Tokushima University > Graduate School of Biomedical Sciences > 医学域 > Medical Science > Physiological Sciences > Department of Cell Biology >
Tokushima University > Faculty of Medicine > School of Medicine > Course of Preventive Medicine > Cell Biology >
Tokushima University > Graduate School of Medical Sciences > Medical Science > Course of Preventive Medicine >
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Research Activity

His Web Page

Field of Study

Cell Biology

Subject of Study

Cell polarity and migration

Book / Paper


1. Shusaku Kurisu :
改訂 タンパク質実験ハンドブック,第9章・第11章,
YODOSHA CO., LTD., Jan. 2011.
2. Shusaku Kurisu :
細胞遊走研究のパラダイムシフト~二次元から三次元へ (第4章2),
YODOSHA CO., LTD., Aug. 2006.

Academic Paper (Judged Full Paper):

1. Jenna R. Sternberg, Andrew E. Prendergast, Lucie Brosse, Yasmine Cantaut-Belarif, Olivier Thouvenin, Adeline Orts-DelImmagine, Laura Castillo, Lydia Djenoune, Shusaku Kurisu, Jonathan R. McDearmid, Pierre-Luc Bardet, Claude Boccara, Hitoshi Okamoto, Patrick Delmas and Claire Wyart :
Pkd2l1 is required for mechanoception in cerebrospinal fluid-contacting neurons and maintenance of spine curvature,
Nature Communications, Vol.9, No.1, 3804, 2018.
(Tokushima University Institutional Repository: 114080,   DOI: 10.1038/s41467-018-06225-x,   PubMed: 30228263)
2. Miki Fukumoto, Shusaku Kurisu, Tesshi Yamada and Tadaomi Takenawa :
α-Actinin-4 enhances colorectal cancer cell invasion by suppressing focal adhesion maturation.,
PLoS ONE, Vol.10, No.4, e0120616, 2015.
(DOI: 10.1371/journal.pone.0120616,   PubMed: 25860875)
3. Shiro Suetsugu, Shusaku Kurisu and Tadaomi Takenawa :
Dynamic shaping of cellular membranes by phospholipids and membrane-deforming proteins.,
Physiological Reviews, Vol.94, No.4, 1219-1248, 2014.
(DOI: 10.1152/physrev.00040.2013,   PubMed: 25287863)
4. Kazuya Tsujita, Akihiro Kondo, Shusaku Kurisu, Junya Hasegawa, Toshiki Itoh and Tadaomi Takenawa :
Antagonistic regulation of F-BAR protein assemblies controls actin polymerization during podosome formation.,
Journal of Cell Science, Vol.126, No.10, 2267-2278, 2013.
5. Shusaku Kurisu and Tadaomi Takenawa :
WASP and WAVE family proteins: friends or foes in cancer invasion?,
Cancer Science, Vol.101, No.10, 2093-2104, 2010.
6. Shusaku Kurisu and Tadaomi Takenawa :
The WASP and WAVE family proteins.,
Genome Biology, Vol.10, No.6, 2009.
7. Daisuke Yamazaki, Shusaku Kurisu and Tadaomi Takenawa :
Involvement of Rac and Rho signaling in cancer cell motility in 3D substrates.,
Oncogene, Vol.28, No.13, 1570-1583, 2009.
(DOI: 10.1038/onc.2009.2,   PubMed: 19234490,   Elsevier: Scopus)
8. Shiro Suetsugu, Shusaku Kurisu, Tsukasa Oikawa, Daisuke Yamazaki, Atsushi Oda and Tadaomi Takenawa :
Optimization of WAVE2 complex-induced actin polymerization by membrane-bound IRSp53, PIP3, and Rac.,
The Journal of Cell Biology, Vol.173, No.4, 571-585, 2006.
9. Daisuke Yamazaki, Shusaku Kurisu and Tadaomi Takenawa :
Regulation of cancer cell motility through actin reorganization.,
Cancer Science, Vol.96, No.7, 379-386, 2005.
10. Shusaku Kurisu, Shiro Suetsugu, Daisuke Yamazaki, Hideki Yamaguchi and Tadaomi Takenawa :
Rac-WAVE2 signaling is involved in the invasive and metastatic phenotypes of murine melanoma cells.,
Oncogene, Vol.24, No.8, 1309-1319, 2005.
11. Kazuhiro Kawamura, Kazunori Takano, Shiro Suetsugu, Shusaku Kurisu, Daisuke Yamazaki, Hiroaki Miki, Tadaomi Takenawa and Takeshi Endo :
N-WASP and WAVE2 acting downstream of phosphatidylinositol 3-kinase are required for myogenic cell migration induced by hepatocyte growth factor.,
The Journal of Biological Chemistry, Vol.279, No.52, 54862-54871, 2004.
12. Shiro Suetsugu, Daisuke Yamazaki, Shusaku Kurisu and Tadaomi Takenawa :
Differential roles of WAVE1 and WAVE2 in dorsal and peripheral ruffle formation for fibroblast cell migration.,
Developmental Cell, Vol.5, No.4, 595-609, 2003.

Review, Commentary:

1. Shusaku Kurisu and Tadaomi Takenawa :
3-7 細胞運動と細胞がん化,
がん研究のいま2:がん細胞の生物学, 94-110, Feb. 2006.

Proceeding of International Conference:

1. Shusaku Kurisu, Toshiki Itoh and Tadaomi Takenawa :
Microvillar tip-localized interaction between IRSp53 and PI(4,5)P2 drives brush border assembly in kidney epithelial cells.,
ASCB/IFCB annual meeting, Philadelphia, Dec. 2014.

Proceeding of Domestic Conference:

1. Shusaku Kurisu and Shigenobu Yonemura :
The epithelial apico-basal boundary is defined by a cortical actomyosin ring,
Joint Annual Meeting of 71st JSCB & 19 th PAAJ, Jun. 2019.
2. Shusaku Kurisu and Shigenobu Yonemura :
第4回日本メカノバイオロジー学会学術総会, Mar. 2019.
3. Shusaku Kurisu and Shigenobu Yonemura :
Determination of protein composition at epithelial cell-cell junctions by CRISPR/Cas9-mediated fluorescent protein knockin,
Joint Annual Meeting of 70th JSCB and 51st JSDB co-sponsored by APDBN, Jun. 2018.
4. Shusaku Kurisu and Tadaomi Takenawa :
IRSp53 family of I-BAR domain proteins regulates microvillius morphogenesis by sculpting the apical plasma membrane.,
第65回日本細胞生物学会大会, Jun. 2013.

Et cetera, Workshop:

1. Shusaku Kurisu :
Cortical actinによる単一上皮細胞の極性化の制御,
上皮・ジャンクション研究会, Nov. 2018.
2. Shusaku Kurisu :
Epithelial Junction Conference, Dec. 2017.
3. Shusaku Kurisu :
Epithelium Junction Conference, Jan. 2017.
4. Shusaku Kurisu :
Epithelium Junction Conference, Jul. 2016.

Grants-in-Aid for Scientific Research (KAKEN Grants Database @

  • 蛍光タンパク質ノックインによる上皮メカノセンサーの分子数計測 (Project/Area Number: 18K06932 )
  • Molecular insight into the motile phenotype of the leader cells in epithelial collective migration (Project/Area Number: 25860215 )
  • Search by Researcher Number (40525531)