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Research Activity

Field of Study

Dentistry

Subject of Study

Book / Paper

Book:

1. Tadashi Nakanishi and Takashi Matsuo :
2. 感染根管における細菌感染の実態,
株式会社ヒョーロン・パブリッシャーズ, Jun. 2019.
2. Takashi Matsuo and Tadashi Nakanishi :
第17章 高齢者・有病者の歯内治療,
医歯薬出版株式会社, Sep. 2018.
3. Takashi Matsuo and Tadashi Nakanishi :
第1章 歯と歯根周囲の組織学,
永末書店, Jan. 2018.
4. Tadashi Nakanishi :
新・歯科衛生士教育マニュアル 保存修復 5 歯髄の保護法,
Quintessence Publishing CO.,Ltd., 東京, Sep. 2012.
5. Tadashi Nakanishi, Kanako Takahashi, Kazumi Ozaki, Hideaki Nakae and Takashi Matsuo :
Proceedings of the International Conference on Dentin/Pulp Complex 2001, --- An Immunohistologic Study on the Localization of Selected Bacteria and Chemokines in Human Deep-Carious Teeth ---,
Quintessence Publishing CO.,Ltd., Tokyo, Jun. 2002.

Academic Paper (Judged Full Paper):

1. Hitomi Kuramoto, Kouji Hirao, Hiromichi Yumoto, Yuki Hosokawa, Tadashi Nakanishi, Daisuke Takegawa, Ayako Washio, Chiaki Kitamura and Takashi Matsuo :
Caffeic acid phenethyl ester (CAPE) induces VEGF expression and production in rat odontoblastic cells,
BioMed Research International, Vol.Article ID 5390720, 2019.
(DOI: 10.1155/2019/5390720)
2. Kouji Hirao, Hiromichi Yumoto, Yuki Hosokawa, Hitomi Kuramoto, 鷲尾 絢子, Tadashi Nakanishi, Daisuke Takegawa, 北村 知昭 and Takashi Matsuo :
ラット象牙芽細胞様細胞 (KN-3) におけるカテキンの抗炎症作用,
The Japanese Journal of Conservative Dentistry, Vol.60, No.5, 235-244, 2017.
3. Yuki Hosokawa, Kouji Hirao, Hiromichi Yumoto, Ayako Washio, Tadashi Nakanishi, Daisuke Takegawa, Chiaki Kitamura and Takashi Matsuo :
Functional roles of NOD1 in odontoblasts on dental pulp innate immunity,
BioMed Research International, Vol.2016, 9325436, 2016.
(Tokushima University Institutional Repository: 112386,   DOI: 10.1155/2016/9325436,   PubMed: 27747243,   Elsevier: Scopus)
4. Tadashi Nakanishi, Kayo Mukai, Yoshitaka Hosokawa, Daisuke Takegawa and Takashi Matsuo :
Catechins inhibit vascular endothelial growth factor production and cyclooxygenase-2 expression in human dental pulp cells,
International Endodontic Journal, Vol.48, No.3, 277-282, 2015.
(DOI: 10.1111/iej.12312,   PubMed: 24847951)
5. Daisuke Takegawa, Tadashi Nakanishi, Kouji Hirao, Hiromichi Yumoto, Kanako Takahashi and Takashi Matsuo :
Modulatory roles of interferon-γ through indoleamine 2, 3-dioxygenase induction in innate immune response of dental pulp cells.,
Journal of Endodontics, Vol.40, No.9, 1382-1387, 2014.
(DOI: 10.1016/j.joen.2014.03.018,   PubMed: 25146019,   Elsevier: Scopus)
6. Tadashi Nakanishi, Daisuke Takegawa, Kouji Hirao, Kanako Takahashi, Hiromichi Yumoto and Takashi Matsuo :
Roles of dental pulp fibroblasts in the recognition of bacterium-related factors and subsequent development of pulpitis,
Japanese Dental Science Review, Vol.47, No.2, 161-166, 2011.
(DOI: 10.1016/j.jdsr.2011.02.001,   CiNii: 10029548123)
7. Yoshitaka Hosokawa, Ikuko Hosokawa, Satoru Shindo, Kazumi Ozaki, Tadashi Nakanishi, Hideaki Nakae and Takashi Matsuo :
Black tea polyphenol inhibits CXCL10 production in oncostatin M-stimulated human gingival fibroblasts.,
International Immunopharmacology, Vol.11, No.6, 670-674, 2011.
(DOI: 10.1016/j.intimp.2011.01.009,   PubMed: 21255696)
8. Gilson C. N. Franco, Mikihito Kajiya, Tadashi Nakanishi, Kouji Ohta, Pedro L. Rosalen, Francisco C. Groppo, Cory W. O. Ernst, Janie L. Boyesen, John D. Bartlett, Philip Stashenko, Martin A. Taubman and Toshihisa Kawai :
Inhibition of matrix metalloproteinase-9 activity by doxycycline ameliorates RANK ligand-induced osteoclast differentiation in vitro and in vivo.,
Experimental Cell Research, Vol.317, No.10, 1454-1464, 2011.
(DOI: 10.1016/j.yexcr.2011.03.014,   PubMed: 21420951)
9. Yoshitaka Hosokawa, Ikuko Hosokawa, Kazumi Ozaki, Tadashi Nakanishi, Hideaki Nakae and Takashi Matsuo :
Tea polyphenols inhibit IL-6 production in tumor necrosis factor superfamily 14-stimulated human gingival fibroblasts.,
Molecular Nutrition & Food Research, Vol.54 Suppl 2, S151-8, 2010.
(DOI: 10.1002/mnfr.200900549,   PubMed: 20461739)
10. Yoshitaka Hosokawa, Ikuko Hosokawa, Kazumi Ozaki, Tadashi Nakanishi, Hideaki Nakae and Takashi Matsuo :
Catechins inhibit CXCL10 production from oncostatin M-stimulated human gingival fibroblasts,
The Journal of Nutritional Biochemistry, Vol.21, No.7, 659-664, 2010.
(DOI: 10.1016/j.jnutbio.2009.04.005,   PubMed: 19616927)
11. Kouji Hirao, Hiromichi Yumoto, Tadashi Nakanishi, Kayo Mukai, Kanako Takahashi, Daisuke Takegawa and Takashi Matsuo :
Tea catechins reduce inflammatory reactions via mitogen-activated protein kinase pathways in toll-like receptor 2 ligand-stimulated dental pulp cells.,
Life Sciences, Vol.86, No.17-18, 654-660, 2010.
(DOI: 10.1016/j.lfs.2010.02.017,   PubMed: 20176036)
12. Tadashi Nakanishi, Kayo Mukai, Hiromichi Yumoto, Kouji Hirao, Yoshitaka Hosokawa and Takashi Matsuo :
Anti-inflammatory effect of catechin on cultured dental pulp cells affected by bacteria-derived factors,
European Journal of Oral Sciences, Vol.118, No.2, 145-150, 2010.
(DOI: 10.1111/j.1600-0722.2010.00714.x,   PubMed: 20487003)
13. Yoshitaka Hosokawa, Ikuko Hosokawa, Kazumi Ozaki, Tadashi Nakanishi, Hideaki Nakae and Takashi Matsuo :
