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Tokushima University ⟩ University Hospital ⟩ Clinical Division ⟩ Department of Internal Medicine ⟩ Respiratory and Rheumatology Medicine ⟩
Tokushima University ⟩ Faculty of Medicine ⟩ School of Medicine ⟩ Course of Bioregulation and Medical Oncology ⟩ Respiratory Medicine and Rheumatology ⟩ 		(Files for researchmap) [PDF manual] [Auto-propagate to researchmap]

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Academic Paper (Judged Full Paper):

1. Hiroyuki Kozai, Hirokazu Ogino, Atsushi Mitsuhashi, Thi Na Nguyen, Yuki Tsukazaki, Yohei Yabuki, Ryohiko Ozaki, Hiroto Yoneda, Seidai Satou, Masaki Hanibuchi, Tsutomu Shinohara, Hiroshi Nokihara and Yasuhiko Nishioka :
Potential of fluoropyrimidine to be an immunologically optimal partner of immune checkpoint inhibitors through inducing immunogenic cell death for thoracic malignancies.,
Thoracic Cancer, Vol.15, No.5, 369-378, 2024.
(Tokushima University Institutional Repository: 119383,   DOI: 10.1111/1759-7714.15200,   PubMed: 38146645)
2. Hiroki Takahashi, Hirokazu Ogino, Hiroki Bando, Atsushi Mitsuhashi, Yuki Tsukazaki, Yohei Yabuki, Ryohiko Ozaki, Hiroto Yoneda, Seidai Satou, Masaki Hanibuchi and Yasuhiko Nishioka :
FoundationOne CDx detected an uncovered variant of epidermal growth factor receptor exon 19 deletion by Oncomine Dx target test in a patient with lung adenocarcinoma.,
Respiratory Medicine Case Reports, Vol.45, 101893, 2023.
(Tokushima University Institutional Repository: 119403,   DOI: 10.1016/j.rmcr.2023.101893,   PubMed: 37485237)
3. Seiya Ichihara, Hirokazu Ogino, Hiroto Yoneda, Keiko Haji, Kozo Kagawa, Kojin Murakami, Masato Mima, Yu Aoi, Atsushi Mitsuhashi, Yuki Tsukazaki, Yohei Yabuki, Ryohiko Ozaki, Seidai Satou, Hiroshi Nokihara and Yasuhiko Nishioka :
Immune checkpoint inhibitor-related pneumonitis with atypical radiologic features in a patient with anti-aminoacyl-tRNA synthetase antibody.,
Respiratory Medicine Case Reports, Vol.41, 101797, 2023.
(Tokushima University Institutional Repository: 119054,   DOI: 10.1016/j.rmcr.2022.101797,   PubMed: 36583061)
4. Makoto Tobiume, Atsushi Mitsuhashi, Atsuro Saijo, Hirokazu Ogino, Tania Afroj, Hirohisa Ogawa, Hisatsugu Goto, Seidai Satou, Akane Abe, Keiko Haji, Ryohiko Ozaki, Hiromitsu Takizawa and Yasuhiko Nishioka :
Analysis of the chemotactic factors for tumor-infiltrating fibrocytes and their prognostic significances in lung cancer.,
Oncology Letters, Vol.24, No.5, 417, 2022.
(DOI: 10.3892/ol.2022.13537,   PubMed: 36245829)
5. Kenji Otsuka, Hiroshi Nokihara, Atsushi Mitsuhashi, Ryohiko Ozaki, Yohei Yabuki, Hiroto Yoneda, Hirokazu Ogino and Yasuhiko Nishioka :
Efficacy and safety of second-line chemotherapy for patients with advanced non-small cell lung cancer complicated by interstitial lung disease.,
Thoracic Cancer, Vol.13, No.21, 2978-2984, 2022.
