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Tokushima University > Graduate School of Technology, Industrial and Social Sciences > Division of Bioscience and Bioindustry > Bioengineering > Biomolecular Functions and Technology >
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Tokushima University > Research Clusters > Research Clusters (Registered) > 1704043 健康長寿社会の実現に向けた徳島県特産物からの機能性分子の創成 >
Tokushima University > Research Clusters > Research Clusters (Selected) > 1903001 次世代型「脳関門創薬」拠点形成:ヒト血液脳関門物流システム解明に基づく脳関門突破型抗体・核酸医薬の開発(立川正憲) >
Tokushima University > Research Clusters > Research Clusters (Registered) > 1703020 実用化を目指した脂質代謝異常症に対する新規予防・治療法開発 >
Tokushima University > Graduate School of Advanced Technology and Science > Life and Materials Systems Engineering > Biological Science and Technology > Biological Reactions >
Tokushima University > Research Clusters > Research Clusters (Registered) > 1804020 ペルオキシソーム蛋白質の遺伝的欠損を背景とする脂質代謝異常症への創薬 >
Tokushima University > Research Clusters > Research Clusters (Registered) > 1904009 有用動物細胞株樹立のための新規ゲノム編集ツール高効率導入法の開発 >
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Research Activity

Field of Study

Lipid Biochemistry, Biochemistry

Subject of Study

Study of bioactive lipid network in health and disease

Book / Paper

Academic Paper (Judged Full Paper):

