Tokushima University / Educator and Researcher Directory --- Nakamoto, Akiko

Personal Web Page

https://researchmap.jp/a-nakamoto (researchmap)

Field of Study

○	Life sciences [Nutrition and health science]
○	Life sciences [Immunology]

Subject of Study

Book / Paper

Book:

1.	Akiko Nakamoto : 管理栄養士養成のための栄養学教育モデル・コア・カリキュラム準拠公衆栄養学 2024年版公衆栄養活動の実践のための理論と展開, 医歯薬出版株式会社, Feb. 2024.
2.	Tohru Sakai, 郡俊之, Mariko Nakamoto and Akiko Nakamoto : 公衆栄養学第7版, Kodansha, Tokyo, Jan. 2023.
3.	Akiko Nakamoto : 感染防御と栄養, 株式会社薬事日報社, Jul. 2022.
4.	Akiko Nakamoto : 栄養科学シリーズNEXT 公衆栄養学第6版, 株式会社講談社サイエンティフィク, Jan. 2022.
5.	Akiko Nakamoto : 管理栄養士養成のための栄養学教育モデル・コア・カリキュラム準拠第10巻「公衆栄養学」 2022年版, 医歯薬出版株式会社, 2022.
6.	Akiko Nakamoto : 管理栄養士養成のための栄養学教育モデル・コア・カリキュラム準拠第10巻公衆栄養学 2021年度版公衆栄養活動の実践のための理論と展開, 医歯薬出版株式会社, Mar. 2021.
7.	Akiko Nakamoto : 栄養科学シリーズNEXT 公衆栄養学第6版, 株式会社講談社サイエンティフィク, Feb. 2019.
8.	Akiko Nakamoto : 管理栄養士講座改訂感染と生体防御, KENPAKUSHA, Tokyo, Sep. 2018.

Academic Paper (Judged Full Paper):