(Tokushima University Institutional Repository: 118615,   DOI: 10.1111/1759-7714.14645,   PubMed: 36106507)
6. Hiroshi Nokihara, Hirokazu Ogino, Atsushi Mitsuhashi, Kensuke Kondo, Ei Ogawa, Ryohiko Ozaki, Yohei Yabuki, Hiroto Yoneda, Kenji Otsuka and Yasuhiko Nishioka :
Efficacy of osimertinib in epidermal growth factor receptor-mutated non-small-cell lung cancer patients with pleural effusion.,
BMC Cancer, Vol.22, No.1, 2022.
(Tokushima University Institutional Repository: 117282,   DOI: 10.1186/s12885-022-09701-2,   PubMed: 35650550)
7. Masahiro Sako, Hiroshi Nokihara, Kensuke Kondo, Atsushi Mitsuhashi, Ryohiko Ozaki, Yohei Yabuki, Akane Abe, Hiroto Yoneda, Hirokazu Ogino, Kenji Otsuka, Hisanori Uehara and Yasuhiko Nishioka :
A case of pulmonary pleomorphic carcinoma with preexisting interstitial pneumonia successfully treated with pembrolizumab.,
Thoracic Cancer, Vol.13, No.1, 129-132, 2021.
(Tokushima University Institutional Repository: 117393,   DOI: 10.1111/1759-7714.14243,   PubMed: 34859591)
8. Hiroto Yoneda, Hiroshi Nokihara, Atsushi Mitsuhashi, Ryohiko Ozaki, Yohei Yabuki, Hirokazu Ogino, Kenji Otsuka and Yasuhiko Nishioka :
Correlation between immune-related adverse events and therapeutic effects of nivolumab in patients with malignant pleural mesothelioma.,
BMC Pulmonary Medicine, Vol.21, No.1, 2021.
(Tokushima University Institutional Repository: 117283,   DOI: 10.1186/s12890-021-01746-6,   PubMed: 34781910)

Proceeding of International Conference:

1. Yabuki Yohei, Kenji Otsuka, Hirokazu Ogino, Takeuchi Eiji, Haku Takashi, Takanori Kanematsu, Nishimura Naoki, Yuko Toyoda, Masaki Hanibuchi, Atsushi Mitsuhashi, Tsukazaki Yuki, Ryohiko Ozaki, Hiroto Yoneda, Hiroshi Nokihara and Yasuhiko Nishioka :
A multicenter, open-label, phase II trial of pemetrexed plus bevacizumab in elderly patients with advanced or recurrent non-squamous non-small cell lung cancer,
APSR 2022, Seoul, Nov. 2022.
2. Ryohiko Ozaki, Hiroshi Nokihara, Yabuki Youhei, Atsushi Mitsuhashi, Hiroto Yoneda, Kenji Otsuka, Hirokazu Ogino and Yasuhiko Nishioka :
The examination of the second-line chemotherapy in SCLC patients with interstitial lung disease,
ERS International Congress 2022, Barcelona, Sep. 2022.
3. Ryohiko Ozaki, Hiroshi Nokihara, Atsushi Mitsuhashi, Kondou Kensuke, YABUKI Yohhei, Hiroto Yoneda, Hirokazu Ogino, Kenji Otsuka and Yasuhiko Nishioka :
The clinical efficacy and safety of the second-line chemotherapy in extensive-disease small cell lung cancer patients with interstitial lung disease,
APSR 2021, Kyoto and online, Nov. 2021.
4. Hiroto Yoneda, Hiroshi Nokihara, Atsushi Mitsuhashi, Ryohiko Ozaki, YABUKI Yohhei, Hirokazu Ogino, Kenji Otsuka and Yasuhiko Nishioka :
Association of immune-related adverse events with therapeutic response to Nivolumab in patients with malignant pleural mesothelioma,
APSR 2021, Kyoto and online, Nov. 2021.

Proceeding of Domestic Conference:

1. Noriko Bando, Hiroki Bandoh, Keiko Haji, 美馬 正人, Asami Fukuya, Nobuhito Naito, Ryohiko Ozaki, Hirokazu Ogino, Seidai Satou, Hiroshi Kawano, Satoshi Sakaguchi, Masaki Hanibuchi and Yasuhiko Nishioka :
当科における重症喘息に対する生物学的製剤の治療効果の検討,
第268回徳島医学会学術集会, Mar. 2024.