Catechins Inhibit CCL20 Production in IL-17A-stimulated Human Gingival Fibroblasts,
Cellular Physiology and Biochemistry, Vol.24, No.5-6, 391-396, 2009.
(DOI: 10.1159/000257431,   PubMed: 19910679)
14. Kouji Hirao, Hiromichi Yumoto, Kanako Takahashi, Kayo Mukai, Tadashi Nakanishi and Takashi Matsuo :
Roles of TLR2, TLR4, NOD2, and NOD1 in pulp fibroblasts.,
Journal of Dental Research, Vol.88, No.8, 762-767, 2009.
(DOI: 10.1177/0022034509341779,   PubMed: 19734466)
15. Kanako Takahashi, Tadashi Nakanishi, Hiromichi Yumoto, Tomohiko Adachi and Takashi Matsuo :
CCL20 production is induced in human dental pulp upon stimulation by Streptococcus mutans and pro-inflammatory cytokines,
Oral Microbiology and Immunology, Vol.23, No.4, 320-327, 2008.
(DOI: 10.1111/j.1399-302X.2008.00431.x,   PubMed: 18582332)
16. Tomohiko Adachi, Tadashi Nakanishi, Hiromichi Yumoto, Kouji Hirao, Kanako Takahashi, Kayo Mukai, Hideaki Nakae and Takashi Matsuo :
Caries-related bacteria and cytokines induce CXCL10 in dental pulp.,
Journal of Dental Research, Vol.86, No.12, 1217-1222, 2007.
(DOI: 10.1177/154405910708601215,   PubMed: 18037659)
17. Cory W. Ernst, Jang Eun Lee, Tadashi Nakanishi, Nadeem Y. Karimbux, Taia M. Rezende, Philip Stashenko, Makoto Seki, Martin A Taubman and Toshihisa Kawai :
Diminished forkhead box P3/CD25 double-positive T regulatory cells are associated with the increased nuclear factor-kB ligand (RANKL(+)) T cells in bone resorption lesion of periodontal disease,
Clinical and Experimental Immunology, Vol.148, No.2, 271-280, 2007.
(DOI: 10.1111/j.1365-2249.2006.03318.x,   PubMed: 17355249)
18. Yoshitaka Hosokawa, Tadashi Nakanishi, Daisuke Yamaguchi, Hideaki Nakae and Takashi Matsuo :
Expression of fractalkine (CX3CL1) and its receptor, CX3CR1, in periodontal diseased tissue,
Clinical and Experimental Immunology, Vol.139, No.3, 506-512, 2005.
(DOI: 10.1111/j.1365-2249.2005.02675.x,   PubMed: 15730397)
19. Tadashi Nakanishi, Kanako Takahashi, Yoshitaka Hosokawa, Tomohiko Adachi, Hideaki Nakae and Takashi Matsuo :
Expression of macrophage inflammatory protein 3alpha in human inflamed dental pulp tissue,
Journal of Endodontics, Vol.31, No.2, 84-87, 2005.
(DOI: 10.1097/01.don.0000143414.22112.57,   PubMed: 15671814)
20. Takashi Matsuo, Toshiyuki Shirakami, Kazumi Ozaki, Tadashi Nakanishi, Hiromichi Yumoto and Shigeyuki Ebisu :
An immunohistological study of the localization of bacteria invading root pulpal walls of teeth with periapical lesions,
Journal of Endodontics, Vol.29, No.3, 194-200, 2003.
(DOI: 10.1097/00004770-200303000-00008,   PubMed: 12669880)
21. Yoshitaka Hosokawa, Tadashi Nakanishi, Daisuke Yamaguchi, Kanako Takahashi, Hiromichi Yumoto, Kazumi Ozaki and Takashi Matsuo :
Macrophage Inflammatory Protein 3α-CC chemokine receptor 6 interactions play an important role in CD4+ T-cell accumulation in periodontal diseased tissue.,
Clinical and Experimental Immunology, Vol.128, No.3, 548-554, 2002.
(DOI: 10.1046/j.1365-2249.2002.01865.x,   PubMed: 12067311)
22. Tadashi Nakanishi, Hirotoshi Shimizu, Yoshitaka Hosokawa and Takashi Matsuo :
An immunohistological study on cyclooxygenase-2 in human dental pulp.,
Journal of Endodontics, Vol.27, No.6, 385-388, 2001.
(DOI: 10.1097/00004770-200106000-00003,   PubMed: 11487130)
23. Takashi Matsuo, Tadashi Nakanishi, Hirotoshi Shimizu and Shigeyuki Ebisu :
A clinical study of direct pulp capping applied to carious-exposed pulps,
Journal of Endodontics, Vol.22, No.10, 551-556, 1996.
24. Takashi Matsuo, Tadashi Nakanishi and Shigeyuki Ebisu :
Immunoglobulins in periapical exudates of infected root canals: correlations with the clinical findings of the involved teeth,
Endodontics & dental traumatology, Vol.11, No.2, 95-99, 1995.
25. Tadashi Nakanishi, Takashi Matsuo and Shigeyuki Ebisu :
Quantitative analysis of immunoglobulins and inflammatory factors in human pulpal blood from exposed pulps,
Journal of Endodontics, Vol.21, No.3, 131-136, 1995.
26. Takashi Matsuo, Shigeyuki Ebisu, Tadashi Nakanishi, Kouki Yonemura, Yasushi Harada and Hiroshi Okada :
Interleukin-1 alpha and interleukin-1 beta periapical exudates of infected root canals: correlations with the clinical findings of the involved teeth,
Journal of Endodontics, Vol.20, No.9, 432-435, 1994.
27. Tadashi Nakanishi, Takashi Matsuo, 多川 知里, 白神 俊之 and Shigeyuki Ebisu :
Diagnosis of Pulpitis Using Pulpal Blood, --- Establishment of the Method for Collection of Pulpal Blood ---,
The Japanese Journal of Conservative Dentistry, Vol.36, No.5, 1404-1409, 1993.
28. Masahiro Yoshiyama, Kazumi Ozaki, Yuichiro Noiri, Kenya Kataoka, Tadashi Nakanishi, Reiko Ogimoto, Hideaki Nakae, Takashi Matsuo and Shigeyuki Ebisu :
Treatment of Dentin Hypersensitivity-Effect of a Light-curing Resin Liner on Tubule Occlusion-,
The Japanese Journal of Conservative Dentistry, Vol.34, No.1, 76-81, 1991.
29. yuichiro Noiri, Kazumi Ozaki, Tadashi Nakanishi, Kenya Ktaoka, Ichiro Amano and Masahiro Yoshiyama :
Study on Adhesive Properties of Restorative Materials to Human Root Dentin, --- 1.Adhesive Properties of Resin Cement Used for Composite Resin Inlay Restoration to Human Coronal and Root Debtin ---,
The Japanese Journal of Conservative Dentistry, Vol.33, No.3, 639-647, 1990.