1.	Jing Wang, Yuki Hashimoto, Miki Hiemori-Kondo, Akiko Nakamoto, Tohru Sakai, Wenxiu Ye and Naomi Abe-Kanoh : Resveratrol and piceid enhance efferocytosis by increasing the secretion of MFG-E8 in human THP-1 macrophages., Bioscience, Biotechnology, and Biochemistry, 1-12, 2024. (Summary) The process of apoptotic cell clearance by phagocytes, known as efferocytosis, plays an essential role in maintaining homeostasis. Defects in efferocytosis can lead to inflammatory diseases such as atherosclerosis and autoimmune disorders. Therefore, the maintenance and promotion of efferocytosis are considered crucial for preventing these diseases. In this study, we observed that resveratrol, a representative functional food ingredient, and its glycoside, piceid, promoted efferocytosis in both human THP-1 macrophages differentiated with phorbol 12-myristate 13-acetate and peritoneal macrophages from thioglycolate-elicited mice. Resveratrol and piceid significantly increased mRNA expression and protein secretion of MFG-E8 in THP-1 macrophages. Furthermore, the activation of efferocytosis and the increment in MFG-E8 protein secretion caused by resveratrol or piceid treatment were canceled by MFG-E8 knockdown in THP-1 macrophages. In conclusion, we have demonstrated for the first time that resveratrol and piceid promote efferocytosis through the upregulation of MFG-E8 excretion in human THP-1 macrophages. (Link to Publication Site) ● Publication site (DOI): 10.1093/bbb/zbae079 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 38830798 ● Search Scopus @ Elsevier (PMID): 38830798 ● Search Scopus @ Elsevier (DOI): 10.1093/bbb/zbae079 (DOI: 10.1093/bbb/zbae079, PubMed: 38830798)
2.	Mariko Nakamoto, Koki Torami, Thuy Thi Bui, Ayumi Tojyo, Kana Yamada, Akiko Nakamoto, Akiko Hata, Nanako Aki, Yosuke Shikama, Yukiko Bandou, Takako Ichihara, Takako Minagawa, Ayako Tamura, Yumi Kuwamura, Makoto Funaki and Tohru Sakai : Associations between dietary diversity and high sensitive C-reactive protein among Japanese workers: findings of a cross-sectional and longitudinal study., European Journal of Nutrition, 2024. (Summary) These findings suggest that, in male Japanese workers, higher dietary diversity might be important for maintaining a low inflammatory status. (Tokushima University Institutional Repository) ● Metadata: 119532 (Link to Publication Site) ● Publication site (DOI): 10.1007/s00394-024-03389-9 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 38780630 ● Search Scopus @ Elsevier (PMID): 38780630 ● Search Scopus @ Elsevier (DOI): 10.1007/s00394-024-03389-9 (Tokushima University Institutional Repository: 119532, DOI: 10.1007/s00394-024-03389-9, PubMed: 38780630)
3.	TANAKA Yuko, Akiko Nakamoto, Haruka Ohhashi, Mariko Nakamoto and Tohru Sakai : Flavonoids, nobiletin, heptamethoxyflavone, and genistein enhance antigen-presenting cell function in vitro, Exploration of Immunology, Vol.4, 333-340, 2024.
4.	Thuy Thi Bui, Mariko Nakamoto, Kana Yamada, Akiko Nakamoto, Akiko Hata, Nanako Aki, Yosuke Shikama, Yukiko Bandou, Takako Ichihara, Takako Minagawa, Ayako Tamura, Yumi Kuwamura, Makoto Funaki and Tohru Sakai : Associations between dietary diversity and dyslipidemia among Japanese workers: cross-sectional study and longitudinal study findings., European Journal of Nutrition, 2024. (Summary) The results of cross-sectional analysis in this study suggest that the higher diversity of diet might reduce the presence of dyslipidemia in men and the results of longitudinal analysis suggest that a moderate DDS might reduce the risk of dyslipidemia in women. Further studies are needed since the results of cross-sectional and longitudinal analyses in this study were inconsistent. (Tokushima University Institutional Repository) ● Metadata: 119533 (Link to Publication Site) ● Publication site (DOI): 10.1007/s00394-024-03403-0 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 38703224 ● Search Scopus @ Elsevier (PMID): 38703224 ● Search Scopus @ Elsevier (DOI): 10.1007/s00394-024-03403-0 (Tokushima University Institutional Repository: 119533, DOI: 10.1007/s00394-024-03403-0, PubMed: 38703224)
5.	Mariko Nakamoto, Koki Torami, Miku Kanmura, Mai Yoshida, Akiko Nakamoto and Tohru Sakai : Changes in higher-level functional capacity during the COVID-19 pandemic among older adults living in Japan., The Journal of Medical Investigation : JMI, Vol.71, No.1.2, 66-74, 2024. (Summary) The findings suggest an association of the COVID-19 pandemic with a decrease in higher-level functional capacity, especially in Social Role, among older adults living in Japan. J. Med. Invest. 71 : 66-74, February, 2024. (Keyword) Humans / COVID-19 / Female / Male / Aged / Japan / Aged, 80 and over / Retrospective Studies / Pandemics / Surveys and Questionnaires / lifestyle / Geriatric Assessment (Tokushima University Institutional Repository) ● Metadata: 119430 (Link to Publication Site) ● Publication site (DOI): 10.2152/jmi.71.66 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 38735727 ● Search Scopus @ Elsevier (PMID): 38735727 ● Search Scopus @ Elsevier (DOI): 10.2152/jmi.71.66 (Tokushima University Institutional Repository: 119430, DOI: 10.2152/jmi.71.66, PubMed: 38735727)
6.	Yuko Tanaka, Mako Yamamoto, Haruka Ohhashi, Akiko Nakamoto, Mariko Nakamoto and Tohru Sakai : The Soy Isoflavone Genistein Enhances IFN-γ-Induced PD-L1 Expression in B16F1 Melanoma Cells in Vitro, BPB Reports, Vol.7, No.1, 21-25, 2024. (Link to Publication Site) ● Publication site (DOI): 10.1248/bpbreports.7.1_21 (Link to Search Site for Scientific Articles) ● Search Scopus @ Elsevier (DOI): 10.1248/bpbreports.7.1_21 (DOI: 10.1248/bpbreports.7.1_21)
7.	Mako Yamamoto, Yuko Tanaka, Risako Takeda, Akiko Nakamoto, Mariko Nakamoto, Hideo Yagita and Tohru Sakai : Soy isoflavone genistein attenuates the efficacy of immune checkpoint therapy in C57BL/6 mice inoculated with B16F1 melanoma and a high PD-L1 expression level reflects tumor resistance., Journal of Clinical Biochemistry and Nutrition, Vol.74, No.1, 57-62, 2023. (Summary) cells and the concentrations of interferon-γ and tumor necrosis factor-α in tumor tissue were not different among the experimental groups. A significant difference was also not found in microbe composition. Interestingly, a high expression level of PD-ligand (L)1 closely reflected the outcome of therapy by genistein or anti-PD-1 antibody. The study showed that a combination of genistein treatment does not improve the effect of immune blockade therapy. It also showed that a high PD-L1 expression level in tumors is a good prediction maker for the outcome of tumor therapy. (Link to Publication Site) ● Publication site (DOI): 10.3164/jcbn.23-76 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 38292119 ● Search Scopus @ Elsevier (PMID): 38292119 ● Search Scopus @ Elsevier (DOI): 10.3164/jcbn.23-76 (DOI: 10.3164/jcbn.23-76, PubMed: 38292119)
8.	Akiko Nakamoto, Yuwa Hirabayashi, Chieri Anzaki, Mariko Nakamoto, Emi Shuto, Yoshitaka Nii and Tohru Sakai : Effects of polymethoxyflavonoids on T helper 17 cell differentiation in vitro and in vivo., The Journal of Medical Investigation : JMI, Vol.70, No.1.2, 166-170, 2023. (Tokushima University Institutional Repository) ● Metadata: 118348 (Link to Publication Site) ● Publication site (DOI): 10.2152/jmi.70.166 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 37164715 ● Search Scopus @ Elsevier (PMID): 37164715 ● Search Scopus @ Elsevier (DOI): 10.2152/jmi.70.166 (Tokushima University Institutional Repository: 118348, DOI: 10.2152/jmi.70.166, PubMed: 37164715)
