Tokushima University / Educator and Researcher Directory --- Ueno, Masaharu

Personal Web Page

https://researchmap.jp/read80361509 (researchmap)

https://orcid.org/0000-0001-5253-0968 (ORCID)

Field of Study

○	Reaction Organic Chemistry, Green Chemistry

Subject of Study

○	グリーンケミストリー, 新規反応手法の開発及び生物活性化合物合成への応用

Book / Paper

Book:

1.	岩澤康裕, 小林修, 冨重圭一, 関根泰, Masaharu Ueno and 唯美津木 : 化学の指針シリーズ触媒化学, Shokabo Publishing Co., Ltd., May 2019.
2.	Masaharu Ueno and 小林修 : フロー・マイクロ合成-基礎から実際の合成・製造まで-, 第20章気液反応, Kagaku-Dojin Publishing Company,INC, Jul. 2014.
3.	Masaharu Ueno and 小林修 : マイクロ・ナノ化学チップと医療・環境・バイオ分析, 第32章マイクロリアクター・合成, 技術教育出版社, Jan. 2009.
4.	Masaharu Ueno and Shu Kobayashi : Enantioselective Synthesis of -Amino Acids.2nd Edition, Chapter 6 Catalytic Enantioselective Mannich Reaction, John Wiley & Sons, Inc., Jan. 2005.
5.	Masaharu Ueno and 北森武彦 : 触媒活用大事典, 第III部展望編「4.マイクロリアクタにおける触媒 catalysis for microreactor」, 工業調査会, Dec. 2004.
6.	Masaharu Ueno : マイクロ化学チップの技術と応用, 5.6 表面修飾, MARUZEN Co.,Ltd., Sep. 2004.
7.	Shu Kobayashi and Masaharu Ueno : Comprehensive Asymmetric Catalysis: Supplement 1., Chapter 29.5 Mannich Reaction, Springer, Sep. 2003.

Academic Paper (Judged Full Paper):