Academic Paper (Unrefereed Paper):

1. Takashi Matsuo, Tadashi Nakanishi, Hiromichi Yumoto, Kouji Hirao, Chihiro Shinohara and Toshihiko Tominaga :
Conception of Infected Root Canal Treatment,
Journal of Oral Health and Biosciences, Vol.28, No.2, 87-92, 2016.
(Tokushima University Institutional Repository: 109873,   CiNii: 120005823528)

Review, Commentary:

1. Takashi Matsuo and Tadashi Nakanishi :
深在性う蝕への対応と歯髄の免疫応答,
The Japanese Journal of Conservative Dentistry, Vol.62, No.1, 1-7, Feb. 2019.
(DOI: 10.11471/shikahozon.62.1)
2. Hiromichi Yumoto, Kouji Hirao, Yuki Hosokawa, Hitomi Kuramoto, Daisuke Takegawa, Tadashi Nakanishi and Takashi Matsuo :
The Roles of Odontoblasts in Dental Pulp Innate Immunity,
Japanese Dental Science Review, Vol.54, No.3, 105-117, Aug. 2018.
(Tokushima University Institutional Repository: 112960,   DOI: 10.1016/j.jdsr.2018.03.001,   PubMed: 30128058,   Elsevier: Scopus)
3. Tadashi Nakanishi and Takashi Matsuo :
感染根管における細菌感染の実態,
The Nippon Dental Review, Vol.77, No.11, 45-58, Nov. 2017.
4. Takashi Matsuo and Tadashi Nakanishi :
歯髄炎の病態形成における細菌侵襲と歯髄の反応性,
The Nippon Dental Review, Vol.73, No.6, 9-11, Jun. 2013.
(CiNii: 40019691366)
5. Takashi Matsuo, Kazumi Ozaki, Tadashi Nakanishi, Hiromichi Yumoto, Kanako Takahashi, Kouji Hirao and Daisuke Takegawa :
Pulp pathosis and its diagnosis,
日本歯内療法学会雑誌, Vol.34, No.2, 67-76, May 2013.
(CiNii: 10031183916)
6. Tadashi Nakanishi :
歯髄炎の病態形成における細菌侵襲と歯髄の反応性,
The Japanese Journal of Conservative Dentistry, Vol.53, No.5, 489-491, Oct. 2010.
7. Takashi Matsuo and Tadashi Nakanishi :
Pharmacologic Control of Dental Pain,
the Quintessence, Vol.22, No.6, 147-161, Jun. 2003.
8. Yoshitaka Hosokawa, Tadashi Nakanishi and Takashi Matsuo :
Expresion of Chemokines in periodontitis,
Clinical Immunology, Vol.38, No.2, 151-156, Feb. 2002.
9. Tadashi Nakanishi, Kanako Takahashi, Yoshitaka Hosokawa, Kazumi Ozaki and Takashi Matsuo :
Bacterial irritation and pulpal response in pulpitis,
Shikoku Dental Research, Vol.14, No.2, 255-263, 2002.
10. Takashi Matsuo, Tadashi Nakanishi and Keiko Fujinaka :
Pathology of Apical Periodontitis Refractory to endod,
現代の根管治療の診断科学, 91-97, 1999.

