Takaharu Goto, Yukako Masutomi and Tetsuo Ichikawa : Distribution of main occluding area and associated factors in adolescents, Journal of Oral Science, Vol.66, No.4, 237-240, 2024.
Takaharu Goto, Shinji Fujiwara, Tomoya koda, Takashi Matsuda, Mio Kitamura, Yasuhiko Shirayama and Tetsuo Ichikawa : Biopsychosocial consideration of Ikigai in older adults in Japan through a cross-sectional study., Geriatrics, Vol.9, No.3, 78, 2024.
(Summary)
-a Japanese concept that includes elements such as life's purpose and meaning-has been reported to be associated with various systemic health conditions, such as the risk of developing physical dysfunction or death in older adults. However, there are no reports that comprehensively examine the psychological and social aspects of . We attempted to clarify the characteristics of by examining it from a biopsychosocial model using physical, psychological, and social perspectives through a cross-sectional study on sarcopenia, frailty and healthy life expectancy in a hilly and mountainous area of Japan. Koyadaira in Mima City, which is located in a hilly and mountainous region on Shikoku Island in Japan, was targeted. This cross-sectional study included 105 outpatients aged 65 and over, with an average age of 79.02 ± 6.91 years. (self-rating score on a scale of 0 (no ) to 5 (the highest )) participants' level of physical activity (the Physical Activity Scale for the Elderly, PASE), degree of depression (the Geriatric Depression-15 Scale, GDS-15), cognitive function (the Mini-Mental State Examination, MMSE) and social isolation (the abbreviated Lubben Social Network Scale, LSNS-6) was assessed. Significant positive correlations were found between PASE and MMSE. The LSNS-6 significantly correlated with the MMSE and GDS-15. In a path model, out of four paths from PASE, GDS-15, MMSE, and LSNS-6 to , the path from the GDS-15 alone was significant (correlation coefficient -0.271, < 0.01). The adaptability of this model was good. This study indicates that depressive status has a large impact on , along with physical, cognitive, and social conditions; thus, it is appropriate to consider that an affective psychological status, such as depressive symptoms, is a fundamental condition for having .
Adityakrisna Putra Yoshi Wigianto, Megumi Watanabe, Yuki Iwawaki, Takaharu Goto, Tamaki Otsuki and Tetsuo Ichikawa : Antimicrobial Efficacy of a Portable UV-C-Based Coating Activation Device against Candida albicans Biofilm and SARS-CoV-2 as an Additional Feature: An In Vitro Study., Hygiene, Vol.4, No.1, 93-102, 2024.
Yukako Masutomi, Takaharu Goto and Tetsuo Ichikawa : Mouth breathing reduces oral function in adolescence, Scientific Reports, Vol.14, No.1, 3810, 2024.
(Summary)
Although humans breathe naturally through the nostrils, mouth breathing in children has recently gathered attention. In this study, we hypothesized that tongue function and its related maxillofacial morphology would affect breathing in adolescence. To verify this hypothesis, we examined the association between breathing patterns, including mouth and nasal breathing; oral functions, including tongue motor function; and craniofacial morphology during adolescence, which has not been investigated till date. C3-H, which indicates the anteroposterior position of the hyoid bone in relation to the third cervical vertebra, was significantly smaller in mouth-breathers than in nasal-breathers. Lip-closing force, tongue pressure, and masticatory efficiency were lower in the order of nasal-breathers, oronasal-breathers, and mouth-breathers, and the values for mouth-breathers were significantly lower than those for nasal-breathers. Tongue pressure alone was identified as a significant independent variable, with an odds ratio of 1.063 (95% confidence interval, 1.006-1.123; p < 0.05). Our results indicate a relationship between mouth breathing and the lip-closing force, tongue pressure, and masticatory efficiency, as well as the significance of tongue pressure on mouth breathing in adolescents. The findings highlight the importance of clarifying the pathophysiology of mouth breathing and its underlying causes.
Takaharu Goto, Takahiro Kishimoto, Shinji Fujiwara, Yasuhiko Shirayama and Tetsuo Ichikawa : Social frailty as a predictor of all-cause mortality and functional disability: a systematic review and meta-analysis, Scientific Reports, Vol.14, No.1, 3410, 2024.
(Summary)
The association between social frailty and adverse health outcomes, especially mortality and functional disability, which are essential health outcomes, has not been systematically summarized or meta-analyzed. In this study, we conducted a systematic review and meta-analysis of the impact of social frailty on all-cause mortality and functional disability, while addressing the components of social frailty. In this study, social frailty was operationally defined in alignment with the previous literature, as follows: "a state of increased vulnerability to the interactive back-and-forth of the community, including general resources, social resources, social behaviors, and needs." Hazard ratios or odds ratios described in each selected literature were used as the meta-analytic results. Considering the impact of social frailty on all-cause mortality, the hazard ratio was 1.96 (95% CI 1.20-3.19), indicating a significant association between the two but high heterogeneity. The hazard and odds ratios for the impact of social frailty on functional disability were 1.43 (95% CI 1.20-1.69) and 2.06 (95% CI 1.55-2.74), respectively. A significant association was found between social frailty and functional disability; both hazard and odds ratios were found, and low heterogeneity between these articles was observed. These results highlight the importance of assessing social frailty using more standardized methods and examining its effects on various health outcomes.
(Keyword)
Humans / Aged / Frailty / Frail Elderly / Social Behavior / Odds Ratio / Proportional Hazards Models
Mio Kitamura, Yasuhiko Shirayama, Takaharu Goto, Tetsuo Ichikawa and Shinji Fujiwara : Association between working in small-scale cultivated land as a daily-life task and the physical and cognitive functions among elderly people in hilly and mountainous areas, Japanese Journal of Geriatrics, Vol.61, No.1, 54-60, 2024.
(Keyword)
Working in small-scale cultivated land / Older people / Daily-life task / Physical function / cognitive function
Hideki Suito, Keiko Fujimoto, Takaharu Goto, Kan Nagao, Hidehiko Hosoki and Tetsuo Ichikawa : Effective use of an extraoral vacuum in preventing the dispersal of particulate matter from metal dental materials., Journal of Occupational Health, Vol.65, No.1, e12412, 2023.
(Summary)
When dentists adjust prostheses at the dental chairside, particulate matter (PM) from the dental material is dispersed. Little is known about the effective use of an extraoral vacuum (EOV) in preventing PM dispersal. This study aimed to evaluate the effective use of an EOV in preventing the dispersal of metal PM in dental offices. The following experimental conditions were planned: the distance from the EOV to the metallic materials (50, 100, 150, and 200 mm), the horizontal angle between the long axis of the micromotor handpiece and EOV (0°, 45°, and 90°), and the operating time of the EOV (during grinding, during grinding and 1 min thereafter, during grinding and the preceding 1 min, 1 min before and after grinding, and during grinding). Carborundum and silicone points were used for grinding and PM dispersal. Diameters (0.3, 0.5, 1.0, and 3.0 μm) were measured using a laser particle counter. Depending on the instrument used to grind, there were undetectable PMs of different diameters (Carborundum point: 0.3 and 0.5 μm, Silicone point: 0.3 μm). PMNs were reduced as the distance from the EOV to metal materials decreased. Operating the EOV before grinding along the long axis of the micromotor handpiece was effective in reducing the PMNs. PMNs dispersed when grinding metals were effectively reduced by positioning the EOV closer to the grinding surface (within 150 mm) along the long axis of the micromotor handpiece and operating the EOV before grinding.
Kan Nagao, Keiko Fujimoto, Hideki Suito, Takaharu Goto, Yuichi Ishida, Megumi Watanabe and Tetsuo Ichikawa : Effect of Palatal Augmentation Prosthesis on Speech and Swallowing in Tongue Dysfunction:A Literature Review, Journal of Oral Health and Biosciences, Vol.35, No.2, 39-46, 2023.
(Summary)
Purpose: Palatal augmentation prosthesis (PAP) is used on patients with dysphagia and dysarthria. While several studies have evaluated the effects of PAP, evidence regarding the adaptation criteria, effects, and limitations of PAP are not well organized. This review aims to summarize its functions, limitations, and applications. Procedure: To investigate the adaptation criteria, effects, and limitations of PAP, we searched the English language literature published in PubMed from its inception through April 20, 2022. The leading search terms included ``palatal augmentation prosthesis.'' Main findings: The primary search used keywords that reflected 31 studies. Finally, nine cross-sectional studies and nine case reports were selected for full-text assessment after applying the inclusion criteria. Eleven studies described the efficacy of speech function: two for motility factors and nine for organic factors (with overlap). Thirteen studies described the effectiveness of swallowing function, four related to motility factors, and ten for organic factors (with overlap). Several studies have demonstrated that PAP effectively restores articulation and swallowing in patients with impaired tongue function after glossectomy for oropharyngeal cancer, sequelae of cranial nerve disease, or neuromuscular disease. However, few papers describe the scope of glossectomy and tongue movement restrictions, so it is impossible to describe the adaptation criteria, effects, and limitations. In this review, most case reports and cross-sectional studies did not provide information on the fabrication methods of PAP or the dentistsʼ experience. Thus, the effect of bias on palatal morphology in PAP patients remains unclear. Conclusions: The number of patients with dysarthria and dysphagia is increasing worldwide, similar to what is already occurring in Japan. Therefore, additional high-quality studies on the effects of PAP are required.
(Keyword)
Palatal augmentation prosthesis / Tongue dysfunction / Literature review
Yoshihiro Tagami, Keiko Fujimoto, Takaharu Goto, Hideki Suito, Kan Nagao and Tetsuo Ichikawa : Can Measurement of Ultrasonic Echo Intensity Predict Physical Frailty in Older Adults?, Diagnostics, Vol.13, No.4, 675, 2023.
(Summary)
Echo intensity (EI) of the tongue in ultrasonography is an easy and quantitative assessment of tongue function. Elucidating the relationship between EI and frailty, is expected to aid in the early detection of frailty and oral hypofunction in older adults. We assessed tongue function and frailty in older outpatients visiting a hospital. The subjects were 101 individuals aged 65 or older (35 men and 66 women, mean age 76.4 ± 7.0 years). Tongue pressure and EI were measured as assessments of tongue function and grip strength, and Kihon Checklist (KCL) scores were measured as assessments of frailty. In women, a significant correlation was not found between the mean EI and grip strength, whereas a significant correlation was noted between each score of the KCL and the mean EI; the scores increased as the mean EI increased. A significant positive correlation was found between tongue pressure and grip strength, but no significant correlation was observed between tongue pressure and the KCL scores. In men, no significant correlation was found between tongue assessments and frailty, except for a significant positive correlation between tongue pressure and grip strength. The results of this study suggest that EI of the tongue is positively associated with physical frailty in women and may be useful for early detection of physical frailty status.
Takahiro Kishimoto, Takaharu Goto and Tetsuo Ichikawa : Stress Reduction Effects during Block-Tapping Task of Jaw in Healthy Participants: Functional Near-Infrared Spectroscopy (fNIRS) Measurements of Prefrontal Cortex Activity, Brain Sciences, Vol.12, No.12, 1711, 2022.
(Summary)
The purpose of this study was to explore the influence of simple jaw opening and closing task of chewing movements on the activities of the prefrontal cortex (PFC) from the viewpoint of stress reduction. We measured cerebral blood flow (CBF) in the PFC during a block-tapping task of the jaw in healthy participants. Eleven young healthy individuals with normal dentition (7 males and 4 females, mean age 28.0 ± 3.7 years) volunteered for this study. CBF was measured using a wearable, functional near-infrared spectroscopy device. Measurements were taken using the central incisors and first molars at interocclusal distances of 5 and 10 mm. The participants were asked to bite a hard/soft block. CBF in all conditions showed limited variability or decreasing trend compared to resting state before the task. The main effect was observed for interocclusal distance ( = 0.008), and there were no significant differences for measurement area of the PFC, tooth type, and material type. An interaction was found between tooth type and material type. In conclusion, these results suggest that simple and rhythmical chewing motion has an effect of reducing CBF in the PFC and resting the PFC, which is an especially notable aspect of periodontal sensory information in the molar.