9.	Akiko Nakamoto, Miho Goto, Hina Hasegawa, Chieri Anzaki, Mariko Nakamoto, Emi Shuto and Tohru Sakai : Essential Oil of Citrus sudachi Suppresses T Cell Activation Both In Vitro and In Vivo., Journal of Nutritional Science and Vitaminology, Vol.68, No.6, 513-520, 2022. (Link to Publication Site) ● Publication site (DOI): 10.3177/jnsv.68.513 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 36596549 ● Search Scopus @ Elsevier (PMID): 36596549 ● Search Scopus @ Elsevier (DOI): 10.3177/jnsv.68.513 (DOI: 10.3177/jnsv.68.513, PubMed: 36596549)
10.	Mariko Nakamoto, Miku Kanmura, Mai Yoshida, Yukiko Tanaka, Satomi Ono, Yuki Iwasaki, Akiko Nakamoto and Tohru Sakai : Validity of dietary diversity assessed using short-form questionnaire among older Japanese community dwellers., The Journal of Medical Investigation : JMI, Vol.69, No.1.2, 31-37, 2022. (Summary) The validity of dietary variety score (DVS) using a short-form questionnaire has not been investigated using dietary diversity based on a quantitative distribution of consumed foods in older Japanese. We examined the association between DVS and objective dietary diversity using a Quantitative Index for Dietary Diversity (QUANTIDD) based on the quantitative distribution of foods consumed by older Japanese community dwellers. The subjects were 65 older Japanese community dwellers aged 60?79 years. We used two kinds of scores for assessment of dietary diversity. At first, dietary diversity was determined using DVS calculated from answers to a questionnaire about frequencies of intake of 10 food groups. Second, dietary intake was assessed using a 3-day dietary record with photographs, and dietary diversity was determined using QUANTIDD. The relationships between DVS and QUANTIDD were assessed using partial correlation coefficients controlling for confounders. The correlation coefficient between DVS and QUANTIDD was moderate (r=0.212-0.458). After controlling for confounders, those correlation coefficient between DVS and QUANTIDD remained moderate. The findings suggest that there was a moderate relationship between DVS and QUANTIDD, and DVS using a short-form questionnaire may be useful for assessing dietary diversity in older Japanese community dwellers. J. Med. Invest. 69 : 31-37, February, 2022. (Keyword) Aged / Diet / Eating / Food / Humans / Japan / Surveys and Questionnaires (Tokushima University Institutional Repository) ● Metadata: 117008 (Link to Publication Site) ● Publication site (DOI): 10.2152/jmi.69.31 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 35466143 ● Search Scopus @ Elsevier (PMID): 35466143 ● Search Scopus @ Elsevier (DOI): 10.2152/jmi.69.31 (Tokushima University Institutional Repository: 117008, DOI: 10.2152/jmi.69.31, PubMed: 35466143)
11.	Mariko Nakamoto, Miku Kanmura, Mai Yoshida, Kana Yamada, Akiko Nakamoto and Tohru Sakai : Dietary diversity and food choice motives during the COVID-19 pandemic among older Japanese: An Internet Panel Survey., Asia Pacific Journal of Clinical Nutrition, Vol.31, No.3, 433-440, 2022. (Summary) The findings suggest that the COVID-19 pandemic was associated with an increase in some food choice motives and a decrease in the frequency of eating out among elderly female Japanese. (Keyword) Aged / COVID-19 / Diet / Feeding Behavior / Female / Humans / Internet / Japan / Male / Pandemics / Retrospective Studies / Surveys and Questionnaires (Tokushima University Institutional Repository) ● Metadata: 118468 (Link to Publication Site) ● Publication site (DOI): 10.6133/apjcn.202209_31(3).0011 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 36173215 ● Search Scopus @ Elsevier (PMID): 36173215 ● Search Scopus @ Elsevier (DOI): 10.6133/apjcn.202209_31(3).0011 (Tokushima University Institutional Repository: 118468, DOI: 10.6133/apjcn.202209_31(3).0011, PubMed: 36173215)
12.	Akiko Nakamoto, Hirabayashi Yuwa, Anzaki Chieri, Mariko Nakamoto, Emi Shuto and Tohru Sakai : Nobiletin suppresses the development of experimental autoimmune encephalomyelitis mediated by modulation of T helper 17 cell differentiation, Journal of Clinical Biochemistry and Nutrition, Vol.69, No.2, 145-150, 2021. (Summary) Multiple sclerosis is an organ-specific autoimmune disease that targets the myelin antigen in the central nervous system. Nobiletin is a dietary polymethoxylated flavonoid found in citrus fruits. In this study, we investigated how nobiletin affects the disease state and immune responses to myelin oligodendrocyte glycoprotein in experimental autoimmune encephalomyelitis mice. Nobiletin was administered orally from 14 days before immunization until the end of the experiment, and clinical scores were determined. The production levels of interleukin-17A and interferon-γ were measured in a culture supernatant of splenocytes stimulated with myelin oligodendrocyte glycoprotein. In addition, flow cytometric analysis was performed to examine the effect of nobiletin on T cell differentiation . Admin-istration of nobiletin significantly decreased the clinical score and interleukin-17A production in splenocytes. Furthermore, analysis showed that nobiletin significantly suppressed Th17 cell differentiation and interleukin-17A production in a dose-dependent manner. The results suggest that nobiletin attenuates experimental autoimmune encephalomyelitis severity through modulation of Th17 cell differentiation. (Tokushima University Institutional Repository) ● Metadata: 116141 (Link to Publication Site) ● Publication site (DOI): 10.3164/JCBN.20-178 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 34616106 ● Summary page in Scopus @ Elsevier: 2-s2.0-85114706108 (Tokushima University Institutional Repository: 116141, DOI: 10.3164/JCBN.20-178, PubMed: 34616106, Elsevier: Scopus)
13.	Akiko Nakamoto, Risako Takeda, Yuwa Hirabayashi, Mariko Nakamoto, Emi Shuto and Tohru Sakai : Citrus Polymethoxyflavonoids, Nobiletin, Heptamethoxyflavone and Natsudaidain, Suppress T Cell Activation In Vitro and In Vivo, BPB Reports, Vol.3, No.4, 138-141, 2020. (Link to Publication Site) ● Publication site (DOI): 10.1248/bpbreports.3.4_138 (Link to Search Site for Scientific Articles) ● Search Scopus @ Elsevier (DOI): 10.1248/bpbreports.3.4_138 (DOI: 10.1248/bpbreports.3.4_138)
14.	Mariko Nakamoto, Yuna Yun, Mariko Omine, Sarasa Mori, Emi Shuto, Akiko Nakamoto, Akiko Hata, Nanako Aki, Yosuke Shikama, Yukiko Bandou, Takako Ichihara, Takako Minagawa, Ayako Tamura, Yumi Kuwamura, Makoto Funaki and Tohru Sakai : Dietary diversity and characteristics of lifestyle and awareness of health in Japanese workers:a cross-sectional study., The Journal of Medical Investigation : JMI, Vol.67, No.3.4, 255-264, 2020. (Summary) The aim of this study was to clarify the characteristics of lifestyle and health awareness according to dietary diversity in a Japanese worksite population. The participants were 1,312 men and women aged 20 to 63 years who were living in Tokushima Prefecture, Japan during the period 2012-2013. We obtained anthropometric data and information on lifestyle characteristics using a self-administered questionnaire. Dietary intake was assessed using a food frequency questionnaire, and dietary diversity was determined using the Quantitative Index for Dietary Diversity (QUANTIDD). The characteristics of lifestyle and health awareness according to quartiles of the QUANTIDD score were assessed using the chi-square test and a general linear model. The higher the QUANTIDD score was, the larger were the proportions of participants who knew the appropriate amount of dietary intake and participants who referred to nutritional component information when choosing and/or buying food. Among participants with higher QUANTIDD scores, the proportion of participants who considered their current diet was good was high in women, whereas the proportion of participants who wanted to improve their diet in the future was high in men. Those results indicate that higher dietary diversity was related to better characteristics of lifestyle and awareness of health. J. Med. Invest. 67 : 255-264, August, 2020. (Tokushima University Institutional Repository) ● Metadata: 115420 (Link to Publication Site) ● Publication site (DOI): 10.2152/jmi.67.255 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 33148898 ● Search Scopus @ Elsevier (PMID): 33148898 ● Search Scopus @ Elsevier (DOI): 10.2152/jmi.67.255 (Tokushima University Institutional Repository: 115420, DOI: 10.2152/jmi.67.255, PubMed: 33148898)