2. Yuki Tsukazaki, Hirokazu Ogino, Yoshio Okano, Soji Kakiuchi, Shoko Harada, Yugo Matumura, Seiya Ichihara, Takeshi Imakura, Ryohiko Ozaki, Ei Ogawa, Yutaka Morita, Atsushi Mitsuhashi, Yohei Yabuki, Hiroto Yoneda, Masaki Hanibuchi, Yuko Toyoda, Kayoko Hase, Eiji Takeuchi, Takashi Haku and Yasuhiko Nishioka :
The impacts of G-CSF on the therapeutic efficacy of chemo-immunotherapy for extensive-stage small cell lung cancer.,
2024 the Japanese Society of Medical Oncology Annual Meeting (JSMO2024), Feb. 2024.
3. Hirokazu Ogino, Nguyen Na Thi, Hiroyuki Kozai, Atsushi Mitsuhashi, Yuki Tsukazaki, Yohei Yabuki, Ryohiko Ozaki, Hiroshi Nokihara, Masaki Hanibuchi and Yasuhiko Nishioka :
Fluoropyrimidine has a potential to be an immunologically optimal partner ofimmunotherapy for thoracic malignancies.,
2024 the Japanese Society of Medical Oncology Annual Meeting (JSMO2024), Feb. 2024.
4. Ryoko Suzue, Hiroki Bandoh, Keiko Haji, Ryohiko Ozaki, Hiroto Yoneda, Hirokazu Ogino, Seidai Satou, Masaki Hanibuchi and Yasuhiko Nishioka :
抗横紋筋抗体陽性の重症irAE筋炎・心筋炎に対して早期の集学的治療が奏効した肺扁平上皮癌の1例,
第69回日本呼吸器学会中国・四国地方会, Dec. 2023.
5. Yuki Tsukazaki, Makoto Tobiume, Atsushi Mitsuhashi, Ryohiko Ozaki, Yohei Yabuki, Hiroto Yoneda, Hirokazu Ogino, Masaki Hanibuchi, Hirohisa Ogawa, Hiromitsu Takizawa and Yasuhiko Nishioka :
非小細胞肺癌症例における腫瘍浸潤線維細胞の走化因子と疾患予後との関連性についての解析,
第64回日本肺癌学会学術集会, Nov. 2023.
6. Hirokazu Ogino, Hiroyuki Kozai, Atsushi Mitsuhashi, Yuki Tsukazaki, Yohei Yabuki, Ryohiko Ozaki, Hiroto Yoneda, Masaki Hanibuchi, Hiroshi Nokihara and Yasuhiko Nishioka :
フッ化ピリミジンは胸部腫瘍の免疫原性細胞死を誘導し免疫チェックポイント阻害薬の至適併用薬となり得る,
第64回日本肺癌学会学術集会, Nov. 2023.
7. Ryohiko Ozaki, Hiroshi Nokihara, Yuki Tsukazaki, Yohei Yabuki, Atsushi Mitsuhashi, Hiroto Yoneda, Hirokazu Ogino and Yasuhiko Nishioka :
進展型小細胞肺癌において2次治療が受けられない患者の臨床的背景の検討,
第64回日本肺癌学会学術集会, Nov. 2023.
8. Ryohiko Ozaki, 小川 瑛, Hiroshi Nokihara, Atsushi Mitsuhashi, Yohei Yabuki, Hiroto Yoneda, Hirokazu Ogino and Yasuhiko Nishioka :
ALK融合遺伝子陽性非小細胞肺癌の効果予測因子に関する検討,
第61回日本癌治療学会学術集会, Oct. 2023.
