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Tokushima University ⟩ Graduate School of Biomedical Sciences ⟩ 医学域 ⟩ 先端医学教育研究プロジェクト ⟩
Tokushima University ⟩ Graduate School of Biomedical Sciences ⟩ 医学域 ⟩ Medical Science ⟩ Internal Medicine ⟩ Department of Nephrology ⟩
Tokushima University ⟩ University Hospital ⟩ Clinical Division ⟩ Department of Internal Medicine ⟩ Nephrology ⟩
Tokushima University ⟩ Faculty of Medicine ⟩ School of Medicine ⟩ Course of Biological Medicine ⟩ Nephrology ⟩
Tokushima University ⟩ Graduate School of Medicine ⟩ Medicine ⟩ Course of Biological Medicine ⟩ 		(Files for researchmap) [PDF manual] [Auto-propagate to researchmap]

Research

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Field of Study

○ Life sciences [Nephrology]

Subject of Study

Book / Paper

Academic Paper (Judged Full Paper):

1. Kazuhiro Hasegawa, Masanori Tamaki, Yusuke Sakamaki and Shu Wakino :
Deficiency Causes Mitoribosome Excess in Diabetic Nephropathy Mediated by Transcriptional Repressor HIC1.,
International Journal of Molecular Sciences, Vol.25, No.12, 2024.
(Tokushima University Institutional Repository: 119529,   DOI: 10.3390/ijms25126384,   PubMed: 38928090)
2. Kazuhiro Hasegawa, Masanori Tamaki, Eriko Shibata, Taizo Inagaki, Masanori Minato, Sumiyo Yamaguchi, Ikuko Shimizu, Shinji Miyakami, Miho Tada and Shu Wakino :
Ability of NAD and Sirt1 to epigenetically suppress albuminuria.,
Clinical and Experimental Nephrology, Vol.28, No.7, 599-607, 2024.
(Tokushima University Institutional Repository: 119528,   DOI: 10.1007/s10157-024-02502-w,   PubMed: 38587753)
3. Kazuhiro Hasegawa, Yusuke Sakamaki, Masanori Tamaki and Shu Wakino :
PCK1 Protects against Mitoribosomal Defects in Diabetic Nephropathy in Mouse Models.,
Journal of the American Society of Nephrology, Vol.34, No.8, 1343-1365, 2023.
(DOI: 10.1681/ASN.0000000000000156,   PubMed: 37199399)

Review, Commentary:

1. Kazuhiro Hasegawa, Masanori Tamaki, Eriko Shibata, Masanori Minato, Taizo Inagaki, 清水 郁子, 山口 純代, 宮上 慎司, 多田 美穂 and Shu Wakino :
特集 糖尿病性腎症研究の最前線 糖尿病性腎症の発症機序 糖尿病性腎症におけるミトコンドリアの役割,
Kidney and Dialysis, Vol.96, No.2, 159-164, Feb. 2024.
(DOI: 10.24479/kd.0000001187,   CiNii: 1390299528381041664)
2. Shu Wakino, Kazuhiro Hasegawa, Masanori Tamaki and Eriko Shibata :
特集 血液透析患者の血圧を再考する 5.透析患者の至適血圧-腹膜透析も含む,
The Japanese Journal of Clinical Dialysis, Vol.40, No.2, 155-163, Feb. 2024.
(DOI: 10.19020/cd.0000002887,   CiNii: 1390862168254226944)
3. Shu Wakino, Kazuhiro Hasegawa and Masanori Tamaki :
近位尿細管から見た糖尿病性腎臓病と肥満関連腎症,
Cardioangiology, Vol.93, No.2, 182-189, Feb. 2023.
(CiNii: 1520013962704009344)
4. Masanori Tamaki, Kazuhiro Hasegawa and Shu Wakino :
【急性腎障害(AKI)】AKIの病態とその対応 手術とAKI,
Kidney and Dialysis, Vol.94, No.1, 83-86, Jan. 2023.
(DOI: 10.24479/kd.0000000586,   CiNii: 1390016195131521024)
5. Kazuhiro Hasegawa and Shu Wakino :
【ポドサイトパチー】糖尿病性腎症におけるポドサイト傷害の見える化へ迫る最新論文,
Nephrology, Vol.15, No.6, 659-664, Jun. 2022.
(CiNii: 1520011108762623872)
6. Kazuhiro Hasegawa, Masanori Tamaki, 坂巻 裕介 and Shu Wakino :
ミトコンドリアとSIRT1/NMNと腎臓病,
Nephrology, Vol.15, No.5, 551-557, May 2022.
(CiNii: 1520292395539278336)