1. Smriti Binte Sultana Mustafiz, Toru Uyama, Katsuya Morito, Naoko Takahashi, Katsuhisa Kawai, Zahir Hussain, Kazuhito Tsuboi, Nobukazu Araki, Kei Yamamoto, Tamotsu Tanaka and Natsuo Ueda :
Intracellular Ca2+-dependent formation of N-acyl-phosphatidylethanolamines by human cytosolic phospholipase A2ϵ.,
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, Vol.1864, No.12, 158515, 2019.
(DOI: 10.1016/j.bbalip.2019.158515,   Elsevier: Scopus)
2. Akio Mori, Taku Hatano, Tsuyoshi Inoshita, Kahori Shiba-Fukushima, Takahiro Koinuma, Hongrui Meng, Shin-ichiro Kubo, Spencer Spratt, Changxu Cui, Chikara Yamashita, Yoshimi Miki, Kei Yamamoto, Tetsuya Hirabayashi, Makoto Murakami, Yoshikazu Yakahashi, Hideo Shindou, Takashi Nonaka, Masato Hasegawa, Ayami Okuzumi, Yuzuru Imai and Nobutaka Hattori :
Parkinsons disease-associated iPLA2-VIA/PLA2G6 regulates neuronal functions and α-synuclein stability through membrane remodeling,
Proceedings of the National Academy of Sciences of the United States of America, Vol.116, No.41, 20689-20699, 2019.
(DOI: 10.1073/pnas.1902958116,   PubMed: 31548400)
3. S. Sakasegawa, S. Taira, Kei Yamamoto and D. Sugimori :
Enzymatic Synthesis of 1-alkyl-2-hydroxy-sn-glycero-2,3-cyclic-phosphate Using Lysoplasmalogen-specific Phospholipase D.,
European Journal of Lipid Science and Technology : EJLST, 1900227, 2019.
4. Makoto Murakami, Yoshimi Miki, Hiroyasu Sato, Remi Murase, Yoshitaka Taketomi and Kei Yamamoto :
Group IID, IIE, IIF and III secreted phospholipase A2s,
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, Vol.1864, No.6, 803-818, 2019.
(DOI: 10.1016/j.bbalip.2018.08.014,   Elsevier: Scopus)
5. Makoto Murakami, Kei Yamamoto and Yoshitaka Taketomi :
Phospholipase A2 in skin biology: new insights from gene-manipulated mice and lipidomics.,
Inflammation and Regeneration, Vol.38, 31, 2018.
(DOI: 10.1186/s41232-018-0089-2,   PubMed: 30546811)
6. I. Tsukayama, K. Toda, Y. Takeda, T. Mega, M. Tanaka, Y. Kawakami, Y. Takahashi, M. Kimoto, Kei Yamamoto, Y. Miki, M. Murakami and T. Suzuki-Yamamoto :
Preventive effect of Dioscora japonica on squamous cell carcinoma of mouse skin involving down-regulation of prostaglandin E2 synthetic pathway.,
Journal of Clinical Biochemistry and Nutrition, Vol.62, No.2, 139-147, 2018.
(DOI: 10.3164/jcbn.17-54,   PubMed: 29610553)
7. Remi Murase, Yoshitaka Taketomi, Yoshimi Miki, Yasumasa Nishito, Moe Saito, Kiyoko Fukami, Kei Yamamoto and Makoto Murakami :
Group III phospholipase A2 promotes colitis and colorectal cancer.,
Scientific Reports, Vol.7, 12261, 2017.
(Tokushima University Institutional Repository: 112391,   DOI: 10.1038/s41598-017-12434-z,   PubMed: 28947740,   Elsevier: Scopus)
8. Atsushi Irie, Kei Yamamoto, Yoshimi Miki and Makoto Murakami :
Phosphatidylethanolamine dynamics are required for osteoclast fusion.,
Scientific Reports, Vol.7, 46715, 2017.
(Tokushima University Institutional Repository: 112352,   DOI: 10.1038/srep46715,   PubMed: 28436434,   Elsevier: Scopus)
9. Kei Yamamoto, Y. Miki, H. Sato, R. Murase, Y. Taketomi and M. Murakami :
Secreted Phospholipase A2 Specificity on Natural Membrane Phospholipids,
Methods in Enzymology, Vol.583, 101-117, 2017.
(DOI: 10.1016/bs.mie.2016.09.007,   PubMed: 28063487,   Elsevier: Scopus)
10. H. Tanigawa, K. Miyata, Z. Tian, J. Aoi, T. Kadomatsu, S. Fukushima, A. Ogata, N. Takeda, J. Zhao, S. Zhu, K. Terada, M. Endo, J. Morinaga, T. Sugizaki, M. Sato, M. Morioka, I. Manabe, Y. Mashimo, A. Hata, Y. Taketomi, Kei Yamamoto, M. Murakami, K. Araki, M. Jinnin, H. Ihn and Y. Oike :
Upreguration of ANGPTL6 in mouse keratinocytes enhances susceptibility to psoriasis,
Scientific Reports, Vol.6, 34690, 2016.
(Tokushima University Institutional Repository: 112327,   DOI: 10.1038/srep34690,   PubMed: 27698489,   Elsevier: Scopus)
11. Kei Yamamoto, Y. Miki, H. Sato, Y. Nishito, M.H. Gelb, Y. Taketomi and M. Murakami :
Expression and function of group IIE phospholipase A2 in mouse skin.,
The Journal of Biological Chemistry, Vol.291, No.30, 15602-15613, 2016.
(DOI: 10.1074/jbc.M116.734657,   PubMed: 27226633,   Elsevier: Scopus)
12. Y. Miki, Y. Kidoguchi, M. Sato, Y. Taketomi, C. Taya, K. Muramatsu, M.H. Gelb, Kei Yamamoto and M Murakami :
Dual roles of group IID phospholipase A2 in inflammation and cancer.,
The Journal of Biological Chemistry, Vol.291, No.30, 15588-15601, 2016.
(DOI: 10.1074/jbc.M116.734624,   PubMed: 27226632)
13. M. Murakami, Kei Yamamoto, Y. Miki, R. Murase, H. Sato and Y. Taketomi :
The roles of the secreted phospholipase A2 gene family in immunology,
Advances in Immunology, Vol.132, 91-134, 2016.
(DOI: 10.1016/bs.ai.2016.05.001,   PubMed: 27769509,   Elsevier: Scopus)
14. R. Murase, H. Sato, Kei Yamamoto, A. Ushida, Y. Nishito, K. Ikeda, T. Kobayashi, T. Yamamoto, Y. Taketomi and M. Murakami :
Group X secreted phospholipase A2 releases ω-3 polyunsaturated fatty acids, suppresses colitis and promotes sperm fertility,
The Journal of Biological Chemistry, Vol.291, No.13, 6895-6911, 2016.
(DOI: 10.1074/jbc.M116.715672,   PubMed: 26828067,   Elsevier: Scopus)
15. Kei Yamamoto, Yoshimi Miki, Mariko Sato, Yoshitaka Taketomi, Yasumasa Nishito, Choji Taya, Kazuaki Muramatsu, Kazutaka Ikeda, Hiroki Nakanishi, Ryo Taguchi, Naotomo Kambe, Kenji Kabashima, Gérard Lambeau, Michael H. Gelb and Makoto Murakami :
The role of group IIF secreted phospholipase A2 in epidermal homeostasis and hyperplasia.,
The Journal of Experimental Medicine, Vol.212, No.11, 1901-1919, 2015.
(DOI: 10.1084/jem.20141904,   PubMed: 26438362,   Elsevier: Scopus)
16. Rahul Vijay, Xiaoyang Hua, David K. Meyerholz, Yoshimi Miki, Kei Yamamoto, Michael Gelb, Makoto Murakami and Stanley Perlman :
Critical role of phospholipase A2 group IID in age-related susceptibility to severe acute respiratory syndromeCoV infection,
The Journal of Experimental Medicine, Vol.212, No.11, 1851-1868, 2015.
(DOI: 10.1084/jem.20150632,   PubMed: 26392224,   Elsevier: Scopus)
17. Makoto Murakami, Hiroyasu Sato, Yoshimi Miki, Kei Yamamoto and Yoshitaka Taketomi :
A new era of secreted phospholipase A2.,
Journal of Lipid Research, Vol.56, No.7, 1248-1261, 2015.
(DOI: 10.1194/jlr.R058123,   PubMed: 25805806)
18. M. Murakami, Y. Taketomi, Y. Miki, H. Sato, Kei Yamamoto and G. Lambeau :
Emerging roles of secreted phospholipase A2 enzymes: the 3rd edition.,
Biochimie, Vol.107, No.PtA, 105-113, 2014.
(DOI: 10.1016/j.biochi.2014.09.003,   PubMed: 25230085)
19. H. Sato, Y. Taketomi, A. Ushida, Y. Isogai, T. Kojima, T. Hirabayashi, Y. Miki, Kei Yamamoto, Y. Nishito, T. Kobayashi, K. Ikeda, R. Taguchi, S. Hara, S. Ida, Y. Miyamoto, M. Watanabe, H. Baba, K. Miyata, Y. Oike, M.H. Gelb and M. Murakami :
The adipocyte-inducible secreted phospholipases PLA2G5 and PLA2G2E play distinct roles in obesity.,
Cell Metabolism, Vol.20, No.1, 119-132, 2014.
(DOI: 10.1016/j.cmet.2014.05.002,   PubMed: 24910243)
20. Y. Miki, Kei Yamamoto, Y. Taketomi, H. Sato, K. Shimo, T. Kobayashi, Y. Ishikawa, T. Ishii, H. Nakanishi, K. Ikeda, R. Taguchi, K. Kabashima, M. Arita, H. Arai, G. Lambeau, J.M. Bollinger, S. Hara, M.H. Gelb and M. Murakami :
Lymphoid tissue phospholipase A2 group IID resolves contact hypersensitivity by driving anti-inflammatory lipid mediators.,
The Journal of Experimental Medicine, Vol.210, 1217-1234, 2013.
(DOI: 10.1084/jem.20121887,   PubMed: 23690440)
21. Y. Taketomi, N. Ueno, T. Kojima, H. Sato, R. Murase, Kei Yamamoto, S. Tanaka, M. Sakanaka, M. Nakamura, Y. Nishito, M. Kawana, N. Kambe, K. Ikeda, R. Taguchi, S. Nakamizo, K. Kabashima, M.H. Gelb, M. Arita, T. Yokomizo, M. Nakamura, K. Watanabe, H. Hirai, M. Nakamura, Y. Okayama, C. Ra, K. Aritake, Y. Urade, K. Morimoto, Y. Sugimoto, T. Shimizu, S. Narumiya, S. Hara and M. Murakami :
Mast cell maturation is driven via a group III phospholipase A2-prostaglandin D2-DP1 receptor paracrine axis.,
Nature Immunology, Vol.14, No.6, 554-563, 2013.
(DOI: 10.1038/ni.2586,   PubMed: 23624557)
22. H. Ait-Oufella, O. Herbin, C. Lahoute, C. Coatrieux, X. Loyer, J. Joffre, L. Laurans, B. Ramkhelawon, O. Blanc-Brude, S. Karabina, C.A. Girard, C. Payré, Kei Yamamoto, C.J. Binder, M. Murakami, A. Tedgui, G. Lambeau and Z. Mallat :
Group X secreted phospholipase A2 limits the development of atherosclerosis in LDL receptor-null mice: GX sPLA2 reduces atherosclerosis.,
Arteriosclerosis, Thrombosis, and Vascular Biology, Vol.33, 466-473, 2013.
(DOI: 10.1161/ATVBAHA.112.300309)
23. N. Ueno, Y. Taketomi, Kei Yamamoto, T. Hirabayashi, D. Kamei, Y. Kita, T. Shimizu, K. Shinzawa, Y. Tsujimoto, K. Ikeda, R. Taguchi and M. Murakami :
Analysis of two major intracellular phospholipase A2s in mast cells reveals crucial contribution of cPLA2a, not iPLA2b, to lipid mobilization in proximal mast cells and distal fibroblasts.,
The Journal of Biological Chemistry, Vol.286, No.43, 37249-37263, 2011.
(DOI: 10.1074/jbc.M111.290312,   PubMed: 21880721)
24. M. Murakami, Y. Taketomi, H. Sato and Kei Yamamoto :
Phospholipase A2 revisited.,
The Journal of Biochemistry, Vol.150, No.3, 233-255, 2011.
(DOI: 10.1093/jb/mvr088,   PubMed: 21746768)
25. Kei Yamamoto, Y. Isogai, H. Sato, Y. Taketomi and M. Murakami :
Secreted phospholipase A2, lipoprotein hydrolysis, and atherosclerosis: integration with lipidomics.,
Analytical and Bioanalytical Chemistry, Vol.400, No.7, 1829-1842, 2011.
(DOI: 10.1007/s00216-011-4864-z,   PubMed: 21445663)
26. M. Murakami, Y. Taketomi, H. Sato and Kei Yamamoto :
Integrated lipidomics in the secreted phospholipase A2 biology.,
International Journal of Molecular Sciences, Vol.12, No.3, 1474-1495, 2011.
(DOI: 10.3390/ijms12031474,   PubMed: 21673902)
27. H. Sato, Y. Isogai, S. Masuda, Y. Taketomi, Y. Miki, D. Kamei, S. Hara, T. Kobayashi, Y. Ishikawa, T. Ishii, K. Ikeda, R. Taguchi, Y. Ishimoto, N. Suzuki, Y. Yokota, K. Hanasaki, T. Suzuki-Yamamoto, Kei Yamamoto and M. Murakami :
