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Tokushima University > Faculty of Medicine > School of Medicine > Course of Bioregulation and Medical Oncology > Pathology and Laboratory Medicine >
Tokushima University > Graduate School of Medical Sciences > Medical Science > Course of Bioregulation and Medical Oncology >
Tokushima University > Institute of Post-LED Photonics >
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Research Activity

Field of Study

Pathology

Subject of Study

肝臓病理学

Book / Paper

Book:

1. Minoru Matsumoto, Rodrigues M. Pedro, Sousa Laura, Koichi Tsuneyama, Mitsuru Matsumoto and Alves L. Nuno :
The Ins and Outs of Thymic Epithelial Cell Differentiation and Function,
Springer, Apr. 2019.
2. Hayato Baba, Ayumi Sugitani, Ryusei Takahashi, Kouki Kai, Yuki Moritoki, Kentaro Kikuchi and Koichi Tsuneyama :
Immunopathology of Bile Duct Lesions of Primary Biliary Cholangitis,
Springer Singapore, 2017.
(DOI: 10.1007/978-981-10-3500-5_6)

Academic Paper (Judged Full Paper):

1. Shoko Yamashita, Tetsuya Ikemoto, Yuji Morine, Satoru Imura, Shuichi Iwahashi, Mayu Saito, Shinichiro Yamada, Toshiaki Yoshimoto, Koichi Tsuneyama and Mitsuo Shimada :
Two cases of non-mucinous cystadenomas of the pancreas with pancreatobiliary phenotype and ovarian-like stroma.,
Surgical Case Reports, Vol.5, No.1, 2019.
(DOI: 10.1186/s40792-019-0673-y,   PubMed: 31338648)
2. Ru Jia, Shingo Oda, Koichi Tsuneyama, Yuya Urano and Tsuyoshi Yokoi :
Establishment of a mouse model of troglitazone-induced liver injury and analysis of its hepatotoxic mechanism.,
Journal of Applied Toxicology : JAT, 2019.
(DOI: 10.1002/jat.3838,   PubMed: 31294483)
3. Fuhua Yang, Taiki Takeuchi, Koichi Tsuneyama, Tsuyoshi Yokoi and Shingo Oda :
Experimental Evidence of Liver Injury by BSEP-Inhibiting Drugs With a Bile Salt Supplementation in Rats.,
Toxicological Sciences, Vol.170, No.1, 95-108, 2019.
(DOI: 10.1093/toxsci/kfz088,   PubMed: 30985903)
4. Tetsuyuki Takahashi, Hirona Ichikawa, Yuuki Morimoto, Koichi Tsuneyama and Takao Hijikata :
Inhibition of EP2/EP4 prostanoid receptor-mediated signaling suppresses IGF-1-induced proliferation of pancreatic cancer BxPC-3 cells via upregulating γ-glutamyl cyclotransferase expression.,
Biochemical and Biophysical Research Communications, Vol.516, No.2, 388-396, 2019.
(DOI: 10.1016/j.bbrc.2019.06.054,   PubMed: 31217077)
5. Ayaka Iida, Sachi Kuranuki, Ryoko Yamamoto, Masaya Uchida, Masanori Ohta, Mayuko Ichimura, Koichi Tsuneyama, Takayuki Masaki, Masataka Seike and Tsuyoshi Nakamura :
Analysis of amino acid profiles of blood over time and biomarkers associated with non-alcoholic steatohepatitis in STAM mice.,
Experimental Animals, 2019.
(DOI: 10.1538/expanim.18-0152,   PubMed: 31155606)
6. Akiko Takikawa, Isao Usui, Shiho Fujisaka, Koichi Tsuneyama, Keisuke Okabe, Takashi Nakagawa, Allah Nawaz, Tomonobu Kado, Teruo Jojima, Yoshimasa Aso, Yoshihiro Hayakawa, Kunikimi Yagi and Kazuyuki Tobe :
Macrophage-specific hypoxia-inducible factor-1α deletion suppresses the development of liver tumors in high-fat diet-fed obese and diabetic mice.,
Journal of Diabetes Investigation, 2019.
(DOI: 10.1111/jdi.13047,   PubMed: 30897274)
7. Makoto Kurano, Koichi Tsuneyama, Yuki Morimoto, Masako Nishikawa and Yutaka Yatomi :
Apolipoprotein M suppresses the phenotypes of IgA nephropathy in hyper-IgA mice.,
The FASEB journal, Vol.33, No.4, 5181-5195, 2019.
(DOI: 10.1096/fj.201801748R,   PubMed: 30629456,   Elsevier: Scopus)
8. Yuki Izawa-Ishizawa, Masaki Imanishi, Yoshito Zamami, Toya Hiroki, Nagao Tomoko, Marin Morishita, Koichi Tsuneyama, Yuya Horinouchi, Yoshitaka Kihira, Kenshi Takechi, Yasumasa Ikeda, Koichiro Tsuchiya, Masanori Yoshizumi, Toshiaki Tamaki and Keisuke Ishizawa :
Development of a novel aortic dissection mouse model and evaluation of drug efficacy using in-vivo assays and database analyses.,
Journal of Hypertension, Vol.37, No.1, 73-83, 2019.
(Tokushima University Institutional Repository: 113264,   DOI: 10.1097/HJH.0000000000001898,   PubMed: 30303488)
9. Junko Morimoto, Yumiko Nishikawa, Takumi Kakimoto, Kohei Furutani, Naoki Kihara, Minoru Matsumoto, Koichi Tsuneyama, Yuko Kozono, Haruo Kozono, Katsuto Hozumi, Kazuyoshi Hosomichi, Hitoshi Nishijima and Mitsuru Matsumoto :
Aire Controls in Trans the Production of Medullary Thymic Epithelial Cells Expressing Ly-6C/Ly-6G.,
The Journal of Immunology, Vol.201, No.11, 3244-3257, 2018.
(DOI: 10.4049/jimmunol.1800950,   PubMed: 30389776)
10. Yuki Moritoki, Koichi Tsuneyama, Yuka Nakamura, Kentaro Kikuchi, Akira Shiota, Yoshiyuki Ohsugi, Zhe-Xiong Lian, Weici Zhang, Guo-Xiang Yang, Shigeharu Ueki, Masahide Takeda, Ayumi Omokawa, Tomoo Saga, Akiko Saga, Daisuke Watanabe, Masahito Miura, Yoshiyuki Ueno, C Patrick S Leung, Atsushi Tanaka, Eric M Gershwin and Makoto Hirokawa :
Anti-drug Antibodies Against a Novel Humanized Anti-CD20 Antibody Impair Its Therapeutic Effect on Primary Biliary Cholangitis in Human CD20- and FcγR-Expressing Mice.,
Frontiers in Immunology, Vol.9, 2018.
(DOI: 10.3389/fimmu.2018.02534,   PubMed: 30450101)
11. Kazuchika Nishitsuji, Syunsuke Watanabe, Jinzhong Xiao, Ryosuke Nagatomo, Hirohisa Ogawa, Takaaki Tsunematsu, Hitomi Umemoto, Yuki Morimoto, Hiroyasu Akatsu, Koichi Inoue and Koichi Tsuneyama :
Effect of coffee or coffee components on gut microbiome and short-chain fatty acids in a mouse model of metabolic syndrome.,
Scientific Reports, Vol.8, No.1, 2018.
(DOI: 10.1038/s41598-018-34571-9,   PubMed: 30385796)
12. Hong-Di Ma, Zhi-Bin Zhao, Wen-Tao Ma, Qing-Zhi Liu, Cai-Yue Gao, Liang Li, Jinjun Wang, Koichi Tsuneyama, Bin Liu, Weici Zhang, Yongjian Zhou, Eric M Gershwin and Zhe-Xiong Lian :
Gut microbiota translocation promotes autoimmune cholangitis.,
Journal of Autoimmunity, Vol.95, 47-57, 2018.
(DOI: 10.1016/j.jaut.2018.09.010,   PubMed: 30340822,   Elsevier: Scopus)
13. Hirohisa Ogawa, Masahiko Azuma, Takaaki Tsunematsu, Yuuki Morimoto, Mayo Kondo, Toshifumi Tezuka, Yasuhiko Nishioka and Koichi Tsuneyama :
Neutrophils induce smooth muscle hyperplasia via neutrophil elastase-induced FGF-2 in a mouse model of asthma with mixed inflammation.,
Clinical and Experimental Allergy, Vol.48, No.12, 1715-1725, 2018.
(DOI: 10.1111/cea.13263,   PubMed: 30171733)
14. Yuya Urano, Shingo Oda, Koichi Tsuneyama and Tsuyoshi Yokoi :
Comparative hepatic transcriptome analyses revealed possible pathogenic mechanisms of fasiglifam (TAK-875)-induced acute liver injury in mice.,
Chemico-Biological Interactions, Vol.296, 185-197, 2018.
(DOI: 10.1016/j.cbi.2018.09.011,   PubMed: 30243991)
15. Katsuhisa Omagari, Ayumi Fukuda, Machiko Suga, Ayumi Ogata, Shinta Nishioka, Kazuhito Suruga, Mayuko Ichimura and Koichi Tsuneyama :
Peptides Obtained by Enzymatic Decomposition of Mackerel Prevent Nonalcoholic Steatohepatitis in Sprague-Dawley Rats fed a High-fat and High-cholesterol Diet,
OBM Hepatology and Gastroenterology, Vol.2, No.3, 2018.
(DOI: 10.21926/obm.hg.1803008)
16. Mayo Kondo, Hirokazu Ogino, Hirohisa Ogawa, Tania Afroj, Yuko Toyoda, Satoshi Sakaguchi, Miki Tsuboi, Yoshimi Bando, Hisatsugu Goto, Koichi Tsuneyama and Yasuhiko Nishioka :
A case of pulmonary pleomorphic carcinoma with malignant phenotypes induced by ZEB1-associated epithelial-mesenchymal transition.,
Respiratory Medicine Case Reports, Vol.25, 119-121, 2018.
(DOI: 10.1016/j.rmcr.2018.07.008,   PubMed: 30112272)
17. Ryosuke Nagatomo, Yasuki Okada, Mayuko Ichimura, Koichi Tsuneyama and Koichi Inoue :
Application of 2-Picolylamine Derivatized Ultra-high Performance Liquid Chromatography Tandem Mass Spectrometry for Determination of Short-chain Fatty Acids in Feces Samples.,
Analytical Sciences, Vol.34, No.9, 1031-1036, 2018.
(DOI: 10.2116/analsci.18SCP10,   PubMed: 30078818)
18. Kaizo Kagemoto, Koichi Okamoto, Tohshi Takaoka, Yasushi Sato, Shinji Kitamura, Tetsuo Kimura, Masahiro Sogabe, Hiroshi Miyamoto, Naoki Muguruma, Koichi Tsuneyama and Tetsuji Takayama :
Detection of aberrant crypt foci with image-enhanced endoscopy.,
Endoscopy International Open, Vol.6, No.8, E924-E933, 2018.
(DOI: 10.1055/a-0621-8794,   PubMed: 30123821)
19. Cai-Yue Gao, Yuan Yao, Liang Li, Shu-Han Yang, Hui Chu, Koichi Tsuneyama, Xiao-Mei Li, M Gershwin Eric and Zhe-Xiong Lian :
Tissue resident memory CD8 T cells mediate salivary gland damage in a murine model of Sjögren's syndrome.,
Arthritis & Rheumatology, 2018.
(DOI: 10.1002/art.40676,   PubMed: 30035379)
20. Masaki Takeuchi, Shingo Oda, Koichi Tsuneyama and Tsuyoshi Yokoi :
Comprehensive analysis of serum microRNAs in hepatic sinusoidal obstruction syndrome (SOS) in rats: implication as early phase biomarkers for SOS.,
Archives of Toxicology, 2018.
(DOI: 10.1007/s00204-018-2269-x,   PubMed: 30019166)
21. Makoto Kurano, Koichi Tsuneyama, Yuki Morimoto, Tomo Shimizu, Masahiro Jona, Hidetoshi Kassai, Kazuki Nakao, Atsu Aiba and Yutaka Yatomi :
Apolipoprotein M Protects Lipopolysaccharide-Treated Mice from Death and Organ Injury.,
Thrombosis and Haemostasis, 2018.
(DOI: 10.1055/s-0038-1641750,   PubMed: 29669385)
22. Akiko Matsubara, Shingo Oda, Sho Akai, Koichi Tsuneyama and Tsuyoshi Yokoi :
Establishment of a drug-induced rhabdomyolysis mouse model by co-administration of ciprofloxacin and atorvastatin.,
Toxicology Letters, Vol.291, 184-193, 2018.
(DOI: 10.1016/j.toxlet.2018.04.016,   PubMed: 29679711)
23. Tetsuyuki Takahashi, Ulrich Deuschle, Shu Taira, Takeshi Nishida, Makoto Fujimoto, Takao Hijikata and Koichi Tsuneyama :
Tsumura-Suzuki obese diabetic mice-derived hepatic tumors closely resemble human hepatocellular carcinomas in metabolism-related genes expression and bile acid accumulation.,
Hepatology International, Vol.12, No.3, 254-261, 2018.
(Tokushima University Institutional Repository: 112472,   DOI: 10.1007/s12072-018-9860-3,   PubMed: 29651702,   Elsevier: Scopus)
24. Shota Fujimoto, Naoki Muguruma, Koichi Okamoto, Takeshi Kurihara, Yasushi Sato, Yoshihiko Miyamoto, Shinji Kitamura, Hiroshi Miyamoto, Takahiro Taguchi, Koichi Tsuneyama and Tetsuji Takayama :
A Novel Theranostic Combination of Near-infrared Fluorescence Imaging and Laser Irradiation Targeting c-KIT for Gastrointestinal Stromal Tumors.,
Theranostics, Vol.8, No.9, 2313-2328, 2018.
(DOI: 10.7150/thno.22027,   PubMed: 29721082,   Elsevier: Scopus)
