Tokushima University / Educator and Researcher Directory --- Nakao, Toshihiro

Field of Study

Subject of Study

Book / Paper

Academic Paper (Judged Full Paper):

1.	Yosuke Iwakawa, Kouzou Yoshikawa, Koichi Okamoto, Tetsuji Takayama, Takuya Tokunaga, Toshihiro Nakao, Masaaki Nishi, Chie Takasu, Hideya Kashihara, Yuuma Wada, Toshiaki Yoshimoto, Shoko Yamashita and Mitsuo Shimada : Four cases of gastric adenocarcinoma and proximal polyposis of the stomach treated by robotic total gastrectomy, Surgical Case Reports, Vol.8, No.1, 70, 2022. (Summary) Gastric adenocarcinoma and proximal polyposis of the stomach (GAPPS) is a rare disease and characterized by a unique point mutation in the promoter 1B region of the adenomatous polyposis coli (APC) gene. There are two aims in surgery for GAPPS; the first is prophylactic gastrectomy, and the second is excising concurrent cancer. We performed robotic total gastrectomy (RTG) for four cases of GAPPS. Case 1 was a woman in her 40 s whose sister had died from gastric cancer. Mutational analysis revealed mutation of APC exon 1B. We performed prophylactic gastrectomy. Case 2 was a woman in her 30 s who had a mutation of APC exon 1B, and preoperative biopsy revealed suspected adenocarcinoma. Case 3 was a woman in her 40 s who was diagnosed with gastric cancer with multiple polyps in the stomach and a mutation of APC exon 1B. Case 4 was a woman in her 20 s in whom biopsy revealed low-grade dysplasia of a raised lesion. She had a mutation in APC exon 1B. We performed RTG with D1 + lymphadenectomy in all patients, and there were no intraoperative complications. Patients with GAPPS are mainly followed regularly with repeat biopsy, and tumors are detected in an early stage. As the safety of robotic surgery for the early gastric cancer is reported, RTG is an option for these patients. This is the first report of RTG for GAPPS patients. (Link to Publication Site) ● Publication site (DOI): 10.1186/s40792-022-01425-6 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 35435526 ● Search Scopus @ Elsevier (PMID): 35435526 ● Search Scopus @ Elsevier (DOI): 10.1186/s40792-022-01425-6 (DOI: 10.1186/s40792-022-01425-6, PubMed: 35435526)
2.	Kouzou Yoshikawa, Mitsuo Shimada, Jun Higashijima, Toshihiro Nakao, Masaaki Nishi, Chie Takasu, Hideya Kashihara, Syohei Eto and Yoshimi Bando : Ki-67 and Survivin as Predictive Factors for Rectal Cancer Treated with Preoperative Chemoradiotherapy., Anticancer Research, Vol.38, No.3, 1735-1739, 2018. (Summary) To evaluate the usefulness of Ki-67 index and survivin as predictive prognostic factors for rectal cancer treated with preoperative chemoradiotherapy. The Ki-67 index and survivin expression were examined in patients with stage II/III rectal cancer (n=46) by immunohistochemistry. Patients were divided into a high-group and a low-group for the Ki-67 index, and positive and negative groups for survivin expression. Overall and disease-free survival were compared between the groups, and the correlation between Ki-67 index and survivin expression was assessed. The 5-year disease-free survival rate of the group with high Ki-67 index was significantly lower than that of the group with low Ki-67 index (53% and 88%, p=0.03), as was the 5-year overall survival rate (68% and 100%, p=0.03). Findings for survivin were not significant. Ki-67 index and survivin may be useful biomarkers for rectal cancer with preoperative CRT. (Keyword) Aged / Biomarkers, Tumor / Chemoradiotherapy / Disease-Free Survival / Female / Humans / Immunohistochemistry / Inhibitor of Apoptosis Proteins / Ki-67 Antigen / Middle Aged / Neoplasm Staging / Predictive Value of Tests / Preoperative Period / Prognosis / Rectal Neoplasms / Survivin (Link to Publication Site) ● Publication site (DOI): 10.21873/anticanres.12409 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 29491110 ● Search Scopus @ Elsevier (PMID): 29491110 ● Search Scopus @ Elsevier (DOI): 10.21873/anticanres.12409 (DOI: 10.21873/anticanres.12409, PubMed: 29491110)
3.	Toshihiro Nakao, Mitsuo Shimada, Kouzou Yoshikawa, Jun Higashijima, Takuya Tokunaga, Masaaki Nishi, Chie Takasu, Hideya Kashihara, Ichio Suzuka, Takashi Nishizaki, Hiroshi Okitsu, Toshiyuki Yagi, Hidenori Miyake, Murato Miura, Mitsutoshi Fukuyama, Daisuke Wada and Yoshiaki Bando : Propensity score-matched study of laparoscopic and open surgery for colorectal cancer in rural hospitals., Journal of Gastroenterology and Hepatology, Vol.31, No.10, 1700-1704, 2016. (Summary) Various randomized clinical studies have suggested that short- and long-term outcomes of laparoscopic surgery (LAP) for colorectal cancer are comparable with those of open surgery (OP). However, these studies were performed in high-volume hospitals. The aim of the present study was to compare the outcomes of LAP versus OP for colorectal cancer in rural hospitals. This was a multicenter retrospective propensity score-matched case-control study of patients who underwent colorectal surgery from January 2004 to April 2009 in 10 hospitals in Japan. All patients underwent curative surgery for pathologically diagnosed stage II or III colorectal cancer. The primary end point was 5-year overall survival (OS). The secondary end points were disease-free survival (DFS) and postoperative complications. In total, 319 patients who underwent LAP and 1020 patients who underwent OP were balanced to 261 pairs. There was no significant difference in the OS and DFS between two groups. The operation time was significantly shorter for OP than for LAP. Blood loss was significantly lower in LAP than in OP. There was no difference in intraoperative morbidity between the two groups. The postoperative morbidity was significantly lower in LAP than in OP. The hospital stay was significantly shorter in LAP than in OP. There was no significant difference in 90-day postoperative mortality. Laparoscopic surgery may be a feasible option for colorectal cancer in rural hospitals. (Keyword) Adult / Aged / Aged, 80 and over / Colectomy / Colorectal Neoplasms / Feasibility Studies / Female / Hospitals, Rural / Humans / Laparoscopy / Length of Stay / Male / Middle Aged / Neoplasm Grading / Neoplasm Staging / Propensity Score / Retrospective Studies / Survival Analysis / Treatment Outcome (Link to Publication Site) ● Publication site (DOI): 10.1111/jgh.13322 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 26896303 ● Summary page in Scopus @ Elsevier: 2-s2.0-85002156898 (DOI: 10.1111/jgh.13322, PubMed: 26896303, Elsevier: Scopus)
4.	Kouzou Yoshikawa, Mitsuo Shimada, Jun Higashijima, Toshihiro Nakao, Masaaki Nishi, Chie Takasu, Hideya Kashihara and Syohei Eto : Combined liver mobilization and retraction: A novel technique to obtain the optimal surgical field during laparoscopic total gastrectomy., Asian Journal of Endoscopic Surgery, Vol.9, No.2, 111-115, 2016. (Summary) During laparoscopic gastrectomy, it is important to establish a good operative field and ensure an adequate working space. The combined liver mobilization and retraction method is used to get a safe and optimal view. We retrospectively analyzed 32 consecutive patients who underwent laparoscopic total gastrectomy for gastric cancer. The patients were divided into two groups: the mobilization (+) group (n = 12) and the mobilization (-) group (n = 20). Hepatic function tests were performed in all patients. Mobilization provided a satisfactory view of the working field, especially the gastroesophageal junction and the angle of His during laparoscopic total gastrectomy, and no complications were observed during liver retraction. On postoperative hepatic function testing, there was no significant difference between the two groups on any day. Combined liver mobilization and retraction may be helpful in laparoscopic total gastrectomy. (Keyword) Adult / Aged / Dissection / Female / Gastrectomy / Humans / Laparoscopy / Liver / Liver Function Tests / Male / Middle Aged / Retrospective Studies / Stomach Neoplasms (Link to Publication Site) ● Publication site (DOI): 10.1111/ases.12271 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 26679094 ● Summary page in Scopus @ Elsevier: 2-s2.0-85016924826 (DOI: 10.1111/ases.12271, PubMed: 26679094, Elsevier: Scopus)
5.	Kouzou Yoshikawa, Mitsuo Shimada, Jun Higashijima, Toshihiro Nakao, Masaaki Nishi and Hideya Kashihara : 手術手技合併症から学ぶ腹腔鏡下胃全摘出術R-Y再建の工夫, Operation, Vol.69, No.13, 1821-1825, 2015. (Keyword) 和文論文 (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1521980705650664448 (CiNii: 1521980705650664448)
6.	Toshihiro Nakao, Takashi Iwata, Masanori Hotchi, Kouzou Yoshikawa, Jun Higashijima, Masaaki Nishi, Chie Takasu, Shohei Eto, Hiroki Teraoku and Mitsuo Shimada : Prediction of response to preoperative chemoradiotherapy and establishment of individualized therapy in advanced rectal cancer., Oncology Reports, Vol.34, No.4, 1961-1967, 2015. (Summary) Preoperative chemoradiotherapy (CRT) has become the standard treatment for patients with locally advanced rectal cancer. However, no specific biomarker has been identified to predict a response to preoperative CRT. The aim of the present study was to assess the gene expression patterns of patients with advanced rectal cancer to predict their responses to preoperative CRT. Fifty-nine rectal cancer patients were subjected to preoperative CRT. Patients were randomly assigned to receive CRT with tegafur/gimeracil/oteracil (S-1 group, n=30) or tegafur-uracil (UFT group, n=29). Gene expression changes were studied with cDNA and miRNA microarray. The association between gene expression and response to CRT was evaluated. cDNA microarray showed that 184 genes were significantly differentially expressed between the responders and the non-responders in the S-1 group. Comparatively, 193 genes were significantly differentially expressed in the responders in the UFT group. TBX18 upregulation was common to both groups whereas BTNL8, LOC375010, ADH1B, HRASLS2, LOC284232, GCNT3 and ALDH1A2 were significantly differentially lower in both groups when compared with the non-responders. Using miRNA microarray, we found that 7 and 16 genes were significantly differentially expressed between the responders and non-responders in the S-1 and UFT groups, respectively. miR-223 was significantly higher in the responders in the S-1 group and tended to be higher in the responders in the UFT group. The present study identified several genes likely to be useful for establishing individualized therapies for patients with rectal cancer. (Keyword) 欧文論文 (Link to Publication Site) ● Publication site (DOI): 10.3892/or.2015.4196 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 26260776 ● Search Scopus @ Elsevier (PMID): 26260776 ● Search Scopus @ Elsevier (DOI): 10.3892/or.2015.4196 (DOI: 10.3892/or.2015.4196, PubMed: 26260776)
7.	Shohei Eto, Kouzou Yoshikawa, Mitsuo Shimada, Jun Higashijima, Takuya Tokunaga, Toshihiro Nakao, Masaaki Nishi, Chie Takasu, Horohiko Sato and Nobuhiro Kurita : The relationship of CD133, histone deacetylase 1 and thrombospondin-1 in gastric cancer., Anticancer Research, Vol.35, No.4, 2071-2076, 2015. (Summary) Gastric cancer is one of the most common types of cancer. Cancer stem cells (CSCs) have been reported to play important roles in multiple cancer types. This study investigated the correlation between cluster of differentiation 133 (CD133), histone deacetylase 1 (HDAC1) and thrombospondin-1 (THBS1) expression in advanced gastric cancer. The study included 65 patients with gastric cancer with recurrence after surgery. Expression of CD133, HDAC1 and THBS1 was examined by immunohistochemistry. Prognostic factors were investigated by multivariate analysis using Cox's proportional hazard model. Clinicopathological variables, including survival, of patients positive for CD133 expression (n=6, 23%), were compared with those without CD133 expression (n=20, 77%). Positive HDAC1 expression and THBS1 expression were observed in 34 (52%) and 17 (26%) patients, respectively. Using univariate analysis, positive expression of CD133 and negative expression of THBS1 predicted significantly worse prognosis. Multivariate analysis revealed CD133-positive and THBS1-negative expression were independent prognostic indicators. CD133 expression and THBS1 expression were prognostic factors, and a negative relationship between HDAC and THBS1 was observed in advanced gastric cancer. These biomarkers may help determine postoperative treatment in patients with gastric cancer. (Keyword) 欧文論文 / Aged / Aged, 80 and over / Antigens, CD / Biomarkers, Tumor / Female / Gene Expression Regulation, Neoplastic / Glycoproteins / Histone Deacetylase 1 / Humans / Kaplan-Meier Estimate / Male / Middle Aged / Neoplasm Recurrence, Local / Neoplastic Stem Cells / Peptides / Prognosis / Stomach Neoplasms / Thrombospondin 1 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 25862862 ● Search Scopus @ Elsevier (PMID): 25862862 (PubMed: 25862862)
8.	Chie Takasu, Mami Kanamoto, 松本規子, Takashi Iwata, Kouzou Yoshikawa, Jun Higashijima, Toshihiro Nakao, Masaaki Nishi, 江藤祥平 and Mitsuo Shimada : 外科の立場からのキャリアアップ支援, Journal of Japanese College of Surgeons, Vol.40, No.2, 170-173, 2015. (Keyword) 和文論文 (Link to Publication Site) ● Publication site (DOI): 10.4030/jjcs.40.170 (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1390001204344302080 ● Search Scopus @ Elsevier (DOI): 10.4030/jjcs.40.170 (DOI: 10.4030/jjcs.40.170, CiNii: 1390001204344302080)
9.	Jun Higashijima, Mitsuo Shimada, Takashi Iwata, Kouzou Yoshikawa, Toshihiro Nakao, Masaaki Nishi, Hideya Kashihara and Chie Takasu : New ports placement in laparoscopic central lymph nodes dissection with left colic artery preservation for sigmoid colon and rectal cancer., The Journal of Medical Investigation : JMI, Vol.62, No.3-4, 223-227, 2015. (Summary) Lymph nodes (LNs) dissection around inferior mesenteric artery (IMA) with left colic artery (LCA) preservation is difficult due to the anatomical feature of IMA. The aim of this study is to evaluate the usefulness of new ports placement inserted from a suprapubic region in laparoscopic LNs dissection around IMA with LCA preservation for sigmoid colon and ractal cancer. Twenty-two patients who underwent laparoscopic colectomy for sigmoid colon and recal cancer were included. The new ports placement group (n=15, new group) was compared with the basic ports placement group (n=7, basic group). Average number of harvested LNs, total operation time, central LNs dissection time, intraoperative blood loss were compared. There was no significant difference in the average number of harvested LNs. The mean of intraoperative blood loss of new group was significantly lower than that of the basic group (40.0±39.8 ml vs 95.7±81.0 ml, p<0.05). In addition, the mean of operation time of the new group was significantly shorter than that of the basic group (250.0±55.7 min vs 353.4±80.2 min, p<0.05). The new ports placement is useful in laparoscopic LNs dissection around IMA with LCA preservation for sigmoid colon and rectal cancer. (Keyword) 欧文論文 (Tokushima University Institutional Repository) ● Metadata: 2004470 (Link to Publication Site) ● Publication site (DOI): 10.2152/jmi.62.223 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 26399352 ● Search Scopus @ Elsevier (PMID): 26399352 ● Search Scopus @ Elsevier (DOI): 10.2152/jmi.62.223 (Tokushima University Institutional Repository: 2004470, DOI: 10.2152/jmi.62.223, PubMed: 26399352)

Academic Paper (Unrefereed Paper):

