Tokushima University / Educator and Researcher Directory --- Murao, Kazutoshi

Personal Web Page

https://researchmap.jp/read0108803 (researchmap)

Field of Study

○	Medicine

Subject of Study

○

Book / Paper

Book:

1.	Kazutoshi Murao : 血液透析診療指針, TOKYO IGAKUSHA, Tokyo, Jun. 2021.
2.	Kazutoshi Murao, Yoshiaki Kubo, D Fukumoto, Kazuya Matsumoto and Seiji Arase : Verrucous carcinoma of the scalp associated with human papillomavirus type 33, Blackwell Publishing Ltd, Oct. 2005. (Summary) Verrucous carcinoma (VC) is a low-grade, well-differentiated squamous cell carcinoma of the skin or mucosae, and human papillomavirus (HPV) infection has been considered to be one of the causative factors of VC at three main sites, including the oral cavity, the genitoanal region, and the foot. However, the relationship between cutaneous VC at other sites and HPV infection remains obscure. We describe a rare case of cutaneous VC originating in a burn scar on the scalp and our attempt to find HPV infection in the lesion. We investigated the presence of HPV by polymerase chain reaction-restriction fragment length polymorphisms and immunohistochemical analysis. HPV type 33 was detected in the lesion, and positive stains for HPV were observed in several cell nuclei at the upper stratum malpighi. Since HPV type 33, as well as HPV types 16 and 18, is regarded as a high-risk, mucosal type, HPV type 33 infection likely contributed to the development of the lesion. We suggest that HPV infection should be relevant to a subset of cutaneous VC. (Keyword) Aged, 80 and over / Carcinoma, Verrucous / Female / Humans / Immunohistochemistry / Oncogene Proteins, Viral / Papillomavirus Infections / Polymerase Chain Reaction / Polymorphism, Restriction Fragment Length / Scalp / Skin Neoplasms / Treatment Outcome (Link to Publication Site) ● Publication site (DOI): 10.1111/j.1524-4725.2005.31222 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 16188198 ● Search Scopus @ Elsevier (PMID): 16188198 ● Search Scopus @ Elsevier (DOI): 10.1111/j.1524-4725.2005.31222 (DOI: 10.1111/j.1524-4725.2005.31222, PubMed: 16188198)
3.	Kazutoshi Murao, Yoshiaki Kubo, Kosaku Fukuhara, Kazuya Matsumoto and Seiji Arase : Three cases of Bowen's disease on the lower abdomen associated with high-risk types 16, 33, and 59 of human papillomavirus, Elsevier Science, Apr. 2005. (Keyword) Abdomen / Aged / Bowen's Disease / Human papillomavirus 16 / Humans / Male / Papillomaviridae / Papillomavirus Infections / Risk Factors / Skin Neoplasms (Link to Publication Site) ● Publication site (DOI): 10.1016/j.jaad.2004.11.042 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 15793544 ● Search Scopus @ Elsevier (PMID): 15793544 ● Search Scopus @ Elsevier (DOI): 10.1016/j.jaad.2004.11.042 (DOI: 10.1016/j.jaad.2004.11.042, PubMed: 15793544)
4.	Kazutoshi Murao, Yoshiaki Kubo, Hirotsugu Takiwaki, Seiji Arase and Kazuya Matsumoto : Bowen's disease on the sole: p16INK4a overexpression associated with human papillomavirus type 16, Blackwell Publishing Ltd, Jan. 2005. (Summary) We report a case of Bowen's disease on the sole presenting clinically as an exophytic, blackish-grey, verrucous tumour, and showing human papillomavirus (HPV) type 16 on analysis with polymerase chain reaction. Positive stains for HPV particles by immunohistochemical analysis were limited to several cell nuclei at the upper stratum Malpighii. However, all the tumour cells in the epidermis exhibited strong and diffuse nuclear and cytoplasmic stains for the tumour suppressor protein p16INK4a. We speculate that dysregulation of the retinoblastoma/p16INK4a pathway may be involved in the pathogenesis of the lesion, and p16INK4a overexpression might serve as a useful surrogate marker for identifying Bowen's disease harbouring high-risk types of HPV infection. (Keyword) Adult / Bowen's Disease / Cyclin-Dependent Kinase Inhibitor p16 / DNA, Viral / Female / Foot Diseases / Humans / Papillomaviridae / Papillomavirus Infections / Skin Neoplasms / Tumor Markers, Biological (Link to Publication Site) ● Publication site (DOI): 10.1111/j.1365-2133.2005.06365.x (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 15656821 ● Search Scopus @ Elsevier (PMID): 15656821 ● Search Scopus @ Elsevier (DOI): 10.1111/j.1365-2133.2005.06365.x (DOI: 10.1111/j.1365-2133.2005.06365.x, PubMed: 15656821)
5.	Kazutoshi Murao, Yasushi Fukui, Satoshi Numoto and Yoshio Urano : Tailgut Cyst as a Subcutaneous Tumor at the Coccygeal Region, Lippincott Williams & Wilkins, Jun. 2003. (Keyword) Adult / Cysts / Female / Hamartoma / Humans / Rectal Diseases / Sacrococcygeal Region / Treatment Outcome (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 12775995 ● Search Scopus @ Elsevier (PMID): 12775995 (PubMed: 12775995)
6.	Kazutoshi Murao : 神経症性擦傷, KANEHARA & CO., LTD., Mar. 2003.
7.	Kazutoshi Murao : 肛囲に生じた基底細胞癌の1例, IGAKU-SHOIN Ltd.Tokyo,Japan, Dec. 2002.
8.	Kazutoshi Murao, 沼本敏 and 瀬渡洋道 : 小児に生じた隆起性皮膚線維肉腫の1例, KANEHARA & CO., LTD., May 2002.
9.	Kazutoshi Murao : Tufted Hair Folliculitiesの1例, KANEHARA & CO., LTD., 2001. (Keyword) Tufted hair folliculitis / 瘢痕性脱毛
10.	Kazutoshi Murao and 渡辺浩良 : 頭皮欠損症を合併した13トリソミー症候群の1例, KANEHARA & CO., LTD., 2001. (Keyword) 頭皮欠損症 / 13トリソミー症候群

Academic Paper (Judged Full Paper):

