Tokushima University / Educator and Researcher Directory --- Ninomiya, Masami

Personal Web Page

https://researchmap.jp/read0188858 (researchmap)

Field of Study

○	Periodontology
○	Periodontology
○	Endodontology

Subject of Study

○	MMP inhibitorの歯周病治療薬への応用 (MMP inhibitor, periodontal regeneration)
○	自家歯牙移植への歯周組織再生誘導材料の応用 (autotransplantation, periodontal regeneration)
○	歯髄組織中の基質蛋白と石灰化との関係に関する研究 (dental pulp, calcification, osteopontin)

Book / Paper

Book:

1.	Masami Ninomiya and Hiromichi Yumoto : 進行した歯周病を治す最新の歯周再生療法, Mar. 2024.
2.	Masami Ninomiya : 糖尿病患者では歯周病の増悪がみられるか．, The Japanese Society of Periodontology, Jun. 2023. (Keyword) diabetes mellitus / periodontitis
3.	Masami Ninomiya and Hiromichi Yumoto : 歯周病の病因, 株式会社永末書店, Jan. 2021.
4.	高柴正悟, 池田淳史, Hiromichi Yumoto, Masami Ninomiya and Takahisa Ikuta : WORKGROUP 2: PERIODONTITIS, 急性歯周疾患(歯周膿瘍と壊死性歯周疾患)と歯内―歯周病変, Oct. 2020.
5.	Hiromichi Yumoto, Katsuhiko Hirota, Kouji Hirao, Masami Ninomiya, Keiji Murakami, Hideki Fujii and Yoichiro Miyake : The Pathogenic Factors from Oral Streptococci for Systemic Diseases, Aug. 2020.
6.	Masami Ninomiya : FGF2と歯周組織再生療法リグロスの効果，手術のポイント，応用例, クインテンセンス出版株式会社, Tokyo, Aug. 2020. (Keyword) Fibroblast growth factorF-2 / Periodontal regeneration therapy / Regroth
7.	Masami Ninomiya and Hiromichi Yumoto : 特殊な歯周病の治療, 医歯薬出版株式会社, Feb. 2020.
8.	Masami Ninomiya and Hiromichi Yumoto : クイズで学ぶ口腔疾患123, Dental Diamond Co., Tokyo, Mar. 2019. (Keyword) drug-induced gingival overgrowth / necrotizing ulcerative periodontitis / aggressive periodontitis / vertical root flacture
9.	Masami Ninomiya and Toshihiko Nagata : 臨床編歯周病の病因, 永末書店, Jan. 2016. (Keyword) periodontitis
10.	Masami Ninomiya : 糖尿病で薬物性歯肉増殖症を合併している歯周病患者へどのように対応したらよいですか．, 医歯薬出版株式会社, Jan. 2016. (Keyword) periodontitis / 薬物性歯肉増殖症 / diabetes mellitus
11.	Masami Ninomiya and Toshihiko Nagata : 高齢者透析患者の口腔内病変はどのように発見し対策を立てますか?, 医歯薬出版株式会社, Sep. 2014. (Keyword) dialysis / 高齢者 / 歯周病
12.	Toshihiko Nagata and Masami Ninomiya : 口腔ケア実践上のノウハウ糖尿病になるとう蝕や歯周病になりやすい? 糖尿病患者の口腔ケアで注意点，強調すべき点は?, 医歯薬出版株式会社, Tokyo, Mar. 2013. (Keyword) diabetes mellitus / periodontitis / 口腔ケア
13.	Masami Ninomiya and Toshihiko Nagata : 歯周病治療の基礎と臨床臨床編 1章歯周病の病因, Mar. 2011.
14.	Toshihiko Nagata and Masami Ninomiya : 歯科衛生士教本·歯周病の治療, 永末書店, Kyoto, Dec. 2005.

Academic Paper (Judged Full Paper):

