Tokushima University / Educator and Researcher Directory --- Mizuguchi, Makoto

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Tokushima University ⟩ University Hospital ⟩ Clinical Division ⟩ Department of Ophthalmology, Otolaryngology, Dermatology, Orthopedics, and Plastic Surgery ⟩ Plastic · Aesthetic Surgery ⟩

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Research

Field of Study

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Book / Paper

Academic Paper (Judged Full Paper):

1.	Kazuhide Mineda, Katsuya SATO, Tasuku Nakahara, Kazuyuki Minami, Kenta Ikushima, Makoto Mizuguchi, Shunsuke Mima, Hiroyuki Yamasaki, Shinji Nagasaka, Yutaro Yamashita, Yoshiro Abe and Ichiro Hashimoto : Specific Calcium Signal Responses in Human Keloid-Derived Fibroblasts During Cyclical Stretching: Basic Research, Health Science Reports, 8, 3, e70461, 2025. (Keyword) calcium oscillation / calcium signal response / calcium spike / cyclical stretching / intracellular Ca2+ / keloid (Link to Publication Site) ● Publication site (DOI): 10.1002/hsr2.70461 (Link to Search Site for Scientific Articles) ● Summary page in Scopus @ Elsevier: 2-s2.0-86000123839 (DOI: 10.1002/hsr2.70461, Elsevier: Scopus)
2.	Yutaro Sasaki, Yasuyo Yamamoto, Makoto Mizuguchi, Saki Kobayashi, Shinji Nagasaka, Takuya Tokunaga and Junya Furukawa : A case of laparoscopically assisted vulvar reconstruction using the gluteal fold flap for anterior enterocele after robot-assisted radical cystectomy in a woman., IJU Case Reports, 8, 2, 121-124, 2025. (Summary) Vaginal complications following radical cystectomy may require surgical treatment. We herein report a case of successful laparoscopically assisted vulvar reconstruction using the gluteal fold flap for anterior enterocele following robot-assisted radical cystectomy. A 71-year-old Japanese woman underwent robot-assisted radical cystectomy for bladder cancer (ypT1ypN1M0). The bladder, urethra, bilateral ovaries, and anterior vaginal wall were removed together transvaginally. The Mercedes-Benz closure technique was performed for vaginal reconstruction using the posterior vaginal wall. Seventeen months after surgery, she complained of a vulvar bulge, and physical examination confirmed a tennis ball-sized anterior enterocele. Therefore, she underwent laparoscopically assisted vulvar reconstruction using the gluteal fold flap. No recurrence had developed at 6 months postoperatively. The combination with laparoscopy allows vulvar reconstruction to be performed safely and efficiently. (Link to Publication Site) ● Publication site (DOI): 10.1002/iju5.12823 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 40034917 ● Summary page in Scopus @ Elsevier: 2-s2.0-85214420561 (DOI: 10.1002/iju5.12823, PubMed: 40034917, Elsevier: Scopus)

Proceeding of Domestic Conference:

1.	西岡真理子, Yutaro Yamashita, Makoto Mizuguchi, Kazuhide Mineda, Yoshiro Abe and Ichiro Hashimoto : 褥瘡手術においてSSIによる創離開を予防する工夫, 第26回日本褥瘡学会中国四国地方会学術集会, Mar. 2026.
2.	Yoshiro Abe, Kazuhide Mineda, Yutaro Yamashita, Mai Nakagawa, Makoto Mizuguchi and Ichiro Hashimoto : ビデオシンポジウム④『皮膚悪性腫瘍』下眼瞼の整容性と機能性を高める skin-tarsoligamentous sling 再建, 第31回日本形成外科手術手技学会, Mar. 2026.
3.	Yutaro Yamashita, 西岡真理子, Yoshiro Abe, Makoto Mizuguchi, Mai Nakagawa, Kazuhide Mineda and Ichiro Hashimoto : 軟部組織感染症によるアキレス腱部分断裂に対して腓腹筋腱膜付sural flapにて再建を行った1例, 第6回日本フットケア・足病医学会年次学術集会, Feb. 2026.
4.	井上拓人, Yutaro Yamashita, 戸田皓大, Makoto Mizuguchi, Mai Nakagawa, Kazuhide Mineda, Yoshiro Abe and Ichiro Hashimoto : 足底の慢性異物による立法骨骨髄炎に対してCRAP療法を行った例, 第88回中四国形成外科学会学術集会, Feb. 2026.
5.	Yutaro Yamashita, Yoshiro Abe, Kazuhide Mineda, Shinji Nagasaka, Mai Nakagawa, Makoto Mizuguchi and Ichiro Hashimoto : Implementation and outcome of surgical offloading, Int J Surg Wound Care., 7, 1, 1-5, Feb. 2026.
6.	Yoshiro Abe, Makoto Mizuguchi, Kazuhide Mineda, Yutaro Yamashita, Mai Nakagawa and Ichiro Hashimoto : 植皮を要した腓骨皮弁採取部の合併症に関する検討, 第52回日本マイクロサージャリー学会学術集会, Oct. 2025.
7.	生島健太, Kazuhide Mineda, Yoshiro Abe, Yutaro Yamashita, Mai Nakagawa, Makoto Mizuguchi and Ichiro Hashimoto : シンポジウムC『組織工学による階層的血管網を有する吻合可能な人工血管を用いた血管柄付き脂肪組織の開発』, 第34回日本形成外科学会基礎学術集会, Oct. 2025.
8.	Yutaro Yamashita, Yoshiro Abe, Shinji Nagasaka, 伊澤勝哉, Makoto Mizuguchi, Mai Nakagawa, IKUSHIMA Kenta and Ichiro Hashimoto : ヒト羊膜製品EPIFIX®の使用方法と適応症例についての検討., 日本形成外科学会会誌, 45, 10, 467-475, Oct. 2025.
9.	Yutaro Yamashita, Yoshiro Abe, Kazuhide Mineda, Mai Nakagawa, Makoto Mizuguchi and Ichiro Hashimoto : 当科で実施したoff-loading surgeryの検討, 第7回日本フットケア・足病医学会中国四国地方会学術集会, Sep. 2025.
10.	生島健太, Yoshiro Abe, Kazuhide Mineda, Yutaro Yamashita, Shinji Nagasaka, Mai Nakagawa, Makoto Mizuguchi and Ichiro Hashimoto : Reconstruction for Extensive Abdominal Wall Defects Using Free Anterolateral Thigh Flap with Vascularized Fascia Lata: Three case reports, The 16th Korea-Japan Congress of Plastic and Reconstructive Surgery, Sep. 2025.
11.	Yoshiro Abe, Kazuhide Mineda, Yutaro Yamashita, Makoto Mizuguchi, IKUSHIMA Kenta and Ichiro Hashimoto : Functional outcomes of reconstructive flap surgery for soft tissue sarcoma: Long-term outcomes of functional restoration using innervated muscle transplantation in our facility, The 16th Korea-Japan Congress of Plastic and Reconstructive Surgery, Sep. 2025.
12.	NISHIOKA Mariko, Ichiro Hashimoto, Yoshiro Abe, Kazuhide Mineda, Yutaro Yamashita, Mai Nakagawa, Makoto Mizuguchi, IKUSHIMA Kenta, 宇都宮佐和子 and 伊澤勝哉 : 両下肢の熱傷に対して持続灌流併用局所陰圧閉鎖療法(NPWTi-d)を行った一例, 第87回中国・四国形成外科学会学術集会, Sep. 2025.
13.	Makoto Mizuguchi, Yoshiro Abe, MIMA Shunsuke, Shinji Nagasaka, Yutaro Yamashita, Kazuhide Mineda and Ichiro Hashimoto : ネキソブリッド®外用ゲルの治療経験∼広範囲熱傷症例における適応と治療戦略∼, 第51回日本熱傷学会総会・学術集会, May 2025.
14.	MIMA Shunsuke, Yoshiro Abe, Kazuhide Mineda, Yutaro Yamashita, Shinji Nagasaka, Mai Nakagawa, Makoto Mizuguchi, IKUSHIMA Kenta and Ichiro Hashimoto : アワードセッション 5Gライブストリーミング遠隔診療で行った手技, 第30回日本形成外手術手技学会, Mar. 2025.
15.	Kazuhide Mineda, Katsuya SATO, Nakahara Tasuku, Minami Kazuyuki, IKUSHIMA Kenta, Makoto Mizuguchi, MIMA Shunsuke, Hiroyuki Yamasaki, Shinji Nagasaka, Yutaro Yamashita, Yoshiro Abe and Ichiro Hashimoto : Specific Calcium Signal Responses in Human Keloid-Derived Fibroblasts During Cyclical Stretching: Basic Research, Health Science Reports, 8, 3, e70461, Mar. 2025. (Link to Publication Site) ● Publication site (DOI): 10.1002/hsr2.70461 (Link to Search Site for Scientific Articles) ● Summary page in Scopus @ Elsevier: 2-s2.0-86000123839 (DOI: 10.1002/hsr2.70461, Elsevier: Scopus)
