Tokushima University / Educator and Researcher Directory --- Kasai, Asuka

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Tokushima University ⟩ University Hospital ⟩ Central Clinical Facilities ⟩ Surgical Center ⟩
Tokushima University ⟩ Faculty of Medicine ⟩ School of Medicine ⟩ Course of Biological Medicine ⟩ Anesthesiology ⟩
Tokushima University ⟩ University Hospital ⟩ Clinical Division ⟩ Department of Neurosurgery, Psychiatry and Anesthesiology ⟩ Anesthesiology ⟩

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Research

Field of Study

Subject of Study

Book / Paper

Academic Paper (Judged Full Paper):

1.	Michiko Kinoshita, Sarara Mutoh, Asuka Kasai, Ryosuke Kawanishi and Katsuya Tanaka : General Anesthesia in a Patient With Neuronal Intranuclear Inclusion Disease: A Case Report., A&A Practice, Vol.16, No.10, 2022. (Summary) Neuronal intranuclear inclusion disease (NIID) is a progressive neurodegenerative disease with diverse clinical manifestations, including dementia and muscle weakness. We summarize anesthetic considerations in reporting general anesthesia for a 58-year-old man with bladder dysfunction and cerebellar ataxia who was diagnosed with NIID. The patient developed postinduction hypotension relevant to autonomic neuropathy. The potential risks, such as prolonged reaction to neuromuscular blocking agent, postoperative delirium, and worsening of NIID-related symptoms, were also considered. The responsiveness to anesthetics may vary widely from case t case. As the number of NIID cases increases, a better understanding of NIID is needed. (Link to Publication Site) ● Publication site (DOI): 10.1213/XAA.0000000000001633 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 36599032 ● Search Scopus @ Elsevier (PMID): 36599032 ● Search Scopus @ Elsevier (DOI): 10.1213/XAA.0000000000001633 (DOI: 10.1213/XAA.0000000000001633, PubMed: 36599032)
2.	Naoji Mita, Shinji Kawahito, Shiho Satomi, Asuka Kasai, Tomohiro Soga, Yoko Sakai, Kazumi Takaishi, Hiroshi Kitahata, Yasuo Tsutsumi and Katsuya Tanaka : Ultrasound-guided Peripheral Nerve Block and General Anesthesia for Hepatectomy in a Patient with Chronic Inflammatory Demyelinating Polyneuropathy, Masui, Vol.68, No.4, 409-412, 2019. (Keyword) 慢性炎症性脱髄性多発根ニューロパチー(CIDP) / 全身麻酔 / 超音波ガイド下神経ブロック / 肝切除術 / chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) / general anesthesia / ultrasound-guided peripheral nerve block / hepatectomy (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1520009407524776192 (CiNii: 1520009407524776192)
3.	Nami Kakuta, Yasuo Tsutsumi, Chiaki Murakami, Yoko Sakai, Takuro Oyama, Asuka Kasai, Katsuyoshi Kume and Katsuya Tanaka : Effectiveness of using non-invasive continuous arterial pressure monitoring with ClearSight in hemodynamic monitoring during living renal transplantation in a recipient:a case report., The Journal of Medical Investigation : JMI, Vol.65, No.1.2, 139-141, 2018. (Summary) We investigated the effectiveness of the ClearSight system for hemodynamic management during kidney transplantation for a recipient. The recipient was to receive a kidney transplant from his mother under general anesthesia. We used continuous noninvasive finger-cuff-based monitoring of blood pressure, provided by the ClearSight system, and stroke volume variation to predict fluid responsiveness. We used of a balanced anesthetic technique and stringent monitoring standards to ensure a successful outcome for the patient. This case demonstrated that ClearSight has the potential to improve patient monitoring in hemodynamically stable patients who received kidney transplantation under general anesthesia. J. Med. Invest. 65:139-141, February, 2018. (Keyword) Adult / Arterial Pressure / Hemodynamic Monitoring / Humans / Kidney Transplantation / Male (Tokushima University Institutional Repository) ● Metadata: 111450 (Link to Publication Site) ● Publication site (DOI): 10.2152/jmi.65.139 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 29593185 ● Search Scopus @ Elsevier (PMID): 29593185 ● Search Scopus @ Elsevier (DOI): 10.2152/jmi.65.139 (Tokushima University Institutional Repository: 111450, DOI: 10.2152/jmi.65.139, PubMed: 29593185)
