takashi Matsuo :
Proinflammatory effects of tumour necrosis factor-like weak inducer of apoptosis (TWEAK) on human gingival fibroblasts.,
Clinical and Experimental Immunology, Vol.146, No.3, 540-549, 2006.
(DOI: 10.1111/j.1365-2249.2006.03233.x,   PubMed: 17100776)
37. Ikuko Hosokawa, Yoshitaka Hosokawa, H Komatsuzawa, RB Goncalves, N Karimbux, MH Napimoga, Makoto Seki, K Ouhara, M Sugai, Martin A Taubman and Toshihisa Kawai :
Innate immune peptide LL-37 displays distinct expression pattern from beta-defensins in inflamed gingival tissue.,
Clinical and Experimental Immunology, Vol.146, No.2, 218-225, 2006.
(DOI: 10.1111/j.1365-2249.2006.03200.x,   PubMed: 17034573)
38. Yoshitaka Hosokawa, Ikuko Hosokawa, Kazumi Ozaki, Hideaki Nakae and Takashi Matsuo :
Cytokines differentially regulate ICAM-1 and VCAM-1 expression on human gingival fibroblasts.,
Clinical and Experimental Immunology, Vol.144, No.3, 494-502, 2006.
(DOI: 10.1111/j.1365-2249.2006.03064.x,   PubMed: 16734619)
39. Yoshitaka Hosokawa, Ikuko Hosokawa, Kazumi Ozaki, Hideaki Nakae and Takashi Matsuo :
Increase of CCL20 expression by human gingival fibroblasts upon stimulation with cytokines and bacterial endotoxin,
Clinical and Experimental Immunology, Vol.142, No.2, 285-291, 2005.
(DOI: 10.1111/j.1365-2249.2005.02912.x,   PubMed: 16232215)
40. Yoshitaka Hosokawa, Ikuko Hosokawa, Kazumi Ozaki, Hideaki Nakae, Keiji Murakami, Yoichiro Miyake and Takashi Matsuo :
CXCL12 and CXCR4 expression by human gingival fibroblasts in periodontal disease,
Clinical and Experimental Immunology, Vol.141, No.3, 467-474, 2005.
(DOI: 10.1111/j.1365-2249.2005.02852.x,   PubMed: 16045736)

Review, Commentary:

1. Yoichiro Miyake and Ikuko Hosokawa :
β-defensin と口腔内感染,
臨床と微生物, Vol.32, No.3, 269-273, May 2005.

Proceeding of International Conference:

1. Shindo Satoru, Yoshitaka Hosokawa, Ikuko Hosokawa, Kazumi Ozaki and Takashi Matsuo :
The effect of genipin on dendritic cells activation,
93rd General Session & Exhibition of the IADR, Boston, Mar. 2015.
2. Ikuko Hosokawa, Yoshitaka Hosokawa, Shindo Satoru, Kazumi Ozaki and Takashi Matsuo :
Melatonin inhibits inflammatory mediators productions in human periodontal ligament cells,
93rd General Session & Exhibition of the IADR, Boston, Mar. 2015.
3. Yoshitaka Hosokawa, Ikuko Hosokawa, Satoru Shindo, Kazumi Ozaki and Takashi Matsuo :
IL-4 modulates chemokine productions from IL-1-stimulated human periodontal ligament cells,
93rd General Session & Exhibition of the IADR, Boston, Mar. 2015.
4. Satoru Shindo, Yoshitaka Hosokawa, Ikuko Hosokawa and Takashi Matsuo :
The effect of genipin on MMP-1 and MMP-3 expression in IL-1beta-stimulated human periodontal ligament cells,
The 15th Joint Scientific Meeting of JSCD-KACD, Gyeongju, Korea, Nov. 2013.
5. Ikuko Hosokawa, Yoshitaka Hosokawa, Kazumi Ozaki, Hiromichi Yumoto, Hideaki Nakae and Takashi Matsuo :
Pro-inflammatory Roles of NOD2 in Human Gingival Fibroblasts,
The 3rd International Symposium on "Oral Sciences to Improve the Quality of Life", Tokushima, Sep. 2008.
6. Ikuko Hosokawa, Yoshitaka Hosokawa, Kazumi Ozaki, Hiromichi Yumoto, Hideaki Nakae and Takashi Matsuo :
Pro-inflammatory Roles of NOD2 in Human Gingival Fibroblasts,
86th General Session and Exhibition of the International Association for Dental Research, Toronto, Jul. 2008.
7. Yoshitaka Hosokawa, Ikuko Hosokawa, Kazumi Ozaki, Hideaki Nakae and Takashi Matsuo :
Th17 cytokines enhance CCL20 production by human gingival fibroblasts.,
86th General Session and Exhibition of the International Association for Dental Research, Toronto, Jun. 2008.
8. Ikuko Hosokawa, Yoshitaka Hosokawa, RB Goncalves, Martin A Taubman, NY Karimbux, Komatsuzawa Hitoshi and Toshihisa Kawai :
Expressinon of Antibacterial Peptides in Periodontal Disease,
82nd General Session and Exhibition of International Association for Dental Research, Honolulu, Mar. 2004.