1.	Toshihiro Nakao, Mitsuo Shimada, Takuya Tokunaga, Masaaki Nishi, Hideya Kashihara, Chie Takasu, Yuuma Wada and Toshiaki Yoshimoto : Feasibility of robot-assisted surgery for defining circumferential resection margins for rectal cancer: a retrospective study., World Journal of Surgical Oncology, Vol.22, No.1, 310, 2024. (Summary) Local recurrence is a major problem after surgery for rectal cancer. Precision of the circumferential resection margin (CRM) has been shown to be an independent predictor of local recurrence. The purpose of this study is to evaluate the usefulness of robotic surgery for defining the CRM. A retrospective cohort study of patients with rectal cancer who underwent radical surgery at Tokushima University Hospital from January 2012 to April 2023 was included in this study to evaluate risk factors for CRM involvement. Short-term outcomes, including CRM rates, as well as long-term outcomes, were compared between patients who had undergone robot-assisted versus laparoscopic surgery following propensity score analysis. A total of 223 patients were analyzed in this study. Multivariate analysis demonstrated that lymph node metastasis was the most significant predictive factor for CRM involvement (p = 0.030), and that robot-assisted surgery tended to lead to less CRM involvement (p = 0.085). The CRM involvement rate for robotic and laparoscopic surgery before propensity score matching was 4.7% and 11.7%, respectively. Following propensity score matching, the CRM involvement rate for robotic surgery was 4.5% versus 11.4% for laparoscopic surgery. Disease-free survival (DFS) and overall survival (OS) rates for patients who had undergone robot-assisted and laparoscopic surgery were not significantly different before or after matching (DFS before matching: p = 0.876, DFS after matching: p = 0.805, OS before matching: p = 0.511, OS after matching: p = 0.458). Robot-assisted surgery may be useful in defining the CRM for rectal cancer. (Keyword) Humans / Rectal Neoplasms / Retrospective Studies / Male / Robotic Surgical Procedures / Female / Margins of Excision / Feasibility Studies / Aged / Laparoscopy / Middle Aged / Survival Rate / Neoplasm Recurrence, Local / Follow-Up Studies / Prognosis / Propensity Score / Lymphatic Metastasis / Adult / Aged, 80 and over (Link to Publication Site) ● Publication site (DOI): 10.1186/s12957-024-03591-3 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 39578830 ● Search Scopus @ Elsevier (PMID): 39578830 ● Search Scopus @ Elsevier (DOI): 10.1186/s12957-024-03591-3 (DOI: 10.1186/s12957-024-03591-3, PubMed: 39578830)
2.	Takayuki Noma, Masaaki Nishi, Chie Takasu, Yuuma Wada, Kozo Yoshikawa, Takuya Tokunaga, Toshihiro Nakao, Hideya Kashihara, Toshiaki Yoshimoto, Yuko Miyakami, Kengo Atsumi, Hisanori Uehara and Mitsuo Shimada : Conversion surgery after successful response to chemotherapy (S-1 + oxaliplatin + nivolumab) in a patient with stage IV gastric cancer with peritoneal metastasis (P1, CY1): a case report., International Cancer Conference Journal, Vol.13, No.1, 11-16, 2023. (Summary) We here present a case report of a patient with Stage IV gastric cancer with peritoneal metastasis (P1, CY1) who underwent conversion surgery after a successful response to chemotherapy (S-1 + oxaliplatin + nivolumab). The patient was a woman in her 60 s. Her chief complaint was epigastric pain. Upper gastrointestinal endoscopy showed Type 4 advanced carcinoma on the lesser curvature of the gastric body. Biopsy showed Group 5 (poorly differentiated adenocarcinoma) and HER2 was negative. Staging laparoscopy revealed seeding in the round ligament of the liver (P1) and adenocarcinoma cells in ascites (CY1). Ten courses of chemotherapy (S-1 + oxaliplatin + nivolumab) were administered, after which contrast-enhanced computed tomography showed that the primary tumor had shrunk and seeding was no longer detectable. Upper gastrointestinal endoscopy revealed scar-like changes. A second staging laparoscopy revealed that ascites cytology was negative and a biopsy of the round ligament of the liver showed no malignant cells (P0, CY0). Conversion surgery comprising laparoscopic total gastrectomy with D2 lymph node dissection and resection of the round ligament of the liver was performed. The postoperative course was uneventful. Histopathological examination of the resected specimen revealed no tumor cells in the gastric mesentery or the round ligament of the liver. The pathological diagnosis was gastric cancer [M, U, L, Less, Ant, Post, type4, T3(SS), N0, M0 (H0, P0, CY0), ypStage IIA]. Adjuvant chemotherapy (S-1) was commenced. The patient is still alive 7 months later with no evidence of recurrence. (Link to Publication Site) ● Publication site (DOI): 10.1007/s13691-023-00628-4 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 38187176 ● Search Scopus @ Elsevier (PMID): 38187176 ● Search Scopus @ Elsevier (DOI): 10.1007/s13691-023-00628-4 (DOI: 10.1007/s13691-023-00628-4, PubMed: 38187176)
3.	Toshihiro Nakao, Mitsuo Shimada, Kouzou Yoshikawa, Takuya Tokunaga, Masaaki Nishi, Hideya Kashihara, Chie Takasu, Yuuma Wada and Toshiaki Yoshimoto : Visualization of the pelvic nerves using magnetic resonance imaging for rectal cancer surgery., Surgical Endoscopy, Vol.37, No.6, 4315-4320, 2023. (Summary) This study evaluated the visualization of the pelvic nerves using magnetic resonance imaging (MRI) combined with computed tomography (CT) to synthesize three-dimensional (3D) reconstruction images of the pelvic organs. The CT and MRI scans were performed for patients with rectal cancer who underwent surgery. The out-of-phase image of LAVA-Flex was used to identify the pelvic nerves. The images of the pelvic nerves were extracted from the MRI scans, and those of the arteries and rectum and pelvis were extracted from the CT scans. Each extracted organ image was used to synthesize 3D reconstruction images. The MRI scan allowed adequate visualization of the pelvic splanchnic nerves, inferior hypogastric plexus, and obturator nerves. The comparison of 3D reconstruction images and intraoperative findings showed matched images. We visualized the pelvic nerves using MRI and synthesized 3D reconstruction images of the pelvic organs. Preoperative confirmation of the location of the pelvic organs is important to prevent unanticipated injury during rectal cancer surgery. (Link to Publication Site) ● Publication site (DOI): 10.1007/s00464-022-09771-0 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 36418640 ● Search Scopus @ Elsevier (PMID): 36418640 ● Search Scopus @ Elsevier (DOI): 10.1007/s00464-022-09771-0 (DOI: 10.1007/s00464-022-09771-0, PubMed: 36418640)
4.	Masaaki Nishi, Yuuma Wada, Kouzou Yoshikawa, Chie Takasu, Takuya Tokunaga, Toshihiro Nakao, Hideya Kashihara, Toshiaki Yoshimoto and Mitsuo Shimada : Utility of robotic surgery for Siewert type II/III adenocarcinoma of esophagogastric junction: transhiatal robotic versus laparoscopic approach., BMC Surgery, Vol.23, No.1, 128, 2023. (Summary) Robotic surgery (RS) has been rapidly adopted for gastric cancer and adenocarcinoma of the esophagogastric junction (AEG). However, the utility of RS for Siewert type II/III AEG remains unclear. Forty-one patients who underwent either transhiatal RS (n = 15) or laparoscopic surgery (LS) (n = 26) for Siewert type II/III AEG were enrolled in this study. The surgical outcomes of the two groups were compared. In the entire cohort, there were no significant intergroup differences in the operative time, blood loss volume, or number of retrieved lymph nodes. The length of the postoperative hospital stay was shorter in the RS group than in the LS group (14.20 ± 7.10 days vs. 18.73 ± 17.82 days, respectively; p = 0.0388). The morbidity rate (Clavien-Dindo grade ≥ 2) was similar between the groups. In the Siewert II cohort, there were no significant intergroup differences in short-term outcomes. In the entire cohort, there was no significant difference between the RS and LS groups in the 3-year overall survival rate (91.67% vs. 91.48%, N.S.) or 3-year disease-free survival rate (91.67% vs. 91.78%, N.S.), respectively. Likewise, in the Siewert type II cohort, there was no significant difference between the RS and LS groups in the 3-year overall survival rate (80.00% vs. 93.33%, N.S.) or 3-year disease-free survival rate (80.00% vs. 94.12%, N.S.), respectively. Transhiatal RS for Siewert II/III AEG was safe and contributed to similar short-term and long-term outcomes compared with LS. (Keyword) Humans / Robotic Surgical Procedures / Retrospective Studies / Gastrectomy / Adenocarcinoma / Stomach Neoplasms / Laparoscopy / Esophagogastric Junction / Esophageal Neoplasms (Tokushima University Institutional Repository) ● Metadata: 2000167 (Link to Publication Site) ● Publication site (DOI): 10.1186/s12893-023-02045-z (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 37194030 ● Search Scopus @ Elsevier (PMID): 37194030 ● Search Scopus @ Elsevier (DOI): 10.1186/s12893-023-02045-z (Tokushima University Institutional Repository: 2000167, DOI: 10.1186/s12893-023-02045-z, PubMed: 37194030)
5.	Kouzou Yoshikawa, Mitsuo Shimada, Takuya Tokunaga, Toshihiro Nakao, Masaaki Nishi, Chie Takasu, Hideya Kashihara, Yuuma Wada and Toshiaki Yoshimoto : The application of enhanced recovery after surgery in total gastrectomy: a propensity score-matched analysis., World Journal of Surgical Oncology, Vol.21, No.1, 148, 2023. (Summary) This study aimed to investigate the feasibility and safety of our enhanced recovery after surgery protocol including early oral intake and omitting nasogastric tube (NGT) placement after total gastrectomy. We analyzed 182 consecutive patients who underwent total gastrectomy. The clinical pathway was changed in 2015, and patients were divided into 2 groups (conventional group and modified group). Postoperative complications, bowel movement, and postoperative hospital stays were compared in the two groups in all cases and propensity score matching (PSM). Flatus and defecation were significantly earlier in the modified group compared with those in the conventional group (flatus: 2 (1-5) days vs 3 (2-12) days, p = 0.03; defecation: 4 (1-14) days vs 6 (2-12) days p = 0.04). The postoperative hospital stay was 18 (6-90) days in the conventional group and 14 (7-74) days in the modified group (p = 0.009). Days until discharge criteria were met were earlier in the modified group compared with that in the conventional group (10 (7-69) days vs 14 (6-84) days p = 0.01). Overall and severe complications occurred in nine patients (12.6%) and three patients (4.2%) in the conventional group and twelve patients (10.8%) and four patients (3.6%) in the modified group, respectively (p = 0.70 and p = 0.83) in all cases. In PSM, there is no significant difference between the two groups concerning the postoperative complications (overall complication 6 (12.5%) vs 8 (16.7%) p = 0.56, severe complications 1 (2%) vs 2 (4.2%) p = 0.83). Modified ERAS for total gastrectomy may be feasible and safe. (Keyword) Humans / Enhanced Recovery After Surgery / Propensity Score / Flatulence / Stomach Neoplasms / Retrospective Studies / Gastrectomy / Length of Stay / Postoperative Complications / Treatment Outcome / Laparoscopy (Link to Publication Site) ● Publication site (DOI): 10.1186/s12957-023-03034-5 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 37194033 ● Search Scopus @ Elsevier (PMID): 37194033 ● Search Scopus @ Elsevier (DOI): 10.1186/s12957-023-03034-5 (DOI: 10.1186/s12957-023-03034-5, PubMed: 37194033)
6.	Toshiaki Yoshimoto, Kouzou Yoshikawa, Toshihiro Nakao, Takuya Tokunaga, Masaaki Nishi, Chie Takasu, Hideya Kashihara, Yuuma Wada, Takayuki Noma and Mitsuo Shimada : Surgical Outcomes of Gastrectomy in Hemodialysis Patients with Gastric Cancer., The American Surgeon, Vol.89, No.12, 6328-6330, 2023. (Keyword) Humans / Stomach Neoplasms / Retrospective Studies / Laparoscopy / Gastrectomy / Treatment Outcome / Renal Dialysis (Link to Publication Site) ● Publication site (DOI): 10.1177/00031348231173970 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 37132264 ● Search Scopus @ Elsevier (PMID): 37132264 ● Search Scopus @ Elsevier (DOI): 10.1177/00031348231173970 (DOI: 10.1177/00031348231173970, PubMed: 37132264)
7.	Takuya Tokunaga, Maki Sugimoto, Yu Saitou, Hideya Kashihara, Kouzou Yoshikawa, Toshihiro Nakao, Masaaki Nishi, Chie Takasu, Yuuma Wada, Yuhei Waki, Toshiaki Yoshimoto, Takayuki Noma and Mitsuo Shimada : Transanal lateral lymph node dissection with intraoperative hologram support in low rectal cancer., Surgical Endoscopy, Vol.37, No.7, 5414-5420, 2023. (Summary) In Japan, the standard treatment for stage II/III advanced low rectal cancer is total mesorectal excision plus lateral lymph node dissection (LLND). There are also recent reports on the use of transanal LLND. However, the transanal anatomy is difficult to understand, and additional support tools are required to improve the surgical safety. The present study examined the utility of holograms with mixed reality as an intraoperative support tool for assessing the complex pelvic anatomy. Polygon (stereolithography) files of patients' pelvic organs were created and exported from the SYNAPSE VINCENT imaging system and uploaded into the Holoeyes MD virtual reality software. Three-dimensional images were automatically converted into patient-specific holograms. Each hologram was then installed into a head mount display (HoloLens2), and the surgeons and assistants wore the HoloLens2 when they performed transanal LLND. Twelve digestive surgeons with prior practice in hologram manipulation evaluated the utility of the intraoperative hologram support by means of a questionnaire. Intraoperative hologram support improved the surgical understanding of the lateral lymph node region anatomy. In the questionnaire, 75% of the surgeons answered that the hologram accurately reflected the anatomy, and 92% of the surgeons answered that the anatomy was better understood by simulating the hologram intraoperatively than preoperatively. Moreover, 92% of the surgeons agreed that intraoperative holograms were a useful support tool for improving the surgical safety. Intraoperative hologram support improved the surgical understanding of the pelvic anatomy for transanal LLND. Intraoperative holograms may represent a next-generation surgical tool for transanal LLND. (Keyword) Humans / Treatment Outcome / Lymph Node Excision / Lymph Nodes / Rectal Neoplasms / Dissection (Link to Publication Site) ● Publication site (DOI): 10.1007/s00464-023-09977-w (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 37017769 ● Search Scopus @ Elsevier (PMID): 37017769 ● Search Scopus @ Elsevier (DOI): 10.1007/s00464-023-09977-w (DOI: 10.1007/s00464-023-09977-w, PubMed: 37017769)
8.	Kouzou Yoshikawa, Mitsuo Shimada, Takuya Tokunaga, Toshihiro Nakao, Masaaki Nishi, Chie Takasu, Hideya Kashihara, Yuuma Wada and Toshiaki Yoshimoto : Stapler insertion angle toward the esophagus reduces the incidence of early postoperative Roux stasis syndrome after distal gastrectomy in minimally invasive surgery., BMC Surgery, Vol.23, No.1, 54, 2023. (Summary) Roux stasis syndrome (RSS) after Roux-en-Y (RY) reconstruction significantly prolongs the hospital stay and decreases the quality of life. The purpose of the present study was to evaluate the incidence of RSS in patients who underwent distal gastrectomy for gastric cancer and to identify the factors related to the development of RSS after mechanical RY reconstruction in minimally invasive surgery (MIS). This study included 134 patients who underwent distal gastrectomy in MIS with mechanical RY anastomosis. RSS was defined as the presence of symptoms such as nausea, vomiting, or abdominal fullness, and the confirmation of delayed gastric emptying on imaging or gastrointestinal fiber testing. Clinical data were checked, including body mass index, operative procedure, age, sex, operative time, blood loss volume, extent of lymph node dissection, final stage, stapler insertion angle, method of entry hole closure. The relationship between the incidence of RSS and these factors was analyzed. RSS occurred in 24 of 134 patients (17.9%). RSS occurred significantly more frequently in patients with D2 lymphadenectomy than in patients with D1 + lymphadenectomy (p = 0.04). All patients underwent side-to-side anastomosis via the antecolic route. The incidence of RSS was significantly greater in patients with a stapler insertion angle toward the greater curvature (n = 20, 22.5%) versus the esophagus (n = 4, 8.9%) (p = 0.04). The multivariate logistic regression model revealed that the stapler insertion angle to the greater curvature is identified as independent risk factor for RSS (OR 3.23, 95%Cl 1.01-10.3, p = 0.04). Stapler insertion angle toward the esophagus may reduce the incidence of early postoperative RSS rather than toward the greater curvature. (Keyword) Humans / Incidence / Quality of Life / Gastrectomy / Anastomosis, Roux-en-Y / Esophagus / Stomach Neoplasms / Minimally Invasive Surgical Procedures / Postoperative Complications (Tokushima University Institutional Repository) ● Metadata: 2011614 (Link to Publication Site) ● Publication site (DOI): 10.1186/s12893-023-01954-3 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 36906525 ● Search Scopus @ Elsevier (PMID): 36906525 ● Search Scopus @ Elsevier (DOI): 10.1186/s12893-023-01954-3 (Tokushima University Institutional Repository: 2011614, DOI: 10.1186/s12893-023-01954-3, PubMed: 36906525)
9.	Hideya Kashihara, Mitsuo Shimada, Kouzou Yoshikawa, Takuya Tokunaga, Toshihiro Nakao, Masaaki Nishi, Chie Takasu, Yuuma Wada and Toshiaki Yoshimoto : The Impact of the Pre-operative Neutrophil-lymphocyte Ratio as the Predictive Marker of Post-operative Weight Loss and Improving Diabetes in Sleeve Gastrectomy., The Journal of Medical Investigation : JMI, Vol.70, No.1.2, 140-144, 2023. (Summary) The aim was to investigate the impact of the neutrophil-lymphocyte ratio (NLR) in sleeve gastrectomy (SG). 15 obese patients were enrolled in this study ; mean body weight (BW) 127.5kg ; mean body mass index (BMI) 46.7kg/m. 10 of these were diabetics who underwent a SG. The impact of the pre-operative NLR on the percentage of excess weight loss (%EWL) and remission of diabetes 1 year post-operative were examined. The %EWL at 1 year post-operative were 46.3%. Improvements were also evident in the diabetes at 1 year post-operative : complete remission (CR) 40%, partial remission (PR) 20% and Improve 40%. Comparing pre-operative NLR in %EWL<50% and ≧50% in 1 year post-operative, <50% was 2.64 and ≧50% was 2.03. The NLR in CR and PR was significantly lower than that in Improve. The pre-operative NLR may be a predictive marker of weight loss and improving diabetes after SG. J. Med. Invest. 70 : 140-144, February, 2023. (Keyword) Humans / Obesity, Morbid / Treatment Outcome / Neutrophils / Retrospective Studies / Laparoscopy / Diabetes Mellitus / Weight Loss / Body Mass Index / Gastrectomy (Link to Publication Site) ● Publication site (DOI): 10.2152/jmi.70.140 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 37164710 ● Search Scopus @ Elsevier (PMID): 37164710 ● Search Scopus @ Elsevier (DOI): 10.2152/jmi.70.140 (DOI: 10.2152/jmi.70.140, PubMed: 37164710)
10.	Masaaki Nishi, Yuuma Wada, Kouzou Yoshikawa, Chie Takasu, Takuya Tokunaga, Toshihiro Nakao, Hideya Kashihara, Shin-ichiro Yamada, Toshiaki Yoshimoto and Mitsuo Shimada : Prognostic impact of frailty after gastrectomy in elderly gastric cancer patients., The Journal of Medical Investigation : JMI, Vol.70, No.3.4, 423-429, 2023. (Summary) Frailty plays a crucial role in cancer patients who have received surgery in this recent aging society. We aimed to investigate frailty as a prognostic factor in elderly gastric cancer (GC) patients who underwent curative gastrectomy. We analyzed 86 elderly (over 75 years old) GC patients who underwent curative gastrectomy. Patients were assigned to two groups;frailty group (n=29) and no-frailty group (n=57). Clinicopathological values were compared between the two groups. The OS rate of the frailty group was significantly poorer than that of the no-frailty group (5-yr OS rate;frailty group 52.49% vs. no-frailty group 74.87%, p<0.05). Multivariate analysis of the OS showed that frailty tended to be significant prognostic factor (p=0.09). The DFS rate of the frailty group was significantly poorer than that of the no-frailty group (5-yr DFS rate;frailty group 42.30% vs. no-frailty group 71.55%, p<0.05). Multivariate analysis of the DFS showed that frailty tended to be significant prognostic factor (p=0.14). We identified the clinical impact of frailty prognostic factor for elderly GC patients who underwent gastrectomy. J. Med. Invest. 70 : 423-429, August, 2023. (Keyword) Humans / Aged / Prognosis / Stomach Neoplasms / Frailty / Aging / Gastrectomy / Retrospective Studies (Link to Publication Site) ● Publication site (DOI): 10.2152/jmi.70.423 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 37940527 ● Search Scopus @ Elsevier (PMID): 37940527 ● Search Scopus @ Elsevier (DOI): 10.2152/jmi.70.423 (DOI: 10.2152/jmi.70.423, PubMed: 37940527)
11.	Chie Takasu, Masaaki Nishi, Kouzou Yoshikawa, Takuya Tokunaga, Toshihiro Nakao, Hideya Kashihara, Yuuma Wada, Toshiaki Yoshimoto, Shohei Okikawa, Shoko Yamashita and Mitsuo Shimada : Role of IDO expression in patients with locally advanced rectal cancer treated with preoperative chemoradiotherapy., BMC Cancer, Vol.22, No.1, 1263, 2022. (Summary) The role of the immune system in locally advanced rectal cancer (LARC) following preoperative chemoradiotherapy (CRT) has been widely investigated in recent years. This study examined the prognostic significance of indoleamine-pyrrole 2,3-dioxygenase (IDO) expression in patients with LARC who received preoperative CRT. Ninety patients with LARC who underwent preoperative CRT and curative resection were enrolled. IDO and programmed death-ligand 1 (PD-L1) expression was evaluated by immunohistochemistry. Clinicopathological factors did not significantly differ between patients with positive or negative IDO expression, excluding the correlation of positive IDO expression with better tumor differentiation (p = 0.02). IDO expression was not associated with pathological response (p = 0.44), but it was associated with PD-L1 expression. The 5-year overall survival (OS) rate was significantly worse in the IDO-positive group than in the IDO-negative group (64.8% vs. 85.4%, p = 0.02). Univariate analysis identified IDO and PD-L1 expression (p = 0.02), surgical procedure (p = 0.01), final pathological stage (p = 0.003), lymph node metastasis (p < 0.001), and lymphatic invasion (p = 0.002) as significant prognostic factors for OS. Multivariate analysis revealed that IDO expression (HR: 7.10, p = 0.0006), surgical procedure (HR: 5.03, p = 0.01), lymph node metastasis (HR: 2.37, p = 0.04) and lymphatic invasion (HR: 4.97, p = 0.01) were independent prognostic indicators. Disease-free survival was not correlated with IDO or PD-L1 expression. IDO expression in patients with LARC who received preoperative CRT could be a potential prognostic indicator. IDO expression could be a useful marker for specifying individual treatment strategies in LARC. (Keyword) Humans / B7-H1 Antigen / Chemoradiotherapy / Lymphatic Metastasis / Neoadjuvant Therapy / Prognosis / Rectal Neoplasms / Indoleamine-Pyrrole 2,3,-Dioxygenase (Tokushima University Institutional Repository) ● Metadata: 2010792 (Link to Publication Site) ● Publication site (DOI): 10.1186/s12885-022-10357-1 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 36471264 ● Search Scopus @ Elsevier (PMID): 36471264 ● Search Scopus @ Elsevier (DOI): 10.1186/s12885-022-10357-1 (Tokushima University Institutional Repository: 2010792, DOI: 10.1186/s12885-022-10357-1, PubMed: 36471264)
12.	Chie Takasu, 調憲, Kouzou Yoshikawa, Takuya Tokunaga, Toshihiro Nakao, Masaaki Nishi, Hideya Kashihara, Yuuma Wada, Toshiaki Yoshimoto and Mitsuo Shimada : オンライン時代は女性医師キャリア形成の追い風となる, The Japanese Journal of Gastroenterological Surgery, Vol.55, No.11, 729-732, 2022. (Summary) 新型コロナウイルス感染症の拡大が,これまで停滞していた医師の働き方改革の推進へとつながっている.その中でも,学会のオンライン化は医師の働き方に大きな変化をもたらした.学会のリモート参加は,自宅に居ながら参加でき,地方からも参加しやすく,移動時間と費用の大きな削減となる.オンデマンド配信は,時間・場所にかかわらず学ぶ機会を得られる非常に有効なツールとなる.また,学会の委員活動など,習慣的に行われていた対面での会議が,現在はほぼ遠隔で行われている.これまで時間的制約により,積極的に学会活動に手を挙げることができなかった女性医師の同分野での活躍推進が期待される.特に子育て中の女性医師にとって,オンライン化はワーク・ライフ・バランスを維持しながらキャリアを形成していく有効なツールとなりうる.この変化を逃さず女性活躍推進へとつなげるための,オンライン学会(ハイブリット形式)の継続を強く要望したい.(著者抄録) (Keyword) 育児労働衛生女性医師抄録作成と索引作成職歴の移動テレビ会議テレワーキングヒト女 (Link to Publication Site) ● Publication site (DOI): 10.5833/jjgs.2022.sr005 (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1390857226420483072 ● Search Scopus @ Elsevier (DOI): 10.5833/jjgs.2022.sr005 (DOI: 10.5833/jjgs.2022.sr005, CiNii: 1390857226420483072)
13.	Yuuma Wada, Masaaki Nishi, Kouzou Yoshikawa, Chie Takasu, Takuya Tokunaga, Toshihiro Nakao, Hideya Kashihara, Toshiaki Yoshimoto and Mitsuo Shimada : Lymph node response to neoadjuvant chemotherapy as an independent prognostic factor in gastric cancer., Oncology Letters, Vol.24, No.5, 415, 2022. (Summary) Previous studies have revealed the usefulness of neoadjuvant chemotherapy (NAC) followed by surgery for clinical stage III gastric cancer (GC). The tumor volume at the primary tumor site (PT) is sometimes difficult to measure because of the luminal structure; therefore, evaluation of the lymph node (LN) response to NAC may help to more accurately predict survival outcomes. The present study therefore evaluated the LN response to NAC for prediction of survival outcomes in patients with GC. The study involved 160 patients with clinical stage III GC who underwent NAC (n=14) and upfront surgery (n=146). PT and LN responses to NAC were evaluated, various clinicopathological factors were evaluated and Cox proportional hazard regression analyses were performed to determine survival outcomes. Overall survival (OS) and disease-free survival (DFS) were not significantly different between patients who underwent NAC and those who underwent upfront surgery (OS, P=0.71; DFS, P=0.50). However, although there were no significant differences in PT responses, patients classified as LN non-responders to NAC had a significantly worse prognosis compared with patients classified as LN responders in terms of DFS (PT, P=0.93; LN, P<0.01) and OS (PT, P=0.84; LN, P<0.01). Moreover, a higher neutrophil-lymphocyte ratio tended to be associated with poor DFS [univariate: hazard ratio (HR)=4.23, P=0.06; multivariate: HR=6.45, P=0.04]. Finally, an LN response to NAC was significantly better for prediction of recurrence (univariate, HR=7.79, 95% confidence interval=1.16-63.51, P=0.02; multivariate, HR=7.44, P=0.01). Overall, the current study revealed the clinical importance of the LN response to NAC for predicting survival outcomes in patients with GC. These findings highlight the potential clinical impact of optimizing treatment strategies to improve the selection and management of patients. (Link to Publication Site) ● Publication site (DOI): 10.3892/ol.2022.13535 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 36245824 ● Search Scopus @ Elsevier (PMID): 36245824 ● Search Scopus @ Elsevier (DOI): 10.3892/ol.2022.13535 (DOI: 10.3892/ol.2022.13535, PubMed: 36245824)
14.	Toshihiro Nakao, Mitsuo Shimada, Kouzou Yoshikawa, Takuya Tokunaga, Masaaki Nishi, Hideya Kashihara, Chie Takasu, Yuuma Wada and Toshiaki Yoshimoto : Computed tomography texture analysis for the prediction of lateral pelvic lymph node metastasis of rectal cancer., World Journal of Surgical Oncology, Vol.20, No.1, 281, 2022. (Summary) This study aimed to investigate the usefulness of computed tomography (CT) texture analysis in the diagnosis of lateral pelvic lymph node (LPLN) metastasis of rectal cancer. This was a retrospective cohort study of 45 patients with rectal cancer who underwent surgery with LPLN dissection at Tokushima University Hospital from January 2017 to December 2021. The texture analysis of the LPLNs was performed on preoperative CT images, and 18 parameters were calculated. The correlation between each parameter and pathological LPLN metastasis was evaluated. The texture parameters were compared between pathologically metastasis-positive LPLNs and metastasis-negative LPLNs. A total of 40 LPLNs were extracted from 25 patients by preoperative CT scans. No LPLNs could be identified in the remaining 19 patients. Eight of the 25 patients had pathologically positive LPLN metastasis. Extracted LPLNs were analyzed by the texture analysis. Pathologically metastasis-positive LPLNs had significantly lower mean Hounsfield unit, gray-level co-occurrence matrix (GLCM) energy, and GLCM Entropy_log2 values, and a significantly larger volume than pathologically metastasis-negative LPLNs. Multivariate analysis revealed that the independent predictive factors for LPLN metastasis were volume (a conventional parameter) (odds ratio 7.81, 95% confidence interval 1.42-43.1, p value 0.018) and GLCM Entropy_log2 (a texture parameter) (odds ratio 12.7, 95% confidence interval 1.28-126.0, p value 0.030). The combination of both parameters improved the diagnostic specificity while maintaining the sensitivity compared with each parameter alone. Combining the CT texture analysis with conventional diagnostic imaging may increase the accuracy of the diagnosis of LPLN metastasis of rectal cancer. (Keyword) Humans / Lymph Node Excision / Lymph Nodes / Lymphatic Metastasis / Rectal Neoplasms / Retrospective Studies / Tomography, X-Ray Computed (Tokushima University Institutional Repository) ● Metadata: 2010865 (Link to Publication Site) ● Publication site (DOI): 10.1186/s12957-022-02750-8 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 36057660 ● Search Scopus @ Elsevier (PMID): 36057660 ● Search Scopus @ Elsevier (DOI): 10.1186/s12957-022-02750-8 (Tokushima University Institutional Repository: 2010865, DOI: 10.1186/s12957-022-02750-8, PubMed: 36057660)
