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Tokushima UniversityGraduate School of Biomedical Sciences医学域Medical SciencePathological SciencesDepartment of Pathology and Laboratory Medicine
Tokushima UniversityFaculty of MedicineSchool of MedicineCourse of Bioregulation and Medical OncologyPathology and Laboratory Medicine
Tokushima UniversityGraduate School of Medical SciencesMedical ScienceCourse of Bioregulation and Medical Oncology
Tokushima UniversityInstitute of Post-LED Photonics
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Research Activity

Personal Web Page

Field of Study

Pathology

Subject of Study

肝臓病理学

Book / Paper

Book:

1. Koichi Tsuneyama and Takeshi Oya :
腫瘍病理鑑別診断アトラス 肝癌 第2版 悪性リンパ腫および偽リンパ腫,
文光堂, Nov. 2020.
2. Minoru Matsumoto, Rodrigues M. Pedro, Sousa Laura, Koichi Tsuneyama, Mitsuru Matsumoto and Alves L. Nuno :
The Ins and Outs of Thymic Epithelial Cell Differentiation and Function,
Springer, Apr. 2019.
3. Hayato Baba, Ayumi Sugitani, Ryusei Takahashi, Kouki Kai, Yuki Moritoki, Kentaro Kikuchi and Koichi Tsuneyama :
Immunopathology of Bile Duct Lesions of Primary Biliary Cholangitis,
Springer Singapore, 2017.
(DOI: 10.1007/978-981-10-3500-5_6)

Academic Paper (Judged Full Paper):

1. Mayuko Shimizu, Tsuchiyama Yosuke, Morimoto Yuki, Minoru Matsumoto, Tomoko Kobayashi, Sumida Satoshi, Kakimoto Takumi, Takeshi Oya, Hirohisa Ogawa, Michiko Yamashita, Matsuda Satoru, Omagari Katsuhisa, Taira Shu and Koichi Tsuneyama :
A novel mouse model of non-alcoholic steatohepatitis suggests that liver fibrosis initiates around lipid-laden macrophages,
The American Journal of Pathology,
(Tokushima University Institutional Repository: 116411,   DOI: 10.1016/j.ajpath.2021.10.002,   PubMed: 34710382)
2. Tomoko Kobayashi, Mayuko Shimizu, Takeshi Oya, Hirohisa Ogawa, Minoru Matsumoto, Yuki Morimoto, Satoshi Sumida, Takumi Kakimoto, Michiko Yamashita, Mitsuko Sutoh, Shunji Toyohara, Ryoji Hokao, Chunmei Cheng and Koichi Tsuneyama :
Neonatal streptozotocin treatment rapidly causes different subtype of hepatocellular carcinoma without persistent hyperglycemia in 4CS mice fed on a normal diet.,
Pathology, Research and Practice, Vol.225, No.153559, 2021.
(DOI: 10.1016/j.prp.2021.153559,   PubMed: 34325313)
3. Shao-Yuan Chen, Koichi Tsuneyama, Mao-Hsiung Yen, Jiunn-Tay Lee, Jiun-Liang Chen and Shih-Ming Huang :
Hyperbaric oxygen suppressed tumor progression through the improvement of tumor hypoxia and induction of tumor apoptosis in A549-cell-transferred lung cancer.,
Scientific Reports, Vol.11, No.1, 2021.
(DOI: 10.1038/s41598-021-91454-2,   PubMed: 34103583)
4. Yuki Morimoto, Takeshi Oya, Mayuko Shimizu, Minoru Matsumoto, Hirohisa Ogawa, Tomoko Kobayashi, Satoshi Sumida, Takumi Kakimoto, Michiko Yamashita, Chunmei Cheng and Koichi Tsuneyama :
Applying Probe Electrospray Ionization Mass Spectrometry to Cytological Diagnosis: A Preliminary Study by Using Cultured Lung Cancer Cells.,
Acta Cytologica, Vol.65, No.5, 430-439, 2021.
(Tokushima University Institutional Repository: 116345,   DOI: 10.1159/000516639,   PubMed: 34098551)
5. Shin Shimoyama, Kazuhito Kawata, Kazuyoshi Ohta, Takeshi Chida, Tetsuro Suzuki, Koichi Tsuneyama, Shinji Shimoda, Nobuhito Kurono, C Patrick S Leung, Eric M Gershwin, Takafumi Suda and Yoshimasa Kobayashi :
Ursodeoxycholic acid impairs liver-infiltrating T-cell chemotaxis through IFN-γ and CX3CL1 production in primary biliary cholangitis.,
European Journal of Immunology, Vol.51, No.6, 1519-1530, 2021.
(DOI: 10.1002/eji.202048589,   PubMed: 33710617)
6. Mayuko Shimizu, Katsuhisa Omagari, Michiko Yamashita and Koichi Tsuneyama :
Development of a novel mouse model of diet-induced nonalcoholic steatohepatitis-related progressive bridging fibrosis.,
Bioscience, Biotechnology, and Biochemistry, Vol.85, No.4, 941-947, 2021.
(DOI: 10.1093/bbb/zbaa107,   PubMed: 33620426)
7. Kotaro Matsumoto, Kentaro Kikuchi, Ayako Hara, Hiromichi Tsunashima, Koichi Tsuneyama and Shinpei Doi :
Immunohistochemical detection of procalcitonin in fibrolamellar hepatocellular carcinoma.,
Clinical Journal of Gastroenterology, Vol.14, No.3, 827-830, 2021.
(DOI: 10.1007/s12328-021-01354-1,   PubMed: 33566306)
8. Hironori Tanaka, Yoshihito Saijyo, Tetsu Tomonari, Takahiro Tanaka, Tatsuya Taniguchi, Shusuke Yagi, Koichi Okamoto, Hiroshi Miyamoto, Masahiro Sogabe, Yasushi Sato, Naoki Muguruma, Koichi Tsuneyama, Masataka Sata and Tetsuji Takayama :
An Adult Case of Congenital Extrahepatic Portosystemic Shunt Successfully Treated with Balloon-occluded Retrograde Transvenous Obliteration,
Internal Medicine, Vol.60, No.12, 1839-1845, 2021.
(Tokushima University Institutional Repository: 116336,   DOI: 10.2169/internalmedicine.5914-20,   PubMed: 33456037)
9. Tomohiro Umezu, Koichi Tsuneyama, Kohsuke Kanekura, Michiyo Hayakawa, Toshihito Tanahashi, Mitsuoki Kawano, Y-H Taguchi, Hidenori Toyoda, Akihiro Tamori, Masahiko Kuroda and Yoshiki Murakami :
Comprehensive analysis of liver and blood miRNA in precancerous conditions.,
Scientific Reports, Vol.10, No.1, 2020.
(DOI: 10.1038/s41598-020-78500-1,   PubMed: 33303811)
10. Takeo Minamikawa, Mayuko Shimizu, Hiroki Takanari, Yuki Morimoto, Ryosuke Shiomi, Tanioka Hiroki, Eiji Hase, Takeshi Yasui and Koichi Tsuneyama :
Molecular imaging analysis of microvesicular and macrovesicular lipid droplets in non-alcoholic fatty liver disease by Raman microscopy.,
Scientific Reports, Vol.10, No.1, 18548, 2020.
(DOI: 10.1038/s41598-020-75604-6,   PubMed: 33122711)
11. Kondo Masateru, Yuki Izawa-Ishizawa, Mitsuhiro Goda, Hosooka Mayuko, Kagimoto Yuu, Saito Naoko, Matsuoka Rie, Yoshito Zamami, Masayuki Chuma, Kenta Yagi, Kenshi Takechi, Koichi Tsuneyama and Keisuke Ishizawa :
Preventive Effects of Quercetin against the Onset of Atherosclerosis-Related Acute Aortic Syndromes in Mice,
International Journal of Molecular Sciences, Vol.21, No.19, 2020.
(Tokushima University Institutional Repository: 115332,   DOI: 10.3390/ijms21197226,   Elsevier: Scopus)
12. Takaaki Tsunematsu, Rieko Arakaki, Hidehiko Kawai, Jan Ruppert, Koichi Tsuneyama, Naozumi Ishimaru, C William Earnshaw, Michele Pagano and Yasusei Kudo :
is required for the termination of chromosomal passenger complex activity upon mitotic exit.,
Journal of Cell Science, Vol.133, No.18, 2020.
(Tokushima University Institutional Repository: 115422,   DOI: 10.1242/jcs.251314,   PubMed: 32934012,   Elsevier: Scopus)
13. Makoto Kurano, Kazuhisa Tsukamoto, Masumi Hara, Koichi Tsuneyama, Takako Nishikawa, Hitoshi Ikeda and Yutaka Yatomi :
Modulation of sphingosine 1-phosphate by hepatobiliary cholesterol handling.,
The FASEB journal, Vol.34, No.11, 14655-14670, 2020.
(DOI: 10.1096/fj.202001397R,   PubMed: 32918529,   Elsevier: Scopus)
14. 高松 直子, Yusuke Osaki, Hiroki Yamazaki, Kazutaka Kuroda, Hirohisa Ogawa, Hisanori Uehara, Koichi Tsuneyama, Hiroyuki Nodera and Yuishin Izumi :
A case of led to diagnosis of malignancy by brachial plexus ultrasonography,
Neurosonology, Vol.33, No.2, 36-40, 2020.
(DOI: 10.2301/neurosonology.33.36,   CiNii: 130007908511)
15. Hiroyasu Akatsu, Toshie Manabe, Yoshihiro Kawade, Hajime Tanaka, Takayoshi Kanematsu, Kazuyuki Arakawa, Yoshiyuki Masaki, Chie Hishida, Takeshi Kanesaka, Norihiro Ogawa, Yoshio Hashizume, Koichi Tsuneyama, Hirotaka Ohara, Mitsuo Maruyama and Takayuki Yamamoto :
Iron deposition in autopsied liver specimens from older patients receiving intravenous iron infusion.,
PLoS ONE, Vol.15, No.8, e0237104, 2020.
(DOI: 10.1371/journal.pone.0237104,   PubMed: 32750083)
16. Mengling Li, Chengai Wu, Sualeh Jibran Muhammad, Dan Yan, Koichi Tsuneyama, Hideki Hatta, Zheng-Guo Cui and Hidekuni Inadera :
Melatonin sensitises shikonin-induced cancer cell death mediated by oxidative stress via inhibition of the SIRT3/SOD2-AKT pathway.,
Redox Biology, Vol.36, 2020.
(Tokushima University Institutional Repository: 116249,   DOI: 10.1016/j.redox.2020.101632,   PubMed: 32863233,   Elsevier: Scopus)
17. Akemi Tsutsui, Kenichi Harada, Koichi Tsuneyama, Hiep Canh Nguyen, Midori Ando, Satoko Nakamura, Koichi Mizobuchi, Nobuyuki Baba, Tomonori Senoh, Takuya Nagano, Hiroshi Shibata, Tomoko Aoki and Koichi Takaguchi :
Histopathological analysis of autoimmune hepatitis with "acute" presentation: Differentiation from drug-induced liver injury.,
Hepatology Research, Vol.50, No.9, 1047-1061, 2020.
(DOI: 10.1111/hepr.13532,   PubMed: 32515851,   Elsevier: Scopus)
18. Masaki Imanishi, Yusuke Yamakawa, Keijo Fukushima, Raiki Ikuto, Akiko Maegawa, Yuki Izawa-Ishizawa, Yuya Horinouchi, Masateru Kondo, Masatoshi Kishuku, Mitsuhiro Goda, Yoshito Zamami, Kenshi Takechi, Masayuki Chuma, Yasumasa Ikeda, Koichiro Tsuchiya, Hiromichi Fujino, Koichi Tsuneyama and Keisuke Ishizawa :
Fibroblast-specific ERK5 deficiency changes tumor vasculature and exacerbates tumor progression in a mouse model.,
Naunyn-Schmiedeberg's Archives of Pharmacology, Vol.393, No.7, 1239-1250, 2020.
(DOI: 10.1007/s00210-020-01859-5,   PubMed: 32307577)
19. Omagari Katsuhisa, Suzuta Masako, Taniguchi Asami, Kuramoto Risa, Koyama Yuko, Suruga Kazuhito, Mayuko Shimizu and Koichi Tsuneyama :
A non-obese, diet-induced animal model of nonalcoholic steatohepatitis in Wistar/ST rats compared to Sprague-Dawley rats,
Clinical Nutrition Experimental, Vol.30, 1-14, 2020.
(DOI: 10.1016/j.yclnex.2020.03.001,   Elsevier: Scopus)
20. Atsuko Takai, Kentaro Kikuchi, Mayuko Shimizu, Koichi Tsuneyama, Yuki Moritoki, Kotaro Matsumoto, Hiromichi Tsunashima, Takeshi Onda, Noriyuki Kuniyoshi, Tomoyuki Nariyama, Sho Ohyatsu, Juri Kubota, Kozue Nagumo, Shinpei Sato, Masumi Hara and Hiroshi Miyakawa :
Fructo-oligosaccharides ameliorate steatohepatitis, visceral adiposity, and associated chronic inflammation via increased production of short-chain fatty acids in a mouse model of non-alcoholic steatohepatitis.,
BMC Gastroenterology, Vol.20, No.1, 46, 2020.
(Tokushima University Institutional Repository: 114532,   DOI: 10.1186/s12876-020-01194-2,   PubMed: 32103741,   Elsevier: Scopus)
21. Minoru Matsumoto, Koichi Tsuneyama, Junko Morimoto, Kazuyoshi Hosomichi, Mitsuru Matsumoto and Hitoshi Nishijima :
Tissue-specific autoimmunity controlled by Aire in thymic and peripheral tolerance mechanisms.,
International Immunology, Vol.32, No.2, 117-131, 2020.
(Tokushima University Institutional Repository: 114944,   DOI: 10.1093/intimm/dxz066,   PubMed: 31586207)
22. Kanehiko Suwa, Takashi Yamaguchi, Katsunori Yoshida, Miki Murata, Mayuko Shimizu, Koichi Tsuneyama, Toshihito Seki and Kazuichi Okazaki :
Smad Phospho-Isoforms for Hepatocellular Carcinoma Risk Assessment in Patients with Nonalcoholic Steatohepatitis.,
Cancers, Vol.12, No.2, 286, 2020.
(Tokushima University Institutional Repository: 115043,   DOI: 10.3390/cancers12020286,   PubMed: 31991602,   Elsevier: Scopus)
23. Shingo Oda, Nanaka Miyazaki, Koichi Tsuneyama and Tsuyoshi Yokoi :
Exacerbation of gefitinib-induced liver injury by glutathione reduction in mice.,
The Journal of Toxicological Sciences, Vol.45, No.8, 493-502, 2020.
(DOI: 10.2131/jts.45.493,   PubMed: 32741899,   Elsevier: Scopus)
24. Tsugunobu Andoh, Kazunari Suzuki, Mitsuhiro Konno, Koichi Tsuneyama and Yasushi Kuraishi :
Pharmacological Characterization of a Novel Mouse Model of Cholestatic Pruritus.,
Biological & Pharmaceutical Bulletin, Vol.43, No.7, 1111-1117, 2020.
(DOI: 10.1248/bpb.b20-00097,   PubMed: 32612073,   Elsevier: Scopus)
25. Ayumi Fukuda, Marin Sasao, Eri Asakawa, Sumire Narita, Mei Hisano, Kazuhito Suruga, Mayuko Shimizu, Koichi Tsuneyama, Kazunari Tanaka and Katsuhisa Omagari :
Dietary fat, cholesterol, and cholic acid affect the histopathologic severity of nonalcoholic steatohepatitis in Sprague-Dawley rats,
Pathology, Research and Practice, Vol.215, No.11, 152599, 2019.
(DOI: 10.1016/j.prp.2019.152599,   PubMed: 31564568,   Elsevier: Scopus)
26. Chihiro Kageyama, Takuro Igawa, Yuka Gion, Noriko Iwaki, Tetsuya Tabata, Takehiro Tanaka, Eisei Kondo, Hajime Sakai, Koichi Tsuneyama, Kazuhiro Nomoto, Hiroko Noguchi, Tadashi Yoshino, Kenji Yokota and Yasuharu Sato :
Hepatic Campylobacter jejuni infection in patients with Castleman-Kojima disease (idiopathic multicentric Castleman disease with thrombocytopenia, anasarca, fever, reticulin fibrosis, and organomegaly (TAFRO) syndrome).,
Pathology International, Vol.69, No.10, 572-579, 2019.
(DOI: 10.1111/pin.12856,   PubMed: 31631463,   Elsevier: Scopus)
27. Benedetta Beretta-Piccoli Terziroli, Giorgina Mieli-Vergani, Diego Vergani, M John Vierling, David Adams, Gianfranco Alpini, M Jesus Banales, Ulrich Beuers, Einar Björnsson, Christopher Bowlus, Marco Carbone, Olivier Chazouillères, George Dalekos, Andrea Gottardi De, Kenichi Harada, Gideon Hirschfield, Pietro Invernizzi, David Jones, Edward Krawitt, Antonio Lanzavecchia, Zhe-Xiong Lian, Xiong Ma, Michael Manns, Domenico Mavilio, Mm Eamon Quigley, Federica Sallusto, Shinji Shimoda, Mario Strazzabosco, Mark Swain, Atsushi Tanaka, Michael Trauner, Koichi Tsuneyama, Ehud Zigmond and Eric M Gershwin :
The challenges of primary biliary cholangitis: What is new and what needs to be done.,
Journal of Autoimmunity, Vol.105, 2019.
(DOI: 10.1016/j.jaut.2019.102328,   PubMed: 31548157)
28. Katsuhisa Omagari, Eri Asakawa, Marin Sasao, Sumire Narita, Mei Hisano, Ayumi Fukuda, Kazuhiro Suruga, Mayuko Shimizu and Koichi Tsuneyama :
Age-related alterations of nonalcoholic steatohepatitis in Sprague-Dawley rats fed a high-fat and high-cholesterol diet.,
Journal of Nutritional Science and Vitaminology, Vol.65, No.4, 349-356, 2019.
