徳島大学 / 教育研究者総覧 --- 笠井飛鳥

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徳島大学 ⟩ 病院 ⟩ 中央診療施設等 ⟩ 手術部 ⟩
徳島大学 ⟩ 医学部 ⟩ 医学科 ⟩ 病態情報医学講座 ⟩ 麻酔・疼痛治療医学分野 ⟩
徳島大学 ⟩ 病院 ⟩ 診療科 ⟩ 脳·神経·精神科 ⟩ 麻酔科 ⟩

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研究活動

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研究テーマ

著書・論文

学術論文(審査論文):

1.	Michiko Kinoshita, Sarara Mutoh, Asuka Kasai, Ryosuke Kawanishi and Katsuya Tanaka : General Anesthesia in a Patient With Neuronal Intranuclear Inclusion Disease: A Case Report., A&A Practice, Vol.16, No.10, 2022. (要約) Neuronal intranuclear inclusion disease (NIID) is a progressive neurodegenerative disease with diverse clinical manifestations, including dementia and muscle weakness. We summarize anesthetic considerations in reporting general anesthesia for a 58-year-old man with bladder dysfunction and cerebellar ataxia who was diagnosed with NIID. The patient developed postinduction hypotension relevant to autonomic neuropathy. The potential risks, such as prolonged reaction to neuromuscular blocking agent, postoperative delirium, and worsening of NIID-related symptoms, were also considered. The responsiveness to anesthetics may vary widely from case t case. As the number of NIID cases increases, a better understanding of NIID is needed. (出版サイトへのリンク) ● Publication site (DOI): 10.1213/XAA.0000000000001633 (文献検索サイトへのリンク) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 36599032 ● Search Scopus @ Elsevier (PMID): 36599032 ● Search Scopus @ Elsevier (DOI): 10.1213/XAA.0000000000001633 (DOI: 10.1213/XAA.0000000000001633, PubMed: 36599032)
2.	箕田直治, 川人伸次, 里見志帆, 笠井飛鳥, 曽我朋宏, 酒井陽子, 高石和美, 北畑洋, 堤保夫, 田中克哉 : 慢性炎症性脱髄性多発根ニューロパチー患者に対する肝切除術の麻酔経験, 麻酔, Vol.68, No.4, 409-412, 2019年. (キーワード) 慢性炎症性脱髄性多発根ニューロパチー(CIDP) / 全身麻酔 / 超音波ガイド下神経ブロック / 肝切除術 / chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) / general anesthesia / ultrasound-guided peripheral nerve block / hepatectomy (文献検索サイトへのリンク) ● CiNii @ 国立情報学研究所 (CRID): 1520009407524776192 (CiNii: 1520009407524776192)
3.	Nami Kakuta, Yasuo Tsutsumi, Chiaki Murakami, Yoko Sakai, Takuro Oyama, Asuka Kasai, Katsuyoshi Kume and Katsuya Tanaka : Effectiveness of using non-invasive continuous arterial pressure monitoring with ClearSight in hemodynamic monitoring during living renal transplantation in a recipient:a case report., The Journal of Medical Investigation : JMI, Vol.65, No.1.2, 139-141, 2018. (要約) We investigated the effectiveness of the ClearSight system for hemodynamic management during kidney transplantation for a recipient. The recipient was to receive a kidney transplant from his mother under general anesthesia. We used continuous noninvasive finger-cuff-based monitoring of blood pressure, provided by the ClearSight system, and stroke volume variation to predict fluid responsiveness. We used of a balanced anesthetic technique and stringent monitoring standards to ensure a successful outcome for the patient. This case demonstrated that ClearSight has the potential to improve patient monitoring in hemodynamically stable patients who received kidney transplantation under general anesthesia. J. Med. Invest. 65:139-141, February, 2018. (キーワード) Adult / Arterial Pressure / Hemodynamic Monitoring / Humans / Kidney Transplantation / Male (徳島大学機関リポジトリ) ● Metadata: 111450 (出版サイトへのリンク) ● Publication site (DOI): 10.2152/jmi.65.139 (文献検索サイトへのリンク) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 29593185 ● Search Scopus @ Elsevier (PMID): 29593185 ● Search Scopus @ Elsevier (DOI): 10.2152/jmi.65.139 (徳島大学機関リポジトリ: 111450, DOI: 10.2152/jmi.65.139, PubMed: 29593185)