Proceeding of Domestic Conference:

1. Shu Wakino, 柴田 理恵子, Kazuhiro Hasegawa, Masanori Tamaki, Masanori Minato, Taizo Inagaki, 宮上 慎司, 多田 美穂 and Ichiro Hashimoto :
皮膚虚血・潰瘍病変患者における血中亜鉛濃度の意義,
第53回徳島透析療法研究会, Dec. 2023.
2. Shu Wakino and Kazuhiro Hasegawa :
教育講演 糖尿病性腎臓病の治療の進歩,
日本内科学会雑誌, Vol.112, No.9, 1680-1689, Sep. 2023.
(CiNii: 1520016184419352832)
3. Shu Wakino, Eriko Shibata, Masanori Minato, Ikuko Shimizu and Kazuhiro Hasegawa :
皮膚潰瘍病変患者における血中亜鉛濃度の意義,
Journal of Japanese Society for Dialysis Therapy, Vol.56, No.Suppl.1, 566, May 2023.
4. Shu Wakino, Kazuhiro Hasegawa and Masanori Tamaki :
AKD(acute kidney disease and disorders)を考える 透析導入阻止のためのAKD治療戦略,
Japanese Journal of Nephrology, Vol.65, No.3, 231, May 2023.
5. Kazuhiro Hasegawa, Masanori Tamaki and Shu Wakino :
心血管内分泌の新知見 尿細管糸球体連関とDKD,
Folia endocrinologica Japonica, Vol.99, No.1, 171, May 2023.
6. Masanori Minato, Ikuko Shimizu, Masanori Tamaki, Kazuhiro Hasegawa and Shu Wakino :
長時間のAPDにより至適透析を得た重度の精神発達遅滞を有する一例,
Journal of Japanese Society for Dialysis Therapy, Vol.56, No.Suppl.1, 563, 2023.
7. Kazuhiro Hasegawa, Masanori Tamaki and Shu Wakino :
時間空間的ネットワークで考えるDKDの基礎研究 尿細管糸球体クロストークとDKD,
Japanese Journal of Nephrology, Vol.64, No.6-W, 696, Oct. 2022.
8. Masanori Tamaki, 宮上 慎司, Ikuko Shimizu, 山口 純代, Masanori Minato, Sayo Ueda, Eriko Shibata, Kazuhiro Hasegawa and Shu Wakino :
ロキサデュスタット投与後に奇異性脳塞栓を発症した1例,
Japanese Journal of Nephrology, Vol.64, No.6-W, 719, Oct. 2022.
9. 宮上 慎司, Masanori Tamaki, Ikuko Shimizu, 山口 純代, Masanori Minato, Sayo Ueda, Eriko Shibata, Kazuhiro Hasegawa and Shu Wakino :
コロナウィルスワクチン後発症した悪性腎硬化症の一例,
Japanese Journal of Nephrology, Vol.64, No.6-W, 719, Oct. 2022.
10. Kazuhiro Hasegawa, Masanori Tamaki, 坂巻 裕介 and Shu Wakino :
腎臓病治療に対する新たな切り口 DMミトコンドリア機能改善薬やNADがDKDのみならず腎臓病への切り口となる可能性,
Japanese Journal of Nephrology, Vol.64, No.3, 189, May 2022.
11. Shu Wakino, Kazuhiro Hasegawa and 伊藤 裕 :
DKDに立ち向かう-これまでの100年とこれからの未来- DKD基礎研究の歩みと先端医療,
Japanese Journal of Nephrology, Vol.64, No.3, 189, May 2022.
12. Kazuhiro Hasegawa, Masanori Tamaki, 坂巻 裕介 and Shu Wakino :
NMN消費酵素Nmnatのポドサイト発現調節はE-boxへのepigenetic制御が担う,
Japanese Journal of Nephrology, Vol.64, No.3, 228, May 2022.
13. Masanori Tamaki, 宮上 慎司, Ikuko Shimizu, 山口 純代, Masanori Minato, Sayo Ueda, Eriko Shibata, Motoyuki Tamaki, Motoyuki Tamaki, Kazuhiro Hasegawa, Kojiro Nagai and Shu Wakino :
ESAからロキサデュスタットへ切り替えた保存期CKD症例の解析,
Japanese Journal of Nephrology, Vol.64, No.3, 257, May 2022.
14. Kazuhiro Hasegawa, Masanori Tamaki, 坂巻 裕介 and Shu Wakino :
FSGSへのNMN短期集中投与はNMN・NAD消費酵素の暴走連関を抑制し糸球体硬化を抑止する,
Japanese Journal of Nephrology, Vol.64, No.3, 263, May 2022.
15. Sayo Ueda, Eriko Shibata, Masanori Tamaki, Masanori Minato, 岩城 真帆, Ikuko Shimizu, 山口 純代, 宮上 慎司, Kazuhiro Hasegawa and Shu Wakino :
急性間質性腎炎を認めた敗血症性AKIの症例,
Journal of Japanese Society for Dialysis Therapy, Vol.55, No.Suppl.1, 507, May 2022.
16. Masanori Tamaki, 宮上 慎司, 岩城 真帆, Ikuko Shimizu, 山口 純代, Masanori Minato, Sayo Ueda, Eriko Shibata, Kojiro Nagai, Kazuhiro Hasegawa and Shu Wakino :
腹膜透析導入後に膵癌を発症した1例,
Journal of Japanese Society for Dialysis Therapy, Vol.55, No.Suppl.1, 631, May 2022.
17. Ikuko Shimizu, Masanori Tamaki, 宮上 慎司, 山口 純代, Masanori Minato, Sayo Ueda, Eriko Shibata, Kazuhiro Hasegawa and Shu Wakino :
慢性大動脈解離に伴う慢性DICのため腎代替療法導入に苦慮した1例,
Journal of Japanese Society for Dialysis Therapy, Vol.55, No.Suppl.1, 663, May 2022.
18. Masanori Tamaki, 宮上 慎司, 岩城 真帆, 清水 郁子, 山口 純代, 湊 将典, Sayo Ueda, Eriko Shibata, Kazuhiro Hasegawa, Kojiro Nagai and Shu Wakino :
膵癌を合併した腹膜透析患者の1例,
第27回日本腹膜透析医学会学術集会・総会, Oct. 2021.