25. Momoko Akashi, Kazuto Tajiri, Akinori Wada, Koichi Tsuneyama, Kengo Kawai, Satoshi Yasumura, Masami Minemura, Terumi Takahara and Toshiro Sugiyama :
A Patient with Non-alcoholic Steatohepatitis Complicated by Multiple Myeloma.,
Internal Medicine, 2018.
(DOI: 10.2169/internalmedicine.0092-17,   PubMed: 29491288)
26. Satoru Joshita, Kaname Yoshizawa, Takeji Umemura, Hiromasa Ohira, Atsushi Takahashi, Kenichi Harada, Canh Nguyen Hiep, Koichi Tsuneyama, Masayoshi Kage, Masayuki Nakano, Jong-Hon Kang, Kazuhiko Koike, Mikio Zeniya, Tetsuya Yasunaka, Akinobu Takaki, Takuji Torimura, Masanori Abe, Osamu Yokosuka, Atsushi Tanaka and Hajime Takikawa :
Clinical features of autoimmune hepatitis with acute presentation: a Japanese nationwide survey.,
Journal of Gastroenterology, 2018.
(DOI: 10.1007/s00535-018-1444-4,   PubMed: 29476251)
27. Shingo Oda, Masaki Takeuchi, Sho Akai, Yuji Shirai, Koichi Tsuneyama and Tsuyoshi Yokoi :
miRNA in Rat Liver Sinusoidal Endothelial Cells and Hepatocytes and Application to Circulating Biomarkers that Discern Pathogenesis of Liver Injuries.,
The American Journal of Pathology, Vol.188, No.4, 916-928, 2018.
(DOI: 10.1016/j.ajpath.2017.12.007,   PubMed: 29353062)
28. Hitoshi Nishijima, Tatsuya Kajimoto, Yoshiki Matsuoka, Yasuhiro Mouri, Junko Morimoto, Minoru Matsumoto, Hiroshi Kawano, Yasuhiko Nishioka, Hisanori Uehara, Keisuke Izumi, Koichi Tsuneyama, Il-mi Okazaki, Taku Okazaki, Kazuyoshi Hosomichi, Ayako Shiraki, Makoto Shibutani, Kunitoshi Mitsumori and Mitsuru Matsumoto :
Paradoxical development of polymyositis-like autoimmunity through augmented expression of autoimmune regulator (AIRE).,
Journal of Autoimmunity, Vol.86, 75-92, 2018.
(Tokushima University Institutional Repository: 112347,   DOI: 10.1016/j.jaut.2017.09.006,   PubMed: 28931462)
29. Kazuchika Nishitsuji, Jinzhong Xiao, Ryosuke Nagatomo, Hitomi Umemoto, Yuki Morimoto, Hiroyasu Akatsu, Koichi Inoue and Koichi Tsuneyama :
Analysis of the gut microbiome and plasma short-chain fatty acid profiles in a spontaneous mouse model of metabolic syndrome.,
Scientific Reports, Vol.7, No.1, 15876, 2017.
(Tokushima University Institutional Repository: 112394,   DOI: 10.1038/s41598-017-16189-5,   PubMed: 29158587)
30. Shohei Yamashita, Shingo Oda, Hideko Endo, Koichi Tsuneyama and Tsuyoshi Yokoi :
Neutrophil depletion protects against zomepirac-induced acute kidney injury in mice.,
Chemico-Biological Interactions, Vol.279, 102-110, 2017.
(DOI: 10.1016/j.cbi.2017.11.011,   PubMed: 29154782,   Elsevier: Scopus)
31. Yasuhiro Mouri, Yoshihiro Ueda, Tomoyoshi Yamano, Minoru Matsumoto, Koichi Tsuneyama, Tatsuo Kinashi and Mitsuru Matsumoto :
Mode of tolerance induction and requirement for Aire are governed by the cell types that express self-antigen and those that present antigen,
The Journal of Immunology, Vol.199, No.12, 3959-3971, 2017.
(DOI: 10.4049/jimmunol.1700892,   PubMed: 29101311,   Elsevier: Scopus)
32. Akemi Tsutsui, Kenichi Harada, Koichi Tsuneyama, Tomonori Senoh, Takuya Nagano, Koichi Takaguchi, Midori Ando, Satoko Nakamura, Koichi Mizobuchi and Masatoshi Kudo :
Clinicopathological Study of Autoimmune Hepatitis Cases That Were Difficult to Differentiate from Drug-Induced Liver Injury.,
Digestive Diseases, Vol.35, No.6, 506-514, 2017.
(DOI: 10.1159/000480139,   PubMed: 29040982)
33. Koichi Tsuneyama, Kazuchika Nishitsuji, Minoru Matsumoto, Tomoko Kobayashi, Yuki Morimoto, Takaaki Tsunematsu and Hirohisa Ogawa :
Animal models for analyzing metabolic syndrome-associated liver diseases.,
Pathology International, Vol.67, No.11, 539-546, 2017.
(DOI: 10.1111/pin.12600,   PubMed: 29027308)
34. R Heekyong Bae, L Deborah Hodge, Guo-Xiang Yang, C Patrick S Leung, Babu Sathi Chodisetti, C Julio Valencia, Michael Sanford, M John Fenimore, M Ziaur S Rahman, Koichi Tsuneyama, L Gary Norman, Eric M Gershwin and A Howard Young :
The interplay of type I and type II interferons in murine autoimmune cholangitis as a basis for sex-biased autoimmunity.,
Hepatology, Vol.67, No.4, 1408-1419, 2017.
(DOI: 10.1002/hep.29524,   PubMed: 28921595,   Elsevier: Scopus)
35. Hayato Baba, Makoto Kurano, Takeshi Nishida, Hideki Hatta, Ryoji Hokao and Koichi Tsuneyama :
Facilitatory effect of insulin treatment on hepatocellular carcinoma development in diabetes.,
BMC Research Notes, Vol.10, No.1, 478, 2017.
(DOI: 10.1186/s13104-017-2783-6,   PubMed: 28903776)
36. Allah Nawaz, Aminuddin Aminuddin, Tomonobu Kado, Akiko Takikawa, Seiji Yamamoto, Koichi Tsuneyama, Yoshiko Igarashi, Masashi Ikutani, Yasuhiro Nishida, Yoshinori Nagai, Kiyoshi Takatsu, Johji Imura, Masakiyo Sasahara, Yukiko Okazaki, Kohjiro Ueki, Tadashi Okamura, Kumpei Tokuyama, Akira Ando, Michihiro Matsumoto, Hisashi Mori, Takashi Nakagawa, Norihiko Kobayashi, Kumiko Saeki, Isao Usui, Shiho Fujisaka and Kazuyuki Tobe :
CD206(+) M2-like macrophages regulate systemic glucose metabolism by inhibiting proliferation of adipocyte progenitors.,
Nature Communications, Vol.8, No.1, 286, 2017.
(Tokushima University Institutional Repository: 112461,   DOI: 10.1038/s41467-017-00231-1,   PubMed: 28819169)
37. Katsuhisa Omagari, Kazuhito Suruga, Akira Kyogoku, Satomi Nakamura, Ai Sakamoto, Shinta Nishioka, Mayuko Ichimura, Yuji Miyata, Koichi Tajima, Koichi Tsuneyama and Kazunari Tanaka :
A fermented mixed tea made with camellia (Camellia japonica) and third-crop green tea leaves prevents nonalcoholic steatohepatitis in Sprague-Dawley rats fed a high-fat and high-cholesterol diet.,
Hepatobiliary Surgery and Nutrition, Vol.7, No.3, 175-184, 2017.
(DOI: 10.21037/hbsn.2017.08.03,   PubMed: 30046568)
38. Kotaro Matsumoto, Mayuko Ichimura, Koichi Tsuneyama, Yuki Moritoki, Hiromichi Tsunashima, Katsuhisa Omagari, Masumi Hara, Ichiro Yasuda, Hiroshi Miyakawa and Kentaro Kikuchi :
Fructo-oligosaccharides and intestinal barrier function in a methionine-choline-deficient mouse model of nonalcoholic steatohepatitis.,
PLoS ONE, Vol.12, No.6, e0175406, 2017.
(Tokushima University Institutional Repository: 112342,   DOI: 10.1371/journal.pone.0175406,   PubMed: 28632732)
39. Mayumi Takeuchi, Kenji Matsuzaki, Koichi Tsuneyama, Masato Nishimura, Eri Takiguchi and Masafumi Harada :
Ovarian Large Cell Neuroendocrine Carcinoma Associated with Serous Carcinoma: Correlation of Pathology with MR Imaging,
Magnetic Resonance in Medical Sciences, Vol.16, No.4, 273-274, 2017.
(DOI: 10.2463/mrms.ci.2016-0150,   PubMed: 28566585,   Elsevier: Scopus)
40. Seitarou Shimada, Kazuto Tajiri, Hayato Baba, Masami Minemura, Koichi Tsuneyama, Masayuki Nakano and Toshiro Sugiyama :
Peritumoral Hyperplasia in Hepatic Sclerosed Hemangioma.,
ACG Case Reports Journal, Vol.4, e61, 2017.
(DOI: 10.14309/crj.2017.61,   PubMed: 28462238)
41. Hiep Canh Nguyen, Kenichi Harada, Hirofumi Ouchi, Yasunori Sato, Koichi Tsuneyama, Masayoshi Kage, Masayuki Nakano, Kaname Yoshizawa, Atsushi Takahashi, Masanori Abe, Jong-Hon Kang, Kazuhiko Koike, Ayano Inui, Tomoo Fujisawa, Akinobu Takaki, Teruko Arinaga-Hino, Takuji Torimura, Yoshiyuki Suzuki, Keiichi Fujiwara, Mikio Zeniya, Hiromasa Ohira, Atsushi Tanaka and Hajime Takikawa :
Acute presentation of autoimmune hepatitis: a multicentre study with detailed histological evaluation in a large cohort of patients.,
Journal of Clinical Pathology, 2017.
(DOI: 10.1136/jclinpath-2016-204271,   PubMed: 28428284)
42. Masashi Ikutani, Koichi Tsuneyama, Makoto Kawaguchi, Junya Fukuoka, Fujimi Kudo, Susumu Nakae, Makoto Arita, Yoshinori Nagai, Satoshi Takaki and Kiyoshi Takatsu :
Prolonged activation of IL-5-producing ILC2 causes pulmonary arterial hypertrophy.,
JCI Insight, Vol.2, No.7, e90721, 2017.
(DOI: 10.1172/jci.insight.90721,   PubMed: 28405615)
43. Syunsuke Watanabe, Tetsuyuki Takahashi, Hirohisa Ogawa, Hisanori Uehara, Takaaki Tsunematsu, Hayato Baba, Yuki Morimoto and Koichi Tsuneyama :
Daily Coffee Intake Inhibits Pancreatic Beta Cell Damage and Nonalcoholic Steatohepatitis in a Mouse Model of Spontaneous Metabolic Syndrome, Tsumura-Suzuki Obese Diabetic Mice.,
Metabolic Syndrome and Related Disorders, Vol.15, No.4, 170-177, 2017.
(DOI: 10.1089/met.2016.0114,   PubMed: 28358620)
44. Cindy Chang, Ana Lleo, Anchasa Kananurak, Fabio Grizzi, Koichi Tsuneyama, Pietro Invernizzi, L Charles Bevins and L Christopher Bowlus :
Human -Defensin 2 in Primary Sclerosing Cholangitis.,
Clinical and Translational Gastroenterology, Vol.8, No.3, e80, 2017.
(DOI: 10.1038/ctg.2017.8,   PubMed: 28300822)
45. Yuji Shirai, Shingo Oda, Sayaka Makino, Koichi Tsuneyama and Tsuyoshi Yokoi :
Establishment of a mouse model of enalapril-induced liver injury and investigation of the pathogenesis.,
Laboratory Investigation; a Journal of Technical Methods and Pathology, Vol.97, No.7, 833-842, 2017.
(DOI: 10.1038/labinvest.2017.22,   PubMed: 28263289)
46. Hong-Di Ma, Wen-Tao Ma, Qing-Zhi Liu, Zhi-Bin Zhao, Mu-Zi-Ying Liu, Koichi Tsuneyama, Jin-Ming Gao, M William Ridgway, A Aftab Ansari, Eric M Gershwin, Yun-Yun Fei and Zhe-Xiong Lian :
Chemokine receptor CXCR3 deficiency exacerbates murine autoimmune cholangitis by promoting pathogenic CD8(+) T cell activation.,
Journal of Autoimmunity, Vol.78, 19-28, 2017.
(DOI: 10.1016/j.jaut.2016.12.012,   PubMed: 28129932)
47. Koichi Tsuneyama, Hayato Baba, Yuki Morimoto, Takaaki Tsunematsu and Hirohisa Ogawa :
Primary Biliary Cholangitis: Its Pathological Characteristics and Immunopathological Mechanisms.,
The Journal of Medical Investigation : JMI, Vol.64, No.1.2, 7-13, 2017.
(Tokushima University Institutional Repository: 111056,   DOI: 10.2152/jmi.64.7,   PubMed: 28373632)
48. Shota Morimoto, Tomoya Ishikawa, Kumoinori Hyodo, Takahiro Yamazaki, Shu Taira, Koichi Tsuneyama and Yuko Iciyanagi :
Preparation and characterization of newly developed matrix using functional γ-Fe2O3 nanoparticles for mass spectrometry in small molecules.,
Surface and Interface Analysis, Vol.48, No.11, 1127-1131, 2016.
(DOI: 10.1002/sia.6100)
49. Mayuko Ichimura, Miki Masuzumi, Miku Kawase, Mika Sakaki, Shizuka Tamaru, Yasuo Nagata, Kazunari Tanaka, Kazuhito Suruga, Koichi Tsuneyama, Satoru Matsuda and Katsuhisa Omagari :
A diet-induced Sprague-Dawley rat model of nonalcoholic steatohepatitis-related cirrhosis.,
The Journal of Nutritional Biochemistry, Vol.40, 62-69, 2016.
(DOI: 10.1016/j.jnutbio.2016.10.007,   PubMed: 27863346)