(DOI: 10.3177/jnsv.65.349,   PubMed: 31474685,   Elsevier: Scopus)
29. Ru Jia, Shingo Oda, Koichi Tsuneyama, Yuya Urano and Tsuyoshi Yokoi :
Establishment of a mouse model of troglitazone-induced liver injury and analysis of its hepatotoxic mechanism.,
Journal of Applied Toxicology : JAT, 2019.
(DOI: 10.1002/jat.3838,   PubMed: 31294483)
30. Fuhua Yang, Taiki Takeuchi, Koichi Tsuneyama, Tsuyoshi Yokoi and Shingo Oda :
Experimental Evidence of Liver Injury by BSEP-Inhibiting Drugs With a Bile Salt Supplementation in Rats.,
Toxicological Sciences, Vol.170, No.1, 95-108, 2019.
(DOI: 10.1093/toxsci/kfz088,   PubMed: 30985903)
31. Tetsuyuki Takahashi, Hirona Ichikawa, Yuuki Morimoto, Koichi Tsuneyama and Takao Hijikata :
Inhibition of EP2/EP4 prostanoid receptor-mediated signaling suppresses IGF-1-induced proliferation of pancreatic cancer BxPC-3 cells via upregulating γ-glutamyl cyclotransferase expression.,
Biochemical and Biophysical Research Communications, Vol.516, No.2, 388-396, 2019.
(DOI: 10.1016/j.bbrc.2019.06.054,   PubMed: 31217077)
32. Ayaka Iida, Sachi Kuranuki, Ryoko Yamamoto, Masaya Uchida, Masanori Ohta, Mayuko Shimizu, Koichi Tsuneyama, Takayuki Masaki, Masataka Seike and Tsuyoshi Nakamura :
Analysis of amino acid profiles of blood over time and biomarkers associated with non-alcoholic steatohepatitis in STAM mice.,
Experimental Animals, Vol.68, No.4, 417-428, 2019.
(DOI: 10.1538/expanim.18-0152,   PubMed: 31155606)
33. Akiko Takikawa, Isao Usui, Shiho Fujisaka, Koichi Tsuneyama, Keisuke Okabe, Takashi Nakagawa, Allah Nawaz, Tomonobu Kado, Teruo Jojima, Yoshimasa Aso, Yoshihiro Hayakawa, Kunikimi Yagi and Kazuyuki Tobe :
Macrophage-specific hypoxia-inducible factor-1α deletion suppresses the development of liver tumors in high-fat diet-fed obese and diabetic mice.,
Journal of Diabetes Investigation, Vol.10, No.6, 1411-1418, 2019.
(Tokushima University Institutional Repository: 115504,   DOI: 10.1111/jdi.13047,   PubMed: 30897274,   Elsevier: Scopus)
34. Makoto Kurano, Koichi Tsuneyama, Yuki Morimoto, Masako Nishikawa and Yutaka Yatomi :
Apolipoprotein M suppresses the phenotypes of IgA nephropathy in hyper-IgA mice.,
The FASEB journal, Vol.33, No.4, 5181-5195, 2019.
(DOI: 10.1096/fj.201801748R,   PubMed: 30629456,   Elsevier: Scopus)
35. Yuki Izawa-Ishizawa, Masaki Imanishi, Yoshito Zamami, Toya Hiroki, Nagao Tomoko, Marin Morishita, Koichi Tsuneyama, Yuya Horinouchi, Yoshitaka Kihira, Kenshi Takechi, Yasumasa Ikeda, Koichiro Tsuchiya, Masanori Yoshizumi, Toshiaki Tamaki and Keisuke Ishizawa :
Development of a novel aortic dissection mouse model and evaluation of drug efficacy using in-vivo assays and database analyses.,
Journal of Hypertension, Vol.37, No.1, 73-83, 2019.
(Tokushima University Institutional Repository: 113264,   DOI: 10.1097/HJH.0000000000001898,   PubMed: 30303488)
36. Junko Morimoto, Yumiko Nishikawa, Takumi Kakimoto, Kohei Furutani, Naoki Kihara, Minoru Matsumoto, Koichi Tsuneyama, Yuko Kozono, Haruo Kozono, Katsuto Hozumi, Kazuyoshi Hosomichi, Hitoshi Nishijima and Mitsuru Matsumoto :
Aire Controls in Trans the Production of Medullary Thymic Epithelial Cells Expressing Ly-6C/Ly-6G.,
The Journal of Immunology, Vol.201, No.11, 3244-3257, 2018.
(DOI: 10.4049/jimmunol.1800950,   PubMed: 30389776)
37. Yuki Moritoki, Koichi Tsuneyama, Yuka Nakamura, Kentaro Kikuchi, Akira Shiota, Yoshiyuki Ohsugi, Zhe-Xiong Lian, Weici Zhang, Guo-Xiang Yang, Shigeharu Ueki, Masahide Takeda, Ayumi Omokawa, Tomoo Saga, Akiko Saga, Daisuke Watanabe, Masahito Miura, Yoshiyuki Ueno, C Patrick S Leung, Atsushi Tanaka, Eric M Gershwin and Makoto Hirokawa :
Anti-drug Antibodies Against a Novel Humanized Anti-CD20 Antibody Impair Its Therapeutic Effect on Primary Biliary Cholangitis in Human CD20- and FcγR-Expressing Mice.,
Frontiers in Immunology, Vol.9, 2018.
(Tokushima University Institutional Repository: 114467,   DOI: 10.3389/fimmu.2018.02534,   PubMed: 30450101)
38. Kazuchika Nishitsuji, Syunsuke Watanabe, Jinzhong Xiao, Ryosuke Nagatomo, Hirohisa Ogawa, Takaaki Tsunematsu, Hitomi Umemoto, Yuki Morimoto, Hiroyasu Akatsu, Koichi Inoue and Koichi Tsuneyama :
Effect of coffee or coffee components on gut microbiome and short-chain fatty acids in a mouse model of metabolic syndrome.,
Scientific Reports, Vol.8, No.1, 2018.
(Tokushima University Institutional Repository: 114533,   DOI: 10.1038/s41598-018-34571-9,   PubMed: 30385796)
39. Hong-Di Ma, Zhi-Bin Zhao, Wen-Tao Ma, Qing-Zhi Liu, Cai-Yue Gao, Liang Li, Jinjun Wang, Koichi Tsuneyama, Bin Liu, Weici Zhang, Yongjian Zhou, Eric M Gershwin and Zhe-Xiong Lian :
Gut microbiota translocation promotes autoimmune cholangitis.,
Journal of Autoimmunity, Vol.95, 47-57, 2018.
(DOI: 10.1016/j.jaut.2018.09.010,   PubMed: 30340822,   Elsevier: Scopus)
40. Hirohisa Ogawa, Masahiko Azuma, Takaaki Tsunematsu, Yuuki Morimoto, Mayo Kondo, Toshifumi Tezuka, Yasuhiko Nishioka and Koichi Tsuneyama :
Neutrophils induce smooth muscle hyperplasia via neutrophil elastase-induced FGF-2 in a mouse model of asthma with mixed inflammation.,
Clinical and Experimental Allergy, Vol.48, No.12, 1715-1725, 2018.
(DOI: 10.1111/cea.13263,   PubMed: 30171733)
41. Yuya Urano, Shingo Oda, Koichi Tsuneyama and Tsuyoshi Yokoi :
Comparative hepatic transcriptome analyses revealed possible pathogenic mechanisms of fasiglifam (TAK-875)-induced acute liver injury in mice.,
Chemico-Biological Interactions, Vol.296, 185-197, 2018.
(DOI: 10.1016/j.cbi.2018.09.011,   PubMed: 30243991)
42. Katsuhisa Omagari, Ayumi Fukuda, Machiko Suga, Ayumi Ogata, Shinta Nishioka, Kazuhito Suruga, Mayuko Shimizu and Koichi Tsuneyama :
Peptides Obtained by Enzymatic Decomposition of Mackerel Prevent Nonalcoholic Steatohepatitis in Sprague-Dawley Rats fed a High-fat and High-cholesterol Diet,
OBM Hepatology and Gastroenterology, Vol.2, No.3, 2018.
(DOI: 10.21926/obm.hg.1803008)
43. Mayo Kondo, Hirokazu Ogino, Hirohisa Ogawa, Tania Afroj, Yuko Toyoda, Satoshi Sakaguchi, Miki Tsuboi, Yoshimi Bando, Hisatsugu Goto, Koichi Tsuneyama and Yasuhiko Nishioka :
A case of pulmonary pleomorphic carcinoma with malignant phenotypes induced by ZEB1-associated epithelial-mesenchymal transition.,
Respiratory Medicine Case Reports, Vol.25, 119-121, 2018.
(Tokushima University Institutional Repository: 115710,   DOI: 10.1016/j.rmcr.2018.07.008,   PubMed: 30112272)
44. Ryosuke Nagatomo, Yasuki Okada, Mayuko Shimizu, Koichi Tsuneyama and Koichi Inoue :
Application of 2-Picolylamine Derivatized Ultra-high Performance Liquid Chromatography Tandem Mass Spectrometry for Determination of Short-chain Fatty Acids in Feces Samples.,
Analytical Sciences, Vol.34, No.9, 1031-1036, 2018.
(DOI: 10.2116/analsci.18SCP10,   PubMed: 30078818)
45. Kaizo Kagemoto, Koichi Okamoto, Tohshi Takaoka, Yasushi Sato, Shinji Kitamura, Tetsuo Kimura, Masahiro Sogabe, Hiroshi Miyamoto, Naoki Muguruma, Koichi Tsuneyama and Tetsuji Takayama :
Detection of aberrant crypt foci with image-enhanced endoscopy.,
Endoscopy International Open, Vol.6, No.8, E924-E933, 2018.
(Tokushima University Institutional Repository: 112032,   DOI: 10.1055/a-0621-8794,   PubMed: 30123821)
46. Cai-Yue Gao, Yuan Yao, Liang Li, Shu-Han Yang, Hui Chu, Koichi Tsuneyama, Xiao-Mei Li, M Gershwin Eric and Zhe-Xiong Lian :
Tissue resident memory CD8 T cells mediate salivary gland damage in a murine model of Sjögren's syndrome.,
Arthritis & Rheumatology, 2018.
(DOI: 10.1002/art.40676,   PubMed: 30035379)
47. Masaki Takeuchi, Shingo Oda, Koichi Tsuneyama and Tsuyoshi Yokoi :
Comprehensive analysis of serum microRNAs in hepatic sinusoidal obstruction syndrome (SOS) in rats: implication as early phase biomarkers for SOS.,
Archives of Toxicology, 2018.
(DOI: 10.1007/s00204-018-2269-x,   PubMed: 30019166)
48. Makoto Kurano, Koichi Tsuneyama, Yuki Morimoto, Tomo Shimizu, Masahiro Jona, Hidetoshi Kassai, Kazuki Nakao, Atsu Aiba and Yutaka Yatomi :
Apolipoprotein M Protects Lipopolysaccharide-Treated Mice from Death and Organ Injury.,
Thrombosis and Haemostasis, 2018.
(DOI: 10.1055/s-0038-1641750,   PubMed: 29669385)
49. Akiko Matsubara, Shingo Oda, Sho Akai, Koichi Tsuneyama and Tsuyoshi Yokoi :
Establishment of a drug-induced rhabdomyolysis mouse model by co-administration of ciprofloxacin and atorvastatin.,
Toxicology Letters, Vol.291, 184-193, 2018.
(DOI: 10.1016/j.toxlet.2018.04.016,   PubMed: 29679711)
50. Tetsuyuki Takahashi, Ulrich Deuschle, Shu Taira, Takeshi Nishida, Makoto Fujimoto, Takao Hijikata and Koichi Tsuneyama :
Tsumura-Suzuki obese diabetic mice-derived hepatic tumors closely resemble human hepatocellular carcinomas in metabolism-related genes expression and bile acid accumulation.,
Hepatology International, Vol.12, No.3, 254-261, 2018.
(Tokushima University Institutional Repository: 112472,   DOI: 10.1007/s12072-018-9860-3,   PubMed: 29651702,   Elsevier: Scopus)
51. Shota Fujimoto, Naoki Muguruma, Koichi Okamoto, Takeshi Kurihara, Yasushi Sato, Yoshihiko Miyamoto, Shinji Kitamura, Hiroshi Miyamoto, Takahiro Taguchi, Koichi Tsuneyama and Tetsuji Takayama :
A Novel Theranostic Combination of Near-infrared Fluorescence Imaging and Laser Irradiation Targeting c-KIT for Gastrointestinal Stromal Tumors.,
Theranostics, Vol.8, No.9, 2313-2328, 2018.
(Tokushima University Institutional Repository: 111436,   DOI: 10.7150/thno.22027,   PubMed: 29721082,   Elsevier: Scopus)
52. Momoko Akashi, Kazuto Tajiri, Akinori Wada, Koichi Tsuneyama, Kengo Kawai, Satoshi Yasumura, Masami Minemura, Terumi Takahara and Toshiro Sugiyama :
A Patient with Non-alcoholic Steatohepatitis Complicated by Multiple Myeloma.,
Internal Medicine, 2018.
(Tokushima University Institutional Repository: 114400,   DOI: 10.2169/internalmedicine.0092-17,   PubMed: 29491288)
53. Satoru Joshita, Kaname Yoshizawa, Takeji Umemura, Hiromasa Ohira, Atsushi Takahashi, Kenichi Harada, Canh Nguyen Hiep, Koichi Tsuneyama, Masayoshi Kage, Masayuki Nakano, Jong-Hon Kang, Kazuhiko Koike, Mikio Zeniya, Tetsuya Yasunaka, Akinobu Takaki, Takuji Torimura, Masanori Abe, Osamu Yokosuka, Atsushi Tanaka and Hajime Takikawa :
Clinical features of autoimmune hepatitis with acute presentation: a Japanese nationwide survey.,
Journal of Gastroenterology, 2018.
(DOI: 10.1007/s00535-018-1444-4,   PubMed: 29476251)
54. Shingo Oda, Masaki Takeuchi, Sho Akai, Yuji Shirai, Koichi Tsuneyama and Tsuyoshi Yokoi :
miRNA in Rat Liver Sinusoidal Endothelial Cells and Hepatocytes and Application to Circulating Biomarkers that Discern Pathogenesis of Liver Injuries.,
The American Journal of Pathology, Vol.188, No.4, 916-928, 2018.
(DOI: 10.1016/j.ajpath.2017.12.007,   PubMed: 29353062)
55. Hitoshi Nishijima, Tatsuya Kajimoto, Yoshiki Matsuoka, Yasuhiro Mouri, Junko Morimoto, Minoru Matsumoto, Hiroshi Kawano, Yasuhiko Nishioka, Hisanori Uehara, Keisuke Izumi, Koichi Tsuneyama, Il-mi Okazaki, Taku Okazaki, Kazuyoshi Hosomichi, Ayako Shiraki, Makoto Shibutani, Kunitoshi Mitsumori and Mitsuru Matsumoto :
Paradoxical development of polymyositis-like autoimmunity through augmented expression of autoimmune regulator (AIRE).,
Journal of Autoimmunity, Vol.86, 75-92, 2018.
(Tokushima University Institutional Repository: 112347,   DOI: 10.1016/j.jaut.2017.09.006,   PubMed: 28931462)
56. Kazuchika Nishitsuji, Jinzhong Xiao, Ryosuke Nagatomo, Hitomi Umemoto, Yuki Morimoto, Hiroyasu Akatsu, Koichi Inoue and Koichi Tsuneyama :
Analysis of the gut microbiome and plasma short-chain fatty acid profiles in a spontaneous mouse model of metabolic syndrome.,
Scientific Reports, Vol.7, No.1, 15876, 2017.
(Tokushima University Institutional Repository: 112394,   DOI: 10.1038/s41598-017-16189-5,   PubMed: 29158587)
57. Shohei Yamashita, Shingo Oda, Hideko Endo, Koichi Tsuneyama and Tsuyoshi Yokoi :
Neutrophil depletion protects against zomepirac-induced acute kidney injury in mice.,
Chemico-Biological Interactions, Vol.279, 102-110, 2017.
(DOI: 10.1016/j.cbi.2017.11.011,   PubMed: 29154782,   Elsevier: Scopus)
58. Yasuhiro Mouri, Yoshihiro Ueda, Tomoyoshi Yamano, Minoru Matsumoto, Koichi Tsuneyama, Tatsuo Kinashi and Mitsuru Matsumoto :
Mode of tolerance induction and requirement for Aire are governed by the cell types that express self-antigen and those that present antigen,
The Journal of Immunology, Vol.199, No.12, 3959-3971, 2017.
(DOI: 10.4049/jimmunol.1700892,   PubMed: 29101311,   Elsevier: Scopus)
59. Akemi Tsutsui, Kenichi Harada, Koichi Tsuneyama, Tomonori Senoh, Takuya Nagano, Koichi Takaguchi, Midori Ando, Satoko Nakamura, Koichi Mizobuchi and Masatoshi Kudo :
Clinicopathological Study of Autoimmune Hepatitis Cases That Were Difficult to Differentiate from Drug-Induced Liver Injury.,
Digestive Diseases, Vol.35, No.6, 506-514, 2017.
(DOI: 10.1159/000480139,   PubMed: 29040982)
60. Koichi Tsuneyama, Kazuchika Nishitsuji, Minoru Matsumoto, Tomoko Kobayashi, Yuki Morimoto, Takaaki Tsunematsu and Hirohisa Ogawa :
Animal models for analyzing metabolic syndrome-associated liver diseases.,
Pathology International, Vol.67, No.11, 539-546, 2017.