15.	Mami Mitani, Yuki Minatogawa, Akiko Nakamoto, Mariko Nakamoto, Emi Shuto, Yoshitaka Nii and Tohru Sakai : Sudachitin, polymethoxyflavone from Citrus sudachi, enhances antigen-specific cellular and humoral immune responses in BALB/c mice., Journal of Clinical Biochemistry and Nutrition, Vol.64, No.2, 158-163, 2019. (Link to Publication Site) ● Publication site (DOI): 10.3164/jcbn.18-70 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 30936628 ● Summary page in Scopus @ Elsevier: 2-s2.0-85064387091 (DOI: 10.3164/jcbn.18-70, PubMed: 30936628, Elsevier: Scopus)
16.	Mariko Nakamoto, Mariko Omine, Yuna Yun, Emi Shuto, Akiko Nakamoto, Akiko Hata, Nanako Aki, Yosuke Shikama, Yukiko Bandou, Takako Ichihara, Takako Minagawa, Ayako Tamura, Yumi Kuwamura, Makoto Funaki and Tohru Sakai : Associations of dietary diversity with allergic diseases in Japanese workers: a cross-sectional study., Asia Pacific Journal of Clinical Nutrition, Vol.28, No.4, 857-869, 2019. (Summary) The aim of this study was to determine the associations of dietary diversity with prevalences of allergic diseases. The participants were 1,317 men and women aged 20 to 63 years who were living in Tokushima Prefecture, Japan during the period 2012-2013. We obtained anthropometric data and information on lifestyle characteristics and current medical histories of allergic diseases using a self-administered questionnaire. Dietary intake was assessed using a food frequency questionnaire, and dietary diversity was determined using the Quantitative Index for Dietary Diversity (QUANTIDD). The ORs and 95% CIs for each of the allergic diseases with a 1 standard deviation (SD) increase in the QUANTIDD score were estimated, controlling for age, family history of allergic diseases, education, smoking, drinking, physical activity, energy intake and BMI. Higher dietary diversity showed significant inverse dose-response relationships with allergic diseases and allergic rhinitis in women. Multivariate-adjusted ORs (95% CI) for allergic diseases and allergic rhinitis with 1 SD increase in the QUANTIDD score were 0.77 (95% CI: 0.60-0.98, p=0.037) and 0.69 (95% CI: 0.53-0.90, p=0.007), respectively, in women. There were no significant associations between dietary diversity and allergic diseases in men. The results indicate that there is an inverse association between higher dietary diversity and allergic rhinitis in Japanese female workers. (Keyword) Adult / Asthma / Cross-Sectional Studies / Dermatitis, Atopic / Diet / Female / Food / Humans / Japan / Male / Middle Aged / Rhinitis, Allergic / Risk Factors / Young Adult (Link to Publication Site) ● Publication site (DOI): 10.6133/apjcn.201912_28(4).0023 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 31826384 ● Summary page in Scopus @ Elsevier: 2-s2.0-85076486533 (DOI: 10.6133/apjcn.201912_28(4).0023, PubMed: 31826384, Elsevier: Scopus)
17.	Mariko Nakamoto, Yukiko Tanaka, Satomi Ono, Akiko Nakamoto, Emi Shuto and Tohru Sakai : Associations of marital and parental status and family members living together with health-related behaviors in Japanese young workers : a cross-sectional study., The Journal of Medical Investigation : JMI, Vol.66, No.1-2, 141-147, 2019. (Summary) The aim of this study was to clarify the associations of family members living together with healthrelated behaviors in Japanese young workers. The participants were 300 men and women aged 20-39 years in 2015 who had a job. A web-based self-administered questionnaire on status of partnering and parenting, number of family members living together, dietary habits, drinking habit, smoking habit, self-rated health, employment status, working time and commuting time was conducted through Internet. Multiple logistic regression analysis and general linear models were used to assess the association of family members living together with healthrelated behaviors. The multivariate-adjusted odds ratio (95% confidence interval, p-value) for current drinking in unmarried participants living with their parents compared to unmarried participants living alone was 0.35 (0.13-0.93, p=0.036). The adjusted means of frequency of breakfast skipping and frequency of eating out showed a trend for inverse associations with the presence of a partner and children. However, those associations disappeared after adjustment for age of youngest child. The findings suggest that the presence of parents might affect drinking behavior and that age of youngest child living together might affect the frequency of breakfast skipping in young Japanese workers. J. Med. Invest. 66 : 141-147, February, 2019. (Keyword) epidemiology / nutrition (Tokushima University Institutional Repository) ● Metadata: 113409 (Link to Publication Site) ● Publication site (DOI): 10.2152/jmi.66.141 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 31064927 ● Search Scopus @ Elsevier (PMID): 31064927 ● Search Scopus @ Elsevier (DOI): 10.2152/jmi.66.141 (Tokushima University Institutional Repository: 113409, DOI: 10.2152/jmi.66.141, PubMed: 31064927)
18.	Akiko Nakamoto, Mami Mitani, Kana Urayama, Akari Maki, Mariko Nakamoto, Emi Shuto, Yoshitaka Nii and Tohru Sakai : Nobiletin Enhances Induction of Antigen-Specific Immune Responses in BALB/c Mice Immunized with Ovalbumin., Journal of Nutritional Science and Vitaminology, Vol.65, No.3, 278-282, 2019. (Link to Publication Site) ● Publication site (DOI): 10.3177/jnsv.65.278 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 31257269 ● Search Scopus @ Elsevier (PMID): 31257269 ● Search Scopus @ Elsevier (DOI): 10.3177/jnsv.65.278 (DOI: 10.3177/jnsv.65.278, PubMed: 31257269)
19.	Mariko Nakamoto, Emi Shuto, Akiko Nakamoto, Akiko Hata, Nanako Aki, Yosuke Shikama, Yukiko Bandou, Takako Ichihara, Takako Minagawa, Ayako Tamura, Yumi Kuwamura, Makoto Funaki and Tohru Sakai : Soy product and isoflavone intake associations with allergic diseases in Japanese workers: rhinitis, dermatitis and asthma., Asia Pacific Journal of Clinical Nutrition, Vol.27, No.6, 1277-1285, 2018. (Summary) The aim of this study was to determine the associations of intake of soy products and isoflavones with allergic diseases. We conducted a cross-sectional study in 1437 participants (aged 20-64 years) who were living in Tokushima Prefecture, Japan during the period 2010- 2011. We obtained anthropometric data and information on life style characteristics including dietary intake and current medical histories of allergic diseases using a structural self-administered questionnaire. Multiple logistic regression models were used to assess the associations of soy products and isoflavones with allergic diseases after controlling for age, family history of allergic diseases, smoking, drinking, physical activity, energy intake, BMI and dietary factors. Intake of soy products showed significant inverse dose-response relationships with allergic rhinitis. The third quartile for soy products had an adjusted OR of 0.56 (95% CI: 0.35-0.91) compared to the reference group (first quartile), though intake of soy products showed no dose-response relationship with atopic dermatitis. Intake of soy isoflavones showed a significant inverse dose-response relationship with atopic dermatitis, though the association between intake of soy isoflavones and atopic dermatitis was U-shaped after adjustments for potential confounders. On the other hand, the associations between intake of soy isoflavones and other allergic diseases were not significant. The results indicate that higher intake of soy products is associated with reduced risk of allergic rhinitis in Japanese workers. Furthermore, moderate intake amounts of soy products and soy isoflavones are associated with inverse risk of atopic dermatitis. (Keyword) epidemiology / nutrition (Link to Publication Site) ● Publication site (DOI): 10.6133/apjcn.201811_27(6).0015 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 30485927 ● Search Scopus @ Elsevier (PMID): 30485927 ● Search Scopus @ Elsevier (DOI): 10.6133/apjcn.201811_27(6).0015 (DOI: 10.6133/apjcn.201811_27(6).0015, PubMed: 30485927)