15.	Toshihiro Nakao, Mitsuo Shimada, Kouzou Yoshikawa, Takuya Tokunaga, Masaaki Nishi, Hideya Kashihara, Chie Takasu, Yuuma Wada, Toshiaki Yoshimoto and Syoko Yamashita : Impact of osteopenia and neutropenia in patients with colorectal cancer treated with FOLFOXIRI: a retrospective cohort study., International Journal of Clinical Oncology, Vol.27, No.9, 1439-1449, 2022. (Summary) This study was performed to assess the impact of osteopenia on chemotherapy-induced neutropenia and the prognosis for patients treated with FOLFOXIRI for colorectal cancer. In total, 77 patients who underwent FOLFOXIRI for un-resectable metastatic and advanced colorectal cancer were retrospectively evaluated. Osteopenia was evaluated by the bone mineral density, which was measured using the average pixel density of the trabecular bone in the 11th thoracic vertebra by computed tomography before the introduction of chemotherapy. The relationship between osteopenia and neutropenia was evaluated. Progression-free survival and overall survival of patients with osteopenia and patients with neutropenia were evaluated. Grade ≥ 3 neutropenia was significantly more common in patients with than without osteopenia (p = 0.002). The multivariate analysis showed that osteopenia was a significant independent predictive factor for grade ≥ 3 neutropenia (p = 0.016). There was no significant difference in progression-free survival or overall survival between patients with and without osteopenia. Patients with grade ≥ 3 neutropenia tended to have a higher progression-free survival rate than others (p = 0.059). The overall survival rate was significantly higher in patients with grade ≥ 3 neutropenia than in others (p = 0.011). Osteopenia might be a predictor of chemotherapy-induced neutropenia, and neutropenia might be a prognostic factor for progression-free survival and overall survival in patients with colorectal cancer treated with FOLFOXIRI. (Keyword) Antineoplastic Agents / Antineoplastic Combined Chemotherapy Protocols / Bevacizumab / Bone Diseases, Metabolic / Camptothecin / Colorectal Neoplasms / Fluorouracil / Humans / Leucovorin / Neutropenia / Organoplatinum Compounds / Retrospective Studies (Link to Publication Site) ● Publication site (DOI): 10.1007/s10147-022-02199-5 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 35908137 ● Search Scopus @ Elsevier (PMID): 35908137 ● Search Scopus @ Elsevier (DOI): 10.1007/s10147-022-02199-5 (DOI: 10.1007/s10147-022-02199-5, PubMed: 35908137)
16.	Takuya Tokunaga, Maki Sugimoto, Yu Saitou, Hideya Kashihara, Kouzou Yoshikawa, Toshihiro Nakao, Masaaki Nishi, Chie Takasu, Yuuma Wada, Toshiaki Yoshimoto, Shoko Yamashita, Yosuke Iwakawa, Noriko Yokota and Mitsuo Shimada : Intraoperative holographic image-guided surgery in a transanal approach for rectal cancer., Langenbeck's Archives of Surgery / Deutsche Gesellschaft für Chirurgie, Vol.407, No.6, 2579-2584, 2022. (Summary) Urethral injury is one of the most important complications in transanal total mesorectal excision (TaTME) in male patients with rectal cancer. The purpose of this study was to investigate holographic image-guided surgery in TaTME. Polygon (stereolithography) files were created and exported from SYNAPSE VINCENT, and then uploaded into the Holoeyes MD system (Holoeyes Inc., Tokyo, Japan). After uploading the data, the three-dimensional image was automatically converted into a case-specific hologram. The hologram was then installed into the head mount display, HoloLens (Microsoft Corporation, Redmond, WA). The surgeons and assistants wore the HoloLens when they performed TaTME. In a Wi-Fi-enabled operating room, each surgeon, wearing a HoloLens, shared the same hologram and succeeded in adjusting the hologram by making simple hand gestures from their respective angles. The hologram contributed to better comprehension of the positional relationships between the urethra and the surrounding pelvic organs during surgery. All surgeons were able to properly determine the dissection line. This first experience suggests that intraoperative holograms contributed to reducing the risk of urethral injury and understanding transanal anatomy. Intraoperative holograms have the potential to become a new next-generation surgical support tool for use in spatial awareness and the sharing of information between surgeons. (Keyword) Dissection / Humans / Laparoscopy / Male / Postoperative Complications / Proctectomy / Rectal Neoplasms / Rectum / Surgery, Computer-Assisted / Transanal Endoscopic Surgery (Link to Publication Site) ● Publication site (DOI): 10.1007/s00423-022-02607-4 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 35840706 ● Search Scopus @ Elsevier (PMID): 35840706 ● Search Scopus @ Elsevier (DOI): 10.1007/s00423-022-02607-4 (DOI: 10.1007/s00423-022-02607-4, PubMed: 35840706)
17.	Yuuma Wada, Masaaki Nishi, Kozo Yoshikawa, Chie Takasu, Takuya Tokunaga, Toshihiro Nakao, Hideya Kashihara, Toshiaki Yoshimoto and Mitsuo Shimada : Preoperative nutrition and exercise intervention in frailty patients with gastric cancer undergoing gastrectomy., International Journal of Clinical Oncology, Vol.27, No.9, 1421-1427, 2022. (Summary) The frailty was associated with the worse surgical outcomes and poor prognosis in several cancers. Therefore, we aimed to identify the usefulness of nutrition and exercise intervention (NEI) in frailty patients with GC. We analyzed 58 frailty patients with GC who underwent radical surgery. Among these, 15 patients were performed NEI by nutritional and rehabilitation support team. We compared the surgical outcomes between NEI and non-NEI groups with frailty patients and evaluated the nutrition and rehabilitation markers in pre- and post-NEI groups. The postoperative complication of NEI groups was 6.7% and less than that of non-NEI groups (p = 0.08). The mean postoperative hospital stay of NEI groups was 13.0 ± 1.0 days for NEI groups and significantly shorter than that of non-NEI groups (p = 0.03). The NLR was 4.3 ± 0.6 for pre-NEI and significantly improved by NEI between pre- and post-NEI (p = 0.03). We identified the clinical importance of NEI for improving the surgical outcomes in frailty patients with GC. Our findings highlight the potential clinical impact of optimizing treatment strategies to select and manage the frailty patients. (Keyword) Exercise Therapy / Frailty / Gastrectomy / Humans / Postoperative Complications / Preoperative Care / Stomach Neoplasms (Link to Publication Site) ● Publication site (DOI): 10.1007/s10147-022-02202-z (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 35771395 ● Search Scopus @ Elsevier (PMID): 35771395 ● Search Scopus @ Elsevier (DOI): 10.1007/s10147-022-02202-z (DOI: 10.1007/s10147-022-02202-z, PubMed: 35771395)
18.	Masaaki Nishi, Yuuma Wada, Kouzou Yoshikawa, Chie Takasu, Takuya Tokunaga, Toshihiro Nakao, Hideya Kashihara, Toshiaki Yoshimoto, Chiharu Nakasu and Mitsuo Shimada : Pincer Approach to Gastrosplenic Ligament in Robotic Total Gastrectomy for Gastric Cancer., Journal of Gastrointestinal Surgery, Vol.26, No.7, 1552-1555, 2022. (Keyword) Gastrectomy / Humans / Laparoscopy / Ligaments / Retrospective Studies / Robotic Surgical Procedures / Robotics / Stomach Neoplasms / Treatment Outcome (Link to Publication Site) ● Publication site (DOI): 10.1007/s11605-022-05356-3 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 35578006 ● Search Scopus @ Elsevier (PMID): 35578006 ● Search Scopus @ Elsevier (DOI): 10.1007/s11605-022-05356-3 (DOI: 10.1007/s11605-022-05356-3, PubMed: 35578006)
19.	Toshihiro Nakao, Mitsuo Shimada, Kouzou Yoshikawa, Takuya Tokunaga, Masaaki Nishi, Hideya Kashihara, Chie Takasu, Yuuma Wada, Toshiaki Yoshimoto, Syoko Yamashita and Yosuke Iwakawa : Vascular variations encountered during laparoscopic surgery for transverse colon, splenic flexure, and descending colon cancer: a retrospective cohort study., BMC Surgery, Vol.22, No.1, 170, 2022. (Summary) Laparoscopic surgery for cancer located in the transverse colon or splenic flexure is difficult because of vascular variability in this region and adjacent vital organs such as the pancreas, spleen, and duodenum. This retrospective cohort study involved 51 patients who underwent laparoscopic surgery for colon cancer at Tokushima University Hospital from July 2015 to December 2020. Variations of the middle colic artery (MCA), left colic artery (LCA), middle colic vein (MCV), and first jejunal vein (FJV) and short-term outcomes of laparoscopic surgery in patients with each vascular variation were evaluated. Variations of the MCA, LCA, MCV, and FJV were classified into four, three, five, and three patterns, respectively. The short-term outcomes of laparoscopic surgery for transverse colon cancer in patients with MCA variations and those with FJV variations were evaluated, and no significant difference was found in the operation time, blood loss, postoperative complication rate, time from surgery to start of dietary intake, or time from surgery to discharge among the different variations. Additionally, no significant differences were found in the short-term outcomes of laparoscopic surgery for descending colon cancer in patients with LCA variations. Preoperative assessment of vascular variations may contribute to the stability of short-term outcomes of laparoscopic surgery for transverse colon, splenic flexure, and descending colon cancer. (Keyword) Colectomy / Colon, Descending / Colon, Transverse / Colonic Neoplasms / Humans / Laparoscopy / Retrospective Studies (Tokushima University Institutional Repository) ● Metadata: 2010795 (Link to Publication Site) ● Publication site (DOI): 10.1186/s12893-022-01603-1 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 35538458 ● Search Scopus @ Elsevier (PMID): 35538458 ● Search Scopus @ Elsevier (DOI): 10.1186/s12893-022-01603-1 (Tokushima University Institutional Repository: 2010795, DOI: 10.1186/s12893-022-01603-1, PubMed: 35538458)
20.	Toshiaki Yoshimoto, Mitsuo Shimada, Takuya Tokunaga, Toshihiro Nakao, Masaaki Nishi, Chie Takasu, Hideya Kashihara, Yuuma Wada, Shohei Okikawa and Kouzou Yoshikawa : Blue light irradiation inhibits the growth of colon cancer and activation of cancer-associated fibroblasts., Oncology Reports, Vol.47, No.5, 2022. (Summary) Irradiation with a specific wavelength of light using light-emitting diodes (LEDs) has various effects on cells and organisms. Recently, the antitumor effects of visible blue light on tumor cells were reported; however, the mechanism and effects on the tumor microenvironment remain unclear. Human colon cancer cells (HCT-116) were injected into the rectal wall of nude mice. Tumors were irradiated with a 465-nm LED light at 30 mW/cm for 30 min. Tumor volumes and the expression levels of opsin 3 (Opn3), autophagy-related factors, cancer-associated fibroblast (CAF) markers, and programmed cell death 1-ligand (PD-L1) were measured. Additionally, human intestinal fibroblasts were cultured in HCT116-conditioned medium (CM) to prepare CAFs. CAFs were divided into an LED group and a control group, and the effect of the LED light on CAF activation in colon cancer cells was examined. Irradiation with blue LED light suppressed tumor growth; Opn3 expression was localized to the cell membrane in the LED group. Irradiated tumors exhibited increased autophagy-related gene expression. Furthermore, in the LED group, TGF-β and α-SMA expression levels in the fibroblasts were decreased. Regarding CAFs, α-SMA and IL-6 expression levels were decreased in the LED group. HCT-116 cells cultured in CAF-CM with LED irradiation showed no enhanced migration or invasion. In the HCT-116 cells cultured in CM of CAFs irradiated with LED, the relative increase in PD-L1 expression was lower than that noted in the CAF-CM without LED irradiation. Blue LED light may have a direct antitumor effect on colon cancer and also an inhibitory effect on CAFs. (Keyword) Animals / B7-H1 Antigen / Cancer-Associated Fibroblasts / Cell Movement / Cell Proliferation / Colonic Neoplasms / HCT116 Cells / Humans / Light / Mice / Mice, Nude / Rod Opsins / Tumor Microenvironment (Tokushima University Institutional Repository) ● Metadata: 2010860 (Link to Publication Site) ● Publication site (DOI): 10.3892/or.2022.8315 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 35417035 ● Search Scopus @ Elsevier (PMID): 35417035 ● Search Scopus @ Elsevier (DOI): 10.3892/or.2022.8315 (Tokushima University Institutional Repository: 2010860, DOI: 10.3892/or.2022.8315, PubMed: 35417035)
21.	Toshihiro Nakao, Mitsuo Shimada, Kouzou Yoshikawa, Takuya Tokunaga, Masaaki Nishi, Hideya Kashihara, Chie Takasu, Yuuma Wada, Toshiaki Yoshimoto, Syoko Yamashita and Yosuke Iwakawa : Risk factors for postoperative ileus after diverting loop ileostomy closure., BMC Surgery, Vol.22, No.1, 131, 2022. (Summary) Postoperative ileus is one of the most common complications after diverting loop ileostomy closure. Some reports have investigated the risk factors for postoperative complications or ileus after ileostomy closure; however, these studies did not evaluate the index surgery sufficiently. In this study, we evaluated the risk factors, including the details of the index surgery, for ileus after diverting ileostomy closure. This was a retrospective study of patients who underwent ileostomy closure following index surgery for rectal cancer. Patients who developed postoperative ileus [POI (+)] and patients who did not [POI (-)] after ileostomy closure were compared. Sixty-eight patients were evaluated and were divided into two groups: POI (+) (n = 11) and POI (-) (n = 57), and the groups were compared. There were no significant differences in the details of the index surgery, operative procedure, transanal total mesorectal excision, lateral lymph node dissection, operating time, or blood loss. The incidence of Clavien-Dindo grade ≥ III complications and adjuvant chemotherapy after index surgery were significantly higher in the POI (+) group. The incidence of Clavien-Dindo grade ≥ III complications and adjuvant chemotherapy after index surgery may increase the risk of postoperative ileus after ileostomy closure. (Keyword) Humans / Ileostomy / Ileus / Postoperative Complications / Rectal Neoplasms / Retrospective Studies / Risk Factors (Tokushima University Institutional Repository) ● Metadata: 2010794 (Link to Publication Site) ● Publication site (DOI): 10.1186/s12893-022-01583-2 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 35392877 ● Search Scopus @ Elsevier (PMID): 35392877 ● Search Scopus @ Elsevier (DOI): 10.1186/s12893-022-01583-2 (Tokushima University Institutional Repository: 2010794, DOI: 10.1186/s12893-022-01583-2, PubMed: 35392877)
22.	Masaaki Nishi, Mitsuo Shimada, Yuji Morine, Kouzou Yoshikawa, Takuya Tokunaga, Toshihiro Nakao, Hideya Kashihara, Chie Takasu, Toshiaki Yoshimoto and Yuuma Wada : 【外科代謝栄養と東洋医学:漢方による周術期管理へのサポート】大建中湯による周術期管理のサポート, The Japanese Journal of Surgical Metabolism and Nutrition, Vol.56, No.2, 59-61, 2022. (Summary) 近年では漢方の分子生物学的な作用機序の解明が進み，臨床においても質の高いランダム化比較試験により漢方の有用性が明らかになってきた．現在では大建中湯を含む多くの漢方製剤が広く臨床の現場で用いられている．大建中湯は乾姜，人参，山椒の3つの生薬に膠飴を加えた漢方で，外科領域においては癒着性イレウスや麻痺性イレウス，過敏性腸症候群，クローン病などを適応とし，消化管運動促進作用，腸管血流増加作用，抗炎症作用などが報告されている．近年では，食道・胃・大腸・肝臓・膵臓・肝移植外科それぞれの領域でランダム化試験が実施され，大建中湯の周術期管理における有効性が証明されている．また分子生物学的なメカニズムについても解明がすすみ，現在，大建中湯は消化管外科・肝胆膵外科の分野を問わず消化器外科全般における周術期管理のkey drugとして位置付けられている．本稿では消化器外科領域における大建中湯による周術期管理のサポートについて概説する．(著者抄録) (Keyword) 消化管運動消化器外科バクテリアルトランスロケーション周術期管理 *大建中湯(薬理学,治療的利用) 伊東細胞腫瘍微小環境ヒト (Link to Publication Site) ● Publication site (DOI): 10.11638/jssmn.56.2_59 (Link to Search Site for Scientific Articles) ● Search Scopus @ Elsevier (DOI): 10.11638/jssmn.56.2_59 (DOI: 10.11638/jssmn.56.2_59)
23.	Toshihiro Nakao, Mitsuo Shimada, Kouzou Yoshikawa, Takuya Tokunaga, Masaaki Nishi, Hideya Kashihara, Chie Takasu, Yuuma Wada, Toshiaki Yoshimoto, Shoko Yamashita and Yosuke Iwakawa : The correlation of immunoscore and frailty in colorectal cancer., International Journal of Clinical Oncology, Vol.27, No.3, 528-537, 2022. (Summary) The Immunoscore is a useful prognostic and predictive factor for colorectal cancer. Frailty predicts overall and recurrence-free survival following resection of colorectal cancer, and the immunosuppressive state of frailty might affect tumor progression. This study investigated the relationship between the Immunoscore and frailty in colorectal cancer. This retrospective study included patients who underwent radical surgery for stage II and III colorectal cancer (n = 108). Patients were divided into frail (n = 11) and non-frail (n = 97) groups, and low (IS0-2) (n = 70) and high (IS3-4) Immunoscore groups (n = 38), for comparison. American Society of Anesthesiologists physical status was higher, tumor diameter was larger, number of well-differentiated tumors was higher, albumin was lower, 5-year overall survival (OS) was lower (frail group: 50.0%, non-frail group: 90.5%, p < 0.001) and 5-year disease-free survival (DFS) was lower (frail group: 36.4%, non-frail group: 75.2%, p = 0.024) in the frail than in the non-frail group. Left colon cancer was more, 5-year OS was lower (IS0-2 group: 82.0%, IS3-4 group: 96.7%, p = 0.040) and 5-year DFS was lower (IS0-2 group: 66.3%, IS3-4 group: 83.3%, p = 0.043) in the IS0-2 than in the IS3-4 group. The Immunoscore was lower in the frail than in the non-frail group. Immunoscore and frailty are prognostic and predictive factors in colorectal cancer, and they are correlated with each other. The immunosuppressive state from frailty might affect this correlation. (Keyword) Colonic Neoplasms / Colorectal Neoplasms / Disease-Free Survival / Frailty / Humans / Prognosis / Retrospective Studies (Link to Publication Site) ● Publication site (DOI): 10.1007/s10147-021-02096-3 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 34846645 ● Search Scopus @ Elsevier (PMID): 34846645 ● Search Scopus @ Elsevier (DOI): 10.1007/s10147-021-02096-3 (DOI: 10.1007/s10147-021-02096-3, PubMed: 34846645)
24.	Shohei Eto, Kouzou Yoshikawa, Toshiaki Yoshimoto, Chie Takasu, Hideya Kashihara, Masaaki Nishi, Takuya Tokunaga, Toshihiro Nakao, Jun Higashijima, Takashi Iwata and Mitsuo Shimada : Strategy for laparoscopic repair of inguinal hernia after robot-assisted radical prostatectomy., Asian Journal of Endoscopic Surgery, Vol.15, No.1, 155-161, 2022. (Summary) Robot-assisted radical prostatectomy (RARP) is nowadays being performed worldwide, and inguinal hernia (IH) continues to be a common complication of radical prostatectomy. Laparoscopic repair of IH is often difficult via internal dissection because of adhesion of the preperitoneal cavity. This study aimed to categorize the intraoperative condition of, and devise a strategy for, IH after RARP. Of 577 patients who underwent RARP, 18 developed IH. These 18 patients then underwent laparoscopic IH repair using the transabdominal preperitoneal approach (TAPP) or modified intraperitoneal onlay mesh repair (mIPOM). Internal dissection was categorized into two groups according to the appearance of Cooper's ligament (exposed or not exposed). After RARP, four patients had exposure of Cooper's ligament while 14 patients showed no exposure. Both patients in the exposed group underwent TAPP and all patients in the not-exposed group underwent mIPOM. There was no significant difference between normal TAPP and RARP regarding operative factors, and IH recurrence was not observed. Laparoscopic repair of IH after RARP is rendered safe and efficient by using our categorization based on the exposure of Cooper's ligament and extension of preperitoneal space. (Keyword) Hernia, Inguinal / Herniorrhaphy / Humans / Laparoscopy / Male / Prostatectomy / Robotics (Link to Publication Site) ● Publication site (DOI): 10.1111/ases.12985 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 34514724 ● Search Scopus @ Elsevier (PMID): 34514724 ● Search Scopus @ Elsevier (DOI): 10.1111/ases.12985 (DOI: 10.1111/ases.12985, PubMed: 34514724)
25.	Masaaki Nishi, Mitsuo Shimada, Kouzou Yoshikawa, Chie Takasu, Yuuma Wada, Takuya Tokunaga, Toshihiro Nakao, Hideya Kashihara, Toshiaki Yoshimoto and Shoko Yamashita : Propensity Score-Matched Analysis of the Short- and Long-Term Outcomes of Robotic Versus Laparoscopic Gastrectomy for Gastric Cancer., Annals of Surgical Oncology, Vol.29, No.6, 3887-3895, 2022. (Summary) Robotic gastrectomy (RG) has been rapidly adopted for gastric cancer (GC) treatment. However, the benefits of RG over laparoscopic gastrectomy (LG) for GC remain unclear. A total of 451 patients who underwent either RG (n = 83) or LG (n = 368) for GC were enrolled in this study. A 1:1 matched, propensity score-matched analysis was performed using the following factors: age, sex, body mass index, pT, pN, pStage, tumor location, vessel invasion, tumor markers, surgical procedure, reconstruction method, extent of lymphadenectomy, and Endoscopic Surgical Skill Qualification System qualified surgeon as an operator. The surgical outcomes of the two groups were compared. A well-balanced cohort of 158 patients was analyzed (n = 79 in the RG group, n = 79 in the LG group). Regarding the short-term outcomes, the respective blood loss volume, drain amylase content, and number of retrieved lymph nodes in the RG and LG groups were 38.62 ± 73.06 ml and 67.53 ± 108.20 ml (p < 0.05), 450 ± 371 IU/l and 1590 ± 6392 IU/l (p < 0.01), and 35.02 ± 15.51 and 25.28 ± 11.70 (p < 0.01). The morbidity rate was similar between the RG and LG groups (not significant [NS]). Regarding the long-term survival outcomes, there were no intergroup differences in 3-year overall survival (91.72% in the RG group vs. 83.39% in the LG group: NS) and 3-year, disease-free survival (93.31% in the vs. 90.44%: NS). RG was safe and contributed to better short-term outcomes and similar long-term survival outcomes compared with LG. (Keyword) Gastrectomy / Humans / Laparoscopy / Postoperative Complications / Propensity Score / Retrospective Studies / Robotic Surgical Procedures / Stomach Neoplasms / Treatment Outcome (Link to Publication Site) ● Publication site (DOI): 10.1245/s10434-021-11203-7 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 35006502 ● Search Scopus @ Elsevier (PMID): 35006502 ● Search Scopus @ Elsevier (DOI): 10.1245/s10434-021-11203-7 (DOI: 10.1245/s10434-021-11203-7, PubMed: 35006502)
26.	Kouzou Yoshikawa, Mitsuo Shimada, Takuya Tokunaga, Toshihiro Nakao, Masaaki Nishi, Chie Takasu, Hideya Kashihara, Yuuma Wada, Toshiaki Yoshimoto and Shoko Yamashita : Short-term outcomes of laparoscopic / robotic gastrectomy compared with open gastrectomy for advanced gastric cancer following chemotherapy., The Journal of Medical Investigation : JMI, Vol.69, No.3.4, 261-265, 2022. (Summary) Purpose : This study aimed to investigate the short-term outcomes of laparoscopic gastrectomy / robotic gastrectomy after chemotherapy in patients with advanced gastric cancer and compare these outcomes with those of open gastrectomy. Methods : Fifty patients who underwent radical gastrectomy for advanced gastric cancer after chemotherapy between 2007 and 2021 were retrospectively analyzed. The patients were divided into two groups : the laparoscopic gastrectomy / robotic gastrectomy (n = 11) and open gastrectomy (n = 39) groups. The short-term outcomes of these procedures were subsequently examined. Results : The laparoscopic gastrectomy / robotic gastrectomy group had significantly shorter hospital stays and lower intraoperative blood loss than the open gastrectomy group. The overall complication rates were 12.8% (5 of 39 patients) and 0% (0 of 11 patients) in the open gastrectomy and laparoscopic gastrectomy / robotic gastrectomy groups, respectively (P = 0.1). Conclusions : Laparoscopic gastrectomy / robotic gastrectomy may be a surgical option after chemotherapy for patients with advanced gastric cancer. J. Med. Invest. 69 : 261-265, August, 2022. (Keyword) Gastrectomy / Humans / Laparoscopy / Retrospective Studies / Robotic Surgical Procedures / Stomach Neoplasms / Treatment Outcome (Tokushima University Institutional Repository) ● Metadata: 2010525 (Link to Publication Site) ● Publication site (DOI): 10.2152/jmi.69.261 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 36244778 ● Search Scopus @ Elsevier (PMID): 36244778 ● Search Scopus @ Elsevier (DOI): 10.2152/jmi.69.261 (Tokushima University Institutional Repository: 2010525, DOI: 10.2152/jmi.69.261, PubMed: 36244778)
27.	Shohei Eto, Kouzou Yoshikawa, Yukako Takehara, Toshiaki Yoshimoto, Chie Takasu, Hideya Kashihara, Masaaki Nishi, Takuya Tokunaga, Toshihiro Nakao, Jun Higashijima, Takashi Iwata and Mitsuo Shimada : Usefulness of a multidisciplinary surgical site infection team in colorectal surgery., The Journal of Medical Investigation : JMI, Vol.68, No.3.4, 256-259, 2021. (Summary) Background : Surgical site infection (SSI) is an adverse event that places a major burden on patients and staff. In this study, we examined the occurrence of SSI and the characteristics of patients referred to the SSI team after colorectal surgery. Methods : In total, 955 patients underwent colorectal surgery at our hospital from 2014 to 2019. Of these 955 patients, 516 received therapeutic support by the SSI team from 2017 to 2019. All patients were evaluated using an SSI surveillance sheet, and we checked for reports of SSI once a month. Each attending physician performed SSI prophylaxis (use of new instruments before wound irrigation and closure). Results : SSI occurred in 80 (8.4%) patients. The incidence of SSI and the incidence of surface SSI were higher in the patients who did not receive intervention by the SSI team than in the patients who did. Organ /pace SSI occurred in 18 patients. Among patients with surface SSI, Enterococcus was the most commonly detected bacteria. Among the 18 patients with organ /pace SSI, 5 developed anastomotic leakage and 4 developed intra-abdominal abscesses. Conclusions : An SSI team for prevention and treatment of infection may contribute to reduction of SSI. J. Med. Invest. 68 : 256-259, August, 2021. (Keyword) Colorectal Surgery / Humans / Incidence / Risk Factors / Surgical Wound Infection / Therapeutic Irrigation (Tokushima University Institutional Repository) ● Metadata: 2009393 (Link to Publication Site) ● Publication site (DOI): 10.2152/jmi.68.256 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 34759140 ● Search Scopus @ Elsevier (PMID): 34759140 ● Search Scopus @ Elsevier (DOI): 10.2152/jmi.68.256 (Tokushima University Institutional Repository: 2009393, DOI: 10.2152/jmi.68.256, PubMed: 34759140)
28.	Shohei Eto, Kouzou Yoshikawa, Masaaki Nishi, Jun Higashijima, Takuya Tokunaga, Toshihiro Nakao, Hideya Kashihara, Chie Takasu, Takashi Iwata and Mitsuo Shimada : Programmed cell death protein 1 expression is an independent prognostic factor in gastric cancer after curative resection., Gastric Cancer, Vol.19, No.2, 466-471, 2016. (Summary) Programmed cell death protein 1 (PD-1) and its ligand PD-L1 downregulate T cell activation and are related to immune tolerance. The aim of this study was to clarify the significance of PD-1 and PD-L1 expression and to analyze the relationships among PD-1, PD-L1, and Foxp3 expression in gastric cancer. A total of 105 patients who underwent curative gastrectomy for stage II/III gastric cancer were included in this study. PD-1, PD-L1, and Foxp3 expression were examined by immunohistochemistry and related to prognostic factors by univariate and multivariate analyses. PD-1 expression was correlated with both PD-L1 and Foxp3 expression. Disease-free survival (DFS) was significantly poorer in PD-1-positive patients than in PD-1-negative patients (3-year DFS, 36.1 % vs. 64.7 %, respectively; p < 0.05). Overall survival also tended to be poorer in PD-L1-positive patients than in PD-L1-negative patients. Univariate analysis identified sex, T factor, lymphatic invasion, and PD-1 positivity as significant predictors of poor DFS. Multivariate analysis confirmed male sex, lymphatic invasion, and positive PD-1 expression as independent prognostic indicators. PD-1 expression is associated with a poor prognosis and is correlated with PD-L1 and Foxp3 expression in patients with gastric cancer. (Keyword) Adult / Aged / Aged, 80 and over / Antigens, CD274 / Biomarkers, Tumor / Female / Forkhead Transcription Factors / Gastrectomy / Humans / Kaplan-Meier Estimate / Male / Middle Aged / Prognosis / Programmed Cell Death 1 Receptor / Stomach Neoplasms (Tokushima University Institutional Repository) ● Metadata: 2002898 (Link to Publication Site) ● Publication site (DOI): 10.1007/s10120-015-0519-7 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 26210691 ● Summary page in Scopus @ Elsevier: 2-s2.0-84937959229 (Tokushima University Institutional Repository: 2002898, DOI: 10.1007/s10120-015-0519-7, PubMed: 26210691, Elsevier: Scopus)
29.	Kouzou Yoshikawa, Mitsuo Shimada, Jun Higashijima, Toshihiro Nakao, Masaaki Nishi, Hideya Kashihara and Chie Takasu : Limited lymph node dissection in elderly patients with gastric cancer., The Journal of Medical Investigation : JMI, Vol.63, No.1-2, 91-95, 2016. (Summary) The number of elderly patients with gastric cancer is continuing to increase along with the life expectancy of the general population. The purpose of this study was to investigate both the impact of age on postoperative outcome and the effect of limited lymph node dissection for elderly patients. Patients were classified into the following three groups: Group A, ·80 years old (n=44); Group B, 70-80 years old (n=139); Group C, <70 years old (n=219). Postoperative complication and survival rates were compared between the three groups Results: Limited lymph node dissection was performed significantly more frequently in Group A. In terms of surgery-related complications, no significant difference was seen between groups. In terms of general related complications, the complication rate increased with age, from 4% in Group C to 13% in Group B and 14% in Group A (p<0.05 each). Although limited lymph node dissection was frequently performed in Group A, cancer-specific survival showed no significant difference in R0 patients. Limited lymph node dissection for gastric cancer did not affect the cancer-specific survival in elderly patients. (Keyword) Adult / Age Factors / Aged / Aged, 80 and over / Female / Humans / Japan / Lymph Node Excision / Male / Middle Aged / Postoperative Complications / Stomach Neoplasms / Survival Analysis (Tokushima University Institutional Repository) ● Metadata: 2004348 (Link to Publication Site) ● Publication site (DOI): 10.2152/jmi.63.91 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 27040060 ● Search Scopus @ Elsevier (PMID): 27040060 ● Search Scopus @ Elsevier (DOI): 10.2152/jmi.63.91 (Tokushima University Institutional Repository: 2004348, DOI: 10.2152/jmi.63.91, PubMed: 27040060)