1.	Miho Kobatake, Norikazu Miyoshi and Masaharu Ueno : One-pot Tandem Coupling Method for the Short Step Formal Synthesis of Riccardin C, Chemistry - A European Journal, Vol.29, e202203805, 2023. (Summary) One-pot reactions reduce reagent amounts and circumvent process treatments, such as work-up and purifications in multi-step reactions. In this study, we achieved the formal total synthesis of riccardin C through a one-pot reaction by simultaneously linking four units through two Sonogashira coupling reactions and one Suzuki coupling reaction, followed by reduction and deprotection. Thus, this one-pot method comprised five steps and did not require the purification of intermediate reaction mixtures, which saves resources, such as reagents and solvents, and expedites the work process. (Tokushima University Institutional Repository) ● Metadata: 117971 (Link to Publication Site) ● Publication site (DOI): 10.1002/chem.202203805 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 36573022 ● Search Scopus @ Elsevier (PMID): 36573022 ● Search Scopus @ Elsevier (DOI): 10.1002/chem.202203805 (Tokushima University Institutional Repository: 117971, DOI: 10.1002/chem.202203805, PubMed: 36573022)
2.	Keigo Kumagai, Shota Sakai, Masaharu Ueno, Michiyo Kataoka, Shu Kobayashi and Kentaro Hanada : Chlamydial Infection-Dependent Synthesis of Sphingomyelin as a Novel Anti-Chlamydial Target of Ceramide Mimetic Compounds, International Journal of Molecular Sciences, Vol.23, 14697, 2022. (Tokushima University Institutional Repository) ● Metadata: 118016 (Link to Publication Site) ● Publication site (DOI): 10.3390/ijms232314697 (Link to Search Site for Scientific Articles) ● Search Scopus @ Elsevier (DOI): 10.3390/ijms232314697 (Tokushima University Institutional Repository: 118016, DOI: 10.3390/ijms232314697)
3.	Norikazu Miyoshi, Aki Miyoshi, Yasuaki Miyazaki, Shigeki Kubo and Masaharu Ueno : Practical Method for Hydroxyl-Group Protection Using Strontium Metal and Readily Available Silyl Chlorides, Chemical Communications, Vol.58, No.43, 6312-6315, 2022. (Summary) We have found that the etherification of silyl-protected secondary alcohols proceeds smoothly in the presence of strontium metal using silyl chloride instead of the expensive, yet more reactive, and commonly used silyl triflate. The reaction occurred almost completely with various alcohols. (Keyword) Alcohols / Chlorides / Strontium (Tokushima University Institutional Repository) ● Metadata: 117879 (Link to Publication Site) ● Publication site (DOI): 10.1039/d2cc01105k (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 35522074 ● Search Scopus @ Elsevier (PMID): 35522074 ● Search Scopus @ Elsevier (DOI): 10.1039/d2cc01105k (Tokushima University Institutional Repository: 117879, DOI: 10.1039/d2cc01105k, PubMed: 35522074)
4.	Norikazu Miyoshi, Shohdai Kimura, Shigeki Kubo, Satoshi D. Ohmura and Masaharu Ueno : Chemoselective Ketone Synthesis by the Strontium-mediated Alkylation or Arylation of N,N-Dimethylamides or Urea, Asian Journal of Organic Chemistry, Vol.9, No.10, 1660-1664, 2020. (Tokushima University Institutional Repository) ● Metadata: 116160 (Link to Publication Site) ● Publication site (DOI): 10.1002/ajoc.202000389 (Link to Search Site for Scientific Articles) ● Search Scopus @ Elsevier (DOI): 10.1002/ajoc.202000389 (Tokushima University Institutional Repository: 116160, DOI: 10.1002/ajoc.202000389)
5.	Masaharu Ueno, Norikazu Miyoshi, Hanada Kentaro and Kobayashi Shu : Three-component, one-pot tandem Sonogashira/Suzuki-Miyaura coupling reactions for the synthesis of a library of ceramide-transport protein inhibitors that were designed in silico, Asian Journal of Organic Chemistry, Vol.9, No.2, 267-273, 2020. (Summary) We have developed a onepot, tandem Sonogashira/SuzukiMiyaura coupling reaction, which is unknown synthetically, and applied it for the synthesis of a library of potential natural ligand nonmimetic inhibitors of the lipidtransfer protein, ceramidetransport protein (CERT). The characteristic feature of this reaction is that the twostep coupling reaction proceeds smoothly with only 5 mol% of palladium catalyst. Furthermore, the location of the formed carboncarbon bond would be strictly defined because of the difference in reactivity. Therefore, many derivatives could be synthesized in high yields without the formation of regioisomeric byproducts by the same procedure. We also performed a semigram scale synthesis of several derivatives to provide the bioactive assey. After synthesizing as many as 113 derivatives, we identified a nonnatural mimetic inhibitor with activity comparable to that of the known inhibitor (1R,3S)-HPA-12. (Tokushima University Institutional Repository) ● Metadata: 115072 (Link to Publication Site) ● Publication site (DOI): 10.1002/ajoc.201900689 (Link to Search Site for Scientific Articles) ● Search Scopus @ Elsevier (DOI): 10.1002/ajoc.201900689 (Tokushima University Institutional Repository: 115072, DOI: 10.1002/ajoc.201900689)
6.	Satoshi D. Ohmura, Keisuke Yamana, Masaharu Ueno and Norikazu Miyoshi : Methoxycarbonyl Group as a Conformational Regulator for the Benzene Ring of Triphenylamines, ChemistrySelect, Vol.4, No.13, 3799-3802, 2019. (Keyword) triphenylamine / luminescence / substitutional effect / methoxycarbonyl group (Tokushima University Institutional Repository) ● Metadata: 113987 (Link to Publication Site) ● Publication site (DOI): 10.1002/slct.201900076 (Link to Search Site for Scientific Articles) ● Search Scopus @ Elsevier (DOI): 10.1002/slct.201900076 (Tokushima University Institutional Repository: 113987, DOI: 10.1002/slct.201900076)
7.	Naoki Nakao, Masaharu Ueno, Shota Sakai, Daich Egawa, Hiroyuki Hanzawa, Shohei Kawasaki, Keigo Kumagai, Makoto Suzuki, Shu Kobayashi and Kentaro Hanada : Natural ligand-nonmimetic inhibitors of the lipid-transfer protein CERT. (N.N., M.U., and S.S. equally contributed to this study and are the co-first authors), Communications Chemistry, Vol.2, Articlenumber:20, 2019. (Summary) Lipid transfer proteins mediate inter-organelle transport of membrane lipids at organelle contact sites in cells, playing fundamental roles in the lipidome and membrane biogenesis in eukaryotes. We previously developed a ceramide-mimetic compound as a potent inhibitor of the ceramide transport protein CERT. Here we develop CERT inhibitors with structures unrelated to ceramide. To this aim, we identify a seed compound with no ceramide-like structure but with the capability of forming a hydrogen-bonding network in the ceramide-binding START domain, by virtual screening of ~3×106 compounds. We also establish a surface plasmon resonance-based system to directly determine the affinity of compounds for the START domain. Then, we subject the seed compound to a series of in silico docking simulations, efficient chemical synthesis, affinity analysis, protein-ligand co-crystallography, and various in vivo assays. This strategy allows us to obtain ceramide-unrelated compounds that potently inhibited the function of CERT in human cultured cells. (Tokushima University Institutional Repository) ● Metadata: 113055 (Link to Publication Site) ● Publication site (DOI): 10.1038/s42004-019-0118-3 (Link to Search Site for Scientific Articles) ● Search Scopus @ Elsevier (DOI): 10.1038/s42004-019-0118-3 (Tokushima University Institutional Repository: 113055, DOI: 10.1038/s42004-019-0118-3)
8.	Masaharu Ueno, Satoshi D. Ohmura, Makoto Wada and Norikazu Miyoshi : Aerobic oxidation of alcohols using bismuth bromide as a catalyst, Tetrahedron Letters, Vol.60, No.7, 570-573, 2019. (Summary) We developed an environmentally friendly method for aerobic oxidation of alcohols using a commercially available, relatively benign bismuth salt as a catalyst. We found that the catalytic combination of BiBr3 with nitric acid is key for enhancing the reactivity. The reaction proceeds well under air, making the use of pure oxygen unnecessary. Each of the primary or secondary alcohols tested was oxidized to the corresponding aldehydes or ketones using this protocol. (Tokushima University Institutional Repository) ● Metadata: 112992 (Link to Publication Site) ● Publication site (DOI): 10.1016/j.tetlet.2019.01.034 (Link to Search Site for Scientific Articles) ● Search Scopus @ Elsevier (DOI): 10.1016/j.tetlet.2019.01.034 (Tokushima University Institutional Repository: 112992, DOI: 10.1016/j.tetlet.2019.01.034)
9.	Masaharu Ueno, Kusaka Ryo, Satoshi D. Ohmura and Norikazu Miyoshi : Environmentally Benign Ritter Reaction Using Bismuth Salt as a Catalyst, European Journal of Organic Chemistry, Vol.2019, No.8, 1796-1800, 2019. (Summary) We developed the environmentally benign Ritter reaction using commercially available, less harmful bismuth salt as a catalyst. The reaction proceeded smoothly even using stoichiometric amount of nitrile to alcohol without any solvents. We also succeeded in establishing a purification process without using any organic solvents. (Tokushima University Institutional Repository) ● Metadata: 113060 (Link to Publication Site) ● Publication site (DOI): 10.1002/ejoc.201801882 (Link to Search Site for Scientific Articles) ● Search Scopus @ Elsevier (DOI): 10.1002/ejoc.201801882 (Tokushima University Institutional Repository: 113060, DOI: 10.1002/ejoc.201801882)
10.	Satoshi D. Ohmura, Masaharu Ueno and Norikazu Miyoshi : Strontium-mediated selective protonation of unsaturated linkage of aromatic hydrocarbons and these derivatives, Tetrahedron Letters, Vol.59, No.23, 2268-2271, 2018. (Keyword) Birch-like reduction / Strontium metal / Selective protonation / Aromatic hydrocarbons / Unsaturated linkage (Tokushima University Institutional Repository) ● Metadata: 113988 (Link to Publication Site) ● Publication site (DOI): 10.1016/j.tetlet.2018.04.074 (Link to Search Site for Scientific Articles) ● Search Scopus @ Elsevier (DOI): 10.1016/j.tetlet.2018.04.074 (Tokushima University Institutional Repository: 113988, DOI: 10.1016/j.tetlet.2018.04.074)
11.	Satoshi D. Ohmura, Yasuaki Miyazaki, Daisuke Kanehiro, Yuka Yamaguchi, Saki Kitakata, Sawa Tateda, Takahiro Nishizawa, Ryosuke Shimoda, Gen Nagaoka, Masaharu Ueno and Norikazu Miyoshi : Superior Alkylating Agents for Bulky Esters/Ketones via Strontium-Mediated Barbier-Type Reaction, Asian Journal of Organic Chemistry, Vol.6, No.7, 821-824, 2017. (Keyword) adamantanone / alkylation / Barbier-type reaction / ester / strontium (Link to Publication Site) ● Publication site (DOI): 10.1002/ajoc.201700209 (Link to Search Site for Scientific Articles) ● Summary page in Scopus @ Elsevier: 2-s2.0-85020473609 (DOI: 10.1002/ajoc.201700209, Elsevier: Scopus)
12.	Yuki Saito, Haruro Ishitani, Masaharu Ueno and Shu Kobayashi : Selective Hydrogenation of Nitriles to Primary Amines Catalyzed by a Polysilane/SiO₂-Supported Palladium atalyst unde Continuous-Flow Conditions, ChemistryOpen, Vol.6, No.2, 211-215, 2017. (Link to Publication Site) ● Publication site (DOI): 10.1002/open.201600166 (Link to Search Site for Scientific Articles) ● Search Scopus @ Elsevier (DOI): 10.1002/open.201600166 (DOI: 10.1002/open.201600166)
13.	Kobayashi Shu, Okumura Mikiko, Akatsuka Yuichi, Miyamura Hiroyuki, Masaharu Ueno and Oyamada Hidekazu : Powerful Continuous-Flow Hydrogenation by using Poly(dimethyl)silane-Supported Palladium Catalysts, ChemCatChem, Vol.7, No.24, 4025-4029, 2015. (Link to Publication Site) ● Publication site (DOI): 10.1002/cctc.201500973 (Link to Search Site for Scientific Articles) ● Summary page in Scopus @ Elsevier: 2-s2.0-84951883031 (DOI: 10.1002/cctc.201500973, Elsevier: Scopus)
14.	Masaharu Ueno, Yasuharu Morii, Kiyoko Uramoto, Hidekazu Oyamada, Yuichiro Mori and Shu Kobayashi : Catalytic Flow Hydrogenation of Aromatic Nitro Compounds Using Polysilane-Supported Palladium, Journal of Flow Chemistry, Vol.4, No.4, 160-163, 2014. (Link to Publication Site) ● Publication site (DOI): 10.1556/JFC-D-14-00024 (Link to Search Site for Scientific Articles) ● Search Scopus @ Elsevier (DOI): 10.1556/JFC-D-14-00024 (DOI: 10.1556/JFC-D-14-00024)
15.	Masaharu Ueno, Arata Tanoue and Shu Kobayashi : Catalytic Organic Reactions on the Surface of Silver(I) Oxide in Water, Chemistry Letters, Vol.43, No.12, 1867-1969, 2014. (Link to Publication Site) ● Publication site (DOI): 10.1246/cl.140818 (Link to Search Site for Scientific Articles) ● Search Scopus @ Elsevier (DOI): 10.1246/cl.140818 (DOI: 10.1246/cl.140818)
16.	Shū Kobayashi, Toshimitsu Endo, Takumi Yoshino, Uwe Schneider and Masaharu Ueno : Allylation reactions of aldehydes with allylboronates in aqueous media: unique reactivity and selectivity that are only observed in the presence of water., Chemistry - An Asian Journal, Vol.8, No.9, 2033-2045, 2013. (Summary) Zn(OH)2-catalyzed allylation reactions of aldehydes with allylboronates in aqueous media have been developed. In contrast to conventional allylboration reactions of aldehydes in organic solvents, the -addition products were obtained exclusively. A catalytic cycle in which the allylzinc species was generated through a B-to-Zn exchange process is proposed and kinetic studies were performed. The key intermediate, an allylzinc species, was detected by HRMS (ESI) analysis and by online continuous MS (ESI) analysis. This analysis revealed that, in aqueous media, the allylzinc species competitively reacted with the aldehydes and water. An investigation of the reactivity and selectivity of the allylzinc species by using several typical allylboronates (6a-6d) clarified several important roles of water in this allylation reaction. The allylation reactions of aldehydes with allylboronic acid 2,2-dimethyl-1,3-propanediol esters proceeded smoothly in the presence of catalytic amounts of Zn(OH)2 and achiral ligand 4d in aqueous media to afford the corresponding syn-adducts in high yields with high diastereoselectivities. In all cases, the -addition products were obtained and a wide substrate scope was tolerated. Furthermore, this reaction was applied to asymmetric catalysis by using chiral ligand 9. Based on the X-ray structure of the Zn-9 complex, several nonsymmetrical chiral ligands were also found to be effective. This reaction was further applied to catalytic asymmetric alkylallylation, chloroallylation, and alkoxyallylation processes and the synthetic utility of these reactions has been demonstrated. (Link to Publication Site) ● Publication site (DOI): 10.1002/asia.201300440 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 23775867 ● Search Scopus @ Elsevier (PMID): 23775867 ● Search Scopus @ Elsevier (DOI): 10.1002/asia.201300440 (DOI: 10.1002/asia.201300440, PubMed: 23775867)
17.	Masaharu Ueno, Yi-Yong Huang, Akihito Yamano and Shū Kobayashi : Revised stereochemistry of ceramide-trafficking inhibitor HPA-12 by X-ray crystallography analysis., Organic Letters, Vol.15, No.11, 2869-2871, 2013. (Summary) In response to Berkeš's report revising the stereochemistry of HPA-12, an important ceramide-trafficking inhibitor that was discovered and synthesized and its stereochemistry determined in 2001, the synthesis and the stereochemistry were reinvestigated. A large-scale synthetic method for HPA-12 based on a Zn-catalyzed asymmetric Mannich-type reaction in water was developed. Single crystals of HPA-12 for X-ray crystallographic analysis were obtained from ethyl propionate/n-hexane, and the stereochemistry was definitely determined to be 1R,3S, consistent with Berkeš's revised structure. (Keyword) Amides / Catalysis / Ceramides / X-ray crystallography / nuclear magnetic resonance spectroscopy / Models, Molecular / molecular structure / Stereoisomerism / zinc (Link to Publication Site) ● Publication site (DOI): 10.1021/ol401101u (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 23701643 ● Search Scopus @ Elsevier (PMID): 23701643 ● Search Scopus @ Elsevier (DOI): 10.1021/ol401101u (DOI: 10.1021/ol401101u, PubMed: 23701643)
18.	Shū Kobayashi, Pengyu Xu, Toshimitsu Endo, Masaharu Ueno and Taku Kitanosono : Chiral copper(II)-catalyzed enantioselective boron conjugate additions to ,-unsaturated carbonyl compounds in water., Angewandte Chemie International Edition, Vol.51, No.51, 12763-12766, 2012. (Link to Publication Site) ● Publication site (DOI): 10.1002/anie.201207343 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 23161846 ● Search Scopus @ Elsevier (PMID): 23161846 ● Search Scopus @ Elsevier (DOI): 10.1002/anie.201207343 (DOI: 10.1002/anie.201207343, PubMed: 23161846)
19.	Taku Kitanosono, Masaru Sakai, Masaharu Ueno and Shū Kobayashi : Chiral-Sc catalyzed asymmetric Michael addition/protonation of thiols with enones in water., Organic & Biomolecular Chemistry, Vol.10, No.35, 7134-7147, 2012. (Summary) Asymmetric Michael reactions and enantioselective protonations between enones and thiols were catalyzed by a Sc(OTf)(3)-chiral 2,2'-bipyridine complex in water. The remarkable governing of the enantioselectivity for simple introduction of protons despite their abnormally high mobility in water may provide us with new synthetic opportunities as well as significant chemical advances. (Link to Publication Site) ● Publication site (DOI): 10.1039/c2ob26264a (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 22850891 ● Search Scopus @ Elsevier (PMID): 22850891 ● Search Scopus @ Elsevier (DOI): 10.1039/c2ob26264a (DOI: 10.1039/c2ob26264a, PubMed: 22850891)
20.	Shū Kobayashi, Masaharu Ueno and Taku Kitanosono : Bismuth catalysts in aqueous media., Topics in Current Chemistry, Vol.311, 1-17, 2012. (Summary) Several bismuth-catalyzed synthetic reactions, which proceed well in aqueous media, are discussed. Due to increasing demand of water as a solvent in organic synthesis, catalysts that can be used in aqueous media are becoming more and more important. Although bismuth Lewis acids are not very stable in water, it has been revealed that they can be stabilized by basic ligands. Chiral amine and related basic ligands combined with bismuth Lewis acids are particularly useful in asymmetric catalysis in aqueous media. On the other hand, bismuth hydroxide is stable and works as an efficient catalyst for carbon-carbon bond-forming reactions in water. (Link to Publication Site) ● Publication site (DOI): 10.1007/128_2011_174 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 21769719 ● Search Scopus @ Elsevier (PMID): 21769719 ● Search Scopus @ Elsevier (DOI): 10.1007/128_2011_174 (DOI: 10.1007/128_2011_174, PubMed: 21769719)
21.	Shū Kobayashi, Toshimitsu Endo and Masaharu Ueno : Chiral zinc-catalyzed asymmetric -alkylallylation and -chloroallylation of aldehydes., Angewandte Chemie International Edition, Vol.50, No.51, 12262-12265, 2011. (Link to Publication Site) ● Publication site (DOI): 10.1002/anie.201106433 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 22025412 ● Search Scopus @ Elsevier (PMID): 22025412 ● Search Scopus @ Elsevier (DOI): 10.1002/anie.201106433 (DOI: 10.1002/anie.201106433, PubMed: 22025412)
22.	Masaharu Ueno, Taku Kitanosono, Masaru Sakai and Shū Kobayashi : Chiral Sc-catalyzed asymmetric Michael reactions of thiols with enones in water., Organic & Biomolecular Chemistry, Vol.9, No.10, 3619-3621, 2011. (Summary) Asymmetric Michael reactions of thiols with enones were catalyzed by a Sc(OTf)(3)-chiral bipyridine complex at room temperature in water without using any organic solvents, to afford the desired sulfides in high yields with high enantioselectivities. (Keyword) Alkenes / Catalysis / Ketones / Mesylates / Scandium / Stereoisomerism / Sulfhydryl Compounds / Water (Link to Publication Site) ● Publication site (DOI): 10.1039/c1ob05424d (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 21472183 ● Search Scopus @ Elsevier (PMID): 21472183 ● Search Scopus @ Elsevier (DOI): 10.1039/c1ob05424d (DOI: 10.1039/c1ob05424d, PubMed: 21472183)
23.	Shu Kobayashi, Taku Kitanosono and Masaharu Ueno : Copper(II) and Bismuth(III) Hydroxide Catalyzed Addition Reactions of Hydrazonoester with Allenylboronate in Aqueous Media, Synlett, Vol.2010, No.13, 2033-2036, 2010. (Link to Publication Site) ● Publication site (DOI): 10.1055/s-0030-1258485 (Link to Search Site for Scientific Articles) ● Search Scopus @ Elsevier (DOI): 10.1055/s-0030-1258485 (DOI: 10.1055/s-0030-1258485)
24.	Masaharu Ueno, Arata Tanoue and Shu Kobayashi : Silver Oxide as a Novel Catalyst for CarbonCarbon Bond-forming Reactions in Aqueous Media, Chemistry Letters, Vol.39, No.6, 652-653, 2010. (Link to Publication Site) ● Publication site (DOI): 10.1246/cl.2010.652 (Link to Search Site for Scientific Articles) ● Search Scopus @ Elsevier (DOI): 10.1246/cl.2010.652 (DOI: 10.1246/cl.2010.652)
25.	Shū Kobayashi, Toshimitsu Endo, Uwe Schneider and Masaharu Ueno : Aldehyde allylation with allylboronates providing alpha-addition products., Chemical Communications, Vol.46, No.8, 1260-1262, 2010. (Summary) Zn(OH)(2)-catalyzed allylation reactions of allylboronates with aldehydes proceeded smoothly in aqueous media; when alpha-substituted allylboronates were employed, the alpha-addition products were obtained exclusively, and syn-adducts were formed selectively in most cases; the use of Zn(OH)(2) with dmp (ligand) in aqueous media is the key to these reactions. (Keyword) Aldehydes / Allyl Compounds / Boronic Acids / Cyclization / Hydroxides / molecular structure / Zinc Compounds (Link to Publication Site) ● Publication site (DOI): 10.1039/b924527h (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 20449270 ● Search Scopus @ Elsevier (PMID): 20449270 ● Search Scopus @ Elsevier (DOI): 10.1039/b924527h (DOI: 10.1039/b924527h, PubMed: 20449270)
26.	Naiwei Wang, Tsutomu Matsumoto, Masaharu Ueno, Hiroyuki Miyamura and Shū Kobayashi : A gold-immobilized microchannel flow reactor for oxidation of alcohols with molecular oxygen., Angewandte Chemie International Edition, Vol.48, No.26, 4744-4746, 2009. (Summary) Golden capillaries: A gold-immobilized capillary column reactor allows oxidation of alcohols to carbonyl compounds using molecular oxygen. These capillary columns (see picture) can be used for at least four days without loss of activity. (Keyword) alcohols / Catalysis / Gold / oxidation and reduction / Oxygen (Link to Publication Site) ● Publication site (DOI): 10.1002/anie.200900565 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 19466725 ● Search Scopus @ Elsevier (PMID): 19466725 ● Search Scopus @ Elsevier (DOI): 10.1002/anie.200900565 (DOI: 10.1002/anie.200900565, PubMed: 19466725)
27.	Uwe Schneider, Masaharu Ueno and Shū Kobayashi : Catalytic use of indium(0) for carbon-carbon bond transformations in water: general catalytic allylations of ketones with allylboronates., Journal of the American Chemical Society, Vol.130, No.42, 13824-13825, 2008. (Summary) We have discovered the unprecedented catalytic use of In(0) for catalytic C-C bond transformations. Remarkably, these general catalytic allylations of ketones proceeded smoothly in water as a sole solvent under mild conditions, and water proved to be essential for these reactions. Both the displayed substrate scope and the functional group tolerance were excellent. Importantly, the In metal catalyst could be easily recovered and reused without loss of catalytic activity. Moreover, when an alpha-substituted allylboronate was used, an unusual constitutional selectivity was observed providing exclusively the formal alpha-adduct. Additionally, the resulting tertiary homoallylic alcohols were obtained with exceptionally high diastereoselectivities. The applicability of this concept to asymmetric catalysis in water by using In(0) combined with a chiral bis(oxazoline) ligand was demonstrated as well. (Keyword) alcohols / Alkylation / Allyl Compounds / Boronic Acids / Carbon / Catalysis / Indium / Ketones / molecular structure / Stereoisomerism / Water (Link to Publication Site) ● Publication site (DOI): 10.1021/ja804182j (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 18816118 ● Search Scopus @ Elsevier (PMID): 18816118 ● Search Scopus @ Elsevier (DOI): 10.1021/ja804182j (DOI: 10.1021/ja804182j, PubMed: 18816118)