1.	Kazutoshi Murao, Yuko Hori, Riko Endo, Ayaka Iwawaki and Yoshiaki Kubo : A case of vitiligo that followed the path of a varicose vein in the lower leg., The Journal of Medical Investigation : JMI, Vol.71, No.1,2, 177-178, 2024. (Tokushima University Institutional Repository) ● Metadata: 119476 (Link to Publication Site) ● Publication site (DOI): 10.2152/jmi.71.177 (Link to Search Site for Scientific Articles) ● Search Scopus @ Elsevier (DOI): 10.2152/jmi.71.177 (Tokushima University Institutional Repository: 119476, DOI: 10.2152/jmi.71.177)
2.	Kazutoshi Murao, 宇都宮正裕 and Yoshiaki Kubo : A case of intralymphatic histiocytosis mimicking lymphangioma circumscriptum associated with a puncture wound caused by a thorn, Journal of the Japan Organization of Clinical Dermatologists, Vol.41, No.1, 55-59, 2024. (Keyword) intralymphatic histiocytosis / リンパ管拡張 / 棘 / 組織球 / 外傷 / lymphangiectasia / thorn / histiocyte / trauma (Link to Publication Site) ● Publication site (DOI): 10.3812/jocd.41.55 (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1390299682763670272 ● Search Scopus @ Elsevier (DOI): 10.3812/jocd.41.55 (DOI: 10.3812/jocd.41.55, CiNii: 1390299682763670272)
3.	Rie Hayashi, Kanako Yamasaki, Tetsuya Hida, Kazutoshi Murao and Yoshiaki Kubo : ヒト乳頭腫ウイルスが検出された肛囲のBowen病・Bowen癌の3例, Japanese Journal of Clinical Dermatology, Vol.77, No.12, 1085-1090, 2023. (Link to Publication Site) ● Publication site (DOI): 10.11477/mf.1412207162 (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1390017046610681344 ● Search Scopus @ Elsevier (DOI): 10.11477/mf.1412207162 (DOI: 10.11477/mf.1412207162, CiNii: 1390017046610681344)
4.	Kazutoshi Murao and Yoshiaki Kubo : Podoplanin-positive cells located in the basal layer of Bowen disease include tumor cells with cancer stem cell properties., The Journal of Dermatology, Vol.50, No.12, 1560-1567, 2023. (Summary) Podoplanin (PDPN) is widely used as a marker of lymphatic endothelial cells. PDPN is also involved in tumor progression, and upregulated PDPN expression is often found in various cancers. In this study, we first immunohistochemically examined PDPN expression in 87 cases of Bowen disease. Positive expression was detected in 64.4% of Bowen disease specimens, and the positive cells were exclusively located in the basal layer and corresponded to palisaded basal cells (PBCs). PBCs have been considered to be residual normal keratinocytes so far, but PDPN expression in cancers is generally associated with poor clinical outcomes. We also examined PDPN expression in 27 cases of Bowen carcinoma. Diffuse and strong PDPN expression was detected in 22.2% of Bowen carcinoma specimens, and another 22.2% showed PDPN expression at the leading edges of tumor nests. These results prompted us to determine whether PDPN-positive cells are more tumorigenic than PDPN-negative cells. We cultured Bowen disease cells using a three-dimensional (3D) cell culture system and examined PDPN expression. In the cultured Bowen disease tissue, PDPN expression was again detected in the basal layer. Then, we isolated 1.2 × 10 PDPN-positive and -negative cells from the 3D organotypic culture of Bowen disease by fluorescence-activated cell sorting analysis and compared their tumorigenicity using 3D culture. The PDPN-positive tumor cells were able to regenerate Bowen disease tissue, but the PDPN-negative tumor cells were not. In addition, the regenerated Bowen disease tissue derived from the PDPN-positive cells exhibited PDPN expression in its basal layer, as the parental Bowen disease tissue did. These results indicate that PDPN-positive cells include tumor cells with cancer stem cell properties. Although the precise mechanism through which PDPN expression is involved in the pathogenesis of Bowen disease needs to be determined, PDPN may be a novel druggable target for Bowen disease. (Keyword) Humans / Bowen's Disease / Membrane Glycoproteins / Endothelial Cells / Skin Neoplasms / Neoplastic Stem Cells (Link to Publication Site) ● Publication site (DOI): 10.1111/1346-8138.16943 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 37658727 ● Search Scopus @ Elsevier (PMID): 37658727 ● Search Scopus @ Elsevier (DOI): 10.1111/1346-8138.16943 (DOI: 10.1111/1346-8138.16943, PubMed: 37658727)
5.	岩脇文香, Yoshihiro Matsudate, 田蒔舞子, Mariko Niki, Kazutoshi Murao and Yoshiaki Kubo : 染毛剤により生じたchemical leukodermaの1例, Hifuka No Rinsho, Vol.65, No.10, 1553-1556, 2023. (Keyword) chemical leukoderma / p-phen-ylenediamine (Link to Publication Site) ● Publication site (DOI): 10.18888/hi.0000004161 (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1390860465164347648 ● Search Scopus @ Elsevier (DOI): 10.18888/hi.0000004161 (DOI: 10.18888/hi.0000004161, CiNii: 1390860465164347648)
6.	横田綾, Kazutoshi Murao, 水口潤 and 川島周 : 透析患者における粉瘤発生についての検討, Japanese Journal of Clinical Dermatology, Vol.77, No.3, 271-275, 2023. (Link to Publication Site) ● Publication site (DOI): 10.11477/mf.1412206923 (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1390295270242235904 ● Search Scopus @ Elsevier (DOI): 10.11477/mf.1412206923 (DOI: 10.11477/mf.1412206923, CiNii: 1390295270242235904)
7.	Kanako Yamasaki, 湊優子, 中島美世, Mariko Niki, Kazutoshi Murao, Yoshiaki Kubo and 小川瑛 : JAK阻害薬投与中の関節リウマチ患者に発症し蜂窩織炎様の所見を呈した皮膚クリプトコッカス症の1例, 皮膚科の臨床, Vol.65, No.2, 179-183, 2023.
8.	Kazutoshi Murao and Yoshiaki Kubo : A case of cutaneous collagenous vasculopathy, Journal of the Japan Organization of Clinical Dermatologists, Vol.39, No.6, 765-768, 2022. (Keyword) cutaneous collagenous vasculopathy / 毛細血管拡張 / PAS染色 / 抗collagen IV抗体 / telangiectasia / periodic acid Schiff stain / anti-collagen IV antibody (Link to Publication Site) ● Publication site (DOI): 10.3812/jocd.39.765 (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1390576591777414656 ● Search Scopus @ Elsevier (DOI): 10.3812/jocd.39.765 (DOI: 10.3812/jocd.39.765, CiNii: 1390576591777414656)
9.	Satoshi Murao, Kazutoshi Murao, Tsuyoshi Nagata, Misato Shimizu and Yumi Miyai : Repeated insulin injection without site rotation affects skin thickness - ultrasonographic and histological evaluation, Journal of Diabetes Investigation, Vol.13, No.6, 997-1003, 2022. (Summary) The influence of repeated insulin injection on subcutaneous tissue is known, but its impact on the skin is unclear. Therefore, this study aimed to elucidate the impact of repeated insulin injections on the skin. The properties of the skin and the subcutaneous tissue were evaluated in 52 insulin-treated adult patients with diabetes with abnormal findings at the site of self-injection (36 with subcutaneous nodules, 16 with suspected subcutaneous tissue induration) by ultrasonography. In all subjects, both normal and abnormal areas were examined. In addition, skin biopsies were performed in four subjects. The skin thickness of the normal and abnormal skin sites was 1.95 (1.60, 2.50) and 2.80 (2.27, 3.30) mm, respectively (median (first quartile, third quartile)), (P < 0.001). The biopsy specimens revealed slightly thickened and tight bundles of collagen in the dermis. Three patients had amyloid deposits in the subcutaneous tissue, and one also showed these in the dermis. These were positively stained for insulin antibody. Repeated insulin injection procedures result in skin thickening. Increased collagen fibers and possibly amyloid deposition in the dermis may be involved. The results reaffirmed the importance of appropriate site rotation in insulin injection and revealed the usefulness of ultrasonographic skin examination in evaluating the self-injection procedure. (Keyword) Adult / Amyloidosis / Collagen / Humans / Injections, Subcutaneous / Insulin / Rotation / Skin (Tokushima University Institutional Repository) ● Metadata: 117560 (Link to Publication Site) ● Publication site (DOI): 10.1111/jdi.13753 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 35060349 ● Search Scopus @ Elsevier (PMID): 35060349 ● Search Scopus @ Elsevier (DOI): 10.1111/jdi.13753 (Tokushima University Institutional Repository: 117560, DOI: 10.1111/jdi.13753, PubMed: 35060349)
10.	Tomoya Mizutani, Takeshi Ishigami, Kazutoshi Murao, Yoshiaki Kubo, 中山泰介, Takashi Kitaichi, Tetsuya Kitagawa and 毛山剛 : 遺残坐骨動脈により生じた足背部難治性皮膚潰瘍の1例, Hifuka No Rinsho, Vol.64, No.3, 403-406, 2022. (Keyword) 遺残坐骨動脈 / 皮膚潰瘍 / 下肢虚血 / イザンザコツドウミャク / ヒフカイヨウ / カシキョケツ (Link to Publication Site) ● Publication site (DOI): 10.18888/hi.0000003160 (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1390291767698846976 ● Search Scopus @ Elsevier (DOI): 10.18888/hi.0000003160 (DOI: 10.18888/hi.0000003160, CiNii: 1390291767698846976)
11.	Kazutoshi Murao, Kanako Yamasaki, Hirokazu Agawa, Mio Nakajima, Maiko Iwasaka and Yoshiaki Kubo : Bowen disease on the dorsum of the foot associated with human papillomavirus type 16, The Journal of Medical Investigation : JMI, Vol.69, No.1,2, 152-154, 2022. (Summary) A 94 years old Japanese female was presented to our hospital with a skin lesion on her left foot. A physical examination found a markedly hyperkeratotic reddish-brown plaque, measuring 3 cm in diameter. A biopsy specimen showed prominent papillomatosis, hyperkeratosis, and atypical keratinocytes throughout the epidermis. Individual cell keratinization, multinucleated keratinocytes, and many keratinocytes with clear cytoplasm were seen. We excised the lesion, and the skin grafting was used for covering the skin defect. We investigated whether human papillomavirus (HPV) was present in the lesion, and HPV 16 DNA was detected using the polymerase chain reaction. Immunohistochemical analysis showed several HPV-positive cells in the upper epidermis. In addition, the tumor cells showed strong and diffuse expression of p16INK4a. Bowen disease (BD) is an intraepidermal squamous cell carcinoma. The precise pathogenesis of BD is unclear, but it involves various factors. HPV infection is one of these factors and is a well-known cause of BD of the genitalia and fingers. It has been shown that some BD lesions occurring at other locations are also associated with HPV. Dysregulation of the Rb/p16INK4a pathway is considered to play an important role in HPV-induced BD, but the precise mechanism remains to be elucidated. J. Med. Invest. 69 : 152-154, February, 2022. (Keyword) Aged, 80 and over / Bowen's Disease / Cyclin-Dependent Kinase Inhibitor p16 / Female / Human papillomavirus 16 / Humans / Papillomaviridae / Papillomavirus Infections (Tokushima University Institutional Repository) ● Metadata: 117028 (Link to Publication Site) ● Publication site (DOI): 10.2152/jmi.69.152 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 35466139 ● Search Scopus @ Elsevier (PMID): 35466139 ● Search Scopus @ Elsevier (DOI): 10.2152/jmi.69.152 (Tokushima University Institutional Repository: 117028, DOI: 10.2152/jmi.69.152, PubMed: 35466139)
12.	Satoshi Murao and Kazutoshi Murao : Multiple skin ulceration and itch-scratch cycle in a diabetic patient, Journal of Diabetes Investigation, Vol.12, No.11, 2102-2103, 2021. (Summary) Diabetic patients sometimes present generalized pruritus. Severe itching can cause an itch-scratch cycle, resulting in distress and impaired quality of life, but skin ulceration is a rare manifestation. (Keyword) Diabetes Mellitus, Type 2 / Humans / Male / Medical Illustration / Middle Aged / Prurigo / Pruritus / Quality of Life / Skin Ulcer (Link to Publication Site) ● Publication site (DOI): 10.1111/jdi.13560 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 33963823 ● Search Scopus @ Elsevier (PMID): 33963823 ● Search Scopus @ Elsevier (DOI): 10.1111/jdi.13560 (DOI: 10.1111/jdi.13560, PubMed: 33963823)
13.	山崎佳那子, Rie Hayashi, Yoshihiro Matsudate, Kazutoshi Murao and Yoshiaki Kubo : 下腿蜂窩織炎様の臨床像で再発した節外性NK/T細胞リンパ腫の1例, Hifuka No Rinsho, Vol.63, No.5, 687-690, 2021. (Keyword) 節外性NK/T細胞リンパ腫 / 蜂窩織炎 / EBER / 放射線療法 / セツガイセイ NK/Tサイボウリンパシュ / ホウカシキエン / ホウシャセンリョウホウ (Link to Publication Site) ● Publication site (DOI): 10.18888/hi.0000002553 (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1390569623316929280 ● Search Scopus @ Elsevier (DOI): 10.18888/hi.0000002553 (DOI: 10.18888/hi.0000002553, CiNii: 1390569623316929280)
14.	Kazutoshi Murao and Yoshiaki Kubo : 足底に生じ，HPV33型DNAを検出したBowen病の1例, Journal of the Japan Organization of Clinical Dermatologists, Vol.38, No.1, 57-61, 2021. (Link to Publication Site) ● Publication site (DOI): 10.3812/jocd.38.57 (Link to Search Site for Scientific Articles) ● Search Scopus @ Elsevier (DOI): 10.3812/jocd.38.57 (DOI: 10.3812/jocd.38.57)
15.	山﨑佳那子, 宮本千暁, Mio Yada, Yoshihiro Matsudate, Kazutoshi Murao and Yoshiaki Kubo : 急速に腎障害が進行したクリオグロブリン血症性血管炎, Practical Dermatology, Vol.42, No.6, 498-501, 2020. (Link to Publication Site) ● Publication site (DOI): 10.24733/pd.0000002047 (Link to Search Site for Scientific Articles) ● Search Scopus @ Elsevier (DOI): 10.24733/pd.0000002047 (DOI: 10.24733/pd.0000002047)
16.	Maiko Sogawa, Kazutoshi Murao, Yoshiaki Kubo, Kei Daizumoto and Hiro-omi Kanayama : 顔面に皮疹を認めなかったBirt-Hogg-Dube症候群の1例, Japanese Journal of Clinical Dermatology, Vol.73, No.13, 1089-1094, 2019. (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1390565134811658112 (CiNii: 1390565134811658112)
17.	Maiko Sogawa, Yoshihiro Matsudate, Kazutoshi Murao, Yoshiaki Kubo and Masahiro Utsunomiya : 疱疹状天疱瘡を合併した尋常性乾癬の1例, Japanese Journal of Clinical Dermatology, Vol.73, No.13, 1059-1064, 2019. (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1390846609788060544 (CiNii: 1390846609788060544)
18.	Maiko Iwasaka, Yoshihiro Matsudate, Maiko Tamaki, Kazutoshi Murao and Yoshiaki Kubo : 入院中に生じた緑膿菌性毛包炎の母子例, Hifuka No Rinsho, Vol.61, No.9, 1449-1453, 2019. (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1390282763137538048 (CiNii: 1390282763137538048)
19.	Yoshihiro Matsudate, Kazutoshi Murao, Yoshiaki Kubo and 高橋収 : Erythema Multiforme Associated with Chemical Burn Due to the Herbicides Alachlor, Hifuka No Rinsho, Vol.61, No.2, 225-228, 2019. (Keyword) 多形紅斑 / アラクロール / 除草剤 / 接触皮膚炎 (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1390001288159209728 (CiNii: 1390001288159209728)
20.	Kazutoshi Murao and Yoshiaki Kubo : Condyloma acuminatum of the nipple resembling seborrheic keratosis, Journal of the Japan Organization of Clinical Dermatologists, Vol.36, No.1, 35-38, 2019. (Summary) A 25-year-old Japanese female presented with a skin lesion on her left nipple. The lesion had been present for three months and was increasing in size. A physical examination revealed a brown hyperkeratotic verrucous nodule on her left nipple. A histological examination of a biopsy specimen showed hyperkeratosis, papillo-matosis, and acanthosis. There were several koilocytes in the upper epidermis. Positive staining for human papillomavirus (HPV) particles by immunohistochemical analysis was seen in several cell nuclei at the upper malpighian layer. Mucous-type HPV DNA was detected in the lesion using the polymerase chain reaction (PCR), and it was identified as HPV type 6 by direct sequencing of the PCR product. We treated the patient by cryotherapy with liquid nitrogen, and the lesion disappeared. Condyloma acuminatum of the nipple is very rare. Interestingly, most reported clinical cases exhibit a seborrheic keratosis-like appearance. Dermatologists should consider condyloma acuminatum in cases in which seborrheic keratosis-like lesions are shown on the nipple. (Keyword) condylomaacuminatum / humanpapillomavirus / nipple / seborrheickeratosis (Link to Publication Site) ● Publication site (DOI): 10.3812/jocd.36.35 (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1390567172583001600 ● Search Scopus @ Elsevier (DOI): 10.3812/jocd.36.35 (DOI: 10.3812/jocd.36.35, CiNii: 1390567172583001600)
21.	阿河弘和, Yoshihiro Matsudate, Kenji Hirose, Kazutoshi Murao, Yoshihisa Sakao and Yoshiaki Kubo : CASE REPORTS : Contact Dermatitis Syndrome Due to Betamethasone Valerate, Hifuka No Rinsho, Vol.61, No.1, 63-66, 2019. (Keyword) ベタメタゾン吉草酸エステル / 接触皮膚炎症候群 (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1390845713090947840 (CiNii: 1390845713090947840)
22.	Yoshihiro Matsudate, 木下華子, Tomoya Mizutani, Kazutoshi Murao and Yoshiaki Kubo : A case of cutaneous anaplastic large cell lymphoma with pseudocarcinomatous hyperplasia, Japanese Journal of Clinical Dermatology, Vol.72, No.12, 999-1004, 2018. (Keyword) 偽癌性増殖 / リンパ腫様丘疹症 / 皮膚未分化大細胞リンパ腫 / 原発性皮膚CD30陽性リンパ増殖異常症 (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1390845713027619712 (CiNii: 1390845713027619712)