Yukako MASUTOMI, Takaharu Goto and Tetsuo Ichikawa : Investigation on the relationship between body posture and oral function in adolescents, The Journal of the Japanese Academy of Occulusion and Health, Vol.28, No.2, 12-15, 2022.
Adityakrisna Putra Yoshi Wigianto, Yuichi Ishida, Yuki Iwawaki, Takaharu Goto, Megumi Watanabe, Kazumitsu Sekine, Kenichi Hamada, Keiji Murakami, Hideki Fujii and Tetsuo Ichikawa : 2-methacryloyloxyethyl phosphorylcholine polymer treatment prevents Candida albicans biofilm formation on acrylic resin, Journal of Prosthodontic Research, Vol.67, No.3, 384-391, 2022.
(Summary)
We aimed to evaluate the effectiveness of photoreactive 2-methacryloyloxyethyl phosphorylcholine (MPC) in inhibiting Candida albicans biofilm formation on polymethyl methacrylate (PMMA) and assess its mechanism and need for re-application by evaluating its interaction with salivary mucin and durability during temperature changes. PMMA discs were used as specimens. The MPC coating was applied using the spray and cure technique for the treatment groups, whereas no coating was applied to the control. The MPC treatment (MT) groups were further differentiated based on the number of thermal cycles involved (0, 1000, 2500, and 5000). The optical density was measured to assess mucin adsorption (MA). Contact angle (CA) was calculated to evaluate surface hydrophilicity. The presence of MPC components on the PMMA surface was assessed using X-ray photoelectron spectroscopy (XPS). C. albicans biofilms were evaluated qualitatively (scanning electron microscope images) and quantitatively (colony-forming units (CFUs)). Statistical analysis was conducted using two-way analysis of variance and Tukey's multiple comparison test. MA rate and CA increased significantly in the MT groups, which exhibited significantly fewer CFUs and thinner biofilms than those of the control group. Based on the XPS, MA, and CFU evaluations, the durability and efficacy of the MPC coating were considered stable up to 2500 thermal cycles. Additionally, a significant interaction was observed between mucin concentration and MPC efficacy. The photoreactive MPC coating, which was resistant to temperature changes for approximately 3 months, effectively prevented C. albicans biofilm formation by modifying surface hydrophilicity and increasing mucin adsorption.
Adityakrisna Putra Yoshi Wigianto, Yuichi Ishida, Takashi Matsuda, Takaharu Goto, Megumi Watanabe and Tetsuo Ichikawa : Novel Magnetic Attachment System Manufactured Using High-Frequency Heat Treatment and Stamp Technique: Introduction and Basic Performance, Dentistry Journal, Vol.10, No.5, 75, 2022.
(Summary)
Recently, a novel magnetic attachment with extremely low cost and high performance was developed. This article aims to introduce a novel magnetic attachment and to evaluate its basic eligibility for denture retention in clinical practice. The novel magnetic attachment system used in this study was the direct-bonding root-keeper-type Magteeth™ MT800 (MagneDesign, Nagoya, Japan). The retentive force without displacement (position 0) and after horizontal displacement to positions 0.5, 1, 1.5, 2, 2.5, and 3 mm were measured. The values relative to the retentive force without displacement were gradually decreased to 82.7 ± 16.3%, 68.8 ± 17.1%, 62.4 ± 15%, 47.2 ± 13.1%, 35.7 ± 9.9%, and 20.7 ± 6.5%, respectively. The retentive force and magnetic field strength did not change significantly after the load test (100 N load, 10,000 times). No new gap between the metal and resin was found in the root keeper- and magnet assembly-embedded blocks after the load test. Some scratches on magnetic assembly and root keeper surface, while no change in the resin texture after the load test were observed. Based on the findings of this preliminary study, this novel low-cost magnetic attachment exhibited favorable retention, strength, and durability for clinical use.
Tetsuo Ichikawa, Takaharu Goto, Takahiro Kishimoto, Yuichi Ishida and Megumi Watanabe : Does Prosthodontic Treatment Improve the Nutrition Status in the Elderly? Literature Review, Journal of Food and Nutrition Research, Vol.10, No.1, 26-31, 2022.
Yoshihiro Tagami, Keiko Fujimoto, Takaharu Goto, Hideki Suito, Kan Nagao and Tetsuo Ichikawa : Measurement of ultrasonic echo intensity predicts the mass and strength of the tongue muscles in the elderly, Journal of Oral Science, Vol.64, No.1, 44-48, 2022.
(Summary)
The purpose of this study was to investigate the relationship between the echo intensity (EI) on ultrasound images of the tongue, tongue thickness, and tongue pressure to examine the effectiveness of EI measurement for assessing the tongue function. A total of 100 elderly outpatients were enrolled. Tongue thickness and EI were measured using ultrasonography. The distance from mylohyoid muscle surface to dorsal surface of the tongue was measured for tongue thickness. Subsequently, this area was vertically divided into four areas: top of tongue dorsal side (DT), bottom of tongue dorsal side (DB), top of basal tongue side (BT), and bottom of basal tongue side (BB), and the EI was measured in each area. The mean EIs of DT and DB were lower than those of BT and BB. In the three areas apart from BB, the EI decreased with an increase in tongue thickness. In particular, a significant correlation between the EI in DB and tongue thickness was found. In all areas, the EI decreased with an increase in tongue pressure. The results of this study suggested that the measurement of EI could be an important indicator for assessing the tongue function in the elderly.
Takaharu Goto and Tetsuo Ichikawa : Relationship between oral susceptibility assessment and prefrontal cortex blood flow during occlusal force maintenance tasks, The Journal of the Japanese Academy of Occulusion and Health, Vol.27, No.2, 8-12, 2021.
(Summary)
<p>The purpose of this study was to clarify the relationship between the periodontal tactile sensation and the activity of the prefrontal cortex. Eleven young, healthy Japanese participants (mean age 28.0±3.7 years) volunteered to participate in this study. We tested either the left side central incisors or the first molars. The periodontal tactile sensation of each tooth was evaluated using calibrated monofilaments (von Frey hairs). A magnitude estimation method was used as a psychophysical method, and the periodontal ligament tactile and periodontal tactile sensation values were determined by Stevens' power law. Prefrontal cortex activation was evaluated using a wearable functional near-infrared spectroscopy device that measured cerebral blood flow, and the experimental task involved maintaining occlusal force within an instructed range. The logarithmic values of the physical and sensory quantities of periodontal tactile sensation showed a linear relationship, and had a significantly high correlation coefficient. Regarding the periodontal tactile sensation values, no significant difference was found between the central incisors and first molars. In the molar teeth, negative correlations were found between the periodontal tactile sensation values and the cerebral blood flow in all measurement fields. Moreover, the mean occlusal force value of molars was below the instructed range, and showed significantly lower values compared to those of anterior teeth. Based on the above results, it was shown that Stevens' power law can be applied to periodontal tactile sensation, and the periodontal tactile sensation value in molars calculated from Stevens' power law is related to the cerebral blood flow in the prefrontal cortex and inhibition of occlusal force. The site-specific importance of the periodontal tactile sensation value was suggested during the task of maintaining occlusal force.</p>
Wigianto Yoshi Putra Adityakrisna, Takaharu Goto, Yuki Iwawaki, Yuichi Ishida, Megumi Watanabe and Tetsuo Ichikawa : Treatment outcomes of implant-assisted removable partial denture with distal extension based on the Kennedy classification and attachment type: a systematic review, International Journal of Implant Dentistry, Vol.7, No.1, 111, 2021.
(Summary)
Implant-assisted removable partial dentures (IARPDs) have recently become popular, but little information is available on the treatment outcomes based on the Kennedy classification and attachment types. The objective of this review was to evaluate the treatment outcomes of IARPD delivered for distal extension edentulous areas based on the differences in the Kennedy classification and attachment type. English-language clinical studies on IARPD published between January 1980 and February 2020 were collected from MEDLINE (via PubMed), the Cochrane Library (via the Cochrane Central Register of Controlled Trials), Scopus online database, and manual searching. Two reviewers selected the articles based on pre-determined inclusion and exclusion criteria, followed by data extraction and analysis. Eighty-one studies were selected after evaluating the titles and abstracts of 2410 papers. Nineteen studies were finally included after the perusal of the full text. Fourteen studies focused on Class I, 4 studies investigated both Class I and II, and only 1 study was conducted on Kennedy's class II. Eight types of attachments were reported. The ball attachment was the most frequently used attachment, which was employed in 8 of the included studies. The implant survival rate ranged from 91 to 100%. The reported marginal bone loss ranged from 0.3 mm to 2.30 mm. The patient satisfaction was higher with IARPD than with conventional RPDs or that before treatment. The results of prosthetic complications were heterogeneous and inconclusive. IARPD exhibited favorable clinical outcomes when used as a replacement for distal extension edentulous areas. The comparison between the clinical outcomes of Kennedy's class I and II was inconclusive owing to the lack of studies focusing on Kennedy Class II alone. The stud attachment was the most commonly used type in IARPDs. Overall, the different attachment systems did not influence the implant survival rate and patient satisfaction. Further high-quality studies are needed to investigate the attachment systems used in IARPD.
Mio Kitamura, Takaharu Goto, Shinji Fujiwara and Yasuhiko Shirayama : Did Kayoinoba Prevent the Decline of Mental and Physical Functions and Frailty for the Home-Based Elderly during the COVID-19 Pandemic?, International Journal of Environmental Research and Public Health, Vol.18, No.9502, 2021.
(Summary)
The purpose of this study is to grasp the management situation of "" under the conditions of self-quarantine due to the COVID-19 pandemic. It is also to clarify the efficacy of "" using the Kihon Checklist (KCL) for the assessment of mental and physical functions in the elderly. The respondents were 136 elderly people aged 65 years and over who lived in A City, a standard rural area in Japan. The age, gender, living style, affluence for living, and the frequency of participation in "" were examined by using the KCL as a self-completed questionnaire. Finally, 101 respondents were included in the final analysis. There was no difference in the participation status before and after the spread of COVID-19. The frailty ratio tended to decrease from 23.8% to 19.8% between the two periods, but there was no difference in the frailty ratio. It is suggested that the participants in "" may have suppressed the deterioration of mental and physical conditions, excluding physical activity. This would prevent the frailty of the elderly, even during self-quarantine due to the spread of COVID-19.
Keiko Fujimoto, Yuki Iwawaki, Takaharu Goto, Takahiro Kishimoto, Kan Nagao and Tetsuo Ichikawa : Objective Assessment of Poor Oral Hygiene Using the ATP Swab Test in the Elderly, Japanese Journal of Gerodontology, Vol.36, No.1, 44-52, 2021.
(Summary)
<p> Purpose:The purpose of this study was to evaluate the assessment of poor oral hygiene using the ATP swab test.</p><p> Method:A total of 102 consecutive elderly outpatients aged ≥65 years who visited for maintenance were enrolled between October 2019 and April 2020. The evaluation of poor oral hygiene included measurements of:Tongue Coating Index(TCI), number of bacteria by a rapid oral bacterial detection device(Bacterial Counter DU-AA01NP-H;Panasonic Health Care, Japan), and amount of ATP+AMP by the ATP swab test(Lumitester;Kikkoman, Japan). The specimens were a gargle solution rinsed with 10 mL of water for 5 seconds as soon as the patients came to the hospital or a cotton swab wiped on the tongue dorsum. The subjective assessment of hygiene of the oral mucosa and dentures was rated on a 5-point scale.</p><p> Results:In the assessment of tongue dorsum hygiene, the number of bacteria and the amount of ATP+AMP were significantly correlated with TCI. There was also a significant correlation between the number of bacteria and the amount of ATP+AMP.</p><p> Conclusion:The results of this study suggested that the ATP swab test might be used to objectively assess overall poor oral hygiene, including food residues.</p>
(Keyword)
elderly / poor oral hygiene / ATP swab test / bacterial counts / Tongue Coating Index
Takaharu Goto, Nobuaki Higaki, Takahiro Kishimoto, Yoritoki Tomotake and Tetsuo Ichikawa : Does periodontal tactile input uniquely increase cerebral blood flow in the prefrontal cortex?, Brain Sciences, Vol.10, No.8, E482, 2020.
