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Tokushima University > Graduate School of Technology, Industrial and Social Sciences > Division of Bioscience and Bioindustry > Agroscience > 生物資源生産科学分野 >
Tokushima University > Faculty of Bioscience and Bioindustry > Department of Bioscience and Bioindustry > Biological Production Systems >
Tokushima University > Research Clusters > Research Clusters (Specified) > 1701001 新規ゲノム編集技術による糖尿病モデルブタの開発 >
Tokushima University > Research Clusters > Research Clusters (Registered) > 1704039 糖尿病の根治を目指す細胞治療プラットフォームの構築 >
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Academic Paper (Judged Full Paper):

1. Namula Zhao, Manita Wittayarat, Maki Hirata, Hirano Takayuki, Nguyen Thi Nhien, Le Anh Quynh, Fahrudin Mokhamad, Fuminori Tanihara and Takeshige Otoi :
Genome mutation after the introduction of the gene editing by electroporation of Cas9 protein (GEEP) system into bovine putative zygotes,
In Vitro Cellular & Developmental Biology. Animal, 2019.
(DOI: 10.1007/s11626-019-00385-w,   PubMed: 31297696)
2. Fuminori Tanihara, Maki Hirata, Morikawa Shigeki, Thi Nhien Nguyen, Quynh Anh Le, Hirano Takayuki, Fukumi Yoshiyuki, Abe Toshiaki and Takeshige Otoi :
The effects of electroporation on viability and quality of in vivo-derived bovine blastocysts,
The Journal of Reproduction and Development, 2019.
(DOI: 10.1262/jrd.2019-049,   PubMed: 31178553)
3. Fuminori Tanihara, Maki Hirata, Satoru Iizuka, Shinya Sairiki, Masahiro Nii, Nhien Thi Nguyen, Quynh Anh Le, Takayuki Hirano and Takeshige Otoi :
Relationship among ovarian follicular status, developmental competence of oocytes, and anti-M llerian hormone levels: A comparative study in Japanese wild boar crossbred gilts and Large White gilts.,
Animal Science Journal, Vol.90, No.6, 712-718, 2019.
(DOI: 10.1111/asj.13200,   PubMed: 30977253)
4. Nhien Nguyen Thi, Maki Hirata, Fuminori Tanihara, Takayuki Hirano, Quynh Anh Le, Masahiro Nii and Takeshige Otoi :
Hypothermic storage of porcine zygotes in serum supplemented with chlorogenic acid.,
Reproduction in Domestic Animals = Zuchthygiene, Vol.54, No.5, 750-755, 2019.
(DOI: 10.1111/rda.13417,   PubMed: 30788874,   Elsevier: Scopus)
5. Zhao Namula, Fuminori Tanihara, Manita Wittayarat, Maki Hirata, Nhien Thi Nguyen, Takayuki Hirano, Quynh Anh Le, Masahiro Nii and Takeshige Otoi :
Effects of Tris (hydroxymethyl) aminomethane on the quality of frozen-thawed boar spermatozoa.,
Acta Veterinaria Hungarica, Vol.67, No.1, 106-114, 2019.
(DOI: 10.1556/004.2019.012,   PubMed: 30922097)
6. Maki Hirata, Fuminori Tanihara, Manita Wittayarat, Takayuki Hirano, Nhien Thi Nguyen, Quynh Anh Le, Zhao Namula, Masahiro Nii and Takeshige Otoi :
Genome mutation after introduction of the gene editing by electroporation of Cas9 protein (GEEP) system in matured oocytes and putative zygotes.,
In Vitro Cellular & Developmental Biology. Animal, Vol.55, No.4, 237-242, 2019.
(DOI: 10.1007/s11626-019-00338-3,   PubMed: 30820813)
7. Fuminori Tanihara, Maki Hirata, Nhien Thi Nguyen, Quynh Anh LE, Takayuki Hirano and Takeshige Otoi :
Effects of concentration of CRISPR/Cas9 components on genetic mosaicism in cytoplasmic microinjected porcine embryos.,
The Journal of Reproduction and Development, Vol.65, No.3, 209-214, 2019.
(DOI: 10.1262/jrd.2018-116,   PubMed: 30726783,   Elsevier: Scopus)
8. Fuminori Tanihara, Maki Hirata, Nhien T. Nguyen, Quynh A. Le, Takayuki Hirano, Tatsuya Takemoto, Michiko Nakai, Dai-Ichiro Fuchimoto and Takeshige Otoi :
Generation of PDX-1 mutant porcine blastocysts by introducing CRISPR/Cas9-system into porcine zygotes via electroporation.,
Animal Science Journal, Vol.90, No.1, 55-61, 2018.