Proceeding of Domestic Conference:

1. Ikuko Hosokawa, Yoshitaka Hosokawa, Kazumi Ozaki and Takashi Matsuo :
Carnosic acidはヒト口腔上皮細胞のIL-27誘導CXCR3リガンド産生を抑制する,
日本歯科保存学会2018年度秋季学術大会, Nov. 2018.
2. Yoshitaka Hosokawa, Ikuko Hosokawa, Kazumi Ozaki and Takashi Matsuo :
IL-27 induces CXCR3 ligands production in human oral epithelial cells,
第61回日本歯周病学会春季学術大会, Jun. 2018.
3. Yoshitaka Hosokawa, Ikuko Hosokawa, Kazumi Ozaki and Takashi Matsuo :
IL-29 enhances CXCL10 production in TNF-alpha-stimulated human oral epithelial cells,
第60回日本歯周病学会秋季学術大会, Dec. 2017.
4. Yoshitaka Hosokawa, Ikuko Hosokawa, Kazumi Ozaki and Takashi Matsuo :
IL-29 enahances CXCL10 production in human oral epithelial cells,
第60回日本歯周病学会春季学術大会, Oct. 2017.
5. Shindo Satoru, Ikeda Atsushi, Yoshitaka Hosokawa, Ikuko Hosokawa, Kazumi Ozaki and Takashi Matsuo :
Citrullinated vimentin promotes osteoclastgenesis,
日本歯科保存学会2016年度秋季学術大会, Oct. 2016.
6. Yoshitaka Hosokawa, Ikuko Hosokawa, Shindo Satoru, Kazumi Ozaki and Takashi Matsuo :
The effect of Gominsin N on inflammatory cytokine production in human periodontal ligament cells,
日本歯科保存学会2016年度秋季学術大会, Oct. 2016.
7. Yoshitaka Hosokawa, Ikuko Hosokawa, Satoru Shindo, Kazumi Ozaki and Takashi Matsuo :
The effect of alkannin on IL-6 and CCL20 production in human periodontal ligament cells,
第59回春季日本歯周病学会学術大会, May 2016.
8. Yoshitaka Hosokawa, Ikuko Hosokawa, Satoru Shindo, Kazumi Ozaki and Takashi Matsuo :
The effects of alkannin on CCR5 ligands production from human periodontal ligament cells,
日本歯科保存学会2015年度秋季学術大会, Nov. 2015.
9. Yoshitaka Hosokawa, Ikuko Hosokawa, Satoru Shindo, Kazumi Ozaki and Takashi Matsuo :
Effects of IL-4 on CCL11 and CCL20 productions in human periodontal ligament cells,
第58回秋季日本歯周病学会学術大会, Sep. 2015.
10. Shindo Satoru, Yoshitaka Hosokawa, Ikuko Hosokawa, Kazumi Ozaki and Takashi Matsuo :
Shikoninがヒト歯根膜由来細胞のIL-6およびIL-8産生に与える影響,
第141回日本歯科保存学会秋季学術大会, Oct. 2014.
11. Shindo Satoru, Yoshitaka Hosokawa, Ikuko Hosokawa, Kazumi Ozaki and Takashi Matsuo :
GenipinはE.coli LPSが誘導するヒト歯根膜細胞のIL-6およびIL-8産生を抑制する,
第140回日本歯科保存学会春季学術大会, Jun. 2014.
12. Yoshitaka Hosokawa, Ikuko Hosokawa, Satoru Shindo, Kazumi Ozaki and Takashi Matsuo :
活性型ビタミンDはIL-1β刺激ヒト歯根膜細胞の炎症性サイトカイン産生を抑制する,
第140回日本歯科保存学会春季学術大会, Jun. 2014.
13. Kitanaka Yutaro, Yoshitaka Hosokawa, Ikuko Hosokawa, Shindo Satoru, Kazumi Ozaki and Takashi Matsuo :
genipinはTNF-αが誘導するヒト歯根膜由来細胞のIL-6産生を抑制する,
第57回春季歯周病学会学術大会, May 2014.
14. 進藤 智, Yoshitaka Hosokawa, Ikuko Hosokawa, Kazumi Ozaki and Takashi Matsuo :
GenipinはIL-1betaが誘導するヒト歯根膜細胞のCCL20およびIL-6 産生を抑制する,
第139回日本歯科保存学会秋季学術大会, Oct. 2013.
15. Satoru Shindo, Yoshitaka Hosokawa, Ikuko Hosokawa, Kazumi Ozaki and Takashi Matsuo :
The effect of genipin on CCL20 and IL-6 productions from IL-1beta-stimulated human periodontal ligament cells,
The Japanese Journal of Conservative Dentistry, 70, Oct. 2013.
16. Yoshitaka Hosokawa, Ikuko Hosokawa, Satoru Shindo, Kazumi Ozaki and Takashi Matsuo :
IL-6 enhances CCL20 production from IL-1-stimulated human periodontal ligament cells,
Journal of the Japanese Association of Periodontology, 97, May 2013.
