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Tokushima UniversityGraduate School of Biomedical Sciences医学域先端医学教育研究プロジェクト
Tokushima UniversityGraduate School of Biomedical Sciences医学域Medical SciencePhysiological SciencesDepartment of Pharmacology
Tokushima UniversityResearch ClustersResearch Clusters (Registered)2104018 徳島の特産品(藍,スダチ)の,薬用および産業資源としての活用を志向した基礎研究
Tokushima UniversityGraduate School of MedicineMedicineCourse of Biological Medicine
Tokushima UniversityFaculty of MedicineSchool of MedicineCourse of Biological MedicinePharmacology
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Life sciences [Pharmacology]
Life sciences [Cardiology]
Life sciences [Molecular biology]

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Book / Paper

Academic Paper (Judged Full Paper):

1. Steeve Akumwami, Asadur Rahman, Masafumi Funamoto, Akram Hossain, Asahiro Morishita, Yasumasa Ikeda, Hiroaki Kitamura, Kento Kitada, Takahisa Noma, Yuichi Ogino and Akira Nishiyama :
Effects of D-Allose on experimental cardiac hypertrophy.,
Journal of Pharmacological Sciences, Vol.156, No.2, 142-148, 2024.
(DOI: 10.1016/j.jphs.2024.08.002,   PubMed: 39179333)
2. Yasufumi Katanasaka, Harumi Yabe, Noriyuki Murata, Minori Sobukawa, Yuga Sugiyama, Hikaru Sato, Hiroki Honda, Yoichi Sunagawa, Masafumi Funamoto, Satoshi Shimizu, Kana Shimizu, Toshihide Hamabe-Horiike, Philip Hawke, Maki Komiyama, Kiyoshi Mori, Koji Hasegawa and Tatsuya Morimoto :
Fibroblast-specific PRMT5 deficiency suppresses cardiac fibrosis and left ventricular dysfunction in male mice.,
Nature Communications, Vol.15, No.1, 2472, 2024.
(DOI: 10.1038/s41467-024-46711-z,   PubMed: 38503742)
3. Yoichi Sunagawa, Ryosuke Tsukabe, Yudai Irokawa, Masafumi Funamoto, Yuto Suzuki, Miho Yamada, Satoshi Shimizu, Yasufumi Katanasaka, Toshihide Hamabe-Horiike, Yuto Kawase, Ryuya Naruta, Kana Shimizu, Kiyoshi Mori, Ryota Hosomi, Maki Komiyama, Koji Hasegawa and Tatsuya Morimoto :
Anserine, a Histidine-Containing Dipeptide, Suppresses Pressure Overload-Induced Systolic Dysfunction by Inhibiting Histone Acetyltransferase Activity of p300 in Mice.,
International Journal of Molecular Sciences, Vol.25, No.4, 2344, 2024.
(Tokushima University Institutional Repository: 119246,   DOI: 10.3390/ijms25042344,   PubMed: 38397020)
4. Xi Chen, Asadur Rahman, Steeve Akumwami, Asahiro Morishita, Kento Kitada, Yasumasa Ikeda, Masafumi Funamoto and Akira Nishiyama :
Effects of D-allose on ATP production and cell viability in neonatal rat cardiomyocytes.,
Journal of Pharmacological Sciences, Vol.154, No.4, 274-278, 2024.
(DOI: 10.1016/j.jphs.2024.02.009,   PubMed: 38485345)
5. Honoka Tsunematsu, Masaki Imanishi, Yuka Uemura, Yoshiya Higaki, Miyu Morisaki, Akari Katsura, Licht Miyamoto, Masafumi Funamoto, Mayuko Ichimura-Shimizu, Yuya Horinouchi, Yasumasa Ikeda, Koichi Tsuneyama and Koichiro Tsuchiya :
Indigo Leaves-Induced Pulmonary Arterial Remodeling without Right Ventricular Hypertrophy in Rats.,
Biological & Pharmaceutical Bulletin, Vol.47, No.7, 1350-1359, 2024.
(DOI: 10.1248/bpb.b24-00289,   PubMed: 39085074,   CiNii: 1390863937794660096,   Elsevier: Scopus)
6. Swati Mittal, Maki Komiyama, Yuka Ozaki, Hajime Yamakage, Noriko Satoh-Asahara, Hiromichi Wada, Akihiro Yasoda, Masafumi Funamoto, Yasufumi Katanasaka, Yoichi Sunagawa, Tatsuya Morimoto, Masaharu Akao, Mitsuru Abe, Yuko Takahashi, Takeo Nakayama and Koji Hasegawa :
Impact of smoking initiation age on nicotine dependency and cardiovascular risk factors: a retrospective cohort study in Japan.,
European Heart Journal Open, Vol.4, No.1, 2023.
(DOI: 10.1093/ehjopen/oead135,   PubMed: 38250139)
7. Masaki Imanishi, Takahisa Inoue, Keijo Fukushima, Ryosuke Yamashita, Ryo Nakayama, Masataka Nojima, Kosuke Kondo, Yoshiki Gomi, Honoka Tsunematsu, Kohei Goto, Licht Miyamoto, Masafumi Funamoto, Masaya Denda, Keisuke Ishizawa, Akira Otaka, Hiromichi Fujino, Yasumasa Ikeda and Koichiro Tsuchiya :
CA9 and PRELID2; hypoxia-responsive potential therapeutic targets for pancreatic ductal adenocarcinoma as per bioinformatics analyses.,
Journal of Pharmacological Sciences, Vol.153, No.4, 232-242, 2023.
(Tokushima University Institutional Repository: 119176,   DOI: 10.1016/j.jphs.2023.10.003,   PubMed: 37973221,   CiNii: 1050018428980929664)
8. Aoi Suenaga, Yasuyuki Seto, Masafumi Funamoto, Masaki Imanishi, Koichiro Tsuchiya and Yasumasa Ikeda :
TJ-17 (Goreisan) mitigates renal fibrosis in a mouse model of folic acid-induced chronic kidney disease.,
Journal of Pharmacological Sciences, Vol.153, No.1, 31-37, 2023.
(Tokushima University Institutional Repository: 118452,   DOI: 10.1016/j.jphs.2023.07.001,   PubMed: 37524452)
9. Yuto Kawase, Yoichi Sunagawa, Kana Shimizu, Masafumi Funamoto, Toshihide Hamabe-Horiike, Yasufumi Katanasaka, Satoshi Shimizu, Philip Hawke, Kiyoshi Mori, Maki Komiyama, Koji Hasegawa and Tatsuya Morimoto :
6-Shogaol, an Active Component of Ginger, Inhibits p300 Histone Acetyltransferase Activity and Attenuates the Development of Pressure-Overload-Induced Heart Failure.,
Nutrients, Vol.15, No.9, 2232, 2023.
(DOI: 10.3390/nu15092232,   PubMed: 37432400)
10. Yoichi Sunagawa, Shogo Kawaguchi, Yusuke Miyazaki, Yasufumi Katanasaka, Masafumi Funamoto, Kana Shimizu, Satoshi Shimizu, Toshihide Hamabe-Horiike, Yuto Kawase, Maki Komiyama, Kiyoshi Mori, Akira Murakami, Koji Hasegawa and Tatsuya Morimoto :
Auraptene, a citrus peel-derived natural product, prevents myocardial infarction-induced heart failure by activating PPARα in rats.,
Phytomedicine, Vol.107, 154457, 2022.