(Summary)
We previously studied the effect of peripheral sensory information from sensory periodontal ligament receptors on prefrontal cortex (PFC) activity. In the dental field, an alternative dental implant without periodontal sensation can be applied for missing teeth. In this study, we examine whether periodontal tactile input could increase cerebral blood flow (CBF) in the PFC against elderly patients with dental implants lacking periodontal tactile (implant group), elderly individuals with natural teeth (elderly group), and young individuals with natural teeth (young group). The experimental task of maintaining occlusal force as closed-loop stimulation was performed. Compared with the young group, the elderly group showed significantly lower CBF. Contrastingly, compared with the young group, the implant group showed significantly lower CBF. There were no significant differences between the elderly and implant groups. Regarding the mean occlusal force value, compared with the young group and the elderly group, the implant group had a numerically, but not significantly, larger occlusal force exceeding the directed range. In conclusion, the periodontal tactile input does not uniquely increase PFC activity. However, increased CBF in the PFC due to the periodontal tactile input in the posterior region requires existing attention behavior function in the PFC.
Hihara Tsukasa, Takaharu Goto and Tetsuo Ichikawa : Assessment of potential clinical cascade between oral hypofunction and physical frailty: Covariance structure analysis in a cross-sectional study, Journal of Oral Rehabilitation, Vol.47, No.1, 61-66, 2020.
(Summary)
No report has yet examined the impact of oral hypofunction on physical frailty in relation to intra-relationships of physical frailty assessment items. The purpose of this study was to verify the potential of a clinical cascade between oral hypofunction and physical frailty, and especially to support the hypothesis that the influence of oral hypofunction on physical frailty is greater than the intra-relationships among elements of physical frailty and that sex differences significantly affect these relationships. The participants were 272 older adults (101 men and 171 women; mean age 75.1 ± 7.5 years). Maximum occlusal force (MOF) and oral dryness (OD), as indicators of oral hypofunction, and grip strength (GS) and walking speed (WS), as indicators of physical frailty, were measured. Mutual relationship of four variables was verified using covariance structure analysis. In men, three paths from MOF to WS and GS and from WS to GS were confirmed, and those from MOF to WS and from WS to GS were found to be significant (P < .01). In women, three paths from MOF to WS and GS and from WS to GS were also confirmed, as with the men, and those from MOF to WS and from MOF to GS were found to be significant (P < .01). Model adaptability was shown to be good for both men and women. The results suggest our hypothesis was verified, and it is expected that the early detection of oral hypofunction, that is MOF, may be important for assessing physical frailty, especially in women.
(Keyword)
Aged / Aged, 80 and over / Bite Force / Cross-Sectional Studies / Female / Frail Elderly / Frailty / Geriatric Assessment / Humans / Male
Takaharu Goto and Tetsuo Ichikawa : 高齢者における身体的能力の低下とその意識との関係:咬合力，握力，歩行速度, The Journal of the Japanese Academy of Occulusion and Health, Vol.25, No.2, 39-43, 2019.
The prefrontal cortex (PFC) plays an important role in several cognitive functions, such as planning, decision making, and social behavior. We previously reported that periodontal sensory input significantly increases PFC activity during the motor task of maintaining occlusal (biting) force. However, the relationships between periodontal sensation, PFC activity, and the performance of motor tasks have not been evaluated in detail. Therefore, using functional near-infrared spectroscopy, we investigated PFC activity by monitoring changes in cerebral blood flow (CBF) to specific areas of the PFC that corresponded to changes in occlusal force generated during four different biting tasks: (1) occlusion with the central incisor with an interocclusal distance of 5 mm (BI-5 mm); or (2) 10 mm (BI-10 mm); (3) occlusion with the first molars with an interocclusal distance of 5 mm (BM-5 mm), or (4) 10 mm (BM-10 mm). Occlusion of molars generated increased PFC regional CBF as the interocclusal distance decreased (BM-10 mm vs BM-5 mm). No significant differences in CBF during occlusion of incisors were found when comparing 5 mm and 10 mm intercostal distances (BI-5 mm vs BI-10 mm). The mean occlusal force generated by BM-5 mm occlusion was significantly lower than that generated by BM-10 mm occlusion. Taken together, our results suggest that the PFC decreases efferent signaling to motor units, to reduce occlusal force generated when periodontal sensation, which is greater when the interocclusal distance is reduced, is primarily responsible for maintaining occlusal force in the absence of sensations from the temporomandibular joint and muscle spindles.
Tsukasa Hihara, Takaharu Goto and Tetsuo Ichikawa : Investigating eating behaviors and symptoms of oral frailty using questionnaires, Dentistry Journal, Vol.7, No.3, 66, 2019.
(Summary)
A questionnaire survey was conducted to investigate eating behavior and the subjective symptoms of oral frailty, and to examine the relationship between them. A total of 744 subjects with ages over 65 years were included. The questionnaire comprised 18 question items indicating eating behavior and seven question items indicating oral frailty. All items were assessed according to 4 grades on a scale of 1 (not applicable) to 4 (applicable). The total score of oral frailty gradually increased with age. Regarding the scores for "eating recognition" and "eating habits", no changes were observed, however the scores for "eating action" demonstrated a decreasing tendency with age and the scores of 85 years age group was significantly lower than the 65-69, 70-74, and 75-79 years age groups. As a result of multiple regression analysis, among the significant independent variable, the scores of "I do not chew foods well" under the category of "eating action" showed the highest standard partial regression coefficients for dependent variable of symptoms of oral frailty. The significant association was found between the eating behavior and subjective symptoms of oral frailty, and this study suggests that the good chewing habit might be an important criterion for the prevention of oral frailty.
Yasuhiko Shirayama, 湯浅 雅志, 樫森 節子, Mio Kitamura, Takaharu Goto, 寺西 彩, Shizuko Yanagisawa, Yuko Takeuchi, Tetsuo Ichikawa and 臼谷 佐和子 : The aplication and usefulness of virtual reality aimd at encouraging an understanding of and reducing and eliminating prejudice dementia patients among local residents, Japanese Journal of Geriatrics, Vol.56, No.2, 156-163, 2019.
(Summary)
To demonstrate the usefulness of a virtual reality device that authentically portrays the emotions of dementia patients and their families (VR Dementia Experience) for encouraging an understanding of and reducing and eliminating prejudice towards dementia patients among local residents. In Prefecture T, Town N, 85 residents of Neighborhood A were chosen as the intervention group, and 95 residents of Neighborhood B were chosen as the non-intervention group. The VR Dementia Experience was provided only to the residents of Neighborhood A. Residents of both neighborhoods completed a 35-item questionnaire regarding their degree of understanding and prejudice towards dementia patients before and after the intervention. Seventy-seven residents of Neighborhood A and 82 residents of Neighborhood B were analyzed. Their gender, age, and pre-intervention test baseline values were equivalent in the degree of understanding and prejudice. Significant increases were observed in 9 of 35 items for Neighborhood A residents (7 understanding-related, 2 prejudice-related) and 2 items for Neighborhood B residents (1 understanding-related, 1 prejudice-related). To ascertain the usefulness of the VR Dementia Experience, we compared the number of items with a significant increase: 9/35 (25.7%) in Neighborhood A and 2/35 (5.7%) in Neighborhood B. An effect (≥ 20%) was observed among the residents of Neighborhood A. Furthermore, after exposure to the VR Dementia Experience, the connection between understanding, prejudice, and dementia was strengthened among the residents of Neighborhood A compared to the residents of Neighborhood B. The VR Dementia Experience is a useful tool for encouraging an understanding of and reducing and eliminating prejudice towards dementia patients among local residents. However, to encourage the widespread usage of the technology, we should compare results with other public awareness campaigns as well as make improvements to the device and its VR content.
Yuki Iwawaki, Takashi Matsuda, Kosuke Kurahashi, Tsuyoshi Honda, Takaharu Goto and Tetsuo Ichikawa : Effect of the temperature of water on ultrasonic denture cleaning, Journal of Oral Science, Vol.61, No.1, 140-145, 2019.
(Summary)
Denture plaque is a biofilm composed of various microorganisms aggregated with saliva. Various denture cleansers and cleaning apparatuses have been developed and studied. However, the optimum water temperature for denture cleaning is unknown. Therefore, the present study investigated the effects of water temperature during ultrasonic denture cleaning. In vitro, resin disks with artificial Candida albicans biofilm were pressed onto Candida GE media after ultrasonic cleaning with water at different temperatures for 5 min. The media were subsequently cultured at 37°C for 24 h. The colonies formed were observed and colony areas were quantified using ImageJ software (US National Institutes of Health, Bethesda, MD, USA). In situ, the bacterial count and degree of cleanliness on the tissue surface of maxillary dentures were measured before and after ultrasonic cleaning with water at different temperatures for 5 min. Changes in bacterial counts and cleanliness were calculated for each temperature. The ratio of the area occupied by bacterial colonies in vitro and reduction rates in situ after cleaning with warm water were markedly less than those observed after cleaning with cold water. Therefore, ultrasonic denture cleaning with warm water is more effective.
(Keyword)
Bacteria / Biofilms / Candida albicans / Colony Count, Microbial / Culture Media / Dentures / Disinfection / Hot Temperature / Ultrasonic Waves / Water
Yuki Iwawaki, Muraoka Yuki, Higashiyama Hiroaki, Takahiro Kishimoto, Liu Lipei, Takaharu Goto and Tetsuo Ichikawa : Comparison between two assessment tests for oral hygiene: adenosine triphosphate + adenosine monophosphate swab test and bacteria number counting by dielectrophoretic impedance measurement, Dentistry Journal, Vol.7, No.1, 10, 2019.
Takuro Baba, Takaharu Goto, Keiko Fujimoto, Hideki Suito, Kazutomo Yagi, Kan Nagao and Tetsuo Ichikawa : Geniohyoid muscle affects directly masticatory function: Evaluation using a decision tree analysis, The International Journal of Prosthodontics, Vol.31, No.6, 569-572, 2018.
(Summary)
To clarify the effect of geniohyoid (GH) muscle morphology and related function on masticatory ability using a decision-tree analysis. A total of 103 participants were enrolled. A cross-sectional area (CSA) of the GH muscle, neck circumference, body mass index, tongue pressure, jaw opening strength, and masticatory ability score were measured. The CSA of the GH muscle was selected as an independent variable for the first layer of the decision tree, with masticatory score as the dependent variable. These data suggest that the CSA of the GH muscle may have a large impact on the masticatory ability score when evaluating masticatory ability.
(Keyword)
Body Mass Index / Decision Trees / female / Humans / male / Mastication / Middle Aged / Muscle Strength / Neck Muscles / Pharyngeal Muscles / Pressure / Range of Motion, Articular
Kohsuke Kurahashi, Yuki Iwawaki, Takashi Matsuda, Takaharu Goto, 石田 雄一, Teruaki Ito and Tetsuo Ichikawa : Duplicate complete dentures made by general digital devices: Evaluation of material properties and clinical trial, Annals of Japan Prosthodontic Society, Vol.9, No.4, 357-364, 2017.