17. Ikuko Hosokawa, Yoshitaka Hosokawa, Kazumi Ozaki and Takashi Matsuo :
The effect of adrenomedullin on Th17-related cytokines production from human dendrtic cells,
The Japanese Journal of Conservative Dentistry, Nov. 2012.
18. Yoshitaka Hosokawa, Ikuko Hosokawa, Kazumi Ozaki, Hideaki Nakae and Takashi Matsuo :
The effect of IL-17A on CCL20 production from TNF-a-stimulated human gingival fibroblasts,
日本歯科保存学雑誌, Nov. 2012.
19. 石川 真琴, Kaya Yoshida, Natsumi Fujiwara, Yoshitaka Hosokawa, Ikuko Hosokawa and Kazumi Ozaki :
歯周病原性細菌Porphyromonas gingivalis感染が肝臓糖代謝に及ぼす影響,
日本歯科保存学雑誌, 155, Nov. 2012.
20. Yoshitaka Hosokawa, Ikuko Hosokawa, Kazumi Ozaki, Tadashi Nakanishi, Hideaki Nakae and Takashi Matsuo :
The effect of catechin on CCL11 production from TNF-alpha -stimulated human gingival fibroblasts,
The Japanese Journal of Conservative Dentistry, Jun. 2012.
21. Yoshitaka Hosokawa, Ikuko Hosokawa, Kazumi Ozaki, Hideaki Nakae and Takashi Matsuo :
The effect of IL-22 on CCL20 production in IL-1beta-stimulated human gingival fibroblasts,
Journal of the Japanese Association of Periodontology, May 2012.
22. Yoshitaka Hosokawa, Ikuko Hosokawa, Kazumi Ozaki, Tadashi Nakanishi and Takashi Matsuo :
The effect of TWEAK on CCL20 production on IL-1beta-stimulated human gingival fibroblasts,
The Japanese Journal of Conservative Dentistry, Oct. 2011.
23. Yoshitaka Hosokawa, Ikuko Hosokawa, Kazumi Ozaki, Tadashi Nakanishi, Hideaki Nakae and Takashi Matsuo :
The effect of theaflavin on IL-6 production in TNFSF14-stimulated human gingival fibroblasts,
The Japanese Journal of Conservative Dentistry, Jun. 2011.
24. Kazumi Ozaki, Natsumi Fujiwara, 石川 真琴, Ikuko Hosokawa, Yoshitaka Hosokawa and Hiromichi Yumoto :
う蝕関連細菌の家族内伝播と生活習慣による影響に関する研究 ―兄弟姉妹間の差異について―,
134回日本歯科保存学会春季学術大会, Jun. 2011.
25. Yoshitaka Hosokawa, Ikuko Hosokawa, Kazumi Ozaki, Hideaki Nakae and Takashi Matsuo :
TLR3 ligandがヒト歯肉線維芽細胞のIL-1beta誘導CCL20産生に与える影響,
Journal of the Japanese Association of Periodontology, May 2011.
26. Shindo Satoru, Yoshitaka Hosokawa, Ikuko Hosokawa, Kazumi Ozaki, Tadashi Nakanishi, Hideaki Nakae and Takashi Matsuo :
Oncostatin Mが誘導するヒト歯肉線維芽細胞のCXCL10産生に及ぼす紅茶ポリフェノールの影響,
Journal of the Japanese Association of Periodontology, May 2011.
27. Yoshitaka Hosokawa, Ikuko Hosokawa, Kazumi Ozaki, Tadashi Nakanishi, Hideaki Nakae and Takashi Matsuo :
The effect of catechin on IL-6 production from TNFSF14-stimulated human gingival fibroblasts,
The Japanese Journal of Conservative Dentistry, Oct. 2010.
28. Hashimoto Reina, Yoshitaka Hosokawa, Ikuko Hosokawa, Kazumi Ozaki, Tadashi Nakanishi, Hideaki Nakae and Takashi Matsuo :
IL-1betaが誘導するヒト歯肉線維芽細胞のCXCL10産生に及ぼす緑茶カテキンの影響,
Journal of the Japanese Association of Periodontology, Sep. 2010.
29. Hashimoto Reina, Yoshitaka Hosokawa, Ikuko Hosokawa, Kazumi Ozaki, Tadashi Nakanishi, Hideaki Nakae and Takashi Matsuo :
IL-1betaが誘導するヒト歯肉線維芽細胞のCXCL10産生に及ぼす緑茶カテキンの影響,
Journal of the Japanese Association of Periodontology, Sep. 2010.
30. Yoshitaka Hosokawa, Ikuko Hosokawa, Kazumi Ozaki, Hideaki Nakae and Takashi Matsuo :