(DOI: 10.1111/pin.12600,   PubMed: 29027308)
61. R Heekyong Bae, L Deborah Hodge, Guo-Xiang Yang, C Patrick S Leung, Babu Sathi Chodisetti, C Julio Valencia, Michael Sanford, M John Fenimore, M Ziaur S Rahman, Koichi Tsuneyama, L Gary Norman, Eric M Gershwin and A Howard Young :
The interplay of type I and type II interferons in murine autoimmune cholangitis as a basis for sex-biased autoimmunity.,
Hepatology, Vol.67, No.4, 1408-1419, 2017.
(DOI: 10.1002/hep.29524,   PubMed: 28921595,   Elsevier: Scopus)
62. Hayato Baba, Makoto Kurano, Takeshi Nishida, Hideki Hatta, Ryoji Hokao and Koichi Tsuneyama :
Facilitatory effect of insulin treatment on hepatocellular carcinoma development in diabetes.,
BMC Research Notes, Vol.10, No.1, 478, 2017.
(Tokushima University Institutional Repository: 114374,   DOI: 10.1186/s13104-017-2783-6,   PubMed: 28903776)
63. Allah Nawaz, Aminuddin Aminuddin, Tomonobu Kado, Akiko Takikawa, Seiji Yamamoto, Koichi Tsuneyama, Yoshiko Igarashi, Masashi Ikutani, Yasuhiro Nishida, Yoshinori Nagai, Kiyoshi Takatsu, Johji Imura, Masakiyo Sasahara, Yukiko Okazaki, Kohjiro Ueki, Tadashi Okamura, Kumpei Tokuyama, Akira Ando, Michihiro Matsumoto, Hisashi Mori, Takashi Nakagawa, Norihiko Kobayashi, Kumiko Saeki, Isao Usui, Shiho Fujisaka and Kazuyuki Tobe :
CD206(+) M2-like macrophages regulate systemic glucose metabolism by inhibiting proliferation of adipocyte progenitors.,
Nature Communications, Vol.8, No.1, 286, 2017.
(Tokushima University Institutional Repository: 112461,   DOI: 10.1038/s41467-017-00231-1,   PubMed: 28819169)
64. Katsuhisa Omagari, Kazuhito Suruga, Akira Kyogoku, Satomi Nakamura, Ai Sakamoto, Shinta Nishioka, Mayuko Shimizu, Yuji Miyata, Koichi Tajima, Koichi Tsuneyama and Kazunari Tanaka :
A fermented mixed tea made with camellia (Camellia japonica) and third-crop green tea leaves prevents nonalcoholic steatohepatitis in Sprague-Dawley rats fed a high-fat and high-cholesterol diet.,
Hepatobiliary Surgery and Nutrition, Vol.7, No.3, 175-184, 2017.
(DOI: 10.21037/hbsn.2017.08.03,   PubMed: 30046568)
65. Kotaro Matsumoto, Mayuko Shimizu, Koichi Tsuneyama, Yuki Moritoki, Hiromichi Tsunashima, Katsuhisa Omagari, Masumi Hara, Ichiro Yasuda, Hiroshi Miyakawa and Kentaro Kikuchi :
Fructo-oligosaccharides and intestinal barrier function in a methionine-choline-deficient mouse model of nonalcoholic steatohepatitis.,
PLoS ONE, Vol.12, No.6, e0175406, 2017.
(Tokushima University Institutional Repository: 112342,   DOI: 10.1371/journal.pone.0175406,   PubMed: 28632732)
66. Mayumi Takeuchi, Kenji Matsuzaki, Koichi Tsuneyama, Masato Nishimura, Eri Takiguchi and Masafumi Harada :
Ovarian Large Cell Neuroendocrine Carcinoma Associated with Serous Carcinoma: Correlation of Pathology with MR Imaging,
Magnetic Resonance in Medical Sciences, Vol.16, No.4, 273-274, 2017.
(Tokushima University Institutional Repository: 116228,   DOI: 10.2463/mrms.ci.2016-0150,   PubMed: 28566585,   Elsevier: Scopus)
67. Seitarou Shimada, Kazuto Tajiri, Hayato Baba, Masami Minemura, Koichi Tsuneyama, Masayuki Nakano and Toshiro Sugiyama :
Peritumoral Hyperplasia in Hepatic Sclerosed Hemangioma.,
ACG Case Reports Journal, Vol.4, e61, 2017.
(DOI: 10.14309/crj.2017.61,   PubMed: 28462238)
68. Hiep Canh Nguyen, Kenichi Harada, Hirofumi Ouchi, Yasunori Sato, Koichi Tsuneyama, Masayoshi Kage, Masayuki Nakano, Kaname Yoshizawa, Atsushi Takahashi, Masanori Abe, Jong-Hon Kang, Kazuhiko Koike, Ayano Inui, Tomoo Fujisawa, Akinobu Takaki, Teruko Arinaga-Hino, Takuji Torimura, Yoshiyuki Suzuki, Keiichi Fujiwara, Mikio Zeniya, Hiromasa Ohira, Atsushi Tanaka and Hajime Takikawa :
Acute presentation of autoimmune hepatitis: a multicentre study with detailed histological evaluation in a large cohort of patients.,
Journal of Clinical Pathology, 2017.
(DOI: 10.1136/jclinpath-2016-204271,   PubMed: 28428284)
69. Masashi Ikutani, Koichi Tsuneyama, Makoto Kawaguchi, Junya Fukuoka, Fujimi Kudo, Susumu Nakae, Makoto Arita, Yoshinori Nagai, Satoshi Takaki and Kiyoshi Takatsu :
Prolonged activation of IL-5-producing ILC2 causes pulmonary arterial hypertrophy.,
JCI Insight, Vol.2, No.7, e90721, 2017.
(DOI: 10.1172/jci.insight.90721,   PubMed: 28405615)
70. Syunsuke Watanabe, Tetsuyuki Takahashi, Hirohisa Ogawa, Hisanori Uehara, Takaaki Tsunematsu, Hayato Baba, Yuki Morimoto and Koichi Tsuneyama :
Daily Coffee Intake Inhibits Pancreatic Beta Cell Damage and Nonalcoholic Steatohepatitis in a Mouse Model of Spontaneous Metabolic Syndrome, Tsumura-Suzuki Obese Diabetic Mice.,
Metabolic Syndrome and Related Disorders, Vol.15, No.4, 170-177, 2017.
(Tokushima University Institutional Repository: 113349,   DOI: 10.1089/met.2016.0114,   PubMed: 28358620)
71. Cindy Chang, Ana Lleo, Anchasa Kananurak, Fabio Grizzi, Koichi Tsuneyama, Pietro Invernizzi, L Charles Bevins and L Christopher Bowlus :
Human -Defensin 2 in Primary Sclerosing Cholangitis.,
Clinical and Translational Gastroenterology, Vol.8, No.3, e80, 2017.
(DOI: 10.1038/ctg.2017.8,   PubMed: 28300822)
72. Yuji Shirai, Shingo Oda, Sayaka Makino, Koichi Tsuneyama and Tsuyoshi Yokoi :
Establishment of a mouse model of enalapril-induced liver injury and investigation of the pathogenesis.,
Laboratory Investigation; a Journal of Technical Methods and Pathology, Vol.97, No.7, 833-842, 2017.
(DOI: 10.1038/labinvest.2017.22,   PubMed: 28263289)
73. Hong-Di Ma, Wen-Tao Ma, Qing-Zhi Liu, Zhi-Bin Zhao, Mu-Zi-Ying Liu, Koichi Tsuneyama, Jin-Ming Gao, M William Ridgway, A Aftab Ansari, Eric M Gershwin, Yun-Yun Fei and Zhe-Xiong Lian :
Chemokine receptor CXCR3 deficiency exacerbates murine autoimmune cholangitis by promoting pathogenic CD8(+) T cell activation.,
Journal of Autoimmunity, Vol.78, 19-28, 2017.
(DOI: 10.1016/j.jaut.2016.12.012,   PubMed: 28129932)
74. Mayuko Shimizu, Miki Masuzumi, Miku Kawase, Mika Sakaki, Shizuka Tamaru, Yasuo Nagata, Kazunari Tanaka, Kazuhito Suruga, Koichi Tsuneyama, Satoru Matsuda and Katsuhisa Omagari :
A diet-induced Sprague-Dawley rat model of nonalcoholic steatohepatitis-related cirrhosis.,
The Journal of Nutritional Biochemistry, Vol.40, 62-69, 2017.
(DOI: 10.1016/j.jnutbio.2016.10.007,   PubMed: 27863346)
75. Koichi Tsuneyama, Hayato Baba, Yuki Morimoto, Takaaki Tsunematsu and Hirohisa Ogawa :
Primary Biliary Cholangitis: Its Pathological Characteristics and Immunopathological Mechanisms.,
The Journal of Medical Investigation : JMI, Vol.64, No.1.2, 7-13, 2017.
(Tokushima University Institutional Repository: 111056,   DOI: 10.2152/jmi.64.7,   PubMed: 28373632)
76. Shota Morimoto, Tomoya Ishikawa, Kumoinori Hyodo, Takahiro Yamazaki, Shu Taira, Koichi Tsuneyama and Yuko Iciyanagi :
Preparation and characterization of newly developed matrix using functional γ-Fe2O3 nanoparticles for mass spectrometry in small molecules.,
Surface and Interface Analysis, Vol.48, No.11, 1127-1131, 2016.
(DOI: 10.1002/sia.6100)
77. Makoto Kawaguchi, Noboru Hara, Vladimir Bilim, Hiroshi Koike, Mituko Suzuki, Tae-Sun Kim, Nan Gao, Yu Dong, Sheng Zhang, Yuji Fujinawa, Osamu Yamamoto, Hiromi Ito, Yoshihiko Tomita, Yuchi Naruse, Akira Sakamaki, Yoko Ishii, Koichi Tsuneyama, Masaaki Inoue, Johbu Itoh, Masanori Yasuda, Nobuo Sakata, Cha-Gyun Jung, Satoshi Kanazawa, Hiroyasu Akatsu, Hiroshi Minato, Takayuki Nojima, Kiyofumi Asai and Yutaka Miura :
A diagnostic marker for superficial urothelial bladder carcinoma: lack of nuclear ATBF1 (ZFHX3) by immunohistochemistry suggests malignant progression.,
BMC Cancer, Vol.16, No.1, 805, 2016.
(Tokushima University Institutional Repository: 114356,   DOI: 10.1186/s12885-016-2845-5,   PubMed: 27756245)
78. Takeshi Nishida, Koichi Tsuneyama, Makoto Fujimoto, Kazuhiro Nomoto, Shinichi Hayashi, Shigeharu Miwa, Takahiko Nakajima, Yuko Nakanishi, Hideki Hatta and Johji Imura :
Aberrant iron metabolism might have an impact on progression of diseases in Tsumura Suzuki obese diabetes mice, a model of spontaneous metabolic syndrome.,
Pathology International, Vol.66, No.11, 622-628, 2016.
(DOI: 10.1111/pin.12466,   PubMed: 27687701)
79. Shingo Oda, Yuji Shirai, Sho Akai, Akira Nakajima, Koichi Tsuneyama and Tsuyoshi Yokoi :
Toxicological role of an acyl glucuronide metabolite in diclofenac-induced acute liver injury in mice.,
Journal of Applied Toxicology : JAT, Vol.37, No.5, 545-553, 2016.
(DOI: 10.1002/jat.3388,   PubMed: 27671914)
80. Akiko Takikawa, Arshad Mahmood, Allah Nawaz, Tomonobu Kado, Keisuke Okabe, Seiji Yamamoto, Aminuddin Aminuddin, Satoko Senda, Koichi Tsuneyama, Masashi Ikutani, Yasuharu Watanabe, Yoshiko Igarashi, Yoshinori Nagai, Kiyoshi Takatsu, Keiichi Koizumi, Johji Imura, Nobuhito Goda, Masakiyo Sasahara, Michihiro Matsumoto, Kumiko Saeki, Takashi Nakagawa, Shiho Fujisaka, Isao Usui and Kazuyuki Tobe :
HIF-1 in Myeloid Cells Promotes Adipose Tissue Remodeling Toward Insulin Resistance.,
Diabetes, Vol.65, No.12, 3649-3659, 2016.
(DOI: 10.2337/db16-0012,   PubMed: 27625023)
81. Tetsuyuki Takahashi, Takeshi Nishida, Hayato Baba, Hideki Hatta, Johji Imura, Mitsuko Sutoh, Syunji Toyohara, Ryoji Hokao, Syunsuke Watanabe, Hirohisa Ogawa, Hisanori Uehara and Koichi Tsuneyama :
Histopathological characteristics of glutamine synthetase-positive hepatic tumor lesions in a mouse model of spontaneous metabolic syndrome (TSOD mouse).,
Molecular and Clinical Oncology, Vol.5, No.2, 267-270, 2016.
(DOI: 10.3892/mco.2016.924,   PubMed: 27446562)
82. G-X Yang, Y Sun, Koichi Tsuneyama, W Zhang, P S. C. Leung, X-S He, A A. Ansari, C Bowlus, W M. Ridgway and M E. Gershwin :
Endogenous interleukin-22 protects against inflammatory bowel disease but not autoimmune cholangitis in dominant negative form of transforming growth factor beta receptor type II mice.,
Clinical and Experimental Immunology, Vol.185, No.2, 154-164, 2016.
(DOI: 10.1111/cei.12806,   PubMed: 27148790)
83. Heekyong R. Bae, Patrick S. C. Leung, Koichi Tsuneyama, Julio C. Valencia, Deborah L. Hodge, Seohyun Kim, Tim Back, Megan Karwan, Anand S. Merchant, Nobuyuki Baba, Dechun Feng, Ogyi Park, Bin Gao, Guo-Xiang Yang, M Gershwin Eric and Howard A. Young :
Chronic Expression of Interferon Gamma Leads to Murine Autoimmune Cholangitis with a Female Predominance.,
Hepatology, Vol.64, No.4, 1189-1201, 2016.
(DOI: 10.1002/hep.28641,   PubMed: 27178326,   Elsevier: Scopus)
84. Atsushi Iwamura, Katsuhito Watanabe, Sho Akai, Tsubasa Nishinosono, Koichi Tsuneyama, Shingo Oda, Toshiyuki Kume and Tsuyoshi Yokoi :
Zomepirac Acyl Glucuronide Is Responsible for Zomepirac-Induced Acute Kidney Injury in Mice.,
Drug Metabolism and Disposition, Vol.44, No.7, 888-896, 2016.
(DOI: 10.1124/dmd.116.069575,   PubMed: 27112166)
85. Akiko Takikawa, Shiho Fujisaka, Masashi Ikutani, Satoko Senda, Shinpei Hattori, Koichi Tsuneyama, Yukiko Koshimizu, Ran Inoue, Ayumi Tanaka-Hayashi, Takashi Nakagawa, Yoshinori Nagai, Kiyoshi Takatsu, Toshiyasu Sasaoka, Hisashi Mori and Kazuyuki Tobe :
Deletion of SIRT1 in myeloid cells impairs glucose metabolism with enhancing inflammatory response to adipose tissue hypoxia,
Diabetology International, Vol.7, No.1, 59-68, 2016.
(DOI: 10.1007/s13340-015-0213-3,   Elsevier: Scopus)
86. Takahiko Nakajima, Haruo Yagi, Hayato Baba, Takashi Minamisaka, Shigeharu Miwa, Shinichi Hayashi, Takeshi Nishida, Hideki Hatta, Koichi Tsuneyama and Johji Imura :
Complete Resolution of Pseudomalignant Erosion in a Reflux Gastroesophageal Polyp with Proton Pump Inhibitor.,
Case Reports in Pathology, Vol.2015, 2015.
(DOI: 10.1155/2015/657059,   PubMed: 26688768)
87. Haruka Wakae, Tomomi Higashide, Koichi Tsuneyama, Takahiro Nakamura, Kanji Takahashi and Kazuhisa Sugiyama :
Immunohistochemical Characterization of the Ectopic Epithelium Devoid of Goblet Cells From a Posttraumatic Iris Cyst Causing Mucogenic Glaucoma.,
Journal of Glaucoma, 2015.
(DOI: 10.1097/IJG.0000000000000346,   PubMed: 26550968)
88. Jing-Bo Yang, Yin-Hu Wang, Wei Yang, Fang-Ting Lu, Hong-Di Ma, Zhi-Bin Zhao, Yan-Jie Jia, Wei Tang, Koichi Tsuneyama, M William Ridgway, Eric M Gershwin and Zhe-Xiong Lian :
Successful treatment of murine autoimmune cholangitis by parabiosis: Implications for hematopoietic therapy.,
Journal of Autoimmunity, Vol.66, 108-117, 2015.
(DOI: 10.1016/j.jaut.2015.09.002,   PubMed: 26432598)
89. Hiromichi Tsunashima, Koichi Tsuneyama, Yuki Moritoki, Masumi Hara and Kentaro Kikuchi :
Accumulated myeloid-derived suppressor cells demonstrate distinct phenotypes and functions in two non-alcoholic steatohepatitis mouse models.,
Hepatobiliary Surgery and Nutrition, Vol.4, No.5, 313-319, 2015.
(DOI: 10.3978/j.issn.2304-3881.2015.04.08,   PubMed: 26605278)
90. Eita Sasaki, Azumi Iida, Shingo Oda, Koichi Tsuneyama, Tatsuki Fukami, Miki Nakajima and Tsuyoshi Yokoi :
Pathogenetic analyses of carbamazepine-induced liver injury in F344 rats focused on immune- and inflammation-related factors.,
Experimental and Toxicologic Pathology, 2015.