(Summary)
<p><b>Purpose:</b> The purpose of this study was to investigate the validity of the process of duplicating complete dentures using general digital devices through the following tests: cytotoxicity test of materials used, adhesion test of materials to a silicone impression material and a self-curing resin, and questionnaires to operators on duplicate dentures in clinical situations.</p><p><b>Methods: </b>The cell viability of mouse fibroblast-like cells in acrylonitrile- butadiene-styrene (ABS) and polylactic acid (PLA) were evaluated as a cytotoxicity test. The tensile strength between the silicone impression material/self-curing resin and ABS/PLA specimen was measured as adhesive strength using a universal testing machine. Six practitioners who used duplicate PLA complete dentures in 7 patients were asked to evaluate the duplicate denture using the original questionnaire.</p><p><b>Results:</b> The cytotoxicity test showed that the cell viabilities in ABS and PLA were similar to that in acrylic resin at the cell culture times of 24, 48 and 72 hours. The adhesion test showed that the adhesive strength between the ABS/PLA and silicone impression material was significantly lower than that between the conventional self-curing resin and silicone impression material. Although the adhesive strength between the PLA and self-curing resin was low, there was no significant difference between the ABS and self-curing resin. The results of the questionnaire showed that the duplicate denture made of PLA would be of similar value compared to the conventional duplicate denture made of acrylic resin.</p><p><b>Conclusions:</b> The present study suggests that the duplicate complete dentures made by our proposed digital process are clinically effective.</p>
Shizuko Yanagisawa, Masanori Nakano, Takaharu Goto, Masami Yoshioka and Yasuhiko Shirayama : Development of an oral assessment sheet for evaluating older adults in nursing homes, Research in Gerontological Nursing, Vol.10, No.5, 234-239, 2017.
(Summary)
A new general use oral assessment sheet (OAS), comprising three items each in three categories (i.e., oral hygiene, biting and chewing, and oral function), was developed to improve the oral health of older adults requiring nursing care. Seventy-nine care workers used the assessment sheet to evaluate oral conditions in 188 institutionalized older adults. Forty-five care workers and three dental professionals then assessed oral conditions in 45 institutionalized older adults using the test-retest method before and after dental professional guidance. Cronbach's alpha of the OAS was 0.72, and 0.65, 0.57, and 0.82 for the three subcategories of oral hygiene, biting and chewing, and oral function, respectively. After dental professional intervention, absolute and relative agreement coefficients increased to more than 0.6 and 0.89, respectively. Reliability and validity of the OAS were verified, and difficulties in oral assessment experienced by care workers were identified. [Res Gerontol Nurs. 2017; 10(5):234-239.].
(Keyword)
Aged / Aged, 80 and over / Dental Care for Aged / Diagnosis, Oral / Female / Geriatric Assessment / Humans / Male / Mastication / Nursing Homes / Oral Health / Oral Hygiene
Sachie Wada, Takaharu Goto, Keiko Fujimoto, Megumi Watanabe, Kan Nagao, Atsuko Nakamichi and Tetsuo Ichikawa : Changes in food bolus texture during mastication, Journal of Texture Studies, Vol.48, No.2, 171-177, 2017.
(Summary)
The purpose of this study was to survey the changes that occur in bolus texture from intake to swallowing during the mastication process for four types of food materials and to identify how texture is related to the number of chews. We recruited 15 young Japanese participants for this study. The subjects were asked to spit the food bolus just before swallowing when eating four different foods: cracker, boiled rice, hard gelatine gel, and soft gelatine gel. Three physical properties (hardness, adhesiveness, and cohesiveness) were measured in the bolus after being chewed for 25, 50, 75, 100, and 125% of the normal number of chews. Occlusal force and pressure as well as stimulated whole saliva volume were also measured. Extensive variation in the number of chews existed between subjects, but minimal intra-subject variation was observed. Hardness was observed to decrease, whereas cohesiveness and adhesiveness increased in a chew-dependent manner for the cracker, soft gelatine gel, and hard gelatine gel, but not boiled rice. Bolus texture appears to be largely related to the number of chews. Hardness also tended to be influenced by occlusion. The adhesiveness and hardness of the boiled rice were also greatly influenced by saliva volume and occlusal force, respectively. Hardness is an important rheological factor in food bolus texture and likely plays a significant role in determining the appropriate number of chews. Adhesiveness and cohesiveness appear to be secondary factors in this process. We propose a model of oral processing for application in determining the appropriate number of chews for an individual. Hardness appears to be an important rheological factor in food bolus texture, with adhesiveness and cohesiveness being secondary aspects. When food is hard or difficult to swallow, chewing behavior will likely be more influenced by the perception of bolus texture.
Kosuke Kurahashi, Takashi Matsuda, Takaharu Goto, Yuichi Ishida, Teruaki Ito and Tetsuo Ichikawa : Duplication of complete dentures using general-purpose handheld optical scanner and 3-dimensional printer: Introduction and clinical considerations, Journal of Prosthodontic Research, Vol.61, No.1, 81-86, 2017.
(Summary)
To introduce a new clinical procedure for fabricating duplicates of complete dentures by bite pressure impression using digital technology, and to discuss its clinical significance. The denture is placed on a rotary table and the 3-dimensional form of the denture is digitized using a general-purpose handheld optical scanner. The duplicate denture is made of polylactic acid by a 3-dimensional printer using the 3-dimensional data. This procedure has the advantages of wasting less material, employing less human power, decreasing treatment time at the chair side, lowering the rates of contamination, and being readily fabricated at the time of the treatment visit.
Tsuyoshi Honda, Takuro Baba, Keiko Fujimoto, Takaharu Goto, Kan Nagao, Masafumi Harada, Eiichi Honda and Tetsuo Ichikawa : Characterization of Swallowing Sound: Preliminary Investigation of Normal Subjects, PLoS ONE, Vol.11, No.12, e0168187, 2016.
(Summary)
The purpose of this study was to characterize the swallowing sound and identify the process of sound generation during swallowing in young healthy adults. Thirty-three healthy volunteers were enrolled and allocated into three experimental groups. In experiment 1, a microphone was attached to one of eight cervical sites in 20 subjects, participants swallowed 5 ml water, and the sound waveform was recorded. In experiment 2, 10 subjects swallowed either 0, 5, 10, or 15 ml water during audio recording. In addition, participants consumed the 5 ml bolus in two different cervical postures. In experiment 3, the sound waveform and videofluoroscopy were simultaneously recorded while the three participants consumed 5 ml iopamidol solution. The duration and peak intensity ratio of the waveform were analyzed in all experimental groups. The acoustic analysis of the waveforms and videofluoroscopy suggested that the swallowing sound could be divided into three periods, each associated with a stage of the swallowing movement: the oral phase comprising posterior tongue and hyoid bone movement; the pharyngeal phase comprising larynx movement, hyoid bone elevation, epiglottis closure, and passage of the bolus through the esophagus orifice; and the repositioning phase comprising the return of the hyoid bone and larynx to their resting positions, and reopening of the epiglottis. Acoustic analysis of swallowing sounds and videofluoroscopy suggests that the swallowing sound could be divided into three periods associated with each process of the swallowing movement: the oral phase comprising the posterior movement of the tongue and hyoid bone; the pharyngeal phase comprising the laryngeal movement, hyoid bone elevation, epiglottis closure, and the bolus passage to the esophagus orifice; and the repositioning phase comprising the repositioning of the hyoid bone and larynx, and reopening of the epiglottis.
Takaharu Goto, Nobuaki Higaki, Kazutomo Yagi, Yuichi Ishida, Megumi Watanabe, Kan Nagao and Tetsuo Ichikawa : An innovative masticatory efficiency test using odor intensity in the mouth as a target marker: a feasibility study, Journal of Oral Rehabilitation, Vol.43, No.12, 883-888, 2016.
(Summary)
A large number of studies have reported the findings for masticatory efficiency tests; however, some objective masticatory efficiency tests have a drawback, in that subjects are required to spit out the test material. This study examined the possibility of a masticatory efficiency test that evaluates the intensity of odours released when chewing an odour compound-containing material. A total of 20 volunteers were used in this study. The odour intensity in the breath after chewing a gum was measured by portable odour sensor device. The odour intensity after chewing the gum was measured over four chewing durations and at four intervals between spitting out and measurement of the odour intensity. The volume of stimulated saliva was measured by calculating the difference in the weight of the gauze before and after chewing to examine the effect of saliva flow. With an increase in chewing duration, odour intensity reduced. The odour intensity was the highest immediately after chewing. There was a positive correlation between odour intensity and gummy jelly-related masticatory efficiency test value (G-METV), which was significant for 10-s chewing. The regression equation was calculated from three objective variables of odour intensity and G-METV as dependent variable. Pearson's correlation coefficient between G-METV and the odour intensity-related masticatory efficiency value (O-METV) was 0·68. The coefficient of variation of O-METV was significantly lower than that of G-METV. These results suggest that the masticatory performance can be estimated by measuring the odour intensity immediately after chewing food containing odour compounds for 10 s.
Nobuaki Higaki, Takaharu Goto and Tetsuo Ichikawa : Periodontal tactile input activates the prefrontal cortex, Scientific Reports, Vol.6, 36893, 2016.
(Summary)
The prefrontal cortex (PFC) plays a role in complex cognitive behavioural planning, decision-making, and social behaviours. However, the effects of sensory integration during motor tasks on PFC activation have not been studied to date. Therefore, we investigated the effect of peripheral sensory information and external information on PFC activation using functional near-infrared spectroscopy (fNIRS). Cerebral blood flow (CBF) was increased around bilateral Brodmann areas 46 and 10 during visual and auditory information integration during an occlusal force (biting) task. After local anesthesia, CBF values were significantly decreased, but occlusal force was similar. In conclusion, the effects of peripheral sensory information from the periodontal ligament and external information have minimal impacts on occlusal force maintenance but are important for PFC activation.
Yuichi Ishida, Kumer Kiran, Takaharu Goto, Megumi Watanabe, Wigianto Rudi, Kan Nagao and Tetsuo Ichikawa : Magnet-retained two-mini-implant overdenture: Clinical and mechanical consideration., Dentistry Journal, Vol.4, No.4, 35, 2016.
(Summary)
Two-implant overdentures have become the accepted treatment for restoring mandibular edentulism. The dimensions of regular implants sometimes limit their use, such as in the case of narrow ridges. Mini-implants with reduced diameters (less than 3.0 mm) enable insertion into narrow ridges. A magnet-retained two-mini-implant overdenture system was developed and is described in this paper. Additionally, we describe a clinical mandibular procedure using the system and evaluate its biomechanical performance.
Keiko Fujimoto, Norikazu Minami, Takaharu Goto, Yuichi Ishida, Megumi Watanabe, Kan Nagao and Tetsuo Ichikawa : Hardness, cohesiveness, and adhesiveness of oral moisturizers and denture adhesives: selection criteria for denture wearers., Dentistry Journal, Vol.4, No.4, 34, 2016.
(Summary)
The mechanical properties of seven denture adhesives and eight oral moisturizers, all of which are commercially available, were evaluated using a texture pro le analysis. A new assessment chart is proposed for the selection criteria of denture adhesive and oral moisturizers using a radar chart with three axes: hardness, cohesiveness, and adhesiveness.
Takashi Matsuda, Takaharu Goto, Kazutomo Yagi, Toshiya Kashiwabara and Tetsuo Ichikawa : Part-digitizing system of impression and interocclusal record for complete denture fabrication, Journal of Prosthodontics, Vol.25, No.6, 503-509, 2016.
(Summary)
Few studies have reported the application of digital technology to removable dentures, particularly for the process of impression and interocclusal recording for complete denture fabrication. This article describes a part-digitizing system of impression and interocclusal records for complete denture fabrication. The denture foundation area in an edentulous mouth, including the border areas and residual ridge, is outlined by tracing the surfaces with a 3-D pen-type digitizer. Specialized trays for final impressions and interocclusal records were generated using computer-aided design and manufactured using the digital data. Final impression and interocclusal records were carried out using these specialized trays. The computer-aided method using preliminary digital impressions and specialized trays would be feasible for clinical use for complete denture fabrication.
Takashi Matsuda, Takaharu Goto, Kosuke Kurahashi, Toshiya Kashiwabara, Megumi Watanabe, Yoritoki Tomotake, Kan Nagao and Tetsuo Ichikawa : Digital assessment of preliminary impression accuracy for edentulous jaws: Comparisons of 3-dimensional surfaces between study and working casts, Journal of Prosthodontic Research, Vol.60, No.3, 206-212, 2016.