1.	Masami Ninomiya, Mari Hashimoto, Kouji Yamanouchi, Yoshiaki Fukumura, Toshihiko Nagata and Koji Naruishi : Relationship of oral conditions to the incidence of infective endocarditis in periodontitis patients with valvular heart disease: a cross-sectional study., Clinical Oral Investigations, Vol.24, No.2, 833-840, 2020. (Summary) The patients with IE had fewer remaining teeth, more advanced bone resorption compared with those of patients without IE. These findings suggest a possible association between the occurrence of IE and periodontal infection. (Keyword) Infective endocarditis / Valvular heart disease / periodontitis (Tokushima University Institutional Repository) ● Metadata: 113773 (Link to Publication Site) ● Publication site (DOI): 10.1007/s00784-019-02973-2 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 31197658 ● Summary page in Scopus @ Elsevier: 2-s2.0-85067639107 (Tokushima University Institutional Repository: 113773, DOI: 10.1007/s00784-019-02973-2, PubMed: 31197658, Elsevier: Scopus)
2.	Hiromichi Yumoto, Katsuhiko Hirota, Kouji Hirao, Masami Ninomiya, Keiji Murakami, Hideki Fujii and Yoichiro Miyake : The pathogenic factors from oral Streptococci for systemic diseases, International Journal of Molecular Sciences, Vol.20, No.18, 2019. (Tokushima University Institutional Repository) ● Metadata: 114574 (Link to Publication Site) ● Publication site (DOI): 10.3390/ijms20184571 (Link to Search Site for Scientific Articles) ● Summary page in Scopus @ Elsevier: 2-s2.0-85072542634 (Tokushima University Institutional Repository: 114574, DOI: 10.3390/ijms20184571, Elsevier: Scopus)
3.	Keiko Aota, Kohichi Kani, Tomoko Yamanoi, Yukihiro Momota, Masami Ninomiya, Hiromichi Yumoto and Masayuki Azuma : Management of tooth extraction in a patient with ELANE gene mutation-induced cyclic neutropenia: A case report., Medicine, Vol.98, No.39, e17372, 2019. (Summary) Cyclic neutropenia (CyN) is a rare hematological disease, and patients with CyN often experience an early onset of severe periodontitis and are forced to undergo tooth extraction. Here, we report a case of a patient with CyN who showed different periodicity and oscillations of neutrophil count compared with her mother, despite sharing the same novel genetic mutation. A 17-year-old Japanese girl who had been diagnosed with CyN shortly after birth presented to our hospital with a complaint of mobility of her teeth and gingivitis. Upon presentation, an intraoral examination was performed and revealed redness and swelling of the marginal and attached gingiva. Radiographs revealed extreme resorption of the alveolar bone and apical lesions in her mandibular lateral incisors. The patient's hematologic data demonstrated a lack of blood neutrophils (0/μL). The patient had no history of dental extraction, and her mother also had a history of CyN. The patient was diagnosed with severe periodontitis that was associated with CyN. Gene testing showed a novel heterozygous mutation in exon 4 of the ELANE gene (c.538delC, p.Leu180Ser fsX11). Based on the clinical findings, we planned to extract the patient's mandibular lateral incisors. Although the tooth extraction was scheduled considering the cyclic variation in neutrophil count, the patient's neutrophil count was 0/μL on the day before the planned extraction. Therefore, granulocyte-colony stimulating factor (G-CSF) was administered to increase the patient's neutrophil count. On the day of the patient's admission for the tooth extraction, she presented with fever (body temperature, 38.5°C), tonsillitis, and stomatitis. The extraction was subsequently delayed, and the patient was administered antibiotics and G-CSF for 4 days. At this time, the neutrophil count increased to 750/μL, and the tooth extraction was carried out safely. The postoperative course was uneventful, and the healing process at the extraction site was excellent. There is a possibility that the periodicity and oscillations of neutrophil count may change with growth in patients with CyN. Therefore, it is important to frequently examine and treat patients with fluctuating neutrophil levels for the management of invasive dental treatment in patients with CyN. (Keyword) Adolescent / Exons / female / Humans / Leukocyte Count / Leukocyte Elastase / Mutation / Neutropenia / Neutrophils / periodontitis / Tooth Extraction (Tokushima University Institutional Repository) ● Metadata: 115183 (Link to Publication Site) ● Publication site (DOI): 10.1097/MD.0000000000017372 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 31574885 ● Summary page in Scopus @ Elsevier: 2-s2.0-85072847226 (Tokushima University Institutional Repository: 115183, DOI: 10.1097/MD.0000000000017372, PubMed: 31574885, Elsevier: Scopus)
4.	Masami Ninomiya : Report of comprehensive periodontal treatment of a case of severe drug-induced gingival overgrowth with malaligned teeth, Journal of the Japanese Association of Periodontology, Vol.61, No.1, 37-46, 2019. (Keyword) Drug-induced gingival overgrowth / Ca cannnel blocker / Comprehensive periodontal treatment (Tokushima University Institutional Repository) ● Metadata: 113210 (Link to Publication Site) ● Publication site (DOI): 10.2329/perio.61.37 (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1390845713070217984 ● Search Scopus @ Elsevier (DOI): 10.2329/perio.61.37 (Tokushima University Institutional Repository: 113210, DOI: 10.2329/perio.61.37, CiNii: 1390845713070217984)
5.	Chie Wada -Mihara, Koji Naruishi, Mika Bandou, Yasufumi Nishikawa, Lew Jung-Hwan, Eijiro Sakamoto, Takahisa Ikuta, Kaoru Kono, Yukari Kajiura, Mari Hashimoto, Yukiko Nakajima, Yuji Inagaki, Masami Ninomiya, Jun-ichi Kido and Toshihiko Nagata : Post clinical clerkship-OSCEを見据えた歯周病科での模擬OSCEの概要, Journal of Oral Health and Biosciences, Vol.29, No.2, 49-53, 2017. (Tokushima University Institutional Repository) ● Metadata: 111059 (Link to Publication Site) ● Publication site (DOI): 10.20738/johb.29.2_49 (Link to Search Site for Scientific Articles) ● Search Scopus @ Elsevier (DOI): 10.20738/johb.29.2_49 (Tokushima University Institutional Repository: 111059, DOI: 10.20738/johb.29.2_49)
6.	Koji Naruishi, Keiji Oishi, Yuuji Inagaki, Masumi Horibe, Mika Bandou, Masami Ninomiya, K Kawahara, J Minakuchi, S Kawashima, K Shima, Jun-ichi Kido and Toshihiko Nagata : Association between Periodontal Condition and Kidney Dysfunction in Japanese Adults: A Cross-Sectional Study, Clinical and Experimental Dental Research, Vol.2, No.2, 1-8, 2016. (Tokushima University Institutional Repository) ● Metadata: 115061 (Link to Publication Site) ● Publication site (DOI): 10.1002/cre2.39 (Link to Search Site for Scientific Articles) ● Search Scopus @ Elsevier (DOI): 10.1002/cre2.39 (Tokushima University Institutional Repository: 115061, DOI: 10.1002/cre2.39)
7.	Yukihiro Momota, Maki Hosoki, Masami Ninomiya, Hideyuki Takano, Yoshizo Matsuka and Masayuki Azuma : 口腔ならびに呼吸器症状を呈した歯科用金属によるアレルギーの1例, Journal of Japanese Society for Evidence and the Dental Professional, Vol.8, No.1, 39-44, 2016.
8.	Masami Ninomiya, Tomoko Azuma, Jun-ichi Kido, Shinya Murakami and Toshihiko Nagata : Successful case of periodontal tissue repair by fibroblast growth factor-2. -Long-term follow-up and comparison with enamel matrix derivative-, Clinical Advances in Periodontics, Vol.3, No.4, 216-221, 2013. (Link to Publication Site) ● Publication site (DOI): 10.1902/cap.2012.120014 (Link to Search Site for Scientific Articles) ● Search Scopus @ Elsevier (DOI): 10.1902/cap.2012.120014 (DOI: 10.1902/cap.2012.120014)
9.	Masami Ninomiya, Nobuyuki Kamata, Masaru Nagayama and Toshihiko Nagata : エナメル基質タンパクの歯の移植への応用, the Quintessence, Vol.23, No.7, 89-96, 2004.
10.	Masami Ninomiya, Akane Takemura and Toshihiko Nagata : MMP 阻害剤の歯槽骨吸収抑制作用, the Quintessence, Vol.22, No.9, 41-47, 2003. (Keyword) マトリックスメタロプロテアーゼ(MMP) / MMPインヒビター / 歯周病
11.	Masami Ninomiya, Nobuyuki Kamata, Ryoichi Fujimoto, Tomoko Ishimoto, (名) Suryono, Jun-ichi Kido, Masaru Nagayama and Toshihiko Nagata : Application of Enamel Matrix Derivative in Autotransplantation of an Impacted Maxillary Premolar, Journal of Periodontology, Vol.73, No.3, 346-351, 2002. (Summary) The success of tooth transplantation or replantation depends on the viability of periodontal ligament in the planted tooth. Mechanical injury to periodontal tissues frequently results in dental root resorption and dental ankylosis, which leads to the failure of transplantation or replantation. Enamel matrix derivative (EMD) has been recently used to induce periodontal regeneration. In this report, we show a clinical case of EMD application in the transplantation of an inversely impacted and immature tooth. An impacted second premolar was found in the right maxilla of a 16 year-old girl. The tooth was inversely impacted and the dental root was incomplete. When transplantation was carried out, EMD was applied to the periodontal tissues of the extracted premolar. The tooth was fixed at the correct position and the clinical condition was followed for evaluation for 6 months. Radiographs after 3 months exhibited new bone formation surrounding the transplanted tooth. After 6 months, considerable growth of dental root was evident, periodontal ligament-like radiolucency appeared, the vital reaction of the planted tooth was detected, and there were no signs of root resorption or ankylosis. Short-term results from this case indicate that EMD application was effective in the transplantation of an inversely impacted and immature tooth and that EMD might contribute to the growth of dental root and to the prevention of ankylosis. (Keyword) enamel matrix derivative / autotransplantation / periodontal membrane (Link to Publication Site) ● Publication site (DOI): 10.1902/jop.2002.73.3.346 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 11922266 ● Search Scopus @ Elsevier (PMID): 11922266 ● Search Scopus @ Elsevier (DOI): 10.1902/jop.2002.73.3.346 (DOI: 10.1902/jop.2002.73.3.346, PubMed: 11922266)
12.	Nobuyuki Kamata, Masami Ninomiya, Tomoko Azuma, Ryoichi Fujimoto, Mayumi Tomonari, Toshihiko Nagata and Masaru Nagayama : Autotransplantation of Impacted Teeth and Wisdom Teeth, Shikoku Dental Research, Vol.15, No.1, 205-213, 2002. (Keyword) 移植 / 智歯 / 埋伏歯
13.	Masami Ninomiya, Mika Oishi, Jun-ichi Kido, Yasuyoshi Ohsaki and Toshihiko Nagata : Immunohistochemical Localization of Osteopontin in human Pulp Stones., Journal of Endodontics, Vol.27, No.4, 269-272, 2001. (Summary) The organic matrix component of human pulp stones was investigated by immunohistochemistry. Two pulp stones were extracted from the upper molar teeth of two patients suffering from irreversible pulpitis. Both were formed in the center of the pulp cavity and located apart from the dentin walls. After demineralization, serial sections of the stones were prepared and subjected to immunohistochemical procedures using specific antibodies to type I collagen and noncollagenous proteins (osteopontin, osteonectin, and osteocalcin), which are reported to be involved in calcified matrix formation. Type I collagen was localized evenly in the stones, indicating that it is a major matrix component of pulp stones. Strong immunostaining of osteopontin appeared in the peripheral area of the stones, whereas osteonectin and osteocalcin were not detected. We previously reported that dental pulp cells produced osteopontin in vitro. Osteopontin has been commonly found in other pathological calcification, such as urinary stones, atherosclerotic plaques, and dental calculus. Taken together, the present findings suggest that osteopontin produced by dental pulp cells is possibly associated with calcification of the pulp stone matrix. (Keyword) osteopontin / pulp stone / calcification (Link to Publication Site) ● Publication site (DOI): 10.1097/00004770-200104000-00007 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 11485265 ● Summary page in Scopus @ Elsevier: 2-s2.0-0035317644 (DOI: 10.1097/00004770-200104000-00007, PubMed: 11485265, Elsevier: Scopus)
14.	Masatoshi Kataoka, YASUKI SHIMIZU, KENJI KUNIKIYO, YOJI ASAHARA, Kikuji Yamashita, Masami Ninomiya, Ichijiro Morisaki, Yasuyoshi Ohsaki, Jun-ichi Kido and Toshihiko Nagata : Cyclosporin A Decreases the Degradation of Type I Collagen in Rat Gingival Overgrowth, Journal of Cellular Physiology, Vol.182, No.3, 351-358, 2000. (Summary) Cyclosporin A (CsA) is used as an immunosuppressive agent and its prominent side effect is the induction of fibrous gingival overgrowth. The purpose of this study was to investigate the effect of CsA on the type I collagen metabolism in the gingiva of rats fed a powdered diet either containing or lacking CsA. Immunohistochemical analysis revealed that type I collagen was more prevalent in the connective tissue of CsA-treated gingiva than in those of control rats on days 15, 30, and 55 after the start of feeding. Total RNAs were isolated from mandibular molar gingiva on days 0, 3, 8, 15, 30, and 55. Quantitative analysis of mRNA by reverse transcriptase-polymerase chain reaction revealed that the CsA-treated groups showed a gradual decrease in expression of type I collagen and collagenase mRNAs, 0.4% and 18.0% on day 55 compared with those on day 0, respectively. In the control groups, type I collagen and collagenase mRNAs also decreased to 19.7% and 63.0%, respectively, however, both mRNA expressions were significantly lower in the CsA-treated group than in the controls. An electron microscopic analysis of fibroblasts was performed to count the number of cells with collagen fibrils in the cytoplasm, a marker of phagocytosis of collagen by fibroblasts. The collagen fibrils were detected in 4.7% +/- 2.7% and 24.3% +/- 13.7% of fibroblasts in the overgrown gingiva treated with CsA rat for 8 days and 30 days, but in 57.0% +/- 5.3% and 81.3% +/- 9.2% of fibroblasts in the each control group gingiva, respectively. Furthermore, in vitro analysis was performed to measure the phagocytosis of cultured fibroblasts by flow cytometry using collagen-coated latex beads. Fibroblasts isolated from CsA-treated gingiva on day 8 and day 30 contained 5.7% +/- 0.6% and 9.9% +/- 1.5% phagocytic cells, whereas control fibroblasts contained 50.3% +/- 5.5% and 33.3% +/- 4.9% phagocytic cells, respectively. The inhibition rate of phagocytic activity was similar between in vivo and in vitro assays. These findings suggest that the decrease of the collagen degradation due to the lower phagocytosis and the lower collagenase mRNA expression are closely associated with the increase of type I collagen accumulation in CsA-treated rat gingiva. (Keyword) Animals / Cell Division / Cells, Cultured / Collagen / Collagenases / Cyclosporine / Fibroblasts / Gene Expression / Gingiva / Gingival Overgrowth / Immunosuppressive Agents / Latex / male / Microscopy, Electron / Microspheres / Phagocytosis / RNA, Messenger / Rats / Rats, Inbred F344 / Reverse Transcriptase Polymerase Chain Reaction / Specific Pathogen-Free Organisms (Link to Publication Site) ● Publication site (DOI): 10.1002/(SICI)1097-4652(200003)182:3<351::AID-JCP5>3.0.CO;2-U (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 10653601 ● Summary page in Scopus @ Elsevier: 2-s2.0-0033957168 (DOI: 10.1002/(SICI)1097-4652(200003)182:3<351::AID-JCP5>3.0.CO;2-U, PubMed: 10653601, Elsevier: Scopus)
15.	Masami Ninomiya, 大場堂信, 二宮洋介, 中野恵子, Mika Oishi, 浅原洋士, Masatoshi Kataoka, 篠原啓之, Jun-ichi Kido and Toshihiko Nagata : ハムスター実験的歯周炎におけるプロスタグランディンE₂の歯槽骨吸収抑制効果, The Japanese Society of Conservative Dentistry, Vol.43, No.6, 1138-1144, 2000.
16.	Dai Ikedo, Yoji Asahara, Takamasa Sawa, Keiji Oishi, Noriyuki Yamauchi, Yasuki Shimizu, Mika Oishi, Masami Ninomiya, Masatoshi Kataoka, Hiroyuki Shinohara, Jun-ichi Kido and Toshihiko Nagata : Stimulatory Effects of Phenytoin on Osteoblastic Differentiation in Cultured MC3 T3-E1 Cells, Journal of the Japanese Association of Periodontology, Vol.42, No.2, 104-113, 2000. (Keyword) phenytoin / osteoblasts / differentiation / MC3 T3-E1
17.	Masami Ninomiya : Comparative histological study of mineralizations after intramuscular Implantations of heat-denatured demineralized bone matrix gelatin,heat-denatured demineralized tooth, and cross-linked collagen, Shikoku Dental Research, Vol.9, No.1, 77-97, 1996. (Keyword) Demineralized bone matrix gelatin / Dentin / collagen / Bone morphogenetic facter / calcification
18.	Masami Ninomiya, Kikuji Yamashita, Toshihiko Nagata and Seiichiro Kitamura : ラット後肢の指骨切断後の治癒過程に及ぼすethane-1-hydroxy-1, 1-diphosphonateの影響—光学顕微鏡所見を中心に—, Shikoku Dental Research, Vol.8, No.2, 189-206, 1996.
19.	Kikuji Yamashita, Masami Ninomiya, Tomomichi Takagi, Hiroshi Ishizuka and Seiichiro Kitamura : Human alveolar bone cells in vitro, Biomedical Research (India), Vol.6, No.1, 1-9, 1995.
20.	Kikuji Yamashita, Masami Ninomiya, S. A. Sanjabad, M. Kuwahara and Seiichiro Kitamura : Histological study on endochondral ossification in the osteopetrotic op/op mouse, Dentistry in Japan, Vol.32, 3-8, 1995.
21.	Masami Ninomiya, Takanobu Ohba, Yohsuke Ninomiya, Keikko Nakano, Mika Oishi, Yoji Asahara, Masatoshi Kataoka, Hiroyuki Shinohara, Jun-ichi Kido and Toshihiko Nagata : Inhibitory Effects of Prostaglandin E2 on Alveolar Bone Resorption in Hamster Experimental Periodontitis, The Japanese Journal of Conservative Dentistry, Vol.43, No.6, 1138-1144, 1988.