4.	Chiaki Murakami, Nami Kakuta, Katsuyoshi Kume, Yoko Sakai, Asuka Kasai, Takuro Oyama, Katsuya Tanaka and Yasuo Tsutsumi : A comparison of fosaprepitant and ondansetron for preventing postoperative nausea and vomiting in moderate to high risk patients: A retrospective database analysis., BioMed Research International, Vol.2017, 5703528, 2017. (Summary) Postoperative nausea and vomiting (PONV) occur in 30-50% of patients undergoing general anesthesia and in 70-80% of high PONV risk patients. In this study, we investigated the efficacy of fosaprepitant, a neurokinin-1 (NK1) receptor antagonist, compared to ondansetron, a selective 5-hydroxytryptamine type 3 (5-HT3) receptor antagonist, in moderate to high PONV risk patients from our previous randomized controlled trials. Patients (171 patients from 4 pooled studies) with the Apfel simplified score ≥ 2 and undergoing general anesthesia were randomly allocated to receive intravenous fosaprepitant 150 mg (NK1 group, = 82) and intravenous ondansetron 4 mg (ONS group, = 89) before induction of anesthesia. Incidence of vomiting was significantly lower in the NK1 group compared to the ONS group 0-2, 0-24, and 0-48 hours after surgery (2 versus 17%, 2 versus 28%, and 2 versus 29%, resp.). However, no significant differences in PONV, complete response, rescue antiemetic use, and nausea score were observed between groups 0-48 hours after surgery. In moderate to high PONV risk patients, fosaprepitant decreased the incidence of vomiting and was superior to ondansetron in preventing postoperative vomiting 0-48 hours after surgery. (Keyword) Adult / Aged / Aged, 80 and over / Databases as Topic / Demography / Humans / Middle Aged / Morpholines / Ondansetron / Postoperative Care / Postoperative Nausea and Vomiting / Retrospective Studies / Risk Factors / Young Adult (Tokushima University Institutional Repository) ● Metadata: 112392 (Link to Publication Site) ● Publication site (DOI): 10.1155/2017/5703528 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 29410964 ● Search Scopus @ Elsevier (PMID): 29410964 ● Search Scopus @ Elsevier (DOI): 10.1155/2017/5703528 (Tokushima University Institutional Repository: 112392, DOI: 10.1155/2017/5703528, PubMed: 29410964)
5.	Shiho Satomi, Asuka Kasai, Eisuke Hamaguchi, Yasuo Tsutsumi and Katsuya Tanaka : Normothermic Cardiopulmonary Bypass in Patient with Waldenstroms Macroglobulinemia and Cryoglobulinemia: A Case Report., A & A Case Reports, Vol.9, No.6, 162-163, 2017. (Summary) Waldenström's macroglobulinemia (WM) manifests as hyperviscosity syndrome. Cryoglobulinemia, which may increase blood viscosity or induce thrombosis in association with decreased body temperature, can occur in combination with WM. We describe the management of an 82-year-old woman with WM, hyperviscosity syndrome, and cryoglobulinemia who required open aortic valve replacement. Decreased body temperature in this patient was prevented during cardiopulmonary bypass by using a forced air warming system and normothermic cardioplegia with continuous warm blood cardioplegia perfusion. (Keyword) Aged, 80 and over / Aortic Valve / Cardiopulmonary Bypass / Cryoglobulinemia / Female / Heart Valve Prosthesis / Humans / Treatment Outcome / Waldenstrom Macroglobulinemia (Link to Publication Site) ● Publication site (DOI): 10.1213/XAA.0000000000000555 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 28520564 ● Summary page in Scopus @ Elsevier: 2-s2.0-85042463059 (DOI: 10.1213/XAA.0000000000000555, PubMed: 28520564, Elsevier: Scopus)

Review, Commentary:

1.	Katsuya Tanaka, Asuka Kasai and Takuro Oyama : PART2 術前合併症アップデート胃切除・食道切除術後患者, LiSA, Vol.27, No.2, 157-162, Sep. 2020. (Link to Publication Site) ● Publication site (DOI): 10.11477/mf.3104200166 (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1390853649577523072 ● Search Scopus @ Elsevier (DOI): 10.11477/mf.3104200166 (DOI: 10.11477/mf.3104200166, CiNii: 1390853649577523072)