4.	Chiaki Murakami, Nami Kakuta, Katsuyoshi Kume, Yoko Sakai, Asuka Kasai, Takuro Oyama, Katsuya Tanaka and Yasuo Tsutsumi : A comparison of fosaprepitant and ondansetron for preventing postoperative nausea and vomiting in moderate to high risk patients: A retrospective database analysis., BioMed Research International, Vol.2017, 5703528, 2017. (要約) Postoperative nausea and vomiting (PONV) occur in 30-50% of patients undergoing general anesthesia and in 70-80% of high PONV risk patients. In this study, we investigated the efficacy of fosaprepitant, a neurokinin-1 (NK1) receptor antagonist, compared to ondansetron, a selective 5-hydroxytryptamine type 3 (5-HT3) receptor antagonist, in moderate to high PONV risk patients from our previous randomized controlled trials. Patients (171 patients from 4 pooled studies) with the Apfel simplified score ≥ 2 and undergoing general anesthesia were randomly allocated to receive intravenous fosaprepitant 150 mg (NK1 group, = 82) and intravenous ondansetron 4 mg (ONS group, = 89) before induction of anesthesia. Incidence of vomiting was significantly lower in the NK1 group compared to the ONS group 0-2, 0-24, and 0-48 hours after surgery (2 versus 17%, 2 versus 28%, and 2 versus 29%, resp.). However, no significant differences in PONV, complete response, rescue antiemetic use, and nausea score were observed between groups 0-48 hours after surgery. In moderate to high PONV risk patients, fosaprepitant decreased the incidence of vomiting and was superior to ondansetron in preventing postoperative vomiting 0-48 hours after surgery. (キーワード) Adult / Aged / Aged, 80 and over / Databases as Topic / Demography / Humans / Middle Aged / Morpholines / Ondansetron / Postoperative Care / Postoperative Nausea and Vomiting / Retrospective Studies / Risk Factors / Young Adult (徳島大学機関リポジトリ) ● Metadata: 112392 (出版サイトへのリンク) ● Publication site (DOI): 10.1155/2017/5703528 (文献検索サイトへのリンク) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 29410964 ● Search Scopus @ Elsevier (PMID): 29410964 ● Search Scopus @ Elsevier (DOI): 10.1155/2017/5703528 (徳島大学機関リポジトリ: 112392, DOI: 10.1155/2017/5703528, PubMed: 29410964)
5.	Shiho Satomi, Asuka Kasai, Eisuke Hamaguchi, Yasuo Tsutsumi and Katsuya Tanaka : Normothermic Cardiopulmonary Bypass in Patient with Waldenstroms Macroglobulinemia and Cryoglobulinemia: A Case Report., A & A Case Reports, Vol.9, No.6, 162-163, 2017. (要約) Waldenström's macroglobulinemia (WM) manifests as hyperviscosity syndrome. Cryoglobulinemia, which may increase blood viscosity or induce thrombosis in association with decreased body temperature, can occur in combination with WM. We describe the management of an 82-year-old woman with WM, hyperviscosity syndrome, and cryoglobulinemia who required open aortic valve replacement. Decreased body temperature in this patient was prevented during cardiopulmonary bypass by using a forced air warming system and normothermic cardioplegia with continuous warm blood cardioplegia perfusion. (キーワード) Aged, 80 and over / Aortic Valve / Cardiopulmonary Bypass / Cryoglobulinemia / Female / Heart Valve Prosthesis / Humans / Treatment Outcome / Waldenstrom Macroglobulinemia (出版サイトへのリンク) ● Publication site (DOI): 10.1213/XAA.0000000000000555 (文献検索サイトへのリンク) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 28520564 ● Summary page in Scopus @ Elsevier: 2-s2.0-85042463059 (DOI: 10.1213/XAA.0000000000000555, PubMed: 28520564, Elsevier: Scopus)

総説・解説:

1.	田中克哉, 笠井飛鳥, 大山拓朗 : PART2 術前合併症アップデート胃切除・食道切除術後患者, LiSA, Vol.27, No.2, 157-162, 2020年9月. (出版サイトへのリンク) ● Publication site (DOI): 10.11477/mf.3104200166 (文献検索サイトへのリンク) ● CiNii @ 国立情報学研究所 (CRID): 1390853649577523072 ● Search Scopus @ Elsevier (DOI): 10.11477/mf.3104200166 (DOI: 10.11477/mf.3104200166, CiNii: 1390853649577523072)

国際会議:

1.	Asuka Kasai, Kouhei Fukuta, Katsuya Tanaka, Nami Kakuta and Yasuo Tsutsumi : The effect of intraoperative glucose load on metabolism in patients with diabetes mellitus., American Society of Anesthesiologists 2017 Annual Meeting, Oct. 2017.
2.	Kouhei Fukuta, Asuka Kasai, Katsuya Tanaka, Yoko Sakai and Yasuo Tsutsumi : The Influence of Glucose Load on Metabolism in Elderly Patients During Surgery Using Remifentanil-induced Anesthesia, American Society of Anesthesiologists 2017 Annual Meeting, Oct. 2017.
3.	Takuro Oyama, Nami Kakuta, Asuka Kasai, Naoji Mita, Katsuyoshi Kume and Katsuya Tanaka : Effect of Jelly type carbohydrate on metabolism and evaluation of its excretion in healthy subjects., American Society of Anesthesiologists 2017 Annual Meeting, Oct. 2017.

国内講演発表:

1.	曽我朋宏, 笠井飛鳥, 箕田直治, 川人伸次, 田中克哉 : 高度側弯，広範囲脊椎固定術後のSMA患者に対するヌシネルセン投与を複数回行った症例, 日本ペインクリニック学会第56回学術集会, 2022年7月.
2.	笠井飛鳥, 曽我朋宏, 田中克哉 : トラマドール製剤の長期投与中に性腺機能不全を認めた1症例, 日本ペインクリニック学会第56回学術集会, 2022年7月.
3.	曽我朋宏, 川人伸次, 笠井飛鳥, 箕田直治, 高石和美, 木下浩之, 田中克哉 : 冠攣縮性狭心症を合併した妊婦に対する硬膜外無痛分娩の1症例, 第42回日本循環制御医学会総会・学術集会, 2021年7月.
4.	富山芳信, 川西良典, 笠井飛鳥 : 腹腔鏡胸腔鏡手術時間の年次推移, 日本手術医学会誌, Vol.41, No.Supplement, 164, 2019年9月.
5.	富山芳信, 川西良典, 笠井飛鳥, 石川雄樹, 板東悠太郎 : 手術終了ー退室時間に影響及ぼす諸因子の検討, 麻酔, Vol.67, 2019年5月.
6.	里見志帆, 笠井飛鳥, 木下浩之, 川人伸次, 田中克哉 : 常温血性心筋保護持続冠潅流による開心術の麻酔経験, 第38回日本循環制御医学会, 2017年6月.
7.	笠井飛鳥, 福田浩平, 角田奈美, 堤保夫, 田中克哉 : 糖尿病患者におけるレミフェンタニル麻酔と糖負荷が代謝に与える影響, 日本麻酔科学会第64回学術集会, 2017年6月.
8.	福田浩平, 笠井飛鳥, 酒井陽子, 堤保夫, 田中克哉 : 高齢者におけるレミフェンタニル麻酔と糖負荷が代謝に与える影響, 日本麻酔科学会第64回学術集会, 2017年6月.

科学研究費補助金 (KAKEN Grants Database @ NII.ac.jp)

吸入麻酔薬とサーチュインの心筋保護作用とオートファジーの役割 (研究課題/領域番号: 19K18244 )
吸入麻酔薬の心筋保護作用がミトコンドリアダイナミクスに与える影響 (研究課題/領域番号: 17K16735 )
吸入麻酔薬とGLP-1の心筋保護相互作用とオートファジーの役割 (研究課題/領域番号: 15H06448 )
研究者番号（90756892）による検索