Physiological roles of group X secreted phospholipase A2 in reproduction, gastrointestinal phospholipid digestion, and neuronal function.,
The Journal of Biological Chemistry, Vol.286, No.13, 11632-11648, 2011.
(DOI: 10.1074/jbc.M110.206755,   PubMed: 21266581)
28. Kei Yamamoto, Y. Taketomi, Y. Isogai, Y. Miki, H. Sato, S. Masuda, Y. Nishito, K. Morioka, Y. Ishimoto, N. Suzuki, Y. Yokoya, K. Hanasaki, Y. Ishikawa, T. Ishii, T. Kobayashi, K. Fukami, K. Ikeda, H. Nakanishi, R. Taguchi and M. Murakami :
Hair follicular expression and function of group X secreted phospholipase A2 in mouse skin.,
The Journal of Biological Chemistry, Vol.286, No.13, 11616-11631, 2011.
(DOI: 10.1074/jbc.M110.206714,   PubMed: 21266583)
29. M. Murakami, Y. Taketomi, Y. Miki, H. Sato, T. Hirabayashi and Kei Yamamoto :
Recent progress in phospholipase A2 research: from cells to animals to humans.,
Progress in Lipid Research, Vol.50, No.2, 152-192, 2011.
(DOI: 10.1016/j.plipres.2010.12.001,   PubMed: 21185866,   Elsevier: Scopus)
30. J. Escoffier, I. Jemel, A. Tanemoto, Y. Taketomi, C. Payre, C. Coatrieux, H. Sato, Kei Yamamoto, S. Masuda, K. Pernet-Gallay, V. Pierre, S. Hara, M. Murakami, M.D. Waard, G. Lambeau and C. Arnoult :
Group X phospholipase A2 is released during sperm acrosome reaction and controls fertility outcome in mice.,
The Journal of Clinical Investigation, Vol.120, No.5, 1415-1428, 2010.
(DOI: 10.1172/JCI40494,   PubMed: 20424324)
31. H. Sato, Y. Taketomi, Y. Isogai, Y. Miki, Kei Yamamoto, S. Masuda, T. Hosono, S. Arata, Y. Ishikawa, T. Ishii, T. Kobayashi, H. Nakanishi, K. Ikeda, R. Taguchi, S. Hara, I. Kudo and M. Murakami :
Group III secreted phospholipase A2 regulates epididymal sperm maturation and fertility.,
The Journal of Clinical Investigation, Vol.120, No.5, 1400-1414, 2010.
(DOI: 10.1172/JCI40493,   PubMed: 20424323)
32. M. Murakami, Y. Taketomi, G. Girard, Kei Yamamoto and G. Lambeau :
Emerging roles of secreted phospholipase A2 enzymes: lessons from transgenic and knockout mice.,
Biochimie, Vol.92, No.6, 561-582, 2010.
(DOI: 10.1016/j.biochi.2010.03.015,   PubMed: 20347923)
33. Y. Ishikawa, M. Kimura-Matsumoto, M. Murakami, Kei Yamamoto, Y. Akasaka, M. Uzuki, Y. Yuri, N. Inomata, T. Yokoo and T. Ishii :
Distribution of smooth muscle cells and macrophages expressing scavenger receptor Bi/II in atherosclerosis.,
Journal of Atherosclerosis and Thrombosis, Vol.16, No.6, 829-839, 2009.
(DOI: 10.5551/jat.1941,   PubMed: 20032583)
34. H. Sato, Y. Taketomi, Y. Isogai, S. Masuda, T. Kobayashi, Kei Yamamoto and M. Murakami :
Group III secreted phospholipase A2 transgenic mice spontaneously develop inflammation.,
The Biochemical Journal, Vol.421, No.1, 17-27, 2009.
(DOI: 10.1042/BJ20082429,   PubMed: 19371233)
35. H. Sato, R. Kato, Y. Isogai, G. Saka, M. Ohtsuki, Y. Takketomi, Kei Yamamoto, K. Tsutsumi, J. Yamada, S. Masuda, Y. Ishikawa, T. Ishii, T. Kobayashi, K. Ikeda, R. Taguchi, S. Hatakeyama, S. Hara, I. Kudo, H. Itabe and M. Murakami :
Analyses of group III secreted phospholipase A2 transgenic mice reveals potential participation of this enzyme in plasma lipoprotein modification, macrophage foam cell formation, and atherosclerosis.,
The Journal of Biological Chemistry, Vol.283, No.48, 33483-33497, 2008.
(DOI: 10.1074/jbc.M804628200,   PubMed: 18801741)
36. S. Masuda, Kei Yamamoto, T. Hirabayashi, Y. Ishikawa, T. Ishii, I. Kudo and M. Murakami :
Human group III phospholipase A2 promotes neuronal outgrowth and survival.,
The Biochemical Journal, Vol.409, No.2, 429-438, 2008.
(DOI: 10.1042/BJ20070844,   PubMed: 17868035)
37. M. Ohtsuki, Y. Taketomi, S. Arata, S. Masuda, Y. Ishikawa, T. Ishii, Y. Takanezawa, J. Aoki, H. Arai, Kei Yamamoto, I. Kudo and M. Murakami :
Transgenic expression of group V, but not group X, secreted phospholipase A2 in mice leads to neonatal lethality because of lung dysfunction.,
The Journal of Biological Chemistry, Vol.281, No.47, 36420-36433, 2006.
(DOI: 10.1074/jbc.M607975200,   PubMed: 17008322)
38. Kei Yamamoto, J. Wang, S. Yamamoto and H. Tobe :
Suppression of cyclooxygenase-2 gene transcription by humulon.,
Advances in Experimental Medicine and Biology, Vol.507, No.73, 77, 2002.
39. K. Kurachi, K. Zhang, J. Huo, A. Ameri, M. Kuwahara, J.-M. Fontaine, Kei Yamamoto and S. Kurashi :
Age-related regulation of genes: slow homeostatic changes and age-dimension technology.,
Physica A: Statistical Mechanics and its Applications, Vol.315, 105-113, 2002.
40. M. Shimamura, T. Hazato, H. Ashino, Y. Yamamoto, E. Iwasaki, H. Tobe, Kei Yamamoto and S. Yamamoto :
Inhibition of angiogenesis by humulone, a bitter acid from beer hop.,
Biochemical and Biophysical Research Communications, Vol.289, No.1, 220-224, 2001.
(DOI: 10.1006/bbrc.2001.5934,   PubMed: 11708802,   Elsevier: Scopus)
41. Kei Yamamoto, J. Wang, Y. Sugimoto, A. Ichikawa and S. Yamamoto :
Induction of prostaglandin I2 receptor in murine osteoblastic cell.,
Advances in Prostaglandin and Leukotriene Research, 103-106, 2001.
42. K. Tsboi, Y. Sugimoto, A. Iwane, Kei Yamamoto, S. Yamamoto and A. Ichikawa :
Uterine expression of prostaglandin H2 synthase in late pregnancy and during parturition in prostaglandin F receptor-deficient mice.,
Endocrinology, Vol.141, No.1, 315-324, 2000.
(DOI: 10.1210/en.141.1.315,   PubMed: 10614653,   Elsevier: Scopus)
43. S Yamamoto, N. Ueda, I. Mahmud, H. Yamaguchi, R. Yamashita, Kei Yamamoto, K. Ishimura, Y. Urade, Y. Kanaoka and O. Hayaishi :
Fatty acid cyclooxygenase induction accompanied by prostaglandin D synthesis in a human megakaryoblastic cell line CMK differentiated by phorbol ester.,
BioFactors, Vol.11, 57-61, 2000.
44. H. Sei, D. Saito, Kei Yamamoto, K. Morita and Y. Morita :
Differential effect of short-term REM sleep deprivation on NGF and BDNF protein level in the rat brain.,
Brain Research, Vol.877, 387-390, 2000.
45. Kei Yamamoto, J. Wang, S. Yamamoto and H. Tobe :
Suppression of cyclooxygenase-2 gene transcription by humulon of beer hop extract studied with reference to glucocorticoid.,
FEBS Letters, Vol.877, 387-390, 2000.
46. J. Wang, Kei Yamamoto, Y. Sugimoto, A. Ichikawa and S. Yamamoto :
Induction of prostaglandin I2 receptor by tumor necrosis factor-alpha in osteoblastic MC3T3-E1 cells.,
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, Vol.1441, 69-76, 1999.
(DOI: 10.1016/S1388-1981(99)00139-0,   PubMed: 10526229)
47. S. Yamamoto, N. Ueda, I. Mahmud, H. Yamaguchi, R. Yamashita, Kei Yamamoto, K. Ishimura, Y. Urade, Y. Kanaoka and O. Hayaishi :
Fatty acid cyclooxygenase induction and prostaglandin D synthesis in a human megakaryoblastic cell line CMK differentiated by phorbol ester.,
Advances in Experimental Medicine and Biology, Vol.469, 17-21, 1999.
48. S. Yamamoto, Kei Yamamoto, H. Kurobe, R. Yamashita, H. Yamaguchi and N. Ueda :
Transcriptional regulation of fatty acid cyclooxygenase-1 and 2.,
Int. J. Tiss. Reac., Vol.20, 17-22, 1998.
49. N. Ueda, Y. Kurahashi, Kei Yamamoto and S. Yamamoto :
Anandamide amidohydrolase from porcine brain. Partial purification and characterization.,
Advances in Experimental Medicine and Biology, Vol.407, 323-328, 1997.
50. Kei Yamamoto, T. Arakawa, Y. Taketani, Y. Takahashi, Y. Hayashi, N. Ueda, S. Yamamoto and M. Kumegawa :
TNFa-dependent induction of cyclooxygenase-2 mediated by NFkB and NF-IL6.,
Advances in Experimental Medicine and Biology, Vol.407, 185-189, 1997.
51. Natsuo Ueda, Yuko Kurahashi, Kei Yamamoto, Shozo Yamamoto and Takashi Tokunaga :
Enzymes for anandamide biosynthesis and metabolism.,
Journal of Lipid Mediators and Cell Signalling, Vol.14, No.1-3, 57-61, 1996.
(DOI: 10.1016/0929-7855(96)00509-3,   PubMed: 8906546,   Elsevier: Scopus)
52. H Ikawa, Kei Yamamoto, Y Takahashi, N Ueda, Y Hayashi, S Yamamoto, K Ishimura, M Irahara and T Aono :
Arachidonate 12-lipoxygenase in porcine anterior pituitary cells; its localization and possible function in gonadotrophs.,
The Journal of Endocrinology, Vol.148, 33-41, 1996.
(DOI: 10.1677/joe.0.1480033,   PubMed: 8568469,   Elsevier: Scopus)
53. Y. Harada, K. Hatanaka, M. Kawamura, M. Saito, M. Ogino, M. Majima, T. Ohno, K. Ogino, Kei Yamamoto, Y. Taketani, S. Yamamoto and M. Katori :
Role of prostaglandin H synthase-2 in prostaglandin E2 formation in rat carrageenin-induced pleurisy.,
Prostaglandins, Vol.51, 19-33, 1996.
54. T. Katagi, H. Kataoka, Y. Konishi, Y. Takata, S. Kitano, M. Yamaki, T. Inoi, Kei Yamamoto, S. Yamamoto and Y. Yamagata :
Syntheses and anti-inflammatory activities of O-acyloximes. II.,
Chem. Pharm. Bull., Vol.44, 145-149, 1996.
55. N. Ueda, Kei Yamamoto, Y. Kurahashi, S. Yamamoto, M. Ogawa, N. Matsuki, I. Kudo, H. Shinkai, E. Shirakawa and T. Tokunaga :
Oxygenation of arachidonylethanolamide (anandamide) by lipoxygenases.,
Adv. Prostaglandin Thromboxane Leukot. Res., Vol.23, 163-165, 1995.
56. Kei Yamamoto, T. Arakawa, N. Ueda and S. Yamamoto :
Transcriptional roles of nuclear factor B and nuclear factor- interleukin-6 in the tumor necrosis factor alpha-dependent induction of cyclooxygenase-2 in MC3T3-E1 cells.,
The Journal of Biological Chemistry, Vol.270, 31315-31320, 1995.
57. N. Ueda, Kei Yamamoto, S. Yamamoto, T. Tokunaga, E. Shirakawa, H. Shinkai, M. Ogawa, T. Sato, I. Kudo, K. Inoue, H. Takizawa, T. Nagano, M. Hirobe, N. Matsuki and H. Saito :
Lipoxygenase-catalyzed oxygenation of arachidonylethanolamide, a cannabinoid receptor agonist.,
Biochim. Biophys. Acta, Vol.1254, 127-134, 1995.
58. T. Ohtsuki, M. Matsumoto, Y. Hayashi, Kei Yamamoto, K. Kitagawa, S. Ogawa, S. Yamamoto and T. Kamada :
Reperfusion induces 5-lipoxygenase translocation and leukotriene C4 production in ischemic brain.,
Am. J. Physiol., Vol.268, H1249-H1257, 1995.