23.	木下華子, Yoshihiro Matsudate, Kazutoshi Murao and Yoshiaki Kubo : オウゴンクジャクヒバによる接触皮膚炎症候群の1例, Hifuka No Rinsho, Vol.60, No.3, 430-431, 2018. (Link to Publication Site) ● Publication site (DOI): 10.18888/hi.0000000640 (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1390845713092528768 ● Search Scopus @ Elsevier (DOI): 10.18888/hi.0000000640 (DOI: 10.18888/hi.0000000640, CiNii: 1390845713092528768)
24.	Yoshihiro Matsudate, Kazutoshi Murao, 浦野芳夫 and Yoshiaki Kubo : 留置針外套による接触皮膚炎, Practical Dermatology, Vol.39, No.7, 735-738, 2017. (Link to Publication Site) ● Publication site (DOI): 10.24733/J01268.2017304604 (Link to Search Site for Scientific Articles) ● Search Scopus @ Elsevier (DOI): 10.24733/J01268.2017304604 (DOI: 10.24733/J01268.2017304604)
25.	横田綾, Kazutoshi Murao, 水口潤 and 川島周 : 透析による難治性皮膚瘙痒症に対するNarrow-band UVB療法の試み, Hifuka No Rinsho, Vol.59, No.3, 347-351, 2017. (Keyword) narrow-band UVB / 慢性腎不全 / 皮膚瘙痒症 (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1524232504921261568 (CiNii: 1524232504921261568)
26.	木下華子, Yoshihiro Matsudate, Kazutoshi Murao, Yoshiaki Kubo, 長江哲夫 and 荒瀬誠治 : ゴム加硫促進剤による接触皮膚炎症候群の1例, Hifuka No Rinsho, Vol.58, No.13, 1921-1925, 2016. (Keyword) 加硫促進剤 / ジチオカーバメイト系化合物 / 接触皮膚炎症候群 (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1523106605479673472 (CiNii: 1523106605479673472)
27.	Mayu Yuasa, Kazutoshi Murao and Yoshiaki Kubo : 陰茎に生じたCalciphylaxisの1例, Hifuka No Rinsho, Vol.58, No.12, 1904-1905, 2016. (Link to Publication Site) ● Publication site (DOI): 10.18888/J01266.2017081165 (Link to Search Site for Scientific Articles) ● Search Scopus @ Elsevier (DOI): 10.18888/J01266.2017081165 (DOI: 10.18888/J01266.2017081165)
28.	祖川麻衣子, Yoshihiro Matsudate, Kazutoshi Murao and Yoshiaki Kubo : ソラフェニブ投与中に生じたケラトアカントーマの1例, Hifuka No Rinsho, Vol.58, No.9, 1353-1356, 2016. (Keyword) ソラフェニブ / ケラトアカントーマ (Link to Publication Site) ● Publication site (DOI): 10.18888/j01266.2016373702 (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1390282763137435776 ● Search Scopus @ Elsevier (DOI): 10.18888/j01266.2016373702 (DOI: 10.18888/j01266.2016373702, CiNii: 1390282763137435776)
29.	Yoshihiro Matsudate, Kazutoshi Murao and Yoshiaki Kubo : ヒアレインミニ点眼液とミドリンP点眼液による接触皮膚炎, Practical Dermatology, Vol.37, No.5, 475-478, 2015. (Link to Publication Site) ● Publication site (DOI): 10.24733/J01268.2015266464 (Link to Search Site for Scientific Articles) ● Search Scopus @ Elsevier (DOI): 10.24733/J01268.2015266464 (DOI: 10.24733/J01268.2015266464)
30.	Rie Yamamura, Kazuhiro Furukita, Kazutoshi Murao and Yoshiaki Kubo : Graham-Little症候群, 皮膚病診療, Vol.37, No.4, 345-348, 2015.
31.	Tetsuya Hida, Kazutoshi Murao, Mika Oshima, Takeshi Ishigami and Yoshiaki Kubo : A case of pyoderma gangrenosum associated with anterior necrotizing scleritis in a patient with ulcerative colitis., International Journal of Dermatology, Vol.54, No.7, e269-70, 2015. (Keyword) Aged / Colitis, Ulcerative / Humans / Male / Pyoderma Gangrenosum / Scleritis (Link to Publication Site) ● Publication site (DOI): 10.1111/ijd.12791 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 25784378 ● Search Scopus @ Elsevier (PMID): 25784378 ● Search Scopus @ Elsevier (DOI): 10.1111/ijd.12791 (DOI: 10.1111/ijd.12791, PubMed: 25784378)
32.	Yoshihiro Matsudate, Kazutoshi Murao and Yoshiaki Kubo : A case of sarcoidosis diagnosed by granulomatous tattoo reactions, Japanese Journal of Clinical Dermatology, Vol.69, No.2, 121-125, 2015. (Keyword) 刺青 / サルコイドーシス (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1390283684869498752 (CiNii: 1390283684869498752)
33.	Kazutoshi Murao, Rika Yoshioka and Yoshiaki Kubo : Human papillomavirus infection in Bowen disease: Negative p53 expression, not p16(INK4a) overexpression, is correlated with human papillomavirus-associated Bowen disease, The Journal of Dermatology, Vol.41, No.10, 878-884, 2014. (Summary) Genital Bowen disease (BD) has been linked to the high-risk types of human papillomavirus (HPV) infection. Recently, it has been recognized that HPV also can be associated with extragenital BD. HPV oncoproteins E6 and E7 interfere with the function of p53 and pRb, respectively, leading carcinogenesis. p16(INK4a) overexpression induced by inactivation of pRb is recognized as a surrogate marker for HPV-associated cervical cancer. In this study, we examined the presence of HPV DNA in 142 BD lesions by polymerase chain reaction (PCR), and determined the type of HPV by PCR restriction fragment length polymorphism or direct DNA sequencing. HPV DNA was detected in 66.7% of genital BD and 8.3% of extragenital BD. The types of HPV detected were HPV types 6, 16, 33, 52, 56, 58 and 59. We also investigated the expression of p16(INK4a) , pRb and p53 by immunohistochemistry. Positive expression was detected in 88.6% for p16(INK4a) , 25.2% for pRb, and 63.8% for p53. There was no significant difference in p16(INK4a) and pRb expression between HPV-positive and -negative BD. However, a strong correlation of HPV positivity with p53 negativity was found. A total of 66.7% of HPV-positive BD showed no p53 expression, whereas the corresponding rate was 32.8% of HPV-negative BD. This study demonstrated that HPV can participate in the development of BD, not only in the genital lesion, but also in extragenital lesion. p16(INK) (4a) overexpression is not a marker for HPV infection in BD. Instead, negative p53 expression is correlated with HPV-associated BD. (Link to Publication Site) ● Publication site (DOI): 10.1111/1346-8138.12613 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 25201325 ● Summary page in Scopus @ Elsevier: 2-s2.0-84908410065 (DOI: 10.1111/1346-8138.12613, PubMed: 25201325, Elsevier: Scopus)
34.	Mika Oshima, Kazutoshi Murao and Yoshiaki Kubo : エキセナチドの皮下注射部位に生じた薬疹の1例, Hifuka No Rinsho, Vol.56, No.9, 1374-1375, 2014.
35.	Mika Oshima, 祖川麻衣子, Sugita Takashi, Matsunaka Hiroshi, Murakami Yumi, Saya Yumiko, Yoshihiro Matsudate, Nozomi Fukui, Kazutoshi Murao and Yoshiaki Kubo : Improvement of Scalp Condition and Quality of Life through Proper Skin Care of Dry Scalp, Journal of Cosmetics Dermatological Sciences and Applications, Vol.4, No.4, 284-292, 2014. (Link to Publication Site) ● Publication site (DOI): 10.4236/jcdsa.2014.44038 (Link to Search Site for Scientific Articles) ● Search Scopus @ Elsevier (DOI): 10.4236/jcdsa.2014.44038 (DOI: 10.4236/jcdsa.2014.44038)
36.	仁木真理子, Yoshihiro Matsudate, Kazutoshi Murao, Yoshiaki Kubo, Ichiro Hashimoto, 柏木圭介, 仙崎雄一 and Hideki Nakanishi : リンパ節転移を伴った mucinous carcinoma of the skin の1例, 臨床皮膚科, Vol.68, No.9, 720-724, 2014.
37.	Mayu Yuasa, Takeshi Ishigami, Kazutoshi Murao, Yoshiaki Kubo, Yumiko Kotani and Hiroaki Kohno : A case of methylmalonic academia with acrodermatitis enteropathica-like eruption due to essential amino acids deficiency, Japanese Journal of Clinical Dermatology, Vol.68, No.7, 525-529, 2014. (Keyword) メチルマロン酸血症 / 腸性肢端皮膚炎様皮疹 / 必須アミノ酸欠乏 (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1390565159844814208 (CiNii: 1390565159844814208)
38.	Yoshihiro Matsudate, 仙崎聖子, Kazutoshi Murao, Yoshiaki Kubo and Yasutoshi Hida : A case of ichthyosiform mycosis fungoides, Japanese Journal of Clinical Dermatology, Vol.68, No.6, 453-457, 2014. (Keyword) 魚鱗癬様菌状息肉症 / 後天性魚鱗癬 / 毛包性丘疹 (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1390002209891348352 (CiNii: 1390002209891348352)
39.	Yutaro Yamashita, Ichiro Hashimoto, Yoshiro Abe, Takuya Seike, Katsumasa Okawa, Yuichi Senzaki, Kazutoshi Murao, Yoshiaki Kubo and Hideki Nakanishi : Effect of the Biopsy Technique on the Survival Rate of Malignant Melanoma Patients, Archives of Plastic Surgery, Vol.41, No.2, 122-125, 2014. (Summary) Cutaneous malignant melanoma has a poor prognosis. The detrimental effect of incisional biopsies on the outcome of malignant melanoma has been debated. The aim of this study was to determine the effect of the presence and type of biopsy on the prognosis of malignant melanoma. The medical records of 109 malignant melanoma patients treated at Tokushima University Hospital from 1983 to 2007 were reviewed. After excluding 28 cases with stage 0 disease or incomplete data, 81 cases were analyzed in detail with respect to patient sex, age, tumor site, clinical stage at diagnosis, presence of ulceration or lymph node metastasis, and prognosis. The five-year survival and five-year disease-free survival rates of patients who underwent incisional or excisional biopsies were compared with those who did not undergo a biopsy. The male-to-female ratio was 1:1.19. The mean age was 61.3 years (range, 19-93 years). The most common site was a lower extremity, and the most common clinical stage was stage II. No significant differences in clinicopathological features, five-year survival rates, and five-year disease-free survival rates were observed among the three groups. The presence and type of biopsy neither affected the metastatic rate nor the prognosis of malignant melanoma. The use of incisional biopsies is not encouraged because tumor thickness cannot be measured accurately. However, they may be helpful for confirming the diagnosis if an excisional biopsy cannot be performed. (Tokushima University Institutional Repository) ● Metadata: 114286 (Link to Publication Site) ● Publication site (DOI): 10.5999/aps.2014.41.2.122 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 24665419 ● Summary page in Scopus @ Elsevier: 2-s2.0-84896446893 (Tokushima University Institutional Repository: 114286, DOI: 10.5999/aps.2014.41.2.122, PubMed: 24665419, Elsevier: Scopus)
40.	Kazutoshi Murao, Osamu Miyajima and Yoshiaki Kubo : Woolly hair nevus associated with digital abnormalities and auditory disturbance., International Journal of Dermatology, Vol.53, No.3, e164-e166, 2014. (Keyword) Female / Fingers / Hair Diseases / Hand Deformities, Congenital / Hearing Disorders / Humans / Infant (Link to Publication Site) ● Publication site (DOI): 10.1111/j.1365-4632.2012.05819.x (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 23621149 ● Search Scopus @ Elsevier (PMID): 23621149 ● Search Scopus @ Elsevier (DOI): 10.1111/j.1365-4632.2012.05819.x (DOI: 10.1111/j.1365-4632.2012.05819.x, PubMed: 23621149)
41.	仙崎聖子, 仁木真理子, Kazutoshi Murao, Yoshiaki Kubo, Yoshihisa Sakao and 高橋収 : CASE REPORTS : Two Cases of Contact Dermatitis Due to Hair Dyes, Hifuka No Rinsho, Vol.56, No.3, 403-407, 2014. (Keyword) 接触皮膚炎 / ヘアダイ / 酸化染毛剤 / インディゴ (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1522825130424790528 (CiNii: 1522825130424790528)
42.	Yoshibumi Shimizu, Kazutoshi Murao, Tamotsu Tanaka, Yoshiaki Kubo and Akira Tokumura : Increased lysophospholipase D activity of autotaxin in sera of patients with atopic dermatitis., Journal of Dermatological Science, Vol.74, No.2, 162-165, 2014. (Link to Publication Site) ● Publication site (DOI): 10.1016/j.jdermsci.2014.01.010 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 24582488 ● Summary page in Scopus @ Elsevier: 2-s2.0-84897115979 (DOI: 10.1016/j.jdermsci.2014.01.010, PubMed: 24582488, Elsevier: Scopus)
43.	仁木真理子, Kazutoshi Murao, Tomoya Mizutani and Yoshiaki Kubo : Xanthomas Associated with Primary Biliary Cirrhosis, Hifuka No Rinsho, Vol.55, No.13, 1879-1882, 2013. (Keyword) 黄色腫 / 原発性胆汁性肝硬変 / 小結節型 / 手掌線条型 (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1521417755939321472 (CiNii: 1521417755939321472)
44.	横田綾, Kazutoshi Murao, 土田健司, 水口潤 and 川島周 : ナローバンドUVB療法が奏効した多発性尿毒症性痒疹の1例, 皮膚科の臨床, Vol.55, No.11, 1478-1479, 2013.
45.	Yoshihiro Matsudate, 仁木真理子, Kazutoshi Murao and Yoshiaki Kubo : A case of livedo vasculopathy successfully treated with dabigatran, Japanese Journal of Clinical Dermatology, Vol.67, No.10, 759-763, 2013. (Keyword) リベド血管症 / ダビガトラン / 脳出血 / 下腿潰瘍 (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1390565159845609344 (CiNii: 1390565159845609344)
46.	A Ruth White, M Jill Neiman, Anand Reddi, Gangwen Han, Stanca Birlea, Doyel Mitra, Laikuan Dionne, Pam Fernandez, Kazutoshi Murao, Li Bian, B Stephen Keysar, B Nathaniel Goldstein, Ningjing Song, Sophia Bornstein, Zheyi Han, Xian Lu, Joshua Wisell, Fulun Li, John Song, Shi-Long Lu, Antonio Jimeno, R Dennis Roop and Xiao-Jing Wang : Epithelial stem cell mutations that promote squamous cell carcinoma metastasis., The Journal of Clinical Investigation, Vol.123, No.10, 4390-4404, 2013. (Summary) Squamous cell carcinomas (SCCs) originate in stratified epithelia, with a small subset becoming metastatic. Epithelial stem cells are targets for driver mutations that give rise to SCCs, but it is unknown whether they contribute to oncogenic multipotency and metastasis. We developed a mouse model of SCC by targeting two frequent genetic mutations in human SCCs, oncogene Kras(G12D) activation and Smad4 deletion, to mouse keratin 15-expressing (K15+) stem cells. We show that transgenic mice developed multilineage tumors, including metastatic SCCs. Among cancer stem cell-enriched (CSC-enriched) populations, those with increased side population (SP) cells correlated with epithelial-mesenchymal transition (EMT) and lung metastasis. We show that microRNA-9 (miR-9) contributed to SP expansion and metastasis, and miR-9 inhibition reduced the number of SP cells and metastasis. Increased miR-9 was detected in metastatic human primary SCCs and SCC metastases, and miR-9-transduced human SCC cells exhibited increased invasion. We identified -catenin as a predominant miR-9 target. Increased miR-9 in human SCC metastases correlated with -catenin loss but not E-cadherin loss. Our results demonstrate that stem cells with Kras(G12D) activation and Smad4 depletion can produce tumors that are multipotent and susceptible to EMT and metastasis. Additionally, tumor initiation and metastatic properties of CSCs can be uncoupled, with miR-9 regulating the expansion of metastatic CSCs. (Keyword) Animals / Carcinogenesis / Carcinoma, Squamous Cell / Cell Dedifferentiation / Cell Proliferation / Epithelial-Mesenchymal Transition / Female / Gene Expression Regulation, Neoplastic / Humans / Mice / Mice, Nude / Mice, Transgenic / MicroRNAs / Mutation, Missense / Neoplasm Transplantation / Neoplastic Stem Cells / Proto-Oncogene Proteins / RNA Interference / Sequence Deletion / Side-Population Cells / Skin Neoplasms / Smad4 Protein / Tumor Cells, Cultured / alpha Catenin / ras Proteins (Link to Publication Site) ● Publication site (DOI): 10.1172/JCI65856 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 23999427 ● Summary page in Scopus @ Elsevier: 2-s2.0-84885064479 (DOI: 10.1172/JCI65856, PubMed: 23999427, Elsevier: Scopus)
47.	Takeshi Ishigami, Kazuhiro Furukita, Kazutoshi Murao and Yoshiaki Kubo : A Case of Leg Ulcers due to Juvenile-onset Deep Venous Thrombosis of the Leg Associated with Congenital Stenosis of the Inferior Vena Cava, The Nishinihon Journal of Dermatology, Vol.75, No.4, 301-303, 2013. (Link to Publication Site) ● Publication site (DOI): 10.2336/nishinihonhifu.75.301 (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1390282679278619520 ● Summary page in Scopus @ Elsevier: 2-s2.0-84888146242 (DOI: 10.2336/nishinihonhifu.75.301, CiNii: 1390282679278619520, Elsevier: Scopus)
48.	Mika Oshima, Yasutoshi Hida, 武市浩美, Kazutoshi Murao and Yoshiaki Kubo : Cutaneous Alternariosis on the Face Successfully Treated with a Combination of Terbinafine and Topical Heat Therapy, Hifuka No Rinsho, Vol.55, No.8, 982-985, 2013. (Keyword) アルテルナリア / 黒色真菌 / 局所温熱療法 (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1520573330552707200 (CiNii: 1520573330552707200)
49.	Kazutoshi Murao, Mayu Yuasa, Takeshi Ishigami, Yoshiaki Kubo and Seiji Arase : Bowen disease of the palm associated with human papillomavirus 52., Clinical and Experimental Dermatology, Vol.38, No.5, 489-491, 2013. (Summary) Human papillomavirus (HPV) is a well-known risk factor for many human cancers, especially cervical cancers. Among the nonmelanoma skin cancers, Bowen disease (BD) of the genitalia and fingers has also been shown to be closely associated with the high-risk types of HPV, especially HPV16. We report a case of BD of the palm, which is a very rare location for BD. In addition to its rare location, HPV52, which is classified as a mucous high-risk HPV type, was detected in the lesion by PCR restriction fragment length polymorphism analysis. To our knowledge, this is the first reported case of BD associated with HPV52. (Keyword) Aged / Bowen's Disease / Female / Hand Dermatoses / Humans / Papillomaviridae / Papillomavirus Infections / Rare Diseases / Skin Neoplasms (Link to Publication Site) ● Publication site (DOI): 10.1111/j.1365-2230.2012.04382.x (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 23659186 ● Search Scopus @ Elsevier (PMID): 23659186 ● Search Scopus @ Elsevier (DOI): 10.1111/j.1365-2230.2012.04382.x (DOI: 10.1111/j.1365-2230.2012.04382.x, PubMed: 23659186)