50. Makoto Kawaguchi, Noboru Hara, Vladimir Bilim, Hiroshi Koike, Mituko Suzuki, Tae-Sun Kim, Nan Gao, Yu Dong, Sheng Zhang, Yuji Fujinawa, Osamu Yamamoto, Hiromi Ito, Yoshihiko Tomita, Yuchi Naruse, Akira Sakamaki, Yoko Ishii, Koichi Tsuneyama, Masaaki Inoue, Johbu Itoh, Masanori Yasuda, Nobuo Sakata, Cha-Gyun Jung, Satoshi Kanazawa, Hiroyasu Akatsu, Hiroshi Minato, Takayuki Nojima, Kiyofumi Asai and Yutaka Miura :
A diagnostic marker for superficial urothelial bladder carcinoma: lack of nuclear ATBF1 (ZFHX3) by immunohistochemistry suggests malignant progression.,
BMC Cancer, Vol.16, No.1, 805, 2016.
(DOI: 10.1186/s12885-016-2845-5,   PubMed: 27756245)
51. Takeshi Nishida, Koichi Tsuneyama, Makoto Fujimoto, Kazuhiro Nomoto, Shinichi Hayashi, Shigeharu Miwa, Takahiko Nakajima, Yuko Nakanishi, Hideki Hatta and Johji Imura :
Aberrant iron metabolism might have an impact on progression of diseases in Tsumura Suzuki obese diabetes mice, a model of spontaneous metabolic syndrome.,
Pathology International, Vol.66, No.11, 622-628, 2016.
(DOI: 10.1111/pin.12466,   PubMed: 27687701)
52. Shingo Oda, Yuji Shirai, Sho Akai, Akira Nakajima, Koichi Tsuneyama and Tsuyoshi Yokoi :
Toxicological role of an acyl glucuronide metabolite in diclofenac-induced acute liver injury in mice.,
Journal of Applied Toxicology : JAT, Vol.37, No.5, 545-553, 2016.
(DOI: 10.1002/jat.3388,   PubMed: 27671914)
53. Akiko Takikawa, Arshad Mahmood, Allah Nawaz, Tomonobu Kado, Keisuke Okabe, Seiji Yamamoto, Aminuddin Aminuddin, Satoko Senda, Koichi Tsuneyama, Masashi Ikutani, Yasuharu Watanabe, Yoshiko Igarashi, Yoshinori Nagai, Kiyoshi Takatsu, Keiichi Koizumi, Johji Imura, Nobuhito Goda, Masakiyo Sasahara, Michihiro Matsumoto, Kumiko Saeki, Takashi Nakagawa, Shiho Fujisaka, Isao Usui and Kazuyuki Tobe :
HIF-1 in Myeloid Cells Promotes Adipose Tissue Remodeling Toward Insulin Resistance.,
Diabetes, Vol.65, No.12, 3649-3659, 2016.
(DOI: 10.2337/db16-0012,   PubMed: 27625023)
54. Tetsuyuki Takahashi, Takeshi Nishida, Hayato Baba, Hideki Hatta, Johji Imura, Mitsuko Sutoh, Syunji Toyohara, Ryoji Hokao, Syunsuke Watanabe, Hirohisa Ogawa, Hisanori Uehara and Koichi Tsuneyama :
Histopathological characteristics of glutamine synthetase-positive hepatic tumor lesions in a mouse model of spontaneous metabolic syndrome (TSOD mouse).,
Molecular and Clinical Oncology, Vol.5, No.2, 267-270, 2016.
(DOI: 10.3892/mco.2016.924,   PubMed: 27446562)
55. G-X Yang, Y Sun, Koichi Tsuneyama, W Zhang, P S. C. Leung, X-S He, A A. Ansari, C Bowlus, W M. Ridgway and M E. Gershwin :
Endogenous interleukin-22 protects against inflammatory bowel disease but not autoimmune cholangitis in dominant negative form of transforming growth factor beta receptor type II mice.,
Clinical and Experimental Immunology, Vol.185, No.2, 154-164, 2016.
(DOI: 10.1111/cei.12806,   PubMed: 27148790)
56. Heekyong R. Bae, Patrick S. C. Leung, Koichi Tsuneyama, Julio C. Valencia, Deborah L. Hodge, Seohyun Kim, Tim Back, Megan Karwan, Anand S. Merchant, Nobuyuki Baba, Dechun Feng, Ogyi Park, Bin Gao, Guo-Xiang Yang, M Gershwin Eric and Howard A. Young :
Chronic Expression of Interferon Gamma Leads to Murine Autoimmune Cholangitis with a Female Predominance.,
Hepatology, Vol.64, No.4, 1189-1201, 2016.
(DOI: 10.1002/hep.28641,   PubMed: 27178326,   Elsevier: Scopus)
57. Atsushi Iwamura, Katsuhito Watanabe, Sho Akai, Tsubasa Nishinosono, Koichi Tsuneyama, Shingo Oda, Toshiyuki Kume and Tsuyoshi Yokoi :
Zomepirac Acyl Glucuronide Is Responsible for Zomepirac-Induced Acute Kidney Injury in Mice.,
Drug Metabolism and Disposition, Vol.44, No.7, 888-896, 2016.
(DOI: 10.1124/dmd.116.069575,   PubMed: 27112166)
58. Akiko Takikawa, Shiho Fujisaka, Masashi Ikutani, Satoko Senda, Shinpei Hattori, Koichi Tsuneyama, Yukiko Koshimizu, Ran Inoue, Ayumi Tanaka-Hayashi, Takashi Nakagawa, Yoshinori Nagai, Kiyoshi Takatsu, Toshiyasu Sasaoka, Hisashi Mori and Kazuyuki Tobe :
Deletion of SIRT1 in myeloid cells impairs glucose metabolism with enhancing inflammatory response to adipose tissue hypoxia,
Diabetology International, Vol.7, No.1, 59-68, 2016.
(DOI: 10.1007/s13340-015-0213-3,   Elsevier: Scopus)
59. Takahiko Nakajima, Haruo Yagi, Hayato Baba, Takashi Minamisaka, Shigeharu Miwa, Shinichi Hayashi, Takeshi Nishida, Hideki Hatta, Koichi Tsuneyama and Johji Imura :
Complete Resolution of Pseudomalignant Erosion in a Reflux Gastroesophageal Polyp with Proton Pump Inhibitor.,
Case Reports in Pathology, Vol.2015, 2015.
(DOI: 10.1155/2015/657059,   PubMed: 26688768)
60. Haruka Wakae, Tomomi Higashide, Koichi Tsuneyama, Takahiro Nakamura, Kanji Takahashi and Kazuhisa Sugiyama :
Immunohistochemical Characterization of the Ectopic Epithelium Devoid of Goblet Cells From a Posttraumatic Iris Cyst Causing Mucogenic Glaucoma.,
Journal of Glaucoma, 2015.
(DOI: 10.1097/IJG.0000000000000346,   PubMed: 26550968)
61. Jing-Bo Yang, Yin-Hu Wang, Wei Yang, Fang-Ting Lu, Hong-Di Ma, Zhi-Bin Zhao, Yan-Jie Jia, Wei Tang, Koichi Tsuneyama, M William Ridgway, Eric M Gershwin and Zhe-Xiong Lian :
Successful treatment of murine autoimmune cholangitis by parabiosis: Implications for hematopoietic therapy.,
Journal of Autoimmunity, Vol.66, 108-117, 2015.
(DOI: 10.1016/j.jaut.2015.09.002,   PubMed: 26432598)
62. Hiromichi Tsunashima, Koichi Tsuneyama, Yuki Moritoki, Masumi Hara and Kentaro Kikuchi :
Accumulated myeloid-derived suppressor cells demonstrate distinct phenotypes and functions in two non-alcoholic steatohepatitis mouse models.,
Hepatobiliary Surgery and Nutrition, Vol.4, No.5, 313-319, 2015.
(DOI: 10.3978/j.issn.2304-3881.2015.04.08,   PubMed: 26605278)
63. Eita Sasaki, Azumi Iida, Shingo Oda, Koichi Tsuneyama, Tatsuki Fukami, Miki Nakajima and Tsuyoshi Yokoi :
Pathogenetic analyses of carbamazepine-induced liver injury in F344 rats focused on immune- and inflammation-related factors.,
Experimental and Toxicologic Pathology, 2015.
(DOI: 10.1016/j.etp.2015.09.004,   PubMed: 26391595)
64. Sho Akai, Yasuaki Uematsu, Koichi Tsuneyama, Shingo Oda and Tsuyoshi Yokoi :
Kupffer cell-mediated exacerbation of methimazole-induced acute liver injury in rats.,
Journal of Applied Toxicology : JAT, 2015.
(DOI: 10.1002/jat.3202,   PubMed: 26177832,   Elsevier: Scopus)
65. Zheng-Guo Cui, Ryohei Ogawa, Koichi Tsuneyama, Gen Yan, Lingling Tao, Akiko Shimomura and Hidekuni Inadera :
Insight into the molecular mechanism of heme oxygenase-1 induction by docosahexaenoic acid in U937 cells.,
Chemico-Biological Interactions, Vol.238, 180-188, 2015.
(DOI: 10.1016/j.cbi.2015.07.005,   PubMed: 26163453,   Elsevier: Scopus)
66. Koichiro Shinoda, Hirofumi Taki, Konen Obayashi, Yukio Ando, Akihiko Watanabe, Akira Komiya, Hideki Fuse, Koichi Tsuneyama and Kazuyuki Tobe :
Wild-type ATTR amyloidosis of the ureter in a 56-year-old woman with rheumatoid arthritis and Sjögren's syndrome.,
International Journal of Clinical and Experimental Pathology, Vol.8, No.7, 8624-8627, 2015.
(PubMed: 26339445)
67. Yin Fan Lam, Ka Kui Tong, Kin Ming Kwan, Koichi Tsuneyama, Shang-An Shu, Patrick S. C. Leung and Ka Hou Chu :
Gastrointestinal Immune Response to the Shrimp Allergen Tropomyosin: Histological and Immunological Analysis in an Animal Model of Shrimp Tropomyosin Hypersensitivity.,
International Archives of Allergy and Immunology, Vol.167, No.1, 29-40, 2015.
(DOI: 10.1159/000431228,   PubMed: 26112225)
68. H Tanaka, G-X Yang, T Tomiyama, Koichi Tsuneyama, W Zhang, P S. C. Leung, R L. Coppel, T Joh, S G. Nadler, A A. Ansari, C Bowlus and M E. Gershwin :
Immunological potential of cytotoxic T lymphocyte antigen 4 immunoglobulin in murine autoimmune cholangitis.,
Clinical and Experimental Immunology, Vol.180, No.3, 371-382, 2015.
(DOI: 10.1111/cei.12581,   PubMed: 25581259)
69. Kei Takahashi, Nao Nagai, Keisuke Ogura, Koichi Tsuneyama, Ikuo Saiki, Tatsuro Irimura and Yoshihiro Hayakawa :
Mammary tissue microenvironment determines T cell-dependent breast cancer-associated inflammation.,
Cancer Science, Vol.106, No.7, 867-874, 2015.
(DOI: 10.1111/cas.12685,   PubMed: 25940224)
70. Takahiko Nakajima, Toshiro Sugiyama, Hayato Baba, Hideki Hatta, Takeshi Nishida, Shigeharu Miwa, Shinichi Hayashi, Koichi Tsuneyama and Johji Imura :
Bone metastasis in gastrointestinal stromal tumors preferentially occurs in patients with original tumors in sites other than the stomach.,
International Journal of Clinical and Experimental Pathology, Vol.8, No.5, 5955-5959, 2015.
(PubMed: 26191327,   Elsevier: Scopus)
71. Akinori Wada, Aya Ito, Hirofumi Iitsuka, Koichi Tsuneyama, Takayoshi Miyazono, Jun Murakami, Naotoshi Shibahara, Hiroaki Sakurai, Ikuo Saiki, Takashi Nakayama, Osamu Yoshie, Keiichi Koizumi and Toshiro Sugiyama :
Role of chemokine CX3CL1 in progression of multiple myeloma via CX3CR1 in bone microenvironments.,
Oncology Reports, Vol.33, No.6, 2935-2939, 2015.
(DOI: 10.3892/or.2015.3941,   PubMed: 25962684)
72. Shohei Takai, Shingo Oda, Koichi Tsuneyama, Tatsuki Fukami, Miki Nakajima and Tsuyoshi Yokoi :
Establishment of a mouse model for amiodarone-induced liver injury and analyses of its hepatotoxic mechanism.,
Journal of Applied Toxicology : JAT, 2015.
(DOI: 10.1002/jat.3141,   PubMed: 25900201)
73. Azumi Iida, Eita Sasaki, Azusa Yano, Koichi Tsuneyama, Tatsuki Fukami, Miki Nakajima and Tsuyoshi Yokoi :
Carbamazepine-Induced Liver Injury Requires CYP3A-Mediated Metabolism and Glutathione Depletion in Rats.,
Drug Metabolism and Disposition, Vol.43, No.7, 958-968, 2015.
(DOI: 10.1124/dmd.115.063370,   PubMed: 25870103)
74. Shinichi Hayashi, Yoshiro Abe, Shigeki Tomita, Yuko Nakanishi, Shigeharu Miwa, Takahiko Nakajima, Kazuhiro Nomoto, Koichi Tsuneyama, Takahiro Fujimori and Johji Imura :
Primary non-gestational pure choriocarcinoma arising in the ovary: A case report and literature review.,
Oncology Letters, Vol.9, No.5, 2109-2111, 2015.
(DOI: 10.3892/ol.2015.2985,   PubMed: 26137022)
75. Fengying Gao, Satoru Yokoyama, Makoto Fujimoto, Koichi Tsuneyama, Ikuo Saiki, Yutaka Shimada and Yoshihiro Hayakawa :
Effect of keishibukuryogan on genetic and dietary obesity models.,
Evidence-Based Complementary and Alternative Medicine : eCAM, Vol.2015, 801291, 2015.
(DOI: 10.1155/2015/801291,   PubMed: 25793003)
76. Masashi Ikutani, Koichi Tsuneyama, Susumu Nakae and Kiyoshi Takatsu :
Emerging roles of IL-33 in inflammation and immune regulation,
Inflammation and Regeneration, Vol.35, No.2, 69-77, 2015.