Academic Paper (Unrefereed Paper):

1. Kei Yamamoto, Haruka Hakoi, 三木 寿美 and 村上 誠 :
IIF型分泌性ホスホリパーゼA2/リゾプラズマローゲン経路は表皮肥厚性疾患の新規創薬ターゲットである,
Proceedings of the Japanese Conference on the Biochemistry of Lipids, Vol.61, 57-58, 2019.
2. 戸田 圭祐, 津嘉山 泉, 長崎 祐樹, 爲延 麻子, 鴻池 優佳, 我如古 菜月, 伊東 秀之, 川上 祐生, 高橋 吉孝, 三木 寿美, Kei Yamamoto, 村上 誠 and 山本 登志子 :
赤米由来プロアントシアニジンによる5-リポキシゲナーゼ阻害と乾癬予防効果,
Proceedings of the Japanese Conference on the Biochemistry of Lipids, Vol.61, 74-75, 2019.
3. 入江 敦, Kei Yamamoto, 三木 寿美, 武富 芳隆 and 村上 誠 :
破骨細胞における膜リン脂質の代謝動態:PEの合成・輸送・分解と膜融合,
Proceedings of the Japanese Conference on the Biochemistry of Lipids, Vol.59, 79-80, 2017.
4. 山本 登志子, 川井 恵梨佳, 田中 充樹, 長崎 祐樹, 戸田 圭祐, 川上 祐生, 高橋 吉孝, 木本 眞順美, Kei Yamamoto and 村上 誠 :
ウシ生乳中リポカリン型プロスタグランジンD合成酵素の精製と酵素学的性質ならびに乳房炎のバイオマーカーとしての検討,
Proceedings of the Japanese Conference on the Biochemistry of Lipids, Vol.59, 26-28, 2017.
5. 三木 寿美, 城戸 口優, Kei Yamamoto and 村上 誠 :
炎症および癌病態におけるIID型sPLA2の二面的役割,
Proceedings of the Japanese Conference on the Biochemistry of Lipids, Vol.58, 114-116, 2016.
6. Kei Yamamoto, 三木 寿美, 佐藤 弘泰, 武富 芳隆 and 村上 誠 :
皮膚の恒常性と病態における二種のsPLA2の発現と機能,
Proceedings of the Japanese Conference on the Biochemistry of Lipids, Vol.58, 117-118, 2016.
7. 武富 芳隆, 砂川 アンナ, 入江 敦, 三木 寿美, Kei Yamamoto, 佐藤 弘泰, 小林 哲幸 and 村上 誠 :
マスト細胞を制御する第二のAnaphylatic sPLA2の同定,
脂質生化学研究, Vol.58, 119-121, 2016.
8. Kei Yamamoto, 三木 寿美 and 村上 誠 :
IIF型分泌性ホスホリパーゼA2により産生されるアルケニル型リゾホスファチジルエタノールアミンは表皮肥厚性疾患のバイオマーカーである,
Proceedings of the Japanese Conference on the Biochemistry of Lipids, Vol.57, 136-137, 2015.
9. 武富 芳隆, 遠藤 由妃, Kei Yamamoto, 小林 哲幸 and 村上 誠 :
Ⅲ型ホスホリパーゼA2は皮膚バリア恒常性に関わる,
Proceedings of the Japanese Conference on the Biochemistry of Lipids, Vol.57, 138-139, 2015.
10. 入江 敦, Kei Yamamoto and 村上 誠 :
リン脂質動態に基づく破骨細胞融合機構の解明,
Proceedings of the Japanese Conference on the Biochemistry of Lipids, Vol.57, 189-190, 2015.

