Tokushima University / Educator and Researcher Directory --- Takeda, Asuka

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Tokushima University ⟩ University Hospital ⟩ Central Clinical Facilities ⟩ Maternity and Perinatal Care Unit ⟩
Tokushima University ⟩ University Hospital ⟩ Clinical Division ⟩ Department of Pediatrics,Obstetrics and Gynecology ⟩ Obstetrics snd Gynecology ⟩

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Research

Field of Study

Subject of Study

Book / Paper

Academic Paper (Judged Full Paper):

1.	Ayako Suto, Yuya Yano, Yuri Yamamoto, Hiroki Noguchi, Asuka Takeda, Shota Yamamoto, Tomohiro Kagawa, Kanako Yoshida, Kenji Hinokio, Akira Kuwahara, Toshiyuki Yasui and Takeshi Iwasa : Effects of activation with a Ca ionophore and roscovitine on the development of human oocytes that failed to fertilize after ICSI., The Journal of Medical Investigation : JMI, Vol.70, No.3.4, 321-324, 2023. (Summary) Sequential treatment with an Ca ionophore and roscovitine activates oocytes that remain unfertilized after ICSI. In TESE-ICSI, the activation rate tended to be increased by the co-administration of roscovitine with a Ca ionophore. J. Med. Invest. 70 : 321-324, August, 2023. (Keyword) Humans / male / Ionophores / Sperm Injections, Intracytoplasmic / Roscovitine / Semen / Oocytes (Link to Publication Site) ● Publication site (DOI): 10.2152/jmi.70.321 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 37940514 ● Search Scopus @ Elsevier (PMID): 37940514 ● Search Scopus @ Elsevier (DOI): 10.2152/jmi.70.321 (DOI: 10.2152/jmi.70.321, PubMed: 37940514)

Academic Paper (Unrefereed Paper):

1.	Takeshi Iwasa, Hiroki Noguchi, Risa Tanano, Erika Yamanaka, Asuka Takeda, Kou Tamura, Hidenori Aoki, Tatsuro Sugimoto, Hikari Sasada, Takaaki Maeda, Saki Minato, Shota Yamamoto, Hiroaki Inui, Tomohiro Kagawa, Atsuko Yoshida, Ayuka Mineda, Mari Nii, Riyo Kinouchi, Kanako Yoshida, Yuri Yamamoto and Takashi Kaji : Age-Dependent Changes in the Effects of Androgens on Female Metabolic and Body Weight Regulation Systems in Humans and Laboratory Animals., International Journal of Molecular Sciences, Vol.24, No.23, 16567, 2023. (Summary) In recent years, the effects of androgens on metabolic and body weight regulation systems and their underlying mechanisms have been gradually revealed in females. In women and experimental animals of reproductive age, androgen excess can adversely affect metabolic functioning, appetite, and body weight regulation. In addition, excess androgens can increase the risk of metabolic disorders, such as obesity, insulin resistance, and diabetes. These unfavorable effects of androgens are induced by alterations in the actions of hypothalamic appetite-regulatory factors, reductions in energy expenditure, insulin resistance in skeletal muscle, and β-cell dysfunction. Interestingly, these unfavorable effects of androgens on metabolic and body-weight regulation systems are neither observed nor evident in ovariectomized animals and post-menopausal women, indicating that the adverse effects of androgens might be dependent on the estrogen milieu. Recent findings may provide novel sex- and age-specific strategies for treating metabolic diseases. (Keyword) Animals / Humans / female / Androgens / Insulin Resistance / Obesity / Metabolic Diseases / Animals, Laboratory / Polycystic Ovary Syndrome (Link to Publication Site) ● Publication site (DOI): 10.3390/ijms242316567 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 38068890 ● Search Scopus @ Elsevier (PMID): 38068890 ● Search Scopus @ Elsevier (DOI): 10.3390/ijms242316567 (DOI: 10.3390/ijms242316567, PubMed: 38068890)