(DOI: 10.2492/inflammregen.35.069,   CiNii: 130005063944)
77. Ji-Ye Kee, Aya Ito, Shozo Hojo, Isaya Hashimoto, Yoshiko Igarashi, Koichi Tsuneyama, Kazuhiro Tsukada, Tatsuro Irimura, Naotoshi Shibahara, Ichiro Takasaki, Akiko Inujima, Takashi Nakayama, Osamu Yoshie, Hiroaki Sakurai, Ikuo Saiki and Keiichi Koizumi :
CXCL16 suppresses liver metastasis of colorectal cancer by promoting TNF--induced apoptosis by tumor-associated macrophages.,
BMC Cancer, Vol.14, 949, 2014.
(DOI: 10.1186/1471-2407-14-949,   PubMed: 25495942)
78. H Tanaka, W Zhang, G-X Yang, Y Ando, T Tomiyama, Koichi Tsuneyama, P Leung, R L. Coppel, A A. Ansari, Z X. Lian, W M. Ridgway, T Joh and M E. Gershwin :
Successful immunotherapy of autoimmune cholangitis by adoptive transfer of forkhead box protein 3(+) regulatory T cells.,
Clinical and Experimental Immunology, Vol.178, No.2, 253-261, 2014.
(DOI: 10.1111/cei.12415,   PubMed: 25041369)
79. Hiroe Honda, Yoshinori Nagai, Takayuki Matsunaga, Naoki Okamoto, Yasuharu Watanabe, Koichi Tsuneyama, Hiroaki Hayashi, Isao Fujii, Masashi Ikutani, Yoshikatsu Hirai, Atsushi Muraguchi and Kiyoshi Takatsu :
Isoliquiritigenin is a potent inhibitor of NLRP3 inflammasome activation and diet-induced adipose tissue inflammation.,
Journal of Leukocyte Biology, Vol.96, No.6, 1087-1100, 2014.
(DOI: 10.1189/jlb.3A0114-005RR,   PubMed: 25210146)
80. Jun-Ling An, Qiao-Hong Ji, Ji-Jiang An, Shinji Masuda and Koichi Tsuneyama :
Clinicopathological analysis of CD8-positive lymphocytes in the tumor parenchyma and stroma of hepatocellular carcinoma.,
Oncology Letters, Vol.8, No.5, 2284-2290, 2014.
(DOI: 10.3892/ol.2014.2516,   PubMed: 25289108)
81. Koichi Tsuneyama, Takeshi Nishida, Hayato Baba, Shu Taira, Makoto Fujimoto, Kazuhiro Nomoto, Shinichi Hayashi, Shigeharu Miwa, Takahiko Nakajima, Mitsuko Sutoh, Emu Oda, Ryoji Hokao and Johji Imura :
Neonatal monosodium glutamate treatment causes obesity, diabetes, and macrovesicular steatohepatitis with liver nodules in DIAR mice.,
Journal of Gastroenterology and Hepatology, Vol.29, No.9, 1736-1743, 2014.
(DOI: 10.1111/jgh.12610,   PubMed: 24730643)
82. Wei Yang, Yuan Yao, Yan-Qing Yang, Fang-Ting Lu, Liang Li, Yin-Hu Wang, Takahiko Nakajima, Koichi Tsuneyama, William M. Ridgway, M Eric Gershwin and Zhe-Xiong Lian :
Differential modulation by IL-17A of Cholangitis versus Colitis in IL-2R deleted mice.,
PLoS ONE, Vol.9, No.8, e105351, 2014.
(DOI: 10.1371/journal.pone.0105351,   PubMed: 25133396)
83. Jinjun Wang, Guo-Xiang Yang, Koichi Tsuneyama, M Eric Gershwin, William M. Ridgway and Patrick S. C. Leung :
Animal models of primary biliary cirrhosis.,
Seminars in Liver Disease, Vol.34, No.3, 285-296, 2014.
(DOI: 10.1055/s-0034-1383728,   PubMed: 25057952)
84. Hayato Baba, Koichi Tsuneyama, Takeshi Nishida, Hideki Hatta, Takahiko Nakajima, Kazuhiro Nomoto, Shinichi Hayashi, Shigeharu Miwa, Yuko Nakanishi, Ryoji Hokao and Johji Imura :
Neonatal streptozotocin treatment causes type 1 diabetes and subsequent hepatocellular carcinoma in DIAR mice fed a normal diet.,
Hepatology International, Vol.8, No.3, 415-424, 2014.
(DOI: 10.1007/s12072-014-9541-9,   PubMed: 26202643)
85. Mayuko Ichimura, Miku Kawase, Miki Masuzumi, Mika Sakaki, Yasuo Nagata, Kazunari Tanaka, Kazuhito Suruga, Shizuka Tamaru, Shigeko Kato, Koichi Tsuneyama and Katsuhisa Omagari :
High-fat and high-cholesterol diet rapidly induces non-alcoholic steatohepatitis with advanced fibrosis in Sprague-Dawley rats.,
Hepatology Research, Vol.45, No.4, 458-469, 2014.
(DOI: 10.1111/hepr.12358,   PubMed: 24827559)
86. Yu Yamaura, Miki Nakajima, Naoyuki Tatsumi, Shingo Takagi, Tatsuki Fukami, Koichi Tsuneyama and Tsuyoshi Yokoi :
Changes in the expression of miRNAs at the pericentral and periportal regions of the rat liver in response to hepatocellular injury: comparison with the changes in the expression of plasma miRNAs.,
Toxicology, Vol.322, 89-98, 2014.
(DOI: 10.1016/j.tox.2014.05.008,   PubMed: 24863736)
87. Yuki Oda, Miki Nakajima, Koichi Tsuneyama, Masataka Takamiya, Yasuhiro Aoki, Tatsuki Fukami and Tsuyoshi Yokoi :
Retinoid X receptor in human liver is regulated by miR-34a.,
Biochemical Pharmacology, Vol.90, No.2, 179-187, 2014.
(DOI: 10.1016/j.bcp.2014.05.002,   PubMed: 24832862)
88. Makoto Kurano, Masumi Hara, Koichi Tsuneyama, Hideyuki Sakoda, Tomo Shimizu, Kazuhisa Tsukamoto, Hitoshi Ikeda and Yutaka Yatomi :
Induction of insulin secretion by apolipoprotein M, a carrier for sphingosine 1-phosphate.,
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, Vol.1841, No.9, 1217-1226, 2014.
(DOI: 10.1016/j.bbalip.2014.05.002,   PubMed: 24814049)
89. Kazuto Tajiri, Koichi Tsuneyama, Kengo Kawai, Yoshinari Atarashi, Masami Minemura, Shigeaki Sawada, Kazuhiro Tsukada, Johji Imura and Toshiro Sugiyama :
A case of progressing focal nodular hyperplasia and its molecular expression pattern.,
Clinical Journal of Gastroenterology, Vol.7, No.3, 271-277, 2014.
(DOI: 10.1007/s12328-014-0483-5,   PubMed: 26183749)
90. Chen-Yen Yang, Xiong Ma, Koichi Tsuneyama, Shanshan Huang, Toru Takahashi, Naga P. Chalasani, Christopher L. Bowlus, Guo-Xiang Yang, Patrick S. C. Leung, Aftab A. Ansari, Linda Wu, Ross L. Coppel and M Eric Gershwin :
IL-12/Th1 and IL-23/Th17 biliary microenvironment in primary biliary cirrhosis: implications for therapy.,
Hepatology, Vol.59, No.5, 1944-1953, 2014.
(DOI: 10.1002/hep.26979,   PubMed: 24375552)
91. Y-R Deng, K Yoshida, Q L. Jin, M Murata, T Yamaguchi, Koichi Tsuneyama, Y Moritoki, J Q. Niu, K Matsuzaki and Z-X Lian :
Reversible phospho-Smad3 signalling between tumour suppression and fibrocarcinogenesis in chronic hepatitis B infection.,
Clinical and Experimental Immunology, Vol.176, No.1, 102-111, 2014.
(DOI: 10.1111/cei.12259,   PubMed: 24372395)
92. Zheng-Guo Cui, Jin-Lan Piao, Takashi Kondo, Ryohei Ogawa, Koichi Tsuneyama, Qing-Li Zhao, Loreto B. Feril and Hidekuni Inadera :
Molecular mechanisms of hyperthermia-induced apoptosis enhanced by docosahexaenoic acid: implication for cancer therapy.,
Chemico-Biological Interactions, Vol.215, 46-53, 2014.
(DOI: 10.1016/j.cbi.2014.03.005,   PubMed: 24661947)
93. Ryo Okada, Kinzo Matsumoto, Ryohei Tsushima, Hironori Fujiwara and Koichi Tsuneyama :
Social isolation stress-induced fear memory deficit is mediated by down-regulated neuro-signaling system and Egr-1 expression in the brain.,
Neurochemical Research, Vol.39, No.5, 875-882, 2014.
(DOI: 10.1007/s11064-014-1283-5,   PubMed: 24647971)
94. Yuan Yao, Wei Yang, Yan-Qing Yang, Hong-Di Ma, Fang-Ting Lu, Liang Li, Yan-Yan Tao, Koichi Tsuneyama, Weici Zhang, Scott Friedman, M Eric Gershwin and Zhe-Xiong Lian :
Distinct from its canonical effects, deletion of IL-12p40 induces cholangitis and fibrosis in interleukin-2R-/- mice.,
Journal of Autoimmunity, Vol.51, 99-108, 2014.
(DOI: 10.1016/j.jaut.2014.02.009,   PubMed: 24651036)
95. Johji Imura, Shinichi Hayashi, Kazuhito Ichikawa, Shigeharu Miwa, Takahiko Nakajima, Kazuhiro Nomoto, Koichi Tsuneyama, Tatsuya Nogami, Hitoaki Saitoh and Takahiro Fujimori :
Malignant transformation of hyperplastic gastric polyps: An immunohistochemical and pathological study of the changes of neoplastic phenotype.,
Oncology Letters, Vol.7, No.5, 1459-1463, 2014.
(DOI: 10.3892/ol.2014.1932,   PubMed: 24765156)
96. Makoto Fujimoto, Koichi Tsuneyama, Yuko Nakanishi, Thucydides L. Salunga, Kazuhiro Nomoto, Yoshiyuki Sasaki, Seiichi Iizuka, Mitsunobu Nagata, Wataru Suzuki, Tsutomu Shimada, Masaki Aburada, Yutaka Shimada, M Eric Gershwin and Carlo Selmi :
A dietary restriction influences the progression but not the initiation of MSG-Induced nonalcoholic steatohepatitis.,
Journal of Medicinal Food, Vol.17, No.3, 374-383, 2014.
(DOI: 10.1089/jmf.2012.0029,   PubMed: 24588719)
97. Hideki Hatta, Koichi Tsuneyama, Kazuhiro Nomoto, Shinichi Hayashi, Shigeharu Miwa, Takahiko Nakajima, Takeshi Nishida, Yuko Nakanishi and Johji Imura :
A simple and rapid decalcification procedure of skeletal tissues for pathology using an ultrasonic cleaner with D-mannitol and formic acid.,
Acta Histochemica, Vol.116, No.5, 753-757, 2014.
(DOI: 10.1016/j.acthis.2014.01.006,   PubMed: 24560938,   Elsevier: Scopus)
98. J J. Wang, G-X Yang, W C. Zhang, L Lu, Koichi Tsuneyama, M Kronenberg, J L. Véla, M Lopez-Hoyos, X-S He, W M. Ridgway, P S. C. Leung and M E. Gershwin :
Escherichia coli infection induces autoimmune cholangitis and anti-mitochondrial antibodies in non-obese diabetic (NOD).B6 (Idd10/Idd18) mice.,
Clinical and Experimental Immunology, Vol.175, No.2, 192-201, 2014.
(DOI: 10.1111/cei.12224,   PubMed: 24128311)
99. Hayato Baba, Koichi Tsuneyama, Tokimasa Kumada, Keiko Aoshima and Johji Imura :
Histopathological analysis for osteomalacia and tubulopathy in itai-itai disease.,
The Journal of Toxicological Sciences, Vol.39, No.1, 91-96, 2014.
(DOI: 10.2131/jts.39.91,   PubMed: 24418713,   Elsevier: Scopus)
100. Kentaro Kikuchi, Koichi Tsuneyama, Hanae Yamada, Yusuke Kajiyama, Kotaro Matsumoto, Hiromichi Tsunashima, Risa Yamashita, Atsuko Takai, Masatsugu Negishi, Masumi Hara, Yuki Moritoki and Hiroshi Miyakawa :
Splenic lymph follicles generate immunoglobulin M-producing B cells in primary biliary cirrhosis.,
Hepatology Research, Vol.44, No.10, E253-E256, 2014.
(DOI: 10.1111/hepr.12231,   PubMed: 24033874)
101. Katsuhisa Omagari, Chisato Yoshikawa, Shin-ichi Inoue, Yuna Tanaka, Toshie Murayama, Mayuko Ichimura, Ayako Miyata, Sawako Mori, Mai Kamogawa, Eri Hirao, Shigeko Kato, Kazuhito Suruga and Koichi Tsuneyama :
Abdominal subcutaneous adipose tissue accumulation is positively correlated with hepatic steatosis in Sprague-Dawley rats,
Acta Medica Nagasakiensia, Vol.59, No.2, 47-56, 2014.
(DOI: 10.11343/amn.59.47,   CiNii: 130004879533,   Elsevier: Scopus)
102. Johji Imura, Kaori Abe, Yoshiaki Uchida, Masaharu Shibata, Kazue Tsunematsu, Motohiro Sathoh, Shigeharu Miwa, Takahiko Nakajima, Kazuhiro Nomoto, Shinichi Hayashi and Koichi Tsuneyama :
Introduction and utility of liquid-based cytology on aspiration biopsy of peripheral nodular lesions of the lung.,
Oncology Letters, Vol.7, No.3, 669-673, 2013.
(DOI: 10.3892/ol.2013.1763,   PubMed: 24520290)
103. H Tanaka, G-X Yang, N Iwakoshi, S J. Knechtle, K Kawata, Koichi Tsuneyama, P Leung, R L. Coppel, A A. Ansari, T Joh, C Bowlus and M E. Gershwin :
Anti-CD40 ligand monoclonal antibody delays the progression of murine autoimmune cholangitis.,