(DOI: 10.1016/j.phymed.2022.154457,   PubMed: 36223697)
11. Masafumi Funamoto, Yoichi Sunagawa, Yasufumi Katanasaka, Toru Kato, Junichi Funada, Yoichi Ajiro, Maki Komiyama, Masaharu Akao, Akihiro Yasoda, Hajime Yamakage, Noriko Satoh-Asahara, Hiromichi Wada, Yasumasa Ikeda, Tatsuya Morimoto and Koji Hasegawa :
Effects of high-absorption curcumin for the prevention of hypertensive heart disease: a double-blind, placebo-controlled, randomized clinical study.,
European Heart Journal Open, Vol.107, 154457, 2022.
(Tokushima University Institutional Repository: 118447,   DOI: 10.1093/ehjopen/oeac057,   PubMed: 36172003)
12. Masafumi Funamoto, Yoichi Sunagawa, Mai Gempei, Kana Shimizu, Yasufumi Katanasaka, Satoshi Shimizu, Toshihide Hamabe-Horiike, Giovanni Appendino, Alberto Minassi, Andreas Koeberle, Maki Komiyama, Kiyoshi Mori, Koji Hasegawa and Tatsuya Morimoto :
Pyrazole-Curcumin Suppresses Cardiomyocyte Hypertrophy by Disrupting the CDK9/CyclinT1 Complex.,
Pharmaceutics, Vol.14, No.6, 1269, 2022.
(Tokushima University Institutional Repository: 118446,   DOI: 10.3390/pharmaceutics14061269,   PubMed: 35745840)
13. Yasumasa Ikeda, Masafumi Funamoto, Seiji Kishi, Masaki Imanishi, Ken-ichi Aihara, Yoshiki Kashiwada and Koichiro Tsuchiya :
The novel preventive effect of a Japanese ethical Kampo extract formulation TJ-90 (Seihaito) against cisplatin-induced nephrotoxicity,
Phytomedicine, Vol.103, No.8, 154213, 2022.
(Tokushima University Institutional Repository: 117134,   DOI: 10.1016/j.phymed.2022.154213)
14. Yoichi Sunagawa, Ayumi Katayama, Masafumi Funamoto, Kana Shimizu, Satoshi Shimizu, Nurmila Sari, Yasufumi Katanasaka, Yusuke Miyazaki, Ryota Hosomi, Koji Hasegawa and Tatsuya Morimoto :
The polyunsaturated fatty acids, EPA and DHA, ameliorate myocardial infarction-induced heart failure by inhibiting p300-HAT activity in rats.,
The Journal of Nutritional Biochemistry, Vol.106, 109031, 2022.
(DOI: 10.1016/j.jnutbio.2022.109031,   PubMed: 35504444)
15. Yasufumi Katanasaka, Ayumi Saito, Yoichi Sunagawa, Nurmila Sari, Masafumi Funamoto, Satoshi Shimizu, Kana Shimizu, Takehide Akimoto, Chikara Ueki, Mitsuru Kitano, Koji Hasegawa, Genichi Sakaguchi and Tatsuya Morimoto :
ANGPTL4 Expression Is Increased in Epicardial Adipose Tissue of Patients with Coronary Artery Disease.,
Journal of Clinical Medicine, Vol.11, No.9, 2449, 2022.
(Tokushima University Institutional Repository: 118445,   DOI: 10.3390/jcm11092449,   PubMed: 35566578)
16. Takahiro Katagiri, Yoichi Sunagawa, Tatsuya Maekawa, Masafumi Funamoto, Satoshi Shimizu, Kana Shimizu, Yasufumi Katanasaka, Maki Komiyama, Philip Hawke, Hideo Hara, Kiyoshi Mori, Koji Hasegawa and Tatsuya Morimoto :
Okamura Extract Suppresses Myocardial Infarction-Induced Left Ventricular Systolic Dysfunction by Inhibiting p300-HAT Activity.,
Nutrients, Vol.14, No.3, 580, 2022.
(Tokushima University Institutional Repository: 118443,   DOI: 10.3390/nu14030580,   PubMed: 35276939)
17. Masaya Ono, Yoichi Sunagawa, Saho Mochizuki, Takahiro Katagiri, Hidemichi Takai, Sonoka Iwashimizu, Kyoko Inai, Masafumi Funamoto, Kana Shimizu, Satoshi Shimizu, Yasufumi Katanasaka, Maki Komiyama, Philip Hawke, Hideo Hara, Yoshiki Arakawa, Kiyoshi Mori, Akira Asai, Koji Hasegawa and Tatsuya Morimoto :
Extract Ameliorates Doxorubicin-Induced Cardiotoxicity by Decreasing Apoptosis.,
Cancers, Vol.14, No.3, 683, 2022.
(DOI: 10.3390/cancers14030683,   PubMed: 35158951)
18. Satoshi Shimizu, Yoichi Sunagawa, Naruto Hajika, Natsumi Yorimitsu, Yasufumi Katanasaka, Masafumi Funamoto, Yusuke Miyazaki, Nurmila Sari, Kana Shimizu, Koji Hasegawa and Tatsuya Morimoto :
Multimerization of the GATA4 transcription factor regulates transcriptional activity and cardiomyocyte hypertrophic response.,
International Journal of Biological Sciences, Vol.18, No.3, 1079-1095, 2022.
(DOI: 10.7150/ijbs.65664,   PubMed: 35173540,   CiNii: 1360576118771335168,   Elsevier: Scopus)
19. Kana Shimizu, Yoichi Sunagawa, Masafumi Funamoto, Hiroki Honda, Yasufumi Katanasaka, Noriyuki Murai, Yuto Kawase, Yuta Hirako, Takahiro Katagiri, Harumi Yabe, Satoshi Shimizu, Nurmila Sari, Hiromichi Wada, Koji Hasegawa and Tatsuya Morimoto :
The Selective Serotonin 2A Receptor Antagonist Sarpogrelate Prevents Cardiac Hypertrophy and Systolic Dysfunction via Inhibition of the ERK1/2-GATA4 Signaling Pathway,
Pharmaceuticals, Vol.14, No.12, 1268, 2021.
(DOI: 10.3390/ph14121268,   PubMed: 34959669,   Elsevier: Scopus)
20. Yasufumi Katanasaka, Naoki Yoshida, Hirotaka Naitou, Ryuya Naruta, Yusuke Miyazaki, Yoichi Sunagawa, Masafumi Funamoto, Kana Shimizu, Satoshi Shimizu, Numila Sari, Hajime Yamakage, Noriko Satoh-Asahara, Koji Hasegawa and Tatsuya Morimoto :
Effect of Theaflavin on Oral Bacteria in Japanese Subjects: A Randomized, Placebo-Controlled, Double-Blind Study.,
Journal of Medicinal Food, Vol.24, No.11, 1186-1190, 2021.
(DOI: 10.1089/jmf.2021.K.0050,   PubMed: 34698557)
21. Nurmila Sari, Yasufumi Katanasaka, Yuga Sugiyama, Yoichi Sunagawa, Yusuke Miyazaki, Masafumi Funamoto, Satoshi Shimizu, Kana Shimizu, Akira Murakami, Kiyoshi Mori, Hiromichi Wada, Koji Hasegawa and Tatsuya Morimoto :
Zerumbone prevents pressure overload-induced left ventricular systolic dysfunction by inhibiting cardiac hypertrophy and fibrosis.,
Phytomedicine, Vol.92, 153744, 2021.
(DOI: 10.1016/j.phymed.2021.153744,   PubMed: 34563985)
22. Yoichi Sunagawa, Masafumi Funamoto, Kana Shimizu, Satoshi Shimizu, Nurmila Sari, Yasufumi Katanasaka, Yusuke Miyazaki, Hideaki Kakeya, Koji Hasegawa and Tatsuya Morimoto :
Curcumin, an Inhibitor of p300-HAT Activity, Suppresses the Development of Hypertension-Induced Left Ventricular Hypertrophy with Preserved Ejection Fraction in Dahl Rats.,
Nutrients, Vol.13, No.8, 2608, 2021.