IL-17A enhances CCL20 production in IL-1beta-stimulated human gingival fibroblasts,
Journal of the Japanese Association of Periodontology, May 2010.
31. Ikuko Hosokawa, Yoshitaka Hosokawa, Kazumi Ozaki, Hideaki Nakae and Takashi Matsuo :
Adrenomedullin inhibits CXCL10 production by human gingival fibroblasts,
56th Annual Meeting of Japanese Association for Dental Research, Nov. 2008.
32. Ikuko Hosokawa, Yoshitaka Hosokawa, Kazumi Ozaki, Hideaki Nakae and Takashi Matsuo :
Toll-like Receptor Ligands刺激が誘導する単球のCCL20産生に及ぼすAdrenomedullinの影響,
第128回日本歯科保存学会秋季学術大会, Nov. 2008.
33. Ikuko Hosokawa, Yoshitaka Hosokawa, Kazumi Ozaki, Hideaki Nakae and Takashi Matsuo :
ヒト歯肉線維芽細胞におけるTLR4 ligandが誘導するCXCL10産生に及ぼすAdrenomedullinの影響,
第51回日本歯周病学会秋季学術大会, Oct. 2008.
34. Ikuko Hosokawa, Yoshitaka Hosokawa, Kazumi Ozaki, Hideaki Nakae and Takashi Matsuo :
Toll-like Receptor Ligands刺激が誘導する単球のIL-1beta産生に及ぼすAdrenomedullinの影響,
第128回日本歯科保存学会春季学術大会, Jun. 2008.
35. Yoshitaka Hosokawa, Ikuko Hosokawa, Kazumi Ozaki, Hideaki Nakae and Takashi Matsuo :
Flagellinがヒト歯肉線維芽細胞のサイトカイン産生および接着分子発現に与える影響,
第128回日本歯科保存学会春季学術大会, Jun. 2008.
36. Ikuko Hosokawa, Yoshitaka Hosokawa, Kazumi Ozaki, Hideaki Nakae and Takashi Matsuo :
Adrenomedullinがヒト歯肉線維芽細胞のToll-like Receptor Ligands誘導サイトカイン産生に与える影響,
第51回日本歯周病学会春季学術大会, Apr. 2008.
37. Yoshitaka Hosokawa, Ikuko Hosokawa, Kazumi Ozaki, Hideaki Nakae and Takashi Matsuo :
Toll-like receptor ligandsがヒト歯肉線維芽細胞のCXCL10産生に与える影響,
第51回日本歯周病学会春季学術大会, Apr. 2008.
38. Ikuko Hosokawa, Yoshitaka Hosokawa, Kazumi Ozaki, Hideaki Nakae and Takashi Matsuo :
Adrenomedulinがヒト歯肉線維芽細胞のサイトカイン産生に与える影響の解析,
第127回日本歯科保存学会秋季学術大会, Nov. 2007.
39. Ikuko Hosokawa, Yoshitaka Hosokawa, Kazumi Ozaki, Hiromichi Yumoto, Hideaki Nakae and Takashi Matsuo :
Proinflammatory Roles of NOD2 in Human Gingival Fibroblasts,
第55回 国際歯科研究学会日本部会(JADR)総会・学術大会, Nov. 2007.
40. Yoshitaka Hosokawa, Ikuko Hosokawa, Kazumi Ozaki, Hideaki Nakae and Takashi Matsuo :
サイトカインがヒト歯肉線維芽細胞のCXCL10産生に与える影響,
日本歯周病学会50周年記念学術大会, Sep. 2007.
41. Yoshitaka Hosokawa, Ikuko Hosokawa, Kazumi Ozaki, Hideaki Nakae and Takashi Matsuo :
ヒト歯肉線維芽細胞におけるCCL17産生の解析,
第50回 春季日本歯周病学会学術大会, May 2007.
42. Yoshitaka Hosokawa, Ikuko Hosokawa, Kazumi Ozaki, Hideaki Nakae and Takashi Matsuo :
サイトカイン刺激によるヒト歯肉線維芽細胞におけるCXCL16産生の解析,
第36回 日本免疫学会総会・学術集会, Dec. 2006.
43. Yoshitaka Hosokawa, Ikuko Hosokawa, Kazumi Ozaki, Hideaki Nakae and Takashi Matsuo :
サイトカインがヒト歯肉線維芽細胞上のICAM-1およびVCAM-1発現に与える影響,
第49回 秋季日本歯周病学会学術大会, Oct. 2006.
44. Yoshitaka Hosokawa, Ikuko Hosokawa, Kazumi Ozaki, Hideaki Nakae and Takashi Matsuo :
TWEAKがヒト歯肉線維芽細胞における炎症性サイトカイン産生ならびに接着分子発現に与える影響の解析,
第49回 春季日本歯周病学会学術大会, Apr. 2006.
45. Yoshitaka Hosokawa, Ikuko Hosokawa, Hideaki Nakae, Kazumi Ozaki and Takashi Matsuo :
炎症性サイトカインおよびLPSはヒト歯肉線維芽細胞のCCL20産生を誘導する,
第48回 秋季日本歯周病学会学術大会, Sep. 2005.
46. Ikuko Hosokawa, Yoshitaka Hosokawa, Kazumi Ozaki and Takashi Matsuo :
Langerhans細胞における抗菌ペプチドの発現について,
第48回 秋季日本歯周病学会学術大会, Sep. 2005.
47. Yoshitaka Hosokawa, Ikuko Hosokawa, Kazumi Ozaki, Hideaki Nakae and Takashi Matsuo :
ヒト歯肉線維芽細胞におけるCXCL12産生ならびに機能的解析,
第47回 秋季日本歯周病学会学術大会, Oct. 2004.