Proceeding of International Conference:

1.	Asuka Kasai, Kouhei Fukuta, Katsuya Tanaka, Nami Kakuta and Yasuo Tsutsumi : The effect of intraoperative glucose load on metabolism in patients with diabetes mellitus., American Society of Anesthesiologists 2017 Annual Meeting, Oct. 2017.
2.	Kouhei Fukuta, Asuka Kasai, Katsuya Tanaka, Yoko Sakai and Yasuo Tsutsumi : The Influence of Glucose Load on Metabolism in Elderly Patients During Surgery Using Remifentanil-induced Anesthesia, American Society of Anesthesiologists 2017 Annual Meeting, Oct. 2017.
3.	Takuro Oyama, Nami Kakuta, Asuka Kasai, Naoji Mita, Katsuyoshi Kume and Katsuya Tanaka : Effect of Jelly type carbohydrate on metabolism and evaluation of its excretion in healthy subjects., American Society of Anesthesiologists 2017 Annual Meeting, Oct. 2017.

Proceeding of Domestic Conference:

1.	Yuki Maeda, Nami Kakuta, Asuka Kasai, Ryosuke Kawanishi and Katsuya Tanaka : Eisenmenger症候群患者の腹腔鏡下子宮全摘術の麻酔経験第44回日本循環制御医学会, Jul. 2023.
2.	曽我朋宏, Asuka Kasai, 箕田直治, 川人伸次 and Katsuya Tanaka : 高度側弯，広範囲脊椎固定術後のSMA患者に対するヌシネルセン投与を複数回行った症例, 日本ペインクリニック学会第56回学術集会, Jul. 2022.
3.	Asuka Kasai, 曽我朋宏 and Katsuya Tanaka : トラマドール製剤の長期投与中に性腺機能不全を認めた1症例, 日本ペインクリニック学会第56回学術集会, Jul. 2022.
4.	Tomohiro Soga, Shinji Kawahito, Asuka Kasai, Naoji Mita, Kazumi Takaishi, 木下浩之 and Katsuya Tanaka : 冠攣縮性狭心症を合併した妊婦に対する硬膜外無痛分娩の1症例, 第42回日本循環制御医学会総会・学術集会, Jul. 2021.
5.	Yoshinobu Tomiyama, Ryosuke Kawanishi and Asuka Kasai : 腹腔鏡胸腔鏡手術時間の年次推移, 日本手術医学会誌, Vol.41, No.Supplement, 164, Sep. 2019.
6.	Yoshinobu Tomiyama, Ryosuke Kawanishi, Asuka Kasai, Yuki Ishikawa and 板東悠太郎 : Factors that influence the time from end of surgery to operating room exi, 麻酔, Vol.67, May 2019.
7.	里見志帆, Asuka Kasai, 木下浩之, Shinji Kawahito and Katsuya Tanaka : 常温血性心筋保護持続冠潅流による開心術の麻酔経験, 第38回日本循環制御医学会, Jun. 2017.
8.	Asuka Kasai, Kouhei Fukuta, Nami Kakuta, Yasuo Tsutsumi and Katsuya Tanaka : 糖尿病患者におけるレミフェンタニル麻酔と糖負荷が代謝に与える影響, 日本麻酔科学会第64回学術集会, Jun. 2017.
9.	Kouhei Fukuta, Asuka Kasai, Yoko Sakai, Yasuo Tsutsumi and Katsuya Tanaka : 高齢者におけるレミフェンタニル麻酔と糖負荷が代謝に与える影響, 日本麻酔科学会第64回学術集会, Jun. 2017.

Grants-in-Aid for Scientific Research (KAKEN Grants Database @ NII.ac.jp)

Cardiac protection by volatile anesthetic -Role of sirtuine and autophagy regulation- (Project/Area Number: 19K18244 )
Anesthetic preconditioning against ischemia-reperfusion injury on mitochondrial dynamics (Project/Area Number: 17K16735 )
Volatile anesthetic and GLP-1 induced cardiac protection synergism is dependent on the activation of autophagy. (Project/Area Number: 15H06448 )
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