(DOI: 10.3390/nu13082608,   PubMed: 34444769)
23. Yoichi Sunagawa, Kiyotaka Shimizu, Ayumi Katayama, Masafumi Funamoto, Kana Shimizu, Sari Nurmila, Satoshi Shimizu, Yusuke Miyazaki, Yasufumi Katanasaka, Koji Hasegawa and Tatsuya Morimoto :
Metformin suppresses phenylephrine-induced hypertrophic responses by inhibiting p300-HAT activity in cardiomyocytes.,
Journal of Pharmacological Sciences, Vol.147, No.2, 169-175, 2021.
(DOI: 10.1016/j.jphs.2021.07.001,   PubMed: 34384564)
24. Maki Komiyama, Yuka Ozaki, Yusuke Miyazaki, Yasufumi Katanasaka, Yoichi Sunagawa, Masafumi Funamoto, Kana Shimizu, Hajime Yamakage, Noriko Sato-Asahara, Akihiro Yasoda, Hiromichi Wada, Tatsuya Morimoto and Koji Hasegawa :
Neutrophil/lymphocyte ratio is correlated with levels of inflammatory markers and is significantly reduced by smoking cessation.,
The Journal of International Medical Research, Vol.49, No.6, 3000605211019223, 2021.
(DOI: 10.1177/03000605211019223,   PubMed: 34187206)
25. Swati Mittal, Maki Komiyama, Yuka Ozaki, Hajime Yamakage, Noriko Satoh-Asahara, Akihiro Yasoda, Hiromichi Wada, Masafumi Funamoto, Kana Shimizu, Yusuke Miyazaki, Yasufumi Katanasaka, Yoichi Sunagawa, Tatsuya Morimoto, Yuko Takahashi, Takeo Nakayama and Koji Hasegawa :
Gingival bleeding and pocket depth among smokers and the related changes after short-term smoking cessation,
Acta Odontologica Scandinavica, Vol.80, No.4, 258-263, 2021.
(Tokushima University Institutional Repository: 118442,   DOI: 10.1080/00016357.2021.1995040,   PubMed: 34893003,   Elsevier: Scopus)
26. Masafumi Funamoto, Yoichi Sunagawa, Yasufumi Katanasaka, Kana Shimizu, Yusuke Miyazaki, Nurmila Sari, Satoshi Shimizu, Kiyoshi Mori, Hiromichi Wada, Koji Hasegawa and Tatsuya Morimoto :
Histone Acetylation Domains Are Differentially Induced during Development of Heart Failure in Dahl Salt-Sensitive Rats,
International Journal of Molecular Sciences, Vol.22, No.4, 1771, 2021.
(DOI: 10.3390/ijms22041771,   PubMed: 33578969,   Elsevier: Scopus)
27. Yasufumi Katanasaka, Sae Hirano, Yoichi Sunagawa, Yusuke Miyazaki, Hikaru Sato, Masafumi Funamoto, Kana Shimizu, Satoshi Shimizu, Nurmila Sari, Koji Hasegawa and Tatsuya Morimoto :
Clinically Administered Doses of Pitavastatin and Rosuvastatin.,
International Heart Journal, Vol.62, No.6, 1379-1386, 2021.
(DOI: 10.1536/ihj.21-231,   PubMed: 34853228)
28. Nurmila Sari, Yasufumi Katanasaka, Yuga Sugiyama, Yusuke Miyazaki, Yoichi Sunagawa, Masafumi Funamoto, Kana Shimizu, Satoshi Shimizu, Koji Hasegawa and Tatsuya Morimoto :
Alpha Mangostin Derived from Garcinia magostana Linn Ameliorates Cardiomyocyte Hypertrophy and Fibroblast Phenotypes in Vitro.,
Biological & Pharmaceutical Bulletin, Vol.44, No.10, 1465-1472, 2021.
(DOI: 10.1248/bpb.b21-00294,   PubMed: 34602555)
29. Nurmila Sari, Yasufumi Katanasaka, Hiroki Honda, Yusuke Miyazaki, Yoichi Sunagawa, Masafumi Funamoto, Kana Shimizu, Satoshi Shimizu, Hiromichi Wada, Koji Hasegawa and Tatsuya Morimoto :
Cacao Bean Polyphenols Inhibit Cardiac Hypertrophy and Systolic Dysfunction in Pressure Overload-induced Heart Failure Model Mice.,
Planta Medica, Vol.86, No.17, 1304-1312, 2020.
(DOI: 10.1055/a-1191-7970,   PubMed: 32645737)
30. Kana Shimizu, Yoichi Sunagawa, Masafumi Funamoto, Hiroki Wakabayashi, Mai Genpei, Yusuke Miyazaki, Yasufumi Katanasaka, Nurmila Sari, Satoshi Shimizu, Ayumi Katayama, Hiroyuki Shibata, Yoshiharu Iwabuchi, Hideaki Kakeya, Hiromichi Wada, Koji Hasegawa and Tatsuya Morimoto :
The Synthetic Curcumin Analogue GO-Y030 Effectively Suppresses the Development of Pressure Overload-induced Heart Failure in Mice.,
Scientific Reports, Vol.10, No.1, 7172, 2020.
(DOI: 10.1038/s41598-020-64207-w,   PubMed: 32346115)
31. Yasufumi Katanasaka, Yusuke Miyazaki, Yoichi Sunagawa, Masafumi Funamoto, Kana Shimizu, Satoshi Shimizu, Nurmila Sari, Yasuo Shimizu, Hiromichi Wada, Koji Hasegawa and Tatsuya Morimoto :
Kosen-cha, a Polymerized Catechin-Rich Green Tea, as a Potential Functional Beverage for the Reduction of Body Weight and Cardiovascular Risk Factors: A Pilot Study in Obese Patients.,
Biological & Pharmaceutical Bulletin, Vol.43, No.4, 675-681, 2020.
(DOI: 10.1248/bpb.b19-00921,   PubMed: 32238708)
32. Masafumi Funamoto, Kana Shimizu, Yoichi Sunagawa, Yasufumi Katanasaka, Yusuke Miyazaki, Maki Komiyama, Hajime Yamakage, Noriko Satoh-Asahara, Yuko Takahashi, Hiromichi Wada, Koji Hasegawa and Tatsuya Morimoto :
Serum Cystatin C, a Sensitive Marker of Renal Function and Cardiovascular Disease, Decreases After Smoking Cessation.,
Circulation Reports, Vol.1, No.12, 623-627, 2019.
(DOI: 10.1253/circrep.CR-19-0052,   PubMed: 33693109)
33. Masafumi Funamoto, Kana Shimizu, Yoichi Sunagawa, Yasufumi Katanasaka, Yusuke Miyazaki, Hideaki Kakeya, Hajime Yamakage, Noriko Satoh-Asahara, Hiromichi Wada, Koji Hasegawa and Tatsuya Morimoto :
Effects of Highly Absorbable Curcumin in Patients with Impaired Glucose Tolerance and Non-Insulin-Dependent Diabetes Mellitus.,
Journal of Diabetes Research, Vol.2019, 8208237, 2019.