50.	Tomoya Mizutani, Natsuko Inoue, Kazutoshi Murao, Yoshiaki Kubo and Osamu Takahashi : Hypomelanosis of Ito: A Case of Definitive Diagnosis without any Extracutaneous Complication at First Medical Examination and a Case of Presumptive Diagnosis, Hifuka No Rinsho, Vol.55, No.5, 576-579, 2013.
51.	Osamu Miyajima, Kazutoshi Murao, Yoshiaki Kubo and Kyoko Takeuchi : B細胞リンパ腫に合併したbullous amyloidosis, 皮膚病診療, Vol.35, No.4, 387-390, 2013.
52.	Kazutoshi Murao, Yasushi Sadamoto, Yoshiaki Kubo and Seiji Arase : Generalized malignant acanthosis nigricans with "deck-chair sign"., International Journal of Dermatology, Vol.52, No.3, 377-378, 2013. (Keyword) Acanthosis Nigricans / Adenocarcinoma / Aged / Fatal Outcome / Female / Gastrectomy / Humans / Lymph Node Excision / Parapsoriasis / Splenectomy / Stomach Neoplasms (Link to Publication Site) ● Publication site (DOI): 10.1111/j.1365-4632.2011.04915.x (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 23414165 ● Summary page in Scopus @ Elsevier: 2-s2.0-84873975793 (DOI: 10.1111/j.1365-4632.2011.04915.x, PubMed: 23414165, Elsevier: Scopus)
53.	緋田哲也, Yoshihiro Matsudate, Kazutoshi Murao, Yoshiaki Kubo and Yasutoshi Hida : A case of Bowen's disease arising in a region of seborrheic keratosis, Skin Cancer, Vol.28, No.2, 181-184, 2013. (Summary) A 73-year-old Japanese woman was referred to our hospital because of a left leg skin tumor which was gradually growing. Clinical examination revealed a 14 × 13mm brownish keratotic plaque on her leg. Since an excisional biopsy specimen taken by a local dermatologist suggested squamous cell carcinoma, we performed an excisional biopsy. Histologically, the lesion consisted of proliferating keratinocytes. The periphery of the tumor showed reticulated seborrheic keratosis ; whereas in the center portion of the tumor, tumor cells consisted of atypical keratinocytes in the entire epidermis which was considered to be Bowen's disease. We should keep in mind that although rare, skin cancer, including Bowen's disease, could arise in a lesion of seborrheic keratosis.[Skin Cancer (Japan) 2013 ; 28 : 181-184] (Keyword) Seborrheic keratosis / Bowen's disease (Link to Publication Site) ● Publication site (DOI): 10.5227/skincancer.28.181 (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1390001204335187840 ● Search Scopus @ Elsevier (DOI): 10.5227/skincancer.28.181 (DOI: 10.5227/skincancer.28.181, CiNii: 1390001204335187840)
54.	Takeshi Ishigami, Yasutoshi Hida, Yoshihiro Matsudate, Kazutoshi Murao and Yoshiaki Kubo : The involvement of fibroblast growth factor receptor signaling pathways in dermatofibroma and dermatofibrosarcoma protuberans., The Journal of Medical Investigation : JMI, Vol.60, No.1-2, 106-113, 2013. (Summary) Fibroblast growth factors (FGFs) and their receptors (FGFRs) control a wide range of biological functions; however, their involvement in the pathogenesis of dermatofibroma (DF) and dermatofibrosarcoma protuberans (DFSP) is currently unknown. In this study, we first confirmed the histological diagnosis by detecting fusion COL1A1-PDGFB transcripts in DFSP, and examined the expression of all FGFRs (FGFR1-4), some of their ligands (FGF1, 2, 9), and forkhead box N1 (FOXN1) as a downstream target of FGFR3 in DF and DFSP by immunohistochemical analysis. Although we failed to detect the expression of FGF1 and FGF9 as specific ligands for FGFR3 in DF, overexpression of FGFR3 and FOXN1 was observed in the epidermal regions of DF, suggesting that the epidermal regions of DF were similar to seborrhoeic keratosis both in terms of histological features and the activation of FGFR3/FOXN1. In addition, strong expression of FGF2 and FGFR4 was observed in the tumor lesions of DF. Expression patterns of FGFR3/FOXN1 and FGF2/FGFR4 in DF were in contrast with those of DFSP. The activation of FGFR signaling pathways may be not only relevant to the pathogenesis of DF, but also very useful in the differential diagnosis of DF and DFSP. (Keyword) Adult / Aged / Collagen Type I / Dermatofibrosarcoma / Female / Forkhead Transcription Factors / Genes, sis / Histiocytoma, Benign Fibrous / Humans / Male / Middle Aged / Receptors, Fibroblast Growth Factor / Signal Transduction (Tokushima University Institutional Repository) ● Metadata: 106044 (Link to Publication Site) ● Publication site (DOI): 10.2152/jmi.60.106 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 23614918 ● Summary page in Scopus @ Elsevier: 2-s2.0-84876059149 (Tokushima University Institutional Repository: 106044, DOI: 10.2152/jmi.60.106, PubMed: 23614918, Elsevier: Scopus)
55.	Mika Oshima, Kazutoshi Murao, Takeshi Ishigami and Yoshiaki Kubo : Drug eruption induced by gonadotropin-releasing hormone analogs accompanying radiation-recall phenomenon., The Journal of Dermatology, Vol.39, No.12, 1080-1081, 2012. (Link to Publication Site) ● Publication site (DOI): 10.1111/j.1346-8138.2012.01576.x (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 22568476 ● Search Scopus @ Elsevier (PMID): 22568476 ● Search Scopus @ Elsevier (DOI): 10.1111/j.1346-8138.2012.01576.x (DOI: 10.1111/j.1346-8138.2012.01576.x, PubMed: 22568476)
56.	仙崎聖子, Kenji Hirose, Takeshi Ishigami, Kazutoshi Murao, Yoshiaki Kubo and Yasuhiko Nishioka : Two cases of photosensitive drug eruption due to pirfenidone, Japanese Journal of Clinical Dermatology, Vol.66, No.12, 945-948, 2012. (Keyword) ピルフェニドン / 光線過敏症 / 光毒性 (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1390283684869687680 (CiNii: 1390283684869687680)
57.	Tomoya Mizutani, Kazutoshi Murao and Yuki Miyaoka : A case of myoepithelioma of the sole, Japanese Journal of Clinical Dermatology, Vol.66, No.11, 875-878, 2012. (Keyword) 筋上皮腫 / myoepithelioma / 足底 (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1390565159846373376 (CiNii: 1390565159846373376)
58.	Hidetaka Tsuda, Akihiko Sakaki and Kazutoshi Murao : 巨大な潰瘍を形成した頭部血管肉腫, Hifuka No Rinsho, Vol.54, No.5, 653-654, 2012.
59.	Mika Oshima, Kazutoshi Murao and Seiji Arase : Drug-induced skin damage by intravenous administration of Nifekalant hydrochloride, Hifuka No Rinsho, Vol.54, No.1, 55-57, 2012. (Keyword) 塩酸ニフェカラント / 皮下硬結 (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1521699230837597440 (CiNii: 1521699230837597440)
60.	Kazutoshi Murao, Daisuke Fukumoto and Yoshiaki Kubo : Squamous cell carcinoma of the scalp associated with human papillomavirus type 16., European Journal of Dermatology : EJD, Vol.21, No.6, 1005-1006, 2011. (Keyword) Aged, 80 and over / DNA, Viral / Female / Head and Neck Neoplasms / Human papillomavirus 16 / Humans / Immunohistochemistry / Papillomavirus Infections / Polymerase Chain Reaction / Scalp / Skin Diseases (Link to Publication Site) ● Publication site (DOI): 10.1684/ejd.2011.1520 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 21896422 ● Search Scopus @ Elsevier (PMID): 21896422 ● Search Scopus @ Elsevier (DOI): 10.1684/ejd.2011.1520 (DOI: 10.1684/ejd.2011.1520, PubMed: 21896422)
61.	Kazutoshi Murao, Yasutoshi Hida, Mayumi Minato, Yoshiaki Kubo and Seiji Arase : Relapsing polychondritis associated with psoriasis vulgaris and alopecia areata., European Journal of Dermatology : EJD, Vol.21, No.5, 779-780, 2011. (Keyword) Adult / Alopecia Areata / Autoimmune Diseases / Female / Humans / Polychondritis, Relapsing / Psoriasis (Link to Publication Site) ● Publication site (DOI): 10.1684/ejd.2011.1437 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 21697067 ● Search Scopus @ Elsevier (PMID): 21697067 ● Search Scopus @ Elsevier (DOI): 10.1684/ejd.2011.1437 (DOI: 10.1684/ejd.2011.1437, PubMed: 21697067)
62.	Yoshiaki Kubo, Yoshio Urano, Rie Matsuda, Takeshi Ishigami, Kazutoshi Murao, Seiji Arase and Akemi Ishida-Yamamoto : Ichthyosis hystrix, Curth-Macklin type: a new sporadic case with a novel mutation of keratin 1., Archives of Dermatology, Vol.147, No.8, 999-1001, 2011. (Keyword) Child, Preschool / Dermatitis, Seborrheic / Humans / Ichthyosis / Keratin-1 / Male / Mutation (Link to Publication Site) ● Publication site (DOI): 10.1001/archdermatol.2011.217 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 21844476 ● Search Scopus @ Elsevier (PMID): 21844476 ● Search Scopus @ Elsevier (DOI): 10.1001/archdermatol.2011.217 (DOI: 10.1001/archdermatol.2011.217, PubMed: 21844476)
63.	M Fukumoto, Kazutoshi Murao, Hiroyoshi Watanabe, Yoshiaki Kubo and Seiji Arase : Generalized hypopigmented macules after bone-marrow transplantation., Clinical and Experimental Dermatology, Vol.36, No.7, 803-804, 2011. (Keyword) Bone Marrow Transplantation / Child / Humans / Hypopigmentation / Male / Melanocytes / Postoperative Complications (Link to Publication Site) ● Publication site (DOI): 10.1111/j.1365-2230.2011.04044.x (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 21575040 ● Search Scopus @ Elsevier (PMID): 21575040 ● Search Scopus @ Elsevier (DOI): 10.1111/j.1365-2230.2011.04044.x (DOI: 10.1111/j.1365-2230.2011.04044.x, PubMed: 21575040)
64.	Tamara Terzian, Enrique C. Torchia, Daisy Dai, Steven E. Robinson, Kazutoshi Murao, Victoria Gonzalez, Regan A. Stiegmann, Glen M. Boyle, Marianne B. Powell, Pamela M. Pollock, Guillermina Lozano, William A. Robinson, Dennis R. Roop and Neil F. Box : p53 prevents progression of nevi to melanoma predominantly through cell cycle regulation, Pigment Cell & Melanoma Research, Vol.23, No.6, 781-794, 2010. (Summary) p53 is the central member of a critical tumor suppressor pathway in virtually all tumor types, where it is silenced mainly by missense mutations. In melanoma, p53 predominantly remains wild type, thus its role has been neglected. To study the effect of p53 on melanocyte function and melanomagenesis, we crossed the `high-p53'Mdm4+/- mouse to the well-established TP-ras0/+ murine melanoma progression model. After treatment with the carcinogen dimethylbenzanthracene (DMBA), TP-ras0/+ mice on the Mdm4+/- background developed fewer tumors with a delay in the age of onset of melanomas compared to TP-ras0/+ mice. Furthermore, we observed a dramatic decrease in tumor growth, lack of metastasis with increased survival of TP-ras0/+: Mdm4+/- mice. Thus, p53 effectively prevented the conversion of small benign tumors to malignant and metastatic melanoma. p53 activation in cultured primary melanocyte and melanoma cell lines using Nutlin-3, a specific Mdm2 antagonist, supported these findings. Moreover, global gene expression and network analysis of Nutlin-3-treated primary human melanocytes indicated that cell cycle regulation through the p21WAF1/CIP1 signaling network may be the key anti-melanomagenic activity of p53. (Link to Publication Site) ● Publication site (DOI): 10.1111/j.1755-148X.2010.00773.x (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 20849464 ● Search Scopus @ Elsevier (PMID): 20849464 ● Search Scopus @ Elsevier (DOI): 10.1111/j.1755-148X.2010.00773.x (DOI: 10.1111/j.1755-148X.2010.00773.x, PubMed: 20849464)
65.	Sachiko Takeichi, Yoshiaki Kubo, Kazutoshi Murao, Natsuko Inoue, Shin-ichi Ansai and Seiji Arase : Coexistence of giant blue nevus of the scalp with hair loss and alopecia areata., The Journal of Dermatology, Vol.38, No.4, 377-381, 2010. (Summary) A 43-year-old Japanese man presented with a 13-year history of a grayish macule measuring 7 cm in diameter with sparse hairs on the vertex. Histopathological examination demonstrated two types of melanocytes, spindle-shaped and ovoid cells, with abundant melanin aggregated around the upper part of the pilosebaceous apparatus. Fibrous, thick collagen bundles were also seen surrounding the upper part of the small hair follicles. There was no infiltration of melanocytes or lymphocytes in the lower dermis or adipose tissue. Based on these findings, a diagnosis of blue nevus, cellular type, was made. Giant cellular blue nevi on the scalp are rare, and 11 cases reported in the published work have shown characteristic features such as hair loss and cranial invasion of nevus cells. It should be noted that melanocytes of giant blue nevi have a high potential to damage other organs such as underlying bone and hair follicles. The patient also showed a typical lesion of alopecia areata on the left temporal which was successfully treated with topical corticosteroid. (Keyword) Adult / Alopecia Areata / Humans / Male / Nevus, Blue / Scalp / Skin Neoplasms / Tomography, X-Ray Computed (Link to Publication Site) ● Publication site (DOI): 10.1111/j.1346-8138.2010.01020.x (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 21352287 ● Search Scopus @ Elsevier (PMID): 21352287 ● Search Scopus @ Elsevier (DOI): 10.1111/j.1346-8138.2010.01020.x (DOI: 10.1111/j.1346-8138.2010.01020.x, PubMed: 21352287)
66.	Kazuya Matsumoto, Ichiro Hashimoto, Shinji Matsuo, Hideki Nakanishi, Yoshiaki Kubo, Kazutoshi Murao and Seiji Arase : Prevention of pressure ulcers in home care patients, Shikoku Acta Medica, Vol.65, No.5.6, 137-140, 2009. (Summary) A large proportion of home care patients are at risk of pressure ulcer. The occurrence rate of pressure ulcer is higher in home care patients than that in the patients of hospitals and welfare facilities. The home care patients need long-term conservative treatment because of the depth of the pressure ulcers.Treatment of the pressure ulcers at home results in increase of caregivers burden. Therefore,prevention and early detection of pressure ulcers are important in home nursing. In early stage of pressure ulcers，``deep tissue injury''should be taken into consideration because of its progressive nature. It is a new concept which presents deep tissue damage remaining superficial skin intact.One of clinical features in this condition is induration in a deep layer.The past decade has seen a huge growth in the application of pressure relieving mattresses,absorbent products for urinary and faecal incontinence, and skin barrier products to prevention of the pressure ulcers. Economical, physical, and psychological burden of nursing at home should be decreased with an accumulation of these information and utilization of the products. Therefore, it is important for caregivers to consult with their care managers and acquire new knowledge and information. (Keyword) pressure sore / skin care / deep tissue injury / caregivers (Tokushima University Institutional Repository) ● Metadata: 110292 (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1050845762395225344 (Tokushima University Institutional Repository: 110292, CiNii: 1050845762395225344)
67.	Yoshiaki Kubo, Kazutoshi Murao, Kazuya Matsumoto and Seiji Arase : Molecular carcinogenesis of squamous cell carcinomas of the skin., The Journal of Medical Investigation : JMI, Vol.49, No.3-4, 111-117, 2002. (Summary) Squamous cell carcinomas (SCCs) of the skin were suggested to develop through a multistep process that involves activation of proto-oncogenes and/or inactivation of tumor suppressor genes in the human skin keratinocytes. Exposure to ultra-violet (UV), especially UV-B, radiation is the most common cause for these genetic abnormalities in cells. We review causation of SCCs and genetic abnormalities in human SCCs with the current work. To elucidate the multistep process, we developed a method for examining the combinatorial function in vivo of plural genes in human keratinocytes. Using high efficiency retroviral transductions, we could express plural genes serially in normal human primary keratinocytes and use these cells to regenerate human skin on SCID mice. A combinatorial transduction of H-RasV12 and cyclin dependent kinase 4 (CDK4) produced human epidermal neoplasia resembling SCC. These findings were consistent with our previous results of mutation analysis in SCCs, one of which had both mutations of H-Ras gene and the INK4a locus. Therefore, it is suggested that a combination of these genetic abnormalities might be crucial to the carcinogenesis at least in a subset of SCCs. (Keyword) Animals / Carcinoma, Squamous Cell / Cell Cycle Proteins / Cell Transformation, Neoplastic / DNA Damage / DNA Repair / Gene Expression Regulation, Neoplastic / Genes, p16 / Genes, p53 / Genes, ras / Humans / Keratinocytes / Loss of Heterozygosity / Mice / Mice, SCID / Neoplasms, Radiation-Induced / Skin Neoplasms / Ultraviolet Rays (Tokushima University Institutional Repository) ● Metadata: 110643 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 12322999 ● Search Scopus @ Elsevier (PMID): 12322999 (Tokushima University Institutional Repository: 110643, PubMed: 12322999)
68.	Yasutoshi Hida, 浦野芳夫, Yoshiaki Kubo, 南満芳, 村尾牧子, 津田英隆, Kazutoshi Murao, 高野浩章, Seiji Arase and 長江浩朗 : 足底に難治性潰瘍を伴ったWerner症候群の3例, 臨床皮膚科, Vol.56, No.7, 487-491, 2002. (Keyword) Werner症候群 / WRN遺伝子 / 足底潰瘍

