Tokushima UniversityGraduate School of Biomedical Sciences医学域Medical SciencePhysiological SciencesDepartment of Cell Biology
Tokushima UniversityFaculty of MedicineSchool of MedicineCourse of Preventive MedicineCell Biology
Tokushima UniversityGraduate School of MedicineMedicineCourse of Preventive Medicine
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Field of Study

Cell Biology

Subject of Study

Cell polarity and migration

Book / Paper


1. Shusaku Kurisu :
改訂 タンパク質実験ハンドブック,第9章・第11章,
YODOSHA CO., LTD., Jan. 2011.
2. Shusaku Kurisu :
細胞遊走研究のパラダイムシフト~二次元から三次元へ (第4章2),
YODOSHA CO., LTD., Aug. 2006.

Academic Paper (Judged Full Paper):

1. Aya Tentaku, Shusaku Kurisu, Kurumi Sejima, Toshiki Nagao, Akira Takahashi and Shigenobu Yonemura :
Proximal deposition of collagen IV by fibroblasts contributes to basement membrane formation by colon epithelial cells invitro.,
The FEBS Journal, Vol.289, No.23, 7466-7485, 2022.
(Tokushima University Institutional Repository: 117543,   DOI: 10.1111/febs.16559,   PubMed: 35730982)
2. Ayuko Sakane, Taka-aki Yano, Takayuki Uchihashi, Kazuki Horikawa, Yusuke Hara, Issei Imoto, Shusaku Kurisu, Hiroshi Yamada, Kohji Takei and Takuya Sasaki :
JRAB/MICAL-L2 undergoes liquid-liquid phase separation to form tubular recycling endosomes.,
Communications Biology, Vol.4, No.1, 551, 2021.
(Tokushima University Institutional Repository: 117215,   DOI: 10.1038/s42003-021-02080-7,   PubMed: 33976349)
3. Jenna R. Sternberg, Andrew E. Prendergast, Lucie Brosse, Yasmine Cantaut-Belarif, Olivier Thouvenin, Adeline Orts-DelImmagine, Laura Castillo, Lydia Djenoune, Shusaku Kurisu, Jonathan R. McDearmid, Pierre-Luc Bardet, Claude Boccara, Hitoshi Okamoto, Patrick Delmas and Claire Wyart :
Pkd2l1 is required for mechanoception in cerebrospinal fluid-contacting neurons and maintenance of spine curvature,
Nature Communications, Vol.9, No.1, 3804, 2018.
(Tokushima University Institutional Repository: 114080,   DOI: 10.1038/s41467-018-06225-x,   PubMed: 30228263)
4. Miki Fukumoto, Shusaku Kurisu, Tesshi Yamada and Tadaomi Takenawa :
α-Actinin-4 enhances colorectal cancer cell invasion by suppressing focal adhesion maturation.,
PLoS ONE, Vol.10, No.4, e0120616, 2015.
(DOI: 10.1371/journal.pone.0120616,   PubMed: 25860875)
5. Shiro Suetsugu, Shusaku Kurisu and Tadaomi Takenawa :
Dynamic shaping of cellular membranes by phospholipids and membrane-deforming proteins.,
Physiological Reviews, Vol.94, No.4, 1219-1248, 2014.
(DOI: 10.1152/physrev.00040.2013,   PubMed: 25287863)