20.	Tohru Sakai, Miyuki Ohhata, Misaki Fujii, Sayaka Oda, Yasuna Kusaka, Miki Matsumoto, Akiko Nakamoto, Tomoyo Taki, Mariko Nakamoto and Emi Shuto : Brazilian Green Propolis Promotes Weight Loss and Reduces Fat Accumulation in C57BL/6 Mice Fed A High-Fat Diet, Biological & Pharmaceutical Bulletin, Vol.40, No.4, 391-395, 2017. (Summary) Propolis is a bee product with various biological properties. C57BL/6 mice were fed a high-fat diet and treated with propolis for 14 weeks. Body weight in mice treated with 2% propolis was less than that in control mice from 3 weeks after the start of treatment until 14 weeks except for the 7th week. Mice treated with propolis showed significantly lower epididymal fat weight and subcutaneous fat weight. Infiltration of epididymal fat by macrophages and T cells was reduced in the propolis group. Supplementation of propolis increased feces weight and fat content in feces, suggesting that mechanisms of weight reduction by propolis partly include a laxative effect and inhibition of fat absorption. (Keyword) propolis / weight / fat absorption (Link to Publication Site) ● Publication site (DOI): 10.1248/bpb.b16-00577 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 28381793 ● Summary page in Scopus @ Elsevier: 2-s2.0-85016978833 (DOI: 10.1248/bpb.b16-00577, PubMed: 28381793, Elsevier: Scopus)
21.	Tohru Sakai, Tomoyo Taki, Akiko Nakamoto, Shiho Tazaki, Mai Arakawa, Mariko Nakamoto, Rie Tsutsumi and Emi Shuto : Dietary ribonucleic Acid suppresses inflammation of adipose tissue and improves glucose intolerance that is mediated by immune cells in C57BL/6 mice fed a high-fat diet., Journal of Nutritional Science and Vitaminology, Vol.61, No.1, 73-78, 2015. (Summary) Recent evidence suggests that immune cells play an important role in differentiation of inflammatory macrophages in adipose tissue, which contributes to systemic chronic inflammation. Dietary ribonucleic acid (RNA) has been shown to modulate immune function. We hypothesized that RNA affects immune cell function in adipose tissue and then improves inflammatory response in adipose tissue. C57/BL6 mice and recombination activating gene-1 (RAG-1) knockout mice on a C57BL/6 mice background were fed a high-fat diet containing 1% RNA for 12 wk. An oral glucose tolerance test was performed. Supplementation of dietary RNA in C57BL/6 mice fed a high-fat diet resulted in a smaller area under the curve (AUC) after oral glucose administration than that for control mice. The mRNA expression levels of inflammation-related cytokines in adipose tissue and serum interleukin-6 levels were reduced by dietary RNA supplementation. Interestingly, reduction of the AUC value by RNA supplementation was abolished in T and B cell-deficient RAG-1 knockout mice. These results indicate that RNA improves inflammation in adipose tissue and reduces the AUC value following oral glucose administration in a T and B cell-dependent manner. (Link to Publication Site) ● Publication site (DOI): 10.3177/jnsv.61.73 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 25994141 ● Summary page in Scopus @ Elsevier: 2-s2.0-84929733065 (DOI: 10.3177/jnsv.61.73, PubMed: 25994141, Elsevier: Scopus)
22.	Akiko Nakamoto, Emi Shuto, Rie Tsutsumi, Mariko Nakamoto, Yoshitaka Nii and Tohru Sakai : Vitamin A Deficiency Impairs Induction of Oral Tolerance in Mice., Journal of Nutritional Science and Vitaminology, Vol.61, No.2, 147-153, 2015. (Summary) Oral tolerance is a phenomenon of induction of systemic unresponsiveness to antigens ingested by the oral route and loss of immune response. Studies have shown the importance of vitamin A in oral tolerance in vitro but not in an in vivo experimental model. Therefore, we carried out experiments to determine how vitamin A deficiency affects tolerance induction and the ability of mesenteric lymph node (MLN) CD11c(+) cells to induce regulatory T cells (Tregs). Immunological tolerance was induced by oral ovalbumin (OVA) administration in vitamin A-sufficient mice. OVA-specific antibody and cytokine production were significantly reduced. On the other hand, in vitamin A-deficient mice, both OVA-specific antibody and cytokine production were not suppressed by oral OVA administration. Regarding induction of Tregs, the conversion rate of Foxp3(+) cells from naïve CD4(+) cell by CD11c(+) cells was decreased in vitamin A-deficient mice. Our study indicates that vitamin A deficiency causes the breakdown of oral tolerance in vivo. (Link to Publication Site) ● Publication site (DOI): 10.3177/jnsv.61.147 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 26052145 ● Summary page in Scopus @ Elsevier: 2-s2.0-84930703907 (DOI: 10.3177/jnsv.61.147, PubMed: 26052145, Elsevier: Scopus)
23.	Tohru Sakai, Mariko Nakamoto, Akiko Nakamoto, Emi Shuto, 小林ゆき子, 土居幸雄 and 木戸康弘 : Academic Degrees and Teacher Competency Requirements in Dietitian and National Registered Dietitian Training Facilities, The Japanese Journal of Nutrition and Dietetics, Vol.72, No.5, 262-271, 2014. (Summary) Objective: To obtain personnel information of teaching staff in universities, colleges, and vocational schools with dietitian and/or registered dietitian programs, including number of teaching staff with a dietitian or registered dietitian license and the distribution of academic degrees. Competencies (e.g., education, research administration) required of staff for teaching the curriculum were also evaluated.Methods: A mail survey was conducted in February and March 2013 inquiring on number of teaching staff, number of teaching staff with a dietitian license or who were registered dietitians, and age and position of staff. In addition, staff competencies were evaluated for their importance in dietitian and registered dietitian training facilities.Results: The response rate was 66.1% (78 schools) and 68.5% (102 schools) for dietitian and registered dietitian training facilities, respectively. Most teachers were aged 30~49 in both dietitian and registered dietitian training facilities. In registered dietitian training facilities, 40% of teachers over age 30 had their Ph.D., and 39.5%, 75.9%, and 66.5% aged 20~29, 30~49, and 50~65 had a master's and/or doctoral degree, respectively. In dietitian training facilities, about 20% of teachers over age 30 had a Ph.D., and 28.4%, 47.4%, and 44.0% aged 20~29, 30~49, and 50~65 had a master's and/or doctoral degree, respectively. "Education" was considered the most important competency.Conclusion: We obtained basic information concerning age and education characteristics of teachers in dietitian and national registered dietitian training schools. Education was identified by facility directors as the most important competency. (Keyword) dietitian and national registered dietitian training facilities / teacher / degree / competency (Link to Publication Site) ● Publication site (DOI): 10.5264/eiyogakuzashi.72.262 (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1390001206547275776 ● Search Scopus @ Elsevier (DOI): 10.5264/eiyogakuzashi.72.262 (DOI: 10.5264/eiyogakuzashi.72.262, CiNii: 1390001206547275776)