Academic Paper (Unrefereed Paper):

1.	Yoshiaki Kubo, Takeshi Ishigami and Kazutoshi Murao : リップクリーム中のミツロウによる接触皮膚炎, 皮膚病診療, Vol.33, No.7, 703-706, 2011.

Academic Letter:

1.	Kazutoshi Murao and Yoshiaki Kubo : Multiple Bowen disease lesions with the eyeliner sign in a psoriasis patient after long-term narrow-band ultraviolet B light therapy., The American Journal of Dermatopathology, Vol.46, No.3, 193-194, 2024. (Keyword) Humans / Bowen's Disease / Psoriasis / Skin Neoplasms / Treatment Outcome / Ultraviolet Therapy (Link to Publication Site) ● Publication site (DOI): 10.1097/DAD.0000000000002634 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 38275222 ● Summary page in Scopus @ Elsevier: 2-s2.0-85185221624 (DOI: 10.1097/DAD.0000000000002634, PubMed: 38275222, Elsevier: Scopus)
2.	Kazutoshi Murao and Yoshiaki Kubo : A case of childhood granulomatous periorificial dermatitis mimicking lichen nitidus, International Journal of Dermatology, Vol.62, No.3, e133-e135, 2023. (Keyword) Humans / Lichen Nitidus / Dermatitis, Perioral / Eczema / Exanthema / Pruritus (Link to Publication Site) ● Publication site (DOI): 10.1111/ijd.16270 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 35569093 ● Summary page in Scopus @ Elsevier: 2-s2.0-85132614935 (DOI: 10.1111/ijd.16270, PubMed: 35569093, Elsevier: Scopus)
3.	Kazutoshi Murao, Maiko Sogawa and Yoshiaki Kubo : A case of an insect bite-like reaction in a patient with angioimmunoblastic T-cell lymphoma., European Journal of Dermatology : EJD, Vol.29, No.4, 425-426, 2019. (Keyword) Aged / Female / Humans / Immunoblastic Lymphadenopathy / Insect Bites and Stings / Lymphoma, T-Cell, Cutaneous / Skin Neoplasms (Link to Publication Site) ● Publication site (DOI): 10.1684/ejd.2019.3571 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 31456577 ● Search Scopus @ Elsevier (PMID): 31456577 ● Search Scopus @ Elsevier (DOI): 10.1684/ejd.2019.3571 (DOI: 10.1684/ejd.2019.3571, PubMed: 31456577)
4.	Nozomi Fukui, Kazutoshi Murao, Maiko Sogawa and Yoshiaki Kubo : Case of papular acantholytic dyskeratosis of the genital area successfully treated with topical vitamin D3 ointment, The Journal of Dermatology, Vol.44, No.5, 599-560, 2017. (Link to Publication Site) ● Publication site (DOI): 10.1111/1346-8138.13488 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 27334529 ● Search Scopus @ Elsevier (PMID): 27334529 ● Search Scopus @ Elsevier (DOI): 10.1111/1346-8138.13488 (DOI: 10.1111/1346-8138.13488, PubMed: 27334529)
5.	Yoshihiro Matsudate, Kazutoshi Murao and Yoshiaki Kubo : Chemotherapy-induced inflammation of seborrheic keratoses due to pemetrexed treatment, The Journal of Dermatology, Vol.44, No.5, 602-603, 2017. (Link to Publication Site) ● Publication site (DOI): 10.1111/1346-8138.13499 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 27345694 ● Search Scopus @ Elsevier (PMID): 27345694 ● Search Scopus @ Elsevier (DOI): 10.1111/1346-8138.13499 (DOI: 10.1111/1346-8138.13499, PubMed: 27345694)
6.	Kazutoshi Murao, Ayaka Nakasuka, Tsuyoshi Keyama, Ichiro Hashimoto and Yoshiaki Kubo : Case of multiple Bowen diseases associated with human papillomavirus type 16 in a patient with atopic dermatitis., The Journal of Dermatology, Vol.43, No.4, 445-447, 2016. (Keyword) Administration, Cutaneous / Bowen's Disease / Dermatitis, Atopic / Glucocorticoids / Human papillomavirus 16 / Humans / Male / Middle Aged / Neck / Ointments / Papillomavirus Infections / Polymerase Chain Reaction / Skin Neoplasms (Link to Publication Site) ● Publication site (DOI): 10.1111/1346-8138.13216 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 26662565 ● Summary page in Scopus @ Elsevier: 2-s2.0-84949883866 (DOI: 10.1111/1346-8138.13216, PubMed: 26662565, Elsevier: Scopus)
7.	Yoshihiro Matsudate, Mayu Yuasa, Nozomi Fukui, Kenji Hirose, Kazutoshi Murao and Yoshiaki Kubo : Case of nevoid basal cell carcinoma syndrome with multiple cutaneous keratocysts., The Journal of Dermatology, Vol.42, No.10, 1015-1016, 2015. (Link to Publication Site) ● Publication site (DOI): 10.1111/1346-8138.13022 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 26126618 ● Search Scopus @ Elsevier (PMID): 26126618 ● Search Scopus @ Elsevier (DOI): 10.1111/1346-8138.13022 (DOI: 10.1111/1346-8138.13022, PubMed: 26126618)
8.	Yoshihiro Matsudate, Kazutoshi Murao and Yoshiaki Kubo : Primary cutaneous mucormycosis caused by Mucor irregularis in an immunocompetent patient, The Journal of Dermatology, Vol.42, No.3, 267-268, 2015. (Link to Publication Site) ● Publication site (DOI): 10.1111/1346-8138.12788 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 25736319 ● Summary page in Scopus @ Elsevier: 2-s2.0-84924033151 (DOI: 10.1111/1346-8138.12788, PubMed: 25736319, Elsevier: Scopus)
9.	Kazutoshi Murao, Yoshiaki Kubo and Seiji Arase : Woolly hair nevus: neonatal alopecia can be an initial manifestation., International Journal of Dermatology, Vol.52, No.12, 1588-1589, 2013. (Link to Publication Site) ● Publication site (DOI): 10.1111/j.1365-4632.2011.05420.x (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 24261737 ● Search Scopus @ Elsevier (PMID): 24261737 ● Search Scopus @ Elsevier (DOI): 10.1111/j.1365-4632.2011.05420.x (DOI: 10.1111/j.1365-4632.2011.05420.x, PubMed: 24261737)
10.	Kazutoshi Murao, Mayumi Minato and Yoshiaki Kubo : Improvement of palmoplantar pustulosis lesions after angioplasty for Leriche syndrome., The Australasian Journal of Dermatology, Vol.54, No.3, e80-81, 2013. (Summary) Although a wide range of treatments have been used in the treatment of palmoplantar pustulosis (PPP), PPP is still very difficult to treat. We report a patient who had a dramatic reduction in PPP lesions after bypass surgery for Leriche syndrome. We assume that improved blood circulation had a crucial impact in reducing PPP lesions and suggest improving blood circulation could be another treatment option. (Keyword) Angioplasty / Aorta, Abdominal / Diabetes Mellitus / Female / Foot Dermatoses / Humans / Iliac Artery / Leriche Syndrome / Lower Extremity / Middle Aged / Psoriasis / Severity of Illness Index / Vascular Grafting (Link to Publication Site) ● Publication site (DOI): 10.1111/j.1440-0960.2012.00940.x (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 22943836 ● Search Scopus @ Elsevier (PMID): 22943836 ● Search Scopus @ Elsevier (DOI): 10.1111/j.1440-0960.2012.00940.x (DOI: 10.1111/j.1440-0960.2012.00940.x, PubMed: 22943836)
11.	Kazutoshi Murao and Yoshiaki Kubo : A case of lichen planus significantly improved after topical heparinoid treatment, The Australasian Journal of Dermatology, Vol.54, No.3, 236-237, 2013. (Keyword) Administration, Cutaneous / Aged, 80 and over / Anti-Inflammatory Agents / Female / Heparinoids / Humans / Lichen Planus (Link to Publication Site) ● Publication site (DOI): 10.1111/ajd.12080 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 23905977 ● Search Scopus @ Elsevier (PMID): 23905977 ● Search Scopus @ Elsevier (DOI): 10.1111/ajd.12080 (DOI: 10.1111/ajd.12080, PubMed: 23905977)
12.	Kazutoshi Murao and Yoshiaki Kubo : Multiple epidermal cysts in hemodialysis patients, European Journal of Dermatology : EJD, Vol.22, No.2, 264-265, 2012. (Keyword) Adult / Cysts / Humans / Kidney Failure, Chronic / Male / Middle Aged / Renal Dialysis / Skin Diseases (Link to Publication Site) ● Publication site (DOI): 10.1684/ejd.2011.1626 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 22240490 ● Search Scopus @ Elsevier (PMID): 22240490 ● Search Scopus @ Elsevier (DOI): 10.1684/ejd.2011.1626 (DOI: 10.1684/ejd.2011.1626, PubMed: 22240490)
13.	Kazutoshi Murao, Mika Oshima, Osamu Miyajima and Yoshiaki Kubo : Verrucous skin lesions on the feet in diabetic neuropathy successfully treated with topical maxacalcitol, European Journal of Dermatology : EJD, Vol.22, No.2, 274-275, 2012. (Keyword) Adult / Calcitriol / Dermatologic Agents / Diabetes Mellitus, Type 2 / Diabetic Foot / Diabetic Neuropathies / Foot Dermatoses / Friction / Humans / Male / Pressure (Link to Publication Site) ● Publication site (DOI): 10.1684/ejd.2012.1640 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 22236391 ● Search Scopus @ Elsevier (PMID): 22236391 ● Search Scopus @ Elsevier (DOI): 10.1684/ejd.2012.1640 (DOI: 10.1684/ejd.2012.1640, PubMed: 22236391)
14.	Kazutoshi Murao, Yoshiaki Kubo and Seiji Arase : Verrucous extramammary Pagets disease accompanying human papillomavirus 40-associated condyloma acuminatum: importance of multiple skin biopsies, European Journal of Dermatology : EJD, Vol.21, No.2, 297-298, 2011. (Keyword) Aged / Biopsy / Carcinoma, Verrucous / Condylomata Acuminata / Genital Neoplasms, Male / Humans / Immunohistochemistry / Male / Paget Disease, Extramammary / Papillomavirus Infections / Skin (Link to Publication Site) ● Publication site (DOI): 10.1684/ejd.2011.1260 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 21398204 ● Search Scopus @ Elsevier (PMID): 21398204 ● Search Scopus @ Elsevier (DOI): 10.1684/ejd.2011.1260 (DOI: 10.1684/ejd.2011.1260, PubMed: 21398204)
15.	Kazutoshi Murao, Hiromi Takeichi, Yoshiaki Kubo and Seiji Arase : Multiple pilosebaceous cysts induced by topical steroid therapy, European Journal of Dermatology : EJD, Vol.20, No.6, 815-816, 2010. (Keyword) Administration, Topical / Adrenal Cortex Hormones / Aged / Cysts / Humans / Male / Sebaceous Glands / Skin Diseases (Link to Publication Site) ● Publication site (DOI): 10.1684/ejd.2010.1056 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 20822973 ● Search Scopus @ Elsevier (PMID): 20822973 ● Search Scopus @ Elsevier (DOI): 10.1684/ejd.2010.1056 (DOI: 10.1684/ejd.2010.1056, PubMed: 20822973)
16.	Kazutoshi Murao, Yoshiaki Kubo, Takeshi Ishigami and Seiji Arase : Lack of association between extramammary Pagets disease and human papillomavirus infection, Journal of Dermatological Science, Vol.59, No.3, 209-210, 2010. (Keyword) Aged / Aged, 80 and over / Female / Humans / Male / Paget Disease, Extramammary / Papillomavirus Infections / Skin Neoplasms (Link to Publication Site) ● Publication site (DOI): 10.1016/j.jdermsci.2010.07.002 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 20685084 ● Search Scopus @ Elsevier (PMID): 20685084 ● Search Scopus @ Elsevier (DOI): 10.1016/j.jdermsci.2010.07.002 (DOI: 10.1016/j.jdermsci.2010.07.002, PubMed: 20685084)