(DOI: 10.1111/asj.13129,   PubMed: 30368976)
9. Fuminori Tanihara, Maki Hirata, Nhien Thi Nguyen, Quynh Anh Le, Takayuki Hirano, Tatsuya Takemoto, Michiko Nakai, Dai-Ichiro Fuchimoto and Takeshige Otoi :
Generation of a TP53-modified porcine cancer model by CRISPR/Cas9-mediated gene modification in porcine zygotes via electroporation.,
PLoS ONE, Vol.13, No.10, e0206360, 2018.
(Tokushima University Institutional Repository: 112917,   DOI: 10.1371/journal.pone.0206360,   PubMed: 30352075)
10. Maki Hirata, Fuminori Tanihara, Masayasu Taniguchi, Mitsuhiro Takagi, Tsukasa Terazono and Takeshige Otoi :
Follicular development of canine ovaries stimulated by a combination treatment of eCG and hCG.,
Veterinary Medicine and Science, 2018.
(DOI: 10.1002/vms3.121,   PubMed: 30273973)
11. Maki Hirata, Fuminori Tanihara, Taniguchi Masayasu, Takagi Mitsuhiro, Terazono Tsukasa and Takeshige Otoi :
Viability of canine ovaries autografted to different peripheral sites,
The International Journal of Applied Research in Veterinary Medicine, Vol.16, No.2, 140-148, 2018.
12. Zhao Namula, Maki Hirata, Manita Wittayarat, Fuminori Tanihara, Nhien Nguyen Thi, Takayuki Hirano, Masahiro Nii and Takeshige Otoi :
Effects of chlorogenic acid and caffeic acid on the quality of frozen-thawed boar sperm.,
Reproduction in Domestic Animals = Zuchthygiene, 2018.
(DOI: 10.1111/rda.13288,   PubMed: 30053311)
13. Tetsushi Ono, Mitsuhiro Takagi, Chiho Kawashima, B Missaka P Wijayagunawardane, M Peter L A Vos, Masayasu Taniguchi, Fuminori Tanihara and Takeshige Otoi :
Comparative Effects of Different Dosages of hCG on Follicular Development in Postpartum Dairy Cows With Cystic Ovarian Follicles.,
Frontiers in Veterinary Science, Vol.5, 2018.
(DOI: 10.3389/fvets.2018.00130,   PubMed: 30009161)
14. Thanh-Van Nguyen, Manita Wittayarat, Kim Lanh Thi Do, Van Thanh Nguyen, Masahiro Nii, Zhao Namula, Toshiki Kunihara, Fuminori Tanihara, Maki Hirata and Takeshige Otoi :
Effects of chlorogenic acid (CGA) supplementation during in vitro maturation culture on the development and quality of porcine embryos with electroporation treatment after in vitro fertilization.,
Animal Science Journal, Vol.89, No.8, 1207-1213, 2018.
(DOI: 10.1111/asj.13049,   PubMed: 29806122)
15. Fuminori Tanihara, Maki Hirata, Thi Nguyen Nhien, Takayuki Hirano, Toshiki Kunihara and Takeshige Otoi :
Effect of ferulic acid supplementation on the developmental competence of porcine embryos during in vitro maturation.,
The Journal of Veterinary Medical Science, Vol.80, No.6, 1007-1011, 2018.
(DOI: 10.1292/jvms.18-0131,   PubMed: 29769451)
16. Shimazaki Megumi, Urasoko Saki, Tanaka Masako, Sato Yoko, Fuminori Tanihara, Maki Hirata, Taniguchi Masayasu, Takagi Mitsuhiro and Takeshige Otoi :
Effects of Orvus Es Paste (OEP) on the viability of bull spermatozoa after double freezing and thawing,
The International Journal of Applied Research in Veterinary Medicine, Vol.16, No.1, 32-38, 2018.
17. V T Nguyen, Fuminori Tanihara, Maki Hirata, Takayuki Hirano, Katsutoshi Nishio, T Do L Kim, V T Nguyen, M Nii and Takeshige Otoi :
Effects of Antifreeze Protein Supplementation on the Development of Porcine Morulae Stored at Hypothermic Temperatures.,
Cryo Letters, Vol.39, No.2, 131-136, 2018.
(PubMed: 29734422,   Elsevier: Scopus)
18. Katsutoshi Nishio, Fuminori Tanihara, T-V Nguyen, Toshiki Kunihara, M Nii, Maki Hirata, Tatsuya Takemoto and Takeshige Otoi :
Effects of voltage strength during electroporation on the development and quality of in vitro-produced porcine embryos.,
Reproduction in Domestic Animals = Zuchthygiene, Vol.53, No.2, 313-318, 2017.