Proceeding of International Conference:

1. Yuki Hosokawa, Hiromichi Yumoto, Kouji Hirao, Hitomi Kuramoto, Tadashi Nakanishi, Daisuke Takegawa and Takashi Matsuo :
Anti-inflammatory effects of polyphenols on rat odontoblastic cells,
95th General Session & Exhibition of the International Association for Dental Research (San Francisco), Mar. 2017.
2. Daisuke Takegawa, Tadashi Nakanishi, Kouji Hirao, Hiromichi Yumoto, Yuki Hosokawa and Takashi Matsuo :
Interferon-gamma modulates the innate immune response in odontoblast-like cells,
95th General session and exhibition of the IADR, Mar. 2017.
3. Tadashi Nakanishi, Daisuke Takegawa, Kouji Hirao, Hiromichi Yumoto, Yuki Hosokawa and Takashi Matsuo :
Effect of interleukin-17A on CCL20 production from odontoblast-like cells,
95th General session and exhibition of the IADR, Mar. 2017.
4. Tadashi Nakanishi, Daisuke Takegawa, Hiromichi Yumoto, Kouji Hirao and Takashi Matsuo :
Interleukin-17 Regulates Inflammatory Mediator Expression in IL-1beta-stimulated Dental Pulp Cells,
93th General Session & Exhibition of the International Association for Dental Research, Boston (USA), Mar. 2015.
5. Tadashi Nakanishi, Daisuke Takegawa, Kouji Hirao, Hiromichi Yumoto, Kanako Takahashi and Takashi Matsuo :
Prostaglandin F2a Regulates Cytokine Expression in Dental Pulp Cells,
91th General Session & Exhibition of the IADR, Seattle, USA, Mar. 2013.
6. Daisuke Takegawa, Tadashi Nakanishi, Kouji Hirao, Hiromichi Yumoto, Kanako Takahashi and Takashi Matsuo :
Interferon-g modulates the innate immune response of dental pulp cells,
91th General Session & Exhibition of the IADR, Seattle, USA, Mar. 2013.
7. Tadashi Nakanishi, Kouji Hirao, Takegawa Daisuke, Hiromichi Yumoto, Kanako Takahashi and Takashi Matsuo :
Catechins suppress cyclooxygenase-2 expression in human dental pulp cells,
88th General Session and Exhibition of the IADR, Jul. 2010.
8. Takegawa Daisuke, Tadashi Nakanishi, Kouji Hirao, Hiromichi Yumoto, Kanako Takahashi and Takashi Matsuo :
Interferon-gamma enhances toll-like receptor ligand-induced cytokine production in pulpal cells,
88th General Session and Exhibition of the IADR, Jul. 2010.
9. Kayo Mukai, Tadashi Nakanishi, Hiromichi Yumoto, Kanako Takahashi, Kouji Hirao and Takashi Matsuo :
Effects of Catechins on Cytokine Production in Human Odontoblast-like Cells,
86th General Session and Exhibition of the International Association for Dental Research, Jul. 2008.
10. Kouji Hirao, Hiromichi Yumoto, Tadashi Nakanishi, Kanako Takahashi, Kayo Mukai, Miho Yoneda and Takashi Matsuo :
Functional Analysis of Pattern Recognition Receptor Expression in Pulpal Cells,
86th General Session and Exhibition of the International Association for Dental Research, Jul. 2008.
11. Kayo Mukai, Tadashi Nakanishi, Yoshitaka Hosokawa, Kanako Takahashi and Takashi Matsuo :
Inhibitory effects of catechins on inflammatory reactions in pulp fibroblasts,
84th General Session & Exhibition of the IADR, Brisbane, Jun. 2006.
12. Tadashi Nakanishi, Jean Eastcott, Martin A Taubman and Toshihisa Kawai :
Characteristics of regulatory dendritic cells induced by gingival epithelial cells,
35th Annual Meeting & Exhibition of the AADR, Orlando, Mar. 2006.
13. Tadashi Nakanishi, Jean Eastcott, Martin A Taubman and Toshihisa Kawai :
Induction of regulatory dendritic cells by gingival epithelial cells,
83rd General session of IADR (International Association for Dental Research), Baltimore, Mar. 2005.
14. Tadashi Nakanishi, Tomohiko Adachi, Kanako Takahashi and Takashi Matsuo :
Expression of interferon-gamma -inducible protein 10/CXCL10 in inflamed dental pulp,
82th General Session of the IADR(INternational Association of Dental Research), Honolulu, Mar. 2004.
15. Kanako Takahashi, Tadashi Nakanishi, Tomohiko Adachi, Natsuko Ida, Hideaki Nakae and Takashi Matsuo :
Effects of Streptococcus mutans on MIP-3 α production by macrophages,
82th General Session of the IADR(INternational Association of Dental Research), Honolulu, Mar. 2004.
16. Daisuke Yamaguchi, Tadashi Nakanishi, Kanako Takahashi, Hideaki Nakae and Takashi Matsuo :
Expression of macrophage inflammatory protein-3alpha/CCL20 in human gingival epithelial cells,
81th General Session of the IADR(INternational Association of Dental Research), エルサレム, Jun. 2003.
17. Yoshitaka Hosokawa, Tadashi Nakanishi, Daisuke Yamaguchi, Hiromichi Yumoto and Takashi Matsuo :
LARC-CCR6 Interactions play an important role in CD4+ T cell accumulation in periodontal diseased tissue,
80th General Session and Exhibition of the International Association for Dental Research, San Diego(USA), Mar. 2002.
18. Tadashi Nakanishi, Kanako Takahashi, Yoshitaka Hosokawa, Daisuke Yamaguchi, Chihiro Shinohara, Hiromichi Yumoto and Takashi Matsuo :
Expression of macrophage inflammatory protein-3 α in human pulpitis,
80th General SEssion ofthe IADR(International Association of Dental Research), San Diego(USA), Mar. 2002.
19. Tadashi Nakanishi, Kanako Takahashi, Kazumi Ozaki, Hideaki Nakae and Takashi Matsuo :
An immunohistological study on the localization of selected bacteria and chemokines in human deep-carious teeth,
The International Conference on Dentin/Pulp complexs, Chiba, Jul. 2001.
20. Hiromichi Yumoto, Daisuke Yamaguchi, Yoshitaka Hosokawa, Chihiro Shinohara, Tadashi Nakanishi, Hirotoshi Shimizu, Masayoshi Yamada, Hideaki Nakae and Takashi Matsuo :
Expression of IL-18 and IL-18 receptor in human periodontally diseased tissue,
Modern Periodontology New Directions in 21st Century-, Kanagawa(Japan), Jun. 2001.