Academic Paper (Unrefereed Paper):

1.	Jun-ichi Kido, Mika Bandou, Yuji Inagaki, 生田貴久, Yukari Kajiura, Yukiko Nakajima, Eijiro Sakamoto, Chie Wada -Mihara, Masami Ninomiya, 西川泰史, Jung-Hwan Lew, Koji Naruishi and Toshihiko Nagata : Diagnosis of Periodontal Diseases using Biomarkers in Gingival Crevicular Fluid, Journal of Oral Health and Biosciences, Vol.29, No.1, 13-20, 2016. (Summary) Periodontal diseases cause an inflammation and degradation of periodontal tissues and missing of teeth. The incidence rate of periodontal diseases is high in middle-aged and elderly people.A reasonable diagnosis of periodontal diseases is very important to keep teeth, however, conventional examinations of periodontal diseases is not necessarily exact and objective. Gingival crevicular fluid (GCF) is an exudate secreted from periodontal tissues and contains many components including proteolytic enzymes, inflammatory cytokines, blood-associated proteins, cellular and bacterial fragments. Because some proteins in GCF are related to inflammation, tissue degradation and bone metabolism, those proteins have been studying as a diagnostic marker of periodontal diseases. GCF is noninvasively collected using a sterile paper strip and biomarkers are determined using enzyme-linked immunosorbent assay (ELISA) and enzyme activity assay. We identified calprotectin, an inflammationrelated protein, in GCF and calprotectin level in GCF from periodontitis sites was significantly higher than that of healthy control. Calprotectin level in GCF was positively correlated to gingival index and other biomarkers and decreased by periodontal treatments. Resistin is an adipocytokine and its level increases in some inflammatory diseases. Resistin level in GCF from periodontitis sites was high compared to the level of healthy control samples. Procollagen type I C-terminal peptide (PICP) is a biomarker for bone metabolism and its level was high in GCF collected from periodontitis sites. These results suggested that calprotectin, resistin and PICP are useful biomarkers for periodontal diseases. On the other hand, we showed that glycated albumin (GA), a marker of diabetes mellitus (DM), was contained in GCF and GA level in GCF from DM patients was significantly higher than that of non-DM individuals. Components in GCF may be biomarkers of systemic diseases as well as periodontal diseases and their determination will be useful diagnostic examination of some diseases. Recently, we have been studying the determining system of GCF calprotectin, including microchip ELISA, surface plasmon resonance assay and immuno-chromatography assay. When GCF biomarkers are determined using the determining systems, we will simply, exactly and objectively diagnose periodontal diseases at our dental offices. (Keyword) 歯周病診断 / バイオマーカー / 歯肉溝滲出液 (Tokushima University Institutional Repository) ● Metadata: 109875 (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1050020697877556480 (Tokushima University Institutional Repository: 109875, CiNii: 1050020697877556480)
2.	Masami Ninomiya and Toshihiko Nagata : FGF-2による歯周組織再生療法, 歯の長期保存の臨床私はこうして歯を守る, Vol.38, No.6, 126-131, 2013. (Keyword) Periodontal regeneration / Fibroblast growth factor 2 / Clinical trial
3.	Masami Ninomiya : Periodontal Tissue Regeneration by Fibroblast Growth Factor-2, 31th Proceedings 臨床歯科を語る会, Vol.31, No.1, 28-33, 2011. (Keyword) Fibroblast Growth Factor-2 / Periodontal Tissue Regeneration / periodontal disease
4.	Seiichiro Kitamura, Masami Ninomiya and Youji Miyamoto : カラーアトラス:皮膚・粘膜の下，透けて見えますか, Dental Outlook, Vol.10, No.6, 2007.
5.	Masami Ninomiya, Kayoko Akazawa, Kazuhito Satomura, Nobuyuki Kamata, Masaru Nagayama, Keiji Moriyama, Jun-ichi Kido and Toshihiko Nagata : Hypercementosis with the progression of chronic apical periodontitis -A case report, Shikoku Dental Research, Vol.15, No.2, 263-269, 2003.

Academic Letter:

1.	Masami Ninomiya and Hiromichi Yumoto : A case of severe necrotizing ulcerative gingivitis with feeding difficulty, Weltec Information, 2024. (Keyword) periodontitis / Necrotizing ulcerative gingivitis / chlorhexidine
2.	Masami Ninomiya : 全顎的な歯肉腫脹, デンタルダイヤモンド, Vol.39, No.12, 133-134, 2014.

Review, Commentary:

1.	Masami Ninomiya : 上顎前歯口蓋歯肉の腫脹と排膿, DENTAL DIAMOND, Vol.49, No.8, 17-18, Jun. 2024. (Keyword) 鼻口蓋管嚢胞 / 歯根嚢胞
2.	Masami Ninomiya : 有病高齢者に発症した重度薬物性歯肉増殖症の症例, ウェルテックインフォメーション, Jun. 2023. (Keyword) Drug-induced gingival overgrowth / geriatric nursing / Mouthwash
3.	Hiromichi Yumoto, Keiko Aota and Masami Ninomiya : 歯肉頬移行部の腫瘤, DENTAL DIAMOND, Vol.47, No.1, 25-26, Jan. 2022. (Keyword) 歯肉腫瘤 / 脂肪種
4.	Kouji Hirao, Masami Ninomiya and Hiromichi Yumoto : X線写真で認められた根尖部透過像, DENTAL DIAMOND, Vol.45, No.662, 21-22, Apr. 2020.
5.	Masami Ninomiya, Tsutomu Iwamoto and Hiromichi Yumoto : 女児に認められた上顎前歯部の歯肉腫脹, DENTAL DIAMOND, Vol.44, No.4, 15-16, Mar. 2019. (Keyword) gingival fibromatosis
6.	Masami Ninomiya and Hiromichi Yumoto : 歯根側面に認められたX線透過像, DENTAL DIAMOND, Vol.43, No.4, 17-18, Mar. 2018. (Keyword) 垂直性歯根破折 / diagnostic imaging
7.	Masami Ninomiya : 歯周組織再生剤「リグロス」で広がる歯周治療の可能性, DENTAL DIAMOND, Vol.42, No.15, 57-71, Nov. 2017. (Keyword) FGF-2 / Periodontal regeneration
8.	Toshihiko Nagata, Masami Ninomiya, Chie Wada -Mihara, Jun-ichi Kido and Seiji Nishikawa : Etiology of drug-induced gingival overgrowth, Current Issues in Periodontics, 1-8, Oct. 2016. (Keyword) Drug-induced gingival overgrowth / epidemiology / Calcium-channel blocker
9.	Masami Ninomiya and Toshihiko Nagata : 全顎的な歯肉のびらん・接触痛, DENTAL DIAMOND, Vol.41, No.13, 19-20, Oct. 2016.
10.	Masami Ninomiya and Toshihiko Nagata : 下顎前歯部の動揺, DENTAL DIAMOND, Vol.40, No.15, 21-22, Nov. 2015. (Keyword) 侵襲性歯周炎 / 歯周治療
11.	Masami Ninomiya and Toshihiko Nagata : 下顎前歯部の歯肉腫脹, DENTAL DIAMOND, Vol.38, No.8, 133-134, Jun. 2013. (Keyword) Gingival swelling / Pathologic examination / Radicular cyst
12.	Toshihiko Nagata and Masami Ninomiya : 2.各論 1)歯周病 (特集透析患者の口腔衛生), 透析フロンティア, Vol.21, No.2, 12-16, May 2011.
13.	Seiichiro Kitamura, Kikuji Yamashita and Masami Ninomiya : 歯科医師・口腔外科医に必要な局所解剖学の知識6—口蓋と上顎骨—外科的処置に失敗しないために, Dental Outlook, Vol.110, No.6, 1046-1053, Dec. 2007.
14.	Seiichiro Kitamura, Masami Ninomiya and Youji Miyamoto : 口腔外科医に必要な局所解剖学の知識3口腔前庭—外科処置に失敗しないために, Dental Outlook, Vol.110, No.3, 458-465, Sep. 2007.
15.	Seiichiro Kitamura, Masami Ninomiya and Youji Miyamoto : 歯科医師・口腔外科医に必要な局所解剖学の知識3口腔前庭—外科処置に失敗しないために, Dental Outlook, Vol.110, No.3, 458-465, Sep. 2007.
16.	Hiroyuki Seto, Masami Ninomiya and Toshihiko Nagata : Alveolar bone resorption in animal models of periodontitis, CLINICAL CALCIUM, Vol.16, No.2, 24(248)-30(254), Jan. 2006.

Proceeding of International Conference:

1.	Masami Ninomiya, Keiji Oishi, Hashimoto Mari, Koji Naruishi, Yamanouchi Kouji, Fukumura Yoshiaki and Toshihiko Nagata : A Cross-Sectional Study on the Severity of Periodontitis in Infective Endocarditis Patients, 11th Asian Pacific Society of Periodontology Meeting, Oct. 2015. (Keyword) infective endocarditis / periodontitis / bone resorption / serum antibody titer / epidemiology
2.	Hiromi Murata, Masami Ninomiya, Takashiba Shogo, Maeda Hiroshi, Jun-ichi Kido and Toshihiko Nagata : A major neurodegenerative disease protein TDP-43 enhances TNF- transcriptional regulation in human monocyte-derived macrophage-like cells, 10th Asian Pacific Society of Periodontology Meeting, 42, Sep. 2013.
3.	Toshihiko Nagata, Jun-ichi Kido, Mika Bandou, Yuka Hiroshima, Yuji Inagaki, Masami Ninomiya, Chie Wada -Mihara, Hiromi Murata, Yukiko Bandou and Makoto Funaki : Diagnosis of diabetes-associated periodontitis by measuring biomarkers in gingival crevicular fluid, The 9th International Diabetes Federation Western Pacific Region Congress/ The 4th AASD Scientific Meeting, Nov. 2012.
4.	Masami Ninomiya, Satoshi Yoneda, Jun-ichi Kido and Toshihiko Nagata : Successful periodontal regeneration by FGF2. -A long-term follow-up case report-, The 96th Annual Meeting of American Academy of Periodontology in collaboration with the Japanease Society of Periodontology, USA, Hawaii, Oct. 2010.
5.	Masami Ninomiya, T Azuma, H Seto, J Kido and T Nagata : Successful Periodontal Regeneration Using FGF-2 in Two Periodontitis Patients, 2005-Sino-Japanese Conference on Stomatology, Shanghai, Nov. 2005.
6.	Masami Ninomiya : Periodontal Conditions in Patients with Diabetic Nephropathy, 89th the American Academy of Periodontology Annual Meeting, San Francisco, Sep. 2003.