9. Yohei Yabuki, Atsushi Mitsuhashi, Hirokazu Ogino, Na Thi Nguyen, Hiroto Yoneda, Ryohiko Ozaki, Yuki Tsukazaki, Masaki Hanibuchi, Hiroshi Nokihara and Yasuhiko Nishioka :
HIF1A 阻害による腫瘍細胞由来 CXCL10/11 制御を介した抗 PDL1 抗体への耐性克服,
第82回日本癌学会学術総会, Sep. 2023.
10. Yuki Tsukazaki, Atsushi Mitsuhashi, Ryohiko Ozaki, Yohhei Yabuki, Hiroto Yoneda, Hirokazu Ogino and Yasuhiko Nishioka :
肺癌における腫瘍浸潤線維細胞の走化因子とその疾患予後に及ぼす影響についての解析,
第27回日本がん分子標的治療学会学術集会, Jun. 2023.
11. Yohhei Yabuki, Atsushi Mitsuhashi, Na Thi Nguyen, Hirokazu Ogino, Hiroto Yoneda, Ryohiko Ozaki and Yasuhiko Nishioka :
IFN-g 反応性ケモカイン産生制御機序の解明と新規複合がん免疫療法への応用,
第27回日本がん分子標的治療学会学術集会, Jun. 2023.
12. Hirokazu Ogino, Ryohiko Ozaki, Kenji Otsuka, Atsushi Mitsuhashi, Yuki Tsukazaki, Yohhei Yabuki, Hiroto Yoneda, Hiroshi Nokihara and Yasuhiko Nishioka :
間質性肺炎を合併する進行期肺癌に対する二次化学療法の有効性および安全性に関する検討,
第120回日本内科学会講演会, Apr. 2023.
13. Tsukazaki Yuki, Ogawa Ei, Hiroshi Nokihara, Atsushi Mitsuhashi, Kondo Kensuke, Yabuki Youhei, Ryohiko Ozaki, Hiroto Yoneda, Hirokazu Ogino and Yasuhiko Nishioka :
The prognostic factors for the efficacy of anaplastic lymphoma kinase inhibitors in non-small cell lung cancer,
2023 the Japanese Society of Medical Oncology Annual Meeting, Mar. 2023.
14. Ryohiko Ozaki, Hiroshi Nokihara, Tukazaki Yuki, Yabuki Yohei, Atsushi Mitsuhashi, Hiroto Yoneda, Hirokazu Ogino and Yasuhiko Nishioka :
Clinical factors of not receiving second-line chemotherapy in ED-SCLC patients,
2023 the Japanese Society of Medical Oncology Annual Meeting, Mar. 2023.
15. Hirokazu Ogino, Kondo Kensuke, Atsushi Mitsuhashi, Tsukazaki Yuki, Ryohiko Ozaki, Yabuki Yohei, Hiroto Yoneda, Hiroshi Nokihara and Yasuhiko Nishioka :
The novel prognostic system for the efficacy of immune checkpoint inhibitors in non-small cell lung cancer,
2023 the Japanese Society of Medical Oncology Annual Meeting, Mar. 2023.
16. 森 彩花, Keiko Haji, Yu Aoi, Kenya Miyamoto, Kojin Murakami, Yuki Tsukazaki, Hiroki Bandoh, Ryohiko Ozaki, Kozo Kagawa, Hirokazu Ogino, Seidai Satou, Masaki Hanibuchi and Yasuhiko Nishioka :
免疫チェックポイント阻害薬使用後に肺胞出血をきたした1例,
第31回日本呼吸器内視鏡学会中国四国支部会, Dec. 2022.
17. 中西 颯斗, Keiko Haji, 松村 有悟, Atsushi Mitsuhashi, 小川 瑛, Takeshi Imakura, 美馬 正人, Ryohiko Ozaki, Hiroto Yoneda, Hirokazu Ogino, Satoshi Sakaguchi, Seidai Satou, Masaki Hanibuchi and Yasuhiko Nishioka :
同時に異なる3つの組織型を認めた多発性肺癌の1例,
第67回日本呼吸器学会中国・四国地方会, Dec. 2022.