Proceeding of Domestic Conference:

1. Hitomi Kuramoto, Kouji Hirao, Yuki Hosokawa, Daisuke Takegawa, Hiromichi Yumoto and Tadashi Nakanishi :
ラット象牙芽細胞(KN-3)におけるVEGFの石灰化誘導作用,
日本歯科保存学会 2019年度秋季学術大会(第151回) (福岡), Nov. 2019.
2. Daisuke Takegawa, Tadashi Nakanishi, Kouji Hirao, Hiromichi Yumoto, Yuki Hosokawa, 蔵本 瞳 and Takashi Matsuo :
Effects of interferon-γ on innate host responses in cultured odontoblast-like cells stimulated with NOD ligands,
第150回 日本歯科保存学会 2019年度 春季学術大会, Jun. 2019.
3. 蔵本 瞳, Hiromichi Yumoto, Kouji Hirao, Yuki Hosokawa, Tadashi Nakanishi, Daisuke Takegawa and Takashi Matsuo :
Caffeic Acid Phenetyl Ester (CAPE)の象牙芽細胞と骨芽細胞におけるVEGF産生誘導機序の解析,
第148回日本歯科保存学会春季学術大会, Jun. 2018.
4. 蔵本 瞳, Hiromichi Yumoto, Kouji Hirao, 細川 由樹, Tadashi Nakanishi, Daisuke Takegawa and Takashi Matsuo :
Caffeic Acid Phenethyl Ester (CAPE)のラット象牙芽細胞(KN-3)におけるVEGF産生に与える影響,
日本歯科保存学会2017年度春季学術大会(第146回), Jun. 2017.
5. Tadashi Nakanishi, Daisuke Takegawa, Kouji Hirao, Hiromichi Yumoto, 細川 由樹 and Takashi Matsuo :
Interleukin-17がラット象牙芽細胞様細胞(KN-3)のCCL20産生に及ぼす影響,
日本歯科保存学会 2015年度秋季学術大会(第143回), Nov. 2015.
6. 細川 由樹, Hiromichi Yumoto, Kouji Hirao, Tadashi Nakanishi, Daisuke Takegawa and Takashi Matsuo :
象牙芽細胞が有するMincleを介した視細胞認識機構とその歯髄炎症反応における役割,
日本歯科保存学会 2015年度秋季学術大会(第143回), Nov. 2015.
7. Kouji Hirao, Hiromichi Yumoto, 細川 由樹, Tadashi Nakanishi, Daisuke Takegawa and Takashi Matsuo :
ラット象牙芽細胞(KN-3)の自然免疫反応におけるシグナル伝達経路の解析,
日本歯科保存学会2015年度春季学術大会(第142回), Jun. 2015.
8. 細川 由樹, Hiromichi Yumoto, Kouji Hirao, Tadashi Nakanishi, Daisuke Takegawa and Takashi Matsuo :
ラット象牙芽細胞(KN-3)に対するカテキンとカフェイン酸の抗炎症作用,
日本歯科保存学会2015年度春季学術大会(第142回), Jun. 2015.
9. Takashi Matsuo, Tadashi Nakanishi, Hiromichi Yumoto, Chihiro Shinohara and Kouji Hirao :
感染根管治療の考え方,
四国歯学会(第46回例会), Mar. 2015.
10. Tadashi Nakanishi, Daisuke Takegawa, Kouji Hirao, Hiromichi Yumoto and Takashi Matsuo :
Interleukin-17がヒト歯髄線維芽細胞の炎症メディエーター発現に及ぼす影響,
日本歯科保存学会2014年度秋季学術大会(第141回), Oct. 2014.
11. Kouji Hirao, Hiromichi Yumoto, Tadashi Nakanishi, Chihiro Shinohara, Kanako Takahashi, Daisuke Takegawa, 細川 由樹 and Takashi Matsuo :
ラット象牙芽細胞様細胞(KN3)における細菌関連病原因子刺激に対する自然免疫反応の解析,
日本歯科保存学会2014年度春季学術大会(第140回), Jun. 2014.
12. Yoshitaka Hosokawa, Ikuko Hosokawa, Kazumi Ozaki, Tadashi Nakanishi, Hideaki Nakae and Takashi Matsuo :
The effect of catechin on CCL11 production from TNF-alpha -stimulated human gingival fibroblasts,
The Japanese Journal of Conservative Dentistry, Jun. 2012.
13. Tadashi Nakanishi, Daisuke Takegawa, Kouji Hirao, Hiromichi Yumoto, Kanako Takahashi and Takashi Matsuo :
prostaglandin F2aは歯髄細胞における炎症性メディエーター発現を調節する,
第136回日本歯科保存学会春季学術大会, Jun. 2012.
14. Yoshitaka Hosokawa, Ikuko Hosokawa, Kazumi Ozaki, Tadashi Nakanishi and Takashi Matsuo :
The effect of TWEAK on CCL20 production on IL-1beta-stimulated human gingival fibroblasts,
The Japanese Journal of Conservative Dentistry, Oct. 2011.
15. Yoshitaka Hosokawa, Ikuko Hosokawa, Kazumi Ozaki, Tadashi Nakanishi, Hideaki Nakae and Takashi Matsuo :
The effect of theaflavin on IL-6 production in TNFSF14-stimulated human gingival fibroblasts,