16.	NISHIOKA Mariko, Ichiro Hashimoto, Yoshiro Abe, Kazuhide Mineda, Yutaro Yamashita, Shinji Nagasaka, 美馬俊介, Mai Nakagawa, Makoto Mizuguchi, IKUSHIMA Kenta, Mai Nakagawa, 宇都宮佐和子, 伊澤勝哉, 中村由実子 and 村上真吾 : 出血性ショックに至る頭部巨大皮下血腫を生じた筋拘縮(古庄)型Ehlers-Danlos症候群の一例, 第86回中国・四国形成外科学会学術集会, Feb. 2025.
17.	伊澤勝哉, MIMA Shunsuke, 岩本晃一, Yoshiro Abe, Kazuhide Mineda, Yutaro Yamashita, Shinji Nagasaka, Makoto Mizuguchi, IKUSHIMA Kenta and Ichiro Hashimoto : ベッドサイドで体幹背面へのThiersch植皮が有効であった広範囲熱傷の1例, 第32回日本熱傷学会中国四国学術集会, Dec. 2024.
18.	Shunsuke Mima, Yoshiro Abe, Kazuhide Mineda, Yutaro Yamashita, Shinji Nagasaka, Hiroyuki Yamasaki, Mayu Bando, Makoto Mizuguchi, Kenta Ikushima, Teruyoshi Kageji and Ichiro Hashimoto : Current Status and Potential of Online Telemedicine in Plastic Surgery, Journal of Plastic and Reconstructive Surgery, 4, 3, 121-126, Dec. 2024. (Summary) <p>Objectives: Remote medical care is becoming popular worldwide, but not as much has yet been done in plastic surgery. We provided online treatment related to plastic surgery using a 5G system. This study aimed to investigate the usefulness and future of online telemedicine in plastic surgery.</p><p>Methods: A plastic surgeon alternated between face-to-face and telemedicine. The interval between consultations was 1 week. Specifically, local doctors and staff provided medical care to patients at the suburban hospital, and the plastic surgeon remotely observed patients and provided instructions and guidance on procedures to the local doctors and staff. In this study, we evaluated the patients who were treated under telemedicine with respect to their age, use, and effectiveness. The study encompassed the period from August 2021 to October 2022.</p><p>Results: Thirty-five patients were treated via online telemedicine (mean age, 73.0 years). Twenty-one (60%) of the postoperative procedures were related to surgeries performed by a plastic surgeon. Consultation for simple wound care was performed in 8 (22.9%) patients. Guidance on pocket incision surgery for pressure ulcers was given to one patient. As for the quality of communication, images were clear, no delays were encountered, and no cases interfered with medical care.</p><p>Conclusions: Our system was primarily useful as a postoperative management tool. The high image quality and low-latency communication allowed for real-time instruction during complex postoperative procedures and surgical techniques. Even in hospitals with infrequent visits from plastic surgeon, telemedicine has the potential to make surgery safer and more proactive.</p> (Keyword) telemedicine / 5G network (Link to Publication Site) ● Publication site (DOI): 10.53045/jprs.2024-0033 (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1390023549706235648 ● Search Scopus @ Elsevier (DOI): 10.53045/jprs.2024-0033 (DOI: 10.53045/jprs.2024-0033, CiNii: 1390023549706235648)
19.	青雅一, Hiromichi Sedo, Yoshiro Abe, Makoto Mizuguchi, 植村亨裕, 佐藤孝蔵, 駒越翔, 上村由美子, 手塚敬 and 村上達郎 : 第12回中国・四国形成外科施設間研究報告会「外鼻腫瘍切除時の再建方法と術後変形に関する実態調査」, 第84回中国・四国形成外科学会学術集会, Feb. 2024.