(DOI: 10.1155/2019/8208237,   PubMed: 31871950)
34. Yoichi Sunagawa, Masafumi Funamoto, Shogo Sono, Kana Shimizu, Satoshi Shimizu, Mai Genpei, Yusuke Miyazaki, Yasufumi Katanasaka, Eriko Morimoto, Morio Ueno, Maki Komiyama, Hideaki Kakeya, Hiromichi Wada, Koji Hasegawa and Tatsuya Morimoto :
Curcumin and its demethoxy derivatives possess p300 HAT inhibitory activity and suppress hypertrophic responses in cardiomyocytes.,
Journal of Pharmacological Sciences, Vol.136, No.4, 212-217, 2018.
(DOI: 10.1016/j.jphs.2017.12.013,   PubMed: 29602708)
35. Yoichi Sunagawa, Nobuko Okamura, Yusuke Miyazaki, Kana Shimizu, Mai Genpei, Masafumi Funamoto, Satoshi Shimizu, Yasufumi Katanasaka, Eriko Morimoto, Hajime Yamakage, Maki Komiyama, Noriko Satoh-Asahara, Hiromichi Wada, Mika Suzuki, Koji Hasegawa and Tatsuya Morimoto :
Effects of Products Containing Bacillus subtilis var. natto on Healthy Subjects with Neck and Shoulder Stiffness, a Double-Blind, Placebo-Controlled, Randomized Crossover Study.,
Biological & Pharmaceutical Bulletin, Vol.41, No.4, 504-509, 2018.
(DOI: 10.1248/bpb.b17-00780,   PubMed: 29415906)
36. Yusuke Miyazaki, Yasufumi Katanasaka, Yoichi Sunagawa, Sae Hirano-Sunagawa, Masafumi Funamoto, Eriko Morimoto, Maki Komiyama, Akira Shimatsu, Noriko Satoh-Asahara, Hajime Yamakage, Hiromichi Wada, Koji Hasegawa and Tatsuya Morimoto :
Effect of statins on atherogenic serum amyloid A and α1-antitrypsin low-density lipoprotein complexes.,
International Journal of Cardiology, Vol.225, 332-336, 2016.
(DOI: 10.1016/j.ijcard.2016.09.116,   PubMed: 27756037)
37. Masafumi Funamoto, Yoichi Sunagawa, Yasufumi Katanasaka, Yusuke Miyazaki, Atsushi Imaizumi, Hideaki Kakeya, Hajime Yamakage, Noriko Satoh-Asahara, Maki Komiyama, Hiromichi Wada, Koji Hasegawa and Tatsuya Morimoto :
Highly absorptive curcumin reduces serum atherosclerotic low-density lipoprotein levels in patients with mild COPD.,
International Journal of Chronic Obstructive Pulmonary Disease, Vol.11, 2029-2034, 2016.
(DOI: 10.2147/COPD.S104490,   PubMed: 27616885)
38. Hidetoshi Suzuki, Yasufumi Katanasaka, Yoichi Sunagawa, Yusuke Miyazaki, Masafumi Funamoto, Hiromichi Wada, Koji Hasegawa and Tatsuya Morimoto :
Tyrosine phosphorylation of RACK1 triggers cardiomyocyte hypertrophy by regulating the interaction between p300 and GATA4.,
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, Vol.1862, No.9, 1544-1557, 2016.
(DOI: 10.1016/j.bbadis.2016.05.006,   PubMed: 27208796)
39. Yoichi Sunagawa, Sae Hirano, Yasufumi Katanasaka, Yusuke Miyazaki, Masafumi Funamoto, Nobuko Okamura, Yuya Hojo, Hidetoshi Suzuki, Osamu Doi, Tsunehiro Yokoji, Eriko Morimoto, Tsukasa Takashi, Hitomi Ozawa, Atsushi Imaizumi, Morio Ueno, Hideaki Kakeya, Akira Shimatsu, Hiromichi Wada, Koji Hasegawa and Tatsuya Morimoto :
Colloidal submicron-particle curcumin exhibits high absorption efficiency-a double-blind, 3-way crossover study.,
Journal of Nutritional Science and Vitaminology, Vol.61, No.1, 37-44, 2015.
(DOI: 10.3177/jnsv.61.37,   PubMed: 25994138)
40. Tatsuya Morimoto, Yasufumi Katanasaka, Yoichi Sunagawa, Sae Hirano, Yusuke Miyazaki, Masafumi Funamoto, Yuya Hojo, Hidetoshi Suzuki, Eriko Morimoto, Morio Ueno, Akira Shimatsu, Noriko Satoh-Asahara, Hajime Yamakage, Hiromichi Wada and Koji Hasegawa :
Effects of Statins on Left Ventricular Diastolic Function in Patients with Dyslipidemia and Diastolic Dysfunction (Stat-LVDF Study).,
Biological & Pharmaceutical Bulletin, Vol.38, No.9, 1404-1409, 2015.
(DOI: 10.1248/bpb.b15-00126,   PubMed: 26328497)
41. Yoichi Sunagawa, Shogo Sono, Yasufumi Katanasaka, Masafumi Funamoto, Sae Hirano, Yusuke Miyazaki, Yuya Hojo, Hidetoshi Suzuki, Eriko Morimoto, Akira Marui, Ryuzo Sakata, Morio Ueno, Hideaki Kakeya, Hiromichi Wada, Koji Hasegawa and Tatsuya Morimoto :
Optimal dose-setting study of curcumin for improvement of left ventricular systolic function after myocardial infarction in rats.,
Journal of Pharmacological Sciences, Vol.126, No.4, 329-336, 2014.
(DOI: 10.1254/jphs.14151FP,   PubMed: 25409899)

Review, Commentary:

1. Yasumasa Ikeda, Masafumi Funamoto and 山本 みずほ :
腎性貧血の新規治療標的 ヘプシジンとエリスロフェロン(今この研究が面白い!2024年9月増大号),
臨床雑誌内科, Vol.134, No.3, 788-791, Sep. 2024.
2. Yasumasa Ikeda and Masafumi Funamoto :
[A new attempt of integrated practice of basic medicine in Tokushima University].,
Folia Pharmacologica Japonica, Vol.158, No.6, 440-443, Nov. 2023.
(DOI: 10.1254/fpj.23017,   PubMed: 37914318)
3. Masafumi Funamoto and Yasumasa Ikeda :
The association between COVID-19 and cardiovascular diseases,
Shikoku Acta Medica, Vol.79, No.1,2, 37-42, Jun. 2023.
(Tokushima University Institutional Repository: 118415,   DOI: 10.57444/shikokuactamedica.79.1.2_37,   CiNii: 1390015191534393344)
4. Masafumi Funamoto, Masaki Imanishi, Koichiro Tsuchiya and Yasumasa Ikeda :
Roles of histone acetylation sites in cardiac hypertrophy and heart failure.,
Frontiers in Cardiovascular Medicine, Vol.10, Mar. 2023.
(DOI: 10.3389/fcvm.2023.1133611,   PubMed: 37008337)
5. Yasumasa Ikeda, Masafumi Funamoto and Koichiro Tsuchiya :
The role of iron in obesity and diabetes.,
The Journal of Medical Investigation : JMI, Vol.69, No.1.2, 1-7, Apr. 2022.
(Tokushima University Institutional Repository: 116403,   DOI: 10.2152/jmi.69.1,   PubMed: 35466128)
6. Kana Shimizu, Masafumi Funamoto, Yoichi Sunagawa, Satoshi Shimizu, Yasufumi Katanasaka, Yusuke Miyazaki, Hiromichi Wada, Koji Hasegawa and Tatsuya Morimoto :
Anti-inflammatory Action of Curcumin and Its Use in the Treatment of Lifestyle-related Diseases.,
European Cardiology, Vol.14, No.2, 117-122, Jul. 2019.