The Japanese Journal of Conservative Dentistry, Jun. 2011.
16. 武川 大輔, Tadashi Nakanishi, Kouji Hirao, Hiromichi Yumoto, Kanako Takahashi and Takashi Matsuo :
ヒト培養歯髄細胞の自然免疫応答に対するインターフェロンγの影響,
第134回日本歯科保存学会春季学術大会, Jun. 2011.
17. Shindo Satoru, Yoshitaka Hosokawa, Hosokawa Ikuko, Kazumi Ozaki, Tadashi Nakanishi, Hideaki Nakae and Takashi Matsuo :
Oncostatin Mが誘導するヒト歯肉線維芽細胞のCXCL10産生に及ぼす紅茶ポリフェノールの影響,
Journal of the Japanese Association of Periodontology, May 2011.
18. Tadashi Nakanishi, 武川 大輔, Kouji Hirao, Hiromichi Yumoto, Kanako Takahashi and Takashi Matsuo :
ヒト歯髄細胞におけるサイトカイン発現に対するProstaglandin F2alpha の影響,
日本歯科保存学会2010年度秋季学術大会(第133回), Oct. 2010.
19. Yoshitaka Hosokawa, Hosokawa Ikuko, Kazumi Ozaki, Tadashi Nakanishi, Hideaki Nakae and Takashi Matsuo :
The effect of catechin on IL-6 production from TNFSF14-stimulated human gingival fibroblasts,
The Japanese Journal of Conservative Dentistry, Oct. 2010.
20. Hashimoto Reina, Yoshitaka Hosokawa, Hosokawa Ikuko, Kazumi Ozaki, Tadashi Nakanishi, Hideaki Nakae and Takashi Matsuo :
IL-1betaが誘導するヒト歯肉線維芽細胞のCXCL10産生に及ぼす緑茶カテキンの影響,
Journal of the Japanese Association of Periodontology, Sep. 2010.
21. Kouji Hirao, Hiromichi Yumoto, Kayo Mukai, Kanako Takahashi, Tadashi Nakanishi and Takashi Matsuo :
カテキンは細菌やその構成成分に対する培養歯髄細胞の反応を調節する,
第127回日本歯科保存学会秋季学術大会, Nov. 2007.
22. Hiromichi Yumoto, Kouji Hirao, Kanako Takahashi, Kayo Mukai, Tadashi Nakanishi and Takashi Matsuo :
培養歯髄細胞におけるPattern Recognition Receptor (PRR)を介した接着分子の発現,
第127回日本歯科保存学会秋季学術大会, Nov. 2007.
23. Kayo Mukai, Tadashi Nakanishi, Yoshitaka Hosokawa, Kanako Takahashi and Takashi Matsuo :
カテキンが歯髄由来線維芽細胞の炎症性サイトカインおよび接着分子の発現誘導に与える影響,
第27回日本歯内療法学会学術大会, Jul. 2006.
24. Kayo Mukai, Tadashi Nakanishi, Yoshitaka Hosokawa, Kanako Takahashi, 足立 智彦 and Takashi Matsuo :
カテキンが歯髄由来線維芽細胞の炎症性サイトカインおよび接着分子の発現誘導に与える影響,
第124回日本歯科保存学会春季学術大会, May 2006.
25. 足立 智彦, Kouji Hirao, Hiromichi Yumoto, Kanako Takahashi, 向井 佳代, Tadashi Nakanishi, Hideaki Nakae and Takashi Matsuo :
歯髄組織および細菌刺激THP-1細胞におけるCXCR3 ligands(特にIP-10)の発現解析,
第123回秋季日本歯科保存会, Nov. 2005.
26. 向井 佳代, Tadashi Nakanishi, Yoshitaka Hosokawa, Kanako Takahashi, 足立 智彦 and Takashi Matsuo :
Toll-like receptor リガンドによる歯髄由来繊維芽細胞のIL-8, VEGF, 接着分子発現誘導,
第122回春季日本歯科保存学会, Jun. 2005.
27. 足立 智彦, Tadashi Nakanishi, Kanako Takahashi and Takashi Matsuo :
歯髄線維芽細胞における細菌由来因子によるIP-10発現,
第122回春季日本歯科保存学会, Jun. 2005.
28. Kayo Mukai, Tadashi Nakanishi, Yoshitaka Hosokawa, Kanako Takahashi, 足立 智彦 and Takashi Matsuo :
Toll-like receptor リガンドによる歯髄線維芽細胞のIL-8,VEGF,接着分子の発現誘導,
第122回日本歯科保存学会春季学術大会, Jun. 2005.
29. 足立 智彦, Tadashi Nakanishi, Kanako Takahashi and Takashi Matsuo :
歯髄炎の病態形成におけるIP-10の役割,
第33回日本免疫学会総会, Dec. 2003.
30. Kanako Takahashi, Tadashi Nakanishi, 足立 智彦, 位田 夏子, Hideaki Nakae and Takashi Matsuo :
THP-1細胞からのサイトカイン産生におけるStrepptococcus mutansの影響について,
第33回日本免疫学会総会, Dec. 2003.
31. 足立 智彦, Tadashi Nakanishi, Kanako Takahashi, 向井 佳代 and Takashi Matsuo :
歯髄炎におけるCXCL10の発現に関する研究,
第119回秋季日本歯科保存学会, Nov. 2003.
32. Kanako Takahashi, Tadashi Nakanishi, Daisuke Yamaguchi, Yoshitaka Hosokawa, Hiromichi Yumoto, Kazumi Ozaki, Hideaki Nakae and Takashi Matsuo :