6. Kazuya Tsujita, Akihiro Kondo, Shusaku Kurisu, Junya Hasegawa, Toshiki Itoh and Tadaomi Takenawa :
Antagonistic regulation of F-BAR protein assemblies controls actin polymerization during podosome formation.,
Journal of Cell Science, Vol.126, No.10, 2267-2278, 2013.
(DOI: 10.1242/jcs.122515,   PubMed: 23525018,   Elsevier: Scopus)
7. Shusaku Kurisu and Tadaomi Takenawa :
WASP and WAVE family proteins: friends or foes in cancer invasion?,
Cancer Science, Vol.101, No.10, 2093-2104, 2010.
(DOI: 10.1111/j.1349-7006.2010.01654.x,   PubMed: 20707804,   CiNii: 1573105976081715712)
8. Shusaku Kurisu and Tadaomi Takenawa :
The WASP and WAVE family proteins.,
Genome Biology, Vol.10, No.6, 226, 2009.
(DOI: 10.1186/gb-2009-10-6-226,   PubMed: 19589182)
9. Daisuke Yamazaki, Shusaku Kurisu and Tadaomi Takenawa :
Involvement of Rac and Rho signaling in cancer cell motility in 3D substrates.,
Oncogene, Vol.28, No.13, 1570-1583, 2009.
(DOI: 10.1038/onc.2009.2,   PubMed: 19234490,   Elsevier: Scopus)
10. Shiro Suetsugu, Shusaku Kurisu, Tsukasa Oikawa, Daisuke Yamazaki, Atsushi Oda and Tadaomi Takenawa :
Optimization of WAVE2 complex-induced actin polymerization by membrane-bound IRSp53, PIP3, and Rac.,
The Journal of Cell Biology, Vol.173, No.4, 571-585, 2006.
(DOI: 10.1083/jcb.200509067,   PubMed: 16702231)
11. Daisuke Yamazaki, Shusaku Kurisu and Tadaomi Takenawa :
Regulation of cancer cell motility through actin reorganization.,
Cancer Science, Vol.96, No.7, 379-386, 2005.
(DOI: 10.1111/j.1349-7006.2005.00062.x,   PubMed: 16053508)
12. Shusaku Kurisu, Shiro Suetsugu, Daisuke Yamazaki, Hideki Yamaguchi and Tadaomi Takenawa :
Rac-WAVE2 signaling is involved in the invasive and metastatic phenotypes of murine melanoma cells.,
Oncogene, Vol.24, No.8, 1309-1319, 2005.
(DOI: 10.1038/sj.onc.1208177,   PubMed: 15608687)
13. Kazuhiro Kawamura, Kazunori Takano, Shiro Suetsugu, Shusaku Kurisu, Daisuke Yamazaki, Hiroaki Miki, Tadaomi Takenawa and Takeshi Endo :
N-WASP and WAVE2 acting downstream of phosphatidylinositol 3-kinase are required for myogenic cell migration induced by hepatocyte growth factor.,
The Journal of Biological Chemistry, Vol.279, No.52, 54862-54871, 2004.
(DOI: 10.1074/jbc.M408057200,   PubMed: 15496413)
14. Shiro Suetsugu, Daisuke Yamazaki, Shusaku Kurisu and Tadaomi Takenawa :
Differential roles of WAVE1 and WAVE2 in dorsal and peripheral ruffle formation for fibroblast cell migration.,
Developmental Cell, Vol.5, No.4, 595-609, 2003.
(DOI: 10.1016/s1534-5807(03)00297-1,   PubMed: 14536061)