(DOI: 10.1111/rda.13106,   PubMed: 29135047)
19. T-V Nguyen, Fuminori Tanihara, Ltk Do, Y Sato, M Taniguchi, M Takagi, T Nguyen Van and Takeshige Otoi :
Chlorogenic acid supplementation during in vitro maturation improves maturation, fertilization and developmental competence of porcine oocytes.,
Reproduction in Domestic Animals = Zuchthygiene, Vol.52, No.6, 969-975, 2017.
(DOI: 10.1111/rda.13005,   PubMed: 28660662)
20. Katsutoshi Nishio, Mado Yamazaki, Masayasu Taniguchi, Kazuhiko Besshi, Fumio Morita, Toshiki Kunihara, Fuminori Tanihara, Tatsuya Takemoto and Takeshige Otoi :
Sensitivity of the meiotic stage to hyperthermia during in vitro maturation of porcine oocytes.,
Acta Veterinaria Hungarica, Vol.65, No.1, 115-123, 2017.
(DOI: 10.1556/004.2017.012,   PubMed: 28244334)
21. Fuminori Tanihara, Tatsuya Takemoto, Eri Kitagawa, Shengbin Rao, Kim Lanh Thi Do, Akira Onishi, Yukiko Yamashita, Chisato Kosugi, Hitomi Suzuki, Shoichiro Sembon, Shunichi Suzuki, Michiko Nakai, Masakazu Hashimoto, Akihiro Yasue, Munehide Matsuhisa, Sumihare Noji, Tatsuya Fujimura, Dai-Ichiro Fuchimoto and Takeshige Otoi :
Somatic cell reprogramming-free generation of genetically modified pigs.,
Science Advances, Vol.2, No.9, 2016.
(Tokushima University Institutional Repository: 110154,   DOI: 10.1126/sciadv.1600803,   PubMed: 27652340)
22. L Do, M Wittayarat, T Terazono, Y Sato, M Taniguchi, Fuminori Tanihara, Tatsuya Takemoto, Y Kazuki, K Kazuki, M Oshimura and Takeshige Otoi :
Effects of duration of electric pulse on in vitro development of cloned cat embryos with human artificial chromosome vector.,
Reproduction in Domestic Animals = Zuchthygiene, Vol.51, No.6, 1039-1043, 2016.
(DOI: 10.1111/rda.12766)
23. N Kurniani Karja Wayan, M Fahrudin, MA Setiadi, LI Tumbelaka, R Sudarwati, YT Hastuti, BH Mulia, A Widianti, K Sultan, T Terazono, Z Namula, M Taniguchi, Fuminori Tanihara, Tatsuya Takemoto, K Kikuchi, Y Sato and Takeshige Otoi :
Characteristics and fertility of sumatran tiger spermatozoa cryopreserved with different sugars.,
Cryo Letters, Vol.37, No.4, 264-271, 2016.
(PubMed: 27925009,   Elsevier: Scopus)
24. M Nakai, J Ito, N Kashiwazaki, NT Men, Fuminori Tanihara, J Noguchi, H Kaneko, A Onishi and K Kikuchi :
Treatment with protein kinase C activator is effective for improvement of male pronucleus formation and further embryonic development of sperm-injected oocytes in pigs,
Theriogenology, Vol.85, No.4, 703-708, 2016.
(DOI: 10.1016/j.theriogenology.2015.10.011,   PubMed: 26559470)
25. Morita Yasuhiro, Taniguchi Masayasu, Fuminori Tanihara, Ito Aya, Namula Zhao, DO Thi Kim Lanh, Takagi Mitsuhiro, Tatsuya Takemoto and Takeshige Otoi :
The optimal period of Ca-EDTA treatment for parthenogenetic activation of porcine oocytes during maturation culture,
The Journal of Veterinary Medical Science, 2016.
(DOI: 10.1292/jvms.15-0658,   PubMed: 26947170)
26. Tetsushi Ono, Asako Takaoka, Yasuhiro Morita, Lanh Do, Fuminori Tanihara, Masayasu Taniguchi and Takeshige Otoi :
Effects of dibutyryl cyclic adenosine monophosphate and human chorionic gonadotropin on the formation of antral follicle-like structures by bovine cumulus-oocyte complexes.,
Acta Veterinaria Hungarica, Vol.63, No.4, 485-498, 2015.
(DOI: 10.1556/004.2015.045,   PubMed: 26599095,   Elsevier: Scopus)
27. L T. K. Do, Y Shibata, M Taniguchi, M Nii, T V. Nguyen, Fuminori Tanihara, M Takagi and Takeshige Otoi :
Melatonin Supplementation During In Vitro Maturation and Development Supports the Development of Porcine Embryos.,
Reproduction in Domestic Animals = Zuchthygiene, Vol.50, No.6, 1054-1058, 2015.