Review, Commentary:

1.	Kazutoshi Murao : British association of dermatologists' guidelines for the management of cutaneous warts, Japanese Journal of Clinical Dermatology, Vol.70, No.5, 155-157, Apr. 2016. (Link to Publication Site) ● Publication site (DOI): 10.11477/mf.1412204766 (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1390565159846674304 ● Search Scopus @ Elsevier (DOI): 10.11477/mf.1412204766 (DOI: 10.11477/mf.1412204766, CiNii: 1390565159846674304)
2.	Yoshiaki Kubo, Yoshihiro Matsudate, Nozomi Fukui, Ayaka Nakasuka, Maiko Sogawa, Mika Oshima, Tomoya Mizutani, Masanobu Otsu, Kazutoshi Murao and Ichiro Hashimoto : Molecular tumorigenesis of the skin., The Journal of Medical Investigation : JMI, Vol.61, No.1-2, 7-14, Feb. 2014. (Summary) Skin tumors are supposed to develop through accumulations of genetic and/or epigenetic events in normal cells of the skin. Among them, we focus on common skin tumors, including benign, seborrheic keratosis, and malignant, squamous cell carcinoma and melanoma. Many important molecules have been detected on the molecular tumorigenesis of each of them to date, and some drugs targeted for their molecules have been already developed. We review updates on the molecular tumorigenesis of these tumors with our current works. (Tokushima University Institutional Repository) ● Metadata: 109490 (Link to Publication Site) ● Publication site (DOI): 10.2152/jmi.61.7 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 24705742 ● Summary page in Scopus @ Elsevier: 2-s2.0-84897947733 (Tokushima University Institutional Repository: 109490, DOI: 10.2152/jmi.61.7, PubMed: 24705742, Elsevier: Scopus)
3.	Kazutoshi Murao : 菌状息肉症の亜型, 日本臨床, Vol.71, No.4, 782-785, 2013.

Proceeding of International Conference:

1.	Kazutoshi Murao and Yoshiaki Kubo : The development of Bowen disease is driven by podoplanin positive cells which can be inhibited by ROCK inhibitor., 1st international societies for investigative dermatology meeting, May 2023.
2.	Kazutoshi Murao, H Takeichi, Yoshiaki Kubo and Seiji Arase : Multiple pilocebaseouc systs induced by topical steroid therapy, The 1st Eastern Asia Dermatology Congress, Sep. 2010.
3.	BI Kubick, Kazutoshi Murao and DR Roop : Identification of rare skin cancer stem cells using a syngeneic mouse model, The70th Annual Meeting of the Society for Investigative Dermatology, May 2010.

Proceeding of Domestic Conference:

1.	Hiroyoshi Watanabe, 田中真波, 福良翔子, 佐藤宏紀, 戸梶成美, Kazutoshi Murao and 吉野正 : 皮下脂肪織炎様T細胞リンパ腫(SPTCL)様T細胞リンパ腫(γδ phenotype)の幼児例, 第63回日本小児血液・がん学会学術集会, Nov. 2021.
2.	山崎佳那子, 祖川麻衣子, Kazutoshi Murao, Yoshiaki Kubo, Masahiro Oura, Takeshi Harada, Shingen Nakamura and Kumiko Kagawa : 骨髄異形成症候群の患者に生じた晩発性皮膚ポルフィリン症の1例, The Nishinihon Journal of Dermatology, Vol.82, No.3, 238-239, Jun. 2020. (Keyword) 骨髄異形成症候群(合併症) Uroporphyrins(尿) ポルフィリン症-晩発性皮膚(合併症,診断) ヒト中年(45~64) 男
3.	Yoshiaki Kubo, Yoshihiro Matsudate and Kazutoshi Murao : Cowden症候群の皮膚粘膜病変, 第5回消化管ポリポーシス研究会, Jan. 2019.
4.	Mariko Niki, Ayaka Nakasuka, 祖川麻衣子 and Kazutoshi Murao : 顔面に生じたlinear cutaneous lupus erythematosusの1例, 第150回日本皮膚科学会徳島地方会, Nov. 2018.
5.	Yoshihiro Matsudate, Kazutoshi Murao, Yoshiaki Kubo and 高橋収 : 除草剤ラッソーによる化学熱傷後に生じた多形紅斑の1例, 第47回日本皮膚アレルギー・接触皮膚炎学会総会学術大会, Dec. 2017.
6.	Kazutoshi Murao : 皮膚有棘細胞癌, 日本皮膚科学会第69回西部支部総会, Oct. 2017.
7.	Kanako Yamasaki, Chiaki Miyamoto, Mio Yada, Yoshihiro Matsudate, Kazutoshi Murao, Yoshiaki Kubo and Taichi Murakami : 急速に腎障害が進行したクリオグロブリン血症性血管炎の1例, 第69回日本皮膚科学会西部支部学術大会, Oct. 2017.
8.	Mayu Yuasa, Kazutoshi Murao and Yoshiaki Kubo : ニボルマブ投与中に中枢性副腎機能不全を生じた悪性黒色腫の1例, 日本皮膚悪性腫瘍学会, Jul. 2017.
9.	Masanobu Ootsu, Kazutoshi Murao, Ken-ichi Suga, Ryuji Nakagawa, Shoji Kagami, Issei Imoto and Yoshiaki Kubo : ADAM17欠損症を疑った1例, 第116回日本皮膚科学会総会, Jun. 2017.
10.	Mio Yada, Kanako Yamasaki, Kazutoshi Murao, Yoshiaki Kubo, Yuta Arai and Seiji Iwamoto : 日本紅斑熱患者に発症した特発性腸腰筋血腫の1例, 第116回日本皮膚科学会総会, Jun. 2017.
11.	Yoshihiro Matsudate, 山﨑佳那子, Kazutoshi Murao and Yoshiaki Kubo : ラミニンγ1に対する自己抗体も有した線状IgA/IgG水疱性皮膚症の1例, 第116回日本皮膚科学会総会, Jun. 2017.
12.	Maiko Iwasaka, Hirokazu Agawa, Mio Yada and Kazutoshi Murao : Eruptive neviの1例, 第147回日本皮膚科学会徳島地方会, May 2017.
13.	Tetsuya Hida, Kenji Hirose, Kazutoshi Murao, Hirokazu Takechi, 氏家英之 and Yoshiaki Kubo : 乳癌を合併した後天性表皮水疱症の1例, 第79回日本皮膚科学会沖縄地方会, Jan. 2017.
14.	水谷育宏, Masanobu Ootsu, Tetsuya Hida and Kazutoshi Murao : 結節性類天疱瘡の1例, 第146回日本皮膚科学会徳島地方会, Dec. 2016.
15.	Yoshihiro Matsudate, Kazutoshi Murao, 浦野芳夫 and Yoshiaki Kubo : 点滴留置針外套による接触皮膚炎の3例, 第46回日本皮膚アレルギー・接触皮膚炎学会総会学術大会, Nov. 2016.
16.	Kazutoshi Murao : アトピー性皮膚炎の最近の話題, 東四国医療セミナー, Oct. 2016.
17.	宮本千暁, Mio Yada, Yoshihiro Matsudate, Kazutoshi Murao and Yoshiaki Kubo : アザチオプリンによる急性汎発性発疹性膿疱症の1例, Jun. 2016.
18.	Yoshihiro Matsudate, Kazutoshi Murao and Yoshiaki Kubo : 偽癌性増殖を伴った原発性皮膚CD30陽性リンパ増殖症の1例, 第115回日本皮膚科学会総会, Jun. 2016.
19.	Mio Yada, Kenji Hirose, Kazutoshi Murao, Yoshiaki Kubo, Kazuhide Mineda, Ichiro Hashimoto and Shin-ichi Ansai : 鼻尖部に生じた脂腺癌の1例, 第32回日本皮膚悪性腫瘍学会学術大会, May 2016.
20.	Mayu Yuasa, Kazutoshi Murao and Yoshiaki Kubo : 上肢のBlaschko線に沿って生じた硬化性苔癬の一例, 日本皮膚科学会, May 2016. (Keyword) 硬化性苔癬
21.	Mio Yada, Kenji Hirose, Kazutoshi Murao, Yoshiaki Kubo, Kazuhide Mineda, Ichiro Hashimoto and Shin-ichi Ansai : 鼻尖部に生じた脂腺癌の1例, 第169回日本皮膚科学会山口地方会, Mar. 2016.
22.	Mayu Yuasa and Kazutoshi Murao : 躯幹にも皮疹を生じたannular elastolytic giant cell granulomaの1例, 日本皮膚科学会第76回沖縄地方会, Feb. 2016. (Keyword) annular elastolytic giant cell granuloma
23.	Yoshihiro Matsudate, Kazutoshi Murao, Yoshiaki Kubo and Issei Imoto : Genetic diagnosis of the nevoid basal cell carcinoma syndrome using next-generation sequencer, 第40回日本研究皮膚科学会, Dec. 2015.
24.	Yoshihiro Matsudate, Kazutoshi Murao and Yoshiaki Kubo : 後天性リンパ管腫を契機に診断に至ったCowden病の1家系, 第114回日本皮膚科学会総会, May 2015.
25.	Yoshihiro Matsudate, Kazutoshi Murao and Yoshiaki Kubo : ミドリンPとヒアレインミニ点眼液による接触皮膚炎の1例, 第44回日本皮膚アレルギー・接触皮膚炎学会学術大会, Nov. 2014.
26.	Yoshihiro Matsudate, Kazutoshi Murao and Yoshiaki Kubo : ペメトレキセド投与により脂漏性角化症，アクロコルドンに限局して紅斑を生じた2例, 第66回日本皮膚科学会西部支部学術大会, Nov. 2014.
27.	Kazutoshi Murao and Yoshiaki Kubo : 静脈怒張部に一致して白斑を生じた尋常性白斑の2例, 第128回山陰・第24回島根合同開催地方会, Aug. 2014.
28.	Tomoya Mizutani, 木下華子, Rie Yamamura and Kazutoshi Murao : 多発性神経鞘腫を生じた神経線維腫症2型の1例, 第141回日本皮膚科学会徳島地方会, Jun. 2014.
29.	祖川麻衣子, Yoshihiro Matsudate, Kazutoshi Murao, Yoshiaki Kubo and Mika Sakaki : Primary cutaneous follicle center lymphomaの1例, 第113回日本皮膚科学会総会, May 2014.
30.	Yoshihiro Matsudate, Kazutoshi Murao and Yoshiaki Kubo : 多数のcutaneous keratocystsを伴った母斑性基底細胞癌症候群の1例, 第113回日本皮膚科学会総会, May 2014.
31.	Kazutoshi Murao, 中須賀彩香 and Yoshiaki Kubo : アトピー性皮膚炎患者に生じ，HPV16が検出された多発性Bowen病の1例, 第368回日本皮膚科学会福岡地方会, Mar. 2014.
32.	Kazutoshi Murao, 祖川麻衣子 and Yoshiaki Kubo : HPV16を検出した足背部Bowen病の1例, 第137回日本皮膚科学会宮崎地方会, Mar. 2014.
33.	Tomoya Mizutani, Mika Oshima and Kazutoshi Murao : 新生児皮下脂肪壊死症の1例, 第140回日本皮膚科学会徳島地方会, Dec. 2013.
34.	Yoshihiro Matsudate, Kazutoshi Murao and Yoshiaki Kubo : Rhizomucor variabilisによる皮膚ムーコル症の1例, 第65回日本皮膚科学会西部支部学術大会, Nov. 2013.
35.	Kazutoshi Murao and Yoshiaki Kubo : 有棘細胞癌の分子機構, 第65回日本皮膚科学会西部支部学術大会, Nov. 2013.
36.	Nozomi Fukui, Yoshiaki Kubo, Kazutoshi Murao and 他1名 : アリルイソプロピルアセチル尿素による多発性固定薬疹の1例, 第43回日本皮膚アレルギー・接触皮膚炎学会総会学術大会, Nov. 2013.
37.	Nozomi Fukui, Yoshiaki Kubo, Kazutoshi Murao and 他2名 : Papular acantholytic dyskeratosis of the vulvaの1例, 第65回日本皮膚科学会西部支部学術大会, Nov. 2013.
38.	Yoshihiro Matsudate, Kazutoshi Murao and Yoshiaki Kubo : Folliculotropic mycosis fungoidesの1例, 第29回日本皮膚悪性腫瘍学会学術大会, Aug. 2013.
39.	Yoshihiro Matsudate, Kazutoshi Murao, Yoshiaki Kubo and Jun Kishi : 刺青部の肉芽腫病変を契機に診断に至ったサルコイドーシスの1例, 第112回日本皮膚科学会総会, Jun. 2013.
40.	Mika Oshima, Rie Yamamura, 井上奈津子 and Kazutoshi Murao : エキセナトドによる薬疹の1例, 第139回日本皮膚科学会徳島地方会, Jun. 2013.
41.	Kazutoshi Murao, Mika Oshima and Yoshiaki Kubo : ビタミンD3軟膏外用療法が奏効したverrucous skin lesions on the feet in diabetic neuropathyの1例, 第4回日本臨床皮膚科医会四国ブロック総会・学術大会, May 2013.
42.	Tomoya Mizutani, 井上奈津子, Kazutoshi Murao, Yoshiaki Kubo and Takeshi Ishigami : 脳転移を伴った直腸原発悪性黒色腫の1例, 第81回日本皮膚科学会茨城地方会, Mar. 2013.
43.	Yoshihiro Matsudate, 仙崎聖子 and Kazutoshi Murao : Folliculotropic mycosis fungoidesの1例, 第138回日本皮膚科学会徳島地方会, Dec. 2012.
44.	Yoshihiro Matsudate, 仙崎聖子, Kazutoshi Murao and Yoshiaki Kubo : Ichthyosiform mycosis fungoidesの1例, 第64回日本皮膚科学会西部支部学術大会, Oct. 2012.
45.	Mio Machida, Kenji Hirose, Kazutoshi Murao, Yoshiaki Kubo, 浦野芳夫 and Shin-ichi Ansai : Folliculosebaceous cystic hamartomaの所見を伴った色素性母斑の1例, 第63回日本皮膚科学会西部支部学術大会, Oct. 2011.
46.	Mio Machida, Yasutoshi Hida, Kazutoshi Murao, Yoshiaki Kubo, 岸昌美 and Saburo Sone : 淡黄色小結節を伴ったChurg-Strauss症候群の1例, 第57回日本皮膚科学会高知地方会, Feb. 2011.

