Tokushima University / Educator and Researcher Directory --- Azumi, Mai

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Tokushima University ⟩ University Hospital ⟩ 先端医科医療開発研究プロジェクト ⟩
Tokushima University ⟩ University Hospital ⟩ Clinical Division ⟩ Department of Neurosurgery, Psychiatry and Anesthesiology ⟩ Neurosurgery ⟩
Tokushima University ⟩ Faculty of Medicine ⟩ School of Medicine ⟩ Course of Integrated Brain Sciences ⟩ Neurosurgery ⟩

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Research

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Academic Paper (Judged Full Paper):

1.	Mai Azumi, Yoshifumi Mizobuchi, Nobuto Nakanishi, Kohhei Nakajima, Keijiro Hara, Toshitaka Fujihara, Manabu Ishihara, Jun Oto and Yasushi Takagi : Value of the Acute Physiology and Chronic Health Evaluation II (APACHE II) score in predicting hospital mortality for postoperative brain tumor patients in intensive care units in Japan: A retrospective case-control study, Clinical Neurology and Neurosurgery, 244(2024), 108435, 108435, 2024. (Summary) Acute Physiology and Chronic Health Evaluation II (APACHE II) is based on the data of intensive care unit (ICU) patients and often correlates with disease severity and prognosis. However, no prognostic predictors exist based on ICU admission data for patients with brain tumors, and no studies have reported an association between APACHE II and prognosis in patients with brain tumors. The Japanese Intensive Care Patients Database (JIPAD) was established to improve the quality of care delivered in intensive care medicine in Japan. We used JIPAD to examine factors associated with in-hospital mortality based on available data of postoperative patients with brain tumors admitted to the ICU. Patients aged ≥16 years enrolled in JIPAD between April 2015 and March 2018 after surgical brain tumor resection or biopsy of brain tumors. We examined factors related to outcomes at discharge based on blood tests and medical procedures performed during ICU admission, tumor type, and APACHE II score. Among the 1454 patients (male:female ratio: 1:1.1, mean age: 62 years) in the study, 32 (2.2 %) died during hospital stay. In multivariate analysis, male sex (odds ratio [OR] 2.70, [95 % confidence interval, CI 1.22-6.00]), malignant tumor (OR 2.51 [95 % CI 1.13-5.55]), and APACHE II score ≥15 (OR 2.51 [95 % CI 3.08-14.3]) were significantly associated with in-hospital mortality. By picking up cases with a high risk of in-hospital death at an early stage, it is possible to improve methods of treatment and support for the patient's family. (Keyword) Humans / Male / Female / Middle Aged / Hospital Mortality / APACHE / Japan / Brain Neoplasms / Aged / Intensive Care Units / Retrospective Studies / Case-Control Studies / Adult / Prognosis / Aged, 80 and over / Predictive Value of Tests (Link to Publication Site) ● Publication site (DOI): 10.1016/j.clineuro.2024.108435 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 38996799 ● Summary page in Scopus @ Elsevier: 2-s2.0-85198060266 (DOI: 10.1016/j.clineuro.2024.108435, PubMed: 38996799, Elsevier: Scopus)
2.	Yoshiteru Tada, Toshitaka Fujihara, Izumi Yamaguchi, Masaaki Korai, Shu Sogabe, Mai Azumi, Eiji Shikata, Koji Bando, Kohhei Nakajima, Kenji Shimada, Nobuaki Yamamoto, Hiroki Yamazaki, Yuishin Izumi, Masafumi Harada, Yasuhisa Kanematsu and Yasushi Takagi : Nonconvulsive status epilepticus in patients with acute subarachnoid hemorrhage is associated with negative arterial spin labeling on peri-ictal magnetic resonance images, Heliyon, 10, 2, E24754, 2024. (Keyword) Arterial spin labeling / Nonconvulsive status epilepticus / Subarachnoid hemorrhage (Link to Publication Site) ● Publication site (DOI): 10.1016/j.heliyon.2024.e24754 (Link to Search Site for Scientific Articles) ● Summary page in Scopus @ Elsevier: 2-s2.0-85182583112 (DOI: 10.1016/j.heliyon.2024.e24754, Elsevier: Scopus)

Proceeding of Domestic Conference:

1.	Mai Azumi, Yohjiroh Sunada, Kohhei Nakajima, Keijiro Hara and Yasushi Takagi : 呼吸障害を呈しForamen Magnum Decompression(FMD)を行った軟骨無形成症の乳児例, 第53回日本小児神経外科学会, Jun. 2025.
2.	Yosuke Tominaga, Mai Azumi, Yohjiroh Sunada, Kohhei Nakajima, Keijiro Hara and Yasushi Takagi : Foramen Magnum Decompression(FMD)を行った軟骨無形成症の乳児例, 第99回日本脳神経外科学会中国四国支部学術集会, Apr. 2025.
3.	Yoshiteru Tada, Toshitaka Fujihara, Mai Azumi, Yoshihito Matsuzaki, Tatsuo Mori, Mutsuki Nakano, 飯田幸治 and Yasushi Takagi : 中心領域のてんかん焦点切除術を行ったスタージ・ウェーバー症候群の1例, 第12回全国てんかんセンター協議会総会, Mar. 2025.
4.	Mai Azumi, Kohhei Nakajima, Hiroki Ishibashi and Yasushi Takagi : Ideas for avoiding ventral complications in pediatric hydrocephalus surgery at our hospitalOne case where laparoscopy was effective and future efforts, 日本脳神経外科学会第83回学術総会, Oct. 2024.
5.	Toshitaka Fujihara, Yoshiteru Tada, Mai Azumi, Keijiro Hara, Kohhei Nakajima and Yasushi Takagi : Clinical characteristics and outcome of status epilepticus in patients with brain tumor, 日本脳神経外科学会第83回学術総会, Oct. 2024.
6.	Keijiro Hara, Mai Azumi, Toshitaka Fujihara, Kohhei Nakajima and Yasushi Takagi : 開頭摘出術を行った転移性脳腫瘍の術後成績, 日本脳神経外科学会第83回学術総会, Oct. 2024.
7.	Toshitaka Fujihara, Kohhei Nakajima, Mai Azumi, Keijiro Hara and Yasushi Takagi : Tips for temporal lobectomy for malignant brain tumor of temporal lobe, 第29回日本脳腫瘍の外科学会, Oct. 2024.
8.	砂田陽二郎, Mai Azumi, Kohhei Nakajima, Toshitaka Fujihara, Keijiro Hara and Yasushi Takagi : 成人発症sellar Atypical Teratoid/Rhabdoid Tumorの一例, 第38回中国四国脳腫瘍研究会, Sep. 2024.
9.	Toshitaka Fujihara, Yoshiteru Tada, Kohhei Nakajima, Keijiro Hara, Mai Azumi and Yasushi Takagi : Epilepsy and perioperative seizures in surgical cases of supratentorial meningioma, 第57回日本てんかん学会学術集会, Sep. 2024.
10.	Mai Azumi, Kohhei Nakajima, Hiroki Ishibashi and Yasushi Takagi : Ideas for avoiding ventral complications in pediatric hydrocephalus surgery at our hospital - one case where laparoscopy was effective and future effort, 第52回日本小児神経外科学会, Jun. 2024.