Review, Commentary:

1.	Kouzou Yoshikawa, Mitsuo Shimada, Nobuhiro Kurita, Takashi Iwata, Jun Higashijima, Toshihiro Nakao, Masaaki Nishi, Chie Takasu, 江藤祥平, 吉川雅登 and 寺奥大貴 : 【食道癌・胃癌におけるロボット支援手術の有用性】地方での胃癌に対するロボット支援手術導入の現状と問題点, Japanese Journal of Cancer Clinics, Vol.60, No.3, 319-323, Jul. 2014. (Keyword) 和文論文

Proceeding of International Conference:

1.	Yuuma Wada, Masaaki Nishi, Kouzou Yoshikawa, Chie Takasu, Takuya Tokunaga, Toshihiro Nakao, Hideya Kashihara, Toshiaki Yoshimoto and Mitsuo Shimada : Circulating exosomal microRNA signature to predict peritoneal metastasis in patients with advanced gastric cancer., ASCO-GI, San Francisco, Jan. 2024.
2.	Toshihiro Nakao, Mitsuo Shimada, Kouzou Yoshikawa, Takuya Tokunaga, Masaaki Nishi, Hideya Kashihara, Chie Takasu, Yuuma Wada and Toshiaki Yoshimoto : Immunoscore and Frailty in Colorectal Cancer, IASGO-CME Advanced Post-Graduate Course in Kobe 2023, Kobe, Nov. 2023.
3.	Hideya Kashihara, Mitsuo Shimada, Kouzou Yoshikawa, Jun Higashijima, Toshihiro Nakao, Masaaki Nishi and Chie Takasu : Risk factoes of the resurrence after laparoscopic gastrectomy for gastric cancer., Society American Gastrointestinal Endoscopic Surgeons (SAGES 2016), Boston, Mar. 2016.
4.	Toshihiro Nakao, Mitsuo Shimada, Kouzou Yoshikawa, Jun Higashijima, Takuya Tokunaga, Masaaki Nishi, Chie Takasu and Hideya Kashihara : Novel prognostic factor in the colorectal cancer patients who underwent laparoscopic surgery., Society American Gastrointestinal Endoscopic Surgeons (SAGES 2016), Boston, Mar. 2016.
5.	Jun Higashijima, Mitsuo Shimada, Takashi Iwata, Kouzou Yoshikawa, Toshihiro Nakao, Masaaki Nishi, Hideya Kashihara and Chie Takasu : Usefulness of blood flow Evaluation by indocyanine green fluorescent system in laparoscopic colectomy., Society American Gastrointestinal Endoscopic Surgeons (SAGES 2016), Boston, Mar. 2016.
6.	Takashi Iwata, Masashi Akaike, Kouzou Yoshikawa, Jun Higashijima, Toshihiro Nakao, Masaaki Nishi, Chie Takasu and Mitsuo Shimada : Trial of the filipped classroom for open suturing and simulated laparoscopic cholecystectomy for medical., Society American Gastrointestinal Endoscopic Surgeons (SAGES 2016), Boston, Mar. 2016.
7.	Masaaki Nishi, Mitsuo Shimada, Kouzou Yoshikawa, Jun Higashijima, Toshihiro Nakao, Hideya Kashihara and Chie Takasu : Sarcopenia with modified glasgow prognostic score is a predictor of long term survival in patients with gastric cancer., 2016 Gastrointestinal Cancers Symposium, San Francisco, Jan. 2016.
8.	Kouzou Yoshikawa, Mitsuo Shimada, Jun Higashijima, Toshihiro Nakao, Masaaki Nishi, Hideya Kashihara and Chie Takasu : Impact of blue 465nm LED on suppression of cancer growth., 2016 Gastrointestinal Cancers Symposium, San Francisco, Jan. 2016.
9.	Toshihiro Nakao : A propensity score matched study of laparoscopic and open surgery for colorectal cancer., ACS Chicago 2015, Oct. 2015.
10.	Toshihiro Nakao, Mitsuo Shimada, Kouzou Yoshikawa, Jun Higashijima, Masaaki Nishi, Hideya Kashihara and Chie Takasu : Efeect of preoperative chemoradiotherapy on the long-term outcome for lower rectal cancer, Mongolia Japanese joint Symposium UPPER GI CANCER MANAGEMWNT, Mongol, Sep. 2015.
11.	Jun Higashijima, Mitsuo Shimada, Takashi Iwata, Kouzou Yoshikawa, Toshihiro Nakao, Masaaki Nishi, Hideya Kashihara and Chie Takasu : Significance of blood flow evaluation by indocyanine green fluorescent system in laparoscopic anterior resection, Mongolia Japanese joint Symposium UPPER GI CANCER MANAGEMWNT, Mongol, Sep. 2015.
12.	Takata Atsushi, Mitsuo Shimada, Kouzou Yoshikawa, Jun Higashijima, Toshihiro Nakao, Masaaki Nishi and Hideya Kashihara : The effets of bariatric surgery on obesity and obesity-related disease from benchi to bedsaide, Mongolia Japanese joint Symposium UPPER GI CANCER MANAGEMWNT, Mongol, Sep. 2015.
13.	Takata Atsushi, Mitsuo Shimada, Kouzou Yoshikawa, Jun Higashijima, Toshihiro Nakao, Masaaki Nishi, Hideya Kashihara and Chie Takasu : Utility of virtual three-dimensional image analysis for laparoscopic gastrectomy conducted by trainee surgeons., 46th World Congress of Surgery (WCS)2015, Bangkok, Aug. 2015.
14.	Kouzou Yoshikawa, Mitsuo Shimada, Jun Higashijima, Takuya Tokunaga, Toshihiro Nakao, Masaaki Nishi, Hideya Kashihara and Chie Takasu : The usefulness of KI-67 index as predictive factor for the rectal cancer with preoperative chemo-radiotherapy., 46th World Congress of Surgery (WCS)2015, Bangkok, Aug. 2015.
15.	Jun Higashijima, Mitsuo Shimada, Takashi Iwata, Kouzou Yoshikawa, Toshihiro Nakao, Masaaki Nishi, Hideya Kashihara, Chie Takasu and 江藤祥平 : Significance of blood flow evaluation by indocyanine green fluorescent system in laparoscopic anterior resection, IASGO 2015 post graduate course, Tokyo, Jun. 2015.
16.	Takashi Iwata, Masashi Akaike, Kouzou Yoshikawa, Jun Higashijima, Toshihiro Nakao, Masaaki Nishi, Chie Takasu, 江藤祥平 and Mitsuo Shimada : Investigation of training for students who is weak in maneuver of laparoscopic surgery Laborer of the off-the-job training, Surgical Education Week, Seattle, Apr. 2015.
17.	Eto Shohei, Takashi Iwata, Kouzou Yoshikawa, Jun Higashijima, Takuya Tokunaga, Toshihiro Nakao, Masaaki Nishi, Chie Takasu and Mitsuo Shimada : Relationship of programmed death 1(PD-1)expression to the recurrence in gastric cancer., ASCO-GI 2015 Gastrointestinal Cancers Symposium, San Francisco, Jan. 2015.
18.	Jun Higashijima, Mitsuo Shimada, Takashi Iwata, Kouzou Yoshikawa, Toshihiro Nakao, Masaaki Nishi, Chie Takasu and Eto Shohei : Significance of platinum concentration in blood and red blood cell in patients with oxaliplatin-based chemotherapy., ASCO-GI 2015 Gastrointestinal Cancers Symposium, San Francisco, Jan. 2015.
19.	Masaaki Nishi, Mitsuo Shimada, Kouzou Yoshikawa, Jun Higashijima, Toshihiro Nakao, Chie Takasu, 寺奥大貴 and 江藤祥平 : Effect of light irradiation by light emitting diode on colon cancer cells and cancer stem cells., ASCO-GI 2015 Gastrointestinal Cancers Symposium, 271, San Francisco, Jan. 2015. (Keyword) 国際学会 (Link to Publication Site) ● Publication site (DOI): 10.1200/jco.2015.33.3_suppl.271 (Link to Search Site for Scientific Articles) ● Search Scopus @ Elsevier (DOI): 10.1200/jco.2015.33.3_suppl.271 (DOI: 10.1200/jco.2015.33.3_suppl.271)
20.	Toshihiro Nakao : Effect of preoperative chemoradiotherapy on the long-term outcome for lower rectal cancer., IASGO2014, オーストリア, Dec. 2014. (Keyword) 国際学会
21.	江藤祥平, Takashi Iwata, Kouzou Yoshikawa, Jun Higashijima, Takuya Tokunaga, Toshihiro Nakao, Masaaki Nishi, Chie Takasu and Mitsuo Shimada : Relationship of programmed death 1(PD-1)expression to the recurrence in gastric cancer., ASCO-GI 2015 Gastrointestinal Cancers Symposium, San Francisco, Jan. 2014. (Keyword) 国際学会
22.	Jun Higashijima, Mitsuo Shimada, Takashi Iwata, Kouzou Yoshikawa, Toshihiro Nakao, Masaaki Nishi, Chie Takasu and 江藤祥平 : Significance of platinum concentration in blood and red blood cell in patients with oxaliplatin-based chemotherapy., ASCO-GI 2015 Gastrointestinal Cancers Symposium, San Francisco, Jan. 2014. (Keyword) 国際学会

Proceeding of Domestic Conference:

1.	Yuuma Wada, Masaaki Nishi, Kouzou Yoshikawa, Chie Takasu, Takuya Tokunaga, Toshihiro Nakao, Hideya Kashihara, Toshiaki Yoshimoto and Mitsuo Shimada : 胃癌腹膜播種予測におけるエクソソームmiRNAの有用性, 第96回日本胃癌学会総会, Feb. 2024.
2.	Chie Takasu, Masaaki Nishi, Kouzou Yoshikawa, Takuya Tokunaga, Toshihiro Nakao, Hideya Kashihara, Yuuma Wada, Toshiaki Yoshimoto and Mitsuo Shimada : 局所進行胃癌に対するロボット支援手術の工夫と成績, 第96回日本胃癌学会総会, Feb. 2024.
3.	Masaaki Nishi, Mitsuo Shimada, Kouzou Yoshikawa, Chie Takasu, Yuuma Wada, Takuya Tokunaga, Toshihiro Nakao, Hideya Kashihara and Toshiaki Yoshimoto : 食道胃接合部腺癌に対する経裂孔ロボット支援手術, 第96回日本胃癌学会総会, Feb. 2024.
4.	Kouzou Yoshikawa, Mitsuo Shimada, Takuya Tokunaga, Toshihiro Nakao, Masaaki Nishi, Hideya Kashihara, Chie Takasu, Yuuma Wada and Toshiaki Yoshimoto : The ingenuity of robotic surgery for advanced gastric cancer, 第96回日本胃癌学会総会, Feb. 2024.
5.	Yuuma Wada, Masaaki Nishi, Kouzou Yoshikawa, Chie Takasu, Takuya Tokunaga, Toshihiro Nakao, Hideya Kashihara, Toshiaki Yoshimoto and Mitsuo Shimada : エクソソームmiRNAを用いての胃癌腹膜播種の予測, 第56回制癌剤適応研究会, Feb. 2024.
6.	Toshiaki Yoshimoto, Kouzou Yoshikawa, Takuya Tokunaga, Toshihiro Nakao, Masaaki Nishi, Hideya Kashihara, Chie Takasu, Yuuma Wada and Mitsuo Shimada : 下部直腸癌に対するTaTME併用ロボット支援下直腸切除術の有用性, 第120回日本消化器病学会四国支部例会, Dec. 2023.
7.	Toshiaki Yoshimoto, Kouzou Yoshikawa, Takuya Tokunaga, Toshihiro Nakao, Masaaki Nishi, Hideya Kashihara, Chie Takasu, Yuuma Wada and Mitsuo Shimada : ロボット支援前立腺全摘後の鼠径ヘルニアに対する腹腔鏡下ヘルニア修復術についての検討, 第36回日本内視鏡外科学会総会, Dec. 2023.
8.	Yuuma Wada, Masaaki Nishi, Kouzou Yoshikawa, Chie Takasu, Takuya Tokunaga, Toshihiro Nakao, Hideya Kashihara, Toshiaki Yoshimoto and Mitsuo Shimada : 腹腔鏡下胃癌手術におけるトレーニングプログラムの確立, 第36回日本内視鏡外科学会総会, Dec. 2023.
9.	Takuya Tokunaga, Mitsuo Shimada, Kouzou Yoshikawa, Toshihiro Nakao, Masaaki Nishi, Hideya Kashihara, Chie Takasu, Yuuma Wada and Toshiaki Yoshimoto : 直腸癌に対する経肛門的側方リンパ節郭清の手術手技と短期成績の検討, 第36回日本内視鏡外科学会総会, Dec. 2023.
10.	Chie Takasu, Masaaki Nishi, Kouzou Yoshikawa, Takuya Tokunaga, Toshihiro Nakao, Hideya Kashihara, Yuuma Wada, Toshiaki Yoshimoto and Mitsuo Shimada : 局所進行胃癌に対するロボット支援手術の工夫と成績, 第36回日本内視鏡外科学会総会, Dec. 2023.
11.	Hideya Kashihara, Mitsuo Shimada, Kouzou Yoshikawa, Takuya Tokunaga, Toshihiro Nakao, Masaaki Nishi, Chie Takasu, Yuuma Wada and Toshiaki Yoshimoto : 非アルコール性脂肪肝炎に対する減量・代謝改善手術の意義, 第36回日本内視鏡外科学会総会, Dec. 2023.
12.	Masaaki Nishi, Mitsuo Shimada, Kouzou Yoshikawa, Chie Takasu, Yuuma Wada, Takuya Tokunaga, Toshihiro Nakao, Hideya Kashihara and Toshiaki Yoshimoto : 食道胃接合部腺癌に対するロボット手術(経裂孔アプローチ)の有用性, 第36回日本内視鏡外科学会総会, Dec. 2023.
13.	Toshihiro Nakao, Mitsuo Shimada, Kouzou Yoshikawa, Takuya Tokunaga, Masaaki Nishi, Hideya Kashihara, Chie Takasu, Yuuma Wada and Toshiaki Yoshimoto : 他臓器浸潤を伴う直腸癌に対する経肛門アプローチの有用性, 第36回日本内視鏡外科学会総会, Dec. 2023.
14.	Kouzou Yoshikawa, Mitsuo Shimada, Takuya Tokunaga, Toshihiro Nakao, Masaaki Nishi, Hideya Kashihara, Chie Takasu, Yuuma Wada and Toshiaki Yoshimoto : 胃全摘OrVil法におけるピットフォールとトラブルシューティング, 第36回日本内視鏡外科学会総会, Dec. 2023.
15.	Toshiaki Yoshimoto, Takuya Tokunaga, 杉本真樹, Kouzou Yoshikawa, Toshihiro Nakao, Masaaki Nishi, Hideya Kashihara, Chie Takasu, Yuuma Wada and Mitsuo Shimada : 再発直腸癌に対する経肛門アプローチにおけるホログラムの有用性, 第32回日本コンピュータ外科学会大会, Dec. 2023.
16.	Yuuma Wada, Chie Takasu, Yuji Morine, Tetsuya Ikemoto, Yu Saitou, Shin-ichiro Yamada, Yuhei Waki, Hiroki Teraoku, Kouzou Yoshikawa, Takuya Tokunaga, Toshihiro Nakao, Masaaki Nishi, Hideya Kashihara, Toshiaki Yoshimoto and Mitsuo Shimada : 肝細胞癌におけるエクソソームmiRNAを介したLenvatinib耐性機序の検討, 第34回日本消化器癌発生学会総会, Nov. 2023.
17.	Takuya Tokunaga, Kouzou Yoshikawa, Toshihiro Nakao, Masaaki Nishi, Hideya Kashihara, Chie Takasu, Yuuma Wada, Toshiaki Yoshimoto and Mitsuo Shimada : 青色LEDはmetabolic couplingを抑制することで抗腫瘍効果をもたらす, 第34回日本消化器癌発生学会総会, Nov. 2023.
18.	Masaaki Nishi, Yuuma Wada, Kouzou Yoshikawa, Chie Takasu, Takuya Tokunaga, Toshihiro Nakao, Hideya Kashihara and Toshiaki Yoshimoto : 胃癌腹膜播種診断マーカーの臨床的有用性, 第34回日本消化器癌発生学会総会, Nov. 2023.
19.	Toshihiro Nakao, Mitsuo Shimada, Kouzou Yoshikawa, Takuya Tokunaga, Masaaki Nishi, Hideya Kashihara, Chie Takasu, Yuuma Wada and Toshiaki Yoshimoto : 大腸癌におけるImmunoscoreとフレイルの予後に与える影響, 第34回日本消化器癌発生学会総会, Nov. 2023.
20.	Toshiaki Yoshimoto, Kouzou Yoshikawa, Takuya Tokunaga, Toshihiro Nakao, Masaaki Nishi, Hideya Kashihara, Chie Takasu, Yuuma Wada and Mitsuo Shimada : 青色LED光による大腸癌の光受容体をターゲットとした治療法の開発, 第85回日本臨床外科学会総会, Nov. 2023.
21.	Yuuma Wada, Masaaki Nishi, Kouzou Yoshikawa, Chie Takasu, Takuya Tokunaga, Toshihiro Nakao, Hideya Kashihara, Toshiaki Yoshimoto and Mitsuo Shimada : 腹腔鏡下胃癌手術のトレーニングプログラム, 第85回日本臨床外科学会総会, Nov. 2023.
22.	Masaaki Nishi, Mitsuo Shimada, Kouzou Yoshikawa, Chie Takasu, Yuuma Wada, Takuya Tokunaga, Toshihiro Nakao, Hideya Kashihara and Toshiaki Yoshimoto : 食道胃接合部腺癌に対するロボット手術(経裂孔)の有用性, 第85回日本臨床外科学会総会, Nov. 2023.
23.	Hideya Kashihara, Mitsuo Shimada, Kouzou Yoshikawa, Takuya Tokunaga, Toshihiro Nakao, Masaaki Nishi, Chie Takasu, Yuuma Wada and Toshiaki Yoshimoto : 右側結腸癌に対するロボット支援下手術の可能性∼腹腔鏡手術との比較から∼, 第85回日本臨床外科学会総会, Nov. 2023.
24.	Takuya Tokunaga, Mitsuo Shimada, Kouzou Yoshikawa, Toshihiro Nakao, Masaaki Nishi, Hideya Kashihara, Chie Takasu, Yuuma Wada and Toshiaki Yoshimoto : 経肛門アプローチを併用したロボット支援下直腸切除術の有用性, 第85回日本臨床外科学会総会, Nov. 2023.
25.	Chie Takasu, Masaaki Nishi, Kouzou Yoshikawa, Takuya Tokunaga, Toshihiro Nakao, Hideya Kashihara, Yuuma Wada, Toshiaki Yoshimoto and Mitsuo Shimada : 上部胃癌に対するロボット支援手術の工夫と成績, 第85回日本臨床外科学会総会, Nov. 2023.
26.	Toshihiro Nakao, Mitsuo Shimada, Kouzou Yoshikawa, Takuya Tokunaga, Masaaki Nishi, Hideya Kashihara, Chie Takasu, Yuuma Wada and Toshiaki Yoshimoto : 直腸癌手術におけるMRIを用いた骨盤神経描出, 第85回日本臨床外科学会総会, Nov. 2023.
27.	Hideya Kashihara, Takuya Tokunaga, Mitsuo Shimada, Kouzou Yoshikawa, Toshihiro Nakao, Masaaki Nishi, Chie Takasu, Yuuma Wada and Toshiaki Yoshimoto : 他臓器浸潤を伴う直腸癌に対する経肛門アプローチの有用性, 第61回日本癌治療学会学術集会, Oct. 2023.
28.	Kouzou Yoshikawa, Mitsuo Shimada, Takuya Tokunaga, Toshihiro Nakao, Masaaki Nishi, Chie Takasu, Hideya Kashihara, Yuuma Wada and Toshiaki Yoshimoto : 腹腔鏡下胃癌手術における術前栄養リハビリ介入の有用性, 第61回日本癌治療学会学術集会, Oct. 2023.
29.	Yuuma Wada, Masaaki Nishi, Kouzou Yoshikawa, Chie Takasu, Takuya Tokunaga, Toshihiro Nakao, Hideya Kashihara, Toshiaki Yoshimoto and Mitsuo Shimada : 胃癌腹膜播種特異的なエクソソーム中miRNAの同定, 第82回日本癌学会学術総会, Sep. 2023.
30.	Masaaki Nishi, Mitsuo Shimada, Kouzou Yoshikawa, Takuya Tokunaga, Toshihiro Nakao, Chie Takasu, Hideya Kashihara, Yuuma Wada and Toshiaki Yoshimoto : 上部胃癌に対するロボット支援胃癌手術の定型化-Left-handed LCS and pincer approach-, 第98回中国四国外科学会総会第28回中国四国内視鏡外科研究会, Sep. 2023.
31.	Hideya Kashihara, Mitsuo Shimada, Kouzou Yoshikawa, Takuya Tokunaga, Toshihiro Nakao, Masaaki Nishi, Chie Takasu, Yuuma Wada and Toshiaki Yoshimoto : 腸内細菌叢の変化からみた減量・代謝改善手術の効果, 第98回中国四国外科学会総会第28回中国四国内視鏡外科研究会, Sep. 2023.
32.	Kouzou Yoshikawa, Mitsuo Shimada, Yuji Morine, Takuya Tokunaga, Toshihiro Nakao, Masaaki Nishi, Chie Takasu, Hideya Kashihara, Yuuma Wada and Toshiaki Yoshimoto : 大建中湯の消化器疾患における役割, 第98回中国四国外科学会総会第28回中国四国内視鏡外科研究会, Sep. 2023.
33.	Toshiaki Yoshimoto, Masaaki Nishi, Kouzou Yoshikawa, Toshihiro Nakao, Takuya Tokunaga, Hideya Kashihara, Chie Takasu, Yuuma Wada and Mitsuo Shimada : 青色LEDによる大腸癌由来CAF制御および抗腫瘍効果, 第78回日本消化器外科学会総会, Jul. 2023.
34.	Yuuma Wada, Masaaki Nishi, Kouzou Yoshikawa, Chie Takasu, Takuya Tokunaga, Toshihiro Nakao, Hideya Kashihara, Toshiaki Yoshimoto and Mitsuo Shimada : エクソソームmiRNAを用いた胃癌腹膜播種の予測, 第78回日本消化器外科学会総会, Jul. 2023.
35.	Toshihiro Nakao, Mitsuo Shimada, Kouzou Yoshikawa, Takuya Tokunaga, Masaaki Nishi, Hideya Kashihara, Chie Takasu, Yuuma Wada and Toshiaki Yoshimoto : 直腸癌手術におけるMRIを用いた骨盤神経描出, 第78回日本消化器外科学会総会, Jul. 2023.
36.	Hideya Kashihara, Mitsuo Shimada, Kouzou Yoshikawa, Takuya Tokunaga, Toshihiro Nakao, Masaaki Nishi, Chie Takasu, Yuuma Wada and Toshiaki Yoshimoto : 腹腔鏡下スリーブ状胃切除術後長期効果に影響を及ぼす因子に関する検討, 第78回日本消化器外科学会総会, Jul. 2023.
37.	Chie Takasu, Masaaki Nishi, Yuuma Wada, Kouzou Yoshikawa, Takuya Tokunaga, Toshihiro Nakao, Hideya Kashihara, Toshiaki Yoshimoto and Mitsuo Shimada : 高齢者フレイル胃癌患者における術前栄養・運動介入の意義:短期成績を改善するが長期成績には寄与しない, 第78回日本消化器外科学会総会, Jul. 2023.
38.	Kouzou Yoshikawa, Mitsuo Shimada, Takuya Tokunaga, Toshihiro Nakao, Masaaki Nishi, Chie Takasu, Hideya Kashihara, Yuuma Wada and Toshiaki Yoshimoto : 胃全摘出術における術後パスの有用性―PSMによる解析―, 第78回日本消化器外科学会総会, Jul. 2023.
39.	Masaaki Nishi, Mitsuo Shimada, Kouzou Yoshikawa, Chie Takasu, Yuuma Wada, Takuya Tokunaga, Toshihiro Nakao, Hideya Kashihara and Toshiaki Yoshimoto : 進行胃癌に対するロボット支援手術の有用性, 第78回日本消化器外科学会総会, Jul. 2023.
40.	Takuya Tokunaga, 杉本真樹, Kouzou Yoshikawa, Toshihiro Nakao, Masaaki Nishi, Hideya Kashihara, Chie Takasu, Yuuma Wada, Toshiaki Yoshimoto and Mitsuo Shimada : 経肛門アプローチを用いた拡大骨盤手術手技, 第78回日本消化器外科学会総会, Jul. 2023.
41.	Toshiaki Yoshimoto, Kouzou Yoshikawa, Takuya Tokunaga, Toshihiro Nakao, Masaaki Nishi, Hideya Kashihara, Chie Takasu, Yuuma Wada and Mitsuo Shimada : 大腸癌におけるFrailの意義と免疫栄養指標との関連, 日本外科代謝栄養学会第60回学術集会, Jul. 2023.
42.	Yuuma Wada, Masaaki Nishi, Kouzou Yoshikawa, Chie Takasu, Takuya Tokunaga, Toshihiro Nakao, Hideya Kashihara, Toshiaki Yoshimoto and Mitsuo Shimada : 胃癌術前における栄養，リハビリ介入の検討, 日本外科代謝栄養学会第60回学術集会, Jul. 2023.
43.	Takayuki Noma, Masaaki Nishi, Kouzou Yoshikawa, Chie Takasu, Yuuma Wada, Takuya Tokunaga, Toshihiro Nakao, Hideya Kashihara, Toshiaki Yoshimoto and Mitsuo Shimada : 切除不能進行胃癌に対してSOX-NIVO後Conversion手術を施行した2症例, 第44回癌免疫外科研究会, Jun. 2023.
44.	Chie Takasu, Kouzou Yoshikawa, Takuya Tokunaga, Toshihiro Nakao, Masaaki Nishi, Hideya Kashihara, Yuuma Wada, Toshiaki Yoshimoto and Mitsuo Shimada : 女性消化器外科医の技術向上とキャリア育成を目指した取り組み, 日本消化器病学会四国支部第119回例会, Jun. 2023.
45.	Toshihiro Nakao, Mitsuo Shimada, Kouzou Yoshikawa, Takuya Tokunaga, Masaaki Nishi, Hideya Kashihara, Chie Takasu, Yuuma Wada and Toshiaki Yoshimoto : The Correlation of Immunoscore and Frailty in Colorectal Cancer, 第48回日本外科系連合学会学術集会, Jun. 2023.
46.	Kouzou Yoshikawa, Mitsuo Shimada, Takuya Tokunaga, Toshihiro Nakao, Masaaki Nishi, Hideya Kashihara, Chie Takasu, Yuuma Wada and Toshiaki Yoshimoto : 腹腔鏡下スリーブ状胃切除における多職種介入周術期管理の有用性, 第48回日本外科系連合学会学術集会, Jun. 2023.
47.	Masaaki Nishi, Mitsuo Shimada, Kouzou Yoshikawa, Chie Takasu, Yuuma Wada, Takuya Tokunaga, Toshihiro Nakao, Hideya Kashihara and Toshiaki Yoshimoto : 食道胃接合部腺癌に対するロボット支援下手術(経裂孔)の有用性, 第32回日本癌病態治療研究会, Jun. 2023.
48.	Masaaki Nishi, Mitsuo Shimada, Kouzou Yoshikawa, Chie Takasu, Yuuma Wada, Takuya Tokunaga, Toshihiro Nakao, Hideya Kashihara and Toshiaki Yoshimoto : 上部胃癌・食道胃接合部癌に対するロボット支援胃癌手術の手術手技, 第77回手術手技研究会, May 2023.
49.	仲須千春, Masaaki Nishi, Yuji Morine, Toshiaki Yoshimoto, Kouzou Yoshikawa, Takuya Tokunaga, Toshihiro Nakao, Chie Takasu, Hideya Kashihara, Yuuma Wada and Mitsuo Shimada : 青色LEDを用いたCAFの糖代謝に着目した腫瘍免疫制御のメカニズムの解明, 第123回日本外科学会定期学術集会, Apr. 2023.
50.	Chie Takasu, Masaaki Nishi, Yuuma Wada, Kouzou Yoshikawa, Takuya Tokunaga, Toshihiro Nakao, Hideya Kashihara, Toshiaki Yoshimoto and Mitsuo Shimada : 高齢者フレイル胃癌患者における術前栄養・運動リハビリの意義: 短期成績を改善するが長期成績には寄与しない, 第123回日本外科学会定期学術集会, Apr. 2023.
51.	Yuuma Wada, Masaaki Nishi, Kouzou Yoshikawa, Takuya Tokunaga, Toshihiro Nakao, Hideya Kashihara, Toshiaki Yoshimoto and Mitsuo Shimada : 胃癌フレイル患者における術前栄養リハビリ介入の有用性, 第123回日本外科学会定期学術集会, Apr. 2023.
52.	Hideya Kashihara, Mitsuo Shimada, Kouzou Yoshikawa, Takuya Tokunaga, Toshihiro Nakao, Masaaki Nishi, Chie Takasu, Yuuma Wada and Toshiaki Yoshimoto : 腸脳相関からみたMetabolic surgeryの術後早期血糖抑制効果, 第123回日本外科学会定期学術集会, Apr. 2023.
53.	Masaaki Nishi, Mitsuo Shimada, Kouzou Yoshikawa, Chie Takasu, Yuuma Wada, Takuya Tokunaga, Toshihiro Nakao, Hideya Kashihara and Toshiaki Yoshimoto : Utility of robotic surgery for Siewert type II/III adenocarcinoma of esophagogastric junction: transhiatal robotic versus laparoscopic approach, 第123回日本外科学会定期学術集会, Apr. 2023.
54.	Takuya Tokunaga, 杉本真樹, Kouzou Yoshikawa, Toshihiro Nakao, Masaaki Nishi, Hideya Kashihara, Chie Takasu, Yuuma Wada, Toshiaki Yoshimoto, 髙橋叡 and Mitsuo Shimada : 下部直腸癌に対する経肛門アプローチにおける術中ホログラム手術支援の有用性, 第123回日本外科学会定期学術集会, Apr. 2023.
55.	Toshiaki Yoshimoto, Shohei Okikawa, Kouzou Yoshikawa, Toshihiro Nakao, Takuya Tokunaga, Masaaki Nishi, Hideya Kashihara, Chie Takasu, Yuuma Wada and Mitsuo Shimada : 青色LED光の腫瘍微小環境に対する効果, 第123回日本外科学会定期学術集会, Apr. 2023.
56.	Toshihiro Nakao, Mitsuo Shimada, Kouzou Yoshikawa, Takuya Tokunaga, Masaaki Nishi, Hideya Kashihara, Chie Takasu, Yuuma Wada and Toshiaki Yoshimoto : 直腸癌に対するMRIを用いた骨盤神経描出, 第123回日本外科学会定期学術集会, Apr. 2023.
57.	Takuya Tokunaga, Yu Saitou, 杉本真樹, Kouzou Yoshikawa, Toshihiro Nakao, Masaaki Nishi, Hideya Kashihara, Chie Takasu, Yuuma Wada, Toshiaki Yoshimoto, 山下祥子, 岩川陽介 and Mitsuo Shimada : 経肛門アプローチを用いた腹腔鏡下側方郭清の手術手技と短期成績 ∼Hologramによるシミュレーションの有用性∼, 第122回日本外科学会定期学術集会, Apr. 2023.
58.	Yuuma Wada, Masaaki Nishi, Kouzou Yoshikawa, Chie Takasu, Takuya Tokunaga, Toshihiro Nakao, Hideya Kashihara and Mitsuo Shimada : 胃癌手術における術前栄養リハビリ介入の有用性, 第95回日本胃癌学会総会, Feb. 2023.
59.	Masaaki Nishi, Mitsuo Shimada, Kouzou Yoshikawa, Chie Takasu, Yuuma Wada, Takuya Tokunaga, Toshihiro Nakao, Hideya Kashihara and Toshiaki Yoshimoto : 上部胃癌・食道胃接合部癌に対するロボット手術の有用性, 第95回日本胃癌学会総会, Feb. 2023.
60.	Chie Takasu, Masaaki Nishi, Yuuma Wada, Kouzou Yoshikawa, Takuya Tokunaga, Toshihiro Nakao, Hideya Kashihara, Toshiaki Yoshimoto and Mitsuo Shimada : 高齢者フレイル胃癌患者における術前栄養・運動介入の意義:短期成績を改善するが長期成績には寄与しない, 第95回日本胃癌学会総会, Feb. 2023.
61.	Kouzou Yoshikawa, Mitsuo Shimada, Takuya Tokunaga, Toshihiro Nakao, Masaaki Nishi, Hideya Kashihara, Chie Takasu, Yuuma Wada and Toshiaki Yoshimoto : MISによる胃全摘OrVil法におけるピットフォールとトラブルシューティング, 第95回日本胃癌学会総会, Feb. 2023.
62.	Takuya Tokunaga, Mitsuo Shimada, Kouzou Yoshikawa, Toshihiro Nakao, Masaaki Nishi, Hideya Kashihara, Chie Takasu, Yuuma Wada and Toshiaki Yoshimoto : 下部直腸癌に対するホログラムを駆使した新たな経肛門手術, 第266回徳島医学会学術集会, Feb. 2023.
63.	Toshiaki Yoshimoto, Kouzou Yoshikawa, Takuya Tokunaga, Toshihiro Nakao, Masaaki Nishi, Hideya Kashihara, Chie Takasu, Yuuma Wada and Mitsuo Shimada : ロボット支援前立腺全摘後に発症した鼠径ヘルニアに対する腹腔鏡手術症例の検討, 第35回日本内視鏡外科学会総会, Dec. 2022.
64.	Hideya Kashihara, Mitsuo Shimada, Kouzou Yoshikawa, Takuya Tokunaga, Toshihiro Nakao, Masaaki Nishi, Chie Takasu, Yuuma Wada and Toshiaki Yoshimoto : 直腸癌に対するTaTME併用ロボット支援下直腸切除術(Hybrid robotic surgery)の有用性, 第35回日本内視鏡外科学会総会, Dec. 2022.
65.	Takuya Tokunaga, Mitsuo Shimada, Kouzou Yoshikawa, Toshihiro Nakao, Masaaki Nishi, Hideya Kashihara, Chie Takasu, Yuuma Wada and Toshiaki Yoshimoto : 経肛門側方リンパ節郭清の手技と短期成績 ∼ホログラムシミュレーションの有用性∼, 第35回日本内視鏡外科学会総会, Dec. 2022.
66.	Chie Takasu, Kouzou Yoshikawa, Takuya Tokunaga, Toshihiro Nakao, Masaaki Nishi, Hideya Kashihara, Yuuma Wada, Toshiaki Yoshimoto and Mitsuo Shimada : 腹腔鏡下胃切除における6番リンパ節郭清困難性の術前予測, 第35回日本内視鏡外科学会総会, Dec. 2022.
67.	Masaaki Nishi, Mitsuo Shimada, Kouzou Yoshikawa, Takuya Tokunaga, Toshihiro Nakao, Chie Takasu, Hideya Kashihara, Yuuma Wada and Toshiaki Yoshimoto : 食道胃接合部癌に対するロボット支援下手術(経裂孔)の工夫, 第35回日本内視鏡外科学会総会, Dec. 2022.