Proceeding of Domestic Conference:

1.	Kido Kohei, Yano Yoshitaka, Goto Kuniyuki, Masami Ninomiya and Hiromichi Yumoto : The relationship between periodontal condition and red complex by a simple oral bacteria detection device orcoa, 第67回秋季日本歯周病学会学術大会プログラムおよび演題抄録集, Vol.66, 50, Oct. 2024. (Keyword) 歯周病 / Periodontal bacteria / Point of care testing
2.	Masami Ninomiya : Periodontal treatment for root furcation involvement, 歯周組織再生療法WEBセミナー, Aug. 2024. (Keyword) periodontitis / Furcation involvement / Periodontal regenerative therapy
3.	Masami Ninomiya : 歯科衛生士として知っておくべき慢性腎臓病患者のペリオドンタルメディシン, 日本歯周病学会第4回四国地区臨床研修会, Jun. 2024. (Keyword) periodontitis / Periodontal Medicine / Chronic Kidney Disease
4.	Yasufumi Nishikawa, Masami Ninomiya, Hiromichi Kawano, Yoritoki Tomotake and Hiromichi Yumoto : A case report of comprehensive periodontal treatment for a generalized chronic periodontitis patient without posterior occlusal support, 第67回春季日本歯周病学会学術大会プログラムおよび演題抄録集, Vol.66, 146, Apr. 2024. (Keyword) periodontitis / Chronic Periodontitis / Comprehensive periodontal treatment
5.	Yuta Uemura, Masami Ninomiya, Uemura Tomomi and Hiromichi Yumoto : A case report of periodontal regenerative therapy for a generalized chronic periodontitis (Stage Grade C) patient with diabetes mellitus and occlusal trauma, 第67回春季日本歯周病学会学術大会プログラムおよび演題抄録集, Vol.66, 56, Apr. 2024. (Keyword) periodontitis / diabetes mellitus / occlusal trauma
6.	Uemura Tomomi, Masami Ninomiya, Yuta Uemura and Hiromichi Yumoto : 長期喫煙歴のある広汎型重度慢性歯周炎患者に対してリグロスとサイトランスグラニュールを併用した歯周組織再生療法を行った一症例, 第67回春季日本歯周病学会学術大会プログラムおよび演題抄録集, Vol.66, 151, Apr. 2024. (Keyword) periodontitis / smoking / REGROTH
7.	Masami Ninomiya, Yuta Uemura and Hiromichi Yumoto : A case report of periodontal regenerative therapy using Regroth and CytransGranules for severe bone defect with combined periodontic-endodontic lesions, The 159th Meeting of the Japanese Society of Conservative Dentistry, 152, Nov. 2023. (Keyword) Combined periodontic-endodontic lesions / Periodontal regenerative therapy / Regroth / CytransGranules
8.	Yuta Uemura, Masami Ninomiya, Tomomi Uemura and Hiromichi Yumoto : A case of comprehensive periodontal treatment for a generalized aggressive periodontitis, 第66回秋季日本歯周病学会学術大会プログラムおよび演題抄録集, 178, Oct. 2023. (Keyword) Aggressive periodontitis / Periodontal regenerative therapy / Short roots
9.	Masami Ninomiya : リグロスを用いた歯周組織再生療法の実践テクニック -押さえておくべき手術手技と術前術後の管理-, 歯周治療×リグロス 2Days WEBセミナー, Sep. 2023. (Keyword) periodontitis / periodontal regenerative therapy / Regroth
10.	Tomomi Uemura, Yuta Uemura, Masami Ninomiya and Hiromichi Yumoto : 長期喫煙歴のある広汎型慢性歯周炎患者に対してリグロスとサイトランスグラニュールを併用した歯周組織再生療法を行った症例, 日本歯周病学会中国四国3大学・日本臨床歯周病学会中国四国支部合同研修会, Sep. 2023. (Keyword) smoking / Periodontal regenerative therapy / REGROTH / CytransGranules
11.	Masami Ninomiya, Takahisa Ikuta, AKIZUKI Minato, Yuta Uemura and Hiromichi Yumoto : PCRを用いたTreponeme denticola, Tannerella forsythia迅速検出システムの有用性, 日本歯科保存学会 2023年度春季学術大会(第158回)プログラムおよび講演抄録集, 142, Jun. 2023. (Keyword) 歯周病原細菌 / Point of Care Testing / Porphyromonas gingivalis / Treponeme denticola / Tannerella forsythia
12.	Masami Ninomiya : チーム医療で取り組む特殊な歯周病症例への対応, 第46回九州デンタルショー2023 生涯研修セミナー, Jun. 2023. (Keyword) periodontitis / チーム医療 / 医科歯科連携
13.	Masami Ninomiya : 難症例から学ぶ歯周病症例作成のポイント, Journal of the Japanese Society of Periodontology, Vol.65, No.April, 100, May 2023. (Keyword) periodontitis / 歯周病専門医 / 臨床症例
14.	Yuta Uemura, Masami Ninomiya, Tomomi Uemura and Hiromichi Yumoto : A case report of periodontal tissue regenerative therapy using REGROTH and CytransGranules in a patient with generalized severe periodontitis who had a smoking history, Journal of the Japanese Society of Periodontology, Vol.65, No.April, 165, May 2023. (Keyword) Periodontal regenerative therapy / REGROTH / CytransGranules / smoking
15.	Miwa Bando, Masami Ninomiya, Yasuda Katsuhiro and Hiromichi Yumoto : A case report of periodontal regenerative therapy using REGROTH and CytransGranules for lower right first molar with class furcation involvement, Journal of the Japanese Society of Periodontology, Vol.65, No.April, 165, May 2023. (Keyword) Periodontal regenerative therapy / REGROTH / CytransGranules / Furcation involvement
16.	Yasufumi Nishikawa, Yuta Uemura, Masami Ninomiya and Hiromichi Yumoto : A case of improvement in cleanability of peri-implant mucosa by free gingival graft, 第66回春季日本歯周病学会学術大会, Vol.65, No.April, 164, May 2023.
17.	Masami Ninomiya : 誰でもできる「リグロス」を用いた歯周組織再生療法, 東京松風歯科クラブ 2022年度オンライン月例会, Sep. 2022. (Keyword) Periodontal regenerative therapy / Regroth / Fibroblast growth facter 2
18.	Hiromichi Yumoto, Masami Ninomiya and Jun-ichi Kido : 骨格性不正咬合による矯正治療患者に対して包括的歯周治療を行った一症例, 第65回秋季日本歯周病学会学術大会(仙台), Sep. 2022.
19.	Masami Ninomiya : 歯周組織再生剤「リグロス」で目指す歯の長期保存ー治験から21年を迎えてー, 第65回秋季日本歯周病学会学術大会, Vol.64, 101, Sep. 2022. (Keyword) Periodontal regeneration therapy / periodontitis / Regroth / Fibroblast growth factor 2
20.	Yasufumi Nishikawa, Yuta Uemura, Hiromichi Kawano, Yoritoki Tomotake, Masami Ninomiya and Hiromichi Yumoto : Evaluation of mucosal thickness using digital image analysis after periodontal plastic surgery for peri-implant mucosa: A case report, 第65回春季日本歯周病学会学術大会プログラムおよび演題抄録集, Vol.64, 150, Jun. 2022. (Keyword) implant / Periodontal plastic surgery / Digital image analysis
21.	Akihiro Wada, Masami Ninomiya, Nobuyuki Kanazaki, Yuta Uemura and Hiromichi Yumoto : A case report of separation of artificial bone after periodontal regenerative therapy using artificial bone and Regroth for vertical bone defect, 第65回春季日本歯周病学会学術大会プログラムおよび演題抄録集, Vol.64, 146, Jun. 2022. (Keyword) periodontal regenerative therapy / fibroblast growth factor 2 / periodontitis / Regroth
22.	Masami Ninomiya : 歯周組織再生剤リグロスで目指す歯の長期保存ー治験から20年を向かえて-, 四国歯学会第59回例会, Mar. 2022. (Keyword) Periodontal regeneration therapy / Regroth / periodontitis
23.	Rie Kido, Eijiro Sakamoto, Yuka Hiroshima, Mika Bandou, Jun-ichi Kido, Takahisa Ikuta, Masami Ninomiya, Yuji Inagaki, Yasufumi Nishikawa, Yoritoki Tomotake, Koji Naruishi and Hiromichi Yumoto : イムノクロマト法を用いたカルプロテクチン測定による歯周病およびインプラント疾患の診断, 四国歯学会第59回例会, Mar. 2022.
24.	Masami Ninomiya : 今からでも間に合う歯周外科治療の基本, 保険診療で行う歯周外科治療ベーシックWebセミナー, Feb. 2022. (Keyword) periodontitis / Periodontal Surgery / リグロス
25.	Yasufumi Nishikawa, Masami Ninomiya, Hiromichi Kawano, Yoritoki Tomotake and Hiromichi Yumoto : 限局型侵襲性歯周炎患者に対してリグロスとサイトランスグラニュールを併用した歯周組織再生療法を行い1年半経過した1症例, 日本歯周病学会中国四国3大学・日本臨床歯周病学会中国四国支部合同研修会, Nov. 2021. (Keyword) Aggressive periodontitis / Regroth / サイトランスグラニュール
26.	Yasufumi Nishikawa, Koji Naruishi, Masami Ninomiya, Yuta Uemura and Hiromichi Yumoto : 2次性咬合性外傷を有する広汎型重度慢性歯周炎患者に包括的歯周治療を行った一症例, 日本歯科保存学会2021年度秋季学術大会(第155回)プログラムおよび講演抄録集, Oct. 2021. (Keyword) 侵襲性歯周炎
27.	Hiromichi Yumoto and Masami Ninomiya : A case of orthodontic treatment and periodontal surgery for a chronic periodontitis patient, 第64回秋季日本歯周病学会学術大会プログラムおよび演題抄録集, Vol.63, 154, Oct. 2021. (Keyword) 遺伝性疾患 / 歯周組織再生 / 小矯正
28.	Masami Ninomiya, Yuta Uemura, Minato Akizuki, Takahisa Ikuta and Hiromichi Yumoto : A case report of necrortizing ulcerative gingivitis that became severe after the common cold, 第64回秋季日本歯周病学会学術大会プログラムおよび演題抄録集, Vol.63, 161, Oct. 2021. (Keyword) Necrortizing ulcerative gingivitis / 免疫機能低下 / Common cold / 接触障害
29.	Hiromichi Yumoto, Masami Ninomiya and Jun-ichi Kido : 遺伝性疾患(ファブリー病)を有する慢性歯周炎患者に対して矯正治療と歯周外科治療を行った一症例, 第64回秋季日本歯周病学会学術大会, Oct. 2021.
30.	Masami Ninomiya : Periodontal medicine in patients with chronic kidney disease, The 39th Annual Meeting of the Japanese Academy of Clinical Periodontology, 34-35, Jul. 2021. (Keyword) periodontitis / Chronic kidney disease / Periodontal medicine
31.	Yasufumi Nishikawa, Masami Ninomiya, Hiromichi Kawano, Yoritoki Tomotake and Hiromichi Yumoto : A case report of the periodontal regeneration technique in combination with REGROTH and Cytrans Granules and implant treatment for a patient with localized aggressive periodontitis, 第64回春季日本歯周病学会学術大会プログラムおよび演題抄録集, Vol.63, 119, May 2021. (Keyword) periodontal regeneration technique / REGROTH / Cytrans Granules / periodontitis
32.	Takahisa Ikuta, Masami Ninomiya, 秋月皆人, Yuta Uemura, Koji Naruishi and Hiromichi Yumoto : Examination of the effectiveness of Porphyromonas gingivalis type 2 fimbria detection system by PCR, 第64回春季日本歯周病学会学術大会プログラムおよび演題抄録集, Vol.63, 24, May 2021. (Keyword) PCR / Porphyromonas gingivalis
33.	AKIZUKI Minato, Masami Ninomiya, Takahisa Ikuta, Yuta Uemura and Hiromichi Yumoto : チェアサイドでのPorphyromonas gingivalis迅速検出システムの有用性, 四国歯学会第57回例会, Mar. 2021. (Keyword) PCR検査 / 歯周病原細菌 / Porphyromonas gingivalis
34.	Masami Ninomiya : 人生100年時代を支えるリグロスによる歯周再生治療, 歯周組織再生療法 Webセミナー, Feb. 2021. (Keyword) Periodontal regeneration therapy / Regroth
35.	Masami Ninomiya : リグロスの効果を高める手技と長期予後 -骨補填材との併用効果-, 歯科再生医療研究会 Web講演会, Jan. 2021. (Keyword) Periodontal regeneration therapy / Regroth / 骨補填材
36.	AKIZUKI Minato, Masami Ninomiya, Yuta Uemura, Takahisa Ikuta, Koji Naruishi and Hiromichi Yumoto : Usefulness of rapid detection system of Porphyromonas gingivalis using PCR, 日本歯科保存学会第153回 2020年度秋季学術大会, Nov. 2020. (Keyword) periodontitis / Porphyromonas gingivalis / PCR / clinical laboratory testing
37.	Masami Ninomiya : 歯周感染で失われた歯槽骨をリグロスで治す -リグロスの効果と長期予後-, 第59回広島県歯科医学会併催第104回広島大学歯学会例会, Nov. 2020. (Keyword) Periodontal regeneration therapy / Regroth / Fibroblast growth factor 2
38.	Masami Ninomiya, Yuta Uemura, Akihiro Wada, Takahisa Ikuta and Hiromichi Yumoto : A case report of the periodontal regeneration therapy in combination with REGROTH and CytransGranules for a severe bone defect in mandibular first molar, Journal of the Japanese Association of Periodontology, Vol.62, 134, Oct. 2020. (Keyword) Periodontal regeneration therapy / Severe periodontitis / REGROTH / CytransGranules
39.	Masami Ninomiya : QOL向上につながる歯周治療ー歯周組織再生剤「リグロス」でここまで治るー, リグロス発売3周年記念歯周治療実践セミナー, Jul. 2020. (Keyword) Periodontal regeneration therapy / Regroth / quality of life
40.	植村勇太, Masami Ninomiya, 和田明大, Rie Kido, 高木亮輔, 野中康平, 谷口裕哉, Takahisa Ikuta, Eijiro Sakamoto, Mika Bandou, Yuji Inagaki, Koji Naruishi, Jun-ichi Kido and Hiromichi Yumoto : 歯周病ならびに歯周組織再生療法に関する臨床研究について, 徳島県歯科医学大会・四国歯学会第56回例会, Feb. 2020.
41.	Masami Ninomiya : 一からわかる「リグロス」を用いた歯周組織再生療法ー作用機序と有効性を高める手技ー, 兵庫県保険医協会歯科部会12月歯科定例研究会, Dec. 2019. (Keyword) periodontitis / Periodontal regeneration therapy / Regroth
42.	Ryosuke Takagi, Masami Ninomiya, Yuta Uemura and Hiromichi Yumoto : 中等度慢性歯周炎患者の幅広の骨内欠損に対しリグロスと骨補填材を併用した再生療法を行った一症例, 日本歯周病学会中国四国3大学・日本臨床歯周病学会中国四国支部合同研修会, Dec. 2019. (Keyword) periodontitis / Periodontal regeneration therapy / Regroth
43.	Masami Ninomiya, Takahisa Ikuta, Koji Naruishi and Hiromichi Yumoto : 重度慢性歯周炎を有する血液透析患者に対して包括的歯周治療を行った一症例, 日本歯科保存学会 2019年度秋季学術大会(第151回), Nov. 2019. (Keyword) periodontal disease / dialysis / Periodontal treatment / Periodontal medicine
44.	Masami Ninomiya : 歯周組織再生療法の変遷ー歯周組織再生剤「リグロス」でここまで治るー, 高松市歯科医師会第2回学術講演会, Oct. 2019. (Keyword) Periodontal regeneration therapy / Regroth / periodontitis