(DOI: 10.1016/j.etp.2015.09.004,   PubMed: 26391595)
91. Sho Akai, Yasuaki Uematsu, Koichi Tsuneyama, Shingo Oda and Tsuyoshi Yokoi :
Kupffer cell-mediated exacerbation of methimazole-induced acute liver injury in rats.,
Journal of Applied Toxicology : JAT, 2015.
(DOI: 10.1002/jat.3202,   PubMed: 26177832,   Elsevier: Scopus)
92. Zheng-Guo Cui, Ryohei Ogawa, Koichi Tsuneyama, Gen Yan, Lingling Tao, Akiko Shimomura and Hidekuni Inadera :
Insight into the molecular mechanism of heme oxygenase-1 induction by docosahexaenoic acid in U937 cells.,
Chemico-Biological Interactions, Vol.238, 180-188, 2015.
(DOI: 10.1016/j.cbi.2015.07.005,   PubMed: 26163453,   Elsevier: Scopus)
93. Koichiro Shinoda, Hirofumi Taki, Konen Obayashi, Yukio Ando, Akihiko Watanabe, Akira Komiya, Hideki Fuse, Koichi Tsuneyama and Kazuyuki Tobe :
Wild-type ATTR amyloidosis of the ureter in a 56-year-old woman with rheumatoid arthritis and Sjögren's syndrome.,
International Journal of Clinical and Experimental Pathology, Vol.8, No.7, 8624-8627, 2015.
(PubMed: 26339445)
94. Yin Fan Lam, Ka Kui Tong, Kin Ming Kwan, Koichi Tsuneyama, Shang-An Shu, Patrick S. C. Leung and Ka Hou Chu :
Gastrointestinal Immune Response to the Shrimp Allergen Tropomyosin: Histological and Immunological Analysis in an Animal Model of Shrimp Tropomyosin Hypersensitivity.,
International Archives of Allergy and Immunology, Vol.167, No.1, 29-40, 2015.
(DOI: 10.1159/000431228,   PubMed: 26112225)
95. H Tanaka, G-X Yang, T Tomiyama, Koichi Tsuneyama, W Zhang, P S. C. Leung, R L. Coppel, T Joh, S G. Nadler, A A. Ansari, C Bowlus and M E. Gershwin :
Immunological potential of cytotoxic T lymphocyte antigen 4 immunoglobulin in murine autoimmune cholangitis.,
Clinical and Experimental Immunology, Vol.180, No.3, 371-382, 2015.
(DOI: 10.1111/cei.12581,   PubMed: 25581259)
96. Kei Takahashi, Nao Nagai, Keisuke Ogura, Koichi Tsuneyama, Ikuo Saiki, Tatsuro Irimura and Yoshihiro Hayakawa :
Mammary tissue microenvironment determines T cell-dependent breast cancer-associated inflammation.,
Cancer Science, Vol.106, No.7, 867-874, 2015.
(DOI: 10.1111/cas.12685,   PubMed: 25940224)
97. Takahiko Nakajima, Toshiro Sugiyama, Hayato Baba, Hideki Hatta, Takeshi Nishida, Shigeharu Miwa, Shinichi Hayashi, Koichi Tsuneyama and Johji Imura :
Bone metastasis in gastrointestinal stromal tumors preferentially occurs in patients with original tumors in sites other than the stomach.,
International Journal of Clinical and Experimental Pathology, Vol.8, No.5, 5955-5959, 2015.
(PubMed: 26191327,   Elsevier: Scopus)
98. Akinori Wada, Aya Ito, Hirofumi Iitsuka, Koichi Tsuneyama, Takayoshi Miyazono, Jun Murakami, Naotoshi Shibahara, Hiroaki Sakurai, Ikuo Saiki, Takashi Nakayama, Osamu Yoshie, Keiichi Koizumi and Toshiro Sugiyama :
Role of chemokine CX3CL1 in progression of multiple myeloma via CX3CR1 in bone microenvironments.,
Oncology Reports, Vol.33, No.6, 2935-2939, 2015.
(DOI: 10.3892/or.2015.3941,   PubMed: 25962684)
99. Shohei Takai, Shingo Oda, Koichi Tsuneyama, Tatsuki Fukami, Miki Nakajima and Tsuyoshi Yokoi :
Establishment of a mouse model for amiodarone-induced liver injury and analyses of its hepatotoxic mechanism.,
Journal of Applied Toxicology : JAT, 2015.
(DOI: 10.1002/jat.3141,   PubMed: 25900201)
100. Azumi Iida, Eita Sasaki, Azusa Yano, Koichi Tsuneyama, Tatsuki Fukami, Miki Nakajima and Tsuyoshi Yokoi :
Carbamazepine-Induced Liver Injury Requires CYP3A-Mediated Metabolism and Glutathione Depletion in Rats.,
Drug Metabolism and Disposition, Vol.43, No.7, 958-968, 2015.
(DOI: 10.1124/dmd.115.063370,   PubMed: 25870103)
101. Shinichi Hayashi, Yoshiro Abe, Shigeki Tomita, Yuko Nakanishi, Shigeharu Miwa, Takahiko Nakajima, Kazuhiro Nomoto, Koichi Tsuneyama, Takahiro Fujimori and Johji Imura :
Primary non-gestational pure choriocarcinoma arising in the ovary: A case report and literature review.,
Oncology Letters, Vol.9, No.5, 2109-2111, 2015.
(DOI: 10.3892/ol.2015.2985,   PubMed: 26137022)
102. Fengying Gao, Satoru Yokoyama, Makoto Fujimoto, Koichi Tsuneyama, Ikuo Saiki, Yutaka Shimada and Yoshihiro Hayakawa :
Effect of keishibukuryogan on genetic and dietary obesity models.,
Evidence-Based Complementary and Alternative Medicine : eCAM, Vol.2015, 801291, 2015.
(DOI: 10.1155/2015/801291,   PubMed: 25793003)
103. Masashi Ikutani, Koichi Tsuneyama, Susumu Nakae and Kiyoshi Takatsu :
Emerging roles of IL-33 in inflammation and immune regulation,
Inflammation and Regeneration, Vol.35, No.2, 69-77, 2015.
(DOI: 10.2492/inflammregen.35.069,   CiNii: 130005063944)
104. Ji-Ye Kee, Aya Ito, Shozo Hojo, Isaya Hashimoto, Yoshiko Igarashi, Koichi Tsuneyama, Kazuhiro Tsukada, Tatsuro Irimura, Naotoshi Shibahara, Ichiro Takasaki, Akiko Inujima, Takashi Nakayama, Osamu Yoshie, Hiroaki Sakurai, Ikuo Saiki and Keiichi Koizumi :
CXCL16 suppresses liver metastasis of colorectal cancer by promoting TNF--induced apoptosis by tumor-associated macrophages.,
BMC Cancer, Vol.14, 949, 2014.
(DOI: 10.1186/1471-2407-14-949,   PubMed: 25495942)
105. H Tanaka, W Zhang, G-X Yang, Y Ando, T Tomiyama, Koichi Tsuneyama, P Leung, R L. Coppel, A A. Ansari, Z X. Lian, W M. Ridgway, T Joh and M E. Gershwin :
Successful immunotherapy of autoimmune cholangitis by adoptive transfer of forkhead box protein 3(+) regulatory T cells.,
Clinical and Experimental Immunology, Vol.178, No.2, 253-261, 2014.
(DOI: 10.1111/cei.12415,   PubMed: 25041369)
106. Hiroe Honda, Yoshinori Nagai, Takayuki Matsunaga, Naoki Okamoto, Yasuharu Watanabe, Koichi Tsuneyama, Hiroaki Hayashi, Isao Fujii, Masashi Ikutani, Yoshikatsu Hirai, Atsushi Muraguchi and Kiyoshi Takatsu :
Isoliquiritigenin is a potent inhibitor of NLRP3 inflammasome activation and diet-induced adipose tissue inflammation.,
Journal of Leukocyte Biology, Vol.96, No.6, 1087-1100, 2014.
(DOI: 10.1189/jlb.3A0114-005RR,   PubMed: 25210146)
107. Jun-Ling An, Qiao-Hong Ji, Ji-Jiang An, Shinji Masuda and Koichi Tsuneyama :
Clinicopathological analysis of CD8-positive lymphocytes in the tumor parenchyma and stroma of hepatocellular carcinoma.,
Oncology Letters, Vol.8, No.5, 2284-2290, 2014.
(DOI: 10.3892/ol.2014.2516,   PubMed: 25289108)
108. Koichi Tsuneyama, Takeshi Nishida, Hayato Baba, Shu Taira, Makoto Fujimoto, Kazuhiro Nomoto, Shinichi Hayashi, Shigeharu Miwa, Takahiko Nakajima, Mitsuko Sutoh, Emu Oda, Ryoji Hokao and Johji Imura :
Neonatal monosodium glutamate treatment causes obesity, diabetes, and macrovesicular steatohepatitis with liver nodules in DIAR mice.,
Journal of Gastroenterology and Hepatology, Vol.29, No.9, 1736-1743, 2014.
(DOI: 10.1111/jgh.12610,   PubMed: 24730643)
109. Wei Yang, Yuan Yao, Yan-Qing Yang, Fang-Ting Lu, Liang Li, Yin-Hu Wang, Takahiko Nakajima, Koichi Tsuneyama, William M. Ridgway, M Eric Gershwin and Zhe-Xiong Lian :
Differential modulation by IL-17A of Cholangitis versus Colitis in IL-2R deleted mice.,
PLoS ONE, Vol.9, No.8, e105351, 2014.
(DOI: 10.1371/journal.pone.0105351,   PubMed: 25133396)
110. Jinjun Wang, Guo-Xiang Yang, Koichi Tsuneyama, M Eric Gershwin, William M. Ridgway and Patrick S. C. Leung :
Animal models of primary biliary cirrhosis.,
Seminars in Liver Disease, Vol.34, No.3, 285-296, 2014.
(DOI: 10.1055/s-0034-1383728,   PubMed: 25057952)
111. Hayato Baba, Koichi Tsuneyama, Takeshi Nishida, Hideki Hatta, Takahiko Nakajima, Kazuhiro Nomoto, Shinichi Hayashi, Shigeharu Miwa, Yuko Nakanishi, Ryoji Hokao and Johji Imura :
Neonatal streptozotocin treatment causes type 1 diabetes and subsequent hepatocellular carcinoma in DIAR mice fed a normal diet.,
Hepatology International, Vol.8, No.3, 415-424, 2014.
(DOI: 10.1007/s12072-014-9541-9,   PubMed: 26202643)
112. Mayuko Shimizu, Miku Kawase, Miki Masuzumi, Mika Sakaki, Yasuo Nagata, Kazunari Tanaka, Kazuhito Suruga, Shizuka Tamaru, Shigeko Kato, Koichi Tsuneyama and Katsuhisa Omagari :
High-fat and high-cholesterol diet rapidly induces non-alcoholic steatohepatitis with advanced fibrosis in Sprague-Dawley rats.,
Hepatology Research, Vol.45, No.4, 458-469, 2014.
(DOI: 10.1111/hepr.12358,   PubMed: 24827559)
113. Yu Yamaura, Miki Nakajima, Naoyuki Tatsumi, Shingo Takagi, Tatsuki Fukami, Koichi Tsuneyama and Tsuyoshi Yokoi :
Changes in the expression of miRNAs at the pericentral and periportal regions of the rat liver in response to hepatocellular injury: comparison with the changes in the expression of plasma miRNAs.,
Toxicology, Vol.322, 89-98, 2014.
(DOI: 10.1016/j.tox.2014.05.008,   PubMed: 24863736)
114. Yuki Oda, Miki Nakajima, Koichi Tsuneyama, Masataka Takamiya, Yasuhiro Aoki, Tatsuki Fukami and Tsuyoshi Yokoi :
Retinoid X receptor in human liver is regulated by miR-34a.,
Biochemical Pharmacology, Vol.90, No.2, 179-187, 2014.
(DOI: 10.1016/j.bcp.2014.05.002,   PubMed: 24832862)
115. Makoto Kurano, Masumi Hara, Koichi Tsuneyama, Hideyuki Sakoda, Tomo Shimizu, Kazuhisa Tsukamoto, Hitoshi Ikeda and Yutaka Yatomi :
Induction of insulin secretion by apolipoprotein M, a carrier for sphingosine 1-phosphate.,
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, Vol.1841, No.9, 1217-1226, 2014.
(DOI: 10.1016/j.bbalip.2014.05.002,   PubMed: 24814049)
116. Kazuto Tajiri, Koichi Tsuneyama, Kengo Kawai, Yoshinari Atarashi, Masami Minemura, Shigeaki Sawada, Kazuhiro Tsukada, Johji Imura and Toshiro Sugiyama :
A case of progressing focal nodular hyperplasia and its molecular expression pattern.,
Clinical Journal of Gastroenterology, Vol.7, No.3, 271-277, 2014.
(DOI: 10.1007/s12328-014-0483-5,   PubMed: 26183749)
117. Chen-Yen Yang, Xiong Ma, Koichi Tsuneyama, Shanshan Huang, Toru Takahashi, Naga P. Chalasani, Christopher L. Bowlus, Guo-Xiang Yang, Patrick S. C. Leung, Aftab A. Ansari, Linda Wu, Ross L. Coppel and M Eric Gershwin :
IL-12/Th1 and IL-23/Th17 biliary microenvironment in primary biliary cirrhosis: implications for therapy.,
Hepatology, Vol.59, No.5, 1944-1953, 2014.
(DOI: 10.1002/hep.26979,   PubMed: 24375552)
118. Y-R Deng, K Yoshida, Q L. Jin, M Murata, T Yamaguchi, Koichi Tsuneyama, Y Moritoki, J Q. Niu, K Matsuzaki and Z-X Lian :
Reversible phospho-Smad3 signalling between tumour suppression and fibrocarcinogenesis in chronic hepatitis B infection.,
Clinical and Experimental Immunology, Vol.176, No.1, 102-111, 2014.
(DOI: 10.1111/cei.12259,   PubMed: 24372395)
119. Zheng-Guo Cui, Jin-Lan Piao, Takashi Kondo, Ryohei Ogawa, Koichi Tsuneyama, Qing-Li Zhao, Loreto B. Feril and Hidekuni Inadera :
Molecular mechanisms of hyperthermia-induced apoptosis enhanced by docosahexaenoic acid: implication for cancer therapy.,
Chemico-Biological Interactions, Vol.215, 46-53, 2014.
(DOI: 10.1016/j.cbi.2014.03.005,   PubMed: 24661947)
120. Ryo Okada, Kinzo Matsumoto, Ryohei Tsushima, Hironori Fujiwara and Koichi Tsuneyama :
Social isolation stress-induced fear memory deficit is mediated by down-regulated neuro-signaling system and Egr-1 expression in the brain.,
Neurochemical Research, Vol.39, No.5, 875-882, 2014.
(DOI: 10.1007/s11064-014-1283-5,   PubMed: 24647971)
121. Yuan Yao, Wei Yang, Yan-Qing Yang, Hong-Di Ma, Fang-Ting Lu, Liang Li, Yan-Yan Tao, Koichi Tsuneyama, Weici Zhang, Scott Friedman, M Eric Gershwin and Zhe-Xiong Lian :
Distinct from its canonical effects, deletion of IL-12p40 induces cholangitis and fibrosis in interleukin-2R-/- mice.,
Journal of Autoimmunity, Vol.51, 99-108, 2014.
(DOI: 10.1016/j.jaut.2014.02.009,   PubMed: 24651036)
122. Johji Imura, Shinichi Hayashi, Kazuhito Ichikawa, Shigeharu Miwa, Takahiko Nakajima, Kazuhiro Nomoto, Koichi Tsuneyama, Tatsuya Nogami, Hitoaki Saitoh and Takahiro Fujimori :
Malignant transformation of hyperplastic gastric polyps: An immunohistochemical and pathological study of the changes of neoplastic phenotype.,
Oncology Letters, Vol.7, No.5, 1459-1463, 2014.
(DOI: 10.3892/ol.2014.1932,   PubMed: 24765156)
123. Makoto Fujimoto, Koichi Tsuneyama, Yuko Nakanishi, Thucydides L. Salunga, Kazuhiro Nomoto, Yoshiyuki Sasaki, Seiichi Iizuka, Mitsunobu Nagata, Wataru Suzuki, Tsutomu Shimada, Masaki Aburada, Yutaka Shimada, M Eric Gershwin and Carlo Selmi :
A dietary restriction influences the progression but not the initiation of MSG-Induced nonalcoholic steatohepatitis.,
Journal of Medicinal Food, Vol.17, No.3, 374-383, 2014.
(DOI: 10.1089/jmf.2012.0029,   PubMed: 24588719)
124. Hideki Hatta, Koichi Tsuneyama, Kazuhiro Nomoto, Shinichi Hayashi, Shigeharu Miwa, Takahiko Nakajima, Takeshi Nishida, Yuko Nakanishi and Johji Imura :
A simple and rapid decalcification procedure of skeletal tissues for pathology using an ultrasonic cleaner with D-mannitol and formic acid.,
Acta Histochemica, Vol.116, No.5, 753-757, 2014.
(DOI: 10.1016/j.acthis.2014.01.006,   PubMed: 24560938,   Elsevier: Scopus)
125. J J. Wang, G-X Yang, W C. Zhang, L Lu, Koichi Tsuneyama, M Kronenberg, J L. Véla, M Lopez-Hoyos, X-S He, W M. Ridgway, P S. C. Leung and M E. Gershwin :
Escherichia coli infection induces autoimmune cholangitis and anti-mitochondrial antibodies in non-obese diabetic (NOD).B6 (Idd10/Idd18) mice.,
Clinical and Experimental Immunology, Vol.175, No.2, 192-201, 2014.
(DOI: 10.1111/cei.12224,   PubMed: 24128311)
126. Hayato Baba, Koichi Tsuneyama, Tokimasa Kumada, Keiko Aoshima and Johji Imura :
Histopathological analysis for osteomalacia and tubulopathy in itai-itai disease.,
The Journal of Toxicological Sciences, Vol.39, No.1, 91-96, 2014.