68.	Kouzou Yoshikawa, Mitsuo Shimada, Takuya Tokunaga, Toshihiro Nakao, Masaaki Nishi, Hideya Kashihara, Chie Takasu, Yuuma Wada and Toshiaki Yoshimoto : 低侵襲胃全摘術後再建における肝臓脱転による視野確保とOrVil法の有用性, 第35回日本内視鏡外科学会総会, Dec. 2022.
69.	Toshiaki Yoshimoto, Kouzou Yoshikawa, Takuya Tokunaga, Toshihiro Nakao, Masaaki Nishi, Hideya Kashihara, Chie Takasu, Yuuma Wada, 髙橋叡 and Mitsuo Shimada : DST吻合における吻合部血流不全のリスク因子および追加切除例の検討, 第84回日本臨床外科学会総会, Nov. 2022.
70.	Yuuma Wada, Masaaki Nishi, Mitsuo Shimada, Kouzou Yoshikawa, Takuya Tokunaga, Toshihiro Nakao, Chie Takasu, Hideya Kashihara and Toshiaki Yoshimoto : 局所進行直腸癌に対する術前化学放射線療法におけるADC値の有用性, 第84回日本臨床外科学会総会, Nov. 2022.
71.	Hideya Kashihara, Mitsuo Shimada, Kouzou Yoshikawa, Takuya Tokunaga, Toshihiro Nakao, Masaaki Nishi, Chie Takasu, Yuuma Wada and Toshiaki Yoshimoto : 直腸癌に対するTaTME併用ロボット支援下直腸切除術(Hybrid robotic surgery)の有用性, 第84回日本臨床外科学会総会, Nov. 2022.
72.	Toshihiro Nakao, Kouzou Yoshikawa, Takuya Tokunaga, Masaaki Nishi, Hideya Kashihara, Chie Takasu, Yuuma Wada and Toshiaki Yoshimoto : 腹腔鏡下結腸癌手術における体腔内吻合の短期成績, 第84回日本臨床外科学会総会, Nov. 2022.
73.	Kouzou Yoshikawa, Mitsuo Shimada, Takuya Tokunaga, Toshihiro Nakao, Masaaki Nishi, Hideya Kashihara, Chie Takasu, Yuuma Wada and Toshiaki Yoshimoto : 胃全摘出術における術後パスの有用性―PSMによる解析―, 第84回日本臨床外科学会総会, Nov. 2022.
74.	Masaaki Nishi, Mitsuo Shimada, Kouzou Yoshikawa, Chie Takasu, Takuya Tokunaga, Toshihiro Nakao, Yuuma Wada, Hideya Kashihara and Toshiaki Yoshimoto : 上部胃癌に対するロボット支援胃癌手術の定型化- Left-handed LCS and pincer app roach –, 第84回日本臨床外科学会総会, Nov. 2022.
75.	Takuya Tokunaga, Mitsuo Shimada, Kouzou Yoshikawa, Toshihiro Nakao, Masaaki Nishi, Hideya Kashihara, Chie Takasu, Yuuma Wada, Toshiaki Yoshimoto and 髙橋叡 : 他臓器浸潤を伴う直腸癌に対する経肛門アプローチの有用性, 第84回日本臨床外科学会総会, Nov. 2022.
76.	Hideya Kashihara, Mitsuo Shimada, Kouzou Yoshikawa, Takuya Tokunaga, Toshihiro Nakao, Masaaki Nishi, Chie Takasu, Yuuma Wada and Toshiaki Yoshimoto : 直腸癌に対するTaTME併用ロボット支援下直腸切除術(Hybrid robotic surgery)の有用性, 第118回日本消化器病学会四国支部例会, Nov. 2022.
77.	Kouzou Yoshikawa, Mitsuo Shimada, Masaaki Nishi, Takuya Tokunaga, Toshihiro Nakao, Chie Takasu, Hideya Kashihara, Yuuma Wada and Toshiaki Yoshimoto : 腹腔鏡下胃癌手術における術前栄養リハビリ介入の有用性, 第52回胃外科・術後障害研究会, Nov. 2022.
78.	Masaaki Nishi, 陳術海, Yuji Morine, Kouzou Yoshikawa, Takuya Tokunaga, Toshihiro Nakao, Hideya Kashihara, Chie Takasu, Yuuma Wada, Toshiaki Yoshimoto and Mitsuo Shimada : CAFの糖代謝を標的とした治療法の開発 -フラボノイド(EGCGとSudachitin)の可能性-, 第33回日本消化器癌発生学会総会, Nov. 2022.
79.	Takuya Tokunaga, Toshiaki Yoshimoto, Kouzou Yoshikawa, Toshihiro Nakao, Masaaki Nishi, Hideya Kashihara, Chie Takasu, Yuuma Wada, 髙橋叡 and Mitsuo Shimada : 腫瘍関連マクロファージおよび大腸癌に対する青色LEDの効果, 第33回日本消化器癌発生学会総会, Nov. 2022.
80.	Toshihiro Nakao, Mitsuo Shimada, Kouzou Yoshikawa, Takuya Tokunaga, Masaaki Nishi, Hideya Kashihara, Chie Takasu, Yuuma Wada and Toshiaki Yoshimoto : 大腸癌におけるImmunoscoreとFrailの相関についての検討, 第33回日本消化器癌発生学会総会, Nov. 2022.
81.	Masaaki Nishi, Chie Takasu, Yuji Morine, Kouzou Yoshikawa, Takuya Tokunaga, Yuuma Wada, Toshihiro Nakao, Hideya Kashihara, Toshiaki Yoshimoto and Mitsuo Shimada : 漢方とBacterial translocation-大建中湯の消化管疾患に対する多面的効果の検討-, 第35回日本外科感染症学会総会学術集会, Nov. 2022.
82.	Toshiaki Yoshimoto, Kouzou Yoshikawa, Toshihiro Nakao, Takuya Tokunaga, Masaaki Nishi, Hideya Kashihara, Chie Takasu, Yuuma Wada, 髙橋叡 and Mitsuo Shimada : 大腸癌手術における予後因子としてのFrailの意義, 第60回日本癌治療学会学術集会, Oct. 2022.
83.	Hideya Kashihara, Mitsuo Shimada, Kouzou Yoshikawa, Takuya Tokunaga, Toshihiro Nakao, Masaaki Nishi, Chie Takasu, Yuuma Wada and Toshiaki Yoshimoto : 下部直腸癌に対するTaTME併用ロボット支援下直腸切除術の有用性, 第60回日本癌治療学会学術集会, Oct. 2022.
84.	Masaaki Nishi, Mitsuo Shimada, Kouzou Yoshikawa, Chie Takasu, Takuya Tokunaga, Toshihiro Nakao, Hideya Kashihara, Yuuma Wada and Toshiaki Yoshimoto : 上部胃癌に対するロボット手術の工夫 Pincer approach to gastrosplenic ligament, 第60回日本癌治療学会学術集会, Oct. 2022.
85.	Takuya Tokunaga, Kouzou Yoshikawa, Toshihiro Nakao, Masaaki Nishi, Hideya Kashihara, Chie Takasu, Yuuma Wada, Toshiaki Yoshimoto, 髙橋叡 and Mitsuo Shimada : ハイブリッド側方リンパ節郭清手技と短期成績∼ホログラムシミュレーションの有用性∼, 第60回日本癌治療学会学術集会, Oct. 2022.
86.	Yuuma Wada, Mitsuo Shimada, Masaaki Nishi, Kouzou Yoshikawa, Takuya Tokunaga, Toshihiro Nakao, Chie Takasu, Hideya Kashihara and Toshiaki Yoshimoto : 局所進行直腸癌における術前化学放射線療法においてADC値の有用性, 第60回日本癌治療学会学術集会, Oct. 2022.
87.	Toshihiro Nakao, Mitsuo Shimada, Kouzou Yoshikawa, Takuya Tokunaga, Masaaki Nishi, Hideya Kashihara, Chie Takasu, Yuuma Wada, Toshiaki Yoshimoto and 髙橋叡 : 大腸癌におけるImmunosoreとFrailの相関, 第60回日本癌治療学会学術集会, Oct. 2022.
88.	Kouzou Yoshikawa, Mitsuo Shimada, Takuya Tokunaga, Toshihiro Nakao, Masaaki Nishi, Hideya Kashihara, Chie Takasu, Yuuma Wada and Toshiaki Yoshimoto : 胃全摘出術における術後パスの有用性―PSMによる解析―, 第60回日本癌治療学会学術集会, Oct. 2022.
89.	Hideya Kashihara, Takuya Tokunaga, Mitsuo Shimada, Kouzou Yoshikawa, Toshihiro Nakao, Chie Takasu, Yuuma Wada and Toshiaki Yoshimoto : 下部直腸癌に対するTaTME併用ロボット支援下直腸切除術(Hybrid robotic surgery)の有用性, 第77回日本大腸肛門病学会学術集会, Oct. 2022.
90.	Takuya Tokunaga, Mitsuo Shimada, Kouzou Yoshikawa, Toshihiro Nakao, Masaaki Nishi, Hideya Kashihara, Chie Takasu, Yuuma Wada, Toshiaki Yoshimoto and 髙橋叡 : 他臓器浸潤直腸癌に対するTpAPR手術手技, 第77回日本大腸肛門病学会学術集会, Oct. 2022.
91.	Yuuma Wada, Masaaki Nishi, Yuji Morine, Kouzou Yoshikawa, Takuya Tokunaga, Toshihiro Nakao, Chie Takasu, Hideya Kashihara, Toshiaki Yoshimoto and Mitsuo Shimada : 癌関連線維芽細胞における糖代謝に着目した治療法の可能性, 第81回日本癌学会学術総会, Sep. 2022.
92.	Hideya Kashihara, Mitsuo Shimada, Kouzou Yoshikawa, Takuya Tokunaga, Toshihiro Nakao, Masaaki Nishi, Chie Takasu, Yuuma Wada and Toshiaki Yoshimoto : 下部直腸癌に対するTaTME併用ロボット支援下直腸切除術(Hybrid robotic surgery)の有用性, 第97回中国四国外科学会総会/第27回中国四国内視鏡外科研究会, Sep. 2022.
93.	Masaaki Nishi, Mitsuo Shimada, Kouzou Yoshikawa, Yuuma Wada, Chie Takasu, Takuya Tokunaga, Toshihiro Nakao, Hideya Kashihara and Toshiaki Yoshimoto : 上部胃癌におけるロボット支援胃癌手術の工夫, 第97回中国四国外科学会総会/第27回中国四国内視鏡外科研究会, Sep. 2022.
94.	Chie Takasu, Kouzou Yoshikawa, Toshihiro Nakao, Masaaki Nishi, Takuya Tokunaga, Hideya Kashihara, Yuuma Wada, Toshiaki Yoshimoto, 髙橋叡 and Mitsuo Shimada : 腹腔鏡下胃切除における幽門下リンパ郭清困難性の術前評価, 第97回中国四国外科学会総会/第27回中国四国内視鏡外科研究会, Sep. 2022.
95.	Toshihiro Nakao, Mitsuo Shimada, Kouzou Yoshikawa, Takuya Tokunaga, Masaaki Nishi, Hideya Kashihara, Chie Takasu, Yuuma Wada and Toshiaki Yoshimoto : 腹腔鏡下結腸癌手術における体腔内吻合の短期成績, 第97回中国四国外科学会総会/第27回中国四国内視鏡外科研究会, Sep. 2022.
96.	Masaaki Nishi, Shuhai Chen, Yuji Morine, Kouzou Yoshikawa, Takuya Tokunaga, Toshihiro Nakao, Hideya Kashihara, Chie Takasu, Yuuma Wada, Toshiaki Yoshimoto and Mitsuo Shimada : CAFの糖代謝を標的とした治療法の開発-フラボノイド(EGCGとSudachitin)の可能性-, 第265回徳島医学会学術集会, Jul. 2022.
97.	岩川陽介, Masaaki Nishi, Yuuma Wada, Mitsuo Shimada, Kouzou Yoshikawa, Toshihiro Nakao, Takuya Tokunaga, Chie Takasu, Hideya Kashihara and Toshiaki Yoshimoto : 胃GISTに対するLECSの検討 -腫瘍径5㎝以上に対するLECS-, 第77回日本消化器外科学会総会, Jul. 2022.
98.	Takuya Tokunaga, 杉本真樹, Kouzou Yoshikawa, Toshihiro Nakao, Masaaki Nishi, Hideya Kashihara, Chie Takasu, Yuuma Wada, Toshiaki Yoshimoto and Mitsuo Shimada : Hologramによるシミュレーションを用いた経肛門的側方リンパ節郭清, 第77回日本消化器外科学会総会, Jul. 2022.
99.	Toshiaki Yoshimoto, Kouzou Yoshikawa, Toshihiro Nakao, Takuya Tokunaga, Masaaki Nishi, Hideya Kashihara, Chie Takasu, Yuuma Wada, 沖川昌平 and Mitsuo Shimada : 大腸癌腫瘍関連マクロファージに対する青色LEDの効果, 第77回日本消化器外科学会総会, Jul. 2022.
100.	Yuuma Wada, Mitsuo Shimada, Masaaki Nishi, Kouzou Yoshikawa, Takuya Tokunaga, Toshihiro Nakao, Chie Takasu, Hideya Kashihara, Toshiaki Yoshimoto and 岩川陽介 : 腹腔鏡下胃癌手術における術前栄養リハビリ介入の有用性, 第77回日本消化器外科学会総会, Jul. 2022.
101.	Hideya Kashihara, Mitsuo Shimada, Kouzou Yoshikawa, Takuya Tokunaga, Toshihiro Nakao, Masaaki Nishi, Chie Takasu, Yuuma Wada, Toshiaki Yoshimoto and 山下祥子 : 腹腔鏡下スリーブ状胃切除術後長期効果に影響を及ぼす因子に関する検討, 第77回日本消化器外科学会総会, Jul. 2022.
102.	Masaaki Nishi, Mitsuo Shimada, Kouzou Yoshikawa, Chie Takasu, Takuya Tokunaga, Toshihiro Nakao, Hideya Kashihara, Toshiaki Yoshimoto, Yuuma Wada and 山下祥子 : 上部胃癌に対するロボット支援胃癌手術の工夫, 第77回日本消化器外科学会総会, Jul. 2022.
103.	Kouzou Yoshikawa, Mitsuo Shimada, Takuya Tokunaga, Toshihiro Nakao, Masaaki Nishi, Hideya Kashihara, Chie Takasu, Yuuma Wada, Toshiaki Yoshimoto and 山下祥子 : 胃癌播種診断におけるCTスコアリングシステムを用いた診断率改善の試み, 第77回日本消化器外科学会総会, Jul. 2022.
104.	Takuya Tokunaga, Kouzou Yoshikawa, Toshihiro Nakao, Masaaki Nishi, Hideya Kashihara, Chie Takasu, Yuuma Wada, Toshiaki Yoshimoto and Mitsuo Shimada : 直腸癌に対するTaTME併用ロボット支援下直腸切除術の有用性, 第31回日本癌病態治療研究会, Jun. 2022.
105.	Yuuma Wada, Kouzou Yoshikawa, Masaaki Nishi, Takuya Tokunaga, Toshihiro Nakao, Chie Takasu, Hideya Kashihara, Toshiaki Yoshimoto and Mitsuo Shimada : 進行胃癌に対するロボット支援下胃切除術の有用性, 第117回例会日本消化器病学会四国支部, Jun. 2022.
106.	Kouzou Yoshikawa, Mitsuo Shimada, Takuya Tokunaga, Toshihiro Nakao, Masaaki Nishi, Hideya Kashihara, Chie Takasu, Yuuma Wada, Toshiaki Yoshimoto and 山下祥子 : 進行胃癌に対するロボット支援胃切除術の有用性とピットフォール, 第47回日本外科系連合学会学術集会, Jun. 2022.
107.	Toshiaki Yoshimoto, Takuya Tokunaga, Yu Saitou, Hideya Kashihara, Kouzou Yoshikawa, Toshihiro Nakao, Masaaki Nishi, Chie Takasu, Yuuma Wada, 山下祥子, 岩川陽介 and Mitsuo Shimada : Intraoperative holographic image-guided lateral pelvic lymph node dissection in a transanal approach for rectal cancer, CARS 2022, Jun. 2022.
108.	Takuya Tokunaga, 杉本真樹, Yu Saitou, Kouzou Yoshikawa, Toshihiro Nakao, Masaaki Nishi, Hideya Kashihara, Chie Takasu, Yuuma Wada, Toshiaki Yoshimoto and Mitsuo Shimada : 経肛門アプローチ併用ハイブリッド側方リンパ節郭清に対するホログラムの有用性, 第31回日本コンピュータ外科学会大会, Jun. 2022.
109.	Yuuma Wada, Masaaki Nishi, Kouzou Yoshikawa, Takuya Tokunaga, Toshihiro Nakao, Hideya Kashihara, Chie Takasu, Toshiaki Yoshimoto and Mitsuo Shimada : Apparent diffusion coefficient measurements predict survival outcomes after neoadjuvant chemoradiotherapy in locally advanced rectal cancer, 第67回国際外科学会日本部会総会, Jun. 2022.
110.	Masaaki Nishi, Mitsuo Shimada, Kouzou Yoshikawa, Chie Takasu, Yuuma Wada, Takuya Tokunaga, Toshihiro Nakao, Hideya Kashihara and Toshiaki Yoshimoto : ロボット胃癌手術における工夫 -Left handed LCS techniqueとPincer approach for gastro-splenic ligament-, 第76回手術手技研究会, May 2022.
111.	Kouzou Yoshikawa, Mitsuo Shimada, Takuya Tokunaga, Toshihiro Nakao, Masaaki Nishi, Hideya Kashihara, Chie Takasu, Yuuma Wada and Toshiaki Yoshimoto : 術前抗がん剤治療を行った進行胃癌に対する低侵襲手術の有用性, 第122回日本外科学会定期学術集会, Apr. 2022.
112.	Takuya Tokunaga, Yu Saitou, 杉本真樹, Kouzou Yoshikawa, Toshihiro Nakao, Masaaki Nishi, Hideya Kashihara, Chie Takasu, Yuuma Wada, Toshiaki Yoshimoto, Shoko Yamashita, 岩川陽介 and Mitsuo Shimada : 経肛門アプローチを用いた腹腔鏡下側方郭清の手術手技と短期成績∼Hologramによるシミュレーションの有用性∼, 第122回日本外科学会定期学術集会, Apr. 2022.
113.	Yoshihito Matsuzaki, Masaaki Nishi, Mitsuo Shimada, Kouzou Yoshikawa, Chie Takasu, Yuuma Wada, Takuya Tokunaga, Toshihiro Nakao, Hideya Kashihara and Toshiaki Yoshimoto : ALS患者の胃癌2切除例, 第122回日本外科学会定期学術集会, Apr. 2022.
114.	Yuuma Wada, Masaaki Nishi, 陳術海, Yuji Morine, Kouzou Yoshikawa, Takuya Tokunaga, Toshihiro Nakao, Hideya Kashihara, Chie Takasu, Toshiaki Yoshimoto, 山下祥子, 岩川陽介 and Mitsuo Shimada : 癌関連線維芽細胞の糖代謝を標的とした治療法の開発, 第122回日本外科学会定期学術集会, Apr. 2022.
115.	Toshihiro Nakao, Mitsuo Shimada, Kouzou Yoshikawa, Takuya Tokunaga, Masaaki Nishi, Hideya Kashihara, Chie Takasu, Yuuma Wada, Toshiaki Yoshimoto, 山下祥子 and 岩川陽介 : 大腸癌におけるImmunoscoreとフレイルの検討, 第122回日本外科学会定期学術集会, Apr. 2022.
116.	Hideya Kashihara, Mitsuo Shimada, Kouzou Yoshikawa, Takuya Tokunaga, Toshihiro Nakao, Masaaki Nishi, Chie Takasu, Yuuma Wada and Toshiaki Yoshimoto : 直腸癌に対するTaTME併用ロボット支援下直腸切除術の有用性 - TaTME併用腹腔鏡下直腸切除術との比較から –, 第122回日本外科学会定期学術集会, Apr. 2022.
117.	武原悠花子, Mitsuo Shimada, Kouzou Yoshikawa, Takuya Tokunaga, Toshihiro Nakao, Masaaki Nishi, Chie Takasu, Hideya Kashihara, Yuuma Wada and Toshiaki Yoshimoto : 腹腔鏡下スリーブ状胃切除における多職種介入術前減量プログラムの有用, 第122回日本外科学会定期学術集会, Apr. 2022.
118.	山下祥子, Masaaki Nishi, Mitsuo Shimada, Kouzou Yoshikawa, Takuya Tokunaga, Toshihiro Nakao, Hideya Kashihara, Chie Takasu, Yuuma Wada, Toshiaki Yoshimoto and 岩川陽介 : 直腸癌の放射線化学療法における肥満細胞の役割, 第122回日本外科学会定期学術集会, Apr. 2022.
119.	沖川昌平, Hideya Kashihara, Mitsuo Shimada, Kouzou Yoshikawa, Toshihiro Nakao, Masaaki Nishi, Chie Takasu, Yuuma Wada, Toshiaki Yoshimoto, 山下祥子 and Yuji Morine : Duodenal-jejunal bypassの術後早期血糖抑制効果に関する検討, 第122回日本外科学会定期学術集会, Apr. 2022.
120.	Masaaki Nishi, Mitsuo Shimada, Kouzou Yoshikawa, Chie Takasu, Yuuma Wada, Takuya Tokunaga, Toshihiro Nakao, Hideya Kashihara, Toshiaki Yoshimoto and 山下祥子 : ロボット支援胃癌手術の短期・長期成績-ロボットvs腹腔鏡:プロペンシティスコアマッチ解析-, 第122回日本外科学会定期学術集会, Apr. 2022.
121.	Chie Takasu, Kouzou Yoshikawa, Toshihiro Nakao, Masaaki Nishi, Takuya Tokunaga, Hideya Kashihara, Yuuma Wada, Toshiaki Yoshimoto and Shoko Yamashita : 腹腔鏡下胃切除における幽門下リンパ郭清困難性の術前評価, 第94回日本胃癌学会総会, Mar. 2022.
122.	Yuuma Wada, Masaaki Nishi, Mitsuo Shimada, Kouzou Yoshikawa, Chie Takasu, Takuya Tokunaga, Toshihiro Nakao, Hideya Kashihara, Toshiaki Yoshimoto, Shoko Yamashita and IWAKAWA Yosuke : 高齢者におけるFrailtyの臨床的意義, 第94回日本胃癌学会総会, Mar. 2022.
123.	Masaaki Nishi, Mitsuo Shimada, Kouzou Yoshikawa, Chie Takasu, Yuuma Wada, Takuya Tokunaga, Toshihiro Nakao, Hideya Kashihara, Toshiaki Yoshimoto and Shoko Yamashita : Propensity score-matched analysis of the short-and long-term outcomes of RG vs. LG, 第94回日本胃癌学会総会, Mar. 2022.
124.	Kouzou Yoshikawa, Mitsuo Shimada, Takuya Tokunaga, Toshihiro Nakao, Masaaki Nishi, Chie Takasu, Hideya Kashihara, Yuuma Wada, Toshiaki Yoshimoto and Shoko Yamashita : The usefulness of the minimal invasive surgery for advanced gastric cancer with preoperative chemotherapy, 第94回日本胃癌学会総会, Mar. 2022.
125.	Chie Takasu, Yuji Morine, Kouzou Yoshikawa, Toshihiro Nakao, Masaaki Nishi, Takuya Tokunaga, Hideya Kashihara, Yuuma Wada, Toshiaki Yoshimoto and Mitsuo Shimada : 腸管Microbiome解析からみた大建中湯の消化管疾患に対する多面的効果の検討, 第18回日本消化管学会総会学術集会(GI Week 2022), Feb. 2022.
126.	Toshiaki Yoshimoto, Kouzou Yoshikawa, Takuya Tokunaga, Toshihiro Nakao, Masaaki Nishi, Hideya Kashihara, Chie Takasu, Yuuma Wada, Shoko Yamashita, IWAKAWA Yosuke and Mitsuo Shimada : ロボット支援下前立腺全摘術後に発症した鼠径ヘルニアの検討, 第34回日本内視鏡外科学会総会, Dec. 2021.
127.	Yuuma Wada, Masaaki Nishi, Mitsuo Shimada, Kouzou Yoshikawa, Takuya Tokunaga, Toshihiro Nakao, Chie Takasu, Hideya Kashihara, Toshiaki Yoshimoto, Shoko Yamashita and IWAKAWA Yosuke : 腹腔鏡・ロボット支援下胃癌手術のトレーニングプログラムの構築, 第34回日本内視鏡外科学会総会, Dec. 2021.
128.	Chie Takasu, Kouzou Yoshikawa, Toshihiro Nakao, Takuya Tokunaga, Hideya Kashihara, Yuuma Wada, Toshiaki Yoshimoto, Shoko Yamashita and Mitsuo Shimada : 腹腔鏡下胃切除における幽門下リンパ郭清困難性の術前評価, 第34回日本内視鏡外科学会総会, Dec. 2021.
129.	Hideya Kashihara, Mitsuo Shimada, Kouzou Yoshikawa, Takuya Tokunaga, Toshihiro Nakao, Masaaki Nishi, Chie Takasu, Yuuma Wada and Toshiaki Yoshimoto : NASHに対する新たな治療アプローチとしての腹腔鏡下スリーブ状胃切除術, 第34回日本内視鏡外科学会総会, Dec. 2021.
130.	Masaaki Nishi, Mitsuo Shimada, Kouzou Yoshikawa, Takuya Tokunaga, Toshihiro Nakao, Hideya Kashihara, Chie Takasu, Yuuma Wada, Toshiaki Yoshimoto, Shoko Yamashita and IWAKAWA Yosuke : ロボット支援胃癌手術の有用性, 第34回日本内視鏡外科学会総会, Dec. 2021.