28.	Tsutomu Matsumoto, Masaharu Ueno, Naiwei Wang and Shū Kobayashi : Immobilization of ruthenium in organic-inorganic hybrid copolymers: a reusable heterogeneous catalyst for oxidation of alcohols with molecular oxygen., Chemistry - An Asian Journal, Vol.3, No.2, 239-243, 2008. (Summary) A novel organic-inorganic hybrid ruthenium (HB Ru) catalyst for the oxidation of alcohols with molecular oxygen has been developed. The catalyst was prepared from a polystyrene-based copolymer, which includes a trimethoxysilyl functionality, and dichlorotris(triphenylphosphine)ruthenium, [RuCl2(PPh3)3], as the metal source. A sol-gel process was employed for heterogenization of the catalyst. The choice of both ruthenium species and trialkoxysilyl-bearing monomers was found to be important for high catalytic activity. In the presence of HB Ru corresponding to 5 mol % loading of ruthenium, the alcohols were oxidized with molecular oxygen or air at atmospheric pressure without any additives to afford the corresponding aldehydes or ketones in good to excellent yields. The catalyst could be recovered and reused at least five times without loss of activity. (Keyword) alcohols / Catalysis / Inorganic Chemicals / transmission electron microscopy / molecular structure / Organic Chemicals / oxidation and reduction / Oxygen / Polymers / Ruthenium (Link to Publication Site) ● Publication site (DOI): 10.1002/asia.200700336 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 18188860 ● Search Scopus @ Elsevier (PMID): 18188860 ● Search Scopus @ Elsevier (DOI): 10.1002/asia.200700336 (DOI: 10.1002/asia.200700336, PubMed: 18188860)
29.	Masaharu Ueno, Toshie Suzuki, Takeshi Naito, Hidekazu Oyamada and Shū Kobayashi : Development of microchannel reactors using polysilane-supported palladium catalytic systems in capillaries., Chemical Communications, No.14, 1647-1649, 2008. (Summary) A new method of immobilizing Pd catalysts on the channel wall of a capillary by using polysilane with metal oxide has been developed, and applied to hydrogenation reactions. (Keyword) Catalysis / Microchemistry / molecular structure / Oxides / Palladium / Polymers / Silanes / Surface Properties (Link to Publication Site) ● Publication site (DOI): 10.1039/b715259k (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 18368152 ● Search Scopus @ Elsevier (PMID): 18368152 ● Search Scopus @ Elsevier (DOI): 10.1039/b715259k (DOI: 10.1039/b715259k, PubMed: 18368152)
30.	Shu Kobayashi, Ryo Yazaki, Kazutaka Seki and Masaharu Ueno : An air-stable chiral Hf-based catalyst for asymmetric Mannich-type reactions, Tetrahedron, Vol.63, No.35, 3209-3213, 2007. (Link to Publication Site) ● Publication site (DOI): 10.1016/j.tet.2007.05.115 (Link to Search Site for Scientific Articles) ● Search Scopus @ Elsevier (DOI): 10.1016/j.tet.2007.05.115 (DOI: 10.1016/j.tet.2007.05.115)
31.	Tsutomu Matsumoto, Masaharu Ueno, Juta Kobayashi, Hiroyuki Miyamura, Yuichiro Mori and Shu Kobayashi : Polymer Incarcerated Ruthenium Catalyst for Oxidation of Alcohols with Molecular Oxygen, Advanced Synthesis & Catalysis, Vol.349, No.4-5, 531-534, 2007. (Link to Publication Site) ● Publication site (DOI): 10.1002/adsc.200600565 (Link to Search Site for Scientific Articles) ● Search Scopus @ Elsevier (DOI): 10.1002/adsc.200600565 (DOI: 10.1002/adsc.200600565)
32.	Kazutaka Seki, Masaharu Ueno and Shū Kobayashi : Storable, powdered chiral zirconium complex for asymmetric aldol and hetero Diels-Alder reactions., Organic & Biomolecular Chemistry, Vol.5, No.9, 1347-1350, 2007. (Summary) A storable, powdered chiral zirconium catalyst for asymmetric aldol and hetero Diels-Alder reactions has been developed. The catalyst has the same activity as that prepared in situ even after being stored for 3 months. Moreover, this chiral Zr catalyst worked efficiently not only for asymmetric aldol reactions but also for asymmetric hetero Diels-Alder reactions affording the corresponding addition products with high enantioselectivities. (Keyword) alcohols / Catalysis / Powders / Stereoisomerism / Time Factors / Zirconium (Link to Publication Site) ● Publication site (DOI): 10.1039/b701466j (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 17464402 ● Search Scopus @ Elsevier (PMID): 17464402 ● Search Scopus @ Elsevier (DOI): 10.1039/b701466j (DOI: 10.1039/b701466j, PubMed: 17464402)
33.	Shū Kobayashi, Jun Kobayashi, Ryo Yazaki and Masaharu Ueno : Toward the total synthesis of onchidin, a cytotoxic cyclic depsipeptide from a mollusc., Chemistry - An Asian Journal, Vol.2, No.1, 135-144, 2007. (Summary) The total synthesis of onchidin (1), a cytotoxic, C2-symmetric cyclic decadepsipeptide from a marine mollusc, according to the published structure, is described. A novel beta-amino acid, (2S,3S)-3-amino-2-methyl-7-octynoic acid (AMO), was efficiently prepared in high yield with high diastereo- and enantioselectivity based on a catalytic asymmetric three-component Mannich-type reaction with a chiral zirconium catalyst. The formation of sterically unfavorable N-methyl amide and hindered ester bonds were successfully demonstrated, and final macrocyclization was achieved at a secondary-amide site. Completion of the synthesis of 1 suggested that a revision of the structure of the natural product is required. Two diastereomers were also synthesized as candidates for the actual structure of onchidin. Furthermore, efficient solid-phase methods were employed for the combinatorial synthesis of other derivatives to clarify the real structure of onchidin. The solid-phase assembly of a pentadepsipeptide containing all the building blocks was established followed by dimeric cyclization in solution. (Keyword) Animals / Antineoplastic Agents / Catalysis / X-ray crystallography / Cyclization / Depsipeptides / Mannich Bases / Mollusca / Protein Conformation / Zirconium (Link to Publication Site) ● Publication site (DOI): 10.1002/asia.200600232 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 17441146 ● Search Scopus @ Elsevier (PMID): 17441146 ● Search Scopus @ Elsevier (DOI): 10.1002/asia.200600232 (DOI: 10.1002/asia.200600232, PubMed: 17441146)
34.	Takeshi Inasaki, Masaharu Ueno, Shinpei Miyamoto and Shu Kobayashi : Polymer-Incarcerated Palladium with Active Phosphine as Recoverable and Reusable Pd Catalyst for the Amination of Aryl Chlorides, Synlett, Vol.2007, No.10, 3209-3213, 2007. (Link to Publication Site) ● Publication site (DOI): 10.1055/s-2007-1000816 (Link to Search Site for Scientific Articles) ● Search Scopus @ Elsevier (DOI): 10.1055/s-2007-1000816 (DOI: 10.1055/s-2007-1000816)
35.	Yasuhiro Uozumi, A Yoichi M Yamada, Tomohiko Beppu, Naoshi Fukuyama, Masaharu Ueno and Takehiko Kitamori : Instantaneous carbon-carbon bond formation using a microchannel reactor with a catalytic membrane., Journal of the American Chemical Society, Vol.128, No.50, 15994-15995, 2006. (Summary) Instantaneous catalytic carbon-carbon bond forming reactions were achieved in a microchannel reactor having a polymeric palladium complex membrane. The catalytic membrane was constructed inside the microchannel via self-assembling complexation at the interface between the organic and aqueous phases flowing laminarly, where non-cross-linked polymer-bound phosphine and ammonium tetrachloropalladate dissolved, respectively. A palladium-catalyzed coupling reaction of aryl halides and arylboronic acids was performed using the microchannel reactor to give quantitative yields of biaryls within 4 s of retention time in the defined channel region. (Link to Publication Site) ● Publication site (DOI): 10.1021/ja066697r (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 17165726 ● Search Scopus @ Elsevier (PMID): 17165726 ● Search Scopus @ Elsevier (DOI): 10.1021/ja066697r (DOI: 10.1021/ja066697r, PubMed: 17165726)
36.	Shinya Matsuoka, Akihide Hibara, Masaharu Ueno and Takehiko Kitamori : Supercooled micro flows and application for asymmetric synthesis., Lab on a Chip, Vol.6, No.9, 1236-1238, 2006. (Summary) Supercooled micro flow in microchannels was demonstrated. In order to clarify fundamental properties of the supercooling state in microchannels, freezing temperature was measured in the microchannels having widths ranging from 70 microm to 300 microm. The freezing temperature decreased with decreasing width of the microchannel when the microchannel wall was chemically modified with octadecylsilane group. The lowest freezing temperature was observed as -28 degrees C for water in the 70 microm wide microchannel. By contrast, the freezing temperature was -15 degrees C and did not depend on width when a microchannel with a bare glass surface was used. Next, the freezing point was measured with flow rates ranging from 0.1 to 2.0 microl min(-1) and no dependence on flow rate was observed. Then, the supercooled micro flow was applied to an asymmetric reaction in micro two-phase flow of aqueous and CH2Cl2 phases. As expected from thermodynamic prediction, enantiomeric selectivity increased in the supercooled state of water. (Keyword) Catalysis / Ethyl Chloride / Freezing / Hydroxides / Microchip Analytical Procedures / Microfluidic Analytical Techniques / Molecular Structure / nanotechnology / Potassium Compounds / Surface Properties / Water (Link to Publication Site) ● Publication site (DOI): 10.1039/b602454h (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 16929404 ● Search Scopus @ Elsevier (PMID): 16929404 ● Search Scopus @ Elsevier (DOI): 10.1039/b602454h (DOI: 10.1039/b602454h, PubMed: 16929404)
37.	Yoshikuni Kikutani, Masaharu Ueno, Hideaki Hisamoto, Manabu Tokeshi and Takehiko Kitamoti : Continuous-flow chemical processing in three-dimensional microchannel network for on-chip integration of multiple reactions in a combinatorial mode, QSAR & Combinatorial Science, Vol.24, No.6, 742-757, 2005. (Link to Publication Site) ● Publication site (DOI): 10.1002/qsar.200540002 (Link to Search Site for Scientific Articles) ● Search Scopus @ Elsevier (DOI): 10.1002/qsar.200540002 (DOI: 10.1002/qsar.200540002)
38.	Akihide Hibara, Shinobu Iwayama, Shinya Matsuoka, Masaharu Ueno, Yoshikuni Kikutani, Manabu Tokeshi and Takehiko Kitamori : Surface modification method of microchannels for gas-liquid two-phase flow in microchips., Analytical Chemistry, Vol.77, No.3, 943-947, 2005. (Summary) A capillarity restricted modification method for microchannel surfaces was developed for gas--liquid microchemical operations in microchips. In this method, a microstructure combining shallow and deep microchannels and the principle of capillarity were utilized for chemical modification of a restricted area of a microchannel. A hydrophobic--hydrophilic patterning in microchannels was prepared as an example for guiding gas and liquid flows along the respective microchannels. Validity of the patterning was confirmed by measuring aqueous flow leak pressure from the hydrophilic microchannel to the hydrophobic one. The leak pressure of 7.7-1.1 kPa agreed well with that predicted theoretically from the Young-Laplace equation for the microchannel depth of 8.6-39 microm. In an experiment to demonstrate usefulness and effectiveness of the method, an air bubble was first introduced into the hydrophilic microchannel and purged from the hydrophobic-hydrophilic patterned microchannels. Next, the patterning structure was applied to remove dissolved oxygen by contacting the aqueous flow with a nitrogen flow. The concentration of dissolved oxygen decreased with contact time, and its time course agreed well with numerical simulation. These demonstrations showed that the proposed patterning method can be used in general microfluidic gas-liquid operations. (Keyword) Biomechanical Phenomena / Biotechnology / Equipment Design / Gases / Hydrophobic and Hydrophilic Interactions / Microchip Analytical Procedures / Microfluidic Analytical Techniques / nanotechnology / Nitrogen / Oxygen / Pressure / Rheology / Software / Surface Properties (Link to Publication Site) ● Publication site (DOI): 10.1021/ac0490088 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 15679365 ● Search Scopus @ Elsevier (PMID): 15679365 ● Search Scopus @ Elsevier (DOI): 10.1021/ac0490088 (DOI: 10.1021/ac0490088, PubMed: 15679365)
39.	Juta Kobayashi, Yuichiro Mori, Kuniaki Okamoto, Ryo Akiyama, Masaharu Ueno, Takehiko Kitamori and Shu Kobayashi : A microfluidic device for conducting gas-liquid-solid hydrogenation reactions., Science, Vol.304, No.5675, 1305-1308, 2004. (Summary) We have developed an efficient system for triphase reactions using a microchannel reactor. Using this system, we conducted hydrogenation reactions that proceeded smoothly to afford the desired products quantitatively within 2 minutes for a variety of substrates. The system could also be applied to deprotection reactions. We could achieve an effective interaction between hydrogen, substrates, and a palladium catalyst using extremely large interfacial areas and the short path required for molecular diffusion in the very narrow channel space. This concept could be extended to other multiphase reactions that use gas-phase reagents such as oxygen and carbon dioxide. (Link to Publication Site) ● Publication site (DOI): 10.1126/science.1096956 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 15166375 ● Search Scopus @ Elsevier (PMID): 15166375 ● Search Scopus @ Elsevier (DOI): 10.1126/science.1096956 (DOI: 10.1126/science.1096956, PubMed: 15166375)
40.	Shu Kobayashi, Masaharu Ueno, Susumu Saito, Yumiko Mizuki, Haruro Ishitani and Yasuhiro Yamashita : Air-stable, storable, and highly efficient chiral zirconium catalysts for enantioselective Mannich-type, aza Diels-Alder, aldol, and hetero Diels-Alder reactions., Proceedings of the National Academy of Sciences of the United States of America, Vol.101, No.15, 5476-5481, 2004. (Summary) For the synthesis of optically active compounds, chiral catalysts have attracted much attention because large quantities of optically active molecules can be prepared from a small amount of a chiral source. However, many chiral catalysts are often unstable in air (oxygen) and/or in the presence of water. This is especially the case in chiral Lewis acid catalysis, because most Lewis acids are air- and moisture-sensitive. Therefore, many catalysts are prepared in situ in an appropriate solvent just before use, and they cannot be stored for extended periods. We have developed air-stable, storable, and highly efficient chiral zirconium Lewis acids. The catalysts promoted asymmetric Mannich-type, aza Diels-Alder, aldol, and hetero Diels-Alder reactions efficiently with high enantioselectivities. A key to stabilizing the catalysts is an appropriate combination of chiral zirconium Lewis acids with molecular sieves, and the zirconium-molecular sieves-combined catalysts can be stored for extended periods in air at room temperature without loss of activity. Moreover, it has been demonstrated that the catalysts can be recovered and reused. (Link to Publication Site) ● Publication site (DOI): 10.1073/pnas.0307870101 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 15067139 ● Search Scopus @ Elsevier (PMID): 15067139 ● Search Scopus @ Elsevier (DOI): 10.1073/pnas.0307870101 (DOI: 10.1073/pnas.0307870101, PubMed: 15067139)
41.	Shu Kobayashi, Susumu Saito, Masaharu Ueno and Yasuhiro Yamashita : An air-stable, storable chiral zirconium catalyst for asymmetric aldol reactions., Chemical Communications, No.16, 2016-2017, 2003. (Summary) Asymmetric aldol reactions of ketene silyl acetals with aldehydes using an air-stable, storable chiral zirconium catalyst, which could be stored for at least 13 weeks at room temperature, proceeded smoothly to afford the desired adducts in high yields with high selectivity. (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 12934889 ● Summary page in Scopus @ Elsevier: 2-s2.0-0042567383 (PubMed: 12934889, Elsevier: Scopus)
42.	Masaharu Ueno, Hideaki Hisamoto, Takehiko Kitamorib and Shŭ Kobayashi : Phase-transfer alkylation reactions using microreactors., Chemical Communications, No.8, 936-937, 2003. (Summary) Phase-transfer alkylation in a microreactor proceeds smoothly, and the reaction has been found to be more efficient than that in a round-bottomed flask with vigorous stirring; we have observed by an optical microscope study that an interfacial area provided by organic and aqueous phases is more extended in a microreactor. (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 12744307 ● Summary page in Scopus @ Elsevier: 2-s2.0-0037459952 (PubMed: 12744307, Elsevier: Scopus)
43.	Yasuhiro Yamashita, Masaharu Ueno, Yokusu Kuriyama and Shu Kobayashi : Catalytic Asymmetric Mannich-Type Reactions Using a Novel Chiral Iron Complex, Advanced Synthesis & Catalysis, Vol.344, No.9, 929-931, 2002. (Link to Publication Site) ● Publication site (DOI): 10.1002/1615-4169(200210)344:9<929::aid-adsc929>3.0.co;2-z (Link to Search Site for Scientific Articles) ● Search Scopus @ Elsevier (DOI): 10.1002/1615-4169(200210)344:9<929::aid-adsc929>3.0.co;2-z (DOI: 10.1002/1615-4169(200210)344:9<929::aid-adsc929>3.0.co;2-z)
44.	Shu Kobayashi, Jun Kobayashi, Haruro Ishitani and Masaharu Ueno : Catalytic Enantioselective Addition of Propionate Units to Imines: An Efficient Synthesis of anti--Methyl--Amino Acid Derivatives, Chemistry - A European Journal, Vol.8, No.18, 4185-4190, 2002. (Link to Publication Site) ● Publication site (DOI): 10.1002/1521-3765(20020916)8:18<4185::aid-chem4185>3.0.co;2-6 (Link to Search Site for Scientific Articles) ● Search Scopus @ Elsevier (DOI): 10.1002/1521-3765(20020916)8:18<4185::aid-chem4185>3.0.co;2-6 (DOI: 10.1002/1521-3765(20020916)8:18<4185::aid-chem4185>3.0.co;2-6)
45.	Masaharu Ueno, Haruro Ishitani and shu Kobayashi : Air-Stable, Storable, and Highly Selective chiral Lewis Acid Catalyst, Organic Letters, Vol.4, No.20, 3395-3397, 2002. (Link to Publication Site) ● Publication site (DOI): 10.1021/ol026452t (Link to Search Site for Scientific Articles) ● Search Scopus @ Elsevier (DOI): 10.1021/ol026452t (DOI: 10.1021/ol026452t)
46.	Satoshi Yasuda, Hidetoshi Kitagawa, Masaharu Ueno, Haruro Iahitani, Masayoshi Fukasawa, Masahiro Nishijima, Shu Kobayashi and Kentaro Hanada : A Novel Inhibitor of Ceramide Trafficking from the Endoplasmic Reticulum to the Site of Sphingomyelin Synthesis, The Journal of Biological Chemistry, Vol.276, No.47, 43994-44002, 2001. (Summary) Ceramide produced at the endoplasmic reticulum (ER) is transported to the lumen of the Golgi apparatus for conversion to sphingomyelin (SM). N-(3-Hydroxy-1-hydroxymethyl-3-phenylpropyl)dodecanamide (HPA-12) is a novel analog of ceramide. Metabolic labeling experiments showed that HPA-12 inhibits conversion of ceramide to SM, but not to glucosylceramide, in Chinese hamster ovary cells. Cultivation of cells with HPA-12 significantly reduced the content of SM. HPA-12 did not inhibit the activity of SM synthase. The inhibition of SM formation by HPA-12 was abrogated when the Golgi apparatus was made to merge with the ER by brefeldin A. Moreover, HPA-12 inhibited redistribution of a fluorescent analog of ceramide, N-(4,4-difluoro-5,7-dimethyl-4-bora-3a,4a-diaza-s-indacene-3-pentanoyl)-d-erythro-sphingosine (C(5)-DMB-Cer), from intracellular membranes to the Golgi region. Among four stereoisomers of the drug, (1R,3S)-HPA-12, [corrected] which resembles natural ceramide stereochemically, was found to be the most active, although (1R,3S)-HPA-12 [corrected] did not affect ER-to-Golgi trafficking of protein. Interestingly, (1R,3S)-HPA-12 [corrected] inhibited conversion of ceramide to SM little in mutant cells defective in an ATP- and cytosol-dependent pathway of ceramide transport. These results indicated that (1R,3S)-HPA-12 [corrected] inhibits ceramide trafficking from the ER to the site of SM synthesis, possibly due to an antagonistic interaction with a ceramide-recognizing factor(s) involved in the ATP- and cytosol-dependent pathway. (Keyword) Amides / Animals / Biological Transport / CHO Cells / Ceramides / Cricetinae / Endoplasmic Reticulum / Glycosphingolipids / Golgi Apparatus / Sphingomyelins / Stereoisomerism (Link to Publication Site) ● Publication site (DOI): 10.1074/jbc.M104884200 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 11546801 ● Search Scopus @ Elsevier (PMID): 11546801 ● Search Scopus @ Elsevier (DOI): 10.1074/jbc.M104884200 (DOI: 10.1074/jbc.M104884200, PubMed: 11546801)
47.	Masaharu Ueno, Hidetoshi Kitagawa, Haruro Ishitani, Satoshi Yasuda, Kentaro Hanada and Shu Kobayashi : Catalytic enantioselective synthesis of a novel inhibitor of ceramide trafficking, (1R,3R)-N-(3-hydroxy-1-hydroxymethyl-3-phenylpropyl)dodecanamide (HPA-12), Tetrahedron Letters, Vol.42, No.44, 7863-7865, 2001.
48.	Shu Kobayashi, Haruro Ishitani, Yasuhiro Yamashita, Masaharu Ueno and Haruka Shimizu : A novel chiral zirconium catalyst for enantioselective aldol and Mannich-type reactions. Catalytic activation of both aldehydes and imines using a similar chiral Lewis acid, Tetrahedron, Vol.57, No.5, 861-866, 2001. (Link to Publication Site) ● Publication site (DOI): 10.1016/S0040-4020(00)01038-3 (Link to Search Site for Scientific Articles) ● Search Scopus @ Elsevier (DOI): 10.1016/S0040-4020(00)01038-3 (DOI: 10.1016/S0040-4020(00)01038-3)
49.	Haruro Ishitani, Masaharu Ueno and Shu Kobayashi : Enantioselective Mannich-Type Reactions Using a Novel Chiral Zirconium Catalyst for the Synthesis of Optically Active -Amino Acid Derivatives, Journal of the American Chemical Society, Vol.122, No.34, 8180-8186, 2000. (Link to Publication Site) ● Publication site (DOI): 10.1021/ja001642p (Link to Search Site for Scientific Articles) ● Search Scopus @ Elsevier (DOI): 10.1021/ja001642p (DOI: 10.1021/ja001642p)
50.	Shu Kobayashi, Masaharu Ueno, Ritsu Suzuki, Haruro Ishitani, Hye-Sook Kim and Yusuke Wataya : Catalytic Asymmetric Synthesis of Antimalarial Alkaloids Febrifugine and Isofebrifugine and Their Biological Activity., The Journal of Organic Chemistry, Vol.64, No.18, 6833-6841, 1999. (Summary) Antimalarial alkaloids febrifugine (1) and isofebrifugine (2) were efficiently synthesized from simple achiral starting materials on the basis of the catalytic asymmetric synthesis. The first key reaction was performed using the tin(II)-mediated catalytic asymmetric aldol protocol to afford chiral aldehyde 3 in high yield with high diastereo- and enantioselectivities. The second key step, a Mannich-type reaction, did not give satisfactory results according to the conventional methods. We then developed a novel aqueous Mannich-type three-component reaction of an aldehyde, an amine, and a vinyl ether using a Lewis acid-surfactant combined catalyst (LASC), and the key intermediates 16 and 17 were obtained in high yields. The final coupling reactions of bromoacetone 14 with 4-hydroxyquinazoline were carried out using basic conditions, and successive deprotection gave 1 and 2, respectively, without any isomerization. These unambiguous total asymmetric syntheses revealed that the absolute configurations of febrifugine and isofebrifugine were not (2'S,3'R) and (2'R,3'R) as reported previously but (2'R,3'S) and (2'S,3'S), respectively (1' and 2'). Finally, antimalarial activities of the synthesized febrifugine and isofebrifugine, and their antipodes, were examined. It was revealed that the activities and selectivities of natural febrifugine and isofebrifugine were much higher than those of the antipodes. (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 11674693 ● Search Scopus @ Elsevier (PMID): 11674693 (PubMed: 11674693)
51.	Shu Kobayashi, Masaharu Ueno, Ritsu Suzuki and Haruro Ishitani : Catalytic asymmetric synthesis of febrifugine and isofebrifugine, Tetrahedron Letters, Vol.40, No.11, 2175-2178, 1999. (Link to Publication Site) ● Publication site (DOI): 10.1016/S0040-4039(99)00142-2 (Link to Search Site for Scientific Articles) ● Search Scopus @ Elsevier (DOI): 10.1016/S0040-4039(99)00142-2 (DOI: 10.1016/S0040-4039(99)00142-2)
52.	Shu Kobayashi, Haruro Ishitani and Masaharu Ueno : Catalytic Asymmetric Synthesis of Both Syn- and Anti--Amino Alcohols, Journal of the American Chemical Society, Vol.120, No.2, 431-432, 1998. (Link to Publication Site) ● Publication site (DOI): 10.1021/ja973527t (Link to Search Site for Scientific Articles) ● Search Scopus @ Elsevier (DOI): 10.1021/ja973527t (DOI: 10.1021/ja973527t)
53.	Shu Kobayashi, Haruro Ishitani and Masaharu Ueno : Facile Synthesis of -Amino Nitriles Using Lanthanide Triflate as a Lewis Acid Catalyst, Synlett, No.1, 115-116, 1997. (Link to Publication Site) ● Publication site (DOI): 10.1055/s-1997-719 (Link to Search Site for Scientific Articles) ● Search Scopus @ Elsevier (DOI): 10.1055/s-1997-719 (DOI: 10.1055/s-1997-719)
54.	Haruro Ishitani, Masaharu Ueno and Shu Kobayashi : Catalytic Enantioselective Mannich-Type Reactions Using a Novel Chiral Zirconium Catalyst, Journal of the American Chemical Society, Vol.119, No.30, 7153-7154, 1997. (Link to Publication Site) ● Publication site (DOI): 10.1021/ja970498d (Link to Search Site for Scientific Articles) ● Search Scopus @ Elsevier (DOI): 10.1021/ja970498d (DOI: 10.1021/ja970498d)