(DOI: 10.2131/jts.39.91,   PubMed: 24418713,   Elsevier: Scopus)
127. Kentaro Kikuchi, Koichi Tsuneyama, Hanae Yamada, Yusuke Kajiyama, Kotaro Matsumoto, Hiromichi Tsunashima, Risa Yamashita, Atsuko Takai, Masatsugu Negishi, Masumi Hara, Yuki Moritoki and Hiroshi Miyakawa :
Splenic lymph follicles generate immunoglobulin M-producing B cells in primary biliary cirrhosis.,
Hepatology Research, Vol.44, No.10, E253-E256, 2014.
(DOI: 10.1111/hepr.12231,   PubMed: 24033874)
128. Katsuhisa Omagari, Chisato Yoshikawa, Shin-ichi Inoue, Yuna Tanaka, Toshie Murayama, Mayuko Shimizu, Ayako Miyata, Sawako Mori, Mai Kamogawa, Eri Hirao, Shigeko Kato, Kazuhito Suruga and Koichi Tsuneyama :
Abdominal subcutaneous adipose tissue accumulation is positively correlated with hepatic steatosis in Sprague-Dawley rats,
Acta Medica Nagasakiensia, Vol.59, No.2, 47-56, 2014.
(DOI: 10.11343/amn.59.47,   CiNii: 130004879533,   Elsevier: Scopus)
129. Johji Imura, Kaori Abe, Yoshiaki Uchida, Masaharu Shibata, Kazue Tsunematsu, Motohiro Sathoh, Shigeharu Miwa, Takahiko Nakajima, Kazuhiro Nomoto, Shinichi Hayashi and Koichi Tsuneyama :
Introduction and utility of liquid-based cytology on aspiration biopsy of peripheral nodular lesions of the lung.,
Oncology Letters, Vol.7, No.3, 669-673, 2013.
(DOI: 10.3892/ol.2013.1763,   PubMed: 24520290)
130. H Tanaka, G-X Yang, N Iwakoshi, S J. Knechtle, K Kawata, Koichi Tsuneyama, P Leung, R L. Coppel, A A. Ansari, T Joh, C Bowlus and M E. Gershwin :
Anti-CD40 ligand monoclonal antibody delays the progression of murine autoimmune cholangitis.,
Clinical and Experimental Immunology, Vol.174, No.3, 364-371, 2013.
(DOI: 10.1111/cei.12193,   PubMed: 23981074)
131. Kentaro Matsuo, Eita Sasaki, Satonori Higuchi, Shohei Takai, Koichi Tsuneyama, Tatsuki Fukami, Miki Nakajima and Tsuyoshi Yokoi :
Involvement of oxidative stress and immune- and inflammation-related factors in azathioprine-induced liver injury.,
Toxicology Letters, Vol.224, No.2, 215-224, 2013.
(DOI: 10.1016/j.toxlet.2013.10.025,   PubMed: 24184165)
132. Xiao-Yu Luo, Terumi Takahara, Kengo Kawai, Masayuki Fujino, Toshiro Sugiyama, Koichi Tsuneyama, Kazuhiro Tsukada, Susumu Nakae, Liang Zhong and Xiao-Kang Li :
IFN- deficiency attenuates hepatic inflammation and fibrosis in a steatohepatitis model induced by a methionine- and choline-deficient high-fat diet.,
American Journal of Physiology, Gastrointestinal and Liver Physiology, Vol.305, No.12, G891-9, 2013.
(DOI: 10.1152/ajpgi.00193.2013,   PubMed: 24136786)
133. Kazuhito Kawata, Masanobu Tsuda, Guo-Xiang Yang, Weici Zhang, Hajime Tanaka, Koichi Tsuneyama, Patrick Leung, Xiao-Song He, Stuart Knechtle, Aftab A. Ansari, Ross L. Coppel and M Eric Gershwin :
Identification of potential cytokine pathways for therapeutic intervention in murine primary biliary cirrhosis.,
PLoS ONE, Vol.8, No.9, e74225, 2013.
(DOI: 10.1371/journal.pone.0074225,   PubMed: 24040208)
134. Eita Sasaki, Kentaro Matsuo, Azumi Iida, Koichi Tsuneyama, Tatsuki Fukami, Miki Nakajima and Tsuyoshi Yokoi :
A novel mouse model for phenytoin-induced liver injury: involvement of immune-related factors and P450-mediated metabolism.,
Toxicological Sciences, Vol.136, No.1, 250-263, 2013.
(DOI: 10.1093/toxsci/kft184,   PubMed: 23986454)
135. Yan-Ru Deng, Hong-Di Ma, Koichi Tsuneyama, Wei Yang, Yin-Hu Wang, Fang-Ting Lu, Cheng-Hai Liu, Ping Liu, Xiao-Song He, Anna Mae Diehl, M Eric Gershwin and Zhe-Xiong Lian :
STAT3-mediated attenuation of CCl4-induced mouse liver fibrosis by the protein kinase inhibitor sorafenib.,
Journal of Autoimmunity, Vol.46, 25-34, 2013.
(DOI: 10.1016/j.jaut.2013.07.008,   PubMed: 23948302)
136. Cheng-Pu Sun, Tzu-Hui Wu, Chun-Chi Chen, Ping-Yi Wu, Yao-Ming Shih, Koichi Tsuneyama and Mi-Hua Tao :
Studies of efficacy and liver toxicity related to adeno-associated virus-mediated RNA interference.,
Human Gene Therapy, Vol.24, No.8, 739-750, 2013.
(DOI: 10.1089/hum.2012.239,   PubMed: 23829557)
137. Koichi Tsuneyama, Hayato Baba, Kentaro Kikuchi, Takeshi Nishida, Kazuhiro Nomoto, Shinichi Hayashi, Shigeharu Miwa, Takahiko Nakajima, Yuko Nakanishi, Shinji Masuda, Mitsuhiro Terada, Johji Imura and Carlo Selmi :
Autoimmune features in metabolic liver disease: a single-center experience and review of the literature.,
Clinical Reviews in Allergy & Immunology, Vol.45, No.1, 143-148, 2013.
(DOI: 10.1007/s12016-013-8383-x,   PubMed: 23842720)
138. Kazuhito Kawata, Guo-Xiang Yang, Yugo Ando, Hajime Tanaka, Weici Zhang, Yoshimasa Kobayashi, Koichi Tsuneyama, Patrick S. C. Leung, Zhe-Xiong Lian, William M. Ridgway, Aftab A. Ansari, Xiao-Song He and M Eric Gershwin :
Clonality, activated antigen-specific CD8(+) T cells, and development of autoimmune cholangitis in dnTGFRII mice.,
Hepatology, Vol.58, No.3, 1094-1104, 2013.
(DOI: 10.1002/hep.26418,   PubMed: 23532950)
139. Kazuto Tajiri, Koichi Tsuneyama, Takahiro Miyazono, Kengo Kawai, Masami Minemura and Toshiro Sugiyama :
A case of primary biliary cirrhosis that progressed rapidly after treatment involving rituximab.,
Case Reports in Gastroenterology, Vol.7, No.1, 195-201, 2013.
(DOI: 10.1159/000351173,   PubMed: 23687488)
140. Mayuko Shimizu, Shigeko Kato, Koichi Tsuneyama, Sachiko Matsutake, Mai Kamogawa, Eri Hirao, Ayako Miyata, Sawako Mori, Noriaki Yamaguchi, Kazuhito Suruga and Katsuhisa Omagari :
Phycocyanin prevents hypertension and low serum adiponectin level in a rat model of metabolic syndrome.,
Nutrition Research, Vol.33, No.5, 397-405, 2013.
(DOI: 10.1016/j.nutres.2013.03.006,   PubMed: 23684441)
141. Hayato Baba, Koichi Tsuneyama, Megumi Yazaki, Kohei Nagata, Takashi Minamisaka, Tatsuhiro Tsuda, Kazuhiro Nomoto, Shinichi Hayashi, Shigeharu Miwa, Takahiko Nakajima, Yuko Nakanishi, Keiko Aoshima and Johji Imura :
The liver in itai-itai disease (chronic cadmium poisoning): pathological features and metallothionein expression.,
Modern Pathology, Vol.26, No.9, 1228-1234, 2013.
(DOI: 10.1038/modpathol.2013.62,   PubMed: 23558578)
142. S Fujisaka, I Usui, M Ikutani, A Aminuddin, A Takikawa, Koichi Tsuneyama, A Mahmood, N Goda, Y Nagai, K Takatsu and K Tobe :
Adipose tissue hypoxia induces inflammatory M1 polarity of macrophages in an HIF-1-dependent and HIF-1-independent manner in obese mice.,
Diabetologia, Vol.56, No.6, 1403-1412, 2013.
(DOI: 10.1007/s00125-013-2885-1,   PubMed: 23494472)
143. Takashi Yamaguchi, Koichi Matsuzaki, Ryosuke Inokuchi, Rinako Kawamura, Katsunori Yoshida, Miki Murata, Junichi Fujisawa, Nobuyoshi Fukushima, Michio Sata, Masayoshi Kage, Osamu Nakashima, Akihiro Tamori, Norifumi Kawada, Koichi Tsuneyama, Steven Dooley, Toshihito Seki and Kazuichi Okazaki :
Phosphorylated Smad2 and Smad3 signaling: Shifting between tumor suppression and fibro-carcinogenesis in chronic hepatitis C.,
Hepatology Research, Vol.43, No.12, 1327-1342, 2013.
(DOI: 10.1111/hepr.12082,   PubMed: 23458062)
144. Dong Han, Yasuhiko Yamamoto, Seiichi Munesue, So Motoyoshi, Hidehito Saito, Myat Thu Thu Win, Takuo Watanabe, Koichi Tsuneyama and Hiroshi Yamamoto :
Induction of receptor for advanced glycation end products by insufficient leptin action triggers pancreatic -cell failure in type 2 diabetes.,
Genes to Cells, Vol.18, No.4, 302-314, 2013.
(DOI: 10.1111/gtc.12036,   PubMed: 23410183)
145. Masanobu Tsuda, Weici Zhang, Guo-Xiang Yang, Koichi Tsuneyama, Yugo Ando, Kazuhito Kawata, Ogyi Park, C Patrick S Leung, L Ross Coppel, A Aftab Ansari, M William Ridgway, Bin Gao, Zhe-Xiong Lian, Richard Flavell, Xiao-Song He and Eric M Gershwin :
Deletion of interleukin (IL)-12p35 induces liver fibrosis in dominant-negative TGFβ receptor type II mice.,
Hepatology, Vol.57, No.2, 806-816, 2013.
(DOI: 10.1002/hep.25829,   PubMed: 22576253,   Elsevier: Scopus)
146. Amy Dhirapong, Guo-Xiang Yang, Steven Nadler, Weici Zhang, Koichi Tsuneyama, Patrick Leung, Stuart Knechtle, Aftab A. Ansari, Ross L. Coppel, Fu-Tong Liu, Xiao-Song He and M Eric Gershwin :
Therapeutic effect of cytotoxic T lymphocyte antigen 4/immunoglobulin on a murine model of primary biliary cirrhosis.,
Hepatology, Vol.57, No.2, 708-715, 2013.
(DOI: 10.1002/hep.26067,   PubMed: 22996325)
147. Shiro Watanabe and Koichi Tsuneyama :
Eicosapentaenoic acid attenuates hepatic accumulation of cholesterol esters but aggravates liver injury and inflammation in mice fed a cholate-supplemented high-fat diet.,
The Journal of Toxicological Sciences, Vol.38, No.3, 379-390, 2013.
(DOI: 10.2131/jts.38.379,   PubMed: 23665937)
148. Masahisa Arahata, Kazuto Tajiri, Kazuhiro Nomoto, Koichi Tsuneyama, Shinji Minami and Yukihiro Shimizu :
A novel type of selective immunoglobulin m deficiency in a patient with autoimmune liver cirrhosis with recurrent hepatocellular carcinoma: a case report and review of the literature.,
International Archives of Allergy and Immunology, Vol.161, No.1, 91-96, 2012.
(DOI: 10.1159/000343583,   PubMed: 23257944)
149. Chikako Inada, Xoan Le Thi, Koichi Tsuneyama, Hironori Fujiwara, Takeshi Miyata and Kinzo Matsumoto :
Endogenous acetylcholine rescues NMDA-induced long-lasting hippocampal cell damage via stimulation of muscarinic M(1) receptors: elucidation using organic hippocampal slice cultures.,
European Journal of Pharmacology, Vol.699, No.1-3, 150-159, 2012.
(DOI: 10.1016/j.ejphar.2012.11.061,   PubMed: 23220711)
150. Takeshi Nishida, Koichi Tsuneyama, Makoto Fujimoto, Kazuhiro Nomoto, Shinichi Hayashi, Shigeharu Miwa, Takahiko Nakajima, Yuko Nakanishi, Yoshiyuki Sasaki, Wataru Suzuki, Seiichi Iizuka, Mitsunobu Nagata, Tsutomu Shimada, Masaki Aburada, Yutaka Shimada and Johji Imura :
Spontaneous onset of nonalcoholic steatohepatitis and hepatocellular carcinoma in a mouse model of metabolic syndrome.,
Laboratory Investigation; a Journal of Technical Methods and Pathology, Vol.93, No.2, 230-241, 2012.
(DOI: 10.1038/labinvest.2012.155,   PubMed: 23212097)
151. Motoko Sasaki, Takashi Matsubara, Norihide Yoneda, Kazuhiro Nomoto, Koichi Tsuneyama, Yasunori Sato and Yasuni Nakanuma :
Overexpression of enhancer of zeste homolog 2 and MUC1 may be related to malignant behaviour in intraductal papillary neoplasm of the bile duct.,
Histopathology, Vol.62, No.3, 446-457, 2012.
(DOI: 10.1111/his.12016,   PubMed: 23163606)
152. Weici Zhang, Masanobu Tsuda, Guo-Xiang Yang, Koichi Tsuneyama, Xiao-Song He, A Aftab Ansari, M William Ridgway, L Ross Coppel, Zhe-Xiong Lian, C Patrick S Leung and Eric M Gershwin :
Lymphoma-like T cell infiltration in liver is associated with increased copy number of dominant negative form of TGFβ receptor II.,
PLoS ONE, Vol.7, No.11, 2012.
(DOI: 10.1371/journal.pone.0049413,   PubMed: 23145171,   Elsevier: Scopus)
153. Qi Zhao, Yimin Niu, Kinzo Matsumoto, Koichi Tsuneyama, Ken Tanaka, Takeshi Miyata and Takako Yokozawa :
Chotosan ameliorates cognitive and emotional deficits in an animal model of type 2 diabetes: possible involvement of cholinergic and VEGF/PDGF mechanisms in the brain.,
BMC Complementary and Alternative Medicine, Vol.12, 2012.
(DOI: 10.1186/1472-6882-12-188,   PubMed: 23082896,   Elsevier: Scopus)
154. Yugo Ando, Guo-Xiang Yang, Masanobu Tsuda, Kazuhito Kawata, Weici Zhang, Takahiko Nakajima, Koichi Tsuneyama, Patrick Leung, Zhe-Xiong Lian, Kazuichi Okazaki, M William Ridgway, L Gary Norman, A Aftab Ansari, Xiao-Song He, L Ross Coppel and Eric M Gershwin :
The immunobiology of colitis and cholangitis in interleukin-23p19 and interleukin-17A deleted dominant negative form of transforming growth factor beta receptor type II mice.,
Hepatology, Vol.56, No.4, 1418-1426, 2012.
(DOI: 10.1002/hep.25803,   PubMed: 22532156,   Elsevier: Scopus)
155. Kazuto Tajiri, Yukihiro Shimizu, Yoshiharu Tokimitsu, Koichi Tsuneyama and Toshiro Sugiyama :
An elderly man with syncytial giant cell hepatitis successfully treated by immunosuppressants.,
Internal Medicine, Vol.51, No.16, 2141-2144, 2012.
(DOI: 10.2169/internalmedicine.51.7870,   PubMed: 22892492,   Elsevier: Scopus)
156. Makoto Kurano, Masumi Hara, Koichi Tsuneyama, Koji Okamoto, Naoyuki Iso-O, Teruhiko Matsushima, Kazuhiko Koike and Kazuhisa Tsukamoto :
Modulation of lipid metabolism with the overexpression of NPC1L1 in mouse liver.,
Journal of Lipid Research, Vol.53, No.11, 2275-2285, 2012.
(DOI: 10.1194/jlr.M026575,   PubMed: 22891292,   Elsevier: Scopus)
157. Takahiko Nakajima, Kuniko Iihara, Junichi Fukushima, Koichi Tsuneyama, Seiko Saito, Toshirou Sugiyama and Hajime Horiuchi :
[A case of gastrointestinal stromal tumor of the stomach mimicking a primary tumor of the omentum minus due to the extramural growth].,
The Japanese Journal of Gastro-enterology, Vol.109, No.8, 1367-1371, 2012.
(PubMed: 22863960,   Elsevier: Scopus)
158. Yukitaka Yoshikawa, Taishi Miyashita, Satonori Higuchi, Koichi Tsuneyama, Shinya Endo, Tohru Tsukui, Yasuyuki Toyoda, Tatsuki Fukami, Miki Nakajima and Tsuyoshi Yokoi :
Mechanisms of the hepatoprotective effects of tamoxifen against drug-induced and chemical-induced acute liver injuries.,
Toxicology and Applied Pharmacology, Vol.264, No.1, 42-50, 2012.