131.	Toshihiro Nakao, Mitsuo Shimada, Kouzou Yoshikawa, Takuya Tokunaga, Masaaki Nishi, Hideya Kashihara, Chie Takasu, Yuuma Wada, Toshiaki Yoshimoto, Shoko Yamashita and IWAKAWA Yosuke : 横行結腸・脾弯曲部・下行結腸癌における血管走行と腹腔鏡下手術手技に関する検討, 第34回日本内視鏡外科学会総会, Dec. 2021.
132.	Takuya Tokunaga, Mitsuo Shimada, Kouzou Yoshikawa, Toshihiro Nakao, Masaaki Nishi, Hideya Kashihara, Chie Takasu, Yuuma Wada, Toshiaki Yoshimoto, Shoko Yamashita and IWAKAWA Yosuke : 他臓器合併切除を要する直腸癌に対するTrasaperineal abdominoperineal resection, 第34回日本内視鏡外科学会総会, Dec. 2021.
133.	Kouzou Yoshikawa, Mitsuo Shimada, Takuya Tokunaga, Toshihiro Nakao, Masaaki Nishi, Hideya Kashihara, Chie Takasu, Yuuma Wada and Toshiaki Yoshimoto : 腹腔鏡下スリーブ状胃切除における多職種介入周術期管理の有用性(WS5-2), 第34回日本内視鏡外科学会総会, Dec. 2021.
134.	Kouzou Yoshikawa, Mitsuo Shimada, Toshihiro Nakao, Takuya Tokunaga, Masaaki Nishi, Chie Takasu, Hideya Kashihara, Yuuma Wada and Toshiaki Yoshimoto : ロボット支援胃癌手術におけるLeft hand LCS techniqueを用いた定型化への取り組み(WS6-7), 第34回日本内視鏡外科学会総会, Dec. 2021.
135.	Toshiaki Yoshimoto, Shohei Okikawa, Kouzou Yoshikawa, Takuya Tokunaga, Toshihiro Nakao, Masaaki Nishi, Hideya Kashihara, Chie Takasu, Yuuma Wada, Shoko Yamashita, IWAKAWA Yosuke and Mitsuo Shimada : 青色LEDの癌関連線維芽細胞および大腸癌に対する効果, 第32回日本消化器癌発生学会総会, Nov. 2021.
136.	Yuuma Wada, Masaaki Nishi, Mitsuo Shimada, Shoko Yamashita, Kouzou Yoshikawa, Takuya Tokunaga, Toshihiro Nakao, Hideya Kashihara, Chie Takasu, Toshiaki Yoshimoto and IWAKAWA Yosuke : 直腸癌の放射線化学療法における肥満細胞の役割, 第32回日本消化器癌発生学会総会, Nov. 2021.
137.	Masaaki Nishi, Mitsuo Shimada, 陳述海, Kouzou Yoshikawa, Takuya Tokunaga, Toshihiro Nakao, Hideya Kashihara, Chie Takasu, Yuuma Wada, Toshiaki Yoshimoto, Shoko Yamashita and IWAKAWA Yosuke : EGCGがCAFの糖代謝を標的とし，腫瘍悪性度を抑制する, 第32回日本消化器癌発生学会総会, Nov. 2021.
138.	Takuya Tokunaga, 杉本真樹, Yu Saitou, Kouzou Yoshikawa, Toshihiro Nakao, Masaaki Nishi, Hideya Kashihara, Chie Takasu, Yuuma Wada, Toshiaki Yoshimoto, Shoko Yamashita, IWAKAWA Yosuke and Mitsuo Shimada : 直腸癌に対する経肛門的アプローチにおけるホログラムと尿道造影を併用した術中ナビゲーション, 第30回日本コンピュータ外科学会大会, Nov. 2021.
139.	Masaaki Nishi, Mitsuo Shimada, Kouzou Yoshikawa, Chie Takasu, Yuuma Wada, Takuya Tokunaga, Toshihiro Nakao, Hideya Kashihara, Toshiaki Yoshimoto, Shoko Yamashita and IWAKAWA Yosuke : ロボット支援胃切除の有用性-Robotic Versus Laparoscopic Gastrectomy: Propensi ty-Matched Analysis.-, 第116回日本消化器病学会四国支部例会, Nov. 2021.
140.	Toshihiro Nakao, Mitsuo Shimada, Kouzou Yoshikawa, Takuya Tokunaga, Masaaki Nishi, Hideya Kashihara, Chie Takasu, Yuuma Wada, Toshiaki Yoshimoto, Shoko Yamashita and IWAKAWA Yosuke : taTMEの手術手技と治療成績, 第116回日本消化器病学会四国支部例会, Nov. 2021.
141.	IWAKAWA Yosuke, Masaaki Nishi, Mitsuo Shimada, Kouzou Yoshikawa, Toshihiro Nakao, Takuya Tokunaga, Chie Takasu, Hideya Kashihara, Yuuma Wada, Toshiaki Yoshimoto and Shoko Yamashita : 胃原発の未分化型多形肉腫の1例, 第83回日本臨床外科学会総会, Nov. 2021.
142.	Shoko Yamashita, Masaaki Nishi, Toshiaki Yoshimoto, Yuuma Wada, Hideya Kashihara, Chie Takasu, Toshihiro Nakao, Takuya Tokunaga, Kouzou Yoshikawa, Koichi Tsuneyama and Mitsuo Shimada : Osteoclast-like giant cellを伴うhamartomatous inverted polypから発生したリンパ球浸潤胃癌の一例, 第83回日本臨床外科学会総会, Nov. 2021.
143.	Shohei Okikawa, Hideya Kashihara, Mitsuo Shimada, Kouzou Yoshikawa, Takuya Tokunaga, Toshihiro Nakao, Masaaki Nishi, Chie Takasu, Yuuma Wada, Toshiaki Yoshimoto, Shoko Yamashita, IWAKAWA Yosuke and Yuji Morine : Duodenal-jejunal bypassの術後早期血糖抑制効果に関する検討, 第83回日本臨床外科学会総会, Nov. 2021.
144.	Toshiaki Yoshimoto, Kouzou Yoshikawa, Takuya Tokunaga, Toshihiro Nakao, Masaaki Nishi, Hideya Kashihara, Chie Takasu, Yuuma Wada, Shoko Yamashita, IWAKAWA Yosuke and Mitsuo Shimada : 大腸癌予後因子としてのFrailの意義, 第83回日本臨床外科学会総会, Nov. 2021.
145.	Masaaki Nishi, Mitsuo Shimada, Kouzou Yoshikawa, Takuya Tokunaga, Toshihiro Nakao, Hideya Kashihara, Chie Takasu, Yuuma Wada, Toshiaki Yoshimoto, Shoko Yamashita and IWAKAWA Yosuke : ロボット支援胃癌手術の標準化, 第83回日本臨床外科学会総会, Nov. 2021.
146.	Takuya Tokunaga, Mitsuo Shimada, Kouzou Yoshikawa, Toshihiro Nakao, Masaaki Nishi, Hideya Kashihara, Chie Takasu, Yuuma Wada, Toshiaki Yoshimoto, Shoko Yamashita and IWAKAWA Yosuke : 直腸切断術に対するTransperineal approachの有用性, 第83回日本臨床外科学会総会, Nov. 2021.
147.	Yuuma Wada, Mitsuo Shimada, Hideya Kashihara, Kouzou Yoshikawa, Takuya Tokunaga, Toshihiro Nakao, Masaaki Nishi, Chie Takasu, Toshiaki Yoshimoto, Shoko Yamashita and IWAKAWA Yosuke : 腹腔鏡下胃癌手術における術前減量プログラムの有用性, 第83回日本臨床外科学会総会, Nov. 2021.
148.	Hideya Kashihara, Mitsuo Shimada, Kouzou Yoshikawa, Takuya Tokunaga, Toshihiro Nakao, Masaaki Nishi, Chie Takasu and Toshiaki Yoshimoto : 経肛門的内視鏡下直腸間膜切除術TaTME併用による安全なロボット支援下直腸切除術の導入, 第83回日本臨床外科学会総会, Nov. 2021.
149.	Toshihiro Nakao, Mitsuo Shimada, Kouzou Yoshikawa, Takuya Tokunaga, Masaaki Nishi, Hideya Kashihara, Chie Takasu, Toshiaki Yoshimoto, Shoko Yamashita and IWAKAWA Yosuke : 横行結腸癌における中結腸動脈の分岐からみた腹腔鏡下手術手技，治療成績, 第83回日本臨床外科学会総会, Nov. 2021.
150.	Kouzou Yoshikawa, Mitsuo Shimada, Takuya Tokunaga, Toshihiro Nakao, Masaaki Nishi, Hideya Kashihara, Chie Takasu, Yuuma Wada, Toshiaki Yoshimoto and Shoko Yamashita : 腹腔鏡下胃全摘OrVil法におけるピットフォールとトラブルシューティング, 第83回日本臨床外科学会総会, Nov. 2021.
151.	Chie Takasu, Mitsuo Shimada, Takuya Tokunaga, Toshihiro Nakao, Hideya Kashihara, Yuuma Wada, Toshiaki Yoshimoto, Shoko Yamashita and NAKASU Chiharu : 地方だからこそ発信できるインクルージョンを目指した働き方改革, 第83回日本臨床外科学会総会, Nov. 2021.
152.	Kouzou Yoshikawa, Mitsuo Shimada, Jun Higashijima, Takuya Tokunaga, Toshihiro Nakao, Masaaki Nishi, Hideya Kashihara, Chie Takasu, Yuuma Wada, Shohei Eto and Toshiaki Yoshimoto : ロボット時代の正確な腹膜播種診断に向けての胃癌Staging laparoscopyの有用性, JDDW 2021, Nov. 2021.
153.	Yuuma Wada, Masaaki Nishi, Mitsuo Shimada, Kouzou Yoshikawa, Takuya Tokunaga, Toshihiro Nakao, Chie Takasu, Hideya Kashihara, Toshiaki Yoshimoto and Shoko Yamashita : 外科手術におけるFrailtyの重要性, 第51回胃外科・術後障害研究会, Nov. 2021.
154.	Toshiaki Yoshimoto, Kouzou Yoshikawa, Toshihiro Nakao, Takuya Tokunaga, Masaaki Nishi, Hideya Kashihara, Chie Takasu, Yuuma Wada, IWAKAWA Yosuke and Mitsuo Shimada : DST吻合における吻合部血流不全のリスク因子:追加切除例の検討, 第59回日本癌治療学会学術集会, Oct. 2021.
155.	Masaaki Nishi, Mitsuo Shimada, Kouzou Yoshikawa, Takuya Tokunaga, Toshihiro Nakao, Hideya Kashihara, Chie Takasu, Yuuma Wada, Toshiaki Yoshimoto and Shoko Yamashita : 高齢者胃癌患者における外科手術の意義-Frailtyの重要性-, 第59回日本癌治療学会学術集会, Oct. 2021.
156.	Takuya Tokunaga, Mitsuo Shimada, Kouzou Yoshikawa, Toshihiro Nakao, Masaaki Nishi, Hideya Kashihara, Chie Takasu, Yuuma Wada, Toshiaki Yoshimoto, Shoko Yamashita and IWAKAWA Yosuke : 当科におけるTaTME手術手技と治療成績, 第59回日本癌治療学会学術集会, Oct. 2021.
157.	Hideya Kashihara, Mitsuo Shimada, Kouzou Yoshikawa, Takuya Tokunaga, Toshihiro Nakao, Masaaki Nishi, Chie Takasu, Yuuma Wada and Toshiaki Yoshimoto : 腹腔鏡下胃・大腸癌手術における多職種介入術前減量プログラムの有用性, 第59回日本癌治療学会学術集会, Oct. 2021.
158.	Kouzou Yoshikawa, Mitsuo Shimada, Toshihiro Nakao, Takuya Tokunaga, Masaaki Nishi, Hideya Kashihara, Chie Takasu, Yuuma Wada and Toshiaki Yoshimoto : 進行胃癌に対するロボット手術の有用性, 第59回日本癌治療学会学術集会, Oct. 2021.
159.	Yuuma Wada, Mitsuo Shimada, Hideya Kashihara, Kouzou Yoshikawa, Toshihiro Nakao, Takuya Tokunaga, Masaaki Nishi, Chie Takasu, Toshiaki Yoshimoto, Shoko Yamashita, IWAKAWA Yosuke and Yasuhiro Hamada : 肥満外科手術における術前NLRの有用性, 第27回外科侵襲とサイトカイン研究会, Oct. 2021.
160.	Masaaki Nishi, Mitsuo Shimada, 陳述海, Kouzou Yoshikawa, Takuya Tokunaga, Toshihiro Nakao, Hideya Kashihara, Chie Takasu, Yuuma Wada, Toshiaki Yoshimoto, Shoko Yamashita and IWAKAWA Yosuke : 癌関連線維芽細胞の糖代謝を標的とした治療法の開発, 第263回徳島医学会学術集会(令和3年度夏期), Aug. 2021.
161.	Toshihiro Nakao, 岩永将輝, 吉田金広, Yukikiyo Kawakami, Satoru Imura and Mitsuo Shimada : 穿孔性虫垂炎術後に十二指腸潰瘍が肝嚢胞へ穿通した1例, 第76回日本消化器外科学会総会, Jul. 2021.
162.	Toshiaki Yoshimoto, Mitsuo Shimada, Kouzou Yoshikawa, Takuya Tokunaga, Toshihiro Nakao, Masaaki Nishi, Hideya Kashihara, Chie Takasu, Yuuma Wada, Shohei Okikawa, Shoko Yamashita, IWAKAWA Yosuke and NAKASU Chiharu : 青色LEDの癌関連線維芽細胞および大腸癌細胞に対する効果, 第115回日本消化器病学会四国支部例会, Jun. 2021.
163.	Kouzou Yoshikawa, Mitsuo Shimada, Takuya Tokunaga, Toshihiro Nakao, Masaaki Nishi, Hideya Kashihara, Chie Takasu and Toshiaki Yoshimoto : 腹腔鏡下胃・大腸癌手術における術前減量プログラムは短期成績改善に寄与する, 第12回日本臨床栄養代謝学会首都圏支部会学術集会, May 2021.
164.	Shohei Eto, Kouzou Yoshikawa, Toshiaki Yoshimoto, Chie Takasu, Hideya Kashihara, Masaaki Nishi, Toshihiro Nakao, Takuya Tokunaga, Jun Higashijima, Takashi Iwata and Mitsuo Shimada : ロボット支援腹腔鏡下前立腺切除術後の鼠径ヘルニア症例に対する治療戦略, 第121回日本外科学会定期学術集会, Apr. 2021.
165.	Shohei Eto, Masaaki Nishi, Toshiaki Yoshimoto, Chie Takasu, Hideya Kashihara, Takuya Tokunaga, Toshihiro Nakao, Jun Higashijima, Kouzou Yoshikawa and Mitsuo Shimada : 下部進行直腸癌におけるCRT後のリンパ球CRP比(LCR)は予後不良因子となる, 第31回日本消化器癌発生学会総会, Nov. 2020.
166.	Yukikiyo Kawakami, 岩永将輝, Toshihiro Nakao, Satoru Imura, 吉田金広 and 住友正幸 : 当院における高齢気胸患者に対する治療の現状, 第73回日本胸部外科学会定期学術集会(Web開催), Oct. 2020.
167.	Yukikiyo Kawakami, Toshihiro Nakao, Satoru Imura, 吉田金広 and 住友正幸 : 過疎地域における呼吸器外科医の役割-気胸患者に対する治療から-, 第37回日本呼吸器外科学会学術集会(Web開催), Sep. 2020.
168.	Toshihiro Nakao, Satoru Imura, Yukikiyo Kawakami, 住友正幸, 吉田金広 and Mitsuo Shimada : Von Recklinghausen病に合併した腫瘍破裂による腹腔内出血を来した小腸多発GISTの1例, 第260回徳島医学会学術集会, Feb. 2020.
169.	Yukikiyo Kawakami, Toshihiro Nakao, Satoru Imura, 吉田金広 and 住友正幸 : 当院で治療された急性膿胸についての臨床的検討, 第72回日本胸部外科学会定期学術集会, Oct. 2019.
170.	Takashi Iwata, Mitsuo Shimada, Kouzou Yoshikawa, Jun Higashijima, Toshihiro Nakao, Masaaki Nishi, Chie Takasu and Masashi Akaike : 若手外科医育成のための卒然教育からの工夫∼移植シンポの早期体験と反転授業を応用した実習の試み∼., 第71回日本消化器外科学会総会, Jul. 2016.
171.	Hideya Kashihara, Mitsuo Shimada, Kouzou Yoshikawa, Jun Higashijima, Toshihiro Nakao, Masaaki Nishi and Chie Takasu : A possible effect of metabolic surgery on diabetes and NASH., 第71回日本消化器外科学会総会, Jul. 2016.
172.	Kouzou Yoshikawa, Mitsuo Shimada, Jun Higashijima, Toshihiro Nakao, Yuji Morine, Masaaki Nishi, Hideya Kashihara, Chie Takasu, Toshiaki Yoshimoto and Hiroki Teraoku : 青色LED光は癌細胞増殖を抑制する., 第71回日本消化器外科学会総会, Jul. 2016.
173.	Kouzou Yoshikawa, Mitsuo Shimada, Jun Higashijima, Toshihiro Nakao, Masaaki Nishi, Hideya Kashihara, Chie Takasu and Daichi Ishikawa : 腹腔鏡下胃全摘の再建におけるトラブルシューティング-Overlap法とOrVil法を経験して-., 第41回日本外科系連合学会学術集会, Jun. 2016.
174.	Kouzou Yoshikawa, Mitsuo Shimada, Toshihiro Nakao, Jun Higashijima, Masaaki Nishi, Hideya Kashihara, Chie Takasu, Masato Yoshikawa, Hiroki Teraoku, Toshiaki Yoshimoto and Atsushi Takata : 直腸癌術前CRT症例におけるKi-67, Survivin発現の意義, 第102回日本消化器病学会総会, Apr. 2016.
175.	Atsushi Takata, Mitsuo Shimada, Kouzou Yoshikawa, Jun Higashijima, Toshihiro Nakao, Masaaki Nishi, Hideya Kashihara, Masato Yoshikawa, Hiroki Teraoku, Toshiaki Yoshimoto and Chie Takasu : 腸管修復および癌幹細胞におけるSonic hedgehogの役割., 第116回日本外科学会定期学術集会, Apr. 2016.
176.	Toshiaki Yoshimoto, Kouzou Yoshikawa, Jun Higashijima, Toshihiro Nakao, Masaaki Nishi, Hideya Kashihara, Chie Takasu, Takuya Tokunaga, Hiroki Teraoku, Masato Yoshikawa, Atsushi Takata and Mitsuo Shimada : 直腸癌術前CRT症例におけるKi-67，Survivin発現の意義, 第116回日本外科学会定期学術集会, Apr. 2016.
177.	小山啓介, Mitsuo Shimada, Kouzou Yoshikawa, Jun Higashijima, Toshihiro Nakao, Takuya Tokunaga, Masaaki Nishi, Hideya Kashihara and Chie Takasu : スリーブ状胃切除におけるGlucagon-like peptide-1の増加は耐糖能異常・脂肪肝の改善に寄与する., 第116回日本外科学会定期学術集会, Apr. 2016.
178.	布村俊幸, Mitsuo Shimada, Kouzou Yoshikawa, Jun Higashijima, Toshihiro Nakao, Masaaki Nishi, Chie Takasu, Hideya Kashihara, Hiroki Teraoku, Masato Yoshikawa and Toshiaki Yoshimoto : 切除不能転移性肝癌を有する透析患者にFOLFOXIRI+Bevを施行しconversionが得られる1例., 第116回日本外科学会定期学術集会, Apr. 2016.
179.	Chie Takasu, Mitsuo Shimada, Kouzou Yoshikawa, Jun Higashijima, Toshihiro Nakao, Takuya Tokunaga, Masaaki Nishi and Hideya Kashihara : IDOによる免疫能と大腸癌肝転移機構., 第116回日本外科学会定期学術集会, Apr. 2016.
180.	Hideya Kashihara, Mitsuo Shimada, Kouzou Yoshikawa, Jun Higashijima, Toshihiro Nakao, Takuya Tokunaga, Masaaki Nishi and Chie Takasu : Roux en Y再建は術後早期より耐糖能異常を改善する., 第116回日本外科学会定期学術集会, Apr. 2016.
181.	Masaaki Nishi, Mitsuo Shimada, Kouzou Yoshikawa, Jun Higashijima, Toshihiro Nakao, Takuya Tokunaga, Hideya Kashihara, Chie Takasu, Hiroki Teraoku, Masato Yoshikawa and Toshiaki Yoshimoto : 膵癌細胞におけるResveratrolのShh pathwayを介した細胞増殖抑制効果, 第116回日本外科学会定期学術集会, Apr. 2016.
182.	Toshihiro Nakao, Mitsuo Shimada, Kouzou Yoshikawa, Jun Higashijima, Takuya Tokunaga, Masaaki Nishi, Hideya Kashihara, Chie Takasu, Hiroki Teraoku, Masato Yoshikawa, Toshiaki Yoshimoto and Atsushi Takata : 進行大腸癌に対する新たな予後予測因子の検討., 第116回日本外科学会定期学術集会, Apr. 2016.
183.	Jun Higashijima, Takashi Iwata, Kouzou Yoshikawa, Toshihiro Nakao, Masaaki Nishi, Hideya Kashihara, Chie Takasu, Hiroki Teraoku, Atsushi Takata and Toshiaki Yoshimoto : 側方転移を有する下部直腸癌への新たな治療戦略., 第116回日本外科学会定期学術集会, Apr. 2016.
184.	Kouzou Yoshikawa, Mitsuo Shimada, Jun Higashijima, Toshihiro Nakao, Masaaki Nishi, Hideya Kashihara, Chie Takasu, Hiroki Teraoku, Toshiaki Yoshimoto, Atsushi Takata and Masato Yoshikawa : 青色LED光は癌細胞増殖を抑制する., 第116回日本外科学会定期学術集会, Apr. 2016.
185.	Masaaki Nishi, Mitsuo Shimada, Kouzou Yoshikawa, Jun Higashijima, Toshihiro Nakao, Hideya Kashihara, Chie Takasu and Takuya Tokunaga : 胃癌におけるPD-1/PD-L1発現の意義., 第49回制癌剤適応研究会, Mar. 2016.
186.	Masaaki Nishi, Mitsuo Shimada, Kouzou Yoshikawa, Hideya Kashihara, Jun Higashijima, Toshihiro Nakao and Chie Takasu : 胃癌における免疫，栄養パラメーターからみた予後予測, 第88回日本胃癌学会総会, Mar. 2016.
187.	Kouzou Yoshikawa, Mitsuo Shimada, Jun Higashijima, Toshihiro Nakao, Masaaki Nishi, Hideya Kashihara, Chie Takasu, Masato Yoshikawa, Hiroki Teraoku, Toshiaki Yoshimoto and Atsushi Takata : 高齢者胃癌症例に対するリンパ節郭清範囲縮小の予後に及ぼす影響, 第88回日本胃癌学会総会, Mar. 2016.
188.	Hideya Kashihara, Kouzou Yoshikawa, Jun Higashijima, Toshihiro Nakao, Takuya Tokunaga, Masaaki Nishi and Chie Takasu : 手技の定型化による腹腔鏡下鼠径ヘルニア修復術の標準化への試み, 第30回四国内視鏡外科研究会, Feb. 2016.
189.	Masaaki Nishi, Mitsuo Shimada, Kouzou Yoshikawa, Jun Higashijima, Toshihiro Nakao, Hideya Kashihara and Chie Takasu : 腹腔鏡下腹壁瘢痕ヘルニア根治術におけるHybrid法の安全性と有用性, 第30回四国内視鏡外科研究会, Feb. 2016.
190.	Jun Higashijima, Mitsuo Shimada, Kouzou Yoshikawa, Toshihiro Nakao, Masaaki Nishi, Hideya Kashihara and Chie Takasu : 縫合不全回避のための大腸癌手術における術中血流評価の有用性, 第30回四国内視鏡外科研究会, Feb. 2016.
191.	Kouzou Yoshikawa, Mitsuo Shimada, Jun Higashijima, Toshihiro Nakao, Takuya Tokunaga, Masaaki Nishi, Hideya Kashihara and Chie Takasu : 腹腔鏡補助下胃全摘術の食道空腸吻合法におけるOrvil法の有用性と再建の工夫, 第30回四国内視鏡外科研究会, Feb. 2016.
192.	Masaaki Nishi, Mitsuo Shimada, Kouzou Yoshikawa, Jun Higashijima, Toshihiro Nakao, Takuya Tokunaga, Hideya Kashihara and Chie Takasu : 胃癌におけるPD1/PDL1発現の意義, 第252回徳島医学会学術集会, Feb. 2016.
193.	良元俊昭, Kouzou Yoshikawa, Jun Higashijima, Toshihiro Nakao, Masaaki Nishi, Hideya Kashihara, Chie Takasu and Mitsuo Shimada : 腹腔鏡下直腸切断術後に麻痺性イレウス・ARDS・AKIを来たし集学的治療により救命しえた一例, 第24回徳島外科術後管理研究会, Feb. 2016.
194.	Toshihiro Nakao, Mitsuo Shimada, Kouzou Yoshikawa, Jun Higashijima, Takuya Tokunaga, Masaaki Nishi, Chie Takasu and Hideya Kashihara : 進行大腸癌におけるFbxw7発現は再発予後規定因子となりうる, 第84回大腸癌研究会, Jan. 2016.
195.	Masaaki Nishi, Mitsuo Shimada, Kouzou Yoshikawa, Jun Higashijima, Toshihiro Nakao, Takuya Tokunaga, Hideya Kashihara and Chie Takasu : 胃癌におけるPD-1/PD-L1発現の意義, 第22回外科侵襲とサイトカイン研究会, Dec. 2015.