Review, Commentary:

1. Kei Yamamoto :
リポクオリティを基軸とした新規リゾリン脂質の生理的意義の解明,
The Cell, Vol.50, No.3, 159-160, Mar. 2018.
2. Kei Yamamoto :
リピドミクスが疾患の診断に使われる日も近い?,
Japanese Journal of Clinical Chemistry, Vol.47, No.1, 77-78, Jan. 2018.
3. Kei Yamamoto :
sPLA2のリポクオリティと皮膚疾患,
Journal of Clinical and Experimental Medicine, Vol.264, No.2, 131-136, Jan. 2018.
(CiNii: 40021427246)
4. Kei Yamamoto :
リピドミクスが紐解く新たな脂質代謝,
化学と生物, Vol.55, No.10, 668-675, Sep. 2017.
5. 村上 誠, 三木 寿美 and Kei Yamamoto :
リン脂質代謝酵素によるリポクオリティ制御と炎症・免疫,
Inflammation & Immunology, Vol.25, No.4, 290-297, Jun. 2017.
6. Kei Yamamoto :
The new lipid mediators that modulate skin homeostasis and diseases,
Seikagaku, Vol.88, No.6, 786-790, Dec. 2016.
(DOI: 10.14952/SEIKAGAKU.2016.880786,   PubMed: 29624356,   CiNii: 40021054422,   Elsevier: Scopus)
7. 三木 寿美, Kei Yamamoto and 村上 誠 :
接触性皮膚炎と抗炎症脂質メディエーター,
臨床アレルギー科, Vol.63, 156-163, 2015.
8. 三木 寿美, Kei Yamamoto and 村上 誠 :
疾病における脂質代謝ネットワークの機能.,
オレオサイエンス, Vol.13, No.10, 23-29, 2013.
9. Kei Yamamoto and 村上 誠 :
[Phospholipase A2].,
Seikagaku, Vol.83, No.6, 449-461, Jun. 2011.
(PubMed: 21800676)
10. 佐藤 弘泰, 武富 芳隆, Kei Yamamoto and 村上 誠 :
高脂血症,
生命科学研究の戦略:疾患モデルマウスと表現型解析, 278-287, 2011.
11. 村上 誠, 佐藤 弘泰, 平林 哲也, Kei Yamamoto and 武富 芳隆 :
ホスホリパーゼA2の生理的・病理的役割,
Experimental Medicine, Vol.28, No.20, 114-125, 2010.
12. Kei Yamamoto and 村上 誠 :
ホスホリパーゼA2と炎症,
Inflammation & Immunology, Vol.17, No.4, 359-365, 2009.
13. Kei Yamamoto, 平林 哲也 and 村上 誠 :
ホスホリパーゼA2の多様性と生体内機構,
細胞工学, Vol.26, 1221-1226, 2007.

Proceeding of International Conference:

1. Kei Yamamoto, Haruka Hakoi, Yoshimi Miki and Makoto Murakami :
Group IIF phospholipase A2/lysophosplasmalogen axis is a novel drug target for epidermal-hyperplastic diseases.,
60th International Conference on the Bioscience of Lipids., Tokyo, Jun. 2019.
2. K. Toda, Y. Nagasaki, I. Tsukayama, A. Tanenobu, Y. Konoike, N. Ganeko, H. Ito, Y. Kawakami, Y. Yakanashi, Y. Miki, Kei Yamamoto, M. Murakami and T. Suzuki-Yamamoto :
Inhibition of arachidonate 5-lipoxygenase and improvement in psoriasis by red rice proanthocyanidin.,
60th International Conference on the Bioscience of Lipids, Tokyo, Jun. 2019.
3. L. Liang, K. Heike, T. Kobayashi, T. Hirabayashi, Y. Miki, Kei Yamamoto, Y. Taketomi and M. Murakami :
Group IVE phospholipase A2 (cPLA2e) mobilizes the non-canonical lipid mediator N-acylethanolamine in mouse skin.,
60th International Conference on the Bioscience of Lipids, Tokyo, Jun. 2019.
4. R. Murase, Y. Taketomi, Y. Miki, Kei Yamamoto and M. Murakami :
Distinct roles of phospholipase A2s in colitis and colonic cancer.,
60th International Conference on the Bioscience of Lipids, Tokyo, Jun. 2019.
5. H. Sato, Y. Taketomi, Y. Miki, Kei Yamamoto and M. Murakami :
Group IID phospholipase A2 promotes browning of white adipose tissue and limits obesity.,
60th International Conference on the Bioscience of Lipids, Tokyo, Jun. 2019.
6. Y. Miki, Y. Taketomi, Kei Yamamoto, K. Hosomi, J. Kunisawa, S.G.B Gowda, K. Ikeda, M. Arita and M. Murakami :
Group IIA phospholipase A2 regulates gut microbiome.,
60th International Conference on the Bioscience of Lipids, Tokyo, Jun. 2019.
7. K. Kudou, Y. Miki, H. Higuchi, Kei Yamamoto, M. Murakami and A. Kotani :
Exosome could be the source of lipid mediator in cancer platform.,
60th International Conference on the Bioscience of Lipids, Tokyo, Jun. 2019.
8. Haruka Hakoi and Kei Yamamoto :
The roles of lysoplasmalogen in three-dimensional keratinocyte culture system,
60th International Conference on the Bioscience of Lipids, Tokyo, Jun. 2019.
9. Kei Yamamoto, N Higashizaka, S Fujino, Y Miki and M Murakami :
A plasmalogen-lysophosphatidylethanolamine produced by epidermal sPLA2 (PLA2G2F) is a novel regulator and drug target for epidermal-hyperplasic diseases.,
Bioactive Lipids 2018, Athens, Greece, Mar. 2018.
10. Kei Yamamoto, S. Fujino, Y. Miki and M. Murakami :
An epidermal sPLA2 (PLA2G2F)/plasmalogen-lysophosphatidylethanolamine axis is a novel drug target for epidermal-hyperplastic diseases.,
The 15th International Conference on Bioactive Lipids in Inflammation, Cancer and Related Diseases., Oct. 2017.
11. Y. Miki, Y. Taketomi, Kei Yamamoto and M. Murakami :
Dual roles of group IID phospholipase A2 in inflammation and cancer.,
The 15th International Conference on Bioactive Lipids in Inflammation, Cancer and Related Diseases., Puerto Vallarta, Mexico, Oct. 2017.
12. Kei Yamamoto, S. Fujino, Y. Miki and M. Murakami :
Plasmalogen-lysophosphatidylethanolamine mobilized by an epidermal sPLA2 (PLA2G2F) is a novel regulator and biomarker for epidermal-hyperplasic diseases.,
FASEB Summer Research Conferences on Lysophospholipid and related Mediators., Aug. 2017.
13. Kei Yamamoto, Y. Miki, Y. Taketomi and M. Murakami :
Plasmalogen-lysophosphatidylethanolamine is a novel regulator and biomarker for epidermal-hyperplastic diseases,
The 1st International Plasmalogen Symposium, Nov. 2016.
14. M. Murakami and Kei Yamamoto :
A unique plasmalogen pathway driven by secreted phospholipase A2 regulates skin homeostasis and disease,
The 1st International Plasmalogen Symposium, Nov. 2016.
15. Kei Yamamoto, Y. Miki, H. Sato, Y. Taketomi, G. Lambeau, M.H. Gelb and M. Murakami :
The two secreted phospholipase A2s PLA2G2F and PLA2G2E play distinct roles in skin homeostasis and diseases.,
7th International Conference on Phospholipase A2 and Lipid Mediators, La Jolla, California, USA, May 2016.
16. Kei Yamamoto, Y. Miki, M. Sato, Y. Taketomi, N. Kambe, K. Kabashima, G. Lambeau, M.H. Gelb and M. Murakami :
Plasmalogen-lysophosphatidylethanolamine driven by group IIF sPLA2 underlies epidermal-hyperplastic disorders.,
The 14th International Conference on Bioactive Lipids in Inflammation, Cancer and Related Diseases., Budapest, Hungary, Jul. 2015.
17. Y. Taketomi, Y. Endo, Kei Yamamoto, T. Kobayahsi and M. Murakami :
Skin abnormalities in group III secreted phospholipase A2-deficient mice.,
The 14th International Conference on Bioactive Lipids in Inflammation, Cancer and Related Diseases., Budapest, Hungary, Jul. 2015.
18. R. Murase, Y. Taketomi, H. Sato, Kei Yamamoto, T. Yamamoto and M. Murakami :
Group X sPLA2 mobilizes omega-3 polyunsaturated fatty acid metabolites to protect from colitis.,
The 14th International Conference on Bioactive Lipids in Inflammation, Cancer and Related Diseases., Budapest, Hungary, Jul. 2015.
19. T. Suzuki-Yamamoto, M. Tanaka, E. Kawai, K. Toda, Y. Serai, T. Mega, Y. Kawakami, Y. Takahashi, Kei Yamamoto, M. Murakami and M. Kimoto :
Purification and characterization of bovine lipocalin-type prostaglandin D synthase from cow's milk.,
The 14th International Conference on Bioactive Lipids in Inflammation, Cancer and Related Diseases., Budapest, Hungary, Jul. 2015.
20. I. Tsukayama, Y. Takeda, T. Mega, K. Toda, Y. Kawakami, Y. Takahashi, M. Kimoto, Kei Yamamoto, M. Murakami and T. Suzuki-Yamamoto :
Preventive effect of discorea japonica on squamous cell carcinoma of the mouse skin involving down-regulation of prostaglandin E2 synthetic pathway.,
The 14th International Conference on Bioactive Lipids in Inflammation, Cancer and Related Diseases., Budapest, Hungary, Jul. 2015.
21. I. Tsukayama, Y. Takeda, K. Nakatani, T. Mega, K. Toda, Y. Kawakami, Y. Takahashi, T. Arakawa, Kei Yamamoto, M. Murakami and T. Suzuki-Yamamoto :
Dioscorea japonica suppresses COX-2 and mPGES-1 expression and has preventive effects on squamous cell carcinoma.,
6th International conference on phospholipase A2 and lipid mediators., Tokyo, Feb. 2015.
22. N. Ueno, Y. Taketomi, Kei Yamamoto, T. Hirabayashi, H. Nakanishi and M. Murakami :
Analysis of two major intracellular PLA2 in mast cells reveals crucial contribution of cPLA2a, not iPLA2b, to lipid mobilization in proximal mast cells and distal fibroblasts.,
6th International conference on phospholipase A2 and lipid mediators., Tokyo, Feb. 2015.
23. A. Irie, Kei Yamamoto and M. Murakami :
Phosphatidylethanolamine dynamics in osteoclast fusion.,
6th International conference on phospholipase A2 and lipid mediators., Tokyo, Feb. 2015.
24. R. Murase, Y. Taketomi, H. Sato, Kei Yamamoto, T. Yamamoto and M. Murakami :
Group X sPLA2 protects from colitis by mobilizing omega-3 polyunsaturated fatty acid metabolites.,
6th International conference on phospholipase A2 and lipid mediators., Tokyo, Feb. 2015.
25. H. Sato, Y. Taketomi, Kei Yamamoto, S. Hara, K. Miyata, Y. Oike, M. Gelb and M. Murakami :
Adipocyte-inducible group V and IIE sPLA2s play distinct roles in metabolic disorders.,
6th International conference on phospholipase A2 and lipid mediators., Tokyo, Feb. 2015.
26. H. Sato, Y. Taketomi, Kei Yamamoto, S. Hara and M. Murakami :
Deficiency of group III sPLA2 protects from metabolic disorders.,
6th International conference on phospholipase A2 and lipid mediators., Tokyo, Feb. 2015.
27. Y. Taketomi, N. Ueno, H. Sato, Kei Yamamoto and M. Murakami :
Group III sPLA2 facilitates mast cell maturation.,
6th International conference on phospholipase A2 and lipid mediators., Tokyo, Feb. 2015.
28. Y. Endo, Y. Taketomi, Kei Yamamoto, T. Kobayashi and M. Murakami :
Skin abnormalities in group III sPLA2-deficient mice.,
6th International conference on phospholipase A2 and lipid mediators., Tokyo, Feb. 2015.
29. T. Anjo, T. Hirabayashi, K. Yokoyama, Kei Yamamoto, A. Naoe, J. Ishikawa, A. Muñoz-Garcia, A. Brash and M. Murakami :
Impaired skin barrier function in PNPLA1-deficient mice.,
6th International conference on phospholipase A2 and lipid mediators., Tokyo, Feb. 2015.
30. Yoshimi Miki, Kei Yamamoto and Makoto Murakami :
Group IID sPLA2 resolves psoriasis by driving pro-resolving lipid mediators. 6th International conference on phospholipase A2 and lipid mediators.,
6th International conference on phospholipase A2 and lipid mediators., Tokyo, Feb. 2015.
31. Kei Yamamoto, Yoshimi Miki, Mariko Sato and Makoto Murakami :
Group IIF sPLA2 promotes skin carcinogenesis.,
6th International conference on phospholipase A2 and lipid mediators., Tokyo, Feb. 2015.
32. Kei Yamamoto, Yoshimi Miki, Yoshitaka Taketomi, Naotomo Kambe, Kenji Kabashima, Gerard Lambeau, Michael Gelb and Makoto Murakami :
A unique lipid pathway driven by group IIF sPLA2 undelies epidermal-hyperplasic disorders.,
6th International conference on phospholipase A2 and lipid mediators., Tokyo, Feb. 2015.