Clinical and Experimental Immunology, Vol.174, No.3, 364-371, 2013.
(DOI: 10.1111/cei.12193,   PubMed: 23981074)
104. Kentaro Matsuo, Eita Sasaki, Satonori Higuchi, Shohei Takai, Koichi Tsuneyama, Tatsuki Fukami, Miki Nakajima and Tsuyoshi Yokoi :
Involvement of oxidative stress and immune- and inflammation-related factors in azathioprine-induced liver injury.,
Toxicology Letters, Vol.224, No.2, 215-224, 2013.
(DOI: 10.1016/j.toxlet.2013.10.025,   PubMed: 24184165)
105. Xiao-Yu Luo, Terumi Takahara, Kengo Kawai, Masayuki Fujino, Toshiro Sugiyama, Koichi Tsuneyama, Kazuhiro Tsukada, Susumu Nakae, Liang Zhong and Xiao-Kang Li :
IFN- deficiency attenuates hepatic inflammation and fibrosis in a steatohepatitis model induced by a methionine- and choline-deficient high-fat diet.,
American Journal of Physiology, Gastrointestinal and Liver Physiology, Vol.305, No.12, G891-9, 2013.
(DOI: 10.1152/ajpgi.00193.2013,   PubMed: 24136786)
106. Kazuhito Kawata, Masanobu Tsuda, Guo-Xiang Yang, Weici Zhang, Hajime Tanaka, Koichi Tsuneyama, Patrick Leung, Xiao-Song He, Stuart Knechtle, Aftab A. Ansari, Ross L. Coppel and M Eric Gershwin :
Identification of potential cytokine pathways for therapeutic intervention in murine primary biliary cirrhosis.,
PLoS ONE, Vol.8, No.9, e74225, 2013.
(DOI: 10.1371/journal.pone.0074225,   PubMed: 24040208)
107. Eita Sasaki, Kentaro Matsuo, Azumi Iida, Koichi Tsuneyama, Tatsuki Fukami, Miki Nakajima and Tsuyoshi Yokoi :
A novel mouse model for phenytoin-induced liver injury: involvement of immune-related factors and P450-mediated metabolism.,
Toxicological Sciences, Vol.136, No.1, 250-263, 2013.
(DOI: 10.1093/toxsci/kft184,   PubMed: 23986454)
108. Yan-Ru Deng, Hong-Di Ma, Koichi Tsuneyama, Wei Yang, Yin-Hu Wang, Fang-Ting Lu, Cheng-Hai Liu, Ping Liu, Xiao-Song He, Anna Mae Diehl, M Eric Gershwin and Zhe-Xiong Lian :
STAT3-mediated attenuation of CCl4-induced mouse liver fibrosis by the protein kinase inhibitor sorafenib.,
Journal of Autoimmunity, Vol.46, 25-34, 2013.
(DOI: 10.1016/j.jaut.2013.07.008,   PubMed: 23948302)
109. Cheng-Pu Sun, Tzu-Hui Wu, Chun-Chi Chen, Ping-Yi Wu, Yao-Ming Shih, Koichi Tsuneyama and Mi-Hua Tao :
Studies of efficacy and liver toxicity related to adeno-associated virus-mediated RNA interference.,
Human Gene Therapy, Vol.24, No.8, 739-750, 2013.
(DOI: 10.1089/hum.2012.239,   PubMed: 23829557)
110. Koichi Tsuneyama, Hayato Baba, Kentaro Kikuchi, Takeshi Nishida, Kazuhiro Nomoto, Shinichi Hayashi, Shigeharu Miwa, Takahiko Nakajima, Yuko Nakanishi, Shinji Masuda, Mitsuhiro Terada, Johji Imura and Carlo Selmi :
Autoimmune features in metabolic liver disease: a single-center experience and review of the literature.,
Clinical Reviews in Allergy & Immunology, Vol.45, No.1, 143-148, 2013.
(DOI: 10.1007/s12016-013-8383-x,   PubMed: 23842720)
111. Kazuhito Kawata, Guo-Xiang Yang, Yugo Ando, Hajime Tanaka, Weici Zhang, Yoshimasa Kobayashi, Koichi Tsuneyama, Patrick S. C. Leung, Zhe-Xiong Lian, William M. Ridgway, Aftab A. Ansari, Xiao-Song He and M Eric Gershwin :
Clonality, activated antigen-specific CD8(+) T cells, and development of autoimmune cholangitis in dnTGFRII mice.,
Hepatology, Vol.58, No.3, 1094-1104, 2013.
(DOI: 10.1002/hep.26418,   PubMed: 23532950)
112. Kazuto Tajiri, Koichi Tsuneyama, Takahiro Miyazono, Kengo Kawai, Masami Minemura and Toshiro Sugiyama :
A case of primary biliary cirrhosis that progressed rapidly after treatment involving rituximab.,
Case Reports in Gastroenterology, Vol.7, No.1, 195-201, 2013.
(DOI: 10.1159/000351173,   PubMed: 23687488)
113. Mayuko Ichimura, Shigeko Kato, Koichi Tsuneyama, Sachiko Matsutake, Mai Kamogawa, Eri Hirao, Ayako Miyata, Sawako Mori, Noriaki Yamaguchi, Kazuhito Suruga and Katsuhisa Omagari :
Phycocyanin prevents hypertension and low serum adiponectin level in a rat model of metabolic syndrome.,
Nutrition Research, Vol.33, No.5, 397-405, 2013.
(DOI: 10.1016/j.nutres.2013.03.006,   PubMed: 23684441)
114. Hayato Baba, Koichi Tsuneyama, Megumi Yazaki, Kohei Nagata, Takashi Minamisaka, Tatsuhiro Tsuda, Kazuhiro Nomoto, Shinichi Hayashi, Shigeharu Miwa, Takahiko Nakajima, Yuko Nakanishi, Keiko Aoshima and Johji Imura :
The liver in itai-itai disease (chronic cadmium poisoning): pathological features and metallothionein expression.,
Modern Pathology, Vol.26, No.9, 1228-1234, 2013.
(DOI: 10.1038/modpathol.2013.62,   PubMed: 23558578)
115. S Fujisaka, I Usui, M Ikutani, A Aminuddin, A Takikawa, Koichi Tsuneyama, A Mahmood, N Goda, Y Nagai, K Takatsu and K Tobe :
Adipose tissue hypoxia induces inflammatory M1 polarity of macrophages in an HIF-1-dependent and HIF-1-independent manner in obese mice.,
Diabetologia, Vol.56, No.6, 1403-1412, 2013.
(DOI: 10.1007/s00125-013-2885-1,   PubMed: 23494472)
116. Takashi Yamaguchi, Koichi Matsuzaki, Ryosuke Inokuchi, Rinako Kawamura, Katsunori Yoshida, Miki Murata, Junichi Fujisawa, Nobuyoshi Fukushima, Michio Sata, Masayoshi Kage, Osamu Nakashima, Akihiro Tamori, Norifumi Kawada, Koichi Tsuneyama, Steven Dooley, Toshihito Seki and Kazuichi Okazaki :
Phosphorylated Smad2 and Smad3 signaling: Shifting between tumor suppression and fibro-carcinogenesis in chronic hepatitis C.,
Hepatology Research, Vol.43, No.12, 1327-1342, 2013.
(DOI: 10.1111/hepr.12082,   PubMed: 23458062)
117. Dong Han, Yasuhiko Yamamoto, Seiichi Munesue, So Motoyoshi, Hidehito Saito, Myat Thu Thu Win, Takuo Watanabe, Koichi Tsuneyama and Hiroshi Yamamoto :
Induction of receptor for advanced glycation end products by insufficient leptin action triggers pancreatic -cell failure in type 2 diabetes.,
Genes to Cells, Vol.18, No.4, 302-314, 2013.
(DOI: 10.1111/gtc.12036,   PubMed: 23410183)
118. Amy Dhirapong, Guo-Xiang Yang, Steven Nadler, Weici Zhang, Koichi Tsuneyama, Patrick Leung, Stuart Knechtle, Aftab A. Ansari, Ross L. Coppel, Fu-Tong Liu, Xiao-Song He and M Eric Gershwin :
Therapeutic effect of cytotoxic T lymphocyte antigen 4/immunoglobulin on a murine model of primary biliary cirrhosis.,
Hepatology, Vol.57, No.2, 708-715, 2013.
(DOI: 10.1002/hep.26067,   PubMed: 22996325)
119. Shiro Watanabe and Koichi Tsuneyama :
Eicosapentaenoic acid attenuates hepatic accumulation of cholesterol esters but aggravates liver injury and inflammation in mice fed a cholate-supplemented high-fat diet.,
The Journal of Toxicological Sciences, Vol.38, No.3, 379-390, 2013.
(DOI: 10.2131/jts.38.379,   PubMed: 23665937)
120. Masahisa Arahata, Kazuto Tajiri, Kazuhiro Nomoto, Koichi Tsuneyama, Shinji Minami and Yukihiro Shimizu :
A novel type of selective immunoglobulin m deficiency in a patient with autoimmune liver cirrhosis with recurrent hepatocellular carcinoma: a case report and review of the literature.,
International Archives of Allergy and Immunology, Vol.161, No.1, 91-96, 2012.
(DOI: 10.1159/000343583,   PubMed: 23257944)
121. Chikako Inada, Xoan Le Thi, Koichi Tsuneyama, Hironori Fujiwara, Takeshi Miyata and Kinzo Matsumoto :
Endogenous acetylcholine rescues NMDA-induced long-lasting hippocampal cell damage via stimulation of muscarinic M(1) receptors: elucidation using organic hippocampal slice cultures.,
European Journal of Pharmacology, Vol.699, No.1-3, 150-159, 2012.
(DOI: 10.1016/j.ejphar.2012.11.061,   PubMed: 23220711)
122. Takeshi Nishida, Koichi Tsuneyama, Makoto Fujimoto, Kazuhiro Nomoto, Shinichi Hayashi, Shigeharu Miwa, Takahiko Nakajima, Yuko Nakanishi, Yoshiyuki Sasaki, Wataru Suzuki, Seiichi Iizuka, Mitsunobu Nagata, Tsutomu Shimada, Masaki Aburada, Yutaka Shimada and Johji Imura :
Spontaneous onset of nonalcoholic steatohepatitis and hepatocellular carcinoma in a mouse model of metabolic syndrome.,
Laboratory Investigation; a Journal of Technical Methods and Pathology, Vol.93, No.2, 230-241, 2012.
(DOI: 10.1038/labinvest.2012.155,   PubMed: 23212097)
123. Motoko Sasaki, Takashi Matsubara, Norihide Yoneda, Kazuhiro Nomoto, Koichi Tsuneyama, Yasunori Sato and Yasuni Nakanuma :
Overexpression of enhancer of zeste homolog 2 and MUC1 may be related to malignant behaviour in intraductal papillary neoplasm of the bile duct.,
Histopathology, Vol.62, No.3, 446-457, 2012.
(DOI: 10.1111/his.12016,   PubMed: 23163606)
124. Yasuharu Watanabe, Tomoya Nakamura, Sho Ishikawa, Shiho Fujisaka, Isao Usui, Koichi Tsuneyama, Yoshinori Ichihara, Tsutomu Wada, Yoichiro Hirata, Takayoshi Suganami, Hirofumi Izaki, Shizuo Akira, Kensuke Miyake, Hiro-omi Kanayama, Michio Shimabukuro, Masataka Sata, Toshiyasu Sasaoka, Yoshihiro Ogawa, Kazuyuki Tobe, Kiyoshi Takatsu and Yoshinori Nagai :
The Radioprotective 105/MD-1 complex contributes to diet-induced obesity and adipose tissue inflammation.,
Diabetes, Vol.61, No.5, 1199-1209, 2012.
(DOI: 10.2337/db11-1182,   PubMed: 22396206,   Elsevier: Scopus)
125. Shu Taira, Shuichi Shimma, Issey Osaka, Daisaku Kaneko, Yuko Ichiyanagi, Ryuzo Ikeda, Yasuko Konishi-Kawamura, Shu Zhu, Koichi Tsuneyama and Katsuko Komatsu :
Mass spectrometry imaging of the capsaicin localization in the capsicum fruits,
International Journal of Biotechnology for Wellness Industries, Vol.1, No.1, 61-65, 2012.
(DOI: 10.6000/1927-3037.2012.01.01.04,   CiNii: 120004247365)
126. Shiho Fujisaka, Isao Usui, Agussalim Bukhari, Masashi Ikutani, Takeshi Oya, Yukiko Kanatani, Koichi Tsuneyama, Yoshinori Nagai, Kiyoshi Takatsu, Masaharu Urakaze, Masashi Kobayashi and Kazuyuki Tobe :
Regulatory mechanisms for adipose tissue M1 and M2 macrophages in diet-induced obese mice.,
Diabetes, Vol.58, No.11, 2574-2582, 2009.
(DOI: 10.2337/db08-1475,   PubMed: 19690061)
127. Hikari Suzuki, Ichiro Kato, Isao Usui, Ichiro Takasaki, Yoshiaki Tabuchi, Takeshi Oya, Koichi Tsuneyama, Hiroshi Kawaguchi, Koichi Hiraga, Shin Takasawa, Hiroshi Okamoto, Kazuyuki Tobe and Masakiyo Sasahara :
Characterization of diabetic nephropathy in CaM kinase IIalpha (Thr286Asp) transgenic mice.,
Biochemical and Biophysical Research Communications, Vol.379, No.1, 38-42, 2008.
(DOI: 10.1016/j.bbrc.2008.11.143,   PubMed: 19070598)
128. Chunmei Cheng, Koichi Tsuneyama, Huachuan Zheng, Takeshi Oya, Zhengguo Cui, B Loreto Feril and Yasuo Takano :
Enhanced scavenging of lipid substances is a possible effect of corticosteroids in the treatment of cholesterol crystal embolism.,
Pathology, Research and Practice, Vol.202, No.8, 591-598, 2006.
(DOI: 10.1016/j.prp.2006.04.005,   PubMed: 16814943)