18. 小川 瑛, Hiroshi Nokihara, Atsushi Mitsuhashi, 近藤 健介, Yuki Tsukazaki, Yohhei Yabuki, Ryohiko Ozaki, Hiroto Yoneda, Hirokazu Ogino and Yasuhiko Nishioka :
ALK融合遺伝子陽性非小細胞肺癌の効果予測因子に関する検討,
第63回日本肺癌学会学術集会, Dec. 2022.
19. Hiroshi Nokihara, Hirokazu Ogino, Atsushi Mitsuhashi, 近藤 健介, 小川 瑛, Ryohiko Ozaki, Yohhei Yabuki, Hiroto Yoneda and Yasuhiko Nishioka :
胸水を伴うEGFR遺伝子変異陽性非小細胞肺がんに対するオシメルチニブの有効性の検討,
第63回日本肺癌学会学術集会, Dec. 2022.
20. Ryohiko Ozaki, Hiroshi Nokihara, Yuki Tsukazaki, Yohhei Yabuki, Atsushi Mitsuhashi, Hiroto Yoneda, Hirokazu Ogino and Yasuhiko Nishioka :
間質性肺炎合併進展型小細胞肺癌における2次化学療法の有効性および安全性について,
第60回日本癌治療学会学術集会, Oct. 2022.
21. 松村 有悟, Keiko Haji, 美馬 正人, Yohhei Yabuki, Kenji Otsuka, Hiroto Yoneda, Hiroshi Nokihara, Hirokazu Ogino, Ryohiko Ozaki, 塚崎 佑貴, Seidai Satou, Masaki Hanibuchi and Yasuhiko Nishioka :
小細胞肺癌への形質転換を認めたEGFR遺伝子変異陽性肺腺癌の3例,
第60回日本肺癌学会中国・四国支部学術集会, Jul. 2022.
22. Hiroto Yoneda, Atsushi Mitsuhashi, Hirokazu Ogino, Ryohiko Ozaki, Yohhei Yabuki, Hiroshi Nokihara, Shinji Abe, 加藤 幸成 and Yasuhiko Nishioka :
悪性胸膜中皮腫に対する抗ポドプラニン抗体および抗CTLA-4抗体による複合がん免疫療法の検討,
第26回日本がん分子標的治療学会学術集会, Jun. 2022.
23. Kojin Murakami, 原田 紗希, Takeshi Imakura, Atsushi Mitsuhashi, 小川 瑛, TSUKAZAKI Yuki, Ryohiko Ozaki, YABUKI Yohhei, Kozo Kagawa, Hiroto Yoneda, Akane Abe, Hirokazu Ogino, Kazuya Koyama, Seidai Satou, Satoshi Sakaguchi and Yasuhiko Nishioka :
抗GM-CSF抗体測定が早期診断に有用であった自己免疫性肺胞蛋白症の一例,
第45回日本呼吸器内視鏡学会学術集会, May 2022.
24. Takeshi Imakura, Seidai Satou, 原田 紗希, Atsushi Mitsuhashi, 小川 瑛, Kojin Murakami, Yuki Tsukazaki, Ryohiko Ozaki, Yohhei Yabuki, Kozo Kagawa, Hiroto Yoneda, Akane Abe, Hirokazu Ogino, Satoshi Sakaguchi and Yasuhiko Nishioka :
肺門部・縦隔リンパ節腫大に対してEBUS-TBNAを実施し子宮頸癌再発と診断した1例,
第45回日本呼吸器内視鏡学会学術集会, May 2022.
25. 美馬 正人, Seidai Satou, 原田 紗希, 鈴江 涼子, Yuya Yamashita, Ryohiko Ozaki, Keiko Haji, Nobuhito Naito, Hiroshi Kawano, Hiroshi Nokihara and Yasuhiko Nishioka :
抗ARS抗体陽性間質性肺疾患の胸部画像所見の検討,
第62回日本呼吸器学会学術講演会, Apr. 2022.