Proceeding of Domestic Conference:

1. 長崎 祐樹, 川井 恵梨佳, 田中 充樹, 戸田 圭祐, 津嘉山 泉, 川上 祐生, 高橋 吉孝, 岡崎 愉加, 三木 寿美, Kei Yamamoto, 村上 誠 and 山本 登志子 :
ヒトとウシの乳汁中脂質プロファイル解析,
第92回日本生化学会大会, Sep. 2019.
2. 梁 陸伊韻, 三木 寿美, 平林 哲也, 平家 圭奈子, 小林 哲幸, Kei Yamamoto, 武富 芳隆, 高宮 里奈 and 村上 誠 :
皮膚における新規細胞質型ホスホリパーゼA2(cPLA2e, cPLA2d)の機能解析,
第92回日本生化学会大会, Sep. 2019.
3. 宇山 徹, Binte Mustafiz Smriri Sultana, Katsuya Morito, Naoko Takahashi, 川合 克久, Hussain Zahir, 坪井 一人, 荒木 伸一, Kei Yamamoto, Tamotsu Tanaka and 上田 夏生 :
cPLA2eによるN-アシル‐ホスファチジルエタノールアミンの細胞内カルシウム依存的な生成,
第92回日本生化学会大会, Sep. 2019.
4. Kei Yamamoto :
新規脂質メディエーター,プラズマローゲン型リゾリン脂質の分子機能,
第92回日本生化学会大会 (シンポジウム発表:新しい脂質コミュニケーション)., Sep. 2019.
5. Haruka Hakoi and Kei Yamamoto :
皮膚三次元培養システムを用いたリゾプラズマローゲンの機能の解明,
第92回日本生化学会大会, Sep. 2019.
6. Tsuyoshi Matsugu, Daisuke Tsuji, Ryuto Nakae, Hiromi Teramoto, Daiki Izawa, Kei Yamamoto and Kouji Itou :
ヒトTay-Sachs病神経細胞モデルの構築とGM2ガングリオシドの細胞内局在解析,
第38回日本糖質学会年会, Aug. 2019.
7. Kei Yamamoto :
脂質メタボローム解析が紐解く新しい脂質代謝,
第4回メタボローム解析シンポジウム, Jul. 2019.
8. Kei Yamamoto, Haruka Hakoi, 三木 寿美 and 村上 誠 :
IIF型分泌性ホスホリパーゼA2/リゾプラズマローゲン経路は表皮肥厚性疾患の新規創薬ターゲットである,
第61回日本脂質生化学会, Jul. 2019.
9. 戸田 圭祐, 津嘉山 泉, 長崎 祐樹, 爲延 麻子, 鴻池 優佳, 我如古 菜月, 伊東 秀之, 川上 祐生, 高橋 吉孝, 三木 寿美, Kei Yamamoto, 村上 誠 and 山本 登志子 :
赤米由来プロアントシアニジンによる5-リポキシゲナーゼ阻害と乾癬予防効果,
第61回日本脂質生化学会, Jul. 2019.
10. Kei Yamamoto :
好熱性放線菌ホスホリパーゼDによる表皮肥厚性疾患の緩和,
第9回学際的脂質創生研究部会, Feb. 2019.
11. Ikuta Shirai, Shota Fujino, Rie Mukai, Akihiko Tsuji and Kei Yamamoto :
骨格筋におけるリン脂質代謝系の網羅的脂質メタボローム解析.第41回日本分子生物学会年会,
第41回日本分子生物学会, Nov. 2018.
12. Shota Fujino, Akihiko Tsuji and Kei Yamamoto :
栄養飢餓時に変容するリン脂質代謝の役割,
第41回日本分子生物学会, Nov. 2018.
13. Ryosuke Watanabe, Daisuke Tsuji, Hiroki Tanaka, Shintaroh Michael Uno, Yukiya Ohnishi, Kei Yamamoto, 広川 貴次, 沖野 望, 伊東 信 and Kouji Itou :
Lysoスフィンゴ糖脂質はPI2K/Aktシグナリングの阻害により神経細胞死を引き起こす,
第91回日本生化学会, Sep. 2018.
14. 三木 寿美, 武富 芳隆, Kei Yamamoto, 細見 晃司, 國澤 淳, Gowda Gowda B. Siddabasave, 有田 誠 and 村上 誠 :
IIA型ホスホリパーゼA2は腸内細菌叢を制御する,
第91回日本生化学会, Sep. 2018.
15. Kei Yamamoto :
The combination technology of gene-engineered mice and lipidomics elucidates new lipid pathwaysDiscovery of new bioactive lipid as a regulator of epidermal hyperplastic diseases.,
第33回日本乾癬学会学術大会, Sep. 2018.
16. Ryosuke Watanabe, Daisuke Tsuji, Hiroki Tanaka, Shintaroh Michael Uno, Yukiya Ohnishi, Kei Yamamoto, 広川 貴次, 沖野 望, 伊東 信 and Kouji Itou :
Lysoスフィンゴ糖脂質が神経細胞死を起こす分子メカニズムの解明,
第37回日本糖質学会年会, Aug. 2018.
17. 秦 勝志, Kei Yamamoto, 山本 圭, 西藤 泰昌, 北村 ふじ子, 村上 誠 and 反町 洋之 :
皮膚特異的カルパイン12の活性異常は乾癬の発症に関与する.,
2017年度生命科学系学会合同年次総会(第90回日本生化学会), Dec. 2017.
18. 戸田 圭祐, 長崎 祐樹, 津嘉山 泉, 田中 将夢, 川井 恵梨佳, 我如古 菜月, 伊藤 秀之, 川上 祐生, 高橋 吉孝, 木本 眞順美, 三木 寿美, Kei Yamamoto, 村上 誠 and 山本 登志子 :
赤米プロアントシアニジンによるプロスタグランジンE2産生抑制機構,
2017年度生命科学系学会合同年次総会(第90回日本生化学会), Dec. 2017.
19. 長崎 祐樹, 川井 恵梨佳, 田中 充樹, 戸田 圭祐, 川上 祐生, 高橋 吉孝, 木本 眞順美, 三木 寿美, Kei Yamamoto, 村上 誠 and 山本 登志子 :
ウシ生乳中リポカリン型プロスタグランジンD合成酵素の精製と酵素学的性質ならびに乳房炎のバイオマーカーとしての検討,
2017年度生命科学系学会合同年次総会(第90回日本生化学会), Dec. 2017.
20. Kei Yamamoto, 藤野 翔多, 三木 寿美 and 村上 誠 :
LC-MS/MSを用いた表皮肥厚性疾患を制御する新規生理活性脂質の同定,
第42回 日本医用マススペクトル学会年会, Sep. 2017.
21. 山本 登志子, 川井 恵梨佳, 田中 充樹, 長崎 祐樹, 戸田 圭祐, 川上 祐生, 高橋 吉孝, 木本 眞順美, Kei Yamamoto and 村上 誠 :
ウシ生乳中リポカリン型プロスタグランジンD合成酵素の精製と酵素学的性質ならびに乳房炎のバイオマーカーとしての検討,
日本脂質生化学会, Jun. 2017.
22. 入江 敦, Kei Yamamoto, 三木 寿美, 武富 芳隆 and 村上 誠 :
破骨細胞における膜リン脂質の代謝動態:PEの合成・輸送・分解と膜融合,
日本脂質生化学会, Jun. 2017.
23. Kei Yamamoto :
健康と病態に関わる脂質ネットワークの研究,
第2回BRIGHTシンポジウム, Dec. 2016.
24. 三木 寿美, 城戸口 優, Kei Yamamoto and 村上 誠 :
IID型分泌性ホスホリパーゼA2は皮膚免疫疾患を普遍的に抑制する,
第89回日本生化学会, Sep. 2016.
25. 城戸口 優, Kei Yamamoto, 三木 寿美 and 村上 誠 :
IID型分泌性ホスホリパーゼA2は抗腫瘍免疫を抑制する,
第89回日本生化学会, Sep. 2016.
26. 三木 寿美, 城戸 口優, Kei Yamamoto and 村上 誠 :
炎症および癌病態におけるIID型sPLA2の二面的役割,
第58回 日本脂質生化学会, Jun. 2016.
27. Kei Yamamoto, 三木 寿美, 佐藤 弘泰, 武富 芳隆 and 村上 誠 :
皮膚の恒常性と病態における二種のsPLA2の発現と機能,
第58回 日本脂質生化学会, Jun. 2016.
28. 武富 芳隆, 砂川 アンナ, 入江 敦, 三木 寿美, Kei Yamamoto, 佐藤 弘泰, 小林 哲幸 and 村上 誠 :
マスト細胞を制御する第二のAnaphylatic sPLA2の同定,
第58回 日本脂質生化学会, Jun. 2016.
29. Kei Yamamoto and 村上 誠 :
表皮肥厚性疾患を調節する新しい生理活性脂質の発見,
第57回日本生化学会 中国・四国支部例会, May 2016.
30. 川井 恵理佳, 田中 充樹, 瀬来 由衣, 戸田 圭祐, 目賀 拓斗, 川上 祐生, 高橋 吉孝, 木本 眞順美, Kei Yamamoto, 村上 誠 and 山本 登志子 :
ウシ生乳由来リポカリン型プロスタグランジンD合成酵素の精製と酵素学的性質,
第70回日本栄養・食糧学会大会, May 2016.
31. 津嘉山 泉, 武田 泰典, 戸田 圭祐, 目賀 拓斗, 川上 祐生, 高橋 吉孝, 木本 眞順美, Kei Yamamoto, 村上 誠 and Toshiko Suzuki-Yamamoto :
皮膚癌モデルマウスにおける自然薯の抗炎症・抗腫瘍効果,
日本農芸化学会2016, Mar. 2016.
32. Kei Yamamoto :
表皮肥厚性疾患を調節する新しい脂質メカニズムの発見,
2015年度 第6回学際的脂質創生研究部会, Jan. 2016.
33. 入江 敦, Kei Yamamoto and 村上 誠 :
ホスファチジルエタノールアミンは破骨細胞融合に関与する,
BMB2015, Dec. 2015.
34. 田中 充樹, 木本 眞順美, 川井 恵梨佳, 潮来 由衣, 戸田 圭祐, 目賀 拓斗, 川上 祐生, 高橋 吉孝, Kei Yamamoto, 村上 誠 and 山本-鈴木 登志子 :
牛乳由来リポカリン型プロスタグランジンD合成酵素の精製と酵素学的性質,
BMB2015, Dec. 2015.
35. 城戸口 優, Kei Yamamoto, 三木 寿美 and 村上 誠 :
癌病態におけるIID型分泌性ホスホリパーゼA2の役割,
BMB2015, Dec. 2015.
36. 村瀬 礼美, 武富 芳隆, Kei Yamamoto, 山元 俊憲 and 村上 誠 :
ホスホリパーゼA2分子群を基点とする脂質代謝経路による大腸炎の制御,
第37回生体膜と薬物の相互シンポジウム, Nov. 2015.
37. 入江 敦, Kei Yamamoto and 村上 誠 :
リン脂質動態に基づく破骨細胞融合機構の解明,
第57回日本脂質生化学会, May 2015.
38. Kei Yamamoto, 三木 寿美 and 村上 誠 :
IIF型分泌性ホスホリパーゼA2により産生されるアルケニル型リゾホスファチジルエタノールアミンは表皮肥厚性疾患のバイオマーカーである,
第57回日本脂質生化学会, May 2015.
39. 武富 芳隆, 遠藤 由妃, Kei Yamamoto, 小林 哲幸 and 村上 誠 :
Ⅲ型ホスホリパーゼA2は皮膚バリア恒常性に関わる,
第57回日本脂質生化学会, May 2015.