Review, Commentary:

1. Shusaku Kurisu and Shigenobu Yonemura :
Fluorescent tagging of endogenous proteins and its application to protein quantification in subcellular compartments,
The Cell, Vol.55, No.5, 320-322, Apr. 2023.
2. Shusaku Kurisu and Shigenobu Yonemura :
Basement membrane dynamics in epithelial morphogenesis,
Shikoku Acta Medica, Vol.77, No.1, 2, 17-24, Apr. 2021.
(Tokushima University Institutional Repository: 116033,   CiNii: 1050006895493034368)
3. Shusaku Kurisu and Tadaomi Takenawa :
3-7 細胞運動と細胞がん化,
がん研究のいま2:がん細胞の生物学, 94-110, Feb. 2006.

Proceeding of International Conference:

1. Shusaku Kurisu, Toshiki Itoh and Tadaomi Takenawa :
Microvillar tip-localized interaction between IRSp53 and PI(4,5)P2 drives brush border assembly in kidney epithelial cells.,
ASCB/IFCB annual meeting, Philadelphia, Dec. 2014.

Proceeding of Domestic Conference:

1. Shusaku Kurisu and Shigenobu Yonemura :
Regulation of epithelial apicobasal cell polarity by phospholipase C-beta,
第75回日本細胞生物学会大会, Jun. 2023.
2. Shusaku Kurisu, Aya Tentaku and Shigenobu Yonemura :
大腸上皮細胞のin vitro基底膜形成における近接線維芽細胞由来IV型コラーゲンの寄与,
ムーンショット目標2 第1回若手ワークショップ, Nov. 2022.
3. Shusaku Kurisu, Tentaku Aya and Shigenobu Yonemura :
大腸上皮細胞のin vitro基底膜形成における近接線維芽細胞由来IV型コラーゲンの寄与,
第74回日本細胞生物学会大会, Jun. 2022.
4. Aya Tentaku, Shusaku Kurisu, Akira Takahashi and Shigenobu Yonemura :
上皮基底膜 IV型コラーゲンの動態解析,
第94回日本生化学会大会, Nov. 2021.
5. Shusaku Kurisu and Shigenobu Yonemura :
Quantitative changes of actin-binding proteins in mechanical responses of epithelial cell-cell adhesion,
The 73rd Annual Meeting of the Japan Society for Cell Biology, Jul. 2021.
6. Shusaku Kurisu and Shigenobu Yonemura :
The roles of cortical actin rings in the establishment of epithelial cell polarity,
The 126th Annual Meeting of The Japanese Association of Anatomists, The 98th Annual Meeting of The Physiological Society of Japan, Mar. 2021.
7. Aya Tentaku, Shusaku Kurisu, Akira Takahashi and Shigenobu Yonemura :
第262回徳島医学会学術集会, Mar. 2021.
8. Shusaku Kurisu :
第262回徳島医学会学術集会, Mar. 2021.
9. Shusaku Kurisu and Shigenobu Yonemura :
Protein quantification at epithelial cell-cell junctions reveals a differential distribution of the actin-associated components,
The 72nd Annual Meeting of the Japan Society for Cell Biology, Jun. 2020.
10. Shusaku Kurisu and Shigenobu Yonemura :
The epithelial apico-basal boundary is defined by a cortical actomyosin ring,
Joint Annual Meeting of 71st JSCB & 19 th PAAJ, Jun. 2019.
11. Shusaku Kurisu and Shigenobu Yonemura :
第4回日本メカノバイオロジー学会学術総会, Mar. 2019.
12. Shusaku Kurisu and Shigenobu Yonemura :
Determination of protein composition at epithelial cell-cell junctions by CRISPR/Cas9-mediated fluorescent protein knockin,
Joint Annual Meeting of 70th JSCB and 51st JSDB co-sponsored by APDBN, Jun. 2018.
13. Shusaku Kurisu, Toshiki Itoh and Tadaomi Takenawa :
第56回日本脂質生化学会大会, Jun. 2014.
14. Shusaku Kurisu and Tadaomi Takenawa :
IRSp53 family of I-BAR domain proteins regulates microvillius morphogenesis by sculpting the apical plasma membrane.,
第65回日本細胞生物学会大会, Jun. 2013.

Et cetera, Workshop:

1. Shusaku Kurisu :
Epithelial Junction Conference, Nov. 2020.
2. Shusaku Kurisu :
Cortical actinによる単一上皮細胞の極性化の制御,
上皮・ジャンクション研究会, Nov. 2018.
3. Shusaku Kurisu :
Epithelial Junction Conference, Dec. 2017.
4. Shusaku Kurisu :
Epithelium Junction Conference, Jan. 2017.
5. Shusaku Kurisu :
Epithelium Junction Conference, Jul. 2016.

Grants-in-Aid for Scientific Research (KAKEN Grants Database @

  • Determination of protein composition of the epithelial mechanosensing complex by CRISPR/Cas9-mediated fluorescent protein knock-in (Project/Area Number: 18K06932 )
  • Molecular insight into the motile phenotype of the leader cells in epithelial collective migration (Project/Area Number: 25860215 )
  • Search by Researcher Number (40525531)