Academic Paper (Unrefereed Paper):

1.	Kana Yamada, Mariko Nakamoto, Akiko Nakamoto, Akiko Hata, 安藝菜奈子, Yosuke Shikama, Yukiko Bandou, Takako Ichihara, Takako Minagawa, Ayako Tamura, Yumi Kuwamura, Makoto Funaki and Tohru Sakai : 日本人勤労者の大豆製品摂取行動がメタボリック症候群発症に与える影響の検証, Soy Protein Research, Japan, Vol.26, No.44, 200-209, 2023. (Keyword) soy products / metabolic syndrome / Japanese male workers / a longitudinal study (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1520301231228971136 (CiNii: 1520301231228971136)
2.	Shuhai Chen, Masaaki Nishi, Yuji Morine, Kouzou Yoshikawa, Takuya Tokunaga, Hideya Kashihara, Chie Takasu, Yuuma Wada, Toshiaki Yoshimoto, Akiko Nakamoto, Tohru Sakai and Mitsuo Shimada : Polymethoxylated flavone sudachitin is a safe anticancer adjuvant that targets glycolysis in cancer-associated fibroblasts., Oncology Letters, Vol.24, No.1, 236, 2022. (Summary) Sudachitin is a polymethoxylated flavone found in the peel of , a unique specialty citrus fruit in Tokushima Prefecture, Japan. Previous reports have demonstrated that sudachitin has anti-inflammatory and metabolic regulatory activities. However, to the best of our knowledge, no studies have explored whether sudachitin can act as an antitumor therapeutic agent by regulating metabolic functions in the tumor microenvironment. In the present study, cell proliferation and cytotoxicity assays were used to determine whether sudachitin inhibited the growth of liver cancer and pancreatic carcinoma, cholangiocarcinoma and colorectal cancer cells and to compare its toxicity against normal fibroblasts and induced cancer-associated fibroblasts (CAFs). Using lactate assays and reverse transcription-quantitative PCR, the effects of sudachitin on glycolysis in CAFs were investigated. The effects of CAFs on malignant tumor cells were evaluated using cell proliferation, wound healing and invasion assays. As result, sudachitin inhibited various types of tumor cells with different half-maximal inhibitory concentrations. Treatment with 50 µM sudachitin for 48 h suppressed tumor and CAFs proliferation but was not cytotoxic against normal fibroblasts. This dose also inhibited glycolysis in CAFs and, thus, diminished their pro-tumorigenic activities. Overall, the present study revealed that sudachitin has promise as a safe and widely available natural antitumor adjuvant. (Tokushima University Institutional Repository) ● Metadata: 118072 (Link to Publication Site) ● Publication site (DOI): 10.3892/ol.2022.13356 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 35720469 ● Search Scopus @ Elsevier (PMID): 35720469 ● Search Scopus @ Elsevier (DOI): 10.3892/ol.2022.13356 (Tokushima University Institutional Repository: 118072, DOI: 10.3892/ol.2022.13356, PubMed: 35720469)