歯髄炎の病態形成におけるLARCおよびCCR6の役割,
第32回 日本免疫学会, Dec. 2002.
33. Chihiro Shinohara, Tadashi Nakanishi, 末延 慎司, Kazumi Ozaki and Takashi Matsuo :
抜歯に至った難治性根尖性歯周炎の1症例,
第116回 日本歯科保存学会春季学会, Vol.45, 114, May 2002.
34. Daisuke Yamaguchi, Yoshitaka Hosokawa, Chihiro Shinohara, Hiromichi Yumoto, Tadashi Nakanishi, Hideaki Nakae and Takashi Matsuo :
歯周炎病変局所におけるFractalkineおよびCX3CR1の発現,
第45回春季日本歯周病学会, Apr. 2002.
35. Yoshitaka Hosokawa, Tadashi Nakanishi, Daisuke Yamaguchi, Hirotoshi Shimizu, Kazumi Ozaki, Hideaki Nakae and Takashi Matsuo :
歯周炎病変局所におけるLARCおよびCCR6の発現,
第31回 日本免疫学会, Dec. 2001.
36. Daisuke Yamaguchi, Yoshitaka Hosokawa, Hiromichi Yumoto, Tadashi Nakanishi, Hideaki Nakae and Takashi Matsuo :
歯周炎病変局所におけるIL-18とその機能に関連する分子の発現について,
第31回日本免疫学会学術集会, Dec. 2001.
37. Kanako Takahashi, Tadashi Nakanishi, Yoshitaka Hosokawa, Chihiro Shinohara, Hiromichi Yumoto, Kazumi Ozaki and Takashi Matsuo :
炎症歯髄におけるLARCおよびCCR6の発現,
第115回 秋季日本歯科保存学会, Nov. 2001.
38. Yoshitaka Hosokawa, Tadashi Nakanishi, Daisuke Yamaguchi, Hirotoshi Shimizu, Hiromichi Yumoto, Kazumi Ozaki and Takashi Matsuo :
歯周炎病変局所におけるLARCおよびCCR6の発現,
第44回 秋季日本歯周病学会学術大会, Oct. 2001.
39. Takashi Matsuo, Tadashi Nakanishi, Kanako Takahashi, Kazumi Ozaki and Hideaki Nakae :
歯髄炎の不可逆性化に関する臨床的および病理学的考察,
第14回 「歯内療法の集い」, May 2001.
40. Daisuke Yamaguchi, Yoshitaka Hosokawa, Hirotoshi Shimizu, Chihiro Shinohara, Hiromichi Yumoto, Tadashi Nakanishi and Takashi Matsuo :
歯周炎の病変局所におけるIL-18およびIL-18レセプターの発現,
第44回春季日本歯周病学会学術大会, Apr. 2001.
41. Tadashi Nakanishi, Nozomi Matsuoka, Kanako Takahashi, Kazumi Ozaki, Hideaki Nakae and Takashi Matsuo :
深在う蝕における侵入細菌の局所と歯髄反応,
第113回 秋季日本歯科保存学会, Nov. 2000.
42. Yoshitaka Hosokawa, 山口 大輔, 清水 洋利, Tadashi Nakanishi, Kazumi Ozaki, Hideaki Nakae and Takashi Matsuo :
歯周炎の病巣局所におけるケモカインおよびケモカイン受容体の発現,
第30回 日本免疫学会総会, Nov. 2000.
43. Hirotoshi Shimizu, Yoshitaka Hosokawa, Daisuke Yamaguchi, Tadashi Nakanishi, Kazumi Ozaki, Hideaki Nakae and Takashi Matsuo :
歯周炎の病巣局所におけるリンパ球浸潤に対するケモカインの関与,
第29回 日本免疫学会総会, Dec. 1999.
44. Kazumi Ozaki, Tadashi Nakanishi, Keiko Fujinaka and Takashi Matsuo :
歯根部象牙質齲蝕誘発モデルの細菌学ならびに形態学的検索,
第110回 日本歯科保存学会春季学会, May 1999.
45. Hirotoshi Shimizu, Yoshitaka Hosokawa, Tadashi Nakanishi, Kazumi Ozaki and Hideaki Nakae :
歯周炎の病巣局所におけるVCAM-1,VLA-4を介する接着系の解析,
第28回 日本免疫学会, Dec. 1998.
46. Tadashi Nakanishi, Hirotoshi Shimizu, Kazumi Ozaki, Hideaki Nakae and Takashi Matsuo :
多形核白血球の集積化による歯髄組織破壊機構の解析,
第105回 日本歯科保存学会春秋季学会, Nov. 1996.
47. Takashi Matsuo, Tadashi Nakanishi, 片岡 健哉, Kazumi Ozaki, 野杁 由一郎, 大木元 玲子, Hideaki Nakae, 吉山 昌宏 and 恵比須 繁之 :
覆髄法の適応範囲の拡大に関する臨床的検討,
第14回 四国歯学会, Jul. 1991.
48. Masahiro Yoshiyama, Kazumi Ozaki, Yuichiro Noiri, Kenya Kataoka, Tadashi Nakanishi, Reiko Ogimoto, Hideaki Nakae, Takashi Matsuo and Shigeyuki Ebisu :
Treatment of Dentin Hypersensitivity, --- Effect of a Light-curing Resin Liner on Tubule Occlusion ---,
第93回 日本歯科保存学会秋季学会, Sep. 1990.
49. Kazumi Ozaki, 野杁 由一郎, Tadashi Nakanishi, 片岡 健哉 and 吉山 昌宏 :
コンポジットレジンの歯根部象牙質に対する接着性,
第92回 日本歯科保存学会春季学会, Jun. 1990.