196.	Hideya Kashihara, Mitsuo Shimada, Kouzou Yoshikawa, Jun Higashijima, Toshihiro Nakao, Takuya Tokunaga, Masaaki Nishi and Chie Takasu : 手技の定型化により腹腔鏡下鼠径ヘルニア手術の標準化は可能である, 第28回日本内視鏡外科学会総会, Dec. 2015.
197.	Toshihiro Nakao, Mitsuo Shimada, Kouzou Yoshikawa, Jun Higashijima, Takuya Tokunaga, Masaaki Nishi, Hideya Kashihara and Chie Takasu : 進行大腸癌に対する腹腔鏡手術vs開腹手術のpropensity scoreによる検討, 第28回日本内視鏡外科学会総会, Dec. 2015.
198.	Jun Higashijima, Hideya Kashihara, Masaaki Nishi, Toshihiro Nakao, Chie Takasu, Kouzou Yoshikawa, Takashi Iwata and Mitsuo Shimada : 縫合不全回避のための大腸癌手術における術中血流評価の有用性, 第28回日本内視鏡外科学会総会, Dec. 2015.
199.	Kouzou Yoshikawa, Mitsuo Shimada, Jun Higashijima, Toshihiro Nakao, Masaaki Nishi, Hideya Kashihara, Chie Takasu and Takuya Tokunaga : 腹腔鏡補助下胃全摘術の食道空腸吻合法におけるOrVil法の有用性と再建の工夫, 第28回日本内視鏡外科学会総会, Dec. 2015.
200.	Takashi Iwata, Mitsuo Shimada, Kouzou Yoshikawa, Jun Higashijima, Toshihiro Nakao, Masaaki Nishi, Takuya Tokunaga, Chie Takasu and Hideya Kashihara : 手術シミュレーションを利用した鏡視下手技が苦手な学生の同定とトレーニングの工夫, 第28回日本内視鏡外科学会総会, Dec. 2015.
201.	Kouzou Yoshikawa, Mitsuo Shimada, Jun Higashijima, Toshihiro Nakao, Masaaki Nishi, Hideya Kashihara and Chie Takasu : 腹腔鏡下腹壁瘢痕ヘルニア根治術におけるHybrid法の安全性と有用性, 第77回日本臨床外科学会総会, Nov. 2015.
202.	Toshihiro Nakao, Mitsuo Shimada, Kouzou Yoshikawa, Jun Higashijima, Takuya Tokunaga, Masaaki Nishi, Hideya Kashihara and Chie Takasu : Glasgow prognostic score(GPS)を用いた腹腔鏡下進行大腸癌手術における予後予測の検討, 第77回日本臨床外科学会総会, Nov. 2015.
203.	Jun Higashijima, Hideya Kashihara, Chie Takasu, Masaaki Nishi, Toshihiro Nakao, Kouzou Yoshikawa, Takashi Iwata and Mitsuo Shimada : 下部直腸癌に対する術前化学放射線療法による合併症の予後への影響, 第77回日本臨床外科学会総会, Nov. 2015.
204.	Masaaki Nishi, Mitsuo Shimada, Jun Higashijima, Kouzou Yoshikawa, Toshihiro Nakao, Takuya Tokunaga, Hideya Kashihara and Chie Takasu : 直腸癌手術における縫合不全回避のための術中血流評価の有用性, 第24回日本コンピュータ外科学会大会, Nov. 2015.
205.	Hideya Kashihara, Mitsuo Shimada, Kouzou Yoshikawa, Jun Higashijima, Toshihiro Nakao, Takuya Tokunaga, Masaaki Nishi and Chie Takasu : 非癌部Thrombospondin-1(THBS1)発現は胃発癌に関連する, 第26回日本消化器癌発生学会総会, Nov. 2015.
206.	Kouzou Yoshikawa, Mitsuo Shimada, Jun Higashijima, Toshihiro Nakao, Masaaki Nishi, Hideya Kashihara and Chie Takasu : LED光照射による癌幹細胞制御に関する研究, 第26回日本消化器癌発生学会総会, Nov. 2015.
207.	Hideya Kashihara, Mitsuo Shimada, Kouzou Yoshikawa, Jun Higashijima, Toshihiro Nakao, Takuya Tokunaga, Masaaki Nishi and Chie Takasu : 肥満患者に対するスリーブ状胃切除術の有用性に関する検討, 日本消化器病学会四国支部第104回例会, Nov. 2015.
208.	Jun Higashijima, Toshihiro Nakao, Masaaki Nishi, Hideya Kashihara, Chie Takasu, Takuya Tokunaga, 良元俊昭, 髙田厚史 and Mitsuo Shimada : 直腸癌術前CRT症例におけるKi-67発現の意義, 第53回日本癌治療学会学術集会, Oct. 2015.
209.	Hideya Kashihara, Mitsuo Shimada, Takashi Iwata, Kouzou Yoshikawa, Jun Higashijima, Toshihiro Nakao, Takuya Tokunaga, Masaaki Nishi and Chie Takasu : TGFβを介した腫瘍免疫機構は治癒切除した胃癌再発に関与する, 第53回日本癌治療学会学術集会, Oct. 2015.
210.	Toshihiro Nakao, Mitsuo Shimada, Kouzou Yoshikawa, Jun Higashijima, Takuya Tokunaga, Masaaki Nishi, Hideya Kashihara and Chie Takasu : StageII/III大腸癌における腹腔鏡手術vs開腹手術のpropensity scoreによる検討, 第53回日本癌治療学会学術集会, Oct. 2015.
211.	Jun Higashijima, Takashi Iwata, Kouzou Yoshikawa, Toshihiro Nakao, Masaaki Nishi, Hideya Kashihara, Chie Takasu and Mitsuo Shimada : 大腸癌肝転移症例における肝転移巣のKISS1発現に関する検討, 第53回日本癌治療学会学術集会, Oct. 2015.
212.	Masaaki Nishi, Mitsuo Shimada, Kouzou Yoshikawa, Jun Higashijima, Toshihiro Nakao, Takuya Tokunaga, Hideya Kashihara, Chie Takasu and 江藤祥平 : 胃癌におけるPD-1発現の意義, 第74回日本癌学会学術総会, Oct. 2015.
213.	Toshihiro Nakao, Mitsuo Shimada, Kouzou Yoshikawa, Jun Higashijima, Takuya Tokunaga, Masaaki Nishi, Hideya Kashihara, Chie Takasu and 江藤祥平 : StageII/III大腸癌腹腔鏡手術と開腹手術のpropensity scoreによる検討, JDDW 2015, Oct. 2015.
214.	江藤祥平, Mitsuo Shimada, Takashi Iwata, Kouzou Yoshikawa, Jun Higashijima, Toshihiro Nakao, Masaaki Nishi and Chie Takasu : 進行胃癌におけるPD-1/PD-L1発現は相関し，予後と関連する, 第70回日本消化器外科学会総会, Jul. 2015.
215.	Toshihiro Nakao, Mitsuo Shimada, Takashi Iwata, Kouzou Yoshikawa, Jun Higashijima, Masaaki Nishi, Chie Takasu and 江藤祥平 : Stage Ⅱ/Ⅲ大腸癌に対する腹腔鏡と開腹手術のプロペンシティスコアによる検, 第70回日本消化器外科学会総会, Jul. 2015.
216.	Masaaki Nishi, Mitsuo Shimada, Kouzou Yoshikawa, Jun Higashijima, Takuya Tokunaga, Toshihiro Nakao, Chie Takasu and 江藤祥平 : 腹腔鏡下胃切除における3Dシミュレーションとナビゲーション, 第70回日本消化器外科学会総会, Jul. 2015.
217.	Jun Higashijima, Mitsuo Shimada, Takashi Iwata, Kouzou Yoshikawa, Toshihiro Nakao, Masaaki Nishi, Chie Takasu and 江藤祥平 : 局所進行下部直腸癌に対する術前化学放射線療法の奏効率向上を目指して, 第70回日本消化器外科学会総会, Jul. 2015.
218.	Kouzou Yoshikawa, Mitsuo Shimada, Jun Higashijima, Toshihiro Nakao, Masaaki Nishi, Chie Takasu, Hideya Kashihara and 江藤祥平 : 合併症から学ぶ腹腔鏡下胃全摘出術R-Y再建の工夫-視野展開と吻合の工夫-, 第70回日本消化器外科学会総会, Jul. 2015.
219.	Takashi Iwata, Mitsuo Shimada, Kouzou Yoshikawa, Jun Higashijima, Toshihiro Nakao, Masaaki Nishi, Takuya Tokunaga, Chie Takasu, 江藤祥平 and Masashi Akaike : 内視鏡手術時代における卒前教育からのoff-the-jobと反転授業を応用した実習の試み, 第70回日本消化器外科学会総会, Jul. 2015.
220.	Jun Higashijima, Mitsuo Shimada, Takashi Iwata, Kouzou Yoshikawa, Toshihiro Nakao, Takuya Tokunaga, Masaaki Nishi and Chie Takasu : 切除可能大腸癌肝転移に対する原発・転移巣同時切除の妥当性, 第83回大腸癌研究会, Jul. 2015.
221.	Masaaki Nishi, Mitsuo Shimada, Kouzou Yoshikawa, Jun Higashijima, Toshihiro Nakao, Takuya Tokunaga, Hideya Kashihara, Chie Takasu and 江藤祥平 : LED光照射による癌幹細胞制御に関する研究, 第24 回日本癌病態治療研究会, Jun. 2015.
222.	Jun Higashijima, Mitsuo Shimada, Takashi Iwata, Kouzou Yoshikawa, Toshihiro Nakao, Masaaki Nishi, Hideya Kashihara, Chie Takasu and 江藤祥平 : 大腸癌手術における縫合不全回避のための工夫:ICG蛍光システムを用いた腸管血流評価の有用性について, 第103回例会日本消化器病学会総会四国支部, Jun. 2015.
223.	Toshihiro Nakao, Mitsuo Shimada, Takashi Iwata, Kouzou Yoshikawa, Jun Higashijima, Takuya Tokunaga, Masaaki Nishi, Hideya Kashihara, Chie Takasu and 江藤祥平 : 腹腔鏡下大腸癌手術におけるICG蛍光法の有用性, 第69回手術手技研究会, May 2015.
224.	Kouzou Yoshikawa, Mitsuo Shimada, Jun Higashijima, Toshihiro Nakao, Masaaki Nishi, Hideya Kashihara and Chie Takasu : 腹腔鏡下胃全摘出術R-Y再建の工夫―視野展開と吻合の工夫―, 第69回手術手技研究会, May 2015.
225.	Toshihiro Nakao, Mitsuo Shimada and Kouzou Yoshikawa : がん幹細胞制御におけるSonic Hedgehog signalingの役割, 第101回日本消化器病学会総会, Apr. 2015.
226.	Kouzou Yoshikawa, Toshihiro Nakao and Chie Takasu : 地方における胃癌に対するロボット手術の現状, 第101回日本消化器病学会総会, Apr. 2015.
227.	良元俊昭, Mitsuo Shimada, Takashi Iwata, Kouzou Yoshikawa, Jun Higashijima, Toshihiro Nakao, Masaaki Nishi, Chie Takasu and 江藤祥平 : 直腸癌に対する腹腔鏡下直腸切断術後骨盤死腔炎に関する検討, 第115回日本外科学会定期学術集会, Apr. 2015.
228.	江藤祥平, Mitsuo Shimada, Takashi Iwata, Kouzou Yoshikawa, Jun Higashijima, Takuya Tokunaga, Toshihiro Nakao, Masaaki Nishi and Chie Takasu : 胃癌におけるPD-1,THBS1発現は再発と関係する, 第115回日本外科学会定期学術集会, Apr. 2015.
229.	Toshihiro Nakao, Mitsuo Shimada, Takashi Iwata, Kouzou Yoshikawa, Jun Higashijima, Masaaki Nishi, Chie Takasu and 江藤祥平 : 非癌部組織におけるThrombospondin-1(THBS1)と胃発癌との関連, 第115回日本外科学会定期学術集会, Apr. 2015.
230.	Masaaki Nishi, Mitsuo Shimada, Kouzou Yoshikawa, Jun Higashijima, Toshihiro Nakao, Takuya Tokunaga, Chie Takasu, 江藤祥平 and 寺奥大貴 : 膵癌細胞におけるResveratrolの autophagyを介した細胞増殖抑制効果, 第115回日本外科学会定期学術集会, Apr. 2015.
231.	Takashi Iwata, Mitsuo Shimada, Kouzou Yoshikawa, Jun Higashijima, Toshihiro Nakao, Masaaki Nishi, Takuya Tokunaga, Chie Takasu and Masashi Akaike : 鏡視下手技が苦手な学生をどうトレーニングするか?―off-the-job トレーニングの工夫―, 第115回日本外科学会定期学術集会, Apr. 2015.
232.	Jun Higashijima, Mitsuo Shimada, Takashi Iwata, Kouzou Yoshikawa, Toshihiro Nakao, Masaaki Nishi, Chie Takasu and 江藤祥平 : 局所進行直腸癌に対する集学的治療戦略/下部直腸癌に対する術前化学放射線療法の合併症が予後に与える影響に関する検討, 第115回日本外科学会定期学術集会, Apr. 2015.
233.	Masaaki Nishi, Mitsuo Shimada, Kouzou Yoshikawa, Jun Higashijima, Toshihiro Nakao, Chie Takasu, 江藤祥平, 寺奥大貴, Takashi Iwata, 和田大助, 坂東儀昭, 尾形信也, Hideya Kashihara, Nobuhiro Kurita and Takuya Tokunaga : 術前3Dシュミュレーションを用いた腹腔鏡下胃切除, 第87回日本胃癌学会総会, Mar. 2015.
234.	Kouzou Yoshikawa, Mitsuo Shimada, Nobuhiro Kurita, Takashi Iwata, Jun Higashijima, Toshihiro Nakao, Masaaki Nishi, Hideya Kashihara, Chie Takasu, 坂東儀昭, 尾形信也 and 和田大助 : 腹腔鏡下胃全摘出術後の再建における当科での工夫ーOverlapとOrvilとの比較ー, 第87回日本胃癌学会総会, Mar. 2015.
235.	良元俊昭, Mitsuo Shimada, Takashi Iwata, Kouzou Yoshikawa, Jun Higashijima, Toshihiro Nakao, Masaaki Nishi, Chie Takasu and 江藤祥平 : 化学放射線療後に骨盤内臓全摘術を施行し，骨盤死腔炎から小腸会陰瘻を合併した1例, 第23回徳島外科術後管理研究会, Feb. 2015. (Keyword) 国内学会
236.	Toshihiro Nakao, Mitsuo Shimada, Takashi Iwata, Kouzou Yoshikawa, Jun Higashijima, Masaaki Nishi, Chie Takasu and 江藤祥平 : 腹腔鏡下直腸手術におけるICG蛍光法の検討, 第29回四国内視鏡外科研究会, Feb. 2015. (Keyword) 国内学会
237.	Masaaki Nishi, Mitsuo Shimada, Kouzou Yoshikawa, Jun Higashijima, Toshihiro Nakao, Takuya Tokunaga, Chie Takasu, 江藤祥平 and 寺奥大貴 : 腹腔鏡下胃切除における術前3Dシミュレーションの有用性, 第29回四国内視鏡外科研究会, Feb. 2015. (Keyword) 国内学会
238.	Jun Higashijima, 江藤祥平, Chie Takasu, Masaaki Nishi, Toshihiro Nakao, Kouzou Yoshikawa, Takashi Iwata and Mitsuo Shimada : StageⅡ,Ⅲ結腸癌に対する腹腔鏡下手術の妥当性の検討:開腹手術との比較検討, 第82回大腸癌研究会, Jan. 2015. (Keyword) 国内学会
239.	江藤祥平, Kouzou Yoshikawa, Mitsuo Shimada, Jun Higashijima, Toshihiro Nakao, Masaaki Nishi and Chie Takasu : 腹腔鏡下胃全摘術における肝圧排法による視野展開の有用性, 第76回日本臨床外科学会総会, Nov. 2014. (Keyword) 国内学会
240.	Toshihiro Nakao, Mitsuo Shimada, Takashi Iwata, Kouzou Yoshikawa, Jun Higashijima, Masaaki Nishi, Chie Takasu, 江藤祥平, 寺奥大貴 and 吉川雅登 : 腹腔鏡下胃切除術ERASプロトコルにおける大建中湯(DKT:TJ-100)の有用性に関する検討, 第76回日本臨床外科学会総会, Nov. 2014. (Keyword) 国内学会
241.	Chie Takasu, Masaaki Nishi, Takashi Iwata, Jun Higashijima, Kouzou Yoshikawa, Toshihiro Nakao, Takuya Tokunaga, 江藤祥平 and Mitsuo Shimada : 肥満患者に対するスリーブ状胃切除術の成績, 第76回日本臨床外科学会総会, Nov. 2014. (Keyword) 国内学会
242.	Masaaki Nishi, Mitsuo Shimada, Kouzou Yoshikawa, Jun Higashijima, Takuya Tokunaga, Toshihiro Nakao, Hideya Kashihara, Chie Takasu and 江藤祥平 : 若手外科医のための腹腔鏡下胃切除における術前3Dシミュレーションの有用性, 第76回日本臨床外科学会総会, Nov. 2014. (Keyword) 国内学会
243.	Kouzou Yoshikawa, Mitsuo Shimada, Jun Higashijima, Toshihiro Nakao, Masaaki Nishi, Chie Takasu and 江藤祥平 : 腹腔鏡下胃全摘出術における視野展開と吻合の工夫, 第76回日本臨床外科学会総会, Nov. 2014. (Keyword) 国内学会
244.	江藤祥平, Mitsuo Shimada, Takashi Iwata, Kouzou Yoshikawa, Jun Higashijima, Toshihiro Nakao, Masaaki Nishi and Chie Takasu : 胃癌におけるStathmin1発現とH.pylori 感染の関連, 第25回日本消化器癌発生学会総会, Nov. 2014. (Keyword) 国内学会
245.	Toshihiro Nakao, Mitsuo Shimada, Takashi Iwata, Kouzou Yoshikawa, Jun Higashijima, Masaaki Nishi, Chie Takasu, 江藤祥平, 寺奥大貴 and 吉川雅登 : Sonic Hedgehog signalingの癌幹細胞における意義, 第25回日本消化器癌発生学会総会, Nov. 2014. (Keyword) 国内学会
246.	Masaaki Nishi, Mitsuo Shimada, Kouzou Yoshikawa, Jun Higashijima, Toshihiro Nakao, Chie Takasu and 江藤祥平 : 腹腔鏡下胃切除における術前3Dシミュレーション∼若手教育のために∼, 第23回日本コンピュータ外科学会, Nov. 2014. (Keyword) 国内学会
247.	江藤祥平, Kouzou Yoshikawa, Takashi Iwata, Jun Higashijima, Takuya Tokunaga, Toshihiro Nakao, Masaaki Nishi, Chie Takasu and Mitsuo Shimada : 大腸癌細胞におけるCD47抑制と放射線増感効果の検討, 第102回日本消化器病学会四国支部例会, Nov. 2014. (Keyword) 国内学会
248.	Toshihiro Nakao, 江藤祥平 and Mitsuo Shimada : 胃癌術前栄養評価としてのSarcopenia測定の意義, 第22回日本消化器関連学会週間(JDDW), Oct. 2014. (Keyword) 国内学会
249.	Masaaki Nishi, Mitsuo Shimada, Nobuhiro Kurita, Kouzou Yoshikawa, Jun Higashijima, Toshihiro Nakao, Takuya Tokunaga, Chie Takasu and 江藤祥平 : 胃GISTに対する腹腔鏡・内視鏡合同手術(LECS)の検討, 第22回日本消化器関連学会週間(JDDW), Oct. 2014. (Keyword) 国内学会
250.	Jun Higashijima, 江藤祥平, Chie Takasu, Masaaki Nishi, Toshihiro Nakao, Kouzou Yoshikawa, Takashi Iwata and Mitsuo Shimada : StageⅡ,Ⅲ結腸癌に対する腹腔鏡下手術の妥当性についての検討, 第27回日本内視鏡外科学会総会, Oct. 2014. (Keyword) 国内学会
251.	Masaaki Nishi, Mitsuo Shimada, Kouzou Yoshikawa, Jun Higashijima, Takuya Tokunaga, Toshihiro Nakao, Chie Takasu and 江藤祥平 : 腹腔鏡下胃切除における術前3Dシュミュレーションの有用性, 第27回日本内視鏡外科学会総会, Oct. 2014. (Keyword) 国内学会
252.	Chie Takasu, Jun Higashijima, Takashi Iwata, Kouzou Yoshikawa, Toshihiro Nakao, Masaaki Nishi, 江藤祥平, 寺奥大貴, 吉川雅登 and Mitsuo Shimada : 直腸切除術における縫合不全回避のための工夫:ICG蛍光法を用いた腸管血流評価, 第27回日本内視鏡外科学会総会, Oct. 2014. (Keyword) 国内学会
253.	Kouzou Yoshikawa, Mitsuo Shimada, Takashi Iwata, Jun Higashijima, Toshihiro Nakao, Masaaki Nishi, Chie Takasu and 江藤祥平 : 腹腔鏡補助下胃切除術の定型化は技術認定医取得に有用である, 第27回日本内視鏡外科学会総会, Oct. 2014. (Keyword) 国内学会
254.	Takashi Iwata, Mitsuo Shimada, Kouzou Yoshikawa, Jun Higashijima, Masaaki Nishi, Takuya Tokunaga, Chie Takasu, 江藤祥平, Toshihiro Nakao and Masashi Akaike : 内視鏡外科手術におけるOff-the-jobトレーニングを科学する, 第27回日本内視鏡外科学会総会, Oct. 2014. (Keyword) 国内学会
255.	Masaaki Nishi, Mitsuo Shimada, Kouzou Yoshikawa, Jun Higashijima, Toshihiro Nakao, Chie Takasu and 江藤祥平 : LTGにおける食道空腸吻合のPitfallと工夫, 第89回中国四国外科学会総会・(第19回中国四国内視鏡外科研究会), Sep. 2014. (Keyword) 国内学会
256.	Kouzou Yoshikawa, Mitsuo Shimada, Jun Higashijima, Toshihiro Nakao, Chie Takasu and 江藤祥平 : 肥満患者に対するスリーブ状胃切除術の成績, 第89回中国四国外科学会総会・(第19回中国四国内視鏡外科研究会), Sep. 2014. (Keyword) 国内学会
257.	Jun Higashijima, Mitsuo Shimada, Takashi Iwata, Kouzou Yoshikawa, Masaaki Nishi, Toshihiro Nakao, Chie Takasu and 江藤祥平 : 下部直腸癌に対する新たな術前化学放射線療法(SOX+Bev)について, 第52回日本癌治療学会学術集会, Aug. 2014. (Keyword) 国内学会
258.	Kouzou Yoshikawa, Mitsuo Shimada, Nobuhiro Kurita, Takashi Iwata, Jun Higashijima, Motoya Chikakiyo, Toshihiro Nakao, Masaaki Nishi, Hideya Kashihara, Chie Takasu, 松本規子 and 江藤祥平 : 腹腔鏡補助下胃切除術後の再発危険因子, 第52回日本癌治療学会学術集会, Aug. 2014. (Keyword) 国内学会
259.	Jun Higashijima, 江藤祥平, Chie Takasu, Masaaki Nishi, Toshihiro Nakao, Kouzou Yoshikawa, Takashi Iwata and Mitsuo Shimada : 高齢者結腸癌に対する腹腔鏡下手術の妥当性についての検討, 第81回大腸癌研究会, Jul. 2014. (Keyword) 国内学会
260.	Takashi Iwata, Mitsuo Shimada, Nobuhiro Kurita, Horohiko Sato, Kouzou Yoshikawa, Jun Higashijima, Masaaki Nishi, Motoya Chikakiyo, Takuya Tokunaga and Toshihiro Nakao : 卒前・卒後の内視鏡外科手術教育におけるトレーニングの検討, 第39回日本外科系連合学会学術集会, Jun. 2014. (Keyword) 国内学会
261.	Kouzou Yoshikawa, Mitsuo Shimada, Nobuhiro Kurita, Takashi Iwata, Jun Higashijima, Toshihiro Nakao, Masaaki Nishi, Hideya Kashihara, Chie Takasu and 江藤祥平 : 胃癌におけるda Vinci Surgical System(DVSS)導入期における現状, 第39回日本外科系連合学会学術集会, Jun. 2014. (Keyword) 国内学会
262.	Toshihiro Nakao, Mitsuo Shimada, Takashi Iwata, Jun Higashijima, Kouzou Yoshikawa, Masaaki Nishi, Chie Takasu and 江藤祥平 : 局所進行下部直腸癌に対する術前化学放射線療法併用腹腔鏡下手術は標準治療になりうるか?, 第101回日本消化器病学会四国支部例会, Jun. 2014. (Keyword) 国内学会
263.	Kouzou Yoshikawa, Mitsuo Shimada, Nobuhiro Kurita, Takashi Iwata, Jun Higashijima, Toshihiro Nakao, Masaaki Nishi, Chie Takasu, Hideya Kashihara and 江藤祥平 : 腹腔鏡下腹壁瘢痕ヘルニア根治術における安全性と有用性, 第68回手術手技研究会, May 2014. (Keyword) 国内学会
264.	Masaaki Nishi, Mitsuo Shimada, Kouzou Yoshikawa, Jun Higashijima, Toshihiro Nakao, Chie Takasu, 江藤祥平, 寺奥大貴, Takashi Iwata, 和田大助, 坂東儀昭, 尾方信也, Hideya Kashihara, Nobuhiro Kurita and Takuya Tokunaga : 術前3Dシュミュレーションを用いた腹腔鏡下胃切除, 第87回日本胃癌学会総会, Mar. 2014. (Keyword) 国内学会
265.	Kouzou Yoshikawa, Mitsuo Shimada, Nobuhiro Kurita, Takashi Iwata, Jun Higashijima, Toshihiro Nakao, Masaaki Nishi, Hideya Kashihara, Chie Takasu, 坂東儀昭, 尾方信也 and 和田大助 : 腹腔鏡下胃全摘出術後の再建における当科での工夫ーOverlapとOrvilとの比較ー, 第87回日本胃癌学会総会, Mar. 2014. (Keyword) 国内学会

Grants-in-Aid for Scientific Research (KAKEN Grants Database @ NII.ac.jp)

AIを用いた対話型医療面接トレーニングシステムの開発 (Project/Area Number: 22K10363 )
The Impact of the correlation between thrombospondin-1 and immune checkpoint (Project/Area Number: 16K19898 )
Search by Researcher Number (60531754)

Assistant Professor : Nakao, Toshihiro

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Grants-in-Aid for Scientific Research (KAKEN Grants Database @ NII.ac.jp)