Review, Commentary:

1.	Tohru Sakai, Akiko Nakamoto and 新居佳孝 : 徳島県特産のスダチ -果皮成分の機能性についてー, New Food Industry, Vol.60, No.9, 19-24, 2018.

Proceeding of Domestic Conference:

1.	KUNITOMI Haruki, Mariko Nakamoto, BUI Tei Teyui, TORAMI Koki, Akiko Nakamoto and Tohru Sakai : 若年女性の食品重量推定に食品に対する視覚的注意は影響するか:食行動試験データの2次分析, 第71回日本栄養改善学会学術総会, Sep. 2024.
2.	TORAMI Koki, Mariko Nakamoto, BUI Tei Teyui, Yui Furutani, KUNITOMI Haruki, Akiko Nakamoto and Tohru Sakai : 若年女性における空腹状態に起因する食選択行動の違いに食品注視時間が及ぼす影響, 第267回徳島医学会学術集会, Aug. 2024.
3.	Ayumi Tohjoh, Mariko Nakamoto, BUI Tei Teyui, TORAMI Koki, Akiko Nakamoto, Akiko Hata, 安藝菜奈子, Yosuke Shikama, Yukiko Bandou, Takako Ichihara, Takako Minagawa, Yumi Kuwamura, Makoto Funaki and Tohru Sakai : 徳島県勤労者における植物性食事と脂質代謝マーカーとの縦断的検討, 第269回徳島医学会学術集会(令和6年度夏期), Jul. 2024.
4.	KUNITOMI Haruki, Mariko Nakamoto, BUI Tei Teyui, TORAMI Koki, Akiko Nakamoto and Tohru Sakai : 栄養学専攻学生における食品重量推定精度に及ぼす影響の検討, 第9回日本栄養改善学会四国支部学術総会, Jun. 2024.
5.	Haruka Ohhashi, TANAKA Yuko, Akiko Nakamoto, Mariko Nakamoto and Tohru Sakai : ノビレチンによるT細胞活性化に伴うサイトカイン産生の制御機構, 第78回日本栄養・食糧学会大会, 276, May 2024.
6.	Akiko Nakamoto, ISHIBASHI Mei, Mariko Nakamoto and Tohru Sakai : 肥満誘導初期におけるノビレチンのマクロファージ分極制御作用, 第78回日本栄養・食糧学会大会, 274, May 2024.
7.	Mariko Nakamoto, Tsuzuri Nagashima, Yukiko Tanaka, Satomi Ono, Yuki Iwasaki, Akiko Nakamoto, 張姝, kaoriori Kinoshita, Kanae Furuya, Tomoko Imai, Rei Otsuka and Tohru Sakai : 地域在住高齢者における日本食品成分表に基づく主要な13食品群の摂取頻度を用いた食事バランススコアの検討, 第34回日本疫学会学術総会, Jan. 2024. (Keyword) 地域在住高齢者 / 日本食品成分表 / 食事バランススコア
8.	Akiko Nakamoto, Moyu Takeuchi, Mariko Nakamoto and Tohru Sakai : 給食施設における使用済み布巾の殺菌方法とその効果に関する検討, 第18回日本給食経営管理学会学術総会, Nov. 2023.
9.	Mariko Nakamoto, Akiko Nakamoto, Yuka Hasegawa and Tohru Sakai : 環境負荷に基づく食事の寄与食品群特性に関する検証, 第18回日本給食経営管理学会学術総会, Nov. 2023. (Keyword) 環境負荷 / 食事
10.	TORAMI Koki, Mariko Nakamoto, BUI Tei Teyui, Yui Furutani, KUNITOMI Haruki, Akiko Nakamoto and Tohru Sakai : 若年者における空腹状態に起因する食選択行動に及ぼす食品注視時間の影響, 第70回日本栄養改善学会学術総会, Sep. 2023.
11.	Koki Torami, Mariko Nakamoto, THUY THI BUI, Akiko Nakamoto and Tohru Sakai : 若年者の空腹状態による食選択行動に及ぼす潜在的要因の影響, 第8回日本栄養改善学会四国支部学術総会, May 2023.
12.	Ayumi Tohjoh, Mariko Nakamoto, Kana Yamada, Koki Torami, Akiko Nakamoto, Akiko Hata, 安藝菜奈子, Yosuke Shikama, Yukiko Bandou, Takako Ichihara, Takako Minagawa, Ayako Tamura, Yumi Kuwamura, Makoto Funaki and Tohru Sakai : 徳島県勤労者における食事摂取の多様性と炎症性マーカーとの横断的検討, 第8回日本栄養改善学会四国支部学術総会, May 2023.
13.	Tohru Sakai, YAMAMOTO Mako, Akiko Nakamoto and Mariko Nakamoto : ガン免疫チェックポイント療法に対する大豆イソフラボンの併用投与に関する研究, 第77回日本栄養・食糧学会大会, 295, May 2023.
14.	Akiko Nakamoto, Maki Hattori, Mariko Nakamoto and Tohru Sakai : 抗炎症機構に対するポリメトキシフラボノイドの作用, 第77回日本栄養・食糧学会大会, 295, May 2023.
15.	Mariko Nakamoto, Ayumi Tohjoh, Kana Yamada, Koki Torami, Akiko Nakamoto, Akiko Hata, 安藝菜奈子, Yosuke Shikama, Yukiko Bandou, Takako Ichihara, Takako Minagawa, Ayako Tamura, Yumi Kuwamura, Makoto Funaki and Tohru Sakai : 徳島県勤労者における食事摂取の多様性と炎症マーカーとの関連, Journal of Japanese Society of Nutrition and Food Science, 74, May 2023.
16.	Mariko Nakamoto, Yui Shimizu, Akiko Nakamoto and Tohru Sakai : 管理栄養士養成課程の学生立案献立における食事多様性の高い献立の特徴, 第17回日本給食経営管理学会学術総会, Nov. 2022.
17.	山本真子, Akiko Nakamoto, Mariko Nakamoto, 八木田秀雄 and Tohru Sakai : 大豆イソフラボンのガン免疫チェックポイント療法への応用, The Japanese Journal of Nutrition and Dietetics, Vol.80, No.5, 200, Sep. 2022.
18.	Akiko Nakamoto, 守田栞捺, Mariko Nakamoto and Tohru Sakai : ノビレチンのサイトカイン産生調節作用を介した抗肥満効果, The Japanese Journal of Nutrition and Dietetics, Vol.80, No.5, 195, Sep. 2022.
19.	Mariko Nakamoto, Akiko Nakamoto and Tohru Sakai : 管理栄養士養成課程の学生に対する給食経営管理実習が管理栄養士のコンピテンシーへ及ぼす影響, The Japanese Journal of Nutrition and Dietetics, Vol.80, No.5, 186, Sep. 2022. (Keyword) 給食経営管理 / 給食 / 教育効果 / コンピテンシー / 管理栄養士
20.	Kana Yamada, Mariko Nakamoto, Akiko Nakamoto, Akiko Hata, Nanako Aki, Yosuke Shikama, Yukiko Bandou, Takako Ichihara, Takako Minagawa, Ayako Tamura, Yumi Kuwamura, Makoto Funaki and Tohru Sakai : 徳島県勤労者のイソフラボン摂取量とメタボリックシンドローム構成因子との関連, The Japanese Journal of Nutrition and Dietetics, Vol.80, No.5, 207, Sep. 2022. (Keyword) epidemiology / 公衆栄養 / 栄養疫学
21.	Akiko Nakamoto, HIRABAYASHI Yuwa, Mariko Nakamoto and Tohru Sakai : 17型ヘルパーT細胞に対するポリメトキシフラボノイドの作用-In vitroおよびin vivo系での検討-, 第20回四国免疫フォーラム, Jun. 2022.
22.	Kana Yamada, Mariko Nakamoto, Akiko Nakamoto, Akiko Hata, 安藝菜奈子, Yosuke Shikama, Yukiko Bandou, Takako Ichihara, Takako Minagawa, Ayako Tamura, Yumi Kuwamura, Makoto Funaki and Tohru Sakai : 徳島県勤労者の大豆イソフラボン摂取量とメタボリックシンドロームとの関連, 第264回徳島医学会学術集会, 32, Feb. 2022.
23.	Kana Yamada, Mariko Nakamoto, Akiko Nakamoto, Akiko Hata, 安藝菜奈子, Yosuke Shikama, Yukiko Bandou, Takako Ichihara, Takako Minagawa, Ayako Tamura, Yumi Kuwamura, Makoto Funaki and Tohru Sakai : 徳島県勤労者のイソフラボン摂取量とメタボリックシンドロームとの関連, 第6回日本糖尿病・生活習慣病ヒューマンデータ学会年次学術集会, Dec. 2021.
24.	TAKEI Rie, Emi Shuto, Akiko Nakamoto, Mariko Nakamoto and Tohru Sakai : 大豆イソフラボンの癌間細胞に及ぼす影響, 第54回日本栄養・食糧学会中国四国支部大会・第7回日本栄養改善学会四国支部学術総会合同大会, Oct. 2021.
25.	Kana Yamada, Mariko Nakamoto, Miku Kammura, Mai Yoshida, Rino Uenosono, Akiko Nakamoto and Tohru Sakai : 新型コロナウイルス感染拡⼤による高齢者の食選択動機及び食生活への影響, 第54回日本栄養・食糧学会中四国支部大会・第7回日本栄養改善学会四国支部学術合同総会, Oct. 2021.
26.	Akiko Nakamoto, Mariko Nakamoto and Tohru Sakai : スダチ果皮由来精油成分が免疫細胞に及ぼす作用と抗原特異的免疫応答への影響, 第68回日本栄養改善学会学術総会, Vol.79, No.5, 107, Oct. 2021.
27.	Mariko Nakamoto, Miku Kanmura, Mai Yoshida, Rino Uenosono, Kana Yamada, Akiko Nakamoto and Tohru Sakai : 新型コロナウイルス感染拡大に伴う初回緊急事態宣言前後での高齢者の食選択動機及び食品摂取多様性の変化, 第68回日本栄養改善学会学術総会, Vol.79, No.5, 187, Oct. 2021. (Keyword) epidemiology / 食選択動機 / 食生活 / 高齢者
28.	HIRABAYASHI Yuwa, Akiko Nakamoto, ANZAKI Chieri, Mariko Nakamoto, Emi Shuto and Tohru Sakai : T細胞分化に与えるポリメトキシフラボノイドの影響, 第75回日本栄養・食糧学会大会, 27, Jul. 2021.
29.	HIRABAYASHI Yuwa, Akiko Nakamoto, ANZAKI Chieri, Mariko Nakamoto, Emi Shuto and Tohru Sakai : 実験的自己免疫性脳脊髄炎(EAE)マウスに対するノビレチンの作用, 第53回日本栄養・食糧学会中国・四国支部大会, 13, Oct. 2020.
30.	Mariko Nakamoto, Satomi Ono, Yukiko Tanaka, Akiko Nakamoto, Emi Shuto and Tohru Sakai : 徳島県の子育て世代におけるワークライフバランスと食行動の関係, 第67回日本栄養改善学会学術総会, Vol.78, No.5, Sep. 2020.
31.	Akiko Nakamoto, ANZAKI Chieri, HIRABAYASHI Yuwa, Mariko Nakamoto, Emi Shuto and Tohru Sakai : マクロファージに対するポリメトキシフラボンの作用-敗血症モデルマウスを用いた検討-, 第67回日本栄養改善学会学術総会, Vol.78, No.5, 67, Sep. 2020.
32.	Akiko Nakamoto, HIRABAYASHI Yuwa, ANZAKI Chieri, Mariko Nakamoto, Emi Shuto and Tohru Sakai : ノビレチンによる実験的自己免疫性脳脊髄炎(EAE)におけるT細胞機能への影響, 第74回日本栄養・食糧学会大会, 205, Apr. 2020.
33.	Mariko Nakamoto, Mariko Ohmine, Yuna Yun, Emi Shuto, Akiko Nakamoto, Akiko Hata, Nanako Aki, Yosuke Shikama, Yukiko Bandou, Takako Ichihara, Takako Minagawa, Ayako Tamura, Yumi Kuwamura, Makoto Funaki and Tohru Sakai : Associations of dietary diversity with allergic diseases in Japanese workers: a cross-sectional study, Journal of Shikoku Public Health Society, Vol.65, No.1, 32, Feb. 2020. (Keyword) epidemiology / nutrition / allergy / Japan
34.	Akiko Nakamoto, Kana Urayama, Chieri Anzaki, Yuwa Hirabayashi, Mariko Nakamoto, Emi Shuto and Tohru Sakai : ポリメトキシフラボンの免疫細胞に対する機能評価 -マクロファージおよび肥満細胞での解析-, 第66回日本栄養改善学会学術総会, Sep. 2019.
35.	Kana Urayama, Akiko Nakamoto, Chieri Anzaki, Yuwa Hirabayashi, Mariko Nakamoto, Emi Shuto and Tohru Sakai : 免疫細胞に対するスダチ果皮フラボノイドの作用に関する研究-肥満細胞およびマクロファージにおける検討-, 第259回徳島医学会学術集会, Aug. 2019.
36.	Akiko Nakamoto, Emi Shuto, Mariko Nakamoto and Tohru Sakai : スダチ果皮に含まれるスダチチンのin vitroにおける機能評価 -マクロファージおよび肥満細胞での解析-, 第73回日本栄養・食糧学会大会, May 2019.
37.	Emi Shuto, Mariko Nakamoto, Akiko Nakamoto and Tohru Sakai : エクオールの前駆脂肪細胞3T3-L1に対する作用, 第73回日本栄養・食糧学会大会, May 2019.
38.	Kana Urayama, Akiko Nakamoto, Chieri Anzaki, Yuwa Hirabayashi, Mariko Nakamoto, Emi Shuto and Tohru Sakai : スダチ果皮フラボノイドの免疫細胞に対する作用に関する研究―肥満細胞およびマクロファージに対する作用―, 第6回日本栄養改善学会四国支部学術総会, Apr. 2019.
39.	Sho Hatayama, Takaaki Shimohata, Junko Kido, Yuna Kanda, Aya Tentaku, Shiho Fukushima, Mutsumi Nakahashi, Akiko Nakamoto, Emi Shuto, Takashi Uebanso, Kazuaki Mawatari and Akira Takahashi : Campylobacter jejuni汚染調理器具に対するUVA-LED照射殺菌の有効性について, 第39回日本食品微生物学会学術総会, Sep. 2018.
40.	Emi Shuto, Mariko Nakamoto, Akiko Nakamoto and Tohru Sakai : 食餌誘導性肥満マウスにおけるエクオールの作用, 第65回日本栄養改善学会学術総会, Sep. 2018.
41.	Akiko Nakamoto, Mariko Nakamoto, Emi Shuto and Tohru Sakai : スダチチンおよびデメトキシスダチチンによる免疫調節作用, 第65回日本栄養改善学会学術総会, Sep. 2018.
42.	Akiko Nakamoto, Mariko Nakamoto, Emi Shuto and Tohru Sakai : デメトキシスダチチンの免疫調節作用, 第5回日本栄養改善学会四国支部学術総会, Jun. 2018.
43.	Emi Shuto, Mayuka Kunimatsu, Akiko Nakamoto, Mariko Nakamoto and Tohru Sakai : 食餌誘導性肥満マウスにおけるエクオールの作用, 第72回日本栄養・食糧学会大会, May 2018.
44.	Akiko Nakamoto, Mariko Nakamoto, Emi Shuto and Tohru Sakai : デメトキシスダチチンによる免疫調節作用, 第72回日本栄養・食糧学会大会, May 2018.