(DOI: 10.15420/ecr.2019.17.2,   PubMed: 31360234)
7. Tatsuya Morimoto, Masafumi Funamoto, Yoichi Sunagawa, Yasufumi Katanasaka, Yusuke Miyazaki and Koji Hasegawa :
[Noble Heart Failure Therapy Using Food Compositions].,
Journal of the Pharmaceutical Society of Japan, Vol.138, No.10, 1263-1269, 2018.
(DOI: 10.1248/yakushi.18-00091-2,   PubMed: 30270270)

Proceeding of International Conference:

1. Amiho Muramatsu, Masafumi Funamoto, Miyako Ueno, Masaki Imanishi, Yasumasa Ikeda and Koichiro Tsuchiya :
Kampo medicine, orengedokuto, suppresses Doxorubicin-induced cardiotoxicity,
28th International Society of Cardiovascular Pharmacotherapy Annual Scientific Meeting, Nov. 2023.
2. Masafumi Funamoto, Yoichi Sunagawa, Yasufumi Katanasaka, Toru Kato, Yoichi Ajiro, Maki Komiyama, Masaharu Akao, Hajime Yamakage, Noriko Satoh-Asahara, Hiromichi Wada, Yasumasa Ikeda, Tatsuya Morimoto and Koji Hasegawa :
Effects of high-absorption curcumin for the prevention of hypertensive heart disease,
28th International Society of Cardiovascular Pharmacotherapy Annual Scientific Meeting, Nov. 2023.
3. Masafumi Funamoto, Yoichi Sunagawa, Yasufumi Katanasaka, Maki Komiyama, Masaharu Akao, Akihiro Yasoda, Hajime Yamakage, Noriko Satoh-Asahara, Hiromichi Wada, Yasumasa Ikeda, Tatsuya Morimoto and Koji Hasegawa :
Clinical trial for high-absorption curcumin, targeting p300-histonetransferase activity, in patients with hypertensive heart disease,
27TH ASIAN PACIFIC SOCIETY OF CARDIOLOGY CONGRESS, Jul. 2023.
4. Masafumi Funamoto, Yoichi Sunagawa, Yasufumi Katanasaka, Hajime Yamakage, Noriko Satoh-Asahara, Maki Komiyama, Hiromichi Wada, Koji Hasegawa and Tatsuya Morimoto :
High absorption curcumin reduces serum atherosclerotic low density lipoprotein levels in patients with mild COPD,
27TH ASIAN PACIFIC SOCIETY OF CARDIOLOGY CONGRESS, Jul. 2023.
5. Yuto Kawase, Kana Shimizu, Masafumi Funamoto, Yoichi Sunagawa, Yasufumi Katanasaka, Yusuke Miyazaki, Satoshi Shimizu, Koji Hasegawa and Tatuya Morimoto :
Young Investigator Award: Compound A, a Ginger Extract, Significantly Reduces Pressure Overload-induced Systolic Heart Failure in Mice.,
European Cardiology, Vol.16, e57, Dec. 2021.
(DOI: 10.15420/ecr.2021.16.PO1,   PubMed: 35106073)
6. Satoshi Shimizu, Miho Yamada, Takahiro Katagiri, Yoichi Sunagawa, Yasufumi Katanasaka, Yusuke Miyazaki, Masafumi Funamoto, Sari Nurmila, Kana Shimizu, Naohisa Ogo, Akira Asai, Koji Hasegawa and Tatsuya Morimoto :
Discovery of Novel Small Molecules for Heart Failure Therapy Using Cultured Cardiomyocyte by High Throughput Screening Assay.,
European Cardiology, Vol.16, e66, Dec. 2021.
(DOI: 10.15420/ecr.2021.16.PO10,   PubMed: 35106082)
7. Yoichi Sunagawa, Ayumi Katayama, Masafumi Funamoto, Kana Shimizu, Satoshi Shimizu, Yasufumi Katanasaka, Yusuke Miyazaki, Koji Hasegawa and Tatsuya Morimoto :
The Polyunsaturated Fatty Acids EPA and DHA Prevent Myocardial Infarction-induced Heart Failure by Inhibiting p300-HAT Activity in Rats.,
European Cardiology, Vol.16, e68, Dec. 2021.
(DOI: 10.15420/ecr.2021.16.PO12,   PubMed: 35106084)
8. Hidemichi Takai, Yoichi Sunagawa, Masafumi Funamoto, Kana Shimizu, Satoshi Shimizu, Yasufumi Katanasaka, Yusuke Miyazaki, Atsusi Imaizumi, Tadashi Hashimoto, Hiromichi Wada, Koji Hasegawa and Tatsuya Morimoto :
A Novel Curcumin Formulation, ASD-Cur, Suppressed the Development of Systolic Dysfunction After Myocardial Infarction in Rats.,
European Cardiology, Vol.16, e69, Dec. 2021.
(DOI: 10.15420/ecr.2021.16.PO13,   PubMed: 35106085)
9. Mai Genpei, Yoichi Sunagawa, Masafumi Funamoto, Kana Shimizu, Yusuke Miyazaki, Yasufumi Katanasaka, Nobuaki Takahashi, Hideaki Kakeya, Hiromichi Wada, Koji Hasegawa and Tatsuya Morimoto :
Erratum to: The Inhibitory Effects of Crucumin Glucuronide on p300-HAT Activity and Hypertrophic Phenylephrine-Induced Responses in Cardiomyocytes.,
European Cardiology, Vol.13, No.2, 136, Dec. 2018.
(DOI: 10.15420/ecr.2018.13.2.ER1,   PubMed: 30697358)
10. Yoichi Sunagawa, Masafumi Funamoto, Anna Suzuki, Kana Shimizu, Ryoga Sakurai, Yasufumi Katanasaka, Yusuke Miyazaki, Tomohiro Asakawa, Toshiyuki Kan, Junya Inagaki, Hiromichi Wada, Koji Hasegawa and Tatsuya Morimoto :
A Novel Target Molecule of Nobiletin Derived from Citrus Peels has a Therapeutic Potency Against the Development of Heart Failure.,
European Cardiology, Vol.12, No.2, 105, Dec. 2017.
(DOI: 10.15420/ecr.2017:23:14,   PubMed: 30416575)
11. Kana Shimizu, Masafumi Funamoto, Mai Genpei, Yoichi Sunagawa, Yasufumi Katanasaka, Yusuke Miyazaki, Hiroyuki Shibata, Hiromichi Wada, Koji Hasegawa and Tatsuya Morimoto :
Curcumin Analogue GO-Y030 Significantly Improves Pressure Overload-induced Heart Failure in Vivo.,
European Cardiology, Vol.12, No.2, 106, Dec. 2017.
(DOI: 10.15420/ecr.2017:23:15,   PubMed: 30416576)
12. Mai Genpei, Yoichi Sunagawa, Masafumi Funamoto, Kana Shimizu, Yusuke Miyazaki, Yasufumi Katanasaka, Nobuaki Takahashi, Hideaki Kakeya, Hiromichi Wada, Koji Hasegawa and Tatsuya Morimoto :
The Inhibitory Effects of Crucumin Glucuronide on p300-HAT Activity and Hypertrophic Phenylephrine-Induced Responses in Cardiomyocytes.,
European Cardiology, Vol.12, No.2, 107, Dec. 2017.
(DOI: 10.15420/ecr.2017:23:16,   PubMed: 30416577)

Proceeding of Domestic Conference:

1. Masafumi Funamoto, Amiho Muramatsu, YAMAMOTO Mizuho, Shunji Hirose, Masaki Imanishi, Koichiro Tsuchiya and Yasumasa Ikeda :
黄連解毒湯によるドキソルビシン誘導性心毒性に対する効果検討,
第8回黒潮カンファレンス, Sep. 2024.