(Summary)
The aim of this study was to compare 3-dimensional surfaces of study and working casts for edentulous jaws and to evaluate the accuracy of preliminary impressions with a view to the future application of digital dentistry for edentulous jaws. Forty edentulous volunteers were serially recruited. Nine dentists took preliminary and final impressions in a routine clinical work-up. The study and working casts were digitized using a dental 3-dimensional scanner. The two surface images were superimposed through a least-square algorithm using imaging software and compared qualitatively. Furthermore, the surface of each jaw was divided into 6 sections, and the difference between the 2 images was quantitatively evaluated. Overall inspection showed that the difference around residual ridges was small and that around borders were large. The mean differences in the upper and lower jaws were 0.26mm and 0.45mm, respectively. The maximum values of the differences showed that the upward change mainly occurred in the anterior residual ridge, and the downward change mainly in the posterior border seal, and the labial and buccal vestibules, whereas every border of final impression was shortened in the lower jaw. The accuracy in all areas except the border, which forms the foundation, was estimated to be less than 0.25mm. Using digital technology, we here showed the overall and sectional accuracy of the preliminary impression for edentulous jaws. In our clinic, preliminary impressions have been made using an alginate material while ensuring that the requisite impression area was covered.
Yuichi Ishida, 藤本 けい子, 檜垣 宜明, Takaharu Goto and Tetsuo Ichikawa : 審美歯治療のエンドポイントと評価方法, Annals of Japan Prosthodontic Society, Vol.8, No.2, 161-166, 2016.
48.
Takashi Matsuda, Takaharu Goto, Kosuke Kurahashi, Toshiya Kashiwabara and Tetsuo Ichikawa : Development of a digital impression procedure using photogrammetry for complete denture fabrication, International Journal of Computerized Dentistry, Vol.19, No.3, 193-202, 2016.
(Summary)
We developed an innovative procedure for digitizing maxillary edentulous residual ridges with a photogrammetric system capable of estimating three-dimensional (3D) digital forms from multiple two-dimensional (2D) digital images. The aim of this study was to validate the effectiveness of the photogrammetric system. Impressions of the maxillary residual ridges of five edentulous patients were taken with four kinds of procedures: three conventional impression procedures and the photogrammetric system. Plaster models were fabricated from conventional impressions and digitized with a 3D scanner. Two 3D forms out of four forms were superimposed with 3D inspection software, and differences were evaluated using a least squares best fit algorithm. The in vitro experiment suggested that better imaging conditions were in the horizontal range of ± 15 degrees and at a vertical angle of 45 degrees. The mean difference between the photogrammetric image (Form A) and the image taken from conventional preliminarily impression (Form C) was 0.52 ± 0.22 mm. The mean difference between the image taken of final impression through a special tray (Form B) and Form C was 0.26 ± 0.06 mm. The mean difference between the image taken from conventional final impression (Form D) and Form C was 0.25 ± 0.07 mm. The difference between Forms A and C was significantly larger than the differences between Forms B and C and between Forms D and C. The results of this study suggest that obtaining digital impressions of edentulous residual ridges using a photogrammetric system is feasible and available for clinical use.
Yuki Iwawaki, Noriko Mizusawa, Takeo Iwata, Nobuaki Higaki, Takaharu Goto, Megumi Watanabe, Yoritoki Tomotake, Tetsuo Ichikawa and Katsuhiko Yoshimoto : MiR-494-3p induced by compressive force inhibits cell proliferation in MC3T3-E1 cells., Journal of Bioscience and Bioengineering, Vol.120, No.4, 456-462, 2015.
(Summary)
Mechanical stimuli regulate fundamental cell processes such as proliferation, differentiation, and morphogenesis. We attempted to identify microRNA (miRNA) whose expression is changed during compressive treatment in MC3T3-E1, a pre-osteoblastic cell line. Microarray analysis followed by reverse transcription-quantitative polymerase chain reaction revealed that compressive force at 294 Pa for 24 h in MC3T3-E1 cells increased levels of miR-494-3p, miR-146a-5p, miR-210-3p, and miR-1247-3p. Among these miRNAs, miR-494-3p was found to inhibit cell proliferation in MC3T3-E1 cells. Furthermore, cells subjected to compressive force showed slower cell growth compared with control cells. Levels of mRNA for fibroblast growth factor receptor 2 (FGFR2) and Rho-associated coiled-coil kinase 1 (ROCK1), which were predicted to be targets of miR-494-3p, were decreased by compressive force or overexpression of miR-494-3p mimics in MC3T3-E1 cells. Furthermore, binding sites of miR-494-3p within 3'-untranslated regions of Fgfr2 and Rock1 were determined using luciferase reporter assay. In conclusion, compressive force affected expressions of several miRNAs including miR-494-3p in MC3T3-E1 cells. Compressive force might inhibit cell proliferation in osteoblasts by up-regulating miR-494-3p followed by FGFR2 and ROCK1 gene repressions.
Yoritoki Tomotake, Yuki Iwawaki, Takaharu Goto, 西中 英伸 and Tetsuo Ichikawa : インプラント上部構造における前装材破折と主機能部位との関連について, Journal of Japanese Society of Oral Implantology, Vol.28, No.3, 326-333, 2015.
Yuichi Ishida, Keiko Fujimoto, Nobuaki Higaki, Takaharu Goto and Tetsuo Ichikawa : End points and assessments in esthetic dental treatment., Journal of Prosthodontic Research, Vol.59, No.4, 229-235, 2015.
(Summary)
There are two key considerations for successful esthetic dental treatments. This article systematically describes the two key considerations: the end points of esthetic dental treatments and assessments of esthetic outcomes, which are also important for acquiring clinical skill in esthetic dental treatments. The end point and assessment of esthetic dental treatment were discussed through literature reviews and clinical practices. Before designing a treatment plan, the end point of dental treatment should be established. The section entitled "End point of esthetic dental treatment" discusses treatments for maxillary anterior teeth and the restoration of facial profile with prostheses. The process of assessing treatment outcomes entitled "Assessments of esthetic dental treatment" discusses objective and subjective evaluation methods. Practitioners should reach an agreement regarding desired end points with patients through medical interviews, and continuing improvements and developments of esthetic assessments are required to raise the therapeutic level of esthetic dental treatments.
Takaharu Goto, Atsuko Nakamichi, Megumi Watanabe, Kan Nagao, Miwa Matsuyama and Tetsuo Ichikawa : Influence of food volume per mouthful on chewing and bolus properties, Physiology & Behavior, Vol.141, 58-62, 2015.
(Summary)
Behaviors relating to food intake, i.e., speed of chewing, number of chews, and bite size, are important for decreasing energy intake, which might reduce excess body weight and thus metabolic risk. This study aimed at investigating the influence of mouthful volume on the number of chews and food bolus properties in addition to clarifying appropriate eating behaviors related to mouthful volume. Fifteen young Japanese women volunteered to participate. The subjects were asked to spit the food bolus in a glass dish just before swallowing when eating 3 different foods: boiled rice, fish sausage, and peanuts. The 3 physical properties of solidity, adhesiveness, and cohesiveness were measured in the bolus, and the number of chews was noted. The number of chews significantly increased with increasing mouthful volume with all 3 foods; conversely, the number of chews per unit of food weight (g) decreased significantly with boiled rice and fish sausage. Trends were observed for solidity and cohesiveness, which varied with increasing mouthful volumes. Decreased mouthful volume resulted in a greater number of chews per weight of food and more appropriate bolus properties; therefore, a change in mouthful volume could be a useful behavior modification for regulation of energy intake.
(Keyword)
Eating / Energy Intake / Feeding Behavior / Female / Food / Humans / Mastication / Young Adult
Takashi Matsuda, Takaharu Goto, 柏原 稔也 and Tetsuo Ichikawa : Literature Review of Setting the Occlusal Plane for Edentulous Patients, Journal of Oral Health and Biosciences, Vol.28, No.1, 13-19, 2015.
(Summary)
The maxillomandibular registration is one of important processes to achieve patientsatisfaction with the function and esthetics for complete denture fabrication. Over the years, clinical decision of vertical and horizontal jaw relationship has been mainly discussed in the maxillomandibular registration. With regard to the occlusal plane setting, many clinicians have believed to decide the occlusal plane parallel to Camper's plane, however there is little information on the effect of occlusal plane setting on clinical meanings and outcome. The aim of this study is to analyze published literature focusing on the occlusal plane and the related oral function and esthetics, and to clarify clinical implications of occlusal plane setting. Two databases, "PubMed" and "Japana Centra Revuo Medicina" were searched to retrieve research papers focusing on the occlusal plane.Seventy four papers were selected from the database, and they were reviewed.Literature reviews suggests that many landmarks were described on the occlusal plane setting for edentulous patients; and Camper's plane has been most frequently referred, showed a good result in function, but not always good in esthetics. The influence of occlusal plane setting on clinical results: oral function, esthetics, denture stability, and patient satisfaction after denture delivery has to be examined.
Takaharu Goto, Kan Nagao, Yuichi Ishida, Yoritoki Tomotake and Tetsuo Ichikawa : Influence of female attachment installation load on movement and resultant forces in implant overdentures, Journal of Prosthodontics, Vol.24, No.2, 156-163, 2015.
(Summary)
This in vitro study investigated the effect of attachment installation conditions on the load transfer and denture movements of implant overdentures, and aims to clarify the differences among the three types of attachments, namely ball, Locator, and magnet attachments. Three types of attachments, namely ball, Locator, and magnetic attachments were used. An acrylic resin mandibular edentulous model with two implants placed in the bilateral canine regions and removable overdenture were prepared. The two implants and bilateral molar ridges were connected to three-axis load-cell transducers, and a universal testing machine was used to apply a 50 N vertical force to each site of the occlusal table in the first molar region. The denture movement was measured using a G(2) motion sensor. Three installation conditions, namely, the application of 0, 50, and 100 N loads were used to install each attachment on the denture base. The load transfer and denture movement were then evaluated. The resultant force decreased with increasing installation load for all attachments. In particular, the resultant force on implants on the loading side of the Locator attachment significantly decreased when the installation load was increased from 0 to 50 N, and that for magnetic attachment significantly decreased when the installation load was increased from 50 to 100 N. For the residual ridges on the loading side, the direction of the forces for all attachments changed to downward with increasing installation load. Furthermore, the yaw Euler angle increased with increasing installation load for the magnetic attachment. Subject to the limitations of this study, the use of any installation load greater than 0 N is recommended for the installation of ball and Locator attachments on a denture base. Regarding magnetic attachments, our results also recommend installation on a denture base using any installation load greater than 0 N, and suggest that the resultant force acting on the implant can be decreased by increasing the installation load; however, a large installation load of 100 N should be avoided when installing the attachment on the denture base to avoid increasing the denture movement.
Atsuko Nakamichi, Takaharu Goto and Tetsuo Ichikawa : Evaluation of Eating Behavior and Mouthful Volume: Validity of YN Eating Behavior Questionnaire, Journal of Oral Health and Biosciences, Vol.27, No.2, 71-80, 2015.
(Summary)
We created a simple questionnaire to promote better eating habits and behavioral modification for the prevention and improvement of metabolic syndrome, examined its reliability and validity, and finally, assessed its effectiveness. A questionnaire, comprising of eighteen items to promote behavioral modification, was prepared comprising of three factors, "dietary recognition" , "eating habits" and "eating action" and was developed based on data from 125 students at the Faculty of Dentistry, The University of Tokushima. Furthermore, to assess the effectiveness of this version of the questionnaire, we conducted a survey on 845 health-care providers in Tokushima Prefecture and Hyogo Prefecture. The results confirmed a relatively high internal consistency with a Cronbach's alpha coefficient of 0.735–0.762 for the three factors. The questionnaire scores in the "obese" group with a body mass index of 25 or higher were high for all three factors and a significant difference was noted between the "normal" and "thin" groups under the category of "dietary awareness" . Moreover, trends between men and women; and between age groups were ascertained, therefore suggesting that this questionnaire is effective in assessing eating behavior associated with obesity.