(DOI: 10.1016/j.taap.2012.06.023,   PubMed: 22841776,   Elsevier: Scopus)
159. Satonori Higuchi, Azusa Yano, Shohei Takai, Koichi Tsuneyama, Tatsuki Fukami, Miki Nakajima and Tsuyoshi Yokoi :
Metabolic activation and inflammation reactions involved in carbamazepine-induced liver injury.,
Toxicological Sciences, Vol.130, No.1, 4-16, 2012.
(DOI: 10.1093/toxsci/kfs222,   PubMed: 22790970,   Elsevier: Scopus)
160. Takashi Matsubara, Yasunori Sato, Motoko Sasaki, Kenichi Harada, Kazuhiro Nomoto, Koichi Tsuneyama, Koichi Nakamura, Toshifumi Gabata, Osamu Matsui and Yasuni Nakanuma :
Immunohistochemical characteristics and malignant progression of hepatic cystic neoplasms in comparison with pancreatic counterparts.,
Human Pathology, Vol.43, No.12, 2177-2186, 2012.
(DOI: 10.1016/j.humpath.2012.03.007,   PubMed: 22705005,   Elsevier: Scopus)
161. S Shimoda, Koichi Tsuneyama, K Kikuchi, K Harada, Y Nakanuma, M Nakamura, H Ishibashi, S Hisamoto, H Niiro, C P S Leung, A A Ansari, E M Gershwin and K Akashi :
The role of natural killer (NK) and NK T cells in the loss of tolerance in murine primary biliary cirrhosis.,
Clinical and Experimental Immunology, Vol.168, No.3, 279-284, 2012.
(DOI: 10.1111/j.1365-2249.2012.04581.x,   PubMed: 22519590,   Elsevier: Scopus)
162. Yasuharu Watanabe, Tomoya Nakamura, Sho Ishikawa, Shiho Fujisaka, Isao Usui, Koichi Tsuneyama, Yoshinori Ichihara, Tsutomu Wada, Yoichiro Hirata, Takayoshi Suganami, Hirofumi Izaki, Shizuo Akira, Kensuke Miyake, Hiro-omi Kanayama, Michio Shimabukuro, Masataka Sata, Toshiyasu Sasaoka, Yoshihiro Ogawa, Kazuyuki Tobe, Kiyoshi Takatsu and Yoshinori Nagai :
The Radioprotective 105/MD-1 complex contributes to diet-induced obesity and adipose tissue inflammation.,
Diabetes, Vol.61, No.5, 1199-1209, 2012.
(DOI: 10.2337/db11-1182,   PubMed: 22396206,   Elsevier: Scopus)
163. Kazuhiro Nomoto, Takeshi Nishida, Yuko Nakanishi, Makoto Fujimoto, Ichiro Takasaki, Yoshiaki Tabuchi and Koichi Tsuneyama :
Deficiency in galectin-3 promotes hepatic injury in CDAA diet-induced nonalcoholic fatty liver disease.,
The Scientific World Journal, Vol.2012, 2012.
(DOI: 10.1100/2012/959824,   PubMed: 22593713,   Elsevier: Scopus)
164. Shu Taira, Shuichi Shimma, Issey Osaka, Daisaku Kaneko, Yuko Ichiyanagi, Ryuzo Ikeda, Yasuko Konishi-Kawamura, Shu Zhu, Koichi Tsuneyama and Katsuko Komatsu :
Mass spectrometry imaging of the capsaicin localization in the capsicum fruits,
International Journal of Biotechnology for Wellness Industries, Vol.1, No.1, 61-65, 2012.
(DOI: 10.6000/1927-3037.2012.01.01.04,   CiNii: 120004247365)
165. Qinglong Jin, Yuki Moritoki, Ana Lleo, Koichi Tsuneyama, Pietro Invernizzi, Hitoshi Moritoki, Kentaro Kikuchi, Zhe-Xiong Lian, M Gideon Hirschfield, A Aftab Ansari, L Ross Coppel, Eric M Gershwin and Junqi Niu :
Comparative analysis of portal cell infiltrates in antimitochondrial autoantibody-positive versus antimitochondrial autoantibody-negative primary biliary cirrhosis.,
Hepatology, Vol.55, No.5, 1495-1506, 2012.
(DOI: 10.1002/hep.25511,   PubMed: 22135136)
166. Hidehiro Tajima, Tetsuo Ohta, Hirohisa Kitagawa, Koichi Okamoto, Seisho Sakai, Jun Kinoshita, Isamu Makino, Hiroyuki Furukawa, Hironori Hayashi, Keishi Nakamura, Katsunobu Oyama, Masafumi Inokuchi, Hisatoshi Nakagawara, Hideto Fujita, Hiroyuki Takamura, Itasu Ninomiya, Sachio Fushida, Takashi Tani, Takashi Fujimura, Seiko Kitamura, Hiroko Ikeda and Koichi Tsuneyama :
Neoadjuvant chemotherapy with gemcitabine for pancreatic cancer increases in situ expression of the apoptosis marker M30 and stem cell marker CD44.,
Oncology Letters, Vol.3, No.6, 1186-1190, 2012.
(DOI: 10.3892/ol.2012.657,   PubMed: 22783415,   Elsevier: Scopus)
167. Makoto Fujimoto, Koichi Tsuneyama, Takako Fujimoto, Carlo Selmi, Eric M Gershwin and Yutaka Shimada :
Spirulina improves non-alcoholic steatohepatitis, visceral fat macrophage aggregation, and serum leptin in a mouse model of metabolic syndrome.,
Digestive and Liver Disease, Vol.44, No.9, 767-774, 2012.
(DOI: 10.1016/j.dld.2012.02.002,   PubMed: 22444524,   Elsevier: Scopus)
168. Toru Takahashi, Tomofumi Miura, Junichiro Nakamura, Satoshi Yamada, Tsutomu Miura, Masahiko Yanagi, Yasunobu Matsuda, Hiroyuki Usuda, Iwao Emura, Koichi Tsuneyama, Xiao-Song He and Eric M Gershwin :
Plasma cells and the chronic nonsuppurative destructive cholangitis of primary biliary cirrhosis.,
Hepatology, Vol.55, No.3, 846-855, 2012.
(DOI: 10.1002/hep.24757,   PubMed: 22031474)
169. Yu Yamaura, Miki Nakajima, Shingo Takagi, Tatsuki Fukami, Koichi Tsuneyama and Tsuyoshi Yokoi :
Plasma microRNA profiles in rat models of hepatocellular injury, cholestasis, and steatosis.,
PLoS ONE, Vol.7, No.2, 2012.
(DOI: 10.1371/journal.pone.0030250,   PubMed: 22363424,   Elsevier: Scopus)
170. K Nomoto, S Hayashi, Koichi Tsuneyama, T Hori and S Ishizawa :
Cytopathology of cervical mesonephric adenocarcinoma: a report of two cases.,
Cytopathology, Vol.24, No.2, 129-131, 2012.
(DOI: 10.1111/j.1365-2303.2012.00959.x,   PubMed: 22300170,   Elsevier: Scopus)
171. Shiro Watanabe and Koichi Tsuneyama :
Cattle bile but not bear bile or pig bile induces lipid profile changes and fatty liver injury in mice: mediation by cholic acid.,
The Journal of Toxicological Sciences, Vol.37, No.1, 105-121, 2012.
(DOI: 10.2131/jts.37.105,   PubMed: 22293415,   Elsevier: Scopus)
172. Azusa Yano, Satonori Higuchi, Koichi Tsuneyama, Tatsuki Fukami, Miki Nakajima and Tsuyoshi Yokoi :
Involvement of immune-related factors in diclofenac-induced acute liver injury in mice.,
Toxicology, Vol.293, No.1-3, 107-114, 2012.
(DOI: 10.1016/j.tox.2012.01.008,   PubMed: 22285467,   Elsevier: Scopus)
173. C Patrick S Leung, Xiang Guo Yang, Amy Dhirapong, Koichi Tsuneyama, M William Ridgway and Eric M Gershwin :
Animal models of primary biliary cirrhosis: materials and methods.,
Methods in Molecular Biology, Vol.900, 291-316, 2012.
(DOI: 10.1007/978-1-60761-720-4_14,   PubMed: 22933075,   Elsevier: Scopus)
174. Taishi Miyashita, Yasuyuki Toyoda, Koichi Tsuneyama, Tatsuki Fukami, Miki Nakajima and Tsuyoshi Yokoi :
Hepatoprotective effect of tamoxifen on steatosis and non-alcoholic steatohepatitis in mouse models.,
The Journal of Toxicological Sciences, Vol.37, No.5, 931-942, 2012.
(DOI: 10.2131/jts.37.931,   PubMed: 23038002,   Elsevier: Scopus)
175. Masashi Ikutani, Tsutomu Yanagibashi, Masaru Ogasawara, Koichi Tsuneyama, Seiji Yamamoto, Yuichi Hattori, Taku Kouro, Atsuko Itakura, Yoshinori Nagai, Satoshi Takaki and Kiyoshi Takatsu :
Identification of innate IL-5-producing cells and their role in lung eosinophil regulation and antitumor immunity.,
The Journal of Immunology, Vol.188, No.2, 703-713, 2011.
(DOI: 10.4049/jimmunol.1101270,   PubMed: 22174445,   Elsevier: Scopus)
176. Yasuyuki Toyoda, Shinya Endo, Koichi Tsuneyama, Taishi Miyashita, Azusa Yano, Tatsuki Fukami, Miki Nakajima and Tsuyoshi Yokoi :
Mechanism of exacerbative effect of progesterone on drug-induced liver injury.,
Toxicological Sciences, Vol.126, No.1, 16-27, 2011.
(DOI: 10.1093/toxsci/kfr326,   PubMed: 22157104)
177. Sumiyo Sasaki, Yoshinori Nagai, Tsutomu Yanagibashi, Yasuharu Watanabe, Masashi Ikutani, Ai Kariyone, Koichi Tsuneyama, Yoshikatsu Hirai and Kiyoshi Takatsu :
Serum soluble MD-1 levels increase with disease progression in autoimmune prone MRL(lpr/lpr) mice.,
Molecular Immunology, Vol.49, No.4, 611-620, 2011.
(DOI: 10.1016/j.molimm.2011.10.008,   PubMed: 22118968)
178. Qi Zhao, Kinzo Matsumoto, Koichi Tsuneyama, Ken Tanaka, Feng Li, Naotoshi Shibahara, Takeshi Miyata and Takako Yokozawa :
Diabetes-induced central cholinergic neuronal loss and cognitive deficit are attenuated by tacrine and a Chinese herbal prescription, kangen-karyu: elucidation in type 2 diabetes db/db mice.,
Journal of Pharmacological Sciences, Vol.117, No.4, 230-242, 2011.
(DOI: 10.1254/jphs.11115fp,   PubMed: 22083044)
179. Hiroyuki Hounoki, Koichiro Shinoda, Reina Ogawa, Hirofumi Taki, Koichi Tsuneyama and Kazuyuki Tobe :
Simultaneously developed polymyositis and autoimmune hepatitis.,
BMJ Case Reports, Vol.2011, 2011.
(DOI: 10.1136/bcr.09.2011.4763,   PubMed: 22674111)
180. Koichi Tsuneyama, Yen-Chen Chen, Makoto Fujimoto, Yoshiyuki Sasaki, Wataru Suzuki, Tsutomu Shimada, Seiichi Iizuka, Mitsunobu Nagata, Masaki Aburada and Shao-Yuan Chen :
Advantages and disadvantages of hyperbaric oxygen treatment in mice with obesity hyperlipidemia and steatohepatitis.,
The Scientific World Journal, Vol.11, 2124-2135, 2011.
(DOI: 10.1100/2011/380236,   PubMed: 22125461)
181. Masanobu Tsuda, M Yoko Ambrosini, Weici Zhang, Guo-Xiang Yang, Yugo Ando, Guanghua Rong, Koichi Tsuneyama, Kosuke Sumida, Shinji Shimoda, L Christopher Bowlus, C Patrick S Leung, Xiao-Song He, L Ross Coppel, A Aftab Ansari, Zhe-Xiong Lian and Eric M Gershwin :
Fine phenotypic and functional characterization of effector cluster of differentiation 8 positive T cells in human patients with primary biliary cirrhosis.,
Hepatology, Vol.54, No.4, 1293-1302, 2011.
(DOI: 10.1002/hep.24526,   PubMed: 21735469)
182. M Y Ambrosini, G-X Yang, W Zhang, M Tsuda, S Shu, Koichi Tsuneyama, C P S Leung, A A Ansari, L R Coppel and E M Gershwin :
The multi-hit hypothesis of primary biliary cirrhosis: polyinosinic-polycytidylic acid (poly I:C) and murine autoimmune cholangitis.,
Clinical and Experimental Immunology, Vol.166, No.1, 110-120, 2011.
(DOI: 10.1111/j.1365-2249.2011.04453.x,   PubMed: 21910728)
183. Qi Zhao, Takako Yokozawa, Koichi Tsuneyama, Ken Tanaka, Takeshi Miyata, Notoshi Shibahara and Kinzo Matsumoto :
Chotosan (Diaoteng San)-induced improvement of cognitive deficits in senescence-accelerated mouse (SAMP8) involves the amelioration of angiogenic/neurotrophic factors and neuroplasticity systems in the brain.,
Chinese Medicine, Vol.6, 2011.
(DOI: 10.1186/1749-8546-6-33,   PubMed: 21943225)
184. Ya-Hui Huang, Cheng-Chieh Fang, Koichi Tsuneyama, Ho-Yuan Chou, Wen-Yu Pan, Yao-Ming Shih, Ping-Yi Wu, Yin Chen, C Patrick S Leung, Eric M Gershwin and Mi-Hua Tao :
A murine model of hepatitis B-associated hepatocellular carcinoma generated by adeno-associated virus-mediated gene delivery.,
International Journal of Oncology, Vol.39, No.6, 1511-1519, 2011.
(DOI: 10.3892/ijo.2011.1145,   PubMed: 21805030)
185. Satonori Higuchi, Masanori Kobayashi, Azusa Yano, Koichi Tsuneyama, Tatsuki Fukami, Miki Nakajima and Tsuyoshi Yokoi :
Involvement of Th2 cytokines in the mouse model of flutamide-induced acute liver injury.,
Journal of Applied Toxicology : JAT, Vol.32, No.10, 815-822, 2011.
(DOI: 10.1002/jat.1706,   PubMed: 21735453)
186. Koichi Tsuneyama, Yuki Moritoki, Kentaro Kikuchi and Yasuni Nakanuma :
Pathological features of new animal models for primary biliary cirrhosis.,
International Journal of Hepatology, Vol.2012, 2011.
(DOI: 10.1155/2012/403954,   PubMed: 21994883)
187. N Hashimoto, S Shimoda, H Kawanaka, Koichi Tsuneyama, H Uehara, T Akahoshi, N Kinjo, A Taketomi, K Shirabe, K Akashi, A Lleo, A A Ansari, E M Gershwin and Y Maehara :
Modulation of CD4+ T cell responses following splenectomy in hepatitis C virus-related liver cirrhosis.,
Clinical and Experimental Immunology, Vol.165, No.2, 243-250, 2011.
(DOI: 10.1111/j.1365-2249.2011.04393.x,   PubMed: 21615390)
188. Yoshiyuki Sasaki, Tsutomu Shimada, Seiichi Iizuka, Wataru Suzuki, Hiroko Makihara, Ryutaro Teraoka, Koichi Tsuneyama, Ryoji Hokao and Masaki Aburada :
Effects of bezafibrate in nonalcoholic steatohepatitis model mice with monosodium glutamate-induced metabolic syndrome.,
European Journal of Pharmacology, Vol.662, No.1-3, 1-8, 2011.
(DOI: 10.1016/j.ejphar.2011.04.051,   PubMed: 21549692)
189. Yasuyuki Toyoda, Taishi Miyashita, Shinya Endo, Koichi Tsuneyama, Tatsuki Fukami, Miki Nakajima and Tsuyoshi Yokoi :
Estradiol and progesterone modulate halothane-induced liver injury in mice.,
Toxicology Letters, Vol.204, No.1, 17-24, 2011.
(DOI: 10.1016/j.toxlet.2011.03.031,   PubMed: 21501669)
190. Takao Hidaka, Akitoshi Nakashima, Toru Hasegawa, Kazuhiro Nomoto, Shin Ishizawa, Koichi Tsuneyama, Yasuo Takano and Shigeru Saito :
Ovarian squamous cell carcinoma which metastasized 8 years after cervical conization for early microinvasive cervical cancer: a case report.,
Japanese Journal of Clinical Oncology, Vol.41, No.6, 807-810, 2011.
(DOI: 10.1093/jjco/hyr041,   PubMed: 21467082)
191. Shiho Fujisaka, Isao Usui, Yukiko Kanatani, Masashi Ikutani, Ichiro Takasaki, Koichi Tsuneyama, Yoshiaki Tabuchi, Agussalim Bukhari, Yu Yamazaki, Hikari Suzuki, Satoko Senda, Aminuddin Aminuddin, Yoshinori Nagai, Kiyoshi Takatsu, Masashi Kobayashi and Kazuyuki Tobe :
Telmisartan improves insulin resistance and modulates adipose tissue macrophage polarization in high-fat-fed mice.,
Endocrinology, Vol.152, No.5, 1789-1799, 2011.
(DOI: 10.1210/en.2010-1312,   PubMed: 21427223)
192. Shinji Shimoda, Kenichi Harada, Hiroaki Niiro, Ken Shirabe, Akinobu Taketomi, Yoshihiko Maehara, Koichi Tsuneyama, Yasuni Nakanuma, Patrick Leung, A Aftab Ansari, Eric M Gershwin and Koichi Akashi :
Interaction between Toll-like receptors and natural killer cells in the destruction of bile ducts in primary biliary cirrhosis.,
Hepatology, Vol.53, No.4, 1270-1281, 2011.