(DOI: 10.1111/rda.12607,   PubMed: 26392209,   Elsevier: Scopus)
28. Yasuhiro Morita, Ni Wayan Kurniani Karja, Lanh Thi Kim Do, Fuminori Tanihara, Masayasu Taniguchi and Takeshige Otoi :
Formation of an Antral Follicle-Like Structure by Bovine Cumulus-Oocyte Complexes Embedded with Fragmin/Protamine Microparticles.,
Animal Biotechnology, Vol.26, No.4, 273-275, 2015.
(DOI: 10.1080/10495398.2015.1015681,   PubMed: 26158458,   Elsevier: Scopus)
29. Megumi Shimazaki, Rentsenkhand Sambuu, Yoko Sato, Kim Lanh Thi Do, Fuminori Tanihara, Masayasu Taniguchi and Takeshige Otoi :
EFFECTS OF ORVUS ES PASTE ON THE MOTILITY AND VIABILITY OF YAK (BOS GRUNNIENS) EPIDIDYMAL AND EJACULATED SPERMATOZOA AFTER FREEZING AND THAWING.,
Cryo Letters, Vol.36, No.4, 264-269, 2015.
(PubMed: 26576001,   Elsevier: Scopus)
30. Tomohiro Isobe, Yoshihisa Ikebata, Lanh Thi Kim Do, Fuminori Tanihara, Masayasu Taniguchi and Takeshige Otoi :
In vitro development of OPU-derived bovine embryos cultured either individually or in groups with the silk protein sericin and the viability of frozen-thawed embryos after transfer.,
Animal Science Journal, Vol.86, No.7, 661-665, 2014.
(DOI: 10.1111/asj.12341,   PubMed: 25488699)
31. Manita Wittayarat, Akira Fujiwara, Kaywalee Chatdarong, Mongkol Techakumphu, Yoko Sato, Fuminori Tanihara, Yasuhiro Morita, Masayasu Taniguchi and Takeshige Otoi :
Cell cycle analysis and interspecies nuclear transfer of cat cells treated with chemical inhibitors.,
Acta Veterinaria Hungarica, Vol.62, No.2, 233-242, 2014.
(DOI: 10.1556/AVet.2013.050,   PubMed: 24334073,   Elsevier: Scopus)
32. Tamás Somfai, Koji Yoshioka, Fuminori Tanihara, Hiroyuki Kaneko, Junko Noguchi, Naomi Kashiwazaki, Takashi Nagai and Kazuhiro Kikuchi :
Generation of live piglets from cryopreserved oocytes for the first time using a defined system for in vitro embryo production.,
PLoS ONE, Vol.9, No.5, e97731, 2014.
(DOI: 10.1371/journal.pone.0097731,   PubMed: 24844283,   Elsevier: Scopus)
33. Hiroyuki Kaneko, Kazuhiro Kikuchi, Fuminori Tanihara, Junko Noguchi, Michiko Nakai, Junya Ito and Naomi Kashiwazaki :
Normal reproductive development of pigs produced using sperm retrieved from immature testicular tissue cryopreserved and grafted into nude mice.,
Theriogenology, Vol.82, No.2, 325-331, 2014.
(DOI: 10.1016/j.theriogenology.2014.04.012,   PubMed: 24835638)
34. Zhao Namula, Risa Kodama, Fuminori Tanihara, Yasuhiro Morita, Yoko Sato, Manita Wittayarat, Masayasu Taniguchi and Takeshige Otoi :
Effects of skim-milk supplementation on the quality and penetrating ability of boar semen after long-term preservation at 15 °C.,
Acta Veterinaria Hungarica, Vol.62, No.1, 106-116, 2014.
(DOI: 10.1556/AVet.2013.046,   PubMed: 24334075,   Elsevier: Scopus)
35. Fuminori Tanihara, Michiko Nakai, Nguyen Thi Men, Noriko Kato, Hiroyuki Kaneko, Junko Noguchi, Takeshige Otoi and Kazuhiro Kikuchi :
Roles of the zona pellucida and functional exposure of the sperm-egg fusion factor 'IZUMO' during in vitro fertilization in pigs.,
Animal Science Journal, Vol.85, No.4, 395-404, 2014.
(DOI: 10.1111/asj.12164,   PubMed: 24450993)
36. Fuminori Tanihara, Yukine Kaedei, Zhao Namula, Vien Viet Luu, Yoko Sato, Manita Wittayarat, Masayasu Taniguchi and Takeshige Otoi :
Comparison of activation ability between feline and bovine oocytes.,
Acta Veterinaria Hungarica, Vol.61, No.4, 491-494, 2013.
