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Tokushima UniversityUniversity HospitalClinical DivisionDepartment of Neurosurgery, Psychiatry and AnesthesiologyNeurosurgery
Tokushima UniversityFaculty of MedicineSchool of MedicineCourse of Integrated Brain SciencesNeurosurgery
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Book / Paper

Academic Paper (Judged Full Paper):

1. Toshitaka Fujihara, Yoshifumi Mizobuchi, Kohhei Nakajima, Teruyoshi Kageji, Kazuhito Matsuzaki, KT Kitazato, Ryotaro Otsuka, Keijiro Hara, Hideo Mure, Toshiyuki Okazaki, Kazuyuki Kuwayama, Shinji Nagahiro and Yasushi Takagi :
Down-regulation of MDR1 by Ad-DKK3 via Akt/NFB pathways augments the anti-tumor effect of temozolomide in glioblastoma cells and a murine xenograft model,
Journal of Neuro-Oncology, Vol.139, No.2, 323-332, 2018.
(Tokushima University Institutional Repository: 112895,   DOI: 10.1007/s11060-018-2894-5,   PubMed: 29779087,   Elsevier: Scopus)
2. Keijiro Hara, Teruyoshi Kageji, Yoshifumi Mizobuchi, Keiko T. Kitazato, Toshiyuki Okazaki, Toshitaka Fujihara, Kohhei Nakajima, Hideo Mure, Kazuyuki Kuwayama, Tomoyo Hara and Shinji Nagahiro :
Blocking of the interaction between Wnt proteins and their co-receptors contributes to the anti-tumor effects of adenovirus-mediated DKK3 in glioblastoma,
Cancer Letters, Vol.356, 496-505, 2015.
(Tokushima University Institutional Repository: 106342,   DOI: 10.1016/j.canlet.2014.09.045,   PubMed: 25301448,   Elsevier: Scopus)
3. Toshiyuki Okazaki, Teruyoshi Kageji, Kazuyuki Kuwamura, Keiko T. Kitazato, Hideo Mure, Keijiro Hara, Ryoma Morigaki, Yoshifumi Mizobuchi, Kazuhito Matsuzaki and Shinji Nagahiro :
Up-regulation of endogenous PML induced by a combination of interferon-beta and temozolomide enhances p73/YAP-mediated apoptosis in glioblastoma,
Cancer Letters, Vol.323, No.2, 199-207, 2012.
(DOI: 10.1016/j.canlet.2012.04.013,   PubMed: 22542810)

Proceeding of International Conference:

1. Toshitaka Fujihara, Teruyoshi Kageji, Yoshifumi Mizobuchi, Keijiro Hara, Kenji Shouno, Kohhei Nakajima, Hideo Mure, Kazuyuki Kuwayama and Shinji Nagahiro :
Down-regulation of MDR1 by DKK3 attenuates chemoresistance to temozolomide, and potentiates its anti-tumor effects,
20th Annual Socientific Meeting and Education Day of the Society for Neuro-Oncology, Nov. 2015.
2. Yoshifumi Mizobuchi, T Okazaki, Teruyoshi Kageji, Kazuyuki Kuwayama, KT Kitazato, Hideo Mure, Keijiro Hara, Ryoma Morigaki, Kazuhito Matsuzaki, Kohhei Nakajima, T Fujihara and Shinji Nagahiro :
A combination of interferon-beta and temozolomide augments anti-tumor effects through p73/YAP-mediated apoptosis by PML in glioblastoma,
The 4th Quadrennial Meeting of the World Federation of Neuro-Oncology held in conjunction with the 2013 SNO Scientific Meeting and Education Day, San Francisco, Nov. 2013.
3. Keijiro Hara, Teruyoshi Kageji, Yoshifumi Mizobuchi, T Okazaki, T Fujihara, Kohhei Nakajima, Hideo Mure, Kazuyuki Kuwayama, T Hara and Shinji Nagahiro :
REIC/Dkk-3, one of Dickkopf(Dkk)family members, contributes to the anti-tumor effects in glioblastoma through regulation of both Wnt signal pathways,
The 4th Quadrennial Meeting of the World Federation of Neuro-Oncology held in conjunction with the 2013 SNO Scientific Meeting and Education Day, San Francisco, Nov. 2013.
4. Kohhei Nakajima, Keijiro Hara, Teruyoshi Kageji, Yoshifumi Mizobuchi, KT KItazato, T Fujihara, Kazuyuki Kuwayama, R Otsuka, DK Kung and Shinji Nagahiro :
Down-regulation of MDR by Ad-REIC contributes to augment the chemotherapy by temozolomide,
The 4th Quadrennial Meeting of the World Federation of Neuro-Oncology held in conjunction with the 2013 SNO Scientific Meeting and Education Day, San Francisco, Nov. 2013.

Proceeding of Domestic Conference:

1. Mai Azumi, Takeshi Miyamoto, Toshitaka Fujihara, Kohhei Nakajima, Keijiro Hara, Yoshifumi Mizobuchi and Yasushi Takagi :
特発性頭蓋内圧亢進様の症状のみで発症した小児脳腫瘍の1例,
第35回中国四国脳腫瘍研究会, Sep. 2021.
2. Keijiro Hara, Yoshifumi Mizobuchi, Mai Azumi, Kohhei Nakajima and Yasushi Takagi :
AIDS関連トキソプラズマ脳症の1例,
第91回(一社)日本脳神経外科学会中国四国支部学術集会, Apr. 2021.
3. Keijiro Hara, Kyoko Nishi, Junichiro Satomi and Shinji Nagahiro :
High flow bypassとdistal occlusionを行った中大脳動脈血栓化紡錘状動脈瘤の一例,
第76回(一社)日本脳神経外科学会中国四国支部学術集会, Dec. 2013.
4. Keijiro Hara, Yoshifumi Mizobuchi, 北里 慶子, 岡﨑 敏之, Teruyoshi Kageji, Shinji Nagahiro and 公文 裕巳 :
悪性神経膠腫におけるREIC/Dkk-3遺伝子導入によるWnt蛋白制御の意義,
第13回日本分子脳神経外科学会, Sep. 2012.
5. 岡﨑 敏之, Kazuhito Matsuzaki, Yoshifumi Mizobuchi, 北里 慶子, Teruyoshi Kageji, Keijiro Hara and Shinji Nagahiro :
膠芽腫に対するテモゾロミドとインターフェロンβ併用療法におけるPMLの役割,
徳島脳腫瘍セミナー2010, Feb. 2010.

Grants-in-Aid for Scientific Research (KAKEN Grants Database @ NII.ac.jp)