Academic Paper (Unrefereed Paper):

1. Koichi Tsuneyama, Baba Hayato and Nishida Takeshi :
メタボリックシンドロームモデルマウスを用いた,マウス頻回肝生検法の開発,
Proceedings of the Japanese Society of Pathology, Vol.104, No.1, 378,
2. Azumi IIDA, azusa YANO, Koichi Tsuneyama, Tatsuki FUKAMI, Miki NAKAJIMA and Tsuyoshi YOKOI :
Involvement of metabolic activation of carbamazepine in liver injury in rat,
Annual Meeting of the Japanese Society of Toxicology, Vol.40, No.0, 1003038, 2013.
(DOI: 10.14869/toxpt.40.1.0.1003038.0,   CiNii: 130004676518)

Academic Letter:

1. Tamehito Onoe, Tadashi Konoshita, Koichi Tsuneyama, Ryoko Hamano, Ichiro Mizushima, Yasushi Kakuchi, Kazunori Yamada, Kenshi Hayashi, Masahiro Kuroda, Satoshi Kagitani, Hideki Nomura, Masakazu Yamagishi and Mitsuhiro Kawano :
Situs inversus and cystic kidney disease: Two adult patients with this Heterogeneous syndrome.,
The American Journal of Case Reports, Vol.14, 20-25, 2013.
(DOI: 10.12659/AJCR.883751,   PubMed: 23569556)

Review, Commentary:

1. Minoru Matsumoto, Hitoshi Nishijima, Junko Morimoto, Koichi Tsuneyama and Mitsuru Matsumoto :
AIRE - The Autoimmune Regulator,
eLS, Feb. 2019.
(DOI: 10.1002/9780470015902.a0027281)
2. Minoru Matsumoto, Koichi Tsuneyama and Mitsuru Matsumoto :
AIRE遺伝子と多腺性自己免疫症候群,
The Medical Frontline, Vol.73, No.5, 688-692, May 2018.
3. Koichi Tsuneyama :
非アルコール性脂肪性肝障害(NAFLD)/肝炎(NASH)の肝生検診断の注意点,
診断病理, Vol.34, No.3, 143-151, Jul. 2017.
4. Koichi Tsuneyama :
New animal models for the translational study of metabolic syndrome-associated liver diseases,
Shikoku Acta Medica, Vol.71, No.5,6, 113-120, Dec. 2015.
(Tokushima University Institutional Repository: 109934,   CiNii: 120005851763)
5. 佐々塚 涼弥, 馬場 逸人, 菊池 健太郎, 守時 由起 and Koichi Tsuneyama :
原発性胆汁性肝硬変の免疫病理,
肝胆膵, Vol.71, No.5, 831-837, Nov. 2015.

Proceeding of International Conference:

1. Mitsuru Matsumoto, Junko Morimoto, Minoru Matsumoto, Koichi Tsuneyama, Ryuichiro Miyazawa and Hitoshi Nishijima :
Aire-dependent establishment of self-tolerance studied by genetically modified mice,
EMBO Workshop ThymE, Israel, May 2019.
2. Koichi Tsuneyama :
Pathological features of new animal models for primary biliary cholangitis,
Eric Gershwin symposium, Tokyo Universitu, Tokyo, Feb. 2019.
3. Koichi Tsuneyama :
Novel animal models for analyzing metabolic syndrome-associated liver diseases,
2nd SCUT international symposium of liver imunology, Feb. 2019.
4. Koichi Tsuneyama :
Novel diet-induced NASH midel showing severe liver fibrosis,
Monthly meetng, Novonordisk in Beijing, Jan. 2019.
5. Koichi Tsuneyama :
Elucidating the mechanism of fibrogenesis and carcinogenesis in NASH,
Annual meeting of Pharmaceutical labs, the Seoul National University, Dec. 2018.
6. Mitsuru Matsumoto, Minoru Matsumoto, Junko Morimoto, Koichi Tsuneyama and Hitoshi Nishijima :
Tissue-specific autoimmunity manipulated by Aire in thymic and peripheral tolerance,
Immunology of Diabetes Society Congress 2018, London, Oct. 2018.
7. Koichi Tsuneyama :
Comparative Pathology of Murine Model of PBC,
Lugano meeting of PBC, Sep. 2018.
8. Minoru Matsumoto, Hitoshi Nishijima, Junko Morimoto, Koichi Tsuneyama and Mitsuru Matsumoto :
Manipulation of thymic and peripheral tolerance by AIRE defines distinct tissue-specific autoimmunity,
11th International Congress on Autoimmunity, Lisbon, Portugal, May 2018.
9. Mitsuru Matsumoto, Junko Morimoto, Minoru Matsumoto, Koichi Tsuneyama and Hitoshi Nishijima :
A novel Aire-dependent subset of mTECs with tolerogenic functions is defined by Ly6 family protein expression,
ThymOz8, Heron Island, Australia, Mar. 2018.
10. Minoru Matsumoto, Hitoshi Nishijima, Junko Morimoto, Koichi Tsuneyama and Mitsuru Matsumoto :
Acquisition of the resistance to autoimmune diabetes by the expression of human AIRE in BM-derived APCs in NOD,
ThymOz8, Heron Island, Australia, Mar. 2018.
11. Koichi Tsuneyama :
Pathological & Immunological characters of animal models for analyzing metabolic syndrome-associated liver disease,
International conference of immunological liver diseases in SCTU, Mar. 2018.
12. Ayumi Sugitani, Mayuko Ichimura, Shu Taira, Takaaki Tsunematsu and Koichi Tsuneyama :
Analysis of fibrogenic roles of liver infiltrating macrophages in a novel Non-alcoholic steatohepatitis (NASH) rat model with liver cirrhosis,
Hepatology, Vol.66, No.S1, 1099A-1100A, Oct. 2017.
13. Kazuchika Nishitsuji, Inoue Koichi, Akatsu Hiroyasu and Koichi Tsuneyama :
Gut dysbiosis and altered plasma short chain fatty acid profile underlie the pathogenesis of nonalcoholic steatohepatitis,
Hepatology, Vol.66, No.S1, 450A, Oct. 2017.
14. Kaizo Kagemoto, Koichi Okamoto, Tohshi Takaoka, Yasuyuki Okada, Kumiko Tanaka, Akihiro Hirao, Shinji Kitamura, Tetsuo Kimura, Hiroshi Miyamoto, Naoki Muguruma, Toshiya Okahisa, Koichi Tsuneyama and Tetsuji Takayama :
Detection of Aberrant Crypt Foci Using Image-Enhanced Endoscopy.,
Digestive Disease Week2017, Chicago, May 2017.
15. Shota Fujimoto, Naoki Muguruma, Koichi Okamoto, Misaki Miwa, Yoshihiko Miyamoto, Yoshifumi Takaoka, Koichi Tsuneyama and Tetsuji Takayama :
A New Theranostic Combination of Fluorescent Molecular Imaging and Laser Therapy Targeting C-Kit in Gastrointestinal Stromal Tumors.,
Digestive Disease Week2017, Chicago, May 2017.
16. Koichi Tsuneyama, Ryosuke Bessho, Masahiro Miki, Hayato Baba, Tetsuyuki Takahashi, Hirohisa Ogawa and Hisanori Uehara :
Hyperinsulinemia, not hyperglycemia accelerates the progression of hepatocellular carcinoma in neonatal streptozotocin induced mouse model,
Annual meeting, American Association for the study of the Liver, Nov. 2015.
17. Koichi Tsuneyama, Hayato Baba, Takeshi Nishida and Johji Imura :
Daily moderate coffee intake inhibits pancreatic beta-cell damage and nonalcoholic steatohepatitis without improving obesity in a mouse model of spontaneous metabolic syndrome.,
24th Conference of the Asian Pacific Associaton for the Study of the Liver (APASL ). 3/ 12 - 15, 2015, Istanbul, Turke, Mar. 2015.