45.	Masami Ninomiya : 「リグロス」による歯周組織再生療法の効果ー有効性を高める手技と長期予後ー, 日本臨床歯周病学会第37回年次大会, 114, Jun. 2019. (Keyword) Periodontal regeneration therapy / Rigroth / Basic fibroblast growth factor / Alveolar bone
46.	Kanasaki Nobuyuki, Masami Ninomiya and Hiromichi Yumoto : A Case Report of Periodontal Tissue Regeneration Therapy for a Patient of Aggressive Periodontitis Proguressed during Orthdontic Treatment, Journal of the Japanese Association of Periodontology, Vol.61, 149, May 2019. (Keyword) Aggressive Periodontitis / Periodontal Regeneration Therapy / Education for Patients
47.	Masami Ninomiya, Eijiro Sakamoto, Koji Naruishi, Takahisa Ikuta, Ryosuke Takagi, Hatanaka Kazu, Okamoto Kentaro, Ono Shintaro, Takashiba Shogo and Hiromichi Yumoto : A Familial Case of Severe Periodontitis associated with Cyclic Neutropenia, Journal of the Japanese Association of Periodontology, Vol.61, 164, May 2019. (Keyword) Cyclic Neutropenia / Familial / Severe Periodontitis
48.	Masami Ninomiya : QOL向上のための歯周治療 -有病者や若年者の歯周病症例を通して-, 徳島大学大学院顎機能咬合再建学分野同門会学術講演, Mar. 2019. (Keyword) periodontitis / quality of life / Periodontal treatment
49.	Masami Ninomiya, Ikuta Takahisa, Koji Naruishi and Hiromichi Yumoto : A case report of comprehensive periodontal treatment for a patient with infective endocarditis caused by oral bacteria, 日本歯科保存学会2018年度秋季学術大会(第149回), 163, Nov. 2018. (Keyword) Infective endocarditis / Oral bacteria / Periodontal treatment
50.	Chie Wada -Mihara, Jun-ichi Kido, Masami Ninomiya and Hiromichi Yumoto : 薬物性歯肉増殖を伴う高齢の慢性歯周炎患者に対して包括的歯周治療を行った1症例, 第62回秋季日本歯周病学会学術大会, Oct. 2018.
51.	Chie Wada -Mihara, Jun-ichi Kido, Masami Ninomiya and Hiromichi Yumoto : A case report of comprehensive treatment for an elderly patient of chronic periodontitis with drug-induced gingival overgrowth, 第61回秋季日本歯周病学会学術大会, Vol.60, 153, Oct. 2018. (Keyword) Drug-induced gingival overgrowth / Calcium channel blockers / Chronic periodontitis
52.	Masami Ninomiya : 歯周組織再生療法の変遷ー骨移植術からリグロスまで-, 平成30年度鶴見大学歯学部補綴科全体症例会, Oct. 2018. (Keyword) Periodontal regeneration / Regroth
53.	Masami Ninomiya : 2時間でわかる歯周組織再生療法とその魅力-新規医薬品「リグロス」の有効性-, 香川県歯科医師会香川デンタルスタディグループ, Aug. 2018. (Keyword) Periodontal regeneration / Regroth / Basic fibroblast growth factor
54.	Masami Ninomiya : FGF-2製剤を用いた歯周病治療最前線ー新規医薬品「リグロス」は本当に効くのか-, 大津市歯科医師会平成30年度第2回学術講演会, Jul. 2018. (Keyword) Periodontal regeneration / FGF-2 / Regroth
55.	Masami Ninomiya : 1時間でわかる歯周病治療最前線ー新規歯周組織再生剤「リグロス」の作用機序と効果-, 徳友会学術講演, Jun. 2018. (Keyword) Periodontal regeneration / Regroth
56.	Takekawa Kaori, Masami Ninomiya, Toshihiko Nagata and Hiromichi Yumoto : A case report of initial periodontal therapy for severe drug-induced gingival overgrowth with cardiovascular disease, Journal of the Japanese Association of Periodontology, Vol.60, 162, Jun. 2018. (Keyword) Drug-induced gingival overgrowth / Initial periodontal therapy / Cardiovascular disease
57.	Rie Kido, Eijiro Sakamoto, Mika Bandou, Yuji Inagaki, Masami Ninomiya, Chie Wada -Mihara, Takahisa Ikuta, Koji Naruishi, Toshihiko Nagata, Jun-ichi Kido and Hiromichi Yumoto : インプラント周囲溝滲出液中のカルプロテクチンとNTxを用いたインプラント疾患の診断, 第61回春季日本歯周病学会学術大会, Jun. 2018.
58.	Masami Ninomiya : 歯周再生治療におけるFGF-2製剤の有効性, 徳島県歯科医師会スタディグループ新木会, Dec. 2017. (Keyword) Basic fibroblast growth factor / Periodontal regeneration therapy
59.	Chie Wada -Mihara, Masami Ninomiya, Jun-ichi Kido and Toshihiko Nagata : 降圧薬由来の歯肉増殖を伴う重度歯周炎患者に対する歯周治療の効果, 日本歯周病学会中国四国3大学・日本臨床歯周病学会中国四国支部合同研修会, Nov. 2017. (Keyword) Antihypertensive drug / Drug-induced gingival hyperplasia / periodontitis
60.	Masami Ninomiya : FGF-2製剤による歯周サイトカイン療法ー新規医薬品「リグロス」は本当に効くのかー, 日本歯周病学会中国四国3大学・日本臨床歯周病学会中国四国支部合同研修会, Nov. 2017. (Keyword) Fibroblast growth factor 2 / Periodontal regeneration terapy / periodontitis / Regroth
61.	Yukari Kajiura, Masami Ninomiya, Ikuta Takahisa, HWAN JUNG LEW, Jun-ichi Kido and Toshihiko Nagata : A case report of radicular cysts in maxillary both lateral incisors, 日本歯科保存学会2017年度秋季学術大会(第147回), Oct. 2017. (Keyword) Radicular cyst / Chronic apical periodontitis / Cystectomy / multiple
62.	Masami Ninomiya : FGF-2製剤を用いた新規歯周組織再生療法ーリグロス歯科用液キットの有効性ー, 徳島県歯科医師会スタディグループ歯科塾, Oct. 2017. (Keyword) Basic fibroblast growth factor / Periodontal Regeneration Therapy
63.	Masami Ninomiya : 2時間でわかる歯周病治療最前線とその魅力ー歯周再生療法を中心にー, 平成29年度徳島大学歯学部同窓会関東支部学術講演, Aug. 2017. (Keyword) periodontitis / periodontal regeneration
64.	Masami Ninomiya : 保険導入されたFGF-2製剤による新規歯周組織再生療法ーリグロス歯科用液キットの有効性ー, 愛媛県歯科医師会学術講演, Jul. 2017. (Keyword) fibroblast growth factor 2 / periodontal regeneration / periodontitis
65.	Masami Ninomiya, Yuji Inagaki, Chie Wada -Mihara, Mika Bandou, Yukiko Nakajima, Eijiro Sakamoto, Ikuta Takahisa, Nishikawa Yasufumi, Jung-Hwan Lew, Rie Kido, Takagi Ryousuke, Nonaka Kouhei, Koji Naruishi, Jun-ichi Kido and Toshihiko Nagata : 新規歯周組織再生剤「リグロス歯科用液キット」の有効性, 四国歯学会第51回例会, Jun. 2017. (Keyword) periodontitis / fibroblast growth factor 2 / periodontal regeneration / Regroth
66.	Chie Wada -Mihara, Koji Naruishi, Mika Bandou, 西川泰史, Hwan Jung Lew, Eijiro Sakamoto, 生田貴久, 河野薫, Yukari Kajiura, 橋本万里, Yukiko Nakajima, Yuji Inagaki, Masami Ninomiya, Jun-ichi Kido and Toshihiko Nagata : アドバンスドOSCEを見据えた当科の模擬OSCEの概要, Shikoku Dental Research, Vol.29, No.2, 49-53, Jun. 2017.
67.	Masami Ninomiya, Yukari Kajiura and Toshihiko Nagata : A case report of comprehensive periodontal treatment of severe drug-induced gingival overgrowth with malaligned teeth, 日本歯周病学会雑誌, Vol.59, 158, May 2017. (Keyword) drug-induced gingival overgrowth / calcium channel blocker
68.	Masami Ninomiya : FGF-2製剤を用いた新規歯周組織再生療法, 平成28年度徳島県歯科医師会学術講演, Feb. 2017. (Keyword) periodontitis / fibroblast growth factor 2 / periodontal regeneration
69.	Masami Ninomiya : 歯周疾患の治療計画ーQOL向上のための歯周治療ー, 松本歯科大学特別講演, Dec. 2016. (Keyword) periodontitis / Periodontal treatment / quality of life
70.	Masami Ninomiya, Jun-ichi Kido and Toshihiko Nagata : Long-term follow-up case reports for over 10-year after periodontal regeneration by FGF-2, The Journal of the Japan Dental Association, Vol.69, No.5, 137, Oct. 2016. (Keyword) fibroblast growth factor 2 / periodontal regeneration / long-term follow-up case
71.	美原智恵, Koji Naruishi, Mika Bandou, 西川泰史, Jung-Hwan Lew, Eijiro Sakamoto, 生田貴久, 河野薫, Yukari Kajiura, 橋本万里, Yukiko Nakajima, Yuji Inagaki, Masami Ninomiya, Jun-ichi Kido and Toshihiko Nagata : アドバンスOSCEを見据えた当科の模擬OSCEの概要, 第49回四国歯学会例会, Jun. 2016.
72.	Yukari Kajiura, Masami Ninomiya, Kono Kaoru and Toshihiko Nagata : The evaluation of periodontal pathogens in a patient with localized aggressive periodontitis which progressed after the childbirth, Journal of the Japanese Association of Periodontology, Vol.58, 161, May 2016. (Keyword) aggressive periodontitis / bacteriological examination / serum antibody titer / periodontal surgery
73.	Hashimoto Mari, Masami Ninomiya, Tetsuya Kitagawa and Toshihiko Nagata : 感染性心内膜炎の既往のある慢性歯周炎患者に対して歯周治療によりQOL向上を図った症例, 日本歯周病学会中国四国3大学・日本臨床歯周病学会中国四国支部合同研修会, Oct. 2015. (Keyword) Infective endocarditis / periodontitis / Periodontal bacteria / Serum antibody titer
74.	Masami Ninomiya : 歯周組織再生療法の変遷ーQOL向上のための歯周治療ー, 松本歯科大学歯周病学特別講義, Jul. 2015. (Keyword) periodontitis / Periodontal tissue regeneration / QOL
75.	Masami Ninomiya : QOL向上のための歯周治療, 道東歯学研究会・釧路歯科医師会共催講演, Jun. 2015. (Keyword) periodontitis / Periodontal medicine / QOL
76.	Masami Ninomiya, Hashimoto Mari and Toshihiko Nagata : A case report that improved the quality of life by comprehensive periodontal treatment for a hemodialysis patient with severe chronic periodontitis, 第58回春季日本歯周病学会学術大会, Vol.57, No.May, 139, May 2015. (Keyword) Renal failure / Hemodialysis / Chronic periodontitis
77.	Yukihiro Momota, Maki Hosoki, Masami Ninomiya, Hideyuki Takano, Yoshizo Matsuka and Masayuki Azuma : 口腔ならびに呼吸器症状を伴った歯科用金属によるアレルギーの1例, 第69回日本口腔科学会学術集会, May 2015.
78.	Masuda Yuri, Inagaki Koji, Masami Ninomiya, Kono Takayuki, Toshihiko Nagata and Mitani Akio : A team approach to a case of aggressive periodontitis with pregnancy, 第9回日本歯周病学会中部地区大学・日本臨床歯周病学会中部支部合同研究会, Nov. 2014. (Keyword) aggressive periodontitis / periodontal initial treatment / pregnancy / team approach
79.	Masami Ninomiya and Toshihiko Nagata : HIV/HCV重複感染血友病患者に対する包括的歯周治療によりQOL向上を図った一症例, 日本歯周病学会中国四国3大学・日本臨床歯周病学会中国四国支部合同研修会, Nov. 2014. (Keyword) HIV/HCV重複感染 / 血友病 / 包括的歯周治療 / ペリオドンタルメディシン
80.	Masami Ninomiya, Keiji Oishi, Hashimoto Mari, Koji Naruishi and Toshihiko Nagata : A Cross-Sectional Study on the Progression of Periodontitis in Infective Endocarditis Patients, 日本歯科保存学会 2014年度秋季学術大会(第141回), Oct. 2014. (Keyword) Infective Endocarditis / periodontitis / epidemiology
81.	Masami Ninomiya : 歯周組織再生療法の変遷, 松本歯科大学歯周病学特別講演, Jul. 2014.
82.	Yukari Kajiura, Mika Bandou, Jun-ichi Kido, Yuji Inagaki, 生田貴久, 橋本万里, 篠原宏貴, Masami Ninomiya, Hiromi Murata, Yukiko Nakajima, Satoshi Yoneda, 美原智恵, Yuka Hiroshima, Keiji Oishi and Toshihiko Nagata : 歯肉溝滲出液中のグリコアルブミンおよびカルプロテクチンを指標とした糖尿病関連歯周炎の診断, 第57回春季日本歯周病学会学術大会, May 2014.
83.	Hashimoto Mari, Masami Ninomiya and Toshihiko Nagata : A case report of chronic periodontitis with the history of infective endocariditis, Journal of the Japanese Association of Periodontology, Vol.56, 51, May 2014. (Keyword) Infective endocariditis / Chronic periodontitis / Serum antibody
84.	Hiromi Murata, Masami Ninomiya and Toshihiko Nagata : 侵襲性歯周炎患者に対して自家歯牙移植による咬合の回復を行った一症例, 日本歯周病学会第3回四国地区臨床研修会, 39, Apr. 2014. (Keyword) 侵襲性歯周炎 / 自家歯牙移植 / 歯周治療
85.	Masami Ninomiya : 腎臓病患者のペリオドンタルメディシン, 日本歯周病学会第3回四国地区臨床研修会, 24-26, Apr. 2014. (Keyword) Chronic Kidney Disease / periodontitis / Periodontal Medicine
86.	Masami Ninomiya : A case report of comprehensive periodontal treatments for generalized aggressive periodontitis in two sisters, 薫風会臨床セミナー, Mar. 2014. (Keyword) aggressive periodontitis / familiar
87.	Masami Ninomiya and Toshihiko Nagata : A case report of generalized aggressive periodontitis in two sisters, 日本歯周病学会中国四国3大学・日本臨床歯周病学会中国四国支部合同研修会, Oct. 2013. (Keyword) Aggressive periodontitis / family / Comprehensive treatment / 細菌検査 / 血清抗体価検査
88.	Masami Ninomiya : 侵襲性歯周炎の病態と治療, 四国歯学会第43回例会, Jun. 2013. (Keyword) Aggressive periodontitis / Familial / Periodontal treatment
89.	Masami Ninomiya : Periodontal Regeneration Therapy by FGF-2, 日本歯科大学新潟生命歯学部同門会講演, Jun. 2013. (Keyword) Periodontal Regeneration Therapy / FGF-2
90.	Masami Ninomiya, Mika Bandou, Hiromi Murata, Takahisa Ikuta, Jun-ichi Kido and Toshihiko Nagata : A case report of comprehensive periodontal treatments for generalized aggressive periodontitis in two sisters, Journal of the Japanese Association of Periodontology, Vol.55, Jun. 2013. (Keyword) Aggressive periodontitis / family / Periodontal Treatment
91.	Masami Ninomiya : Periodontal tissue regeneration by FGF-2, 鈴鹿歯科医師会学術講演会, Jan. 2013. (Keyword) Periodontal tissue regeneration / Fibroblast growth factor-2
92.	Masami Ninomiya and Toshihiko Nagata : A long-term follow-up case report of drug-induced gingival overgrowth appeared in a renal transplant recipient, 日本歯科保存学会2012年度秋季学術大会(第137回), 135, Nov. 2012. (Keyword) Drug-induced gingival overgrowth / Renal transplant / Cyclosporin
