Tokushima University / Educator and Researcher Directory --- Ikeda, Ayano

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Tokushima University ⟩ Graduate School of Biomedical Sciences ⟩ 医学域 ⟩ Medical Nutrition ⟩ Medical Nutrition ⟩ Department of Clinical Nutrition and Food Management ⟩
Tokushima University ⟩ Graduate School of Medical Nutrition ⟩ Medical Nutrition ⟩
Tokushima University ⟩ Faculty of Medicine ⟩ School of Medical Nutrition ⟩ Course of Clinical and Applied Nutrition ⟩ Department of Clinical Nutrition and Food Management ⟩

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Research

Personal Web Page

https://researchmap.jp/ikeda.ayano (researchmap)

Field of Study

○	Life sciences [Nutrition and health science]
○	Life sciences [Cardiology]

Subject of Study

Book / Paper

(See https://researchmap.jp/ikeda.ayano (researchmap) for Published Book / Papers / Presentations.)

Book:

1.	Hirokazu Ohminami, Masaki Takikawa, Ayano Kitamura, Mina Matsubara and Yutaka Taketani : Accurate measurement of energy metabolism and its usefulness for dialysis patients, 日本メディカルセンター, Apr. 2023. (Link to Publication Site) ● Publication site (DOI): 10.19020/cd.0000002513 (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1390014337396806144 ● Search Scopus @ Elsevier (DOI): 10.19020/cd.0000002513 (DOI: 10.19020/cd.0000002513, CiNii: 1390014337396806144)

Academic Paper (Judged Full Paper):

1.	Masaki Takikawa, Hirokazu Ohminami, Takayuki Uchida, Ayano Kitamura, Yuichiro Adachi, Yuki Mori, Kohta Ohnishi, Masashi Masuda, Hisami Yamanaka-Okumura and Yutaka Taketani : Dietary combination of sucrose and linoleic acid increases intramyocellular lipid and impairs muscle strength in female Zucker diabetic fatty rats., Journal of Clinical Biochemistry and Nutrition, 76, 3, 271-279, 2025. (Summary) Sarcopenic obesity is associated with metabolic disorders and physical limitations. Intramyocellular lipid (IMCL) accumulation is a critical factor affecting muscle strength, independent of muscle mass, in obesity. While diet plays an important role in regulating IMCL, the effects of specific dietary combinations remain poorly understood. This study examined the effects of different combinations of dietary carbohydrates and fats on skeletal muscle quality and function in obese rats. Female Zucker diabetic fatty rats were fed diets containing either sucrose or palatinose combined with either oleic or linoleic acid for 12 weeks. Body and muscle weights, IMCL content, and grip strength were measured. C2C12 myotubes were treated in vitro with varying concentrations of glucose or insulin, along with fatty acids (oleic acid or linoleic acid), to mimic the exposure of each diet. The diet combining sucrose and linoleic acid (SL) significantly increased IMCL accumulation in the extensor digitorum longus (EDL) muscle and reduced grip strength. A negative correlation was observed between IMCL and grip strength. Cluster of differentiation 36 (CD36) protein levels tended to increase in the EDL of the SL diet-fed group. In vitro experiments demonstrated that high glucose levels combined with linoleic acid increased IMCL and CD36 expression. In conclusion, diets high in sucrose and linoleic acid exacerbate IMCL accumulation and reduce muscle strength in obese rats through hyperglycemia-induced interaction. (Link to Publication Site) ● Publication site (DOI): 10.3164/jcbn.24-229 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 40510391 ● Summary page in Scopus @ Elsevier: 2-s2.0-105004057833 (DOI: 10.3164/jcbn.24-229, PubMed: 40510391, Elsevier: Scopus)
2.	Yosuke Okumura, Kotaro Abe, Shoko Sakai, Yuki Kamei, Yuki Mori, Yuichiro Adachi, Masaki Takikawa, Ayano Kitamura, Hirokazu Ohminami, Kohta Ohnishi, Masashi Masuda, Taiho Kambe, Hironori Yamamoto and Yutaka Taketani : Elevated luminal inorganic phosphate suppresses intestinal Zn absorption in 5/6 nephrectomized rats, American Journal of Physiology, Renal Physiology, 326, 3, F411-F419, 2024. (Summary) binder might be useful for the treatment of hypozincemia and hyperphosphatemia. (Keyword) Humans / Rats / Animals / Phosphates / hyperphosphatemia / Zinc / Renal Insufficiency, Chronic / Nephrectomy / Intestinal Absorption (Tokushima University Institutional Repository) ● Metadata: 2012041 (Link to Publication Site) ● Publication site (DOI): 10.1152/ajprenal.00310.2023 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 38234299 ● CiNii @ National Institute of Informatics (CRID): 1910585658881299840 ● Summary page in Scopus @ Elsevier: 2-s2.0-85185726165 (Tokushima University Institutional Repository: 2012041, DOI: 10.1152/ajprenal.00310.2023, PubMed: 38234299, CiNii: 1910585658881299840, Elsevier: Scopus)

Proceeding of Domestic Conference:

1.	山本真由, Hirokazu Ohminami, 和田七海, Ayano Kitamura, 大島あいり, 源平結愛, 木元真, 長野愛実, Masashi Masuda and Yutaka Taketani : 心不全の進行度別にみた高脂肪食摂取の効果, 第29回日本病態栄養学会年次学術集会, Feb. 2026.
2.	Ayano Kitamura, Hirokazu Ohminami, Masashi Masuda, Takayuki Ise, Shusuke Yagi, Masataka Sata and Yutaka Taketani : 有酸素運動が不全心筋のBCAA代謝に及ぼす影響, 第31回日本心臓リハビリテーション学会学術集会, Jul. 2025.
3.	山本真由, Hirokazu Ohminami, 和田七海, Ayano Kitamura, 大島あいり, 源平結愛, 木元真, 長野愛実, 増田真志 and Yutaka Taketani : 心不全の進行度別に見た高脂肪食摂取の効果, 第29回日本病態栄養学会年次学術集会, Jan. 2025.
4.	和田七海, Hirokazu Ohminami, Ayano Kitamura, 松原未奈, 竹ノ内咲音, Masashi Masuda and Yutaka Taketani : 概日リズムからみた不全心筋のエネルギー代謝障害, 第28回日本病態栄養学会年次学術集会, Jan. 2025.
5.	竹ノ内咲音, Hirokazu Ohminami, 和田七海, Ayano Kitamura, 松原未奈, Masashi Masuda and Yutaka Taketani : 心不全マウスにおける肝糖新生能の検討, 第28回日本病態栄養学会年次学術集会, Jan. 2025.
6.	Ayano Kitamura, Hirokazu Ohminami, Masashi Masuda and Yutaka Taketani : 高脂肪食が心不全マウスの骨格筋脂質代謝に及ぼす影響, 第9回日本栄養改善学会四国支部学術総会, Jun. 2024.
7.	Hirokazu Ohminami, Ayano Kitamura, Masashi Masuda, Takayuki Ise, Shusuke Yagi, Masataka Sata and Yutaka Taketani : 心不全マウスに対する高脂肪食と運動の併用効果，優秀演題アワードセッショ, 日本心臓リハビリテーション学会第7回四国支部地方会, Mar. 2024.
8.	Hirokazu Ohminami, Ayano Kitamura, MINA Matsubara, Masashi Masuda, Takayuki Ise, Shusuke Yagi, Masataka Sata and Yutaka Taketani : 動物モデルから探る心リハ栄養としての糖・脂質組成の意義, 第29回日本心臓リハビリテーション学会学術集会, Jul. 2023.
9.	Hirokazu Ohminami, Ayano Kitamura, 松原未奈, Masashi Masuda, Takayuki Ise, Shusuke Yagi, Masataka Sata and Yutaka Taketani : 動物モデルから探る病期別心リハ栄養の可能性, 第12回日本リハビリテーション栄養学会学術集会, Jan. 2023.
10.	Ayano Kitamura, Hirokazu Ohminami, 松原未奈, Masashi Masuda, Takayuki Ise, Shusuke Yagi, Masataka Sata and Yutaka Taketani : 高脂肪食が心不全マウスの骨格筋エネルギー代謝に及ぼす影響, 第26回日本病態栄養学会年次学術集会, Jan. 2023.
11.	Ayano Kitamura, Hirokazu Ohminami, Masashi Masuda, Hisami Okumura, Takayuki Ise, Shusuke Yagi, Daiju Fukuda, Hirotsugu Yamada, Masataka Sata and Yutaka Taketani : 運動介入中の脂質摂取の違いが心不全マウスの病態に及ぼす影響, 第28回日本心臓リハビリテーション学会学術集会, Jun. 2022.
12.	Ayano Kitamura, Hirokazu Ohminami, Masashi Masuda, Hisami Okumura, Takayuki Ise, Shusuke Yagi, Daiju Fukuda, Hirotsugu Yamada, Masataka Sata and Yutaka Taketani : 運動および栄養介入が心不全マウスの病態に及ぼす影響, 日本心臓リハビリテーション学会第 5 回四国支部地方会, Jan. 2022.
13.	Masaki Takikawa, Hirokazu Ohminami, Ayano Kitamura, Minami Kunihiro, Mutsumi Kondoh, Mina Matsubara, Masashi Masuda, Hisami Okumura and Yutaka Taketani : スクロースとリノール酸の組み合せは筋肉脂肪を増加させる, 第 54 回日本栄養・食糧学会中国・四国支部大会/第7 回日本栄養改善学会四国支部学術総会合同大会, Oct. 2021.
14.	Hirokazu Ohminami, Ayano Kitamura, Miku Yamaguchi, Masaki Takikawa, Kohta Ohnishi, Masashi Masuda, Hisami Okumura, Takayuki Ise, Shusuke Yagi, Daiju Fukuda, Hirotsugu Yamada, Masataka Sata and Yutaka Taketani : 心不全マウスを用いた心リハ評価系の確立, 第27回日本心臓リハビテーション学会, Jun. 2021.

Grants-in-Aid for Scientific Research (KAKEN Grants Database @ NII.ac.jp)

リンによる心筋代謝リモデリングを介した新規心不全制御機構の解明 (Project/Area Number: 26K25489 )
Search by Researcher Number (41039078)