Et cetera, Workshop:

1. Ikuko Hosokawa :
Adrenomedullinがヒト歯肉線維芽細胞のCXC chemokine ligand 10産生に与える影響,
先端歯学スクール2008, Oct. 2008.

Grants-in-Aid for Scientific Research (KAKEN Grants Database @ NII.ac.jp)

  • 柑橘類果皮含有生理活性物質を歯周炎治療に用いるための基礎的研究 (Project/Area Number: 19K10151 )
  • 口腔バイオフィルムの分散能と抗菌能を有する光触媒・ポリフェノール合剤の新規開発 (Project/Area Number: 19K10132 )
  • 香辛料含有成分を歯周炎治療に用いるための基礎的研究-ローズマリーに着目して- (Project/Area Number: 18K09600 )
  • Analysis of leukocyte infiltration mechanism to participate in inflammatory bone resorption in periodontal lesion (Project/Area Number: 16K11834 )
  • Development of the method for prevention of root caries with antibacterial ammonium hexafluorosilicate (Project/Area Number: 16K11553 )
  • role of melatonin in periodontal disease (Project/Area Number: 15K11392 )
  • The effect of adrenomedullin on Th17 cells in periodontal disease. (Project/Area Number: 25893158 )
  • Development of the method for prevention of dental caries with antibacterial ammonium hexafluorosilicate (Project/Area Number: 25462961 )
  • Search by Researcher Number (50707908)