Review, Commentary:

1.	Tsutomu Matsumoto, Masaharu Ueno, Naiwei Wang and Shū Kobayashi : Recent advances in immobilized metal catalysts for environmentally benign oxidation of alcohols., Chemistry - An Asian Journal, Vol.3, No.2, 196-214, Feb. 2008. (Summary) One of the most significant organic transformations in catalyst technology is the selective oxidation of alcohols. The acceleration of catalyst discovery in this field contributes to the economic and environmental impact in the production of useful materials. Heterogeneous catalysts combined with environmentally benign oxidants, such as molecular oxygen and hydrogen peroxide, are major challenges of exploratory research in the oxidation of alcohols. A wide range of recoverable catalysts has now emerged for these oxidation reactions. In this Focus Review, we present an overview of recent developments in immobilized metal catalysts and evaluate the potential of transition metals in the heterogeneously catalyzed oxidation of alcohols. (Keyword) alcohols / Catalysis / hydrogen peroxide / Metals / oxidation and reduction / Oxygen (Link to Publication Site) ● Publication site (DOI): 10.1002/asia.200700359 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 18232022 ● Search Scopus @ Elsevier (PMID): 18232022 ● Search Scopus @ Elsevier (DOI): 10.1002/asia.200700359 (DOI: 10.1002/asia.200700359, PubMed: 18232022)
2.	Masaharu Ueno, 火原彰秀 and 北森武彦 : マイクロ化学, 表面科学, Vol.26, No.2, 74-81, Feb. 2005.
3.	Masaharu Ueno and 北森武彦 : プレパラートが工場に!集積化マイクロ化学システムの現状と展望, 月刊マテリアルステージ, Vol.39, No.6, 107-113, Jun. 2004.
4.	渡慶次学, 火原彰秀, Masaharu Ueno, 佐藤記一 and 北森武彦 : 超微量分析・精密加工を可能にするマイクロ化学チップ, NEW GLASS, Vol.19, No.3, 5-13, Mar. 2004.
5.	北森武彦 and Masaharu Ueno : マイクロ空間を利用した化学—微小にするメリットとは?, 化学, Vol.59, No.2, 66-67, Feb. 2004.

Proceeding of International Conference:

1.	Masaharu Ueno : Methods of Incorporating Catalysts into Microchannels Based on Structure and Function and Their Application to Organic Synthesis, 2023 International Workshop on Microfluidic Chemical Plant International University-Industry Collaboration for Innovation, March 13-14 2023, Hsinchu, Taiwan, Keynote Lecture, Mar. 2023.
2.	Kobatake Miho, Norikazu Miyoshi and Masaharu Ueno : Total synthesis of Riccardin C using one-pot tandem coupling reactions, The 2021 International Chemical Congress of Pacific Basin Societies (Pacifichem), Honolulu Hawaii, USA (Online), Honolulu Hawaii, USA, Dec. 2021.
3.	Masaharu Ueno, Kazuki Tani and Norikazu Miyoshi : Development of Multicomponent, One-pot Sonogashira-Suzuki Tandem Coupling Reaction in Water, The 2021 International Chemical Congress of Pacific Basin Societies (Pacifichem), Honolulu Hawaii, USA, Honolulu Hawaii, USA, Dec. 2021.
4.	Sakai Shota, Nakao Naoki, Masaharu Ueno, Egawa Daichi, Hanzawa Hiroyuki, Kawasaki Shohei, Kumagai Keigo, Suzuki Makoto, Kobayashi Shu and Hanada Kentaro : Natural Ligand-nonmimetic inhibitors of the lipid-transfer protain CERT, The 60th International Conference on the Bioscience of Lipids(ICBL2019). 17-21 June 2019, Tokyo, Japan, Tokyo, Jun. 2019.
5.	Sakai Shota, Nakao Naoki, Masaharu Ueno, Egawa Daichi, Hanzawa Hiroyuki, Kawasaki Shohei, Kumagai Keigo, Suzuki Makoto, Kobayashi Shu and Hanada Kentaro : Natural ligand-nonmimetic inhibitors of the lipid-transfer protein CERT, The 60th International Conference on the Bioscience of Lipids (ICBL2019), Tokyo, Japan, Tokyo, Jun. 2019. (Summary) Lipid transfer proteins mediate inter-organelle transport of membrane lipids at organelle contact sites in cells, playing fundamental roles in the lipidome and membrane biogenesis in eukaryotes. We previously developed a ceramide-mimetic compound as a potent inhibitor of the ceramide transport protein CERT. Here we develop CERT inhibitors with structures unrelated to ceramide. To this aim, we identify a seed compound with no ceramide-like structure but with the capability of forming a hydrogen-bonding network in the ceramide-binding START domain, by virtual screening of ~3 × 106 compounds. We also establish a surface plasmon resonance-based system to directly determine the affinity of compounds for the START domain. Then, we subject the seed compound to a series of in silico docking simulations, efficient chemical synthesis, affinity analysis, protein-ligand co-crystallography, and various in vivo assays. This strategy allows us to obtain ceramide-unrelated compounds that potently inhibited the function of CERT in human cultured cells. (Keyword) Materials Chemistry / biochemistry / environmental chemistry / General Chemistry (Link to Publication Site) ● Publication site (DOI): 10.1038/s42004-019-0118-3 (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1050282812960984448 ● Summary page in Scopus @ Elsevier: 2-s2.0-85068715630 (DOI: 10.1038/s42004-019-0118-3, CiNii: 1050282812960984448, Elsevier: Scopus)
6.	Endo Toshimitsu, Masaharu Ueno and Kobayashi Shu : Asymmetric -Selective Allylaton of Aldehydes Catalyzed by Chirel Zinc-Bipyridine Complexes in Aqueous Media, The 3rd Asia-Oceania Conference on Green and Sustainable Chemistry (AOC-3). 4-7 December 2011, Melbourne, Australia, abs#234, Dec. 2011.
7.	Kitanosono Taku, Masaharu Ueno and Kobayashi Shu : Design and Development of Multifunctional Catalyst for Asymmetric Aldol Reactions in Water, The 3rd Asia-Oceania Conference on Green and Sustainable Chemistry (AOC-3). 4-7 December 2011, Melbourne, Australia, abs#211, Dec. 2011.
8.	Tanoue Arata, Masaharu Ueno and Kobayashi Shu : Silver Oxide as a Novel Catalyst for CarbonCarbon Bond-Forming Reactions in Aqueous Media, The 2010 International Chemical Congress of Pacific Basin Societies (Pacifichem). 15-20 December 2010, Honolulu Hawaii, USA, #805, Dec. 2010.
9.	Endo Toshimitsu, Masaharu Ueno and Kobayashi Shu : Metal Hydroxide-Catalyzed, Highly Stereoselective -Addition-type Allylation Reactions of Allylboronates with Aldehydes in Aqueous Media, The 6th International Forum on Chemistry of Functional Organic Chemicals (IFOC-6). 15-16 November 2009 The University of Tokyo Japan, P-25, Nov. 2009.
10.	Masaharu Ueno, Wang Naiwei, Matsumoto Tsutomu, Miyamura Hiroyuki and Kobayashi Shu : Gold-Immobilized Microchannel Flow Reactor for Oxidation of Alcohols with Molecular Oxygen, 16th European Symposium on Organic Chemistry (ESOC 2009). 12-16 July 2009 the Municipal House, Prague, Czech Republic, P2 218, Jul. 2009.
11.	Endo Toshimitsu, Masaharu Ueno and Kobayashi Shu : Metal Hydroxide-Catalyzed Highly Stereoselective Formal -addition-type Allylation Reactions of Aldehydes in Aqueous Media, 16th European Symposium on Organic Chemistry (ESOC 2009). 12-16 July 2009 the Municipal House, Prague, Czech Republic, P1 127, Jul. 2009.
12.	Hibara Akihide, Matsuoka Shinya, Masaharu Ueno and Kitamori Takehiko : Fundemental Properties of Micro Supercooling Flow, 10th International Conference on Miniaturized Systems for Chemistry and Life Sciences (TAS2006). 5-9 November 2006 Tokyo International Forum, Tokyo, Japan, 1794, Nov. 2006.
13.	Nakagawa Junichi, Tamaki Eiichiro, Masaharu Ueno, Tsukahara Takehiko, Hibara Akihide, Kim Haeng-Boo and Kitamori Takehiko : Enzymatic Reactions in extended-nano space utilizing pressure-driven flow control system, Fifth International Symposium on Microchemistry and Microsystem (ISMM2005). 1-2 December 2005 Kyoto TERRSA, Japan, PI-08, Dec. 2005.
14.	Matsuoka Shinya, Hosoda Kosuke, Masaharu Ueno, Hibara Akihide and Kitamori Takehiko : Phase Separation of Organic-aqueous Droplets and Segmented Mixed Phase Flows by Using Capillarity Restricted Surface Modification, 9th International Conference on Miniaturized Systems for Chemistry and Life Sciences (TAS2005). 9-13 October 2005 Boston Marriott Copley Place, Boston, USA, W28A, Oct. 2005.
15.	Nieuwland J. Pieter, Koch Kasper, Masaharu Ueno, Kitamori Takehiko, Hest C. M. van Jan and Rutjes P. J. T. Floris : MULTI-PHASE TWO-STEP SYNTHESIS IN MICROREACTORS, 9th International Conference on Miniaturized Systems for Chemistry and Life Sciences (TAS2005). 9-13 October 2005 Boston Marriott Copley Place, Boston, USA, W123E, Oct. 2005.
16.	Koch Kasper, Berg J. F. van den Rutger, Nieuwland J. Pieter, Masaharu Ueno, Kitamori Takehiko, Rutjes P. J. T. Floris and Hest C. M. van Jan : IMPROVED MULTI-PHASE ENZYMATIC SYNTHESIS IN A MICROCHANNEL, 9th International Conference on Miniaturized Systems for Chemistry and Life Sciences (TAS2005). 9-13 October 2005 Boston Marriott Copley Place, Boston, USA, T125E, Oct. 2005.
17.	Kobayashi Yusuke, Masaharu Ueno, Kobayashi Shu and Kitamori Takehiko : Development of a new method to immobilize of catalysts by surface modification in microspace, 8th International Conference on Miniaturized Systems for Chemistry and Life Sciences (TAS2004). 27-30 September 2004 Malmö Exhibition and Convention Center Malmö, Sweden, T-118-F, Sep. 2004.
18.	Okafuji Daiyu, Hisamoto Hideaki, Masaharu Ueno and Kitamori Takehiko : DEVELOPMENT OF NEW METHOD OF SURFACE MODIFICATION OF MICROCHANNELS, 8th International Conference on Miniaturized Systems for Chemistry and Life Sciences (TAS2004). 27-30 September 2004 Malmö Exhibition and Convention Center Malmö, Sweden, T-117-F, Sep. 2004.
19.	Masaharu Ueno, Moriya Shinta, Hisamoto Hideaki, Nakai Takeshi, Uozumi Yasuhiro and Kitamori Takehiko : SUZUKI-COUPLING REACTION USING PALLADIUM IMMOBILIZED MEMBRANE MICROCHIP, 8th International Conference on Miniaturized Systems for Chemistry and Life Sciences (TAS2004). 27-30 September 2004 Malmö Exhibition and Convention Center Malmö, Sweden, T-16-A, Sep. 2004.
20.	Hibara Akihide, Iwayama Shinobu, Masaharu Ueno, Kikutani Yoshikuni, Tokeshi Manabu and Kitamori Takehiko : Capillary-Restricted Microchannel Modification Method for Gas/Liquid Separation and Gas Bubble Purge, 8th International Conference on Miniaturized Systems for Chemistry and Life Sciences (TAS2004). 27-30 September 2004 Malmö Exhibition and Convention Center Malmö, Sweden, T-47-B, Sep. 2004.
21.	Kobayashi Juta, Mori Yuichiro, Masaharu Ueno, Kitamori Takehiko and Kobayashi Shu : DEVELOPMENT OF EFFECTIVE TRIPHASE REACTIONS USING MICROCHANNEL REACTORS, 8th International Conference on Miniaturized Systems for Chemistry and Life Sciences (TAS2004). 27-30 September 2004 Malmö Exhibition and Convention Center Malmö, Sweden, M-79-B, Sep. 2004.
22.	Matsuoka Shinya, Masaharu Ueno and Kitamori Takehiko : ORGANIC SYNTHETIC REACTIONS IN SUPERCOOLING FLOW USING MICROCHANNELS, 8th International Conference on Miniaturized Systems for Chemistry and Life Sciences (TAS2004). 27-30 September 2004 Malmö Exhibition and Convention Center Malmö, Sweden, M-54-B, Sep. 2004.
23.	Hibara Akihide, Iwayama Shinobu, Masaharu Ueno, Tokesh Manabu, Kikutani Yoshikuni and Kitamori Takehiko : Novel Surface Modification Method for Gas-Liquid Micro Unit Operations in Glass Microchips, 17th International Symposium on Microscale Separations and Capillary Electrophoresis (HPCE2004). 8-12 February 2004 Salzburg Congress, Salzburg, Austria, Feb. 2004.
24.	Okafuji Daiyu, Hisamoto Hideaki, Masaharu Ueno and Kitamori Takehiko : New synthetic method of the Functional Space in Microchannel by Chemical Modification, International Symposium on Microchemistry and Microsystem 2003 (ISMM2003). 18 November 2003 Waseda University Japan, P-09, Nov. 2003.
25.	Kobayashi Juta, Mori Yuichiro, Masaharu Ueno, Kitamori Takehiko and Kobayashi Shu : Development of Effective Triphase Reactions Using Palladium-Immobilized Microreactors, THE FOURTH INTERNATIONAL FORUM ON CHEMISTRY OF FUNCTIONAL ORGANIC CHEMICALS (IFOC-4). 16-17 November 2003 The University of Tokyo Japan, P-75, Nov. 2003.
26.	Masaharu Ueno, Hisamoto Hideaki, Kitamori Takehiko and Kobayashi Shu : Phase Transfer Alkylation Reactions Using Microchipreactors, THE FOURTH INTERNATIONAL FORUM ON CHEMISTRY OF FUNCTIONAL ORGANIC CHEMICALS (IFOC-4). 16-17 November 2003 The University of Tokyo Japan, P-74, Nov. 2003.
27.	Moriya Shinta, Masaharu Ueno, Hisamoto Hideaki and Kitamori Takehiko : The Fabrication of the Micro-membrane Supporting Catalyst for Organic Synthesis, THE FOURTH INTERNATIONAL FORUM ON CHEMISTRY OF FUNCTIONAL ORGANIC CHEMICALS (IFOC-4). 16-17 November 2003 The University of Tokyo Japan, P-73, Nov. 2003.
28.	Okafuji Daiyu, Hisamoto Hideaki, Masaharu Ueno and Kitamori Takehiko : New Functional Space in Microchannel for Nylon Syntheses by Chemicak Modification, THE FOURTH INTERNATIONAL FORUM ON CHEMISTRY OF FUNCTIONAL ORGANIC CHEMICALS (IFOC-4). 16-17 November 2003 The University of Tokyo Japan, P-72, Nov. 2003.
29.	Masaharu Ueno : Phase-Transfer Alkylation Reactions Using Microreactor, 1st Korea-Japan Symposium on Microsystem for Life Science and Chemistry (1st KJSMLC) October 30, 2003 KAIST, Daejeon, Korea, Oct. 2003.
30.	Masaharu Ueno and Kobayashi Shu : A Chiral Zirconium Catalyst Combined with Molecular Sieves Powder (ZiP). A Novel Chiral Catalyst That Can be Stored for More Than Three Monthes, 14th International Conference on Organic Synthesis (ICOS). 14-18 July 2002 Christchurch New Zealand, P-59, Jul. 2000.

Proceeding of Domestic Conference:

1.	KAMADA Chisato, Ryosuke Shimoda, Masaharu Ueno and Norikazu Miyoshi : ストロンチウムアルコキシド触媒を用いる簡便かつ有用なエステル交換反応の開発, 日本化学会第104春季年会,日本大学理工学部(千葉),公演番号 E1111-4pm-04, Mar. 2024.
2.	Tatsuya Watanabe, Masaharu Ueno and Norikazu Miyoshi : 金属ストロンチウムを用いるアミド化合物のアルデヒドへの還元反応, 日本化学会第104春季年会,日本大学理工学部(千葉),公演番号 E1111-4pm-03, Mar. 2024.
3.	Masaharu Ueno, TASHIMA Miku and Norikazu Miyoshi : 大量供給を志向した新規セラミド輸送タンパク質阻害剤HPCB-5の合成研究, 日本化学会第104春季年会,日本大学理工学部(千葉),公演番号 E1143-2pm-08, Mar. 2024.
4.	MIYOSHI Aki, Satoshi D. Ohmura, Norikazu Miyoshi and Masaharu Ueno : 環境調和型ワンポット・タンデムカップリング反応を用いた光機能性化合物の効率的合成及びその評価, 日本化学会第104春季年会,日本大学理工学部(千葉),公演番号 E1143-2pm-02, Mar. 2024.
5.	MIYOSHI Aki, Miho Kobatake, Norikazu Miyoshi and Masaharu Ueno : ワンポット・タンデムカップリング反応を駆使した天然物Riccardin類の効率的かつ網羅的合成法の開発, 日本化学会第104春季年会,日本大学理工学部(千葉),公演番号 E1143-2am-02, Mar. 2024.
6.	AKI Miyoshi, Satoshi D. Ohmura and Masaharu Ueno : 水中ワンポットタンデムカップリング反応を駆使したソルバトクロミズムを発現する機能性化合物の網羅的合成, 2023年度第2回日本プロセス化学会東四国地区フォーラムセミナー, P-12, Jan. 2024.
7.	TASHIMA Miku and Masaharu Ueno : カラム精製を用いない新規セラミド輸送タンパク質阻害剤HPCB-5のグラムスケール合成研究, 2023年度第2回日本プロセス化学会東四国地区フォーラムセミナー, P-11, Jan. 2024.
8.	Tatsuya Watanabe, Satoshi D. Ohmura, Masaharu Ueno and Norikazu Miyoshi : Reduction of amides with strontium metal, 日本化学会第103春季年会,東京理科大学(千葉),公演番号 K404-4pm-06, 2023年3月., Mar. 2023.
9.	AKI Miyoshi, Norikazu Miyoshi and Masaharu Ueno : Environmentally benign and efficient one-pot synthesis of polyaryl compounds by the tandem coupling reaction controlled on reaction temperatures, 日本化学会第103春季年会,東京理科大学(千葉),公演番号 P4-2am-33, 2023年3月., Mar. 2023.
10.	Kohki Kimura, Norikazu Miyoshi and Masaharu Ueno : ビスマス塩を触媒とするアルデヒドの環境調和型酸化反応の開発, 2022年日本化学会中国四国支部大会,広島大学(広島),講演番号2PB-11, Nov. 2022.
11.	Yu Kawakami, Norikazu Miyoshi and Masaharu Ueno : セラミド輸送阻害剤HPA-12類縁体の効率的合成, 2022年日本化学会中国四国支部大会,広島大学(広島),講演番号2PB-10, Nov. 2022.
12.	AKI Miyoshi, Kazuki Tani, Norikazu Miyoshi and Masaharu Ueno : ワンポットタンデムカップリング反応によるポリアリール化合物の環境調和型効率的合成, 2022年日本化学会中国四国支部大会,広島大学(広島),講演番号2K-10, Nov. 2022.
13.	Aki Miyoshi, Yasuaki Miyazaki, Shigeki Kubo, Masaharu Ueno and Norikazu Miyoshi : 金属ストロンチウムを用いる新しい形のシリルエーテル化反応の開発, 日本化学会第102春季年会,オンライン開催,公演番号 D202-4pm-07, Mar. 2022.
14.	Miho Kobatake, Norikazu Miyoshi and Masaharu Ueno : Riccardin Cの全合成をモデルとした効率的なワンポットタンデムカップリング反応の研究-ユニット合成の簡便さを考慮した適切な炭素-炭素切断位置及び組み合わせる官能基の設計-, 日本化学会第102春季年会,オンライン開催,公演番号 K5-2am-04, Mar. 2022.
15.	中尾直樹, Masaharu Ueno, 酒井祥太, 江川大地, 半沢宏之, 川崎祥平, 熊谷圭悟, 鈴木誠, 小林修 and 花田賢太郎 : 非天然骨格を有するCERT阻害剤のSBDD研究, 日本薬学会第141年会,広島国際会議場(広島), Mar. 2021.
16.	Masaharu Ueno, TANAKA Takumi, Satoshi D. Ohmura and Norikazu Miyoshi : 照射波長によるスチルバゾール類光異性化/環化反応の厳密な制御, 日本化学会第101春季年会,オンライン開催,公演番号 A17-4am-08, Mar. 2021.
17.	Hiroaki Nakamura, Haruka Takahashi, Masaharu Ueno and Norikazu Miyoshi : 金属ストロンチウムを用いたアセチレン骨格を複数持つ化合物を構築することによる短工程多置換イソベンゾフラノン合成手法の開発, 日本化学会第101春季年会,オンライン開催,公演番号 A15-1vn-10, Mar. 2021.
18.	Taiga Noda, Shohdai Kimura, Shigeki Kubo, Masaharu Ueno, Satoshi D. Ohmura and Norikazu Miyoshi : 金属ストロンチウムを用いる種々のアミド化合物への半アルキル化反応の応用, 日本化学会第101春季年会,オンライン開催,公演番号 A15-1vn-09, Mar. 2021.
19.	KOBATAKE Miho, Norikazu Miyoshi and Masaharu Ueno : ワンポットタンデムカップリング反応を用いた環境調和型Riccardin Cの全合成研究, 日本化学会第101春季年会,オンライン開催,公演番号 A19-2pm-06, Mar. 2021.
20.	Mami Fujita, Takahiro Nishizawa, Satoshi D. Ohmura, Masaharu Ueno and Norikazu Miyoshi : The covenient synthesis of functional silicic compounds via strontium-metallacycle intermediates and their photophysical properties with the substitution effects, 日本化学会第100春季年会, 東京理科大学(千葉), 公演番号3H8-49, Mar. 2020.
21.	Masaharu Ueno, Miho Kobatake, Satoshi D. Ohmura and Norikazu Miyoshi : Synthetic study of Riccardin C using one-pot tandem coupling reactions, 日本化学会第100春季年会, 東京理科大学(千葉), 公演番号3B5-10, Mar. 2020.
22.	Masaharu Ueno, Satoshi D. Ohmura and Norikazu Miyoshi : Study of the control of photoisomerization/aromatization of stilbazoles, 日本化学会第100春季年会, 東京理科大学(千葉), 公演番号1C4-46, Mar. 2020.
23.	Satoshi D. Ohmura, Taiga Noda, Masaharu Ueno and Norikazu Miyoshi : Luminescent properties of N-arylcarbazole derivatives with alkyl chains on the benzene ring, 日本化学会第100春季年会, 東京理科大学(千葉), 公演番号1C3-57, Mar. 2020.
24.	Taiga Noda, Satoshi D. Ohmura, Masaharu Ueno and Norikazu Miyoshi : N-アリールカルバゾール誘導体へのアルキル基の導入による立体効果に基づく発光特性変化の検討, 2019年度第3回日本プロセス化学会東四国地区フォーラムセミナー, Jan. 2020.
25.	Hiroaki Nakamura, Haruka Takahashi, Satoshi D. Ohmura, Masaharu Ueno and Norikazu Miyoshi : 多置換イソベンゾフラノン合成を指向した金属ストロンチウムを用いるアセチレン骨格を二つ以上持つ化合物の合成手法の検討, 2019年度第3回日本プロセス化学会東四国地区フォーラムセミナー, Jan. 2020.
26.	Taiga Noda, Satoshi D. Ohmura, Masaharu Ueno and Norikazu Miyoshi : N-アリールカルバゾール誘導体におけるアルキル基の導入による立体効果に基づく発光特性の検討, 2019年日本化学会中国四国支部大会, 徳島大学(徳島), 講演番号1P-029, Nov. 2019.
27.	Hiroaki Nakamura, Haruka Takahashi, Satoshi D. Ohmura, Masaharu Ueno and Norikazu Miyoshi : 多置換イソベンゾフラノン合成を指向した金属ストロンチウムを用いるアセチレン骨格を二つ持つ化合物の合成手法の検討, 2019年日本化学会中国四国支部大会, 徳島大学(徳島), 講演番号1P-026, Nov. 2019.
28.	Mami Fujita, Takahiro Nishizawa, Satoshi D. Ohmura, Masaharu Ueno and Norikazu Miyoshi : ストロンチウム-メタラサイクル中間体を用いた機能性ケイ素化合物を指向した簡便な合成手法の開発, 2019年日本化学会中国四国支部大会, 徳島大学(徳島), 講演番号1F-07, Nov. 2019.
29.	Kazuya Hirata, Satoshi D. Ohmura, Masaharu Ueno and Norikazu Miyoshi : A study of alkylation into N-atom contained disk-like molecules by using metallic strontium, 日本化学会第99春季年会, 甲南大学(兵庫), 講演番号3PC-057, Mar. 2019.
30.	Satoshi D. Ohmura, Shohdai Kimura, Masaharu Ueno and Norikazu Miyoshi : A study of transformation of carbonyl/amide moieties by metallic strontium as an electron source, 日本化学会第99春季年会, 甲南大学(兵庫), 講演番号3PC-056, Mar. 2019.
31.	Ryo Kusaka, Satoshi D. Ohmura, Norikazu Miyoshi and Masaharu Ueno : Development of environment friendly organic reactions using bismuth compounds as a catalyst, 日本化学会第99春季年会, 甲南大学(兵庫), 講演番号3PC-027, Mar. 2019.
32.	Masaharu Ueno, Mayu Okumura, Satoshi D. Ohmura and Norikazu Miyoshi : Study of the one-way photoisomerization of stilbazoles, 日本化学会第99春季年会, 甲南大学(兵庫), 講演番号1B4-42, Mar. 2019.
33.	Ryo Kusaka, Satoshi D. Ohmura, Norikazu Miyoshi and Masaharu Ueno : 有機ビスマスを含む協奏機能触媒を用いた新規カップリング反応の研究, 2018年日本化学会中国四国支部大会，愛媛大学城北キャンパス(愛媛)，講演番号2G-08, Nov. 2018.
34.	Yusuke Ishii, Takahiro Nishizawa, Sawa Tateda, Satoshi D. Ohmura, Masaharu Ueno and Norikazu Miyoshi : 金属ストロンチウムを用いる嵩高い含窒素化合物の合成手法の開発, 2018年日本化学会中国四国支部大会，愛媛大学城北キャンパス(愛媛)，講演番号2G-07, Nov. 2018.
35.	Shodai Kimura, Shigeki Kubo, Takahiro Nishizawa, Satoshi D. Ohmura, Masaharu Ueno and Norikazu Miyoshi : 金属ストロンチウムを用いるラジカル種の生成とその応用, 2018年日本化学会中国四国支部大会，愛媛大学城北キャンパス(愛媛)，講演番号1P-030, Nov. 2018.
36.	酒井祥太, 中尾直樹, Masaharu Ueno, 江川大地, 半沢宏之, 川崎祥平, 熊谷圭吾, 鈴木誠, 小林修 and 花田賢太郎 : Natural ligand non-mimetic inhibitors to the lipid-transfer protein CERT, 第91回日本生化学会大会，国立京都国際会館(京都)，講演番号1T14e(1P-369), Sep. 2018.
37.	Norikazu Miyoshi, Takahiro Nishizawa, Saki Kitakata, Satoshi D. Ohmura and Masaharu Ueno : ストロンチウム-メタラサイクル中間体の構造推定とその反応性に関する研究, 第29回基礎有機化学討論会，東京工業大学大岡山キャンパス(東京)，講演番号3C08, Sep. 2018.
38.	Satoshi D. Ohmura, Shodai Kimura, Shigeki Kubo, Masaharu Ueno and Norikazu Miyoshi : 金属ストロンチウムを反応剤として用いる選択的官能基変換, 第29回基礎有機化学討論会，東京工業大学大岡山キャンパス(東京)，講演番号1P106, Sep. 2018.
39.	Shodai Kimura, Shigeki Kubo, Satoshi D. Ohmura, Masaharu Ueno and Norikazu Miyoshi : Application and Development of Strontium-Mediated Alkylation of Amide Compounds, 日本化学会第98春季年会, 日本大学理工学部(千葉), 講演番号4H2-03, Mar. 2018.
40.	Kazuki Tani, Toshiki Hayashi, Satoshi D. Ohmura, Masaharu Ueno and Norikazu Miyoshi : Development of One-Pot Sonogashira-Suzuki Tandem Coupling Reaction in Water, 日本化学会第98春季年会, 日本大学理工学部(千葉), 講演番号2PC-122, Mar. 2018.
41.	Mami Fujita, 宮崎泰彰, Satoshi D. Ohmura, Masaharu Ueno and Norikazu Miyoshi : The Development of the New Synthetic Methods of Olefine Derivatives by Peterson Reaction Using Metallic Strontium, 日本化学会第98春季年会, 日本大学理工学部(千葉), 講演番号2PC-098, Mar. 2018.
42.	Yusuke Ishii, Sawa Tateda, Takahiro Nishizawa, Satoshi D. Ohmura, Masaharu Ueno and Norikazu Miyoshi : Application of Strontium-Mediated Alkylation of Nitrogen-Containing Compounds, 日本化学会第98春季年会, 日本大学理工学部(千葉), 講演番号2PC-097, Mar. 2018.
43.	Ryo Kusaka, Satoshi D. Ohmura, Norikazu Miyoshi and Masaharu Ueno : Study of the unique coupling reactions using the concerted bismuth catalysis, 日本化学会第98春季年会, 日本大学理工学部(千葉), 講演番号2H2-08, Mar. 2018.
44.	Mami Fujita, 宮崎泰彰, Satoshi D. Ohmura, Masaharu Ueno and Norikazu Miyoshi : 金属ストロンチウムを用いたアリルシランの新規合成法, 2017年日本化学会中国四国支部大会,鳥取産業体育館(鳥取),講演番号 OR54P, Nov. 2017.
45.	Kazuki Tani, Satoshi D. Ohmura, Norikazu Miyoshi and Masaharu Ueno : 薗頭-鈴木タンデムカップリング反応による水溶媒中でのワンポット多成分連結法の開発, 2017年日本化学会中国四国支部大会,鳥取産業体育館(鳥取),講演番号 OR44P, Nov. 2017.
46.	Masaharu Ueno : ビスマス塩を用いた環境にやさしい分子変換反応の開発, SCI-Tech Festival, Sep. 2017.
47.	Shodai Kimura, Shigeki Kubo, Satoshi D. Ohmura, Masaharu Ueno and Norikazu Miyoshi : Metallic Strontium-Mediated Monoalkylation of N,N-Dimethylamides, 64th Symposium on Organometallic Chemistry, Japan, Sep. 2017.
48.	Takahiro Nishizawa, Saki Kitakata, Sawa Tateda, Satoshi D. Ohmura, Masaharu Ueno and Norikazu Miyoshi : Preparation of Metallacycle Intermediates Using Metallic Strontium and Its Application for New Reaction, 64th Symposium on Organometallic Chemistry, Japan, Sep. 2017.
49.	Ryosuke Shimoda, Yasuaki Miyazaki, Satoshi D. Ohmura, Masaharu Ueno and Norikazu Miyoshi : Development of new synthetic method using strontium alkoxide, 28th Symposium on Physical Organic Chemistry, Sep. 2017.
50.	Satoshi D. Ohmura, Gen Nagaoka, Keisuke Yamana, Masaharu Ueno and Norikazu Miyoshi : Control of Luminescence Properties of Triarylamine Derivatives Based on Introduction of Alkyl Groups, 28th Symposium on Physical Organic Chemistry, Sep. 2017.
51.	Ryosuke Shimoda, 阿比留保奈美, 小松翔, Satoshi D. Ohmura, Masaharu Ueno and Norikazu Miyoshi : ストロンチウムアルコキシドを用いる新規合成手法の開発, 日本化学会第97春季年会, 慶應義塾大学日吉キャンパス(神奈川),講演番号 4D4-02, Mar. 2017.
52.	Takahiro Nishizawa, 北方咲, Satoshi D. Ohmura, Masaharu Ueno and Norikazu Miyoshi : 金属ストロンチウムを用いるメタラサイクル中間体の調製とそれを用いる新たな反応の開発, 日本化学会第97春季年会, 慶應義塾大学日吉キャンパス(神奈川),講演番号 4D4-01, Mar. 2017.
53.	Ryo Kusaka, Satoshi D. Ohmura, Norikazu Miyoshi and Masaharu Ueno : ビスマス塩を環境調和型触媒として用いるRitter反応の開発, 日本化学会第97春季年会, 慶應義塾大学日吉キャンパス(神奈川),講演番号 2E5-39, Mar. 2017.
54.	Masaharu Ueno, 喜多亜希子, 室井超帰, Satoshi D. Ohmura, Makoto Wada and Norikazu Miyoshi : ビスマス塩を触媒として用いた簡便かつ多様な酸化反応の開発, 日本化学会第97春季年会, 慶應義塾大学日吉キャンパス(神奈川),講演番号 2E5-38, Mar. 2017.
55.	Gen Nagaoka, Satoshi D. Ohmura, Masaharu Ueno and Norikazu Miyoshi : 発光特性を有するトリアリールアミン誘導体の合成とストロンチウム試剤を用いた置換基効果の検討, 日本化学会第97春季年会, 慶應義塾大学日吉キャンパス(神奈川),講演番号 2PC-060, Mar. 2017.
56.	Satoshi D. Ohmura, Masaharu Ueno and Norikazu Miyoshi : 金属ストロンチウムを用いるアミド化合物の還元反応, 日本化学会第97春季年会, 慶應義塾大学日吉キャンパス(神奈川),講演番号 1PB-111, Mar. 2017.
57.	Shodai Kimura, 久保誠輝, Satoshi D. Ohmura, Masaharu Ueno and Norikazu Miyoshi : 金属ストロンチウムを用いるアミド化合物のモノアルキル化反応, 日本化学会第97春季年会, 慶應義塾大学日吉キャンパス(神奈川),講演番号 1PB-110, Mar. 2017.
58.	Masaharu Ueno, 喜多亜希子, 室井超帰, Satoshi D. Ohmura, Makoto Wada and Norikazu Miyoshi : Development of the Aerobic Oxidation Reaction of Alcohols and Oxidative Esterification of Aldehydes Using Bismuth Salt as a Catalyst, The 49th Symposium on Chemical and Biological Oxidation, Nov. 2016.
59.	Ryo Kusaka, Satoshi D. Ohmura, Norikazu Miyoshi and Masaharu Ueno : ビスマス塩を触媒として用いるRitter反応の開発, 2016年日本化学会中国四国支部大会,香川大学(香川),講演番号 2P84, Nov. 2016.
60.	Takahiro NIshizawa, Saki Kitakata, Satoshi D. Ohmura, Masaharu Ueno and Norikazu Miyoshi : 金属ストロンチウムを用いるメタラサイクル中間体の合成とそれを用いた反応の開発, 2016年日本化学会中国四国支部大会,香川大学(香川),講演番号 1J13, Nov. 2016.
61.	Sawa Tateda, Satoshi D. Ohmura, Masaharu Ueno and Norikazu Miyoshi : ストロンチウムアミドを利用した合成手法の開発, 2016年日本化学会中国四国支部大会,香川大学(香川),講演番号 1J12, Nov. 2016.
62.	Keisuke Yamana, Satoshi D. Ohmura, Masaharu Ueno and Norikazu Miyoshi : Synthesis and Electronic Properties of Triarylamine Derivatives Oriented to Functional Materials, 第27回基礎有機化学討論会, 広島国際会議場(広島), 講演番号 2P084, Sep. 2016.