(DOI: 10.1556/AVet.2013.032,   PubMed: 23974933,   Elsevier: Scopus)
37. Thi Nguyen Men, Kazuhiro Kikuchi, Michiko Nakai, Atsunori Fukuda, Fuminori Tanihara, Junko Noguchi, Hiroyuki Kaneko, Viet Nguyen Linh, Xuan Bui Nguyen, Takashi Nagai and Atsushi Tajima :
Effect of trehalose on DNA integrity of freeze-dried boar sperm, fertilization, and embryo development after intracytoplasmic sperm injection.,
Theriogenology, Vol.80, No.9, 1033-1044, 2013.
(DOI: 10.1016/j.theriogenology.2013.08.001,   PubMed: 24041826)
38. István Egerszegi, Tamás Somfai, Michiko Nakai, Fuminori Tanihara, Junko Noguchi, Hiroyuki Kaneko, Takashi Nagai, József Rátky and Kazuhiro Kikuchi :
Comparison of cytoskeletal integrity, fertilization and developmental competence of oocytes vitrified before or after in vitro maturation in a porcine model.,
Cryobiology, Vol.67, No.3, 287-292, 2013.
(DOI: 10.1016/j.cryobiol.2013.08.009,   PubMed: 23993921)
39. Hiroyuki Kaneko, Michiko Nakai, Fuminori Tanihara, Junko Noguchi and Kazuhiro Kikuchi :
Improved developmental ability of porcine oocytes grown in nude mice after fusion with cytoplasmic fragments prepared by centrifugation: a model for utilization of primordial oocytes.,
Theriogenology, Vol.80, No.8, 887-892, 2013.
(DOI: 10.1016/j.theriogenology.2013.07.014,   PubMed: 23981298)
40. Nguyen Linh Viet, Kazuhiro Kikuchi, Michiko Nakai, Fuminori Tanihara, Junko Noguchi, Hiroyuki Kaneko, Quang Thanh Dang-Nguyen, Thi Nguyen Men, Nguyen Hanh Van, Tamas Somfai, Xuan Bui Nguyen, Takashi Nagai and Noboru Manabe :
Fertilization ability of porcine oocytes reconstructed from ooplasmic fragments produced and characterized after serial centrifugations.,
The Journal of Reproduction and Development, Vol.59, No.6, 549-556, 2013.
(DOI: 10.1262/jrd.2013-042,   PubMed: 23965685,   Elsevier: Scopus)
41. Hiroyuki Kaneko, Kazuhiro Kikuchi, Michiko Nakai, Tamas Somfai, Junko Noguchi, Fuminori Tanihara, Junya Ito and Naomi Kashiwazaki :
Generation of live piglets for the first time using sperm retrieved from immature testicular tissue cryopreserved and grafted into nude mice.,
PLoS ONE, Vol.8, No.7, e70989, 2013.
(DOI: 10.1371/journal.pone.0070989,   PubMed: 23923039,   Elsevier: Scopus)
42. Fuminori Tanihara, Michiko Nakai, Hiroyuki Kaneko, Junko Noguchi, Takeshige Otoi and Kazuhiro Kikuchi :
Evaluation of zona pellucida function for sperm penetration during in vitro fertilization in pigs.,
The Journal of Reproduction and Development, Vol.59, No.4, 385-392, 2013.
(DOI: 10.1262/jrd.2013-021,   PubMed: 23666494,   Elsevier: Scopus)
43. Tamás Somfai, Michiko Nakai, Fuminori Tanihara, Junko Noguchi, Hiroyuki Kaneko, Naomi Kashiwazaki, István Egerszegi, Takashi Nagai and Kazuhiro Kikuchi :
Comparison of ethylene glycol and propylene glycol for the vitrification of immature porcine oocytes.,
The Journal of Reproduction and Development, Vol.59, No.4, 378-384, 2013.
(DOI: 10.1262/jrd.2013-015,   PubMed: 23666455,   CiNii: 10031195875,   Elsevier: Scopus)
44. Vien Viet Luu, Keisuke Hanatate, Fuminori Tanihara, Yoko Sato, Lanh Thi Kim Do, Masayasu Taniguchi and Takeshige Otoi :
The effect of relaxin supplementation of in vitro maturation medium on the development of cat oocytes obtained from ovaries stored at 4°C.,
Reproductive Biology, Vol.13, No.2, 122-126, 2013.