26. Ryohiko Ozaki, Hiroshi Nokihara, YABUKI Yohhei, Atsushi Mitsuhashi, Hiroto Yoneda, Kenji Otsuka, Hirokazu Ogino and Yasuhiko Nishioka :
Second-line chemotherapy for extensive-disease small cell lung cancer with interstitial lung disease,
第19回日本臨床腫瘍学会学術集会, Feb. 2022.
27. 村上 尚哉, YABUKI Yohhei, Ryohiko Ozaki, Kozo Kagawa, Hirokazu Ogino, Seidai Satou, Hiroshi Kawano, Hiroshi Nokihara and Yasuhiko Nishioka :
Sitafloxacinが奏効した肺Mycobacterium abscessus subsp. massiliense 症の1例,
第72回日本結核・非結核性抗酸菌症学会中国四国支部会, Dec. 2021.
28. 原田 祥子, YABUKI Yohhei, 美馬 正人, Ryohiko Ozaki, Kozo Kagawa, Hirokazu Ogino, Seidai Satou, Hiroshi Kawano, Hiroshi Nokihara and Yasuhiko Nishioka :
非結核性抗酸菌症との鑑別を要し，amikacin + minocyclineが奏効した肺ノカルジア,
第65回日本呼吸器学会中国・四国地方会, Dec. 2021.
29. Ryohiko Ozaki, Hiroshi Nokihara, Atsushi Mitsuhashi, 近藤 健介, YABUKI Yohhei, Hiroto Yoneda, Hirokazu Ogino, Kenji Otsuka and Yasuhiko Nishioka :
間質性肺炎合併小細胞肺癌に対する二次化学療法の有効性及び安全性の検討,
第62回日本肺癌学会学術集会, Nov. 2021.
30. Hiroto Yoneda, Hiroshi Nokihara, Atsushi Mitsuhashi, Ryohiko Ozaki, YABUKI Yohhei, Hirokazu Ogino, Kenji Otsuka and Yasuhiko Nishioka :
悪性胸膜中皮腫患者におけるニボルマブの免疫関連有害事象と治療効果の相関性,
第59回日本癌治療学会学術集会, Oct. 2021.
31. Kenji Otsuka, Atsushi Mitsuhashi, Ryohiko Ozaki, YABUKI Yohhei, Hiroto Yoneda, Hirokazu Ogino, Hiroshi Nokihara, 竹内 栄治, 杉浦 八十生, 知花 賢治, 田村 厚久, 安宅 信二 and Yasuhiko Nishioka :
進展型小細胞肺癌における予後規定因子,
第59回日本癌治療学会学術集会, Oct. 2021.
32. 市原 聖也, YABUKI Yohhei, Ryohiko Ozaki, 近藤 健介, Hiroto Yoneda, Kenji Otsuka, Asami Fukuya, 高丸 利加子, 原田 祥子, Hirokazu Ogino, Seidai Satou, Hiroshi Nokihara and Yasuhiko Nishioka :
AtezolizumabのImmune-Related Adverse Eventによる急性腎障害を認めた非小細胞肺癌の1例,
第59回日本肺癌学会中国・四国支部学術集会, Aug. 2021.
33. 高丸 利加子, Nobuhito Naito, 原田 紗希, YAMASHITA Yuya, Ryohiko Ozaki, Naoki Takahashi, Seidai Satou, Hiroshi Kawano, Hiroshi Nokihara and Yasuhiko Nishioka :
当科における全身性エリテマトーデスに対するベリムマブの使用経験,
第124回日本内科学会四国地方会, May 2021.
34. Hiroyuki Kozai, Atsushi Mitsuhashi, Ryohiko Ozaki, Hiroto Yoneda, Kenji Otsuka, Hiroshi Nokihara and Yasuhiko Nishioka :
免疫原性細胞死を誘導する細胞傷害性抗癌剤についての検討,
第61回日本呼吸器学会学術講演会, Apr. 2021.

Grants-in-Aid for Scientific Research (KAKEN Grants Database @ NII.ac.jp)