Et cetera, Workshop:

1. Kei Yamamoto :
The technology of Lipidomics elucidates new lipid pathways: Discovery of new lysophospholipid as a regulator of epidermal hyperplastic diseases.,
National Chiayi University. Chiayi, Taiwan. Seminar., Mar. 2018.
2. Kei Yamamoto :
The technology of Lipidomics elucidates new lipid pathways: Discovery of new lysophospholipid as a regulator of epidermal hyperplastic diseases.,
Wayne state University. Detroit, MI, USA. Seminar, Oct. 2017.

Patent:

1. Kei Yamamoto, 村上 誠 and 酒瀬川 信一 : 表皮肥厚性疾患及び/又は表皮肥厚性症状に対する予防,改善,又は治療剤, 2017-100149 (May 2017), PCT/JP2018/19345 (May 2018).
2. 村上 誠 and Kei Yamamoto : PLA2G2Fを指標とした表皮角化細胞の過増殖性疾患に対する薬剤のスクリーニング方法, 2013-240871 (Nov. 2013), 2014-121318 (Jul. 2014), 6505361 (Apr. 2019).
3. 村上 誠 and Kei Yamamoto : PLA2G2Fを指標とした抗皮膚癌薬のスクリーニング方法, 2012-255316 (Nov. 2012), .

Grants-in-Aid for Scientific Research (KAKEN Grants Database @ NII.ac.jp)

  • 新規脂質メディエーター、プラズマローゲン型リゾリン脂質の分子機構の解明 (Project/Area Number: 19H03372 )
  • リポクオリティを基軸とした新規リゾリン脂質の生理的意義の解明 (Project/Area Number: 16H01372 )
  • New paradigm of lipid metabolism in health sciences (Project/Area Number: 16H02613 )
  • Assessment of high functionality of Dioscorea japonica and development of dysphagia diet using the yam (Project/Area Number: 15K00792 )
  • Identification of new skin disease biomarkers by lipid metabolome analyses and establishment of foundation for medical treatment (Project/Area Number: 26461671 )
  • Exploration of food functionality of Dioscorea japonica targeting lipid mediator (Project/Area Number: 24500948 )
  • Analyses of lipid network using inflammatory dermatoses model mice (Project/Area Number: 23591665 )
  • Elucidation of possible functional mechanisms of secretory phospholipase A2 in skin pathophysiology (Project/Area Number: 21791106 )
  • Physiological functions of secreted phospholipase A_2 enzymes (Project/Area Number: 21390027 )
  • Analyses of pathophysiological functions of prostaglandin E synthases as a potential target for novel anti-inflammatory drugs (Project/Area Number: 18390033 )
  • シクロオキシゲナーゼ-2の誘導とグルココルチコイドによる抑制機構に関する研究 (Project/Area Number: 11770074 )
  • Study on Cyclooxygenase Isozymes for Development of Anti-inflammatory Drugs (Project/Area Number: 10557021 )
  • Search by Researcher Number (30304504)