63.	Norikazu Miyoshi, Saki Kitakata, Sawa Tateda, Takahiro Nishizawa, Satoshi D. Ohmura and Masaharu Ueno : Study on Preparation and Reactivity of Sr-metallacycle Intermediates, 第27回基礎有機化学討論会, 広島国際会議場(広島), 講演番号 1C05, Sep. 2016.
64.	Masaharu Ueno : 実践的なグリーンケミストリーへの挑戦, 日本プロセス学会第20回プロセス化学東四国フォーラムセミナー, Jun. 2016.
65.	Masaharu Ueno, 喜多亜希子, 室井長帰, Satoshi D. Ohmura, Makoto Wada and Norikazu Miyoshi : Environmentally Benign Oxidation Reaction Using Bismuth Salt as a Catalyst, 日本化学会第96春季年会,同志社大学京田辺キャンパス(京都),講演番号 3H1-33, Mar. 2016.
66.	Satoshi D. Ohmura, Masaharu Ueno and Norikazu Miyoshi : Development of Sr-Mediated Hydrogenation of Aromatic Hydrocarbons, 日本化学会第96春季年会,同志社大学京田辺キャンパス(京都),講演番号 3H7-30, Mar. 2016.
67.	高橋春香, Satoshi D. Ohmura, Masaharu Ueno and Norikazu Miyoshi : Convenient Synthesis of Esters Having Two Different Acetylene Groups Using Acetylene Carboxylic Acid and Metallic Strontium, 日本化学会第96春季年会,同志社大学京田辺キャンパス(京都),講演番号 3H7-29, Mar. 2016.
68.	立田彩和, Satoshi D. Ohmura, Masaharu Ueno and Norikazu Miyoshi : Development of a new synthetic method using strontium amides, 日本化学会第96春季年会,同志社大学京田辺キャンパス(京都),講演番号 3PC-072, Mar. 2016.
69.	西澤高宏, Satoshi D. Ohmura, Masaharu Ueno and Norikazu Miyoshi : Preparation of Metallacycle Intermediates Using Metallic Strontium and Its Application for Strontium Acetylide, 日本化学会第96春季年会,同志社大学京田辺キャンパス(京都),講演番号 3PC-071, Mar. 2016.
70.	Haruka TAKAHASHI, Satoshi D. Ohmura, Masaharu Ueno and Norikazu Miyoshi : 金属ストロンチウムとアセチレンカルボン酸を用いる多置換イソベンゾフラノンの簡便合成手法の開発, 2015年日本化学会中国四国支部大会,岡山大学(岡山),講演番号 15EA04, Nov. 2015.
71.	Saki KITAKATA, Yasuaki MIYAZAKI, Hiroshi KUNI, Satoshi D. Ohmura, Masaharu Ueno and Norikazu Miyoshi : 金属ストロンチウムを用いた新たなメタラサイクル中間体の合成と新規合成手法の開発, 2015年日本化学会中国四国支部大会,岡山大学(岡山),講演番号 15EA03, Nov. 2015.
72.	Toshiki HAYASHI, Satoshi D. Ohmura, Norikazu Miyoshi and Masaharu Ueno : ワンポットタンデム薗頭/鈴木-宮浦カップリング反応を用いたポリアリール化合物の効率的合成手法の開発, 2015年日本化学会中国四国支部大会,岡山大学(岡山),講演番号 14P59, Nov. 2015.
73.	Takahiro NISHIZAWA, Yasuaki MIYAZAKI, Satoshi D. Ohmura, Masaharu Ueno and Norikazu Miyoshi : 金属ストロンチウムと共役ジエンを用いるメタラサイクルの調製とその応用, 2015年日本化学会中国四国支部大会,岡山大学(岡山),講演番号 14P57, Nov. 2015.
74.	Sawa TATEDA, Satoshi D. Ohmura, Masaharu Ueno and Norikazu Miyoshi : 有機ストロンチウムを塩基として用いる新規合成手法の開発, 2015年日本化学会中国四国支部大会,岡山大学(岡山),講演番号 14P55, Nov. 2015.
75.	Norikazu Miyoshi, Haruka TAKAHASHI, Satoshi D. Ohmura and Masaharu Ueno : 金属ストロンチウムとアセチレンカルボン酸エステルを用いる多置換イソベンゾフラノンの簡便合成法の開発, 第62回有機金属討論会,関西大学千里山キャンパス(大阪),講演番号 P3-01, Sep. 2015.
76.	Masaharu Ueno, 森井康晴, 小山田秀和 and 小林修 : ポリシラン-アルミナ固定化パラジウム触媒を用いるニトリルの連続フロー水素還元反応による一級アミン合成, 日本化学会第95春季年会,日本大学理工学部(千葉),講演番号 3D6-42, Mar. 2015.
77.	北之園拓, 大関喜朗, Masaharu Ueno and 小林修 : 水中での機能発現を志向した2,2'-ビピリジン骨格を有する多機能集約型触媒の開発, 日本化学会第95春季年会,日本大学理工学部(千葉),講演番号 1E1-37, Mar. 2015.
78.	Masaharu Ueno, 森井康晴, 浦本貴容子, 小山田秀和 and 小林修 : ポリシラン固定化パラジウム触媒を用いたニトロ化合物の連続フロー水素還元反応, 日本化学会第94春季年会,名古屋大学東山キャンパス(愛知),講演番号 1B9-34, Mar. 2014.
79.	吉野匠, Masaharu Ueno and 小林修 : 水酸化亜鉛固定化触媒を用いたアルデヒドのアリル化反応の開発とフロー合成への展開, 日本化学会第93春季年会，立命館大学びわこ・くさつキャンパス(滋賀)，講演番号 4E4-03, Mar. 2013.
80.	Masaharu Ueno, 遠藤俊充, 吉野匠, SCHNEIDER Uwe and 小林修 : 水酸化亜鉛を触媒として用いた含水溶媒中でのアリル化反応:水の存在下で起こる特異な有機反応, 日本化学会第93春季年会,立命館大学びわこ・くさつキャンパス(滋賀),講演番号 4E4-01, Mar. 2013.
81.	遠藤俊充, Masaharu Ueno and 小林修 : アンモニア水を窒素源として用いる触媒的不斉アリル位アミノ化反応の開発, 日本化学会第93春季年会，立命館大学びわこ・くさつキャンパス(滋賀)，講演番号 1E4-49, Mar. 2013.
82.	Masaharu Ueno, 伊達知晃 and 小林修 : 水系溶媒中でのケイ素のα,β-不飽和カルボニル化合物への不斉共役付加反応, 日本化学会第93春季年会，立命館大学びわこ・くさつキャンパス(滋賀)，講演番号 1E4-14, Mar. 2013.
83.	徐鵬宇, 北之園拓, 遠藤俊充, Masaharu Ueno and 小林修 : キラル銅(II)触媒を用いる水系溶媒中でのホウ素の不斉共役付加反応, 日本化学会第93春季年会，立命館大学びわこ・くさつキャンパス(滋賀)，講演番号 1E4-13, Mar. 2013.
84.	酒井克, 北之園拓, Masaharu Ueno and 小林修 : キラルスカンジウム触媒を用いる水中におけるチオールの不斉マイケル付加反応および不斉プロトン化反応, 日本化学会第92春季年会，慶應義塾大学日吉・矢上キャンパス(神奈川)，講演番号 4K6-17, Mar. 2012.
85.	北之園拓, Masaharu Ueno and 小林修 : 多機能集約型触媒を用いた水中に於ける直截的不斉ヒドロキシメチル化反応の開発, 日本化学会第92春季年会，慶應義塾大学日吉・矢上キャンパス(神奈川)，講演番号 4K6-16, Mar. 2012.
86.	吉野匠, 遠藤俊充, Masaharu Ueno and 小林修 : アリルホウ素を用いるアルデヒドのアリル化反応における溶媒効果, 日本化学会第92春季年会，慶應義塾大学日吉・矢上キャンパス(神奈川)，講演番号 3K5-30, Mar. 2012.
87.	Masaharu Ueno and 小林修 : 酸化銀(I)を触媒とするアリルケイ素を用いる水中でのアルデヒドのアリル化反応, 日本化学会第92春季年会，慶應義塾大学日吉・矢上キャンパス(神奈川)，講演番号 3K5-32, Mar. 2012.
88.	遠藤俊充, Masaharu Ueno and 小林修 : 水酸化亜鉛を触媒とする水系溶媒中でのアルデヒドのα-選択的アリル化反応の開発, 日本化学会第92春季年会，慶應義塾大学日吉・矢上キャンパス(神奈川)，講演番号 3K5-28, Mar. 2012.
89.	北之園拓, 酒井克, Masaharu Ueno and 小林修 : 水中での不斉炭素-炭素結合形成反応を指向した多機能触媒の設計と開発, 日本化学会第91春季年会，神奈川大学横浜キャンパス(神奈川)，講演番号 3C3-13, Mar. 2011.
90.	田上新, Masaharu Ueno and 小林修 : 酸化銀(I)を触媒とする水中でのアルデヒドに対するAntiおよびα-選択的アリル化反応, 日本化学会第91春季年会，神奈川大学横浜キャンパス(神奈川)，講演番号 3C3-12, Mar. 2011.
91.	遠藤俊充, Masaharu Ueno and 小林修 : キラルな水酸化亜鉛を触媒とする水系溶媒中でのアルデヒドのα-選択的不斉アリル化反応, 日本化学会第91春季年会，神奈川大学横浜キャンパス(神奈川)，講演番号 3C3-10, Mar. 2011.
92.	Masaharu Ueno and 小林修 : 新規表面修飾法による耐塩基性を持つ高分子触媒担持型マイクロキャピラリーリアクターの開発及び酸素酸化への応用, 第21回化学とマイクロ・ナノシステム研究会，東京大学小柴ホール(東京)，講演番号 P-088, Jun. 2010.
93.	田上新, Masaharu Ueno and 小林修 : スズから銀へのトランスメタル化を経由する水系溶媒中でのアルデヒドに対するAntiおよびα選択的アリル化反応, 日本化学会第90春季年会，近畿大学本部キャンパス(大阪)，講演番号 2F7-09A, Mar. 2010.
94.	遠藤俊充, Masaharu Ueno and 小林修 : 水酸化亜鉛を触媒として用いる水系溶媒中でのアルデヒドに対するSynおよびα-選択的アリル化反応の開発, 日本化学会第90春季年会，近畿大学本部キャンパス(大阪)，講演番号 2F7-08A, Mar. 2010.
95.	Masaharu Ueno and 小林修 : 金属水酸化物を触媒として用いるイミン等価体に対する水溶液中でのアリル化反応, 日本化学会第90春季年会，近畿大学本部キャンパス(大阪)，講演番号 1F7-44A, Mar. 2010.
96.	Masaharu Ueno, 北之園拓 and 小林修 : 水系溶媒中でのヒドラゾノエステルに対する高選択的アレニル及びプロパルギル付加反応の開発, 日本化学会第90春季年会，近畿大学本部キャンパス(大阪)，講演番号 1F7-43A, Mar. 2010.
97.	Masaharu Ueno and 小林修 : 水溶液中でのヒドラゾンに対する形式的α-付加型アリル化反応における触媒効果, 日本化学会第89春季年会，日本大学理工学部(千葉)，講演番号 4G2-19A, Mar. 2009.
98.	遠藤俊充, Masaharu Ueno and 小林修 : 金属水酸化物を触媒として用いる水系溶媒中でのアルデヒドに対する高立体選択的形式的α-付加型アリル化反応, 日本化学会第89春季年会，日本大学理工学部(千葉)，講演番号 4G2-19A, Mar. 2009.
99.	松山由香, Wang Naiwei, 松本努, Masaharu Ueno, 宮村浩之 and 小林修 : 金触媒担持マイクロキャピラリーリアクターを用いるアルコールの酸素酸化反応, 日本化学会第89春季年会，日本大学理工学部(千葉)，講演番号 3G3-25A, Mar. 2009.
100.	Masaharu Ueno, 間泰樹 and 小林修 : アリルスズを求核剤とするアシルヒドラゾンのアリル化反応の研究, 日本化学会第88春季年会，立教大学(東京)，講演番号 4J2-02A, Mar. 2008.
101.	Masaharu Ueno and 小林修 : 含水溶媒系のリガンド加速によるアリル化反応, 日本化学会第88春季年会，立教大学(東京)，講演番号 4J2-01A, Mar. 2008.
102.	Naiwei WANG, 松本努, Masaharu Ueno, 宮村浩之 and 小林修 : 金触媒担持キャピラリーリアクターを用いた多相系でのアルコールの酸素酸化反応, 日本化学会第88春季年会，立教大学(東京)，講演番号 2J1-13A, Mar. 2008.
103.	松本努, Masaharu Ueno, WANG Naiwei and 小林修 : 有機-無機ハイブリッド型ルテニウム触媒を用いるアルコールの酸素酸化反応の開発, 日本化学会第88春季年会，立教大学(東京)，講演番号 2J1-01A, Mar. 2008.
104.	Uwe Schneider, Masaharu Ueno and 小林修 : ケトンのアリル化反応．0価若しくは1価インジウムを活用したアリルボランの新規触媒的活性化法, 日本化学会第87春季年会，関西大学(大阪)，講演番号 3C6-37A, Mar. 2007.
105.	矢崎亮, Masaharu Ueno, 猿橋康一郎 and 小林修 : キラルジルコニウム触媒の新規高分子担持法, 日本化学会第87春季年会，関西大学(大阪)，講演番号 2C6-38A, Mar. 2007.
106.	関和貴, Masaharu Ueno and 小林修 : 保存可能キラルジルコニウム酸触媒を用いる不斉アルドール反応およびヘテロDiels-Alder反応, 日本化学会第87春季年会，関西大学(大阪)，講演番号 2C6-37A, Mar. 2007.
107.	鈴木淑恵, Masaharu Ueno, 小林重太, 内藤武詩, 小山田秀和 and 小林修 : ポリシラン担持型マイクロリアクターの開発, 日本化学会第87春季年会，関西大学(大阪)，講演番号 2C8-31A, Mar. 2007.
108.	島田朋夫, Masaharu Ueno, 森雄一郎 and 小林修 : フルオロカーボン鎖同士の相互作用を活用する新規高分子固定化ルイス酸触媒の開発, 日本化学会第87春季年会，関西大学(大阪)，講演番号 2C8-28A, Mar. 2007.
109.	松本努, Masaharu Ueno, 小林重太, 宮村浩之, 森雄一郎 and 小林修 : アルコールの酸素酸化反応を指向した高分子カルセランド型ルテニウム触媒の開発, 日本化学会第87春季年会，関西大学(大阪)，講演番号 2C8-27A, Mar. 2007.
110.	稲崎毅, Masaharu Ueno and 小林修 : ホスフィン配位子を有する高活性新規高分子カルセランド型パラジウム触媒, 日本化学会第87春季年会，関西大学(大阪)，講演番号 2C8-26A, Mar. 2007.
111.	Masaharu Ueno and 小林修 : 全ステップ含水溶媒環境下での抗マラリア剤Febrifugineの全合成, 日本化学会第87春季年会，関西大学(大阪)，講演番号 1C8-29B, Mar. 2007.
112.	Masaharu Ueno : 合成システムへの応用, 社団法人化学工学会第37回Continuing Educationシリーズ講習会「マイクロ科学技術の進展」，東京, Feb. 2007.
113.	松岡晋弥, Masaharu Ueno, 火原彰秀 and 北森武彦 : マイクロチャネル中での安定な過冷却流体の形成と不斉合成反応への応用, 日本化学会第86春季年会，日本大学理工学部(千葉)，講演番号 1J6-26B, Mar. 2006.
114.	小林悠介, Masaharu Ueno, 小林修 and 北森武彦 : フッ素の親和力を利用した触媒固定化法の開発と合成反応への応用, 第12回化学とマイクロ・ナノシステム研究会，京都テルサ(京都)，講演番号 PC-28, Dec. 2005.
115.	Masaharu Ueno : マイクロリアクタを用いる触媒反応, (財)相模中央研究所第2回触媒相模セミナー，神奈川, Nov. 2005.
116.	松岡晋弥, 火原彰秀, Masaharu Ueno and 北森武彦 : マイクロチャネルを用いた安定な過冷却流体の形成とその不斉反応への応用, 日本分析化学会第54年会，名古屋大学(名古屋)，講演番号 A2009, Sep. 2005.
117.	Masaharu Ueno : 集積化マイクロ化学チップの現状と展望, 東京大学科学知総合研究所会議，東京, Jul. 2005.
118.	松岡晋弥, 細田康介, Masaharu Ueno, 火原彰秀 and 北森武彦 : 毛管導入法を用いたセグメント多層流からの有機分離, 第11回化学とマイクロ・ナノシステム研究会，福岡国際会議場(福岡)，講演番号 P2-44, May 2005.
119.	Masaharu Ueno, 岡藤大雄 and 北森武彦 : マイクロチャネル壁面修飾法の開発と応用, 日本化学会第85春季年会，神奈川大学(横浜)，講演番号 3A5-07, Mar. 2005.
120.	火原彰秀, 岩山忍, Masaharu Ueno, 松岡晋弥, 菊谷善国, 渡慶次学 and 北森武彦 : 毛管現象を利用したマイクロチャネルの部分的化学修飾法とマイクロ気液プロセス, 第24回キャピラリー電気泳動シンポジウム，東北大学(仙台)，講演番号 P-3, Dec. 2004.
121.	松岡晋弥, Masaharu Ueno and 北森武彦 : 過冷却マイクロ流体の実現と不斉触媒反応への応用, 第10回化学とマイクロ・ナノシステム研究会,高松シンボルタワー(香川),講演番号 PB14, Nov. 2004.
122.	Masaharu Ueno, 守屋真太, 久本秀明, 中井康司, 魚住泰広 and 北森武彦 : マイクロチャネル内パラジウム触媒担持膜の作成と有機合成反応への展開, 第10回化学とマイクロ・ナノシステム研究会，高松シンボルタワー(香川)，講演番号 PC24, Nov. 2004.
123.	松岡晋弥, Masaharu Ueno and 北森武彦 : マイクロチャネルを用いた過冷却流体中での化学反応, 日本分析化学会第53年会，千葉工業大学(千葉)，講演番号 H2008, Sep. 2004.
124.	Masaharu Ueno, 火原彰秀, 岩山忍 and 北森武彦 : 毛細管現象を利用したマイクロチャネル部分修飾法の開発と気液制御マイクロ化学プロセスへの応用, 日本分析化学会第53年会，千葉工業大学(千葉)，講演番号 H2007, Sep. 2004.
125.	Masaharu Ueno : マイクロリアクター, 日本テクノセンター「マイクロタス(Micro Total Analysis Systemes)技術とその応用および今後の動向」，東京, Jul. 2004.
126.	小林悠介, Masaharu Ueno, 小林修 and 北森武彦 : フッ素の親和力を利用した触媒固定化法の開発とアルドール反応による評価, 第9回化学とマイクロ・ナノシステム研究会，京都大学(京都)，講演番号 P224, May 2004.
127.	酒井亮, 高橋豊, 吉田佳一, Masaharu Ueno and 北森武彦 : 両親媒性表面修飾による二相層流界面の安定化, 第9回化学とマイクロ・ナノシステム研究会，京都大学(京都)，講演番号 P118, May 2004.
128.	森雄一朗, 小林重太, Masaharu Ueno, 北森武彦 and 小林修 : マイクロリアクターを用いる効率的多相系反応の開発, 日本薬学会第124年会，大阪南港地区ATC(大阪)，講演番号【P2】I-242, Mar. 2004.
129.	小林重太, 森雄一朗, 秋山良, 岡本訓明, Masaharu Ueno, 北森武彦 and 小林修 : パラジウム固定化マイクロリアクターを用いる効率的三相系反応の開発, 日本化学会第84春季年会，関西学院大学(西宮)，講演番号 3K3-16, Mar. 2004.
130.	Masaharu Ueno, 岡藤大雄, 火原彰秀, 久本秀明 and 北森武彦 : 閉塞を抑止する新規マイクロチャネル壁面修飾法の開発, 日本化学会第84春季年会，関西学院大学(西宮)，講演番号 1A2-09, Mar. 2004.
131.	火原彰秀, 岩山忍, Masaharu Ueno and 北森武彦 : 毛細管現象利用マイクロチャネル部分修飾法と気液マイクロ化学プロセスへの応用, 日本化学会第84春季年会，関西学院大学(西宮)，講演番号 1A2-08, Mar. 2004.
132.	Masaharu Ueno : 機能性微小空間の創成と合成反応への応用, 第5回TMR技術検討会，東京, Dec. 2003.
133.	岡藤大雄, 久本秀明, Masaharu Ueno and 北森武彦 : マイクロチャネル壁面の新規修飾法の開発, 第8回化学とマイクロ・ナノシステム研究会，早稲田大学(東京)，講演番号 P2-42, Nov. 2003.
134.	岩山忍, Masaharu Ueno, 火原彰秀 and 北森武彦 : マイクロチャネル壁面の部分修飾を利用した気液の分離, 第8回化学とマイクロ・ナノシステム研究会，早稲田大学(東京)，講演番号 P2-41, Nov. 2003.
135.	酒井亮, 高橋豊, 吉田圭一, Masaharu Ueno and 北森武彦 : マイクロチップを用いた不斉エポキシ化反応, 第8回化学とマイクロ・ナノシステム研究会，早稲田大学(東京)，講演番号 P1-23, Nov. 2003.
136.	岡藤大雄, 久本秀明, Masaharu Ueno and 北森武彦 : ラジカル重合を利用したマイクロチャネルの壁面修飾, 日本分析化学会第52年会，宮城教育大学(仙台)，講演番号 2F07, Sep. 2003.
137.	Masaharu Ueno, 久本秀明, 小林修 and 北森武彦 : マイクロチャネル内における液/液界面間を利用したβ-ケトエステルのアルキル化反応, 日本分析化学会第52年会，宮城教育大学(仙台)，講演番号 2F06, Sep. 2003.
138.	Masaharu Ueno : マイクロリアクター, (財)神奈川科学技術アカデミー教育講座「集積化マイクロ化学システムコース」神奈川科学技術アカデミー(KAST), Jul. 2003.
139.	小林順, Masaharu Ueno, 石谷暖郎 and 小林修 : 新規β-アミノ酸の触媒的不斉合成を用いる環状デプシペプチドOnchidinの全合成研究, 日本化学会第83春季年会，早稲田大学(東京)，講演番号 3H504, Mar. 2003.
140.	Masaharu Ueno, 久本秀明, 北森武彦 and 小林修 : マイクロリアクターを用いるアルキル化反応, 日本化学会第83春季年会，早稲田大学(東京)，講演番号 2H402, Mar. 2003.
141.	Masaharu Ueno and 小林修 : 長期保存可能な新規ゼオライト固定化キラルジルコニウム触媒, 日本化学会第81春季年会，早稲田大学(東京)，講演番号 4GZ06, Mar. 2002.
142.	小林順, Masaharu Ueno, 石谷暖郎 and 小林修 : 新規キラルジルコニウム触媒用いるアンチ選択的不斉Mannich反応, 日本化学会第81春季年会，早稲田大学(東京)，講演番号 4GZ05, Mar. 2002.
143.	Masaharu Ueno, 石谷暖郎, 小林順 and 小林修 : 新規キラルジルコニウム触媒用いる不斉アザDiels-Alder反応, 日本化学会第79春季年会，甲南大学(兵庫)，講演番号 3G506, Mar. 2001.
144.	Masaharu Ueno, 石谷暖郎 and 小林修 : 新規キラルジルコニウム触媒を用いる不斉Mannich反応, 日本化学会第78春季年会，日本大学(千葉)，講演番号 2F327, Mar. 2000.
145.	鈴木律, Masaharu Ueno, 石谷暖郎 and 小林修 : 抗マラリア活性を有するアルカロイドfebrifugine類の合成研究(2), 日本化学会第76春季年会，神奈川大学(神奈川)，講演番号 1C128, Mar. 1999.
146.	Masaharu Ueno, 鈴木律, 石谷暖郎 and 小林修 : 抗マラリア活性を有するアルカロイドfebrifugine類の合成研究(1), 日本化学会第76春季年会，神奈川大学(神奈川)，講演番号 1C127, Mar. 1999.
147.	Masaharu Ueno, 石谷暖郎 and 小林修 : キラルなジルコニウム触媒を用いるβ-アミノアルコールの両ジアステレオマーの不斉合成, 日本化学会第74春季年会，同志社大学(京都)，講演番号 1D627, Mar. 1998.
148.	小林修, Masaharu Ueno and 石谷暖郎 : 希土類金属トリフラートを用いるStrecker反応, 日本化学会第72春季年会，立教大学(東京)，講演番号 4G134, Mar. 1997.

