Tokushima University / Educator and Researcher Directory --- Nakajima, Miyo

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Tokushima University ⟩ University Hospital ⟩ Clinical Division ⟩ Department of Ophthalmology, Otolaryngology, Dermatology, Orthopedics, and Plastic Surgery ⟩ Dermatology ⟩
Tokushima University ⟩ University Hospital ⟩ 先端医科医療開発研究プロジェクト ⟩
Tokushima University ⟩ Faculty of Medicine ⟩ School of Medicine ⟩ Course of Pathologic Medicine for Senso-motoric System ⟩ Dermatological Science ⟩

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Research

Field of Study

Subject of Study

Book / Paper

Academic Paper (Judged Full Paper):

1.	Kazutoshi Murao, Kanako Yamasaki, Hirokazu Agawa, Miyo Nakajima, Maiko Iwasaka and Yoshiaki Kubo : Bowen disease on the dorsum of the foot associated with human papillomavirus type 16, The Journal of Medical Investigation : JMI, 69, 1,2, 152-154, 2022. (Summary) A 94 years old Japanese female was presented to our hospital with a skin lesion on her left foot. A physical examination found a markedly hyperkeratotic reddish-brown plaque, measuring 3 cm in diameter. A biopsy specimen showed prominent papillomatosis, hyperkeratosis, and atypical keratinocytes throughout the epidermis. Individual cell keratinization, multinucleated keratinocytes, and many keratinocytes with clear cytoplasm were seen. We excised the lesion, and the skin grafting was used for covering the skin defect. We investigated whether human papillomavirus (HPV) was present in the lesion, and HPV 16 DNA was detected using the polymerase chain reaction. Immunohistochemical analysis showed several HPV-positive cells in the upper epidermis. In addition, the tumor cells showed strong and diffuse expression of p16INK4a. Bowen disease (BD) is an intraepidermal squamous cell carcinoma. The precise pathogenesis of BD is unclear, but it involves various factors. HPV infection is one of these factors and is a well-known cause of BD of the genitalia and fingers. It has been shown that some BD lesions occurring at other locations are also associated with HPV. Dysregulation of the Rb/p16INK4a pathway is considered to play an important role in HPV-induced BD, but the precise mechanism remains to be elucidated. J. Med. Invest. 69 : 152-154, February, 2022. (Keyword) Aged, 80 and over / Bowen's Disease / Cyclin-Dependent Kinase Inhibitor p16 / female / Human papillomavirus 16 / Humans / Papillomaviridae / Papillomavirus Infections (Tokushima University Institutional Repository) ● Metadata: 2009903 (Link to Publication Site) ● Publication site (DOI): 10.2152/jmi.69.152 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 35466139 ● Search Scopus @ Elsevier (PMID): 35466139 ● Search Scopus @ Elsevier (DOI): 10.2152/jmi.69.152 (Tokushima University Institutional Repository: 2009903, DOI: 10.2152/jmi.69.152, PubMed: 35466139)

Et cetera, Workshop:

1.	Kazutoshi Murao, Kanako Yamasaki, 木下華子, Shoko Miyamoto, Miyo Nakajima, Ayaka Iwawaki, 矢野由夏, 角真衣 and Yoshiaki Kubo : 最近当科で経験した手指のBowen病6例について, 第42回日本皮膚悪性腫瘍学会学術大会, Jul. 2026.
2.	西村真衣, Riho Nakano, Miyo Nakajima, Kanako Yamasaki and Kazutoshi Murao : フルオロウラシルによる中毒性表皮壊死症の1例, 第164回日本皮膚科学会徳島地方会, Jun. 2026.
3.	Kazutoshi Murao, Ayaka Iwawaki, Miyo Nakajima and Yoshiaki Kubo : 抗 NXP-2 抗体陽性であった Wong-type 皮膚筋炎の小児例, 第42回日本臨床皮膚科医会総会・臨床学術大会, Apr. 2026.
4.	吉田ありさ, Shoko Miyamoto, Miyo Nakajima, Kazutoshi Murao, Yoshiaki Kubo, 古賀浩嗣, 石井文人 and 村尾牧子 : 重篤な粘膜疹を伴い治療に難渋した腫瘍随伴性天疱瘡の1例, 第77回日本皮膚科学会西部支部学術大会, Oct. 2025.
5.	Miyo Nakajima, 吉田ありさ, Kazutoshi Murao, Yutaka Kinoshita, Yasutoshi Hida, 福原耕作 and 松下貴史 : 抗NXP抗体陽性小児皮膚筋炎の1例, 第162回日本皮膚科学会徳島地方会, Jun. 2025.
6.	遠藤理子, Miyo Nakajima, Kazutoshi Murao and Yoshiaki Kubo : 末梢血幹細胞移植後に生じた汗孔角化症の1例, 第124回日本皮膚科学会総会, May 2025.
7.	吉田ありさ, Ayaka Iwawaki, Miyo Nakajima, Mariko Niki and Yoshiaki Kubo : アザチオプリンが著効したリウマトイド血管炎の1例, 第161回日本皮膚科学会徳島地方会, Nov. 2024.
8.	Miyo Nakajima, 高野浩章 and 宮澤真理 : McCune-Albright症候群の1例, 第161回日本皮膚科学会徳島地方会, Nov. 2024.
9.	六車あずさ, Miyo Nakajima, 木下華子, Kazutoshi Murao and 宮岡由規 : 顔面に多発した偽リンパ腫の1例, 第161回日本皮膚科学会徳島地方会, Nov. 2024.
10.	Miyo Nakajima, Kanako Yamasaki, Kazutoshi Murao, Yoshiaki Kubo, Sho Takaoka, Gou Satou, Yoshiaki Kitamura, 古賀浩嗣 and 石井文人 : 診断に苦慮したLAD-1に対するIgA抗体丹毒陽性粘膜類天疱瘡の1例, 第76回日本皮膚科学会西部支部学術大会, Sep. 2024.

Grants-in-Aid for Scientific Research (KAKEN Grants Database @ NII.ac.jp)

Search by Researcher Number (11030297)