93.	Tomoko Azuma, 東秀樹, Masami Ninomiya and Toshihiko Nagata : A case report of periodontal surgery and orthodontic therapy for severe chronic periodontitis with flared anterior teeth, Journal of the Japanese Association of Periodontology, Vol.54, Sep. 2012. (Keyword) Severe periodontitis / Periodontal surgery / Orthodontic therapy
94.	Masami Ninomiya, Ikuta Takahisa and Toshihiko Nagata : A Case Report of Expanded Radicular Cyst in Mandible Anterior Teeth, 日本歯科保存学会 2012年度春季学術大会(第136回), Jun. 2012. (Keyword) Radicular Cyst / Biopsy / 嚢胞摘出術
95.	薫廣瀬, Masami Ninomiya and Toshihiko Nagata : Oral care management of a mentally retarded patient with the history of infective endocarditis, Journal of the Japanese Association of Periodontology, Vol.54, May 2012. (Keyword) Infective endocarditis / Mentally retarded patient / Periodontal initial therapy
96.	Hiromi Murata, Masami Ninomiya and Toshihiko Nagata : A successful case of autotransplantation and flap surgery performed to generalized aggressive periodontitis, Journal of the Japanese Association of Periodontology, Vol.54, May 2012. (Keyword) Aggressive periodontitis / Autotransplantation / Periodontal surgery
97.	Masami Ninomiya : Periodontal Tissue Regeneration by FGF-2, 日本臨床歯周病学会北海道支部春季教育研修会, Apr. 2012. (Keyword) Fibroblast growth factor-2 / Periodontal tissue regeneration / periodontal disease
98.	Jun-ichi Kido, Yuji Inagaki, Mika Bandou, Yuka Hiroshima, Hiromi Murata, Chie Wada -Mihara, Masumi Horibe, Satoshi Yoneda, Masami Ninomiya, Keiji Oishi, Eijiro Sakamoto, 中島由紀子, 生田貴久, 浅原洋士 and Toshihiko Nagata : バイオマーカーを用いた糖尿病関連歯周炎の診断研究, Journal of the Japanese Association for Dental Science, Vol.31, 86, Mar. 2012. (Keyword) *生物学的マーカー
99.	Jun-ichi Kido, Yuji Inagaki, Mika Bandou, Yuka Hiroshima, Hiromi Murata, Chie Wada -Mihara, Masumi Horibe, Satoshi Yoneda, Masami Ninomiya, Keiji Oishi, Eijiro Sakamoto, 中島由紀子, 生田貴久, 浅原洋士 and Toshihiko Nagata : バイオマーカーを用いた糖尿病関連歯周炎の診断研究, Journal of the Japanese Association for Dental Science, Vol.31, 86, Mar. 2012. (Keyword) *生物学的マーカー
100.	Jun-ichi Kido, Yuji Inagaki, Mika Bandou, Yuka Hiroshima, Hiromi Murata, Chie Wada -Mihara, Masumi Horibe, Satoshi Yoneda, Masami Ninomiya, Keiji Oishi, 坂本英次郎, 中島由紀子, 生田貴久, 浅原洋士 and Toshihiko Nagata : バイオマーカーを用いた糖尿病関連歯周炎の診断研究, Journal of the Japanese Association for Dental Science, Vol.31, 86, Mar. 2012. (Keyword) *生物学的マーカー
101.	Masami Ninomiya : 歯周組織再生療法の実際, 香川県歯科医師会, Dec. 2011. (Keyword) Periodontal Tissue Regeneration / periodontal disease / Growth Factor
102.	Masami Ninomiya and Toshihiko Nagata : A case report of comprehensive treatment focusing on initial periodontal therapy for a patient with hemophilia B and HIV/HCV co-infection, Journal of the Japanese Association of Periodontology, Vol.53, 139, Sep. 2011. (Keyword) HIV/HCV co-infection / hemophilia / periodontal disease
103.	Mika Bandou, Yuji Inagaki, Jun-ichi Kido, Yuka Hiroshima, Masatoshi Kataoka, Hiromi Murata, Yukiko Bandou, Masami Ninomiya, Eijiro Sakamoto, 中島由紀子 and Toshihiko Nagata : 歯肉溝滲出液中のグリコアルブミン測定法の確立, 日本歯周病学会会誌春季特別号, Vol.53, 119, May 2011. (Keyword) periodontitis / diabetes mellitus / 歯肉溝滲出液 / グリコアルブミン
104.	Mika Bandou, Yuji Inagaki, Jun-ichi Kido, Yuka Hiroshima, Masatoshi Kataoka, Hiromi Murata, Yukiko Bandou, Masami Ninomiya, 坂本英次郎, 中島由紀子 and Toshihiko Nagata : 歯肉溝滲出液中のグリコアルブミン測定法の確立, 日本歯周病学会会誌春季特別号, Vol.53, 119, May 2011. (Keyword) periodontitis / diabetes mellitus / 歯肉溝滲出液 / グリコアルブミン
105.	Yuka Sogawa, Masami Ninomiya, Tomoko Azuma and Toshihiko Nagata : 急性骨髄性白血病の骨髄移植後に発症した移植片対宿主病患者に対し口腔衛生管理を行った一症例, 日本歯周病学会雑誌, Vol.53, 149, Apr. 2011. (Keyword) 急性骨髄性白血病 / 移植片対宿主病(GVHD) / 口腔衛生管理
106.	Eijiro Sakamoto, Masami Ninomiya, Satoshi Yoneda, Tokunaga Kaku, Nakajima Yukiko, Javkhlan Purevjav, Takeda Yoko, Takemura Akane and Toshihiko Nagata : Inhibitory Effects of L-Cysteine on Alveolar Bone Resorption in Hamster Experimental Periodontitis, Shikoku Dental Research, Vol.23, No.2, 141, Jan. 2011. (Keyword) periodontal disease / L-Cysteine / Alveolar Bone
107.	Sakamoto Eijiro, Masami Ninomiya, Satoshi Yoneda, Tokunaga Kaku, Nakajima Yukiko, Javkhlan Purevjav, Takeda Yoko, Takemura Akane and Toshihiko Nagata : Inhibitory Effects of L-Cysteine on Alveolar Bone Resorption in Hamster Experimental Periodontitis, Shikoku Dental Research, Vol.23, No.2, 141, Jan. 2011. (Keyword) periodontal disease / L-Cysteine / Alveolar Bone
108.	Yuji Inagaki, Jun-ichi Kido, 板東美香, 廣島佑香, 片岡正俊, 美原智恵, 堀部ますみ, Satoshi Yoneda, Eijiro Sakamoto, 中島由紀子, Masami Ninomiya, 大石慶二, 浅原洋士 and Toshihiko Nagata : 糖尿病関連歯周炎における歯肉溝滲出液中のバイオマーカーの分析, 第53回日本糖尿病学会年次学術集会 (岡山), May 2010.
109.	Yuji Inagaki, Jun-ichi Kido, 板東美香, 廣島佑香, 片岡正俊, 美原智恵, 堀部ますみ, Satoshi Yoneda, 坂本英次郎, 中島由紀子, Masami Ninomiya, 大石慶二, 浅原洋士 and Toshihiko Nagata : 糖尿病関連歯周炎における歯肉溝滲出液中のバイオマーカーの分析, 第53回日本糖尿病学会年次学術集会 (岡山), May 2010.
110.	Jun-ichi Kido, Yuji Inagaki, Mika Bandou, Yuka Hiroshima, Masatoshi Kataoka, Chie Wada -Mihara, Masumi Horibe, Satoshi Yoneda, 坂本英次郎, 中島由紀子, Masami Ninomiya, Keiji Oishi, 淺原洋士 and Toshihiko Nagata : 歯肉溝浸出液中の糖尿病関連歯周炎バイオマーカーの検索, Journal of the Japanese Association of Periodontology, Vol.52, 97, May 2010.
111.	Masami Ninomiya, Satoshi Yoneda, 坂本英次郎, 中島由紀子, 徳永格, Javkhlan Purevjav, 竹田洋子, 江口徹, 武村あかね and Toshihiko Nagata : ハムスター実験的歯周炎モデルにおけるL-システインの歯槽骨吸収抑制効果, 日本歯科保存学会雑誌, Vol.53, 42, May 2010.
112.	Masami Ninomiya, Satoshi Yoneda and Toshihiko Nagata : A case report of comprehensive treatment with FGF-2 periodontal regenerative therapy and autotransplantation for chronic periodontitis, 日本歯周病学会雑誌, Vol.52, 132, May 2010. (Keyword) 慢性歯周炎 / 歯周組織再生療法 / 自家歯牙移植
113.	Yuji Inagaki, Jun-ichi Kido, Mika Bandou, Yuka Hiroshima, Masatoshi Kataoka, Chie Wada -Mihara, Masumi Horibe, Satoshi Yoneda, 坂本英次郎, 中島由紀子, Masami Ninomiya, Keiji Oishi, 淺原洋士 and Toshihiko Nagata : 糖尿病関連歯周炎における歯肉溝滲出液中のバイオマーカーの分析, Journal of the The Japan Diabetes Society, Vol.53, No.Suppl.1, S-145, Apr. 2010. (Keyword) 生物学的マーカー
114.	Keiji Oishi, Masumi Horibe, Masami Ninomiya and Toshihiko Nagata : Usefulness of a new parameter "Total Bone Resorption" representing the severity of periodontal tissue breakdown: the association with the severity of diabetes, Journal of the Japanese Association of Periodontology, Vol.52, 119, Apr. 2010.
115.	Eijiro Sakamoto, Masami Ninomiya, Satoshi Yoneda, 徳永格, 中島由紀子, フルジャフジャフラン, Katsuhiko Hirota, Yoichiro Miyake, 竹田洋子, 武村あかね and Toshihiko Nagata : ハムスター実験的歯周炎におけるL-Cysteinの歯槽骨吸収抑制効果, 四国歯学会第36回例会, Mar. 2010.
116.	坂本英次郎, Masami Ninomiya, Satoshi Yoneda, 徳永格, 中島由紀子, フルジャフジャフラン, Katsuhiko Hirota, Yoichiro Miyake, 竹田洋子, 武村あかね and Toshihiko Nagata : ハムスター実験的歯周炎におけるL-Cysteinの歯槽骨吸収抑制効果, 四国歯学会第36回例会, Mar. 2010.
117.	Mika Bandou, Yuka Hiroshima, Yuji Inagaki, Masatoshi Kataoka, Chie Wada -Mihara, Masumi Horibe, Satoshi Yoneda, Keiji Oishi, Masami Ninomiya, Javkhlan Purevjav, Jun-ichi Kido and Toshihiko Nagata : 糖尿病関連歯周炎における歯肉溝浸出液中バイオマーカーの分析, Journal of the Japanese Association of Periodontology, Vol.51, 101, Oct. 2009.
118.	Kikuji Yamashita, Tatsuo Ishikawa, Kaori Sumida, 安部佳織, Masami Ninomiya and Seiichiro Kitamura : コラーゲン内に形成される石灰化石灰化微粒子の検出, 平成20年度厚生労働省科学研究費等「ナノ微粒子の体内動態可視他法の開発」冬季研究班研究成果発表会, Feb. 2009.
119.	Masami Ninomiya and Toshihiko Nagata : Two Case Reports of Excessive Hypercementosis Associated with Chronie Apieal Periodontitis, 日本歯科保存学会2005年度春季学会(第122回), Vol.48, 197, Jun. 2005.
120.	Masami Ninomiya and Toshihiko Nagata : Two Case Reports of Autotransplantation Using Enamel Matrix Derivative, 日本歯科保存学会2004年度秋季学会(第121回), Vol.47, 228, Nov. 2004.
121.	Keiko Tsuji, Shinya Horiuchi, Masami Ninomiya, Toshihiko Nagata and Keiji Moriyama : A case of bilateral cleft lip and palate patient with osteoporosis treated by orthodonticperiodontic approach, 第63回日本矯正歯科学会大会, 302, Nov. 2004.
122.	Hiroyuki Seto, Masami Ninomiya, 和田智恵, 福本善和, 片岡正俊, Jun-ichi Kido and Toshihiko Nagata : Ca拮抗薬による歯肉増殖症の病態と治療, 第20回日本歯科医学会総会, Vol.57, No.4, 99, Oct. 2004.
123.	Tomoko Azuma, Masami Ninomiya, Hideki Azuma and Toshihiko Nagata : A case report of a tooth replantation using Emdogain Gel, 第47回秋季日本歯周病学会学術大会, 164, Oct. 2004. (Keyword) 再植 / エムドゲインゲル / 歯根膜
124.	Masami Ninomiya, Hiroyuki Seto, Jun-ichi Kido and Toshihiko Nagata : Phase \|\| Clinical Trial of Periodontal Regenerarion by KCB-1D(FGF-2), --- A Successful Case Report of Periodontal Regeneration by KCB-1D(FGF-2) ---, 第47回秋季日本歯周病学会学術大会, Oct. 2004. (Keyword) 塩基性線維芽細胞増殖因子(FGF-2) / 歯周組織再生 / 治験
125.	Hideki Hama, Hideki Azuma, Hiroyuki Seto, Masami Ninomiya, Keiji Oishi, Jun-ichi Kido and Toshihiko Nagata : エナメルマトリックス蛋白による骨芽細胞分化抑制作用および活性型TGF-βの関与, Journal of the Japanese Association of Periodontology, Vol.46, 114, May 2004. (Keyword) エナメルマトリックス蛋白 / osteoblast / differentiation / 活性型TGF-β
126.	Nobuyuki Kamata, Satoshi Tutumi, Yutaka Maruoka, Koichi Nakakuki, Masami Ninomiya, Yuji Kabasawa, Syunpei Yamada, Kazuto Kurohara, Ken Omura, Teruo Amagasa, Toshihiko Nagata, Masaru Nagayama and Mitsuo Itakura : 顎骨の骨およびセメント質形成病変における遺伝子変異検索, The 58th Annual Meeting of The Japanese Stomatological Society, 132, May 2004.
127.	Masami Ninomiya, Jun-ichi Kido and Toshihiko Nagata : A Case Report of Cyclosporin A-induced Gingival Overgrowth Observed in a Patient with Aplastic Anemia, 日本歯科保存学会2003年度秋季学会(第119回), Vol.46, 206, Nov. 2003.
128.	Tomoko Azuma, Gota Cho, Keizo Suzuki, Kaya Yoshida, Masumi Horibe, Teruo Nakamura, Masami Ninomiya, Keiji Oishi, Jun-ichi Kido and Toshihiko Nagata : 糖尿病性腎症患者の歯周病罹患に関する疫学的研究, Journal of the Japanese Association of Periodontology, Apr. 2003. (Keyword) 糖尿病性腎症 / 人工透析 / CPITN
129.	Masami Ninomiya and Toshihiko Nagata : A Case of the Patient with Malalignment Following Severe Nifedipine-induced Gingival Overgrowth, 第46回秋季日本歯周病学会学術大会, 170, Apr. 2003. (Keyword) ニフェジピン歯肉増殖症 / 歯周外科 / MTM
130.	Masami Ninomiya, Akane Takemura and Toshihiko Nagata : 骨代謝に視点をおいた歯周病治療薬の開発と展望, 第46回秋季日本歯周病学会学術大会, 47, Apr. 2003.
131.	Tae Usami, Masami Ninomiya and Toshihiko Nagata : A Study on the Surface Scratch of Ceramic Sharpening Stones, 第45回秋季日本歯周病学会学術大会, 215, Oct. 2002. (Keyword) セラミックストーン / シャープニング / 器具のメインテナンス
132.	Hideki Hama, Mika Oishi, Masami Ninomiya, Masatoshi Kataoka and Jun-ichi Kido : Expression of Cbfa1 on rat clonal dental pulp cells in culture, 日本歯科保存学会 2001年度秋季学会(第115回), Vol.44, 37, Nov. 2001.
133.	Masami Ninomiya, Noriyuki Yamauchi, Jun-ichi Kido and Toshihiko Nagata : A case Report of Multiple Hypercementosis Observed in Whole Mandibular Teeth, 第44回秋季日本歯周病学会学術大会, 176, Oct. 2001. (Keyword) セメント質過形成 / 家族性疾患 / 骨系統疾患
134.	A Takemura, Masami Ninomiya, T ohba, K Kunikiyo, H Azuma, H Hama, (名) Suryono, H Shinohara, Jun-ichi Kido and Toshihiko Nagata : Effects of novel MMP inhibitor on experimental periodontitis in hamsters, 79th International Association for Dental Research(LADR), Jun. 2001.
135.	Nobuyuki Kamata, Masami Ninomiya, Tomoko Azuma, 藤本良一, Toshihiko Nagata and Masaru Nagayama : 智歯·埋伏歯の移植歯への応用, 四国歯学会第25回例会·第20回総会, Jun. 2001.
136.	Nobuyuki Kamata, Masami Ninomiya, 藤本良一, 友成真弓, Toshihiko Nagata and Masaru Nagayama : 智歯·埋伏歯の移植術へのエムドゲインの応用, 第55回日本口腔科学会総会, Apr. 2001.