市川 哲雄, 後藤 崇晴, Takaharu Goto, 檜垣 宣明 and 内藤 禎人 : 補綴装置および歯の延命のために(Part 6) 力のコントロール 力を受ける生体側の観点から, Annals of Japan Prosthodontic Society, Vol.7, No.4, 357--362, 2015.
58.
Nobuaki Higaki, Takaharu Goto, Yuichi Ishida, Megumi Watanabe, Yoritoki Tomotake and Tetsuo Ichikawa : Do sensation differences exist between dental implants and natural teeth?: a meta-analysis., Clinical Oral Implants Research, Vol.25, No.11, 1307-1310, 2014.
(Summary)
The purpose of this systematic review was to survey evidence pertaining to the sensation differences between natural teeth and osseointegrated dental implants. Using the MEDLINE (online PubMed) database, Cochrane Library, and Scientific Citation index, we performed a systematic search of articles. We used the following search terms: "perception or sensation and dental implant." The systematic review of the extracted articles was performed to see the sensation differences between natural teeth and dental implants. A total of six studies on oral sensation, "tactile sensibility," and "thickness discrimination" were included in the meta-analysis. As to the "tactile sensibility", all studies indicated the threshold levels of the implants were about 4-20 times higher than that of natural teeth. The tactile sensibility of an implant was significantly higher than that of a natural tooth, with an standardized mean difference (SMD) of 8.3619 (95% CI, 6.3920-10.3317) and a P < 0.0001. As to the "thickness discrimination", all studies indicated the threshold levels of implants were about 1.2-2.3 times higher than that of natural teeth. The thickness discrimination was significantly higher than that of natural teeth with an SMD of 1.2368 (95% CI, 0.8699-1.6038) and a P < 0.0001. This meta-analysis suggested that both tactile sensibility and thickness discrimination thresholds of implants were significantly higher than those of natural teeth. This meta-analysis reconfirms that sensation differences between dental implants and natural teeth exist.
Many studies on surface modifications of titanium have been performed in an attempt to accelerate osseointegration. Recently, anatase titanium dioxide has been found to act as a photocatalyst that expresses antibiotic properties and exhibits hydrophilicity after ultraviolet exposure. A blue-violet semiconductor laser (BV-LD) has been developed as near-ultraviolet light. The purpose of this study was to investigate the effects of exposure to this BV-LD on surface modifications of titanium with the goal of enhancing osteoconductive and antibacterial properties. The surfaces of pure commercial titanium were polished with #800 waterproof polishing papers and were treated with anatase titania solution. Specimens were exposed using BV-LD (λ = 405 nm) or an ultraviolet light-emitting diode (UV-LED, λ = 365 nm) at 6 mW/cm(2) for 3 h. The surface modification was evaluated physically and biologically using the following parameters or tests: surface roughness, surface temperature during exposure, X-ray diffraction (XRD) analysis, contact angle, methylene blue degradation tests, adherence of Porphyromonas gingivalis, osteoblast and fibroblast proliferation, and histological examination after implantation in rats. No significant changes were found in the surface roughness or XRD profiles after exposure. BV-LD exposure did not raise the surface temperature of titanium. The contact angle was significantly decreased, and methylene blue was significantly degraded. The number of attached P. gingivalis organisms was significantly reduced after BV-LD exposure compared to that in the no exposure group. New bone was observed around exposed specimens in the histological evaluation, and both the bone-to-specimen contact ratio and the new bone area increased significantly in exposed groups. This study suggested that exposure of titanium to BV-LD can enhance the osteoconductivity of the titanium surface and induce antibacterial properties, similar to the properties observed following exposure to UV-LED.
Kan Nagao, Takaharu Goto, Yuichi Ishida, Tetsuo Ichikawa, M Hideshima, H Koshino, K Hoshiai and Y Umekawa : Should Occlusal Pressure be Applied in Fixing Magnet Assenmlies to Denture? An Evaluation using the Delphi Technique, The Journal of the Japanese Sociaty of Magnetic Applications in Dentistry, Vol.22, No.2, 43-46, 2013.
61.
Takaharu Goto, Yuichi Ishida, Kan Nagao and Tetsuo Ichikawa : Long-term follow-up case reports on the use of magnetic attachment as intracoronal/extracoronal attachments, The Journal of the Japanese Sociaty of Magnetic Applications in Dentistry, Vol.22, No.2, 12-14, 2013.
62.
Tetsuo Ichikawa, Takaharu Goto and Yoritoki Tomotake : Stress Analysis of Magnet-Retained Mini-Implant Overdenture:InVitro Study, Journal of Japanese Society of Oral Implantology, Vol.26, No.4, 660-667, 2013.
(Summary)
The purpose of this study was to evaluate stress analysis of a magnet-retained mini-implant overdenture on an in vitro mandibular model. Mini implants less than 3.0 mm in diameter have been used as not only provisional use, but also permanent use to support overdentures.<br/>Four mini implants (MagDen Fixture MFI4010RF, Shinwon Dental, Seoul, Korea) were placed in edentulous regions between bilateral canines in an acrylic resin mandibular model and the abutments (MagDen Keeper MFK4020, Shinwon Dental, Seoul, Korea) for magnet attachments were used. Seven strain gauges were attached on the resin surface around the right side of two mini implants. The surface of the model was covered with silicone impression material to simulate oral mucosa and an experimental complete denture was placed on the model. A vertical force of 50 N was applied to either one of the premolar, first molar and second molar of the experimental denture using a universal testing machine. <br/>When four mini implants were supported, compressive strains were caused at the lingual side of the distal mini implant. The more posterior the loading point was, the lower the strain around the implant was generally. Although tensile strain was caused at the buccal side of the mesial mini implant, it decreased at the moment when compressive strain arose. When four implants were supported, the strain around the mini implants was distributed more evenly than those in the two implant-supported ones. The influence of implant positioning was examined by removing either two mesial or two distal attachments in the four mini implants. The maximum strain in two mesial implant-supported attachments was smaller than that in two distal implant-supported attachments.
(Keyword)
mini implant / stress analysis / magnetic attachment / overdenture / strain
Toshiya Kashiwabara, Takeyoshi Yoneyama, Atsuko Nakamichi, Tsuyoshi Honda, Sachie Toko, Takaharu Goto, Kan Nagao and Tetsuo Ichikawa : In Vitro Efficacy of Electrolyzed Dilute Sodium Hypochlorite Solution on Candidal Biofilm, Japanese Journal of Gerodontology, Vol.28, No.3, 277-283, 2013.
(Summary)
The effectiveness of oral care interventions for preventing aspiration pneumonia and barriers to compromised elderly is universally-recognized in present medical practice. Quick and effective methods and materials are needed for oral health care. An electrolyzed dilute sodium hypochlorite solution was chosen as a sterilizing solution for oral health care and the sterilizing effect was evaluated using an in vitro candida biofilm. Three electrolyzed functional waters, namely strongly alkaline water, weakly acidic water, dilute sodium hypochlorite solution, two kinds of commercial mouth wash and distilled water were used as test solutions. Antibiofilm efficacy and residual chlorine concentration were evaluated before/after immersing candidal biofilm specimens in each solution. pH changes of the solutions and macroscopic observations of metal surface were evaluated before/after immersing three kinds of dental metals: steel bar, cobalt-chromium alloy and gold-silver-palladium alloy in the solutions to test the corrosion behavior. An electrolyzed dilute sodium hypochlorite solution showed high bactericidal capability of candida biofilm on cell desks and stable concentration of available chlorine, but high induction of metal corrosion.
(Keyword)
electrolyzed dilute sodium hypochlorite solution / proteolytic / functional water / Candida biofilm / oral health care
Hideki Suito, Yuki Iwawaki, Takaharu Goto, Yoritoki Tomotake and Tetsuo Ichikawa : Oral factors affecting titanium elution and corrosion: an in vitro study using simulated body fluid., PLoS ONE, Vol.8, No.6, e66052, 2013.
(Summary)
Ti, which is biocompatible and resistant to corrosion, is widely used for dental implants, particularly in patients allergic to other materials. However, numerous studies have reported on Ti allergy and the in vitro corrosion of Ti. This study investigated the conditions that promote the elution of Ti ions from Ti implants. Specimens of commercially pure Ti, pure nickel, a magnetic alloy, and a gold alloy were tested. Each specimen was immersed in a simulated body fluid (SBF) whose pH value was controlled (2.0, 3.0, 5.0, 7.4, and 9.0) using either hydrochloric or lactic acid. The parameters investigated were the following: duration of immersion, pH of the SBF, contact with a dissimilar metal, and mechanical stimulus. The amounts of Ti ions eluted were measured using a polarized Zeeman atomic absorption spectrophotometer. Eluted Ti ions were detected after 24 h (pH of 2.0 and 3.0) and after 48 h (pH of 9.0). However, even after 4 weeks, eluted Ti ions were not detected in SBF solutions with pH values of 5.0 and 7.4. Ti elution was affected by immersion time, pH, acid type, mechanical stimulus, and contact with a dissimilar metal. Elution of Ti ions in a Candida albicans culture medium was observed after 72 h. Elution of Ti ions in the SBF was influenced by its pH and by crevice corrosion. The results of this study elucidate the conditions that lead to the elution of Ti ions in humans, which results in implant corrosion and Ti allergy.
Tetsuo Ichikawa, Yoritoki Tomotake and Takaharu Goto : A Literature Review on the Perception of Implants : Comparison with Natural Teeth, Journal of Japanese Society of Oral Implantology, Vol.26, No.2, 272-280, 2013.
Hideki Suito, Takaharu Goto, 岩脇 有軌, Yoritoki Tomotake and Tetsuo Ichikawa : 磁性アッタチメントを用いたミニインプラントオーバーデンチャーの力学的解析, Journal of Japanese Society of Oral Implantology, Vol.26, No.4, 660-667, 2013.
67.
Yoshihito Naitou, Ashrin N. Meinar, Yuki Iwawaki, Toshiya Kashiwabara, Takaharu Goto, Teruaki Ito, Tetsuro Sakuma and Tetsuo Ichikawa : Recording of individual identification information on dental prostheses using fluorescent material and ultraviolet light, The International Journal of Prosthodontics, Vol.26, No.2, 172-174, 2013.
(Summary)
The placement of individual identification on a prosthesis is very important for forensic dentistry and traceability. This article describes the unique naming/labeling of dentures with information for individual identification using a method in which information is invisible under natural light but visible under ultraviolet light-emitting diode/black light exposure. The use of laser beam machining with this method will enable the recording of a large amount of information.
As the connection mechanism between the superstructure and implant, the cement-retained type and screw-retained type are mainly used. The choice of a screw-retained versus a cement-retained superstructure is a complex and comprehensive decision involving many points of consideration. On the other hand, various retained methods that is complementary with each retained type have been proposed. In this article, various retained types which have been reported in the literatures and developed by us, were systematically assorted from the standpoints of retreivability, and the advantages were pointed out showing case photographs. This systematical information would help the selection of retained type of the superstructure.
Takaharu Goto, Hidenobu Nishinaka, Toshiya Kashiwabara, Kan Nagao and Tetsuo Ichikawa : Main occluding area in partially edentulous patients: changes before and after implant treatment, Journal of Oral Rehabilitation, Vol.39, No.9, 677-683, 2012.
(Summary)
The 'main occluding area', the location where food crushing occurs during the first stroke of mastication, is reported to be an important concept; however, it is currently limited to findings in individuals with normal dentition. The purpose of this study was to assess the changes in the location, area and bite force of the main occluding area before and after implant treatments. We enrolled 50 partially edentulous and 22 normally dentate subjects. To identify the location of the main occluding area, each subject was instructed to freely bite once on a dental stopping using the partially edentulous side or the normally dentate area. The location, occluding contact area and bite force of the main occluding area before and after the implant treatments were analysed. The main occluding area was located at a reproducible location in the partially edentulous and normally dentate subjects. This location was principally the first molar region, and for the partially edentulous patients with missing teeth in the molar regions, it moved from the premolar region to the first molar region after treatment. The occluding contact area and bite force for the main occluding area increased (P < 0·05) after the implant treatment in the partially edentulous patients with missing teeth in the molar regions. These results suggest that the main occluding area can be restored to the first molar region after implant treatment and may be an important factor in the assessment of prosthodontic treatment.