2. YAMAMOTO Mizuho, Masafumi Funamoto, 上原 渉, 眞鍋 智弘, 砂川 陽一, 刀坂 泰史, 浜辺 俊秀, 川瀬 裕斗, 鳴田 竜也, 小見山 麻紀, 長谷川 浩二, Yasumasa Ikeda and 森本 達也 :
p300/CBPのヒストンアセチル化酵素活性を阻害する低分子化合物であるA485は圧負荷による収縮機能低下を改善した,
第8回黒潮カンファレンス, Sep. 2024.
3. Shunji Hirose, Masafumi Funamoto, YAMAMOTO Mizuho, Masaki Imanishi, Yasumasa Ikeda and Koichiro Tsuchiya :
糖尿病性心筋症に対する漢方薬五苓散の抑制効果,
第8回黒潮カンファレンス, Sep. 2024.
4. 前田 莉沙, 片桐 宇大, 清水 聡, Masafumi Funamoto, 浜辺 俊秀, 砂川 陽一, 川瀬 裕斗, 鳴田 竜也, 刀坂 泰史, 長谷川 浩二 and 森本 達也 :
High throughput screening assayにより同定したRFN-409は圧負荷による心肥大と左室収縮能低下を抑制した,
第9回日本心血管協会(JCVA)学術集会, 58, May 2024.
5. 中西 俊輔, 高井 秀通, 砂川 陽一, Masafumi Funamoto, 川瀬 裕斗, 鳴田 竜也, 刀坂 泰史, 浜辺 俊秀, 今泉 厚, Yasumasa Ikeda, 橋本 正, 長谷川 浩二 and 森本 達也 :
新規クルクミン製剤であるcurcuRougeTMは心筋梗塞モデルラットにおいて心収縮能の低下を抑制した,
第9回日本心血管協会(JCVA)学術集会, 60, May 2024.
6. 眞鍋 智弘, 上原 渉, Masafumi Funamoto, 山本 みずほ, 砂川 陽一, 刀坂 泰史, 浜辺 俊秀, 川瀬 裕斗, 鳴田 竜也, Yasumasa Ikeda, 長谷川 浩二 and 森本 達也 :
圧負荷心不全モデルマウスにおいてBRG1阻害剤PFI-3は心収縮機能悪化を改善した,
第9回日本心血管協会(JCVA)学術集会, 61, May 2024.
7. 稲井 恭子, 岩清水 苑夏, 望月 沙穂, 槌谷 佳那子, 小野 雅也, 砂川 陽一, Masafumi Funamoto, 川瀬 裕斗, 鳴田 竜也, 刀坂 泰史, 浜辺 俊英, 小見山 麻紀, 長谷川 浩二, 坂本 多穂, 黒川 洵子 and 森本 達也 :
ノビレチンはドキソルビシン誘発心毒性に対する保護効果を示した,
第9回日本心血管協会(JCVA)学術集会, 63, May 2024.
8. 品川 統也, 平子 裕太, 清水 果奈, Masafumi Funamoto, 川瀬 裕斗, 鳴田 竜也, 砂川 陽一, 刀坂 泰史, 浜辺 俊英, 清水 聡, 柴田 浩行, 小見山 麻紀, 長谷川 浩二 and 森本 達也 :
クルクミン誘導体GO-Y022はクルクミンより低用量でマウスの圧負荷心不全を改善する,
第9回日本心血管協会(JCVA)学術集会, 67, May 2024.
9. 峯岸 龍志, 砂川 陽一, 石間 彩花, 鈴木 悠斗, 浜辺 俊英, 刀坂 泰史, Masafumi Funamoto, 清水 聡, 長谷川 浩二 and 森本 達也 :
線維芽細胞特異的p300-BP1KOマウスは圧負荷による心線維化及び心筋肥大を抑制した,
第9回日本心血管協会(JCVA)学術集会, 67, May 2024.
10. 須藤 優, 塚部 凌輔, 川瀬 裕斗, 清水 聡, 浜辺 俊英, 砂川 陽一, Masafumi Funamoto, 清水 果奈, 鳴田 竜也, 刀坂 泰史, 長谷川 浩二 and 森本 達也 :
転写因子GATA4の二量体形成が心筋細胞肥大反応を制御する,
第9回日本心血管協会(JCVA)学術集会, 68, May 2024.
11. 髙橋 寧音, 川瀬 裕斗, 平子 裕太, 砂川 陽一, 浜辺 俊英, 刀坂 泰史, 鳴田 竜也, Masafumi Funamoto, 小見山 麻紀, 長谷川 浩二 and 森本 達也 :
天然物サンショウ抽出物Compound Xは圧負荷による心筋肥大や心機能低下を改善させた,
第9回日本心血管協会(JCVA)学術集会, 68, May 2024.
12. 鈴木 悠斗, 砂川 陽一, Masafumi Funamoto, 石間 彩花, 川瀬 裕斗, 浜辺 俊英, 刀坂 泰史, Masafumi Funamoto, 清水 聡, 長谷川 浩二 and 森本 達也 :
心臓特異的p300-BP1ノックアウトは圧負荷による心筋肥大及び心不全の進展を軽減させた,
第9回日本心血管協会(JCVA)学術集会, 69, May 2024.
13. 坂 侑子, 砂川 陽一, Masafumi Funamoto, 前川 達也, 川瀬 裕斗, 鳴田 竜也, 浜辺 俊英, 刀坂 泰史, 長谷川 浩二 and 森本 達也 :
オオイタドリ若芽エキスは心筋梗塞後の心不全の進展を抑制した,
第9回日本心血管協会(JCVA)学術集会, 70, May 2024.
14. 川瀬 裕斗, 清水 果奈, Masafumi Funamoto, 砂川 陽一, 刀坂 泰史, 浜辺 俊英, 清水 聡, 鳴田 竜也, 小見山 麻紀, 長谷川 浩二 and 森本 達也 :
圧負荷心不全モデルマウスにおいて,ショウガ抽出物である6-shogaolは心不全の進行を抑制した,
第9回日本心血管協会(JCVA)学術集会, 70, May 2024.
15. 色川 雄大, 砂川 陽一, 山田 美帆, 片桐 宇大, 前川 健也, 清水 聡, 刀坂 泰史, 浜辺 俊英, 川瀬 裕斗, 鳴田 竜也, Masafumi Funamoto, 清水 果奈, 浅川 倫宏, 長谷川 浩二 and 森本 達也 :
ヒスチジン含有ペプチドであるアンセリンはp300-HAT活性阻害により,心筋細胞肥大および圧負荷モデルマウスの心収縮能低下を抑制した,
第9回日本心血管協会(JCVA)学術集会, 71, May 2024.
16. Mizuho Yamamoto, Masafumi Funamoto, 上原 渉, 眞鍋 智弘, 砂川 陽一, 刀坂 泰史, 浜辺 俊秀, 川瀬 裕斗, 鳴田 竜也, 小見山 麻紀, 長谷川 浩二, Yasumasa Ikeda and 森本 達也 :
低分子化合物A485はp300-HAT阻害作用により圧負荷心不全モデルマウスの心不全悪化を抑制した,
第9回日本心血管協会(JCVA)学術集会, 71, May 2024.
17. Masafumi Funamoto, Amiho Muramatsu, Masaki Imanishi, Hidenori Yasuda, Koichiro Tsuchiya and Yasumasa Ikeda :
アントラサイクリン系抗がん剤による心毒性に対する黄連解毒湯の検討,
第9回日本心血管協会(JCVA)学術集会, 72, May 2024.