Et cetera, Workshop:

1.	Hiromichi Yumoto and Masami Ninomiya : Drug-induced gingival overgrowth, 健康と生活, No.546, Sep. 2023. (Keyword) periodontitis / side effects
2.	Masami Ninomiya : 歯周組織再生剤リグロスの効果的な使用方法と骨補填材との併用効果, 科研製薬株式会社協賛綾の会特別研修会, Mar. 2023.
3.	Masami Ninomiya, Eijiro Sakamoto, Koji Naruishi and Hiromichi Yumoto : 周期性好中球減少症患者に発症した重度歯周炎の家族症例, 第1回侵襲性歯周炎センタークリニカルカンファレンス, Dec. 2018. (Keyword) Cyclic Neutropenia / periodontal disease / Periodontal treatment
4.	Masami Ninomiya and Toshihiko Nagata : 歯根側面に認められたX線透過像, DENTAL DIAMOND, Vol.37, No.5, 119-120, Apr. 2012. (Keyword) Root Flacture / diagnostic imaging
5.	Masami Ninomiya and Toshihiko Nagata : FGF-2による再生療法, 臨床歯科を語る会シンポジウム, Jul. 2011. (Keyword) FGF-2 / 歯周組織再生療法 / 治験
6.	Masami Ninomiya and Toshihiko Nagata : 口腔内全体にわたる歯肉のびらん, Dental Diamond, Vol.36, No.5, 139-140, Apr. 2011.
7.	Masami Ninomiya, Satoshi Yoneda, Masumi Horibe, 美原智恵, Yuji Inagaki, Keiji Oishi, Jun-ichi Kido and Toshihiko Nagata : FGF-2による歯周組織再生療法, 第10回徳島Bone Forum, Dec. 2010. (Keyword) FGF-2 / 歯周組織再生療法 / 治験
8.	Masami Ninomiya : 自家歯牙移植の理論と術式, 第14回薫風会臨床セミナー, Nov. 2004.