(DOI: 10.1016/j.repbio.2013.04.002,   PubMed: 23719116,   Elsevier: Scopus)
45. Zhao Namula, Yoko Sato, Risa Kodama, Kouta Morinaga, Viet Vien Luu, Masayasu Taniguchi, Michiko Nakai, Fuminori Tanihara, Kazuhiro Kikuchi, Takashi Nagai and Takeshige Otoi :
Motility and fertility of boar semen after liquid preservation at 5°C for more than 2 weeks.,
Animal Science Journal, Vol.84, No.8, 600-606, 2013.
(DOI: 10.1111/asj.12049,   PubMed: 23607795,   Elsevier: Scopus)
46. Hiroyuki Kaneko, Kazuhiro Kikuchi, Michiko Nakai, Fuminori Tanihara, Junko Noguchi, Michiko Noguchi, Junya Ito and Naomi Kashiwazaki :
Normal reproductive development of offspring derived by intracytoplasmic injection of porcine sperm grown in host mice.,
Theriogenology, Vol.78, No.4, 898-906, 2012.
(DOI: 10.1016/j.theriogenology.2012.04.004,   PubMed: 22626781)
47. Y Kaedei, M Naito, H Naoi, Y Sato, M Taniguchi, Fuminori Tanihara, K Kikuchi, T Nagai and Takeshige Otoi :
Effects of (-)-epigallocatechin gallate on the motility and penetrability of frozen-thawed boar spermatozoa incubated in the fertilization medium.,
Reproduction in Domestic Animals = Zuchthygiene, Vol.47, No.6, 880-886, 2012.
(DOI: 10.1111/j.1439-0531.2012.01984.x,   PubMed: 22299777,   Elsevier: Scopus)
48. Masayasu Taniguchi, Rie Arikawa, Yukine Kaedei, Fuminori Tanihara, Zhao Namula, Vien Luu Viet, Yoko Sato and Takeshige Otoi :
Effects of cryoprotectant agents and equilibration methods on developmental competence of porcine oocytes.,
Cryo Letters, Vol.32, No.5, 410-414, 2011.
(PubMed: 22020463,   Elsevier: Scopus)
49. T Terazono, Y Kaedei, Fuminori Tanihara, Z Namula, Vl Viet, M Takagi, M Inoue, Y Sato, M Taniguchi and Takeshige Otoi :
Follicle formation in the canine ovary after autografting to a peripheral site.,
Reproduction in Domestic Animals = Zuchthygiene, Vol.47, No.2, e16-21, 2011.
(DOI: 10.1111/j.1439-0531.2011.01880.x,   PubMed: 21883513,   Elsevier: Scopus)
50. T Terazono, M Inoue, Y Kaedei, Fuminori Tanihara, Z Namula, L V Viet, Y Taura, M Takagi, T Takuma and Takeshige Otoi :
Assessment of canine ovaries autografted to various body sites.,
Theriogenology, Vol.77, No.1, 131-138, 2011.
(DOI: 10.1016/j.theriogenology.2011.07.026,   PubMed: 21872320,   Elsevier: Scopus)
51. Masao Murakami, Juan Ya Dong, Tatsuyuki Suzuki, Masayasu Taniguchi, Yukine Kaedei, Yoko Sato, Fuminori Tanihara and Takeshige Otoi :
Development and subsequent cryotolerance of domestic cat embryos cultured in serum-free and serum-containing media.,
Cryobiology, Vol.63, No.3, 170-174, 2011.
(DOI: 10.1016/j.cryobiol.2011.06.002,   PubMed: 21893054,   Elsevier: Scopus)
52. V E Abakushina, Y Morita, Y Kaedei, Fuminori Tanihara, Z Namula, L V Viet and Takeshige Otoi :
Formation of an antral follicle-like structure of bovine cumulus-oocyte complexes embedded individually or in groups in collagen gels.,
Reproduction in Domestic Animals = Zuchthygiene, Vol.46, No.3, 423-427, 2010.
(DOI: 10.1111/j.1439-0531.2010.01684.x,   PubMed: 20723136,   Elsevier: Scopus)
53. Yavari Morteza, Naoi Hideaki, Kaedei Yukine, Fuminori Tanihara, Namula Zhao, Viet Luu Vien and Takeshige Otoi :
Effects of epigallocatechin- 3-gallate on the developmental competence of parthenogenetic embryos in the pig,
Italian Journal of Animal Science, Vol.9, No.4, 386-389, 2010.
(DOI: 10.4081/ijas.2010.e73)
54. Kaedei Yukine, Fujiwara Akira, Ito Aya, Fuminori Tanihara, Morita Yasuhiro, Hanatate Keisuke, Viet Luu Vien, Namula Zhao and Takeshige Otoi :
Effect of Roscovitine Pretreatment on the Meiotic Maturation of Bovine Oocytes and their Subsequent Development after Somatic Cell Nuclear Transfer,
Journal of Animal and Veterinary Advances, Vol.9, No.22, 2848-2853, 2010.