Atsuko Nakamichi, Takaharu Goto, 東岡 紗知江, Miwa Matsuyama and Tetsuo Ichikawa : The Survey on a General Youth's Eating Behavior, Journal of Japanese Society for Mastication Science and Health Promotion, Vol.22, No.1, 26-35, 2012.
(Keyword)
Eating behavior questionnaire / Obese / BMI / Number of chewing strokes
Jing Li, Katsuhiko Hirota, Takaharu Goto, Hiromichi Yumoto, Yoichiro Miyake and Tetsuo Ichikawa : Biofilm formation of Candida albicans on implant overdenture materials and its removal., Journal of Dentistry, Vol.40, No.8, 686-692, 2012.
(Summary)
The purposes of this study were to clarify the surface characteristics of various implant overdenture materials and the capabilities of Candida albicans adherence and biofilm formation on these surfaces, and to investigate the role of salivary mucin in biofilm formation. Seven commonly used implant and restorative materials were assessed. The surface roughness averages of all materials were limited to 0.07-0.10μm. Contact angles and salivary mucin absorption were measured. After 90-min initial adhesion and 2-day biofilm formation, the amounts of C. albicans were determined by counting colony-forming units and the morphological characteristics were observed by scanning electron microscopy (SEM). The effects of saliva coating and the influences of material surface property on initial adhesion, biofilm formation and its removability were analysed by univariate two-way analysis of variance and multiple linear regression analysis. Surface contact angle of materials, the index of hydrophobicity, was found to be correlated positively with initial adhesion and biofilm formation of C. albicans. A negative correlation between mucin absorption and removability of Candida biofilm indicates that mucin plays an important role in biofilm formation and its rigidity. SEM observation also revealed fewer Candida cells on saliva-coated Ti than on saliva-coated hydroxyapatite or acrylic resin. The materials with different hydrophobic property and compositions display diverse manners of salivary mucin absorption, initial adhesion and biofilm formation. The hydrophobic materials encourage enhanced initial adhesion, subsequently resulting in the active biofilm formation. Mucin has decisive effects on Candida immobilization and biofilm development on the materials. Surface hydrophilic property and composition of materials and salivary proteins, especially mucin, affect the process of Candida biofilm formation and influence the amount and rigidity of formed biofilm. The present data may be applied as a reference for selecting materials in implant overdenture treatment from a microbiological point of view.
楓公 士朗, Takaharu Goto, 田中 佑人, 菱川 龍樹, 藤野 智子, 前田 望, 村上 大輔, 米田 博行, Wirianski Alexander, 小嶺 裕子 and 服部 佳功 : Effects of physiotherapeutic exercise of the jaw on chewing movements in humans, The Journal of Japanese Society of Stomatognathic Function, Vol.18, No.2, 161-166, 2012.
Tetsuo Ichikawa, Kan Nagao and Takaharu Goto : Alternative Decision Making Considerations in Prosthodontics, The International Journal of Prosthodontics, Vol.25, No.3, 260-261, 2012.
Jian-Rong CHENJ, Kenji Oka, Takanori KAWANO, Takaharu Goto and Tetsuo Ichikawa : Carbon dioxide laser application enhances the effect of silane primer on the shear bone strength between porcelain and composite resin, Dental Materials Journal, Vol.29, No.6, 731-737, 2010.
(Summary)
The purpose of this study was to evaluate the effect of carbon dioxide laser irradiation on the performance of silane coupling agent as an adhesion promoter. The carbon dioxide laser used in this study was Opelaser 03S II, which irradiated the silane coupling agent applied on the adhesive surface of porcelain. Before and after thermal cycling, shear bond strength was measured using a universal testing machine. Without primer treatment, most of the specimens failed adhesively before reaching the end of the thermal cycling period. For the specimens irradiated with carbon dioxide laser after primer treatment, their shear bond strengths before and after thermal cycling were higher than those treated with primer only -with a significantly pronounced difference between these two groups especially after thermal cycling. Therefore, a combined surface treatment which involved silane application followed by laser treatment was feasible and efficacious for chairside porcelain repair.
Takahiro Kishimoto, Takaharu Goto, Takashi Matsuda, Yuki Iwawaki and Tetsuo Ichikawa : Application of artificial intelligence in the dental field: A literature review., Journal of Prosthodontic Research, Vol.66, No.1, 19-28, Jan. 2022.
(Summary)
Application of AI in the dental field has progressed; however, the criteria for evaluating the efficacy of AI have not been clarified. It is necessary to obtain better quality data for machine learning to achieve the effective diagnosis of lesions and suitable treatment planning.
Yasuhiko Shirayama, Shizuko Yanagisawa, 一ノ宮 実咲, 渡邉 彩, Yuko Takeuchi, Tetsuo Ichikawa, Takaharu Goto and 藤原 真治 : Current Status and Issues of Community-based Integrated Care System in Tokushima Prefecture -Health Survey of Koyadaira District, Mima City-, Journal of Oral Health and Biosciences, Vol.33, No.1, 24-27, Jun. 2020.
(Summary)
It is predicted that the population of Tokushima Prefecture will decrease to 550,000 by 2040, and 17 municipalities will disappear. For that reason, the community-based integrated care system (integrated care) must be further developed. The purpose of integrated care is the realization of "community development which you can continue to live as you are in the area where you are accustomed to living". To achieve this, not only medical and care, but also the utilization of new human resources and resources has been demanded. In Japan, based on the Sustainable Development Goals (SDGs), relevant laws and systems will be revised to achieve the agenda set forth by 2030, and it has been strongly suggested that it is necessary to participate the welfare area (Long-term care insurance) not only in medicine but also in dentistry.<br>In this paper, we discuss the current situation and issues of integrated care in Tokushima Prefecture, and discuss the future state in relation to the study of the Koyadaira district in Mima City, which is an area of disappearance.
(Keyword)
aging / population decline / community-based integrated care system
(Tokushima University Institutional Repository: 111853)
5.
Tetsuo Ichikawa, Takaharu Goto, 岩脇 有軌, 檜垣 宜明 and 内藤 禎人 : 力を受ける生体側の観点から(シリーズ:補綴装置および歯の延命のために Part 6 -力のコントロール-), Annals of Japan Prosthodontic Society, Vol.7, No.4, 357-362, Oct. 2015.
6.
Takaharu Goto, 岩脇 有軌, Megumi Watanabe, Kan Nagao and Tetsuo Ichikawa : Personal Identification in Dental Prostheses: A Review of the Literature, Journal of Oral Health and Biosciences, Vol.27, No.2, 21-27, Feb. 2015.
(Summary)
In disasters such as hydraulic bore, earthquakes and fire, the oral structure including the dental prostheses can provide identifying information. Over the years, many different personal identification system of dental prostheses have been reported. This present study analyzes the published literature offering the description of the personal identification system of dental prostheses.Two databases, "PubMed" and "Japana Centra Revuo Medicina" were searched to retrieve research papers referred to the personal identification system of dental prostheses. Twenty four papers were selected from the database with the criteria, and they were reviewed. This literature search showed that the personal identifications in three kinds of dental prostheses: removable denture, crown and implant were reported; and more papers on removable dentures were extracted compared to the crown and implant, however there is no high quality paper indicating that the structured methods for personal identification of dental prostheses is effective. A new method and common write format for personal identification are required to improve the present problems, and our systems using fluorescent material and ultraviolet light and femtosecond pulse laser-oriented recording system would be effective.
Takaharu Goto, Megumi Watanabe and Tetsuo Ichikawa : 問題を抱えた歯の治療計画における意思決定アルゴリズム, the Quintessence, Vol.33, No.9, 183-192, Sep. 2014.
8.
Kan Nagao, Takaharu Goto, Yuichi Ishida and Tetsuo Ichikawa : 磁性アタッチメントの診療ガイドライン策定 デルファイ法とは, The Journal of the Japanese Society of Magnetic Applications in Dentistry, Vol.21, No.1, 32-36, Dec. 2012.
Proceeding of International Conference:
1.
Takaharu Goto : Oral function assessment using digital technology: Challenges for digital transformation., Symposium of Digital & Magnet Dentistry, Oct. 2023.
2.
Ryota Nishio, Masaki Oono, Takaharu Goto, Takahiro Kishimoto and Masami Shishibori : A reconstruction method of 3D face model from front and side 2D face images using deep learning model, Proceedings Volume 11794, Fifteenth International Conference on Quality Control by Artificial Vision; 1179406 (2021), Tokushima, Jul. 2021.
Takahiro Kishimoto, Takaharu Goto and Tetsuo Ichikawa : A novel three-dimensional face modeling using photogrammetry in dental chair-side, The 6th Biennial Joint Congress of CPS-JPS-KAP (Online), Feb. 2021.
4.
Takaharu Goto, Tsukasa Hihara, Keiko Fujimoto, Kan Nagao and Tetsuo Ichikawa : Sex difference of clinical cascade from oral hypofunction to physical frailty, The 7th Biennial Joint Congress of KAP-CPS-JPS, Mar. 2019.
5.
Takahiro Kishimoto, Takaharu Goto and Tetsuo Ichikawa : Neuroscientific evaluation of periodontal tactile with/without sensory integration task: comparison between incisor and molar teeth, 11th Biennial Congress of Asian Academy of Prosthodontics, Kuala Lumpur, Malaysia, Sep. 2018.
6.
Takaharu Goto, Tsukasa Hihara, Tagami Yoshihiro, Yuki Iwawaki, Kan Nagao and Tetsuo Ichikawa : Investigation with questionnaires on symptoms of physical frailty and eating behaviors, 11th Biennial Congress of Asian Academy of Prosthodontics, Kuala Lumpur, Malaysia, Sep. 2018.
7.
Tetsuo Ichikawa, Takaharu Goto, Tsukasa Hihara, Tagami Yoshihiro and Kan Nagao : A quantitative evaluation of oral frailty-physical frailty relationship model based on covariance structure analysis, 11th Biennial Congress of Asian Academy of Prosthodontics, Kuala Lumpur, Malaysia, Sep. 2018.
8.
Takaharu Goto, Hihara Tsukasa, Kishimoto Takahiro, Takashi Matsuda, Yuki Iwawaki, Kan Nagao and Tetsuo Ichikawa : Investigation with questionnaires on symptoms of oral frailty and eating behaviors: Importance of chewing, Biennial Joint Congress of JPS-CPS-KAP, Wenzhou, China, Oct. 2017.
9.
Tetsuo Ichikawa, Higaki Nobuaki, Takaharu Goto, Kishimoto Takahiro, Yuki Iwawaki, Takashi Matsuda, Ishida Yuichi and Watanabe Megumi : A comparison of the occlusal force-sustaining ability of natural and dental implant patients during a sensory integration task, Biennial Joint Congress of JPS-CPS-KAP, Wenzhou, China, Oct. 2017.
10.
Takaharu Goto and Tetsuo Ichikawa : Frailty and Oral Frailty in super-aging society: Physiological considerations and Prosthodontic Strategy, Biennial Joint Congress of JPS-CPS-KAP, Wenzhou, China, Oct. 2017.
11.
Takashi Matsuda, Kurahashi Kosuke, Ishida Yuichi, Takaharu Goto, Kan Nagao and Tetsuo Ichikawa : Part-digitizing system for complete denture fabrication using digital impression and specialized CAD/CAM tray, The 17th Biennial Meeting of International College of Prosthodontists, Santiago, Chile, Sep. 2017.
12.
Kishimoto Takahiro, Takaharu Goto and Tetsuo Ichikawa : Differences in prefrontal activities under sensory integration task: Comparison between incisor and molar teeth, The 17th Biennial Meeting of International College of Prosthodontists, Santiago, Chile, Sep. 2017.
13.
