Tokushima University / Educator and Researcher Directory --- Koike, Kazuyuki

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Tokushima University ⟩ Graduate School of Biomedical Sciences ⟩ 歯学域 ⟩ Oral Science ⟩ Clinical Dentistry ⟩ Department of Stomatognathic Function and Occlusal Reconstruction ⟩
Tokushima University ⟩ Faculty of Dentistry ⟩ Course in Dentistry ⟩ Clinical Dentistry for Oral Health and Function ⟩ Fixed Prosthodontics ⟩
Tokushima University ⟩ University Hospital ⟩ Clinical Division ⟩ Department of General Dentistry ⟩ Fixed Prosthodontics ⟩

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Research

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https://orcid.org/0000-0002-3660-9438 (ORCID)

Field of Study

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Book / Paper

Academic Paper (Judged Full Paper):

1.	Toyoko Tajima, Maki Hosoki, Mayu Miyagi, Miho Inoue, Aya Ozawa, Mizuki Shinkai, Mio Naritani, Yoshiaki Kubo, Raman Lakshmi Swarna, Parimal Chavan, Kazuyuki Koike and Yoshizo Matsuka : Correlation between pierced earrings and metal allergy prevalence in Tokushima University hospital: A 15-year retrospective analysis, Scientific Reports, Vol.15, No.1, 10939, 2025. (Summary) In Japan, metal allergies are becoming increasingly prevalent, raising concerns for public health. This study examined metal allergy characteristics, patient histories, and clinical signs associated with patch test results over a 15-year period at the Dental Metal Allergy Clinic of Tokushima University Hospital. A retrospective analysis of 1085 patients revealed that 65.4% tested positive for at least one metal allergen, with palladium chloride, nickel sulfate, potassium dichromate, and cobalt chloride identified as the most common allergens. Female patients were disproportionately affected, accounting for 78.4% of the study population. Notably, there was a substantial increase in patients reporting inflammation due to pierced earrings, increasing from 5.0% in 2005 to 43.2% in 2020, particularly among females. Patients with a history of inflammation from earrings had an 81.3% prevalence of metal allergies, which was significantly higher than the 60.4% reported in those without such a history (chi-square test, p < 0.001). These findings suggest a strong link between earrings and metal allergies, underscoring the need for improved education, early detection, and preventive strategies to address the growing impact of metal allergies on public health. (Keyword) Humans / Female / Male / Retrospective Studies / Japan / Adult / Prevalence / Middle Aged / Hospitals, University / Nickel / Allergens / Adolescent / Hypersensitivity / Young Adult / Metals / Aged / Cobalt / Jewelry / Potassium Dichromate / Child / Patch Tests / Dermatitis, Allergic Contact / Palladium (Tokushima University Institutional Repository) ● Metadata: 2013180 (Link to Publication Site) ● Publication site (DOI): 10.1038/s41598-025-86868-1 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 40157960 ● Search Scopus @ Elsevier (PMID): 40157960 ● Search Scopus @ Elsevier (DOI): 10.1038/s41598-025-86868-1 (Tokushima University Institutional Repository: 2013180, DOI: 10.1038/s41598-025-86868-1, PubMed: 40157960)

Proceeding of Domestic Conference:

1.	Daisuke Takegawa, Yoshitaka Suzuki, Kouhei Kamoi, Kazuyuki Koike, Kazuo Okura, Aya Ozawa, 柴垣あかり, Keiichi Hosaka and Yoshizo Matsuka : 3Dプリンターを用いて製作した木管奏者用ミュージックスプリントの形状別主観評価, 日本演奏芸術医学会学術集会, Jul. 2025.
2.	笠井玲緒, Yoshitaka Suzuki, 奥野健太郎, Kazuo Okura, Kazuyuki Koike, Miho Inoue, 新開瑞希, 柴垣あかり, 谷脇竜弥, 渡邊亮友, 高橋一也 and Yoshizo Matsuka : 徳島大学・大阪歯科大学歯学科生における睡眠歯科に対する関心の調査, The Journal of the Japan Prosthodontic Society, May 2025.
3.	Kazuyuki Koike : 「掌蹠膿疱症歯科診療の手引き」WG報告金属アレルギーと掌蹠膿疱症, 第79回NPO法人日本口腔科学会学術集会, May 2025.
4.	Maki Hosoki, Kazuyuki Koike, Toyoko Tajima, Mayu Miyagi and Yoshizo Matsuka : パッチテスト陽性金属除去が有効だった掌蹠膿疱症性骨関節炎の1症例, The Journal of the Japan Prosthodontic Society, May 2025.
5.	Maki Hosoki, Toyoko Tajima, Mayu Miyagi, Kazuyuki Koike, Yoshiaki Kubo, 答島章公, Mariko Niki, Kenji Hirose and Yoshizo Matsuka : 掌蹠膿疱症性骨関節炎における金属アレルギーの関与と治療効果の検討, 日本皮膚免疫アレルギー学会, Dec. 2024.
6.	Kazuyuki Koike, Maki Hosoki, Toyoko Tajima, Mayu Miyagi, Miho Inoue, Daisuke Ikutame, 吉原靖智, 谷脇竜弥, Masamitsu Ohshima and Yoshizo Matsuka : 掌蹠膿疱症性骨関節炎における歯科金属除去の重要性:症例報告と考察, 日本補綴学会中国四国支部学術大会, Aug. 2024.