Grants-in-Aid for Scientific Research (KAKEN Grants Database @ NII.ac.jp)

  • 柑橘類果皮含有生理活性物質を歯周炎治療に用いるための基礎的研究 (Project/Area Number: 19K10151 )
  • 香辛料含有成分を歯周炎治療に用いるための基礎的研究-ローズマリーに着目して- (Project/Area Number: 18K09600 )
  • 初期の歯髄炎における象牙芽細胞の石灰化と生体防御機構の解明 (Project/Area Number: 17K11709 )
  • Development of a new approach to the treatments in conservative dentistry based on a concept for home or visit care. (Project/Area Number: 17K11708 )
  • 歯周炎病変局所における炎症性骨吸収に関与する白血球浸潤機構の解析 (Project/Area Number: 16K11834 )
  • role of melatonin in periodontal disease (Project/Area Number: 15K11392 )
  • Development of novel dental pulp preservation and calcification therapies by analyzing epigenetics and post-transcriptional regulation mechanism (Project/Area Number: 15K11117 )
  • The analysis of odontoblastic mechanism via innate immune system (Project/Area Number: 15K11116 )
  • Analysis of mechanism for pro-inflammatory and anti-inflammatory balance and role of Th17 cells in pulpitis (Project/Area Number: 15K11115 )
  • Application of electromagnetic wave irradiation to deep caries lesion. (Project/Area Number: 26462885 )
  • Analysis of Th17 cells migration and activation in periodontally diseased tissues (Project/Area Number: 25463219 )
  • Development of extracellular DNA-protein complex-targeting novel treatments and prevention for oral biofilm-related infectious diseases (Project/Area Number: 24592872 )
  • Analysis of a balance between pro-inflammatory and anti-inflammatory pulpal responses in the pathogenesis of pulpitis (Project/Area Number: 24592871 )
  • Development of a new comprehensive treatment for dental caries based on minimum intervention dentistry (Project/Area Number: 23390435 )
  • Endodontic therapeutic application of electro-magnetic wave irradiation for refractory periapical periodontitis and periapical biofilm (Project/Area Number: 21592423 )
  • Study on a therapeutic application of tea catechins to vital pulp treatment. (Project/Area Number: 20592228 )
  • Analysis of bacterial invasive lesion of refractory periapical periodontitis cases by genetic engineering technique (Project/Area Number: 18592092 )
  • Analysis of gingival epithelial cells and fibroblast using three-dimensional culture system mimic to periodontal pockets (Project/Area Number: 15592189 )
  • Study on the role of chemokines in the infiltration of inflammatory cells in dental pulp tissue destruction (Project/Area Number: 13672001 )
  • Analysis of the relationship between the invasion of dental caries-associated bacteria and the host response of dental pulp in human carious teeth with pulp exposure (Project/Area Number: 11671897 )
  • Bacterial Invasion of Infected Canals and Root Dentin of Human Teeth and Analysis of the Host-parasite Interaction at the Apex. - Elucidation of Pathogenesis of Refractory Cases-. (Project/Area Number: 10470406 )
  • 歯髄組織破壊における多形核白血球浸潤の細胞傷害性に関する研究 (Project/Area Number: 08771701 )
  • ヒト歯周炎における炎症浸潤細胞の接着機構の研究 (Project/Area Number: 08672193 )
  • 多形核白血球の集積化による歯髄組織破壊機構の解析 (Project/Area Number: 07771765 )
  • 歯髄血液を用いた不可逆性歯髄炎の診断に関する研究 (Project/Area Number: 06771719 )
  • 歯周組織破壊の進行過程における免疫担当細胞の動態 (Project/Area Number: 06671916 )
  • 歯髄炎の非可逆性化に関与する炎症機構の解析 (Project/Area Number: 04671162 )
  • Search by Researcher Number (00217770)