Et cetera, Workshop:

1.	Kazutoshi Murao, Yoshiaki Kubo and Kazuhide Mineda : 摘出後に衛星病巣を生じた血管拡張性肉芽腫の1例, 第196回日本皮膚科学会鹿児島地方会, Mar. 2024.
2.	國方江実, 中野里穂, 矢野由夏, Hiromichi Kawashima and Kazutoshi Murao : 頭部の脱毛を生じた粘膜皮膚型尋常性天疱瘡の1例, 第159回日本皮膚科学会徳島地方会, Dec. 2023.
3.	Kazutoshi Murao, 中野里穂, Yoshiaki Kubo and 横田綾 : 下腿に生じた化膿性汗腺炎の1例, 第81回日本皮膚科学会高知地方会, Oct. 2023.
4.	Kanako Yamasaki, 白井宏美, 遠藤理子, 宮本翔子, Mariko Niki, Kazutoshi Murao, Yoshiaki Kubo, 藤本篤夫, 榊哲彦, 田中美緒, 田中龍星 and 丸山治彦 : 多数の虫体を認め治療に難渋しているマンソン孤虫症の1例, 第75回日本皮膚科学会西部支部学術大会, Sep. 2023.
5.	堀優子, Kazutoshi Murao and Yoshiaki Kubo : 一般用創傷被覆剤(キズパワーパッド)による接触蕁麻疹症候群の1例, 第75回日本皮膚科学会西部支部学術大会, Sep. 2023.
6.	Kazutoshi Murao, Kanako Yamasaki and Yoshiaki Kubo : すだちの棘による刺創部に生じたintralymphatic histiocytosisの1例, 第153回日本皮膚科学会広島地方会, Sep. 2023.
7.	遠藤理子, 武市浩美, Kazutoshi Murao and Yoshiaki Kubo : 単発性pseudoatrophic maculeの1例, 第141回日本皮膚科学会山陰地方会, Sep. 2023.
8.	Kazutoshi Murao, Kanako Yamasaki, 堀優子 and Yoshiaki Kubo : 長期間narrow-band UVB治療を行っていた乾癬患者に生じた多発性Bowen病の1例, 第39回日本皮膚悪性腫瘍学会学術大会, Aug. 2023.
9.	宮本翔子, 遠藤理子, 佐藤有莉乃, Hiromichi Kawashima, Kazutoshi Murao, Yoshiaki Kubo and Hirokazu Ogino : 抗PD-L1抗体投与中に発症した表皮の全層壊死を伴う苔癬様皮疹の1例, 第14回日本臨床皮膚科医会四国ブロック, Jul. 2023.
10.	堀優子, Mariko Niki, Hiromichi Kawashima, 木下華子, Kazutoshi Murao, Yoshiaki Kubo, 山本綾香, 石谷祐紀 and 玉置俊輔 : セクキヌマブ投与中可能性胸鎖関節炎を発症した乾癬性関節炎の2例, 第122回日本皮膚科学会総会, Jun. 2023.
11.	宮本翔子, 遠藤理子, 佐藤有莉乃, Hiromichi Kawashima, Kazutoshi Murao, Yoshiaki Kubo and Hirokazu Ogino : 抗PD-L1抗体投与中に生じた表皮の全層性壊死を伴う苔癬様皮疹の1例, 第158回日本皮膚科学会徳島地方会, May 2023.
12.	宮本翔子, 堀優子, 木下華子, Kanako Yamasaki, Kazutoshi Murao and 松田里恵 : 悪性リンパ腫の治療後に生じた多発性エクリン汗孔腫の1例, 第157回日本皮膚科学会徳島地方会, Nov. 2022.
13.	木下華子, Mariko Niki and Kazutoshi Murao : 前頭部に生じたintravenous pyogenic granulomaの1例, 第157回日本皮膚科学会徳島地方会, Nov. 2022.
14.	岩脇文香, 佐藤有莉乃, Kazutoshi Murao and 湯浅真由 : 菌状息肉症患者に生じたdigitate dermatosisの1例, 第157回日本皮膚科学会徳島地方会, Nov. 2022.
15.	遠藤理子, 岩脇文香, Hiromichi Kawashima, Kazutoshi Murao, Yoshiaki Kubo and 長江哲夫 : Benign cephalic histiocytosisの1例, 第157回日本皮膚科学会徳島地方会, Nov. 2022.
16.	木下華子, Kazutoshi Murao and Yoshiaki Kubo : 多形慢性痒疹における血清TARC値の検討:TARC値は丘疹紅皮症との鑑別に有用である, 第74回日本皮膚科学会西部支部学術大会, Oct. 2022.
17.	宮本翔子, Kazutoshi Murao and Yoshiaki Kubo : 右外果に生じた後天性真皮メラノサイト―シスの1例, 第75回日本皮膚科学会愛媛地方会, Oct. 2022.
18.	Kazutoshi Murao, 佐藤有莉乃 and Yoshiaki Kubo : Cutaneous collagenous vasculopathyの1例, 第37回日本皮膚科学会島根地方会, Aug. 2022.
19.	山崎佳那子, 湊優子, 中島美世, Mariko Niki, Kazutoshi Murao, Yoshiaki Kubo, 小川瑛 and Yuya Yamashita : JAK阻害薬投与中に発症した皮膚クリプトコッカス症の1例, 第121回日本皮膚科学会総会, Jun. 2022.
20.	田蒔舞子, 岩脇文香, Kazutoshi Murao, Yoshiaki Kubo, Yasutoshi Hida, 中村秀樹 and 夏賀健 : Kindler症候群の1例, 第121回日本皮膚科学会総会, Jun. 2022.
21.	岩脇文香, 田蒔舞子 and Kazutoshi Murao : 多数の小陥凹病変を呈した皮膚萎縮症の小児例, 第156回日本皮膚科学会徳島地方会, May 2022.
22.	佐藤有莉乃, 六車あずさ, 岩脇文香, Kanako Yamasaki, Kazutoshi Murao, 田蒔舞子, Mariko Niki and Yoshiaki Kubo : 当科で最近経験した頭部血管肉腫の4例, 日本皮膚科学会熊本地方会, Mar. 2022.
23.	Kazutoshi Murao and Yoshiaki Kubo : 顔面に小丘疹を多発し，組織学的に肉芽腫を呈した小児例, 第150回日本皮膚科学会広島地方会, Feb. 2022.
24.	中島美世, Mayu Yuasa, Kazutoshi Murao and Yoshiaki Kubo : 硫酸クロピドグレルによる薬疹の1例, 日本皮膚科学会高知地方会, Jan. 2022.
25.	中島美世, 阿河弘和, Rie Hayashi, Mariko Niki and Kazutoshi Murao : プロテインS欠乏症に合併した下腿潰瘍の1例, 第155回日本皮膚科学会徳島地方会, Dec. 2021.
26.	木下華子, 田蒔舞子, Mio Yada and Kazutoshi Murao : 家族内発症したPanton-Valentine Leukocidin(PVL)陽性市中感染型MRSAによる癤腫症の2例, 第155回日本皮膚科学会徳島地方会, Dec. 2021.
27.	岩脇文香, 山﨑佳那子, 中島美世, Kazutoshi Murao, Yoshiaki Kubo and Masahiro Oura : シアナミドによる薬疹を契機に丘疹-紅皮症を生じたHTLV-1キャリアの1例, 第73回日本皮膚科学会西部支部学術大会, Oct. 2021.
28.	山崎佳那子, 佐藤有莉乃, Mariko Niki, Kazutoshi Murao and Yoshiaki Kubo : 全身に強い色素沈着を伴い，経過中に水疱性類天疱瘡を併発し，CyAが著効した好酸球性環状紅斑(EAE)の1例, 第73回日本皮膚科学会西部支部学術大会, Oct. 2021.
29.	Mariko Niki, Kazutoshi Murao, Yoshiaki Kubo, 吉野真理子 and 石井文人 : 疥癬が先行し抗ラミニンγ1抗体と抗ラミニン332抗体を検出した類天疱瘡の1例, 第73回日本皮膚科学会西部支部学術大会, Oct. 2021.
30.	Kazutoshi Murao and Yoshiaki Kubo : Podoplanin陽性細胞はBowen病のtumor-initiating cellである, 第28回四国四大学講演会, Jul. 2021.
31.	山﨑佳那子, 森あずさ, 木下華子, Rie Hayashi, Kazutoshi Murao, Yoshiaki Kubo and 安齋眞一 : ALK陽性を示したepithelioid fibrous histiocytomaの1例, 第120回日本皮膚科学会総会, Jun. 2021.
32.	Hiromichi Kawashima, 阿河弘和, Rie Hayashi, Mariko Niki, Kazutoshi Murao, Mio Yada and Yoshiaki Kubo : 下腿の創傷を契機に診断した歯周型Ehlers-Danlos症候群の1例, 第120回日本皮膚科学会総会, Jun. 2021.
33.	木下華子, 山崎佳那子, 六車あずさ and Kazutoshi Murao : 好酸球性海綿状態を呈した表在播種型汗孔角化症の1例, 第154回日本皮膚科学会徳島地方会, Jun. 2021.
34.	阿河弘和, 佐藤有莉乃, Rie Hayashi, Mariko Niki and Kazutoshi Murao : 抗BP230陽性水疱性類天疱瘡の1例, 第154回日本皮膚科学会徳島地方会, Jun. 2021.
35.	田蒔舞子, 山﨑佳那子 and Kazutoshi Murao : 皮角を呈した脂腺腺腫の1例, 第154回日本皮膚科学会徳島地方会, Jun. 2021.
36.	佐藤有莉乃, 山﨑佳那子, 木下華子, 祖川麻衣子 and Kazutoshi Murao : Mycobacterium Chelonae感染症の1例, 第153回日本皮膚科学会徳島地方会, Nov. 2020.
37.	山﨑佳那子, Rie Hayashi, Kazutoshi Murao and Yoshiaki Kubo : 下腿蜂窩織炎様の臨床像で再発した節外性 NK/T 細胞リンパ腫の 1 例, 第72回日本皮膚科学会西部支部学術大会, Oct. 2020.
38.	田蒔舞子, Mayu Yuasa, Kazutoshi Murao, Yoshiaki Kubo and 矢野由香 : 踵部に黒色壊死した潰瘍を生じ，好中球性皮膚症と考えた 1 例, 第72回日本皮膚科学会西部支部学術大会, Oct. 2020.
39.	Mariko Niki, 岩脇文香, Kazutoshi Murao and Yoshiaki Kubo : 骨髄移植後の慢性 GVHD 経過中に頭部に多発した有棘細胞癌の 1 例, 第119回日本皮膚科学会総会, Jun. 2020.
40.	山﨑佳那子, 宮本千暁, 祖川麻衣子, Kazutoshi Murao and Yoshiaki Kubo : 出生時より経過を追い 2 歳時に診断に至った Netherton 症候群の 1 例, 第119回日本皮膚科学会総会, Jun. 2020.
41.	横田綾, Kazutoshi Murao, 水口潤 and 川島周 : 透析病院で治療した粉瘤患者についての検討, 第119回日本皮膚科学会総会, Jun. 2020.
42.	雲財崇, 祖川麻衣子 and Kazutoshi Murao : 再燃時に抗体のプロファイルが変わった尋常性天疱瘡の1例, 第152回日本皮膚科学会徳島地方会, Dec. 2019.
43.	山﨑佳那子, 田蒔舞子, Rie Hayashi and Kazutoshi Murao : 下肢の浮腫を伴ったPOEMS症候群の1例, 第152回日本皮膚科学会徳島地方会, Dec. 2019.
44.	岩脇文香, Mariko Niki, 田蒔舞子, Kazutoshi Murao and Yoshiaki Kubo : 頭部に生じたchemical leukodermaの2例, 第152回日本皮膚科学会徳島地方会, Dec. 2019.
45.	Kazutoshi Murao, 小杉知里 and Yoshiaki Kubo : Podoplanin expression in Bowen disease: positive cells can be tumor-initiating cells of Bowen disease, The 44th annual meeting of the Japanese society for investigative dermatology, Nov. 2019.
46.	Mariko Niki, Ayaka Nakasuka, Kazutoshi Murao and Yoshiaki Kubo : Linear cutaneous lupus erythematosus (LCLE)治癒後に，全身性エリテマトーデスを発症した1例, 第71回日本皮膚科学会西部支部学術大会, Sep. 2019.
47.	山﨑佳那子, 祖川麻衣子, Kazutoshi Murao and Yoshiaki Kubo : 骨髄異形成症候群の患者に生じた晩発性皮膚ポルフィリン症の1例, 第71回日本皮膚科学会西部支部学術大会, Sep. 2019.
48.	Tetsuya Hida, Kazutoshi Murao and Yoshiaki Kubo : ウステキヌマブで効果不十分な尋常性乾癬に対するグセルクマブへのバイオスイッチによる有効性の検討, 第34回日本乾癬学会学術大会, Aug. 2019.
49.	宮本千暁, 祖川麻衣子, Kazutoshi Murao and Yoshiaki Kubo : 前胸部に多発する紅色結節を呈したEBV陽性びまん性大細胞型B細胞リンパ腫の1例, 第118回日本皮膚科学会総会, Jun. 2019.
50.	Mayu Yuasa, Kazutoshi Murao, Yoshiaki Kubo and 四方英二 : 外傷性頚部動静脈瘻の1例, 第118回日本皮膚科学会総会, Jun. 2019.
51.	雲財崇, Mio Yada, 宮本千暁, Kazutoshi Murao and Yoshiaki Kubo : 転移性を疑ったが原発巣が見つからなかったmucinous carcinomaの1例, 第35回日本皮膚悪性腫瘍学会学術大会, May 2019.
52.	Kazutoshi Murao, 祖川麻衣子, Mio Yada and Yoshiaki Kubo : 末梢性T細胞リンパ腫患者に生じたinsect bite-like reactionの1例, 第275回日本皮膚科学会岡山地方会, Sep. 2018.
53.	Kazutoshi Murao, Chisato Kosugi and Yoshiaki Kubo : Bowen病におけるpodoplanin発現の検討, 第25回四国四大学皮膚科講演会, Jul. 2018.
54.	Mayu Yuasa, Kazutoshi Murao, Yoshiaki Kubo and Kaoru Keyama : 頭部に生じた原発巣不明のadenocarcinomaの1例, 第34回日本皮膚悪性腫瘍学会学術大会, Jul. 2018.
55.	Masanobu Ootsu, 中島美世, Kazutoshi Murao, Yoshiaki Kubo and Masami Morimoto : Li-Fraumeni症候群に生じた多発性Bowen病の1例, 第117回日本皮膚科学会総会, May 2018.
56.	Mayu Yuasa, Kazutoshi Murao and Yoshiaki Kubo : バラシクロビル内服によって病勢を制御できた再発性多形滲出性紅斑の1例, 第117回日本皮膚科学会総会, May 2018.
57.	Kazutoshi Murao, 木下華子 and Yoshiaki Kubo : 乳頭部に生じた尖圭コンジローマの1例, 第34回日本臨床皮膚科医会総会・臨床学術大会, Apr. 2018.
58.	祖川麻衣子, 山崎佳那子, Masanobu Ootsu and Kazutoshi Murao : Birt-Hogg-Dubé syndromeの1例, 日本皮膚科学会第149回徳島地方会, Dec. 2017.