(DOI: 10.1002/hep.24194,   PubMed: 21400555)
193. Si-Jie Wu, Yao-Hsu Yang, Koichi Tsuneyama, C Patrick S Leung, Petr Illarionov, Eric M Gershwin and Ya-Hui Chuang :
Innate immunity and primary biliary cirrhosis: activated invariant natural killer T cells exacerbate murine autoimmune cholangitis and fibrosis.,
Hepatology, Vol.53, No.3, 915-925, 2011.
(DOI: 10.1002/hep.24113,   PubMed: 21374662)
194. Hiroshi Oka, Hirozo Goto, Keiichi Koizumi, Shin Nakamura, Koichi Tsuneyama, Yue Zhou, Michiko Jo, Takako Fujimoto, Hiroaki Sakurai, Naotoshi Shibahara, Ikuo Saiki and Yutaka Shimada :
Effect of Hachimijiogan against Renal Dysfunction and Involvement of Hypoxia-Inducible Factor-1α in the Remnant Kidney Model.,
Evidence-Based Complementary and Alternative Medicine : eCAM, Vol.2011, 2011.
(DOI: 10.1155/2011/348686,   PubMed: 21423692)
195. Yuki Moritoki, Masanobu Tsuda, Koichi Tsuneyama, Weici Zhang, Katsunori Yoshida, Zhe-Xiong Lian, Guo-Xiang Yang, M William Ridgway, S Linda Wicker, A Aftab Ansari and Eric M Gershwin :
B cells promote hepatic inflammation, biliary cyst formation, and salivary gland inflammation in the NOD.c3c4 model of autoimmune cholangitis.,
Cellular Immunology, Vol.268, No.1, 16-23, 2011.
(DOI: 10.1016/j.cellimm.2011.01.005,   PubMed: 21349500)
196. Yasuhiko Yamamoto, Ai Harashima, Hidehito Saito, Koichi Tsuneyama, Seiichi Munesue, So Motoyoshi, Dong Han, Takuo Watanabe, Masahide Asano, Shin Takasawa, Hiroshi Okamoto, Satoshi Shimura, Tadahiro Karasawa, Hideto Yonekura and Hiroshi Yamamoto :
Septic shock is associated with receptor for advanced glycation end products ligation of LPS.,
The Journal of Immunology, Vol.186, No.5, 3248-3257, 2011.
(DOI: 10.4049/jimmunol.1002253,   PubMed: 21270403)
197. Amy Dhirapong, Ana Lleo, Guo-Xiang Yang, Koichi Tsuneyama, Robert Dunn, Marilyn Kehry, A Thomas Packard, C John Cambier, Fu-Tong Liu, Keith Lindor, L Ross Coppel, A Aftab Ansari and Eric M Gershwin :
B cell depletion therapy exacerbates murine primary biliary cirrhosis.,
Hepatology, Vol.53, No.2, 527-535, 2010.
(DOI: 10.1002/hep.24044,   PubMed: 21274873)
198. Satonori Higuchi, Masanori Kobayashi, Yukitaka Yoshikawa, Koichi Tsuneyama, Tatsuki Fukami, Miki Nakajima and Tsuyoshi Yokoi :
IL-4 mediates dicloxacillin-induced liver injury in mice.,
Toxicology Letters, Vol.200, No.3, 139-145, 2010.
(DOI: 10.1016/j.toxlet.2010.11.006,   PubMed: 21094227)
199. Kazuhiro Nomoto, Takashi Hori, Chieko Kiya, Junya Fukuoka, Akitoshi Nakashima, Takao Hidaka, Shigeru Saito, Yoshiki Mikami, Koichi Tsuneyama and Yasuo Takano :
Endometrioid adenocarcinoma of the vagina with a microglandular pattern arising from endometriosis after hysterectomy.,
Pathology International, Vol.60, No.9, 636-641, 2010.
(DOI: 10.1111/j.1440-1827.2010.02573.x,   PubMed: 20712651)
200. Qi Zhao, Takako Yokozawa, Noriko Yamabe, Koichi Tsuneyama, Xiaohan Li and Kinzo Matsumoto :
Kangen-karyu improves memory deficit caused by aging through normalization of neuro-plasticity-related signaling system and VEGF system in the brain.,
Journal of Ethnopharmacology, Vol.131, No.2, 377-385, 2010.
(DOI: 10.1016/j.jep.2010.07.016,   PubMed: 20637274)
201. Weici Zhang, Masanobu Tsuda, Guo-Xiang Yang, Koichi Tsuneyama, Guanghua Rong, M William Ridgway, A Aftab Ansari, A Richard Flavell, L Ross Coppel, Zhe-Xiong Lian and Eric M Gershwin :
Deletion of interleukin-6 in mice with the dominant negative form of transforming growth factor beta receptor II improves colitis but exacerbates autoimmune cholangitis.,
Hepatology, Vol.52, No.1, 215-222, 2010.
(DOI: 10.1002/hep.23664,   PubMed: 20578264)
202. Masanori Kobayashi, Satonori Higuchi, Katsuhiko Mizuno, Koichi Tsuneyama, Tatsuki Fukami, Miki Nakajima and Tsuyoshi Yokoi :
Interleukin-17 is involved in alpha-naphthylisothiocyanate-induced liver injury in mice.,
Toxicology, Vol.275, No.1-3, 50-57, 2010.
(DOI: 10.1016/j.tox.2010.05.011,   PubMed: 20594950)
203. Chia-Ming Chang, Chia-Hui Lo, Yao-Ming Shih, Yin Chen, Ping-Yi Wu, Koichi Tsuneyama, R Steve Roffler and Mi-Hua Tao :
Treatment of hepatocellular carcinoma with adeno-associated virus encoding interleukin-15 superagonist.,
Human Gene Therapy, Vol.21, No.5, 611-621, 2010.
(DOI: 10.1089/hum.2009.187,   PubMed: 20064014)
204. Makoto Fujimoto, Koichi Tsuneyama, Hideki Kinoshita, Hirozo Goto, Yasuo Takano, Carlo Selmi, L Carl Keen, Eric M Gershwin and Yutaka Shimada :
The traditional Japanese formula keishibukuryogan reduces liver injury and inflammation in patients with nonalcoholic fatty liver disease.,
Annals of the New York Academy of Sciences, Vol.1190, 151-158, 2010.
(DOI: 10.1111/j.1749-6632.2009.05265.x,   PubMed: 20388146)
205. Yasuni Nakanuma, Yoh Zen, Kenichi Harada, Motoko Sasaki, Akitaka Nonomura, Takeshi Uehara, Kenji Sano, Fukuo Kondo, Toshio Fukusato, Koichi Tsuneyama, Masahiro Ito, Kenichi Wakasa, Minoru Nomoto, Hiroshi Minato, Hironori Haga, Masayoshi Kage, Hirohisa Yano, Joji Haratake, Shinichi Aishima, Tomoyuki Masuda, Hajime Aoyama, Aya Miyakawa-Hayashino, Toshiharu Matsumoto, Hayato Sanefuji, Hidenori Ojima, Tse-Ching Chen, Eunsil Yu, Ji-Hun Kim, Nyun Young Park and Wilson Tsui :
Application of a new histological staging and grading system for primary biliary cirrhosis to liver biopsy specimens: Interobserver agreement.,
Pathology International, Vol.60, No.3, 167-174, 2010.
(DOI: 10.1111/j.1440-1827.2009.02500.x,   PubMed: 20403042)
206. Hideki Hatta, Koichi Tsuneyama, Takashi Kondo and Yasuo Takano :
Development of an ultrasound-emitting device for performing rapid immunostaining procedures.,
The Journal of Histochemistry and Cytochemistry, Vol.58, No.5, 421-428, 2010.
(DOI: 10.1369/jhc.2010.955096,   PubMed: 20124095)
207. Shinji Shimoda, Kenichi Harada, Hiroaki Niiro, Akinobu Taketomi, Yoshihiko Maehara, Koichi Tsuneyama, Kentaro Kikuchi, Yasuni Nakanuma, R Ian Mackay, Eric M Gershwin and Koichi Akashi :
CX3CL1 (fractalkine): a signpost for biliary inflammation in primary biliary cirrhosis.,
Hepatology, Vol.51, No.2, 567-575, 2010.
(DOI: 10.1002/hep.23318,   PubMed: 19908209)
208. Satuski Yasumura, Hideo Shojaku, Rinnosuke Wada, Yukio Watanabe, Hiroko Shojaku, Hikaru Seto, Masaya Kawano and Koichi Tsuneyama :
Usefulness of Positron Emission Tomography for management of ocular sebaceous carcinoma.,
Clinical Nuclear Medicine, Vol.35, No.2, 98-100, 2010.
(DOI: 10.1097/RLU.0b013e3181c7bea2,   PubMed: 20090456)
209. Katsuhisa Omagari, Shigeko Kato, Koichi Tsuneyama, Hideki Hatta, Miki Sato, Mizuho Hamasaki, Yukiko Sadakane, Takehiro Tashiro, Mitsue Fukuhata, Yuji Miyata, Shizuka Tamaru, Kazunari Tanaka and Masatoshi Mune :
Olive leaf extract prevents spontaneous occurrence of non-alcoholic steatohepatitis in SHR/NDmcr-cp rats.,
Pathology, Vol.42, No.1, 66-72, 2010.
(DOI: 10.3109/00313020903434389,   PubMed: 20025483)
210. Shinji Nakada, Koichi Tsuneyama, Ichiro Kato, Yoshiaki Tabuchi, Ichiro Takasaki, Yukihiro Furusawa, Hiroshi Kawaguchi, Makoto Fujimoto, Hirozo Goto, Hiroaki Hikiami, Takashi Kondo, Yasuo Takano and Yutaka Shimada :
Identification of candidate genes involved in endogenous protection mechanisms against acute pancreatitis in mice.,
Biochemical and Biophysical Research Communications, Vol.391, No.3, 1342-1347, 2009.
(DOI: 10.1016/j.bbrc.2009.12.047,   PubMed: 20026013)
211. Keiichi Koizumi, Yurika Saitoh, Takayuki Minami, Nobuhiro Takeno, Koichi Tsuneyama, Tatsuro Miyahara, Takashi Nakayama, Hiroaki Sakurai, Yasuo Takano, Miyuki Nishimura, Toshio Imai, Osamu Yoshie and Ikuo Saiki :
Role of CX3CL1/fractalkine in osteoclast differentiation and bone resorption.,
The Journal of Immunology, Vol.183, No.12, 7825-7831, 2009.
(DOI: 10.4049/jimmunol.0803627,   PubMed: 19923448)
212. Mika Ito, Akitoshi Nakashima, Takao Hidaka, Motonori Okabe, Duy Nguyen Bac, Shihomi Ina, Satoshi Yoneda, Arihiro Shiozaki, Shigeki Sumi, Koichi Tsuneyama, Toshio Nikaido and Shigeru Saito :
A role for IL-17 in induction of an inflammation at the fetomaternal interface in preterm labour.,
Journal of Reproductive Immunology, Vol.84, No.1, 75-85, 2009.
(DOI: 10.1016/j.jri.2009.09.005,   PubMed: 19969371)
213. Carlo Selmi and Koichi Tsuneyama :
Nutrition, geoepidemiology, and autoimmunity.,
Autoimmunity Reviews, Vol.9, No.5, A267-70, 2009.
(DOI: 10.1016/j.autrev.2009.12.001,   PubMed: 19969106)
214. Yuki Moritoki, Zhe-Xiong Lian, Keith Lindor, Joseph Tuscano, Koichi Tsuneyama, Weici Zhang, Yoshiyuki Ueno, Robert Dunn, Marilyn Kehry, L Ross Coppel, R Ian Mackay and Eric M Gershwin :
B-cell depletion with anti-CD20 ameliorates autoimmune cholangitis but exacerbates colitis in transforming growth factor-beta receptor II dominant negative mice.,
Hepatology, Vol.50, No.6, 1893-1903, 2009.
(DOI: 10.1002/hep.23238,   PubMed: 19877182)
215. Katsunori Yoshida, Guo-Xiang Yang, Weici Zhang, Masanobu Tsuda, Koichi Tsuneyama, Yuki Moritoki, A Aftab Ansari, Kazuichi Okazaki, Zhe-Xiong Lian, L Ross Coppel, R Ian Mackay and Eric M Gershwin :
Deletion of interleukin-12p40 suppresses autoimmune cholangitis in dominant negative transforming growth factor beta receptor type II mice.,
Hepatology, Vol.50, No.5, 1494-1500, 2009.
(DOI: 10.1002/hep.23132,   PubMed: 19676134)
216. Yu Yamazaki, Isao Usui, Yukiko Kanatani, Yuji Matsuya, Koichi Tsuneyama, Shiho Fujisaka, Agussalim Bukhari, Hikari Suzuki, Satoko Senda, Shingo Imanishi, Kazuya Hirata, Manabu Ishiki, Ryuji Hayashi, Masaharu Urakaze, Hideo Nemoto, Masashi Kobayashi and Kazuyuki Tobe :
Treatment with SRT1720, a SIRT1 activator, ameliorates fatty liver with reduced expression of lipogenic enzymes in MSG mice.,
American Journal of Physiology, Endocrinology and Metabolism, Vol.297, No.5, E1179-86, 2009.
(DOI: 10.1152/ajpendo.90997.2008,   PubMed: 19724016)
217. W Zhang, Y Moritoki, Koichi Tsuneyama, G-X Yang, Y Ilan, Z-X Lian and E M Gershwin :
Beta-glucosylceramide ameliorates liver inflammation in murine autoimmune cholangitis.,
Clinical and Experimental Immunology, Vol.157, No.3, 359-364, 2009.
(DOI: 10.1111/j.1365-2249.2009.03971.x,   PubMed: 19664143)
218. Hiroyuki Takahashi, Shigeharu Miwa, Kazuhiro Nomoto, Shinichi Hayashi, Koichi Tsuneyama and Yasuo Takano :
Peribiliary cyst of common bile duct: possible cause of refractory jaundice.,
Pathology International, Vol.59, No.9, 692-693, 2009.
(DOI: 10.1111/j.1440-1827.2009.02430.x,   PubMed: 19712142)
219. Shiho Fujisaka, Isao Usui, Agussalim Bukhari, Masashi Ikutani, Takeshi Oya, Yukiko Kanatani, Koichi Tsuneyama, Yoshinori Nagai, Kiyoshi Takatsu, Masaharu Urakaze, Masashi Kobayashi and Kazuyuki Tobe :
Regulatory mechanisms for adipose tissue M1 and M2 macrophages in diet-induced obese mice.,
Diabetes, Vol.58, No.11, 2574-2582, 2009.
(DOI: 10.2337/db08-1475,   PubMed: 19690061)
220. Yoshiyuki Sasaki, Wataru Suzuki, Tsutomu Shimada, Seiichi Iizuka, Satoko Nakamura, Mitsunobu Nagata, Makoto Fujimoto, Koichi Tsuneyama, Ryoji Hokao, Ken-Ichi Miyamoto and Masaki Aburada :
Dose dependent development of diabetes mellitus and non-alcoholic steatohepatitis in monosodium glutamate-induced obese mice.,
Life Sciences, Vol.85, No.13-14, 490-498, 2009.
(DOI: 10.1016/j.lfs.2009.07.017,   PubMed: 19683013)
221. Yukitaka Yoshikawa, Mayu Morita, Hiroko Hosomi, Koichi Tsuneyama, Tatsuki Fukami, Miki Nakajima and Tsuyoshi Yokoi :
Knockdown of superoxide dismutase 2 enhances acetaminophen-induced hepatotoxicity in rat.,
Toxicology, Vol.264, No.1-2, 89-95, 2009.
(DOI: 10.1016/j.tox.2009.07.017,   PubMed: 19647030)
222. Eisuke Kobayashi, Masanori Kobayashi, Koichi Tsuneyama, Tatsuki Fukami, Miki Nakajima and Tsuyoshi Yokoi :
Halothane-induced liver injury is mediated by interleukin-17 in mice.,
Toxicological Sciences, Vol.111, No.2, 302-310, 2009.
(DOI: 10.1093/toxsci/kfp165,   PubMed: 19633216)
223. Kazuto Tajiri, Yukihiro Shimizu, Koichi Tsuneyama and Toshiro Sugiyama :
Role of liver-infiltrating CD3+CD56+ natural killer T cells in the pathogenesis of nonalcoholic fatty liver disease.,
European Journal of Gastroenterology & Hepatology, Vol.21, No.6, 673-680, 2009.
(DOI: 10.1097/MEG.0b013e32831bc3d6,   PubMed: 19318971)
224. Mayu Morita, Sho Akai, Hiroko Hosomi, Koichi Tsuneyama, Miki Nakajima and Tsuyoshi Yokoi :
Drug-induced hepatotoxicity test using gamma-glutamylcysteine synthetase knockdown rat.,
Toxicology Letters, Vol.189, No.2, 159-165, 2009.
(DOI: 10.1016/j.toxlet.2009.05.016,   PubMed: 19481141)
225. Weici Zhang, Rahul Sharma, Shyr-Te Ju, Xiao-Song He, Yanyan Tao, Koichi Tsuneyama, Zhigang Tian, Zhe-Xiong Lian, Man Shu Fu and Eric M Gershwin :
Deficiency in regulatory T cells results in development of antimitochondrial antibodies and autoimmune cholangitis.,
Hepatology, Vol.49, No.2, 545-552, 2009.
(DOI: 10.1002/hep.22651,   PubMed: 19065675)
226. Kengo Kawai, Yoshinari Atarashi, Terumi Takahara, Hiroshi Kudo, Kazuto Tajiri, Yoshiharu Tokimitsu, Yasuhiro Nakayama, Katsuharu Hirano, Yutaka Yata, Masami Minemura, Satoshi Yasumura, Yasuharu Onishi, Kazuhiro Tsukada, Koichi Tsuneyama, Yasuo Takano and Toshiro Sugiyama :
Dietary supplement implicated in fulminant hepatic failure in a well-controlled Wilson disease patient.,
Clinical Journal of Gastroenterology, Vol.2, No.2, 119-124, 2009.