18. Shunji Hirose, Masafumi Funamoto, Hidenori Yasuda, Masaki Imanishi, Yasumasa Ikeda and Koichiro Tsuchiya :
糖尿病合併心不全に対する漢方薬五苓散の抑制効果,
第144回日本薬理学会近畿部会, Mar. 2024.
19. Yasumasa Ikeda, Masafumi Funamoto, Hidenori Yasuda, Masaki Imanishi and Koichiro Tsuchiya :
低重力下における消化管と骨髄における鉄動態の検討,
第144回日本薬理学会近畿部会, Mar. 2024.
20. Masafumi Funamoto, Amiho Muramatsu, Masaki Imanishi, Koichiro Tsuchiya and Yasumasa Ikeda :
ドキソルビシン誘導性心毒性を抑制する漢方薬と作用機序の解明,
第53回日本心脈管作動物質学会, Feb. 2024.
21. Masaki Imanishi, Takahisa Inoue, Keijo Fukushima, GOMI Yoshiki, HIGAKI Yoshiya, Masataka Nojima, Kohsuke Kondoh, SAWAMURA Takaya, Ryosuke Yamashita, Ryo Nakayama, Honoka Tsunematsu, GOTOH Kohei, Licht Miyamoto, Masafumi Funamoto, Hiromichi Fujino, Yasumasa Ikeda and Koichiro Tsuchiya :
TCGAがんゲノムビッグデータによる膵がん悪性化因子の網羅的探索と腫瘍血管新生の寄与についての検討,
第53回日本心脈管作動物質学会年会, Feb. 2024.
22. 色川 雄大, 砂川 陽一, 山田 美帆, 片桐 宇大, 前川 健也, 清水 聡史, 刀坂 泰史, 浜辺 俊秀, 川瀬 裕斗, 鳴田 竜也, Masafumi Funamoto, 清水 果奈, 浅川 倫宏, 長谷川 浩二 and 森本 達也 :
ヒスチジン含有ジペプチドであるアンセリンは心筋細胞肥大および 圧負荷モデルマウスの心収縮能低下を抑制した,
第33回日本循環薬理学会, Jan. 2024.
23. 眞鍋 智弘, 上原 渉, Masafumi Funamoto, 山本 みずほ, 砂川 陽一, 刀坂 泰史, 浜辺 俊秀, 川瀬 裕斗, 鳴田 竜也, Yasumasa Ikeda, 長谷川 浩二 and 森本 達也 :
圧負荷心不全モデルマウスにおいて心収縮機能悪化をBRG1阻害剤 PFI-3は抑制した,
第33回循環薬理学会, Jan. 2024.
24. 髙橋 寧音, 川瀬 裕斗, 平子 裕太, 鳴田 竜也, Masafumi Funamoto, 砂川 陽一, 刀坂 泰史, 浜辺 俊秀, 小見山 麻紀, 長谷川 浩二 and 森本 達也 :
天然物サンショウの抽出物であるCompound Xは心機能低下を改善した,
第33回日本循環薬理学会, Jan. 2024.
25. Masafumi Funamoto, Amiho Muramatsu, Masaki Imanishi, Koichiro Tsuchiya and Yasumasa Ikeda :
ドキソルビシン心毒性を抑制する漢方薬と作用機序の解明,
第33回日本循環薬理学会, Jan. 2024.
26. Yasumasa Ikeda, SUENAGA Aoi, SETO Yasuyuki, Masafumi Funamoto, Masaki Imanishi and Koichiro Tsuchiya :
慢性腎臓病に対する漢方薬五苓散の効果の検討,
第97回日本薬理学会年会(神戸), Dec. 2023.
27. Masafumi Funamoto, Amiho Muramatsu, Miyako Ueno, Masaki Imanishi, Koichiro Tsuchiya and Yasumasa Ikeda :
漢方薬のドキソルビシン心毒性に対する効果の検討,
第97回日本薬理学会年会(神戸)2023年12月16日, Dec. 2023.
28. Shunji Hirose, Masafumi Funamoto, Amiho Muramatsu, Miyako Ueno, Masaki Imanishi, Yasumasa Ikeda and Koichiro Tsuchiya :
糖尿病性心筋症におけるエピジェネティック制御機構,
第97回日本薬理学会年会(神戸), Dec. 2023.
29. Masafumi Funamoto :
病的な心肥大におけるマクロファージ鉄ストレスによる心臓老化制御機構の解析,
日本心脈管作動物質学会若手研究者交流シンポジウム, Oct. 2023.
30. Honoka Tsunematsu, Masaki Imanishi, Yuka Uemura, HIGAKI Yoshiya, Keijo Fukushima, Miyu Morisaki, Akari Katsura, Licht Miyamoto, Masafumi Funamoto, Yuya Horinouchi, Yasumasa Ikeda, Hiromichi Fujino, Koichi Tsuneyama and Koichiro Tsuchiya :
藍含有成分はendothelin-1発現を制御して肺動脈血管リモデリングを形成させる,
次世代を担う若手のための創薬・医療薬理シンポジウム2023, Aug. 2023.
31. SAWAMURA Takaya, Masaki Imanishi, Keijo Fukushima, Ryosuke Yamashita, Kohsuke Kondoh, Ryo Nakayama, GOMI Yoshiki, Honoka Tsunematsu, Takahisa Inoue, GOTOH Kohei, Licht Miyamoto, Masafumi Funamoto, Hiromichi Fujino, Yasumasa Ikeda and Koichiro Tsuchiya :
PARP阻害剤は低酸素環境下において生じる5-FU治療効果の減弱を回復させる,
生体機能と創薬シンポジウム2023, Aug. 2023.
32. Natsuki Toyota, Masaki Imanishi, Takahisa Inoue, Honoka Tsunematsu, GOTOH Kohei, Licht Miyamoto, Masafumi Funamoto, Yasumasa Ikeda and Koichiro Tsuchiya :
亜硝酸塩が有するヒドロキシルラジカル消去活性の検討,
生体機能と創薬シンポジウム2023, Aug. 2023.
33. GOMI Yoshiki, Masaki Imanishi, Takahisa Inoue, Keijo Fukushima, Ryosuke Yamashita, Ryo Nakayama, Masataka Nojima, Kohsuke Kondoh, SAWAMURA Takaya, Honoka Tsunematsu, GOTOH Kohei, Licht Miyamoto, Masafumi Funamoto, Hiromichi Fujino, Yasumasa Ikeda and Koichiro Tsuchiya :
TCGAがんゲノムビッグデータとGEOトランスクリプトームデータとの統合解析による膵がん治療標的候補遺伝子の探索,
生体機能と創薬シンポジウム2023, Aug. 2023.
34. Amiho Muramatsu, Masafumi Funamoto, Miyako Ueno, Masaki Imanishi, Yasumasa Ikeda and Koichiro Tsuchiya :
ドキソルビシン心毒性に対する漢方薬効果の検討,
第7回黒潮カンファレンス(宮崎), Jul. 2023.
35. Masafumi Funamoto, Masaki Imanishi, Koichiro Tsuchiya and Yasumasa Ikeda :
病的心肥大と老化におけるマクロファージ鉄ストレスの役割の検討,
,第7回黒潮カンファレンス(宮崎), Jul. 2023.
36. Amiho Muramatsu, Masafumi Funamoto, 上野 実弥子, Masaki Imanishi, Yasumasa Ikeda and Koichiro Tsuchiya :
黄連解毒湯を用いたcGAS/STING/IRF3経路を介したドキソルビシン誘導性心毒性に対する検討,
第8回日本心血管協会(JCVA)学術集会(大分) 2023年6月10日, Jun. 2023.