(DOI: 10.3923/javaa.2010.2848.2853,   Elsevier: Scopus)
55. Y Kaedei, A Fujiwara, Fuminori Tanihara, Z Namula, VL Viet and Takeshige Otoi :
In vitro development of cat interspecies nuclear transfer using pig's and cow's cytoplasm,
Bulletin of the Veterinary Institute in Pulawy, Vol.54, No.3, 405-408, 2010.
(Elsevier: Scopus)
56. A Fujii, Y Kaedei, Fuminori Tanihara, A Ito, K Hanatate, K Kikuchi, T Nagai and Takeshige Otoi :
In vitro maturation and development of porcine oocytes cultured in a straw or dish using a portable incubator with a CO2 chamber.,
Reproduction in Domestic Animals = Zuchthygiene, Vol.45, No.4, 619-624, 2009.
(DOI: 10.1111/j.1439-0531.2008.01316.x,   PubMed: 19144033,   Elsevier: Scopus)
57. Agung Budiyanto, Barati Farid, Kaedei Yukine, Fuminori Tanihara and Takeshige Otoi :
Meiotic Competence and DNA Damage of Porcine Oocytes from Ovaries Exposed to an Elevated Temperature,
Journal of Animal and Veterinary Advances, Vol.7, No.10, 1179-1183, 2008.
(Elsevier: Scopus)

Proceeding of International Conference:

1. Maki Hirata, Fuminori Tanihara, Nguyen Thi Nhien, Le Anh Quynh, Hirano Takayuki and Takeshige Otoi :
Effects of CRISPR/Cas9-mediated gene targeting of porcine endogenous retrovirus on the developmental competence of porcine embryos,
The 15th Transgenic Technology Meeting (TT2019), Kobe, Apr. 2019.
2. Nguyen Thi Nhien, Fuminori Tanihara, Maki Hirata, Hirano Takayuki, Le Anh Quynh and Takeshige Otoi :
Efficiency of gene editing by electroporation of Cas9 protein (GEEP) to generate GGTA1-modified pigs,
The 15th Transgenic Technology Meeting (TT2019), Kobe, Apr. 2019.
3. Le Anh Quynh, Maki Hirata, Fuminori Tanihara, Nguyen Thi Nhien, Hirano Takayuki and Takeshige Otoi :
Effect of Cas9 protein levels on genomic mutations using the gene editing by electroporation of Cas9 protein (GEEP) system in putative zygotes,
The 15th Transgenic Technology Meeting (TT2019), Kobe, Apr. 2019.
4. Fuminori Tanihara, Maki Hirata, Nguyen Thi Nhien, Le Anh Quynh, Hirano Takayuki and Takeshige Otoi :
Assessment of PDX-1-deficient pigs generated using the CRISPR/Cas9 system introduced into porcine zygotes via electroporation,
The 15th Transgenic Technology Meeting (TT2019), Kobe, Apr. 2019.
5. Akio Kuroda, Misuzu Yamada, Yukari Tominaga, Reiko Suzuki, Motoyuki Tamaki, Yuko Akehi, Yuichi Takashi, Daisuke Otsuka, Eisuke Shimokita, Fuminori Tanihara, Kiyoe Kurahashi, Sumiko Yoshida, Itsuro Endo, Ken-ichi Aihara, Masahiro Abe, Kevin Ferreri and Munehide Matsuhisa :
Detection of pancreatic beta cell DNA in the circulation using the amplification refractory mustation system PCR,
American Diabetes Association 78th Scientific Sessions, Orlando, Jun. 2018.
6. Katsutoshi Nishio, Fuminori Tanihara, TV Nguyen, Toshiki Kunihara and Takeshige Otoi :
Effects of voltage strength on development and quality of electroporated porcine embryos.,
Transgenic Research, Vol.26, No.1, 29, Utah, USA, Oct. 2017.
7. Fuminori Tanihara, LTK Do, TV Nguyen, Toshiki Kunihara, Katsutoshi Nishio, Tatsuya Takemoto and Takeshige Otoi :
Generation of TP53-modified pigs by GEEP method: CRISPR/Cas9-mediated gene modification introduced into porcine zygotes by electroporation.,
Transgenic Research, Vol.26, No.1, 38, Utah, USA, Oct. 2017.
8. Fuminori Tanihara and Takeshige Otoi :
A simple-step generation of genetically modified pigs by genome editing by electroporation of Cas9 protein (GEEP) method.,
Forth World Congress of Reproductive Bioligy (WCRB2017), Okinawa, Sep. 2017.