Proceeding of Domestic Conference:

1. Takeshi Oya, Minoru Matsumoto, Noriko Kagawa, Michiko Yamashita, Hirohisa Ogawa and Koichi Tsuneyama :
小腸腫瘍の1例,
日本病理学会中国四国支部学術集会 第130回スライドカンファレンス, Oct. 2019.
2. Mayuko Ichimura, 大曲 勝久 and Koichi Tsuneyama :
食餌摂取による高度な線維化を伴うNASHモデルマウスの開発,
第55回日本肝臓学会総会, May 2019.
3. Koichi Tsuneyama :
免疫チェックポイント阻害薬による肝障害をきたした4例の病理学的特徴,
日本肝臓学会総会, May 2019.
4. Koichi Tsuneyama and Mayuko Ichimura :
免疫チェックポイント阻害薬による肝障害を来した4例の病理学的特徴,
第55回日本肝臓学会総会, May 2019.
5. 飯田 綾香, 甲斐 瑠衣子, 倉貫 早智, Mayuko Ichimura, Koichi Tsuneyama and 中村 強 :
Nonalcoholic fatty liver Disease in Western Diet-Loaded C57BL/6J mice,
第73回日本栄養食糧学会大会, May 2019.
6. 福田 歩美, 佐々尾 真鈴, 浅川 惠理, 成田 純令, 久野 萌偉, 駿河 和仁, Mayuko Ichimura, Koichi Tsuneyama, 田中 一成 and 大曲 勝久 :
Incidence of non-alcoholic steatohepatitis in SD rats fed a high-fat and high-cholesterol diet.,
第73回日本栄養食糧学会大会, May 2019.
7. Mayuko Ichimura, 大曲 勝久 and Koichi Tsuneyama :
Establishment of dietary model of nonalcoholic steatohepatitis-related fibrosis,
第73回日本栄養食糧学会大会, May 2019.
8. Mayuko Ichimura, Takeshi Oya, Hirohisa Ogawa, 大曲 勝久 and Koichi Tsuneyama :
Cholesterol-loaded macrophage is associated with development of hepatic fibrosis in mice,
第108回日本病理学会総会, May 2019.
9. Koichi Tsuneyama :
NASH周辺・関連疾患の病理,
日本病理学会総会, May 2019.
10. Koichi Tsuneyama :
慢性肝疾患病理診断のpitfall,
-, Mar. 2019.
11. Miwa Kubo, Shunsuke Watanabe, Michiko Yamashita, Takeshi Oya and Koichi Tsuneyama :
子宮頸部病変,
日本病理学会中国四国支部学術集会 第128回スライドカンファレンス, Feb. 2019.
12. Takeshi Oya, Minoru Matsumoto, Hirohisa Ogawa and Koichi Tsuneyama :
胃病変,
日本病理学会中国四国支部学術集会 第128回スライドカンファレンス, Feb. 2019.
13. Jinsei Miyoshi, 村山 典聡, Tadahiko Nakagawa, Koichi Okamoto, Yasushi Sato, Naoki Muguruma, Kensei Nishida, Koichi Tsuneyama, 藤盛 孝博 and Tetsuji Takayama :
直腸NETのmiRNA-Gene-Pathwayを介した転移機序の解明とmiR-144-3p/451aの転移予測マーカーとしての意義.,
第15回日本消化管学会総会学術集会, Feb. 2019.
14. Koichi Tsuneyama :
肝腫瘍の病理学的特徴と鑑別診断,
和歌山悪性腫瘍研究会, Dec. 2018.
15. Shoko Iwahashi, Hideya Kashihara, Chie Takasu, Masaaki Nishi, Takuya Tokunaga, Tomohiko Miyatani, Jun Higashijima, Kouzou Yoshikawa, Koichi Tsuneyama and Mitsuo Shimada :
Osteoclast-like giant cellを伴うhamartomatous inverted polypから発生したリンパ球浸潤胃癌の一例,
第29回日本消化器癌発生学会総会, Nov. 2018.
16. Koichi Tsuneyama, Mayuko Ichimura, Takeshi Oya, Minoru Matsumoto and Hirohisa Ogawa :
異なる系統で作成したストレプトゾトシン誘導肝細胞癌モデルマウスの病態比較,
第29回日本消化器癌発生学会総会, Nov. 2018.
17. Hiroyoshi Watanabe, Kazumi Okamura, 大隅 敬太, 市原 裕子, 森本 友樹, Koichi Tsuneyama and Shoji Kagami :
治療抵抗性の悪性骨軟部腫瘍に対するPazopanibの使用経験~免疫組織化学染色による検討~,
第60回日本小児血液・がん学会, Nov. 2018.
18. Shota Fujimoto, Naoki Muguruma, Koichi Okamoto, Yasushi Sato, Yoshihiko Miyamoto, Michiyasu Nakao, Shinji Kitamura, Hiroshi Miyamoto, Shigeki Sano, Tatsuhiro Ishida, Koichi Tsuneyama and Tetsuji Takayama :
Theranostics理論に基づく消化管間質腫瘍(GIST)の新規診断治療法の開発.,
第26回日本消化器関連学会週間(第96回日本消化器内視鏡学会総会), Nov. 2018.
19. Yuki Morimoto, Hirohisa Ogawa, Takeshi Oya and Koichi Tsuneyama :
液状化検体細胞診における迅速質量分析の有用性,
日本臨床細胞学会雑誌, Vol.57, No.Suppl.2, 585, Oct. 2018.
20. Koichi Tsuneyama :
肝臓病理所見のとり方とその解釈,
日本法医病理学会, Sep. 2018.
21. Koichi Tsuneyama :
肝生検診断の実際とNAFLDの病理診断の動向,
徳島肝疾患病理研究会, Aug. 2018.
22. Mayuko Ichimura, Kazuchika Nishitsuji, 清水 金忠, Hirohisa Ogawa, Takaaki Tsunematsu, 梅本 ひとみ, 森本 友樹, 赤津 裕康, 井之上 浩一 and Koichi Tsuneyama :
TSODマウスにおけるNAFLDの発症およびコーヒーの投与による腸内細菌叢および短鎖脂肪酸プロファイルの変化,
第5回肝臓と糖尿病・代謝研究会, Jul. 2018.
23. Shinichiro Yamada, Yu Saitou, Shuichi Iwahashi, Tetsuya Ikemoto, Satoru Imura, Yuji Morine, Koichi Tsuneyama and Mitsuo Shimada :
症例,
第54回日本肝癌研究会, Jun. 2018.
24. Shoko Iwahashi, Yu Saitou, Yuji Morine, Satoru Imura, Tetsuya Ikemoto, Shuichi Iwahashi, Hiroki Teraoku, Mitsuo Shimada and Koichi Tsuneyama :
自然退縮を認めたInflammatory hepatocellular adenomaの一例,
第109回日本消化器病学会四国支部例会, Jun. 2018.
25. Mayuko Ichimura, 大曲 勝久 and Koichi Tsuneyama :
The morphological changes of the liver of TSOD and TSNO mice fed the high-fat plus cholesterol diet,
第107回日本病理学会総会, Jun. 2018.
26. Koichi Tsuneyama :
NAFLDの病理診断の動向,
日本超音波医学会学術集会, Jun. 2018.
27. Makoto Tobiume, Hirokazu Ogino, Afroj Tania, Hisatsugu Goto, Hiroshi Nokihara, Mitsuteru Yoshida, Yukikiyo Kawakami, Hiromitsu Takizawa, Hirohisa Ogawa, Koichi Tsuneyama and Yasuhiko Nishioka :
上皮間葉転換 (EMT)が肺多形癌の悪性化に寄与する可能性についての検討.,
第58回日本呼吸器学会学術講演会, Apr. 2018.
28. 宮崎 克己, Yu Saitou, Yuji Morine, Satoru Imura, Tetsuya Ikemoto, Shuichi Iwahashi, Hiroki Teraoku, Koichi Tsuneyama and Mitsuo Shimada :
自然退縮を認めたInflammatory hepatocellular adenomaの一例,
第118回日本外科学会定期学術集会, Apr. 2018.
29. Koichi Tsuneyama :
消化管疾患における病理の基本,
消化器内視鏡学会四国セミナー, Jan. 2018.
30. Minoru Matsumoto, Hitoshi Nishijima, Junko Morimoto, Koichi Tsuneyama and Mitsuru Matsumoto :
Transgenic human AIRE expression in NOD acquired resistance to the diabetes due to the impaired presentation of self-antigens in the pancreas,
第46回日本免疫学会学術集会, Dec. 2017.
31. 村山 典聡, Koichi Okamoto, Tadahiko Nakagawa, Tetsuo Kimura, Tatsuya Taniguchi, Hironori Tanaka, Yasushi Sato, Naoki Muguruma, Koichi Tsuneyama, 藤盛 孝博 and Tetsuji Takayama :
miR-144-3p/miR-451a はPTEN/p19 を抑制することにより直腸カルチノイド(NET-G1)の浸潤・転移に関与する.,
第76回日本癌学会学術総会, Sep. 2017.
32. Hiroki Teraoku, Tetsuya Ikemoto, Yuuma Wada, Shogo Oota, Yu Saitou, Shuichi Iwahashi, Satoru Imura, Yuji Morine, Mitsuo Shimada and Koichi Tsuneyama :
単純性嚢胞との鑑別に苦慮したnonmucinous cyctadenoma の1例,
第67回日本消化器画像診断研究会, Sep. 2017.
33. Hiroki Teraoku, Mitsuo Shimada, Yuji Morine, Satoru Imura, Tetsuya Ikemoto, Shuichi Iwahashi, Yu Saitou, Masato Yoshikawa, Toshiaki Yoshimoto, Atsushi Takata and Koichi Tsuneyama :
症例,
第53回日本肝癌研究会, Jul. 2017.
34. Shoko Iwahashi, Tetsuya Ikemoto, Mitsuo Shimada, Masato Yoshikawa, Hiroki Teraoku, Yu Saitou, Shuichi Iwahashi, Satoru Imura, Yuji Morine and Koichi Tsuneyama :
単純性嚢胞との鑑別に苦慮した極めて稀な膵嚢胞の1例,
第42回日本外科系連合学会学術集会, Jun. 2017.
35. 宮崎 克己, Yu Saitou, Yuji Morine, Koichi Tsuneyama, Satoru Imura, Tetsuya Ikemoto, Shuichi Iwahashi, Masato Yoshikawa, Toshiaki Yoshimoto, Atsushi Takata and Mitsuo Shimada :
限局性結節性過形成(FNH)術後に再発増殖し肝不全で死亡した一例,
第117回日本外科学会定期学術集会, Apr. 2017.
36. Takaaki Tsunematsu, Yasusei Kudo, Akiko Yamada, Rieko Arakaki, Hirohisa Ogawa, Koichi Tsuneyama and Naozumi Ishimaru :
胎児性癌細胞におけるユビキチンプロテアソーム経路による未分化性維持機構,
第106回日本病理学会総会, Vol.106, Apr. 2017.
37. 菊池 健太郎, Koichi Tsuneyama, Mayuko Ichimura, 守時 由起, 松本 光太郎, 綱島 弘道, 大曲 勝久, 安田 一朗, 原 眞純 and 宮川 浩 :
monosodium glutamate投与によるNASHモデルマウスに対するフラクトオリゴ糖の効果,
Acta Hepatologica Japonica, Vol.58, No.Suppl.1, A388, Apr. 2017.
38. Mayuko Ichimura, Koichi Tsuneyama, 守時 由起, 松本 光太郎, 綱島 弘道, 大曲 勝久 and 菊池 健太郎 :
異なる非アルコール性脂肪肝炎モデル間におけるフラクトオリゴ糖による肝脂肪化抑制機序の違い,
Acta Hepatologica Japonica, Vol.58, No.Suppl.1, A395, Apr. 2017.
39. Koichi Tsuneyama, Mayuko Ichimura and 大曲 勝久 :
食餌誘導NASH 肝線維化モデルラットにおける肝浸潤マクロファージの性状,
Acta Hepatologica Japonica, Vol.58, No.Suppl.1, A396, Apr. 2017.
40. 筒井 朱美, Koichi Tsuneyama, 馬場 伸介, 妹尾 知典, 永野 拓也 and 高口 浩一 :
自己免疫性肝炎と薬物性肝障害に対する臨床病理学的検討,
Acta Hepatologica Japonica, Vol.58, No.Suppl.1, A265, Apr. 2017.
41. 菊池 健太郎, Koichi Tsuneyama, 市村 真祐子, 守時 由起, 松本 光太郎, 綱島 弘道, 大曲 勝久, 安田 一朗, 原 眞純 and 宮川 浩 :
monosodium glutamate投与によるNASHモデルマウスに対するフラクトオリゴ糖の効果,
Acta Hepatologica Japonica, Vol.58, No.Suppl.1, A388, Apr. 2017.
42. 市村 真祐子, Koichi Tsuneyama, 守時 由起, 松本 光太郎, 綱島 弘道, 大曲 勝久 and 菊池 健太郎 :
異なる非アルコール性脂肪肝炎モデル間におけるフラクトオリゴ糖による肝脂肪化抑制機序の違い,
Acta Hepatologica Japonica, Vol.58, No.Suppl.1, A395, Apr. 2017.
43. Koichi Tsuneyama, 市村 真祐子 and 大曲 勝久 :
食餌誘導NASH 肝線維化モデルラットにおける肝浸潤マクロファージの性状,
Acta Hepatologica Japonica, Vol.58, No.Suppl.1, A396, Apr. 2017.
44. 東 泰孝 and Koichi Tsuneyama :
インターロイキン-19はコリン欠乏メチオニン含有高脂肪コレステロール添加食による肝線維過形成に関与する,
Acta Hepatologica Japonica, Vol.58, No.Suppl.1, A414, Apr. 2017.
45. 杉谷 鮎美, 高橋 立成, 甲斐 幸樹, Mayuko Ichimura, 平 修, 川口 誠, Hirohisa Ogawa, Takaaki Tsunematsu, Koichi Tsuneyama, 野本 一博 and 常山 幸一 :
A case of lipid-rich carcinoma of the breast with numerous hyaline globules(和訳中),
Proceedings of the Japanese Society of Pathology, Vol.106, No.1, 492-493, Mar. 2017.
46. 山下 理子, Shingo Wakatsuki, 遠藤 早希子, 佐竹 宣法, 堀口 英久, 小川 博久 and Koichi Tsuneyama :
「病理夏の学校in徳島」における,検査値解析を用いた全学年参加CPC,
Proceedings of the Japanese Society of Pathology, Vol.106, No.1, 327, Mar. 2017.
47. Takaaki Tsunematsu, Yasusei Kudo, Akiko Yamada, Rieko Arakaki, Hirohisa Ogawa, Koichi Tsuneyama and Naozumi Ishimaru :
胎児性癌細胞におけるユビキチンプロテアソーム経路による未分化性維持機構,
Proceedings of the Japanese Society of Pathology, Vol.106, No.1, 356, Mar. 2017.
48. 堀口 英久, 柿内 聡司, 米田 直樹, 板東 悠太郎, 清久 泰司 and Koichi Tsuneyama :
抗PD-1抗体治療中に致死性肺障害が生じた肺腺癌患者の剖検例,
Proceedings of the Japanese Society of Pathology, Vol.106, No.1, 421, Mar. 2017.
49. Koichi Tsuneyama, 渡邊 俊介, 高橋 徹行, 馬場 逸人, 森本 友樹, Takaaki Tsunematsu and Hirohisa Ogawa :
自然発症メタボリックシンドローム-NASHモデル動物を用いた少量のコーヒー摂取による病態抑制効果の検討,
Proceedings of the Japanese Society of Pathology, Vol.106, No.1, 441, Mar. 2017.
50. Hirohisa Ogawa, Takaaki Tsunematsu, 森本 友樹 and Koichi Tsuneyama :
IL-17/好中球は気道粘膜上皮透過性を増加させFGF-2産生を介した気道平滑筋肥厚を誘導する,
Proceedings of the Japanese Society of Pathology, Vol.106, No.1, 474, Mar. 2017.
51. Hirohisa Ogawa, Takaaki Tsunematsu, 森本 友樹 and Koichi Tsuneyama :
IL-17/好中球は気道粘膜上皮透過性を増加させFGF-2産生を介した気道平滑筋肥厚を誘導する,
Proceedings of the Japanese Society of Pathology, Vol.106, No.1, 474, Mar. 2017.
52. 杉谷 鮎美, 高橋 立成, 甲斐 幸樹, 市村 真祐子, 平 修, 川口 誠, Hirohisa Ogawa, Takaaki Tsunematsu, Koichi Tsuneyama, 野本 一博 and 常山 幸一 :
A case of lipid-rich carcinoma of the breast with numerous hyaline globules(和訳中),
Proceedings of the Japanese Society of Pathology, Vol.106, No.1, 492-493, Mar. 2017.
53. 甲斐 幸樹, 常松 貴明, 杉谷 鮎美, 高橋 立成, Hirohisa Ogawa, 森本 友樹 and Koichi Tsuneyama :
コーヒーに含まれるクロロゲン酸(5-カフェオイルキナ酸:5-CQA)の抗腫瘍効果の検討,
Proceedings of the Japanese Society of Pathology, Vol.106, No.1, 513, Mar. 2017.
54. Toshiaki Yoshimoto, Yu Saitou, Yuji Morine, Koichi Tsuneyama, Satoru Imura, Tetsuya Ikemoto, Shuichi Iwahashi, Masato Yoshikawa, Atsushi Takata and Mitsuo Shimada :
限局性結節性過形成(FNH)術後に再発増殖し肝不全で死亡した一例-切除肝・病理解剖をふまえて-,
第66回日本消化器画像診断研究会, Feb. 2017.
55. 藤村 仁美, Mayumi Takeuchi, Kenji Matsuzaki, Masafumi Harada, Eri Takiguchi, Masato Nishimura, 渡邉 俊介 and Koichi Tsuneyama :
卵巣漿液性癌を背景に発生した大細胞神経内分泌癌の1例,
第127回 日本医学放射線学会 中国・四国地方会, Dec. 2016.
56. Mayumi Takeuchi, Kenji Matsuzaki, Masafumi Harada, Eri Takiguchi, Masato Nishimura, 渡邉 俊介 and Koichi Tsuneyama :
卵巣漿液性癌を背景に発生した大細胞性神経内分泌癌の1例,
第30回日本腹部放射線学会, Jun. 2016.
57. 信 蔵野, Koichi Tsuneyama, 政弘 常名 and 裕 矢冨 :
アポ蛋白Mを用いた播種性血管内凝固症候群,多臓器不全の新規治療法の開発,
Japanese Journal of Thrombosis and Hemostasis, Vol.27, No.2, 250, May 2016.
58. 信 蔵野, Koichi Tsuneyama, 政弘 常名 and 裕 矢冨 :
アポ蛋白Mを用いた播種性血管内凝固症候群,多臓器不全の新規治療法の開発,
Japanese Journal of Thrombosis and Hemostasis, Vol.27, No.2, 250, May 2016.
59. Koichi Tsuneyama :
明日から役立つ肝臓病理 AIH メタボリックシンドローム関連肝疾患に出現するautoimmune featuresの臨床病理学的特徴,
Acta Hepatologica Japonica, Vol.57, No.Suppl.1, A143, Apr. 2016.
60. Koichi Tsuneyama, Hirohisa Ogawa, Takaaki Tsunematsu and Hisanori Uehara :
新生児期ストレプトゾトシン投与4CS系マウスは通常食飼育によって持続高血糖なしに肝腫瘍を発症する,
Proceedings of the Japanese Society of Pathology, Vol.105, No.1, 384, Apr. 2016.
61. Hirohisa Ogawa, Takaaki Tsunematsu, Hisanori Uehara and Koichi Tsuneyama :
ダニ抗原経鼻感作はIL-17/好中球を増加させ平滑筋肥厚を伴う気道リモデリングを誘導する,
Proceedings of the Japanese Society of Pathology, Vol.105, No.1, 386, Apr. 2016.
62. Hisanori Uehara, Hirohisa Ogawa, Takaaki Tsunematsu and Koichi Tsuneyama :
前立腺癌細胞の骨内増殖におけるlipolysis stimulated lipoprotein receptorの役割,
Proceedings of the Japanese Society of Pathology, Vol.105, No.1, 466, Apr. 2016.
63. 秀樹 八田, 隆彦 中嶋, Koichi Tsuneyama, 伸一 林, 重治 三輪, 尚 南坂, 健志 西田, ゆう子 中西 and 穣二 井村 :
免疫染色におけるホウ酸含有緩衝液の有効性 室温放置により抗原性が減弱した標本の賦活法,
Proceedings of the Japanese Society of Pathology, Vol.105, No.1, 529, Apr. 2016.
64. 健志 西田, Koichi Tsuneyama, 伸一 林, 重治 三輪, 隆彦 中嶋, 尚 南坂, 秀樹 八田 and 穣二 井村 :
肥満・糖尿病マウスを用いた,メタボリックシンドロームに対する地域伝承発酵食品の有効性の検証,
Proceedings of the Japanese Society of Pathology, Vol.105, No.1, 543, Apr. 2016.
65. Takaaki Tsunematsu, Yasusei Kudo, Akiko Yamada, Rieko Arakaki, Hirohisa Ogawa, Hisanori Uehara, Naozumi Ishimaru and Koichi Tsuneyama :
染色体パッセンジャー複合体タンパク質Borealinのユビキチン分解の意義とその癌化への関与,
Proceedings of the Japanese Society of Pathology, Vol.105, No.1, 548, Apr. 2016.
66. 良祐 別所, Takaaki Tsunematsu, Hirohisa Ogawa, Hisanori Uehara and Koichi Tsuneyama :
自然発症2型糖尿病モデルマウスにおける膵島の外分泌腺組織への変化がβ細胞の機能不全に果たす役割,
Proceedings of the Japanese Society of Pathology, Vol.105, No.1, 595, Apr. 2016.
67. 徹行 高橋, Hisanori Uehara, Koichi Tsuneyama and 貴雄 土方 :
プロスタグランジンE2受容体シグナリング阻害は膵臓がんにおけるIGF-1受容体シグナリングを介した増殖刺激を消失させる,
日本薬学会年会要旨集, No.4, 202, Mar. 2016.
68. 裕恵 本田, 良憲 長井, 孝之 松永, 直樹 岡本, 康春 渡邉, Koichi Tsuneyama, 宏明 林, 勲 藤井, 嘉勝 平井 and 聖志 高津 :
甘草成分イソリクイリチゲニンはNLRP3インフラマソーム活性化を阻害し,2型糖尿病の慢性炎症を改善する,
日本薬学会年会要旨集, No.3, 140, Mar. 2016.
69. Masaki TAKEUCHI, Shingo ODA, Koichi Tsuneyama and Tsuyoshi YOKOI :
Identification of serum miRNAs as diagnostic biomarkers for sinusoidal obstruction syndrome in rats,
Annual Meeting of the Japanese Society of Toxicology, Vol.43, No.0, P-80, 2016.
(DOI: 10.14869/toxpt.43.1.0_P-80,   CiNii: 130005260889)
70. 猪子 未希, Hirokazu Ogino, Mayuri Nakano, 岡崎 弘泰, 大塚 憲司, Hisatsugu Goto, Jun Kishi, Masaki Hanibuchi, Yoshimi Bando, Koichi Tsuneyama and Yasuhiko Nishioka :
脳,口蓋垂,喉頭および小腸への遠隔転移を形成する稀な臨床経過をたどった右上葉原発多形癌の一剖検例,
第54回日本呼吸器学会中国・四国地方会, Dec. 2015.
71. Mayuko Ichimura, 畑中 麻衣子, Koichi Tsuneyama, 加藤 滋子 and 大曲 勝久 :
An animal model of NASH with advanced fibrosis induced by high-fat and high-cholesterol diet,
第67回日本栄養食糧学会大会, May 2013.
72. 藤坂 志帆, 薄井 勲, Takeshi Oya, 金谷 由紀子, 山崎 夕, Agussalim Bukhari, 鈴木 ひかり, 仙田 聡子, 高崎 一朗, Koichi Tsuneyama, 浦風 雅春, 小林 正 and 戸辺 一之 :
テルミサルタンは脂肪組織のM1マクロファージを選択的に減少させることでインスリン抵抗性を改善する,
Journal of the The Japan Diabetes Society, Vol.51, No.Suppl.1, S-348, Apr. 2008.
73. 石澤 伸, 高橋 博之, Takeshi Oya and Koichi Tsuneyama :
Diffuse-type giant cell tumorの1例,
第54回 日本病理学会中部支部交見会, Dec. 2004.