Et cetera, Workshop:

1.	Sho Hatayama, Takaaki Shimohata, Junko Kido, Yuna Kanda, Aya Tentaku, Shiho Fukushima, Mutsumi Nakahashi, Akiko Nakamoto, Emi Shuto, Takashi Uebanso, Kazuaki Mawatari and Akira Takahashi : UVA-LED照射による調理器具汚染Campylobacter jejuniの殺菌効果について, 第11回日本カンピロバクター研究会総会, Dec. 2018.

Report:

1.	Mariko Nakamoto, Sarasa Mori, Emi Shuto, Akiko Nakamoto, Akiko Hata, Nanako Aki, Yosuke Shikama, Yukiko Bandou, Takako Ichihara, Takako Minagawa, Ayako Tamura, Yumi Kuwamura, Makoto Funaki and Tohru Sakai : Soy and Isoflavone Intake and Lifestyle and Health Awareness in Japanese Workers, SOY PROTEIN RESEARCH, Japan, Vol.24, 154-161, Jul. 2022.
2.	Mariko Nakamoto, Sarasa Mori, Akimitsu Ohkohji, Emi Shuto, Akiko Nakamoto, Akiko Hata, Nanako Aki, Yosuke Shikama, Yukiko Bandou, Takako Ichihara, Takako Minagawa, Ayako Tamura, Yumi Kuwamura, Makoto Funaki and Tohru Sakai : 大豆製品・大豆含有成分摂取と推定腎機能との関係を探る臨床疫学研究, Soy protein research, Vol.23, 182-191, 2020.

Grants-in-Aid for Scientific Research (KAKEN Grants Database @ NII.ac.jp)

フラボノイドのM2マクロファージ誘導機構を基盤とした慢性炎症疾患克服戦略 (Project/Area Number: 22K17778 )
Function of dietary polymethoxylated flavonoid on metabolism and immune function. (Project/Area Number: 19K11768 )
Prevention of metabolic syndrome by immunomodulatory action of soy isoflavone and elucidation of mechanism (Project/Area Number: 18K17967 )
Search by Researcher Number (90803536)

Assistant Professor : Nakamoto, Akiko

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Grants-in-Aid for Scientific Research (KAKEN Grants Database @ NII.ac.jp)