9. R Kuriwaki, Y Sato, S Hagino, M Shimazaki, R Sambuu, LTK Do, Fuminori Tanihara, M Takagi, M Taniguchi and Takeshige Otoi :
Evaluation of the Leydig cell function on crossbreeding yak showing infertility.,
Forth World Congress of Reproductive Bioligy (WCRB2017), Okinawa, Sep. 2017.

Proceeding of Domestic Conference:

1. Maki Hirata, Fuminori Tanihara, Nguyen Thi Nhien, Namula Zhao and Takeshige Otoi :
ブタ体外受精卵におけるCrispr/Cas9システムを使用したゲノム編集の効率,
日本ゲノム編集学会 第3回大会, Jun. 2018.
2. Fuminori Tanihara, Maki Hirata, Nhien Thi Nguyen, Takayuki Hirano and Takeshige Otoi :
ブタ内在性レトロウイルス遺伝子を標的としたゲノム編集が胚発育能に及ぼす影響,
日本ゲノム編集学会第3回大会, Jun. 2018.
3. Fuminori Tanihara :
エレクトロポレーションによるブタ胚へのCRISPR/Cas9 システムの導入とゲノム編集ブタの作製,
第40回日本分子生物学会年会, Dec. 2017.

Et cetera, Workshop:

1. Le Anh Quynh, Fuminori Tanihara, Maki Hirata, Nguyen Thi Nhien, Takayuki Hirano and Takeshige Otoi :
Concentration of CRISPR/Cas9 components effects on genetic mosaicism of cytoplasmic microinjected porcine embryos,
第6回日本先進医工学ブタ研究会, Oct. 2018.
2. Nguyen Thi Nhien, Fuminori Tanihara, Maki Hirata, Takayuki Hirano, Le Anh Quynh, 新居 雅宏 and Takeshige Otoi :
Hypothermic storage of porcine zygotes in serum supplemented with chlorogenic acid,
第6回日本先進医工学ブタ研究会, Oct. 2018.
3. Maki Hirata, Fuminori Tanihara, Takayuki Hirano, Nhien Thi Nguyen, Quynh Anh Le, 新居 雅宏 and Takeshige Otoi :
ブタにおける受精前後でのゲノム編集が胚盤胞の変異導入効率に及ぼす影響,
第6回日本先進医工学ブタ研究会, Oct. 2018.
4. Fuminori Tanihara, Maki Hirata, Nguyen Thi Nhien, Le Anh Quynh, Takayuki Hirano, Tatsuya Takemoto, 中井 美智子, 淵本 大一郎 and Takeshige Otoi :
ゲノム編集によるTP53遺伝子改変ブタの作製と表現型の解析,
第6回日本先進医工学ブタ研究会, Oct. 2018.
5. Fuminori Tanihara, Tatsuya Takemoto, Maki Hirata, N Nguyen Thi, Toshiki Kunihara, R Nishinakamura and Takeshige Otoi :
Modification of SALL1 gene via CRISPR/Cas9-mediated gene editing introduced into porcine zygotes by electroporation,
KEY Forum: The 3rd International symposium on Stem Cell Traits and Developmental Systems, Jan. 2018.
6. Fuminori Tanihara and Takeshige Otoi :
ゲノム編集技術を用いたブタでの応用例,
第3回日本生物工学会西日本支部講演会「ゲノム編集—多様な生物種への応用研究」, Dec. 2016.
7. Fuminori Tanihara, Tatsuya Takemoto, Michiko Nakai, Eri Kitagawa, Do Thi Kim Lanh, Akira Onishi, Shunichi Suzuki, Syoichiro Senbon, Daiichiro Fuchimoto and Takeshige Otoi :
新規ゲノム編集技術を用いたPDX-1遺伝子改変ブタの作製,
第4回 日本先進医工学ブタ研究会 要旨集, 21, Oct. 2016.

Patent:

1. Tatsuya Takemoto, 橋本 昌和, Takeshige Otoi and Fuminori Tanihara : 2016-074645 (Apr. 2016), 2016-074645 (Apr. 2016).

Grants-in-Aid for Scientific Research (KAKEN Grants Database @ NII.ac.jp)

  • ゲノム編集技術を用いた糖尿病性腎症発症モデルブタの創出 (Project/Area Number: 19K16014 )
  • ゲノム編集技術を用いた免疫不全マイクロミニブタの創出 (Project/Area Number: 18K12062 )
  • Production of pigs for safe xenotransplantation by controlling infectious porcine endogenous retrovirus (PERV) (Project/Area Number: 17K19325 )
  • Production of genetically modified pigs by combined techniques of chromosome engineering and genome editing (Project/Area Number: 17H03938 )
  • Search by Researcher Number (90754680)