Patent:

1. Mayuko Ichimura, Koichi Tsuneyama and 大曲 勝久 : 肝の線維化を伴い得るNAFLDモデル動物,その作製方法,及びそれを作製するための飼料, (Oct. 2017), .
2. 生谷 尚士, 高津 聖志, Koichi Tsuneyama, 川口 誠 and 福岡 順也 : ヒト肺高血圧症に類似した病態を示すモデル動物及びその作成方法, 2013-183870 (Sep. 2013), 2015-50941 (Mar. 2015), .

Grants-in-Aid for Scientific Research (KAKEN Grants Database @ NII.ac.jp)

  • 肝星細胞制御による肝移植後グラフト内肝癌再発抑制機構の解明 (Project/Area Number: 18K08573 )
  • 非アルコール性脂肪性肝炎の発症・進展における、胆汁酸、短鎖脂肪酸の役割の解明 (Project/Area Number: 18K07069 )
  • 非アルコール性脂肪肝炎における肝再生機能不全の解明と統合的治療法の開発 (Project/Area Number: 18H02871 )
  • 非アルコール性肝障害の発症機序解明および早期診断法の確立と予防法の提案 (Project/Area Number: 17H00881 )
  • Establishment of new analytical method for visualizing chemical agents and xenobiotics on pathology speciments (Project/Area Number: 15K15098 )
  • Pathological analysis of cadmium and its microenvironment in patients with itai-itai disease (Project/Area Number: 25670175 )
  • Effect of obesity and diabetes on liver cancer and tumor-associated macrophage polarization (Project/Area Number: 25461333 )
  • Development of methods for reducing volume and reutilization of waste seaweeds with a novel species bacterium Myt-1 capable of degrading seaweeds. (Project/Area Number: 25340121 )
  • Kampo medicine pharmacology-based clarification and identification of etiologic factors and their function responsible for ADHD (Project/Area Number: 24659347 )
  • New analytical technology in the field of pathology clarified effectiveness of Kampo formula (Project/Area Number: 24390181 )
  • Detection of novel actions of kampo medicines for lipid metabolism by lipidomic analysis (Project/Area Number: 23590873 )
  • Sharing pathogenic mechanism between non-alcoholic steatohepatitis and primary biliary cirrhosis (Project/Area Number: 21590433 )
  • Studies on endogenous neuronal mediator with responsibility for anti-dementia effect of Kampo medicine (Project/Area Number: 20390197 )
  • Molecular pathological analysis of pathogenesis of non-alcoholic steatohepatitis: Propose of new treatment approach (Project/Area Number: 18590324 )
  • Role of p 53 codon 72 polymorphism in EBV-related gastric cancer (Project/Area Number: 17590297 )
  • 非アルコール性脂肪性肝炎発症・進展に関する脂質過酸化、及び糖化反応の役割 (Project/Area Number: 16790223 )
  • Study on the role of mutated α-tubulin in the progression of malignant tumors (Project/Area Number: 15590296 )
  • 胆道系におけるアレルギー機序の解明 (Project/Area Number: 14770072 )
  • ヒト肝臓の幹細胞の研究:c-kit 受容体-stem cell factor系の発現を中心に (Project/Area Number: 12770085 )
  • Pathological and biological analysis of congenital hepatic fibrosis and Caroli's disease -A comparative study using an animal model for the disease (Project/Area Number: 12470044 )
  • 慢性胆管炎・特に肝内結石症での胆管硬化と肥満細胞との関連性・胆管上皮でのStem Cell Factorの発現を中心にして (Project/Area Number: 10770074 )
  • Search by Researcher Number (10293341)