(DOI: 10.1007/s12328-008-0056-6,   PubMed: 26192177)
227. Willy Hsu, Weici Zhang, Koichi Tsuneyama, Yuki Moritoki, M William Ridgway, A Aftab Ansari, L Ross Coppel, Zhe-Xiong Lian, Ian Mackay and Eric M Gershwin :
Differential mechanisms in the pathogenesis of autoimmune cholangitis versus inflammatory bowel disease in interleukin-2Ralpha(-/-) mice.,
Hepatology, Vol.49, No.1, 133-140, 2009.
(DOI: 10.1002/hep.22591,   PubMed: 19065673)
228. Z Ruth Y Lan, L Thucydides Salunga, Koichi Tsuneyama, Zhe-Xiong Lian, Guo-Xiang Yang, Willy Hsu, Yuki Moritoki, A Aftab Ansari, Claudia Kemper, Jeff Price, P John Atkinson, L Ross Coppel and Eric M Gershwin :
Hepatic IL-17 responses in human and murine primary biliary cirrhosis.,
Journal of Autoimmunity, Vol.32, No.1, 43-51, 2008.
(DOI: 10.1016/j.jaut.2008.11.001,   PubMed: 19101114)
229. Ying-Yi Li, Yu Wu, Koichi Tsuneyama, Tomohisa Baba and Naofumi Mukaida :
Essential contribution of Ets-1 to constitutive Pim-3 expression in human pancreatic cancer cells.,
Cancer Science, Vol.100, No.3, 396-404, 2008.
(DOI: 10.1111/j.1349-7006.2008.01059.x,   PubMed: 19154409)
230. K Wakabayashi, K Yoshida, C P S Leung, Y Moritoki, G-X Yang, Koichi Tsuneyama, Z-X Lian, T Hibi, A A Ansari, S L Wicker, M W Ridgway, L R Coppel, R I Mackay and E M Gershwin :
Induction of autoimmune cholangitis in non-obese diabetic (NOD).1101 mice following a chemical xenobiotic immunization.,
Clinical and Experimental Immunology, Vol.155, No.3, 577-586, 2008.
(DOI: 10.1111/j.1365-2249.2008.03837.x,   PubMed: 19094117)
231. Hikari Suzuki, Ichiro Kato, Isao Usui, Ichiro Takasaki, Yoshiaki Tabuchi, Takeshi Oya, Koichi Tsuneyama, Hiroshi Kawaguchi, Koichi Hiraga, Shin Takasawa, Hiroshi Okamoto, Kazuyuki Tobe and Masakiyo Sasahara :
Characterization of diabetic nephropathy in CaM kinase IIalpha (Thr286Asp) transgenic mice.,
Biochemical and Biophysical Research Communications, Vol.379, No.1, 38-42, 2008.
(DOI: 10.1016/j.bbrc.2008.11.143,   PubMed: 19070598)
232. Yuki Moritoki, Weici Zhang, Koichi Tsuneyama, Katsunori Yoshida, Kanji Wakabayashi, Guo-Xiang Yang, Christopher Bowlus, M William Ridgway, Yoshiyuki Ueno, A Aftab Ansari, L Ross Coppel, R Ian Mackay, A Richard Flavell, Eric M Gershwin and Zhe-Xiong Lian :
B cells suppress the inflammatory response in a mouse model of primary biliary cirrhosis.,
Gastroenterology, Vol.136, No.3, 1037-1047, 2008.
(DOI: 10.1053/j.gastro.2008.11.035,   PubMed: 19118554)
233. Takuya Ishibe, Akihiko Kimura, Yuko Ishida, Tatsunori Takayasu, Takahito Hayashi, Koichi Tsuneyama, Kouji Matsushima, Ikuhiro Sakata, Naofumi Mukaida and Toshikazu Kondo :
Reduced acetaminophen-induced liver injury in mice by genetic disruption of IL-1 receptor antagonist.,
Laboratory Investigation; a Journal of Technical Methods and Pathology, Vol.89, No.1, 68-79, 2008.
(DOI: 10.1038/labinvest.2008.110,   PubMed: 19002106)
234. Kanji Wakabayashi, Zhe-Xiong Lian, C Patrick S Leung, Yuki Moritoki, Koichi Tsuneyama, J Mark Kurth, S Kit Lam, Katsunori Yoshida, Guo-Xiang Yang, Toshifumi Hibi, A Aftab Ansari, M William Ridgway, L Ross Coppel, R Ian Mackay and Eric M Gershwin :
Loss of tolerance in C57BL/6 mice to the autoantigen E2 subunit of pyruvate dehydrogenase by a xenobiotic with ensuing biliary ductular disease.,
Hepatology, Vol.48, No.2, 531-540, 2008.
(DOI: 10.1002/hep.22390,   PubMed: 18563844)
235. Yuko Nakanishi, Koichi Tsuneyama, Kazuhiro Nomoto, Makoto Fujimoto, L Thucydides Salunga, Takahiko Nakajima, Shigeharu Miwa, Yoshihiro Murai, Shinichi Hayashi, Ichiro Kato, Koichi Hiraga, K Daniel Hsu, Fu-Tong Liu and Yasuo Takano :
Nonalcoholic steatohepatitis and hepatocellular carcinoma in galectin-3 knockout mice.,
Hepatology Research, Vol.38, No.12, 1241-1251, 2008.
(DOI: 10.1111/j.1872-034X.2008.00395.x,   PubMed: 18637146)
236. Guo-Xiang Yang, Zhe-Xiong Lian, Ya-Hui Chuang, Yuki Moritoki, Y Ruth Lan, Kanji Wakabayashi, A Aftab Ansari, A Richard Flavell, M William Ridgway, L Ross Coppel, Koichi Tsuneyama, R Ian Mackay and Eric M Gershwin :
Adoptive transfer of CD8(+) T cells from transforming growth factor beta receptor type II (dominant negative form) induces autoimmune cholangitis in mice.,
Hepatology, Vol.47, No.6, 1974-1982, 2008.
(DOI: 10.1002/hep.22226,   PubMed: 18452147)
237. Katsuhisa Omagari, Shigeko Kato, Koichi Tsuneyama, Chisato Inohara, Yu Kuroda, Hiroe Tsukuda, Eri Fukazawa, Keiko Shiraishi and Masatoshi Mune :
Effects of a long-term high-fat diet and switching from a high-fat to low-fat, standard diet on hepatic fat accumulation in Sprague-Dawley rats.,
Digestive Diseases and Sciences, Vol.53, No.12, 3206-3212, 2008.
(DOI: 10.1007/s10620-008-0303-1,   PubMed: 18465233)
238. Yoshiharu Kawaguchi, Hirokazu Ishihara, Yumiko Abe, Shoji Seki, Ayano Tokunaga, Aya Urushizaki, Hiroyuki Takahashi, Koichi Tsuneyama and Tomoatsu Kimura :
Fatal prognosis of an atypical meningioma in the cervical spine.,
Journal of Orthopaedic Science, Vol.13, No.2, 155-159, 2008.
(DOI: 10.1007/s00776-007-1198-y,   PubMed: 18392921)
239. Shigeko Kato, Katsuhisa Omagari, Koichi Tsuneyama, Eri Fukazawa, Hiroe Tsukuda, Chisato Inohara, Yu Kuroda, Keiko Shiraishi and Masatoshi Mune :
A possible rat model for non-alcoholic steatohepatitis: Histological findings in SHR/NDmcr-cp rats.,
Hepatology Research, Vol.38, No.7, 743-744, 2008.
(DOI: 10.1111/j.1872-034X.2008.00342.x,   PubMed: 18371159)
240. Jiro Ogawa, Hirokazu Kanegane, Koichi Tsuneyama, Rika Kanezaki, Takeshi Futatani, Keiko Nomura, Shin Ishizawa, Masakiyo Sasahara, Etsuro Ito and Toshio Miyawaki :
Platelet-derived growth factor may be associated with fibrosis in a Down syndrome patient with transient myeloproliferative disorder.,
European Journal of Haematology, Vol.81, No.1, 58-64, 2008.
(DOI: 10.1111/j.1600-0609.2008.01061.x,   PubMed: 18331602)
241. Shinji Shimoda, Kenichi Harada, Hiroaki Niiro, Tomoharu Yoshizumi, Yuji Soejima, Akinobu Taketomi, Yoshihiko Maehara, Koichi Tsuneyama, Minoru Nakamura, Atsumasa Komori, Kiyoshi Migita, Yasuni Nakanuma, Hiromi Ishibashi, Carlo Selmi and Eric M Gershwin :
Biliary epithelial cells and primary biliary cirrhosis: the role of liver-infiltrating mononuclear cells.,
Hepatology, Vol.47, No.3, 958-965, 2008.
(DOI: 10.1002/hep.22102,   PubMed: 18181218)
242. Makoto Fujimoto, Koichi Tsuneyama, Mosaburo Kainuma, Nobuyasu Sekiya, Hirozo Goto, Yasuo Takano, Katsutoshi Terasawa, Carlo Selmi, Eric M Gershwin and Yutaka Shimada :
Evidence-based efficacy of Kampo formulas in a model of non alcoholic fatty liver.,
Experimental Biology and Medicine, Vol.233, No.3, 328-337, 2008.
(DOI: 10.3181/0707-RM-207,   PubMed: 18296738)
243. Tomohiko Kutsuna, Huachuan Zheng, Osman Hekmat Abdel-Aziz, Yoshihiro Murai, Koichi Tsuneyama, Isao Furuta and Yasuo Takano :
High JC virus load in tongue carcinomas may be a risk factor for tongue tumorigenesis.,
Virchows Archiv, Vol.452, No.4, 405-410, 2008.
(DOI: 10.1007/s00428-007-0534-0,   PubMed: 18283491)
244. Sabine Oertelt-Prigione, K Tin Mao, Carlo Selmi, Koichi Tsuneyama, A Aftab Ansari, L Ross Coppel, Pietro Invernizzi, Mauro Podda and Eric M Gershwin :
Impaired indoleamine 2,3-dioxygenase production contributes to the development of autoimmunity in primary biliary cirrhosis.,
Autoimmunity, Vol.41, No.1, 92-99, 2008.
(DOI: 10.1080/08916930701619730,   PubMed: 18176870)
245. Osman Hekmat Abdel-Aziz, Yoshihiro Murai, Ichiro Takasaki, Yoshiaki Tabuchi, Hua-chuan Zheng, Kazuhiro Nomoto, Hiroyuki Takahashi, Koichi Tsuneyama, Ichiro Kato, K Daniel Hsu, Fu-tong Liu, Koichi Hiraga and Yasuo Takano :
Targeted disruption of the galectin-3 gene results in decreased susceptibility to NNK-induced lung tumorigenesis: an oligonucleotide microarray study.,
Journal of Cancer Research and Clinical Oncology, Vol.134, No.7, 777-788, 2008.
(DOI: 10.1007/s00432-007-0345-3,   PubMed: 18204863)
246. Takuya Akashi, Keiichi Koizumi, Koichi Tsuneyama, Ikuo Saiki, Yasuo Takano and Hideki Fuse :
Chemokine receptor CXCR4 expression and prognosis in patients with metastatic prostate cancer.,
Cancer Science, Vol.99, No.3, 539-542, 2008.
(DOI: 10.1111/j.1349-7006.2007.00712.x,   PubMed: 18201276)
247. Kazuhiro Nomoto, Koichi Tsuneyama, Hiroyuki Takahashi, Yoshihiro Murai and Yasuo Takano :
Cytoplasmic fine granular expression of 8-hydroxydeoxyguanosine reflects early mitochondrial oxidative DNA damage in nonalcoholic fatty liver disease.,
Applied Immunohistochemistry & Molecular Morphology : AIMM, Vol.16, No.1, 71-75, 2008.
(DOI: 10.1097/PAI.0b013e31803156d5,   PubMed: 18091316)
248. Osman Hekmat Abdel-Aziz, Yoshihiro Murai, Mei Hong, Tomohiko Kutsuna, Hiroyuki Takahashi, Kazuhiro Nomoto, Shuichi Murata, Koichi Tsuneyama and Yasuo Takano :
Detection of the JC virus genome in lung cancers: possible role of the T-antigen in lung oncogenesis.,
Applied Immunohistochemistry & Molecular Morphology : AIMM, Vol.15, No.4, 394-400, 2007.
(DOI: 10.1097/01.pai.0000213126.96590.64,   PubMed: 18091381)
249. Huachuan Zheng, Hiroyuki Takahashi, Yoshihiro Murai, Zhengguo Cui, Kazuhiro Nomoto, Koichi Tsuneyama and Yasuo Takano :
Low expression of FHIT and PTEN correlates with malignancy of gastric carcinomas: tissue-array findings.,
Applied Immunohistochemistry & Molecular Morphology : AIMM, Vol.15, No.4, 432-440, 2007.
(DOI: 10.1097/01.pai.0000213127.96590.2d,   PubMed: 18091387)
250. Ichiro Nozaki, Takuo Watanabe, Makoto Kawaguchi, Hiroyasu Akatsu, Koichi Tsuneyama, Yasuhiko Yamamoto, Kazuyo Ohe, Hideto Yonekura, Masahito Yamada and Hiroshi Yamamoto :
Reduced expression of endogenous secretory receptor for advanced glycation endproducts in hippocampal neurons of Alzheimer's disease brains.,
Archives of Histology and Cytology, Vol.70, No.5, 279-290, 2007.
(DOI: 10.1679/aohc.70.279,   PubMed: 18431028)
251. Atsushi Tanaka, Koichi Tsuneyama, Masaki Mikami, Satoko Uegaki, Mitsuhiko Aiso and Hajime Takikawa :
Gene expression profiling in whole liver of bile duct ligated rats: VEGF-A expression is up-regulated in hepatocytes adjacent to the portal tracts.,
Journal of Gastroenterology and Hepatology, Vol.22, No.11, 1993-2000, 2007.
(DOI: 10.1111/j.1440-1746.2006.04629.x,   PubMed: 17914982)
252. Hua-Chuan Zheng, Koichi Tsuneyama, Hiroyuki Takahashi, Shigeharu Miwa, Toshiro Sugiyama, Konstantinova Boryana Popivanova, Chifumi Fujii, Kazuhiro Nomoto, Naofumi Mukaida and Yasuo Takano :
Aberrant Pim-3 expression is involved in gastric adenoma-adenocarcinoma sequence and cancer progression.,
Journal of Cancer Research and Clinical Oncology, Vol.134, No.4, 481-488, 2007.
(DOI: 10.1007/s00432-007-0310-1,   PubMed: 17876606)
253. Hiroyuki Takahashi, Yoshihiro Murai, Koichi Tsuneyama, Kazuhiro Nomoto, Eikichi Okada, Hideharu Fujita and Yasuo Takano :
High labeling indices of cdc25B is linked to progression of gastric cancers and associated with a poor prognosis.,
Applied Immunohistochemistry & Molecular Morphology : AIMM, Vol.15, No.3, 267-272, 2007.
(DOI: 10.1097/01.pai.0000213120.58472.57,   PubMed: 17721270)
254. L Thucydides Salunga, Yoshiaki Tabuchi, Ichiro Takasaki, B Loreto Feril, Qing-Li Zhao, Kenzo Ohtsuka, Koichi Tsuneyama and Takashi Kondo :
Identification of genes responsive to paeoniflorin, a heat shock protein-inducing compound, in human leukemia U937 cells.,
International Journal of Hyperthermia, Vol.23, No.6, 529-537, 2007.
(DOI: 10.1080/02656730701639499,   PubMed: 17952766)
255. C Patrick S Leung, Ogyi Park, Koichi Tsuneyama, J Mark Kurth, S Kit Lam, A Aftab Ansari, L Ross Coppel and Eric M Gershwin :
Induction of primary biliary cirrhosis in guinea pigs following chemical xenobiotic immunization.,
The Journal of Immunology, Vol.179, No.4, 2651-2657, 2007.
(DOI: 10.4049/jimmunol.179.4.2651,   PubMed: 17675529)
256. H Zheng, O Aziz H Abdel, Y Nakanishi, S Masuda, H Saito, Koichi Tsuneyama and Y Takano :
Oncogenic role of JC virus in lung cancer.,
The Journal of Pathology, Vol.212, No.3, 306-315, 2007.
(DOI: 10.1002/path.2188,   PubMed: 17534844)
257. Akihiko Takeuchi, Yasuhiko Yamamoto, Koichi Tsuneyama, Chunmei Cheng, Hideto Yonekura, Takuo Watanabe, Katsuji Shimizu, Katsuro Tomita, Hiroshi Yamamoto and Hiroyuki Tsuchiya :
Endogenous secretory receptor for advanced glycation endproducts as a novel prognostic marker in chondrosarcoma.,
Cancer, Vol.109, No.12, 2532-2540, 2007.
(DOI: 10.1002/cncr.22731,   PubMed: 17497647)
258. Sho Akai, Hiroko Hosomi, Keiichi Minami, Koichi Tsuneyama, Miki Katoh, Miki Nakajima and Tsuyoshi Yokoi :
Knock down of gamma-glutamylcysteine synthetase in rat causes acetaminophen-induced hepatotoxicity.,
The Journal of Biological Chemistry, Vol.282, No.33, 23996-24003, 2007.
(DOI: 10.1074/jbc.M702819200,   PubMed: 17573345)
259. Takahito Hayashi, Naho Hirayama, Ayako Ro, Norimasa Kageyama, Yuko Ishida, Koichi Tsuneyama, Akihiko Kimura, Tatsushige Fukunaga and Toshikazu Kondo :
Severe brainstem compression by an unruptured giant vertebral aneurysm--an autopsy case.,
Legal Medicine, Vol.9, No.6, 322-325, 2007.