59.	中島美世, Ayaka Nakasuka, Kazutoshi Murao and Yoshiaki Kubo : シクロスポリン投与中に脂腺増殖症を多発した2例, 第148回日本皮膚科学会徳島地方会, Dec. 2017.
60.	祖川麻衣子, Tetsuya Hida, Kazutoshi Murao, Yoshiaki Kubo and 長江哲夫 : Necrobiotic xanthogranulomaの1例, 日本皮膚科学会第69回西部支部総会, Oct. 2017.
61.	Masanobu Ootsu, Kenji Hirose, 木下華子, Kazutoshi Murao and 井上利之 : 皮膚Rosai-Dorfman病の1例, 第68回日本皮膚科学会西部支部学術大会, Nov. 2016.
62.	Masanobu Ootsu, 木下華子, Kazutoshi Murao, 吉岡正太郎, Junichiro Satomi, Shinji Nagahiro and Yoshiaki Kubo : 頭部IVR施行後に脱毛を生じた1例, 日本皮膚科学会第143回宮崎地方会, Nov. 2015.
63.	Kenji Hirose, 宮本千暁, Kazutoshi Murao, Yoshiaki Kubo, Hirohisa Ogawa and 藤本篤夫 : 顔面に広範囲に多発した偽リンパ腫の1例, 第67回日本皮膚科学会西部支部学術大会, Oct. 2015.
64.	Rie Yamamura, Kenji Hirose, Kazutoshi Murao, Yoshiaki Kubo and 坂尾佳久 : シクロスポリン内服が有効であった小児剣創状強皮症の1例, 第67回日本皮膚科学会西部支部学術大会, Oct. 2015.
65.	幸田舞子, Nozomi Fukui, Kazutoshi Murao and Yoshiaki Kubo : 症状が再燃，遷延し，治療に難渋した薬剤過敏症症候群の1例, 第114回日本皮膚科学会総会，横浜, May 2015.
66.	Mayu Yuasa, Kazutoshi Murao and Yoshiaki Kubo : 糖尿病性腎症・網膜症患者に生じた菌状息肉症の1例, The Japanese Journal of Dermatology, Vol.125, No.4, 945, Apr. 2015. (Keyword) Interferon Gamma(治療的利用)
67.	雲財崇, 新井悠太, 松永直樹, Mayu Yuasa, Kazutoshi Murao and Yoshiaki Kubo : 糖尿病性腎症・網膜症患者に生じた菌状息肉症の1例, Shikoku Acta Medica, Vol.71, No.1-2, 55-56, Apr. 2015. (Keyword) Interferon Gamma(治療的利用)
68.	幸田舞子, Nozomi Fukui, Kenji Hirose and Kazutoshi Murao : ランゲルハンス細胞組織球症の1例, 第142回日本皮膚科学会徳島地方会, Dec. 2014.
69.	Mayu Yuasa, Rie Yamamura, Kazutoshi Murao and Yoshiaki Kubo : 陰茎に生じたcalciphylaxisの1例, 第142回日本皮膚科学会徳島地方会, Dec. 2014.
70.	祖川麻衣子, Yoshihiro Matsudate, Kazutoshi Murao and Yoshiaki Kubo : 尋常性乾癬の患者に掃除た疱疹状天疱瘡の1例, 第21回四国四大学皮膚科研究会, Jun. 2014.
71.	Mika Oshima, Rie Yamamura, 井上奈津子 and Kazutoshi Murao : エキセナチドによる薬疹の1例, 第139回日本皮膚科学会徳島地方会, Jun. 2013.
72.	Tomoya Mizutani, Takeshi Ishigami, Kazutoshi Murao and Yoshiaki Kubo : Multiple cutaneous cavernous malformations associated with cerebral cavernous malformations due to a germline mutation of the PDCD10 gene, The 37th Annural Meeting of the Japanese Society for Investigative Dermatology, Dec. 2012.
73.	Kazutoshi Murao and Yoshiaki Kubo : Human papillomavirus infection in Bowen disease, The 37th annual meeting of the Japanese society of investigative dermatology, Dec. 2012.
74.	大和良輔, Ichiro Hashimoto, Yoshiro Abe, Shinji Matsuo, Katsumasa Ohkawa, Hideki Nakanishi and Kazutoshi Murao : 耳下腺管に生じた扁平上皮癌の1例, 第138回日本皮膚科学会徳島地方会, Dec. 2012.
75.	仁木真理子, Kazutoshi Murao, Yoshiaki Kubo, Ichiro Hashimoto, 柏木圭介, 仙崎雄一 and Hideki Nakanishi : リンパ節転移を伴い，巨大な腫瘍を呈したmucinous carcinoma of the skinの1例, 第138回日本皮膚科学会徳島地方会, Dec. 2012.
76.	Mika Oshima, Kazuhiro Furukita, Kazutoshi Murao and Yoshiaki Kubo : 拒食症患者に見られた壊死性遊走性紅斑様皮疹の1例, 第138回日本皮膚科学会徳島地方会, Dec. 2012.
77.	Natsuko Inoue, Kazutoshi Murao, Yoshiaki Kubo and Hiroyoshi Watanabe : Kaposiform hemangioendothelioma1, 第64回日本皮膚科学会西部支部学術大会, Oct. 2012.
78.	Kazutoshi Murao and Yoshiaki Kubo : 指趾短縮症をともなったwoolly hair nevusの1例, 第63回日本皮膚科学会中部支部学術大会, Oct. 2012.
79.	Tomoya Mizutani, Kazutoshi Murao and Yoshiaki Kubo : 神経性食思不振症の女性に生じた痛風結節, 第362回日本皮膚科学会福岡地方会, Sep. 2012.
80.	緋田哲也, Yoshihiro Matsudate, Kazutoshi Murao, Yoshiaki Kubo and Yasutoshi Hida : 脂漏性角化症病巣内に発症したBowen病の1例, 第28回日本皮膚悪性腫瘍学会学術大会, Jun. 2012.
81.	Mika Oshima, 仙崎聖子, Takeshi Ishigami, Kazutoshi Murao and Yoshiaki Kubo : Radiation-recall phenomenonを伴った性腺刺激ホルモン(LH-RH)アンタゴニスト製剤による薬疹の1例, 第19回四国四大学皮膚科研究会, Jun. 2012.
82.	Rie Yamamura, Kazuhiro Furukita, 緋田哲也, Takeshi Ishigami, Kazutoshi Murao and Yoshiaki Kubo : 広範な脱毛を呈した瘢痕性脱毛症の1例, 第111回日本皮膚科学会総会, Jun. 2012.
83.	Takeshi Ishigami, Kazuhiro Furukita, Kazutoshi Murao and Yoshiaki Kubo : 下大静脈形成不全を認めた難治性下腿潰瘍の1例, 第111回日本皮膚科学会総会, Jun. 2012.
84.	緋田哲也, Mika Oshima, Kazutoshi Murao, Yoshiaki Kubo and Tatsuro Miyamoto : 壊死性強膜炎を伴った壊疽性膿皮症の1例, 第111回日本皮膚科学会総会, Jun. 2012.
85.	Tomoya Mizutani, Mika Oshima, 緋田哲也 and Kazutoshi Murao : Solitary circumscribed neuromaの1例, 第137回日本皮膚科学会徳島地方会, May 2012.
86.	Takeshi Ishigami, Kazuhiro Furukita, Kazutoshi Murao, Yoshiaki Kubo and Yasutoshi Hida : ブシラミンによる薬剤誘発性ループスの2例, 第137回日本皮膚科学会徳島地方会, May 2012.
87.	Kazuhiro Furukita, Rie Yamamura, Kazutoshi Murao and Yoshiaki Kubo : 象皮病の1例, 第51回日本皮膚科学会香川地方会, Mar. 2012.
88.	Takeshi Ishigami, Yasutoshi Hida, Kazutoshi Murao, Yoshihiro Matsudate and Yoshiaki Kubo : The involvement of fibroblast growth factor receptor signaling pathways in dermatofibroma and dermatofibrosarcoma protuberans., The 36th Annual Meeting of the Japanese Society for Investigative Dermatology, Dec. 2011.
89.	Kazutoshi Murao and Yoshiaki Kubo : 尋常性乾癬，円形脱毛症を合併した再発性多発性軟骨炎の1例, 第62回日本皮膚科学会中部支部学術大会, Nov. 2011.
90.	Osamu Miyajima, Kazutoshi Murao, Yoshiaki Kubo and Kyoko Takeuchi : B細胞リンパ腫に合併したbullous smyloidosisの1例, 第63回日本皮膚科学会西部支部学術大会, Oct. 2011.
91.	Mika Oshima, Seiko Senzaki, Takeshi Ishigami, Kazutoshi Murao and Yoshiaki Kubo : Recall phenomenonを呈したLH-RHアゴニスト製剤による薬疹の1例., 第63回日本皮膚科学会西部支部学術大会, Oct. 2011.
92.	Seiko Senzaki, Takeshi Ishigami and Kazutoshi Murao : クリオフィブリノーゲン血症の1例, 第135回日本皮膚科学会徳島地方会, Jun. 2011.
93.	Mika Oshima, Takeshi Ishigami and Kazutoshi Murao : 成人発症型肥満細胞症の1例, 第135回日本皮膚科学会徳島地方会, Jun. 2011.
94.	Takeshi Ishigami, Yasutoshi Hida, Kazutoshi Murao and Yoshiaki Kubo : 間葉系腫瘍における線維芽細胞増殖因子受容体(FGFR)経路の役割, 第18回四国四大学皮膚科研究会, May 2011.
95.	Tomoya Mizutani, Takeshi Ishigami, Kazutoshi Murao and Yoshiaki Kubo : Overlap症候群に合併した皮膚石灰沈着症の1例, 第110回日本皮膚科学会総会, Apr. 2011.
96.	Osamu Miyajima, 鉄谷真由, Takeshi Ishigami, Kazutoshi Murao and Yoshiaki Kubo : 抗ラミニン332型粘膜類天疱瘡を合併した水疱性類天疱瘡の1例, 第110回日本皮膚科学会総会, Apr. 2011.
97.	Mika Oshima, Kazutoshi Murao, Takeshi Ishigami, Yoshiaki Kubo and Seiji Arase : 塩酸ニフェカラントによる皮膚障害の1例., 第134回日本皮膚科学会徳島地方会, Jan. 2011.
98.	Takeshi Ishigami, Yoshiaki Kubo, Kenji Hirose, Yasutoshi Hida and Kazutoshi Murao : 下口唇に皮膚有棘細胞癌を生じた色素性乾皮症バリアント型の1例, 第32回日本光医学・光生物学会, Jul. 2010.
99.	Yasutoshi Hida, 合田慶介, Kazutoshi Murao and Seiji Arase : 泥状花崗斑岩による，中波紫外線照射後の紅斑・色素沈着抑制効果:デジタル画像とイメージJソフトを用いた解析, 第17回四国四大学皮膚科研究会, Jul. 2010.
100.	Kazutoshi Murao, 福本実扶子, Yoshiaki Kubo, Hiroyoshi Watanabe and Seiji Arase : 骨髄移植後に汎発性脱色素斑を生じた1例, 第34回日本小児皮膚科学会学術大会, Jul. 2010.
101.	Yasutoshi Hida, 合田慶介, Kazutoshi Murao, Seiji Arase and 伊藤新次 : 泥状花崗斑岩による，中波紫外線照射後の紅斑・色素沈着抑制効果:デジタル画像とイメージJソフトを用いた解析, 第6回加齢皮膚医学研究会, Jul. 2010.
102.	水谷友哉, 井上奈津子, Daisuke Fukumoto, Kazutoshi Murao and 高橋収 : いちご状血管腫を伴ったHypomelanosis of Itoの2例, 第133回日本皮膚科学会徳島地方会, May 2010.
103.	鉄谷真由, 石上剛史, Kazutoshi Murao, Yoshiaki Kubo and Seiji Arase : 手掌に生じたBowen病の1例, 第109回日本皮膚科学会総会, Apr. 2010.

Grants-in-Aid for Scientific Research (KAKEN Grants Database @ NII.ac.jp)

Identification andcharacterization of skin cancaer stem cells (Project/Area Number: 26461694 )
Identification and characterization of cancer stem cells in skin squamous cell carcinoma. (Project/Area Number: 22591225 )
ヒト乳頭腫ウイルスによる皮膚癌発症機序の解明 (Project/Area Number: 18790790 )
Molecular abnormalities of cell cycle regulations in epidermal keratinocytes for the clinical applications (Project/Area Number: 17591173 )
The research for the classification by molecular biology and the development of a novel therapy in squamous cell carcinomas of the skin (Project/Area Number: 15591180 )
Search by Researcher Number (40363171)

Associate Professor : Murao, Kazutoshi

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Grants-in-Aid for Scientific Research (KAKEN Grants Database @ NII.ac.jp)