37. Masafumi Funamoto, Shunji Hirose, Amiho Muramatsu, Masaki Imanishi, Koichiro Tsuchiya and Yasumasa Ikeda :
糖尿病性心筋症におけるエピジェネティックな老化制御機構の解明,
第8回日本心血管協会(JCVA)学術集会(大分), Jun. 2023.
38. Kohsuke Kondoh, Masaki Imanishi, Ryosuke Yamashita, Keijo Fukushima, Ryo Nakayama, Honoka Tsunematsu, Takahisa Inoue, GOTOH Kohei, Licht Miyamoto, Masafumi Funamoto, Hiromichi Fujino, Yasumasa Ikeda and Koichiro Tsuchiya :
5-FUの膵がん細胞増殖抑制効果に対する低酸素―PARP活性化シグナルの役割,
第262回徳島医学会学術集会(徳島), Feb. 2023.
39. Masafumi Funamoto :
COVID-19と心疾患,
第266回徳島医学会学術集会, Feb. 2023.
40. Shunji Hirose, Masafumi Funamoto, Masaki Imanishi, Koichiro Tsuchiya and Yasumasa Ikeda :
2型糖尿病による心筋症モデルマウスの検討,
第262回徳島医学会学術集会, Feb. 2023.
41. SETO Yasuyuki, Masafumi Funamoto and Yasumasa Ikeda :
黄連解毒湯を用いたドキソルビシン誘導性心毒性に対する検討,
第262回徳島医学会学術集会, Feb. 2023.
42. Tatsuki Itoh, Masafumi Funamoto and Yasumasa Ikeda :
急性腎障害に対するマクロファージ鉄ストレスの役割の検討,
第262回徳島医学会学術集会, Feb. 2023.
43. SUENAGA Aoi, Masafumi Funamoto and Yasumasa Ikeda :
慢性腎臓病に対する五苓散の効果,
第262回徳島医学会学術集会, Feb. 2023.
44. Masaki Imanishi, 山下 竜介, Keijo Fukushima, 近藤 宏祐, 中山 涼, 常松 保乃加, 井上 貴久, 後藤 廣平, Masafumi Funamoto, Hiromichi Fujino, Yasumasa Ikeda and Koichiro Tsuchiya :
5-FU膵がん細胞増殖抑制効果に対する低酸素-PARPシグナルの役割,
第52回心脈管作動物質学会, Feb. 2023.
45. Masafumi Funamoto, 砂川 陽一, 刀坂 泰史, 清水 果奈, 長谷川 浩二 and 森本 達也 :
心不全の進展においてBRG1/p300複合体はH3K122のアセチル化を増加した,
第96回日本薬理学会年会, Nov. 2022.
46. Yasumasa Ikeda, Masafumi Funamoto and Hiroyoshi Sei :
New Attempt of Practice in Pharmacology Joint Practice with Basic Medical Departments in Tokushima University-,
第96回日本薬理学会年会 教育企画シンボジウム, Nov. 2022.
47. 山下 竜介, Masaki Imanishi, Keijo Fukushima, 近藤 宏祐, 中山 涼, 常松 保乃加, 井上 貴久, 後藤 廣平, Masafumi Funamoto, Hiromichi Fujino, Yasumasa Ikeda and Koichiro Tsuchiya :
低酸素がん微小環境におけるPARP活性化は5-FUによる膵がん細胞増殖抑制効果の減弱に寄与する,
第142回日本薬理学会近畿部会, Nov. 2022.
48. Masafumi Funamoto, 砂川 陽一, 刀坂 泰史, 清水 果奈, 清水 聡志, 長谷川 浩二, Yasumasa Ikeda and 森本 達也 :
心不全発症時におけるBRG1を介したヒストンのアセチル修飾部位の検討,
第51回日本心脈管作動物質学会, Jul. 2022.
49. Yasumasa Ikeda and Masafumi Funamoto :
漢方薬の腎保作用の検討,
第51回日本心脈管作動物質学会, Jul. 2022.
50. Masafumi Funamoto, Masaki Imanishi, Koichiro Tsuchiya and Yasumasa Ikeda :
ドキソルビシン誘導性心毒性に対するオウゴン成分オウゴニンの効果検討,
第141回日本薬理学会近畿部会, Jul. 2022.
51. Tatsuki Itoh, Masafumi Funamoto, Masaki Imanishi, Koichiro Tsuchiya and Yasumasa Ikeda :
急性腎障害におけるマクロファージ鉄ストレスの役割の検討,
第141回日本薬理学会近畿部会, Jul. 2022.
52. Masafumi Funamoto, Yoichi Sunagawa, Yasufumi Katanasaka, Kana Shimizu, Satoshi Shimizu, Koji Hasegawa, Yasumasa Ikeda and Tatsuya Morimoto :
The Interaction of the p300 with the BRG1 Increases the Acetylation levels of the H3K122 in Heart Failure,
第95回日本薬理学会年会, Mar. 2022.
53. Yasumasa Ikeda, Masafumi Funamoto, Masaki Imanishi and Koichiro Tsuchiya :
漢方薬の新規腎保護作用の検討,
第95回日本薬理学会年会, Mar. 2022.
54. Masafumi Funamoto, 砂川 陽一, 刀坂 泰史, 清水 果奈, 清水 聡志, 長谷川 浩二, Yasumasa Ikeda and 森本 達也 :
心不全期にp300/BRG1複合体がH3K122のアセチル化レベルを増加させた,
第95回日本薬理学会年会, Mar. 2022.
55. Masafumi Funamoto and Yasumasa Ikeda :
生薬由来化合物のオウゴニンによるドキソルビシンの心毒性に対する効果検討,
第31回日本循環薬理学会, Dec. 2021.
56. Masafumi Funamoto and Yasumasa Ikeda :
ドキソルビシンの心毒性に対する生薬由来化合物オウゴニンの効果検討,
第140回日本薬理学会近畿部会, Nov. 2021.
57. Masafumi Funamoto, 砂川 陽一, 刀坂 泰史, 清水 果奈, 宮崎 雄輔, 清水 聡史, 長谷川 浩二, Yasumasa Ikeda and 森本 達也 :
心肥大期から心不全期におけるヒストンのアセチル化修飾部位の検討,
第5回黒潮カンファレンス, Sep. 2021.
58. Masafumi Funamoto, 砂川 陽一, 刀坂 泰史, 清水 果奈, 宮崎 雄輔, 清水 聡史, 長谷川 浩二, Yasumasa Ikeda and 森本 達也 :
心不全発症時におけるヒストンのアセチル化修飾部位の検討,
第263回徳島医学会学術集会, Aug. 2021.
59. Masafumi Funamoto, 砂川 陽一, 刀坂 泰史, 清水 果奈, 宮崎 雄輔, 清水 聡史, 長谷川 浩二, Yasumasa Ikeda and 森本 達也 :
心不全発症におけるヒストンのアセチル化修飾部位の変化を介した転写制御機構の解明,
第28回市大フォーラム, Aug. 2021.

Et cetera, Workshop:

1. Masafumi Funamoto :
糖尿病性心筋症における漢方薬の可能性,
第29回徳島kampo研究会, Feb. 2024.

Grants-in-Aid for Scientific Research (KAKEN Grants Database @ NII.ac.jp)

  • 心不全関連遺伝子領域におけるエピジェネティックな転写制御機構の解明 (Project/Area Number: 22K16106 )
  • Elucidation of transcriptional regulatory mechanisms Involved in the development of heart failure with epigenetic changes (Project/Area Number: 20K22714 )
  • Analysis of epigenetic transcriptional regulatory mechanism in heart failure (Project/Area Number: 17J11509 )
  • Search by Researcher Number (40882064)