Tokushima University / Educator and Researcher Directory --- Izumi, Yuna

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Tokushima University ⟩ Graduate School of Biomedical Sciences ⟩ 医学域 ⟩ Medical Nutrition ⟩ Medical Nutrition ⟩ Department of Nutrition and Metabolism ⟩
Tokushima University ⟩ Graduate School of Biomedical Sciences ⟩ 医学域 ⟩ 先端基礎栄養学教育研究プロジェクト ⟩
Tokushima University ⟩ Graduate School of Medical Nutrition ⟩ Medical Nutrition ⟩

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Research

Personal Web Page

https://researchmap.jp/ymizumi (researchmap)

Field of Study

○	Life sciences [Metabolism and endocrinology]
○	Life sciences [Nutrition and health science]

Subject of Study

Book / Paper

Academic Paper (Judged Full Paper):

1.	Sonoko Yasui-Yamada, Teruhiro Morishita, Umemoto Nobuhiko, Rie Tsutsumi, Kohno Kazuyo, Shiota Shunsuke, Shinohara Mina, Yuna Izumi, Kazuhiro Nomura, Hiroshi Sakaue and Eiji Takeda : Daily Energy and Protein Intake Requirements to Prevent Body Weight Loss in Elderly Residents of Nursing Homes, Curēus, 17, 5, e83983, 2025.
2.	Takahiro Kato, Satoshi Kamiya, Soshi Narasaki, Ayako Sumii, M Yasuo Tsutsumi, Kyoka Machida, Kanako Hara, Yuna Izumi, Rie Tsutsumi and Hiroshi Sakaue : Partially Hydrolyzed Guar Gum Intake Supports the Gut Microbiota and Attenuates Inflammation during Influenza H1N1 Virus Infection in Mice., Nutrients, 15, 19, 4252, 2023. (Summary) Partially hydrolyzed guar gum (PHGG) is a soluble dietary fiber that is effective for defecation control. It influences the gut microbiota, by which it is metabolized to yield short-chain fatty acids (SCFAs), and it was also recently shown to protect against influenza infection in humans. We here investigated the effects of PHGG in a mouse model of influenza H1N1 virus infection. Eight-week-old C57BL/6 mice were fed normal chow with or without PHGG (500 mg/kg per day) for 4 weeks, infected with H1N1 at 10 weeks of age, and analyzed at 12 weeks of age. Administration of PHGG attenuated the decline in body weight induced by H1N1 infection without affecting food intake. It also ameliorated intestinal atrophy and increased the production of SCFAs including acetic acid, propionic acid, and butyric acid in the cecum, thereby preventing the inhibitory effect of H1N1 infection on SCFA production. The H1N1-induced increases in the serum concentrations of inflammatory cytokines including interferon-γ and interleukin-6 and anti-inflammatory cytokine such as interleukin-10 were all inhibited by PHGG intake. In addition, PHGG administration attenuated inflammatory gene expression in the lung and promoted both natural killer cell activity and regulatory T-cell differentiation in the spleen. Our findings suggest that the consumption of PHGG may improve the gut environment and thereby limit the inflammatory response to H1N1 infection. They may thus provide the basis for novel dietary intervention strategies to suppress the excessive inflammation associated with virus infection. (Keyword) Humans / Mice / Animals / Influenza A Virus, H1N1 Subtype / Influenza, Human / Gastrointestinal Microbiome / Mice, Inbred C57BL / Inflammation / Galactans / Mannans / Plant Gums / Fatty Acids, Volatile / Orthomyxoviridae Infections / Communicable Diseases / Dietary Fiber (Tokushima University Institutional Repository) ● Metadata: 2012861 (Link to Publication Site) ● Publication site (DOI): 10.3390/nu15194252 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 37836536 ● Search Scopus @ Elsevier (PMID): 37836536 ● Search Scopus @ Elsevier (DOI): 10.3390/nu15194252 (Tokushima University Institutional Repository: 2012861, DOI: 10.3390/nu15194252, PubMed: 37836536)

Proceeding of Domestic Conference:

1.	Sonoko Yasui-Yamada, SHIGETA Momoka, Yuna Izumi, Kazuhiro Nomura and Hiroshi Sakaue : マウス腓腹筋の体組成と水分変化を捉える生体電気インピーダンスベクトル分析の意義, 第79回日本栄養・食糧学会, May 2025.
2.	Eiji Takeda, 河野和代, 森下照大, 梅本誠彦, 吉田秀美, 川人渓, 篠原美奈, 寺尾由美, 難波由佳理, 岩瀬真菜美, Sonoko Yasui-Yamada, Rie Tsutsumi, Yuna Izumi, Kazuhiro Nomura and Hiroshi Sakaue : 介護施設後期高齢者の栄養摂取量と体重変化との関係, 第28回日本病態栄養学会学術集会, Jan. 2025.
3.	Sonoko Yasui-Yamada, Momoka Shigeta, Yuna Izumi, Seiichiro Kamimura, Kazuhiro Nomura, Yoshiaki Kitamura and Hiroshi Sakaue : 頭頸部がん化学放射線療法における生体電気インピーダンスベクトル解析の有用性の検討, 第28回日本病態栄養学会学術集会, Jan. 2025.
4.	Sonoko Yasui-Yamada, Miyu Kubo, Yuna Izumi, Kazuhiro Nomura, Seiichiro Kamimura, Hideya Kashihara, Yu Saitou, Yoshiaki Kitamura, Mitsuo Shimada, Yasuhiro Hamada and Hiroshi Sakaue : 簡便に得られるデータから作成した四肢骨格筋量を予測する回帰式の妥当性検証, 第27回日本病態栄養学会年次学術集会, Jan. 2024.
5.	Yuna Izumi, FUJIMOTO Saori, 谷口萌々花, 大村皐月, Sonoko Yasui-Yamada, 志内哲也, 岡松優子, 米代武司, Kazuhiro Nomura, 堤理恵 and Hiroshi Sakaue : 骨格筋-BAT間アミノ酸代謝連関に対する制御機構の解明, 第44回日本肥満学会学術集会, Nov. 2023.
6.	大村皐月, Yuna Izumi, Kazuhiro Nomura, Sonoko Yasui-Yamada, 志内哲也, 岡松優子, 米代武司, 堤理恵 and Hiroshi Sakaue : 臓器間アミノ酸代謝連関の調節因子としての骨格筋由来IL-6発現メカニズムの解明, 第56回栄養・食糧学会中国四国支部大会, Oct. 2023.
7.	村上遥音, Yuna Izumi, 鈴木由紀, Sonoko Yasui-Yamada, Kazuhiro Nomura, 堤理恵 and Hiroshi Sakaue : 廃用性筋萎縮の骨格筋代謝動態に対するMCT配合ケトン食の影響, 第56回栄養・食糧学会中国四国支部大会, Oct. 2023.
8.	Yuna Izumi, FUJIMOTO Saori, 谷口萌々花, 大村皐月, 志内哲也, 岡松優子, 米代武司, 黒田雅士, Kazuhiro Nomura, 堤理恵 and Hiroshi Sakaue : 骨格筋による新たな体温維持機構の発見とその制御分子の同定, 第9回日本筋学会学術集会, Aug. 2023.

Et cetera, Workshop:

1.	森下照大, 河野和代, Eiji Takeda, 梅本誠彦, 吉田秀美, 川人渓, 篠原美奈, 寺尾由美, 難波由佳理, 岩瀬真菜美, Sonoko Yasui-Yamada, Rie Tsutsumi, Yuna Izumi, Kazuhiro Nomura and Hiroshi Sakaue : 介護施設後期高齢者の栄養摂取量と体重変化との関係, 第270回徳島医学会, Feb. 2025.
2.	Sonoko Yasui-Yamada, Momoka Shigeta, Yuna Izumi, Seiichiro Kamimura, Kazuhiro Nomura, Yoshiaki Kitamura and Hiroshi Sakaue : 頭頸部がん化学放射線療法における生体電気インピーダンスベクトル解析の有用性の検討, 第270回徳島医学会, Feb. 2025.

Grants-in-Aid for Scientific Research (KAKEN Grants Database @ NII.ac.jp)

サルコペニア肥満におけるアミノ酸代謝調節機構の破綻とその制御メカニズムの解明 (Project/Area Number: 24K20670 )
メカノセンシングによる筋リモデリング活性化機構の解明と筋萎縮予防薬開発の基盤構築 (Project/Area Number: 24K02859 )
骨格筋萎縮に対する栄養学的介入法の開発を目指した臓器間アミノ酸代謝動態の解明 (Project/Area Number: 23K19926 )
Research on the diagnosis and prevention of Sarcopenia (Project/Area Number: 23K24792 )
Search by Researcher Number (20980163)