Et cetera, Workshop:

1. Masanori Tamaki, 湊 将典, 宮上 慎司, 岩城 真帆, 清水 郁子, 山口 純代, Sayo Ueda, Eriko Shibata, Kazuhiro Hasegawa and Shu Wakino :
ステントグラフト留置術がAVG頻回閉塞に有用であった一例,
第55回四国透析療法研究会, Oct. 2021.
2. 遠藤 理子, 宮上 慎司, 湊 将典, Masanori Tamaki, 岩城 真帆, 清水 郁子, 山口 純代, Sayo Ueda, Eriko Shibata, Kazuhiro Hasegawa and Shu Wakino :
膜性腎症に合併したIgG4関連腎臓病の一例,
第263回徳島医学会, Aug. 2021.

Grants-in-Aid for Scientific Research (KAKEN Grants Database @ NII.ac.jp)

  • 多元的フェロトーシス治療に基づく慢性腎臓病治療戦略の開発 (Project/Area Number: 23K07674 )
  • Role of NMN transporter in distal-proximal tubule interplay (Project/Area Number: 22K08354 )
  • Spiral progression of DNA damage repair, epigenetic alterations and metabolic changes in metabolic kidney diseases (Project/Area Number: 20H00535 )
  • Nampt regulates extracellular matrix composition in DKD (Project/Area Number: 19K08732 )
  • The significant role of the kidney as a central organ for metabolic organ interrelationship (Project/Area Number: 17H01562 )
  • The pathophysiology of diabetic tubulopathy and therapeutic application (Project/Area Number: 16H05315 )
  • Sirt1 and NMN mediate the tubular-PEC crosstalk. (Project/Area Number: 15K09272 )
  • Tubular- glomerular interaction nd metabolic kidney disease (Project/Area Number: 26253053 )
  • The significance of proximal tubular lesion in diabetic nephropathy and obesity-related glomerulopathy (Project/Area Number: 25293197 )
  • Claudin-1 overexpression induces the de-differentiation of podocytes. (Project/Area Number: 24591210 )
  • Kidney-specific overexpression of Sirt1 protects against chronic kidney disease. (Project/Area Number: 22790800 )
  • DDAH2 enhances insulin secretion in pancreatic islet by local NO production. (Project/Area Number: 20790654 )
  • DDAH2過剰発現マウス作成による生体におけるDDAH2の機能解析 (Project/Area Number: 18790624 )
  • Search by Researcher Number (30424162)