Grants-in-Aid for Scientific Research (KAKEN Grants Database @ NII.ac.jp)

Development of a novel therapeutic approach targeting gingipain for regression phenomenon in Down syndrome (Project/Area Number: 20K10204 )
Pathophysiology of periodontitis progression by IL-1 and geriatric impaired testosterone in diabetic patients (Project/Area Number: 19K10131 )
Relationship between periodontal pathogen and estimated glomerular filtration rate (eGFR) in patients with chronic kidney disease (Project/Area Number: 19K10111 )
Elucidation of the roles in the dental pulp of the innate immune receptor, Mincle, which recognizes dead cells by bacterial infection (Project/Area Number: 18K09577 )
Relationship of periodontal infection and inflammatory cytokine to the incidence of infective endocarditis (Project/Area Number: 26463135 )
Study on the risk of infective endocarditis accompanied with the progression of periodontitis (Project/Area Number: 23593063 )
歯乳頭細胞の分化発現に果たす骨芽細胞特異的転写因子Cbfa1の役割 (Project/Area Number: 14771055 )
ストレスが歯周病の危険因子であるかどうかの直接的証明 (Project/Area Number: 13877358 )
歯髄組織における骨芽細胞特異的転写因子Cbfa1の発現と調節 (Project/Area Number: 12771144 )
象牙質形成における歯髄組織中の基質蛋白および遺伝子発現の組織学的研究 (Project/Area Number: 10771048 )
Search by Researcher Number (10291494)

Assistant Professor : Ninomiya, Masami

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Grants-in-Aid for Scientific Research (KAKEN Grants Database @ NII.ac.jp)