Patent:

1.	Katsuhiko Osaki, Shigeki Yamazaki, Takehiko Kitamori, Masaharu Ueno, Kazuma mawatari and Yoshikuni Kikutani : Microchip and microchip device used in evaporation operation method for synthesis of radioactive material, US2010-734384 (Apr. 2010), US20100247429 (Sep. 2010), .
2.	小林修 and Masaharu Ueno : 水系溶媒中での含窒素化合物の製造方法, 2010-53770 (Mar. 2010), 2011-184408 (Sep. 2011), 5184565 (Jan. 2013).
3.	小林修 and Masaharu Ueno : α付加型アリル化反応による選択的ホモアリルアルコール誘導体の製造法, 2009-60333 (Mar. 2009), 2010-215513 (Sep. 2010), 5372556 (Sep. 2013).
4.	Katsuhiko Osaki, Shigeki Yamazaki, Takehiko Kitamori, Masaharu Ueno, Kazuma mawatari and Yoshikuni Kikutani : Microchip and microchip device used in evaporation operation method for synthesis of radioactive material, EP2008-845767 (Oct. 2008), EP2218499 (Aug. 2010), .
5.	Katsuhiko Osaki, Shigeki Yamazaki, Takehiko Kitamori, Masaharu Ueno, Kazuma mawatari and Yoshikuni Kikutani : Microchip and microchip device used in evaporation operation method for synthesis of radioactive material, WO2008-JP69755 (Oct. 2008), WO2009057693 (May 2009), .
6.	Yasuhiro Uozumi, Yoichi Yamada, Naoshi Fukuyama, Tomohiko Beppu, Takehiko Kitamori and Masaharu Ueno : Microchannel reactors, US2008-281182 (Aug. 2008), US20090306414 (Dec. 2009), .
7.	曽我部敦, 那須昭夫, 北森武彦, Masaharu Ueno, 馬渡和真 and 菊谷善国 : 4-メトキシサリチル酸の合成方法, 2008-193540 (Jul. 2008), 2010-030940 (Feb. 2010), .
8.	小林修, ナイウェイワン, Masaharu Ueno, 松本努 and 宮村浩之 : キャピラリーとキャピラリーへの触媒固定化方法，並びにマイクロリアクターとこれを用いた固相-液相-気相反応方法, 200861923 (Mar. 2008), 2009214056 (Sep. 2009), 4978864 (Apr. 2012).
9.	小林修, Masaharu Ueno and 松本努 : 高分子固定化ルテニウム触媒及びその使用, 2008-055756 (Mar. 2008), 2009-208027 (Sep. 2009), .
10.	小林修, Masaharu Ueno and ウーベシュナイダー : ホモアリルアルコール又はホモアリルヒドラジドの製造方法, 2008-18887 (Jan. 2008), 2008255093 (Oct. 2008), 5072026 (Nov. 2012).
11.	大崎勝彦, 山崎茂樹, 北森武彦, Masaharu Ueno, 馬渡和真 and 菊谷善国 : マイクロチップ，マイクロチップデバイス及びマイクロチップを用いた蒸発操作方法, 2007-285012 (Nov. 2007), 2009106916 (May 2009), 5309312 (Oct. 2013).
12.	曽我部敦, 那須昭夫, 北森武彦, Masaharu Ueno, 馬渡和真 and 菊谷善国 : マイクロリアクターを用いた不飽和有機化合物の合成方法, 2007-136487 (May 2007), 2008-290958 (Dec. 2008), .
13.	小林修 and Masaharu Ueno : フェブリフジン及びイソフェブリフジンの新規製造方法, 2007-59111 (May 2007), 2008222566 (Sep. 2008), 4829152 (Dec. 2011).
14.	小林修, 関和貴 and Masaharu Ueno : 固体キラルジルコニウム触媒及びそれを用いたアルドール反応物又は環化体化合物の合成方法, 2007-51428 (May 2007), 2008212792 (Sep. 2008), 4696274 (Jan. 2011).
15.	小林修, Masaharu Ueno and 猿橋康一郎 : 高分子担持キラルジルコニウム触媒の製造方法, 2007-61132 (Mar. 2007), 2008222803 (Sep. 2008), 5180493 (Apr. 2013).
16.	小林修, 鈴木淑恵, Masaharu Ueno, 小山田秀和 and 内藤武詩 : キャピラリー及びそれを用いたマイクロリアクター並びに該マイクロリアクターによる固相-液層-気相反応方法, 2007-61135 (Mar. 2007), 2008221094 (Sep. 2008), 4734544 (Jul. 2011).
17.	小林修, Masaharu Ueno and 島田朋生 : 含フッ素ポリマー固定化遷移金属触媒, 2007-060124 (Mar. 2007), 2008-221067 (Sep. 2008), .
18.	小林修, 稲崎毅 and Masaharu Ueno : 高分子固定化パラジウム触媒，及びその製造方法，並びに前記触媒を用いた反応方法, 2007-60817 (Mar. 2007), 2008221089 (Sep. 2008), 4701195 (Jan. 2011).
19.	Yasuhiro Uozumi, Yoichi Yamada, Naoshi Fukuyama, Tomohiko Beppu, Takehiko Kitamori and Masaharu Ueno : Microchannel reactors, EP2007-714976 (Feb. 2007), EP1990090 (Nov. 2008), .
20.	Yasuhiro Uozumi, Yoichi Yamada, Naoshi Fukuyama, Tomohiko Beppu, Takehiko Kitamori and Masaharu Ueno : Microchannel reactors, WO2007-JP53583 (Feb. 2007), WO2007099932 (Sep. 2007), .
21.	小林修, 松本努, Masaharu Ueno and 森雄一朗 : カルボニル化合物の製法, 2007-41957 (Feb. 2007), 2008201755 (Sep. 2008), 4925050 (Apr. 2012).
22.	Shu Kobayashi, Yuichiro Mori, Takehiko Kitamori, Masaharu Ueno and Kuniaki Okamoto : Method of catalytic hydrogenation or carbonylation reaction using micro-reactor having palladium polymer-supported on its inner walls of microchannels, US2006-587895 (Jul. 2006), US20070161834 (Jul. 2007), US7663008 (Feb. 2010).
23.	魚住泰広, 山田陽一, 福山尚志, 別府朋彦, 北森武彦 and Masaharu Ueno : マイクロチャンネルリアクター, 2006-56193 (Mar. 2006), 2008-502784 (Feb. 2007), 5162758 (Mar. 2013).
24.	Shu Kobayashi, Yuichiro Mori, Takehiko Kitamori, Masaharu Ueno and Kuniaki Okamoto : Method of catalytic hydrogenation or carbonylation reaction using micro-reactor having palladium polymer-supported on its inner walls of microchannels, EP2005-704332 (Jan. 2005), EP1726577 (Nov. 2006), EP1726577 (Nov. 2011).
25.	Shu Kobayashi, Yuichiro Mori, Takehiko Kitamori, Masaharu Ueno and Kuniaki Okamoto : Method of catalytic hydrogenation or carbonylation reaction using micro-reactor having palladium polymer-supported on its inner walls of microchannels, WO2005-JP1434 (Jan. 2005), WO2005073151 (Aug. 2005), .
26.	小林修, 森雄一朗, 北森武彦, Masaharu Ueno and 岡本訓明 : マイクロリアクターを用いた接触反応方法, 2005-517562 (Jan. 2005), WO2005073151 (Aug. 2005), 4605391 (Oct. 2010).
27.	北森武彦, 火原彰秀, Masaharu Ueno and 渡慶次学 : マイクロチャンネル内表面の部分化学修飾方法とマイクロチャンネル構造体, 2004-333789 (Nov. 2004), 2005169386 (Jan. 2005), 4523386 (Aug. 2010).
28.	酒井亮, 渡慶次学, Masaharu Ueno and 北森武彦 : マイクロ化学デバイス, 2004-148066 (May 2004), 2005331286 (Dec. 2005), 4460944 (May 2010).
29.	北森武彦, 火原彰秀, Masaharu Ueno and 渡慶次学 : マイクロチャンネル内壁面の化学修飾法, 2003-386000 (Nov. 2003), 2005144337 (Jan. 2005), 4230339 (Feb. 2009).

Grants-in-Aid for Scientific Research (KAKEN Grants Database @ NII.ac.jp)

Efficient synthesis of functional molecules by multicomponent tandem coupling reaction and application for flow synthesis (Project/Area Number: 19K05479 )
Development of the Continuous Microflow Reaction and Multi StepProcess (Project/Area Number: 23750099 )
Development of Catalyst Immobilized Micro Reactor for Combinatorial Multi Step Reactions (Project/Area Number: 21750091 )
マイクロ過冷却流体の実現と合成反応への展開 (Project/Area Number: 18710117 )
Investigation on high throughput chemical synthesis by utilizing micro chemical systems (Project/Area Number: 13124203 )
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Associate Professor : Ueno, Masaharu

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Grants-in-Aid for Scientific Research (KAKEN Grants Database @ NII.ac.jp)