Takaharu Goto, Hihara Tsukasa, Kishimoto Takahiro, Takashi Matsuda and Tetsuo Ichikawa : Influence of solitary eating in the elderly on symptoms on Oral frailty and Physical frailty, The 17th Biennial Meeting of International College of Prosthodontists, Santiago, Chile, Sep. 2017.
14.
Takaharu Goto : Fraitly and Oral Fraitly: Biomarker and Prosthodontic Strategy, Advanced on Seminar Digital Dentistry Joint Meeting Tokushima University Alumnae Association-Indonesia Dental Association, Lombok island, Indonesia, Jan. 2017.
15.
Takaharu Goto, Yoritoki Tomotake, Yuichi Ishida, Nobuaki Higaki, Kan Nagao and Tetsuo Ichikawa : Functional Significance of the Main Occluding Area for Partially Edentulous, 16th Biennial Meeting of International College of Prosthodontists, Sep. 2015.
16.
Nobuaki Higaki, Takaharu Goto, Yuki Iwawaki, Kan Nagao and Tetsuo Ichikawa : Brain Function on Modulation of Occlusal Force and Sensory Integration, 16th Biennial Meeting of International College of Prosthodontists, Sep. 2015.
17.
Shiori Nakamura, Nobuaki Higaki, Takaharu Goto, Kan Nagao and Tetsuo Ichikawa : Effect analysis of oral stimulation to prevent dementia focusing on the individual sensibility, 16th Biennial Meeting of International College of Prosthodontists, Sep. 2015.
18.
Takashi Matsuda, Takaharu Goto, Toshiya Kashiwabara, Kan Nagao and Tetsuo Ichikawa : Possibility of Complete Denture Fabrication using Digital Technology: the possibility of Contactless Digital Preliminary Impression, The 3rd ASEAN plus and TOKUSHIMA Joint International Conference on ``Strategic Achievement of Oral Sciences and Promotion of Quality of Life'', Makassar, Dec. 2014.
19.
Nobuaki Higaki, Takaharu Goto, Yuichi Ishida, Kan Nagao and Tetsuo Ichikawa : Effects of vibratory and gustatory stimulations on cerebral blood flows, The 3rd ASEAN plus and TOKUSHIMA Joint International Conference ``Strategic Achievement of Oral Sciences and Promotion of Quality of Life'', Makassar, Dec. 2014.
20.
Takaharu Goto, Yoritoki Tomotake, Yuichi Ishida, Nobuaki Higaki, Kan Nagao and Tetsuo Ichikawa : Clinical significance of the main occluding in prosthodontic treatment, The 3rd ASEAN plus and TOKUSHIMA Joint International Conference on ``Strategic Achievement of Oral Sciences and Promotion of Quality of Life'', Makassar, Dec. 2014.
21.
Takashi Matsuda, Tetsuo Ichikawa, Takaharu Goto, Toshiya Kashiwabara and Kan Nagao : Digital preliminary impression for complete denture fabrication, Indonesia Japan Prosthodontic Society JOINT MEETING, Bali, Oct. 2014.
22.
Kan Nagao, Takaharu Goto and Tetsuo Ichikawa : Which is better for complete denture wearers, fully balanced occlusion or lingualized occlusion, Indonesian and Japan Prosthodontic Society JOINT MEETING, Bali, Oct. 2014.
23.
Takaharu Goto, Yuichi Ishida, Megumi Watanabe, Yoritoki Tomotake, Kan Nagao and Tetsuo Ichikawa : Location of the main occluding area after implant treatment, 38th Annual Conference of The European Prosthodontic Association, Istanbul, Sep. 2014.
24.
Takaharu Goto, Atsuko Nakamichi, Sachie Toko, Tsuyoshi Honda, Kan Nagao and Tetsuo Ichikawa : Assessments of Quality of mastication: Relationship between overall eating behavior and mastication, The 15th Biennial Meeting of International College of prosthodontics, Turin, Sep. 2013.
25.
Nobuaki Higaki, Takaharu Goto, Yuki Iwawaki, Kan Nagao and Tetsuo Ichikawa : Efficiency of oral stimulations on brain function activities: Evaluations using wearable near-infrared spectroscopy, The 15th Biennial Meeting of International College of prosthodontics, Turin, Sep. 2013.
26.
Takaharu Goto, Yoritoki Tomotake and Tetsuo Ichikawa : Systematic literature review on sensation of osseointegrated implants., Programs and Abstracts of Biennial Meeting of Asian Academy of Prosthodontics., Vol.8, 137, Dec. 2012.
27.
Yoritoki Tomotake, Takaharu Goto and Tetsuo Ichikawa : The Relationship between Main Occluding Area and Prosthetic Complains in Implant Superstructure., The 8th Biennial Meeting of Asian Academy of Prosthodontics, Vol.8, 139, Chennai, Dec. 2012.
28.
Hideki Suito, Takaharu Goto, Yuki Iwawaki, Yoritoki Tomotake and Tetsuo Ichikawa : Oral factors affecting titanium elution and corrosion; in vitro study using SBF solution., ASEAN plus and TOKUSHIMA Joint International Conference"Strategic Achievement of Oral Sciences and Promotion of Quality of Life", Dec. 2012.
29.
Takaharu Goto, Nobuaki Higaki, Yoritoki Tomotake, Kan Nagao and Tetsuo Ichikawa : Sensation of osseointegrated implants: literature review and new neurophysiological approach, ASEAN plus and TOKUSHIMA Joint International Conference"Strategic Achievement of Oral Sciences and Promotion of Quality of Life", Dec. 2012.
30.
Takashi Matsuda, Takaharu Goto, Yuichi Ishida, Toshiya Kashiwabara, Kan Nagao and Tetsuo Ichikawa : A Trial of Complete Denture Fabrication using Digital Technology: in vitro Evaluation of digital impression, ASEAN plus and TOKUSHIMA Joint International Conference"Strategic Achievement of Oral Sciences and Promotion of Quality of Life", Yogyakarta, Dec. 2012.
31.
Takaharu Goto, Takashi Matsuda, Yuichi Ishida, Toshiya Kashiwabara, Kan Nagao and Tetsuo Ichikawa : Digital dentistry in complete denture fabrication, --- Feasibility study ---, International Symposium on Oral Health Education and Research, Balikpapan, Dec. 2011.
32.
Takaharu Goto, Kan Nagao, Yuichi Ishida, Yoritoki Tomotake and Tetsuo Ichikawa : Influence of Attachments On Load Transfer in Implant Overdentures: Effect Of Denture Rigidity, 14th Meeting of International College of Prosthodontists, Hawaii, Sep. 2011.
Kan Nagao, Keiko Fujimoto, Hideki Suito, Takaharu Goto, Tetsuo Ichikawa and Megumi Watanabe : 嚥下機能を考慮した全部床義歯口蓋形態の形成, 日本老年歯科医学会第34回学術大会, Jun. 2023.
13.
Takaharu Goto, Takahiro Kishimoto, Keiko Fujimoto, 田上 義弘 and Tetsuo Ichikawa : におい強度に着目した咀嚼能率，唾液分泌量関連因子の同時推定法の検討, 日本補綴歯科学会第132回学術大会, May 2023.
14.
Yuki Iwawaki, 園井 厚憲, 千葉 厚子, 半田 拓弥, 中津 晋, Takaharu Goto, Keiko Fujimoto, Takahiro Kishimoto, Takashi Matsuda, Hideki Suito, HARUNA Konishi, Kan Nagao and Tetsuo Ichikawa : Efficacy of foam type denture cleanser OC441 on partial denture cleaning, 日本補綴歯科学会第132回学術大会, May 2023.
15.
Adityakrisna Yoshi Putra Wigianto, Takaharu Goto, Yuki Iwawaki and Tetsuo Ichikawa : Germicidal efficacy of portable UV-C light against Candida albicans biofilm on PMMA and SARS-CoV-2, 日本義歯ケア学会第15回学術大会, Jan. 2023.
Adityakrisna Yoshi Putra Wigianto, Yuki Iwawaki, Takaharu Goto and Tetsuo Ichikawa : 義歯床用レジン上でのC.albicansのバイオフィルム形成に対するMPCコーティングの有効性, 日本義歯ケア学会第14回学術大会, Mar. 2022.
23.
Takaharu Goto and Tetsuo Ichikawa : 歯根膜触・圧覚の感受性が咬合力と前頭前野の活動に与える影響, 日本全身咬合学会第31回学術大会, Oct. 2021.
Sapaar Bayarmagnai, Yoshihito Naitou, Takaharu Goto, Kan Nagao and Tetsuo Ichikawa : Loss of retentive force and per,manent deformation of polyethylene terephthalate and polyster clasps retainers, 平成25年度公益社団法人日本補綴歯科学会中国・四国支部学術大会, Sep. 2013.
100.
檜垣 宜明, Takaharu Goto, Yuichi Ishida, Yoritoki Tomotake, Kan Nagao, Tetsuo Ichikawa and 多田 望 : 口腔内刺激が脳機能活動に与える影響, 平成25年度公益社団法人日本補綴歯科学会中国・四国支部学術大会, Aug. 2013.
101.
Takashi Matsuda, Takaharu Goto, Yuichi Ishida, Toshiya Kashiwabara, Kan Nagao, Tetsuo Ichikawa and Masayo Okajima : デジタル技術を用いた全部床義歯治療の効率化 ―3Dスキャナによる研究用模型と作業用模型の一致度の検討―, 平成25年度公益社団法人日本補綴歯科学会中国・四国支部学術大会, Aug. 2013.
Takaharu Goto, Yuichi Ishida, Yoritoki Tomotake, Kan Nagao and Tetsuo Ichikawa : 磁性アタッチメントを歯冠内・歯冠外アタッチメントとして用いた長期経過症例について, 第22回日本磁気歯科学会学術大会, Nov. 2012.
107.
水頭 英樹, Takaharu Goto, Yoritoki Tomotake, Tetsuo Ichikawa and 西村 良一 : チタンの溶出に影響を及ぼす因子の検討, Journal of Japanese Society of Oral Implantology, Vol.25, 292, Sep. 2012.
108.
岩脇 有軌, 西中 英伸, Takaharu Goto, Yoritoki Tomotake and Tetsuo Ichikawa : インプラント上部構造における主機能部位と補綴学的問題の関連について, Journal of Japanese Society of Oral Implantology, Vol.25, 295, Sep. 2012.
Sapaar Bayarmagnai, Yoshihito Naitou, Takaharu Goto, Kan Nagao and Tetsuo Ichikawa : Extracellular DNA of Candida albicans and its effect on biofilm formation on denture base materials, 平成24年度 (社)日本補綴歯科学会中国・四国・九州合同学術大会, Sep. 2012.
Yuichi Ishida, Hideki Suito, Takaharu Goto, Yoritoki Tomotake and Tetsuo Ichikawa : Estimation of prosthetic complications occurred in the superstructure by the provisional restoration:veneer fractures and interproximal contact loss, 第41回公益社団法人日本口腔インプラント学会・学術大会, Sep. 2011.
Development of a new method for simultaneous estimation of saliva secretion and masticatory efficiency using odor detection (Project/Area Number: 20K10037 )
The pathogenesis of metal allergy development in skin and mucous membrane (Project/Area Number: 18K09661 )
Elucidation of the relationship between brain function and occlusion- mastication-nutrition, and development of prosthodontic health management model (Project/Area Number: 18H02993 )
Development of saliva secretion test by Alchole odor-detction (STAOD) (Project/Area Number: 17K19762 )
Development and evaluation of a new oral function training method applying neuro feedback training (Project/Area Number: 17K17374 )
Development of esthetic clasp with polyetheretherketone(PEEK) (Project/Area Number: 16K11597 )
Development of a program to improve oral function maintenance and management skills among nursing home caregivers based on cognitive science (Project/Area Number: 16K11596 )
Analysis of migration factor expressed in dendritic cells during metal allergy development (Project/Area Number: 15K11161 )
Clinical approach for application the quantitative sensory estimation method in occlusal adjastment of implant treatment (Project/Area Number: 25861849 )