徳島大学 / 教育研究者総覧 --- 髙栁俊夫

個人のホームページ

https://www.chem.tokushima-u.ac.jp/B1/index.html

https://researchmap.jp/read0185714 (researchmap)

https://orcid.org/0000-0002-5767-1126 (ORCID)

専門分野

○	分析化学 (Analytical Chemistry)

研究テーマ

○	システム論的手法に基づく分離法，分析法の開発 (キャピラリー電気泳動, フローインジェクション分析, グリーン分析化学)

著書・論文

著書:

1.	Toshio Takayanagi and Shoji Motomizu : Chap. 7 Equilibrium Analysis of Weak Chemical Reactions in an Aqueous Solution via the Capillary Electrophoretic Method, Nova Science Publishers © Copyright 2004 - 2018, New York, Feb. 2018.
2.	今任稔彦, 角田欣一, 髙栁俊夫 : クリスチャン分析化学原著7版 II機器分析編 Chapter 21 液体クロマトグラフィーと電気泳動法, 丸善株式会社, 2017年1月.
3.	今任稔彦, 角田欣一, 髙栁俊夫 : クリスチャン分析化学原著7版 II機器分析編 Chapter 18 試料調製:溶媒抽出と固相抽出, 丸善株式会社, 2017年1月.
4.	澤田清編, 髙栁俊夫 : 若手研究者のための機器分析ラボガイド, 講談社サイエンティフィック, 東京, 2006年3月.
5.	梅澤喜夫他編, 髙栁俊夫 : 基礎分析化学実験, 株式会社東京化学同人, 東京, 2004年4月.
6.	岩澤康裕編, 髙栁俊夫 : 化学便覧基礎編改訂5版, 丸善株式会社, 東京, 2004年2月.
7.	梅澤喜夫他編, 髙栁俊夫 : 分析化学実験, 株式会社東京化学同人, 東京, 1999年4月.
8.	四ツ柳隆夫他編, 髙栁俊夫 : 分析化学反応の基礎演習と実験, 培風館, 東京, 1994年10月.

学術論文(審査論文):

1.	Yukuto Ogawa, Sohei Tsugita, Yuka Torii, Hiten Iwamoto, Tsukasa Sato, Jiro Kasahara, Masaki Takeuchi, Tomohiko Kuwabara, Masamitsu Iiyama, Toshio Takayanagi and Hitoshi Mizuguchi : Microdialysis-integrated HPLC system with dual-electrode detection using track-etched membrane electrodes for in vivo monitoring of dopamine dynamics, Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences, Vol.1247, 124318, 2024. (要約) A capillary high-performance liquid chromatography (HPLC) system equipped with a dual-electrode detector utilizing track-etched membrane electrodes (TEMEs) was combined with a microdialysis sampling setup. The electrochemical detector benefits from the high electrolysis efficiency of TEMEs, allowing for calibration-free coulometric detection and simplifying data analysis to determine the dopamine recovery through a dialysis probe. Additionally, this system was used for in vivo monitoring of dopamine in the right striatum of a mouse brain. Temporal changes in dopamine levels, including an exponential decay immediately after the dialysis probe insertion and an excess release of dopamine induced by a high concentration of potassium ions, confirmed the system's proper operation. Furthermore, subsequent measurements following the intraperitoneal injection of mirtazapine showed no increase in dopamine levels in the right dorsal striatum. The dual-electrode system displayed characteristic dopamine detection behavior, with anodic and cathodic peak pairs indicative of reversible electrochemical reactions. This capability facilitated the identification of the dopamine peak within the complex chromatogram of the mouse brain dialysate. The consistency between dopamine collection efficiency from standard solutions and dialysate indicated the absence of interfering electroactive substances overlapping with the dopamine peak in the chromatogram. This integrated analysis system successfully tracked temporal fluctuations in dopamine concentration within the mouse brain. (徳島大学機関リポジトリ) ● Metadata: 119613 (出版サイトへのリンク) ● Publication site (DOI): 10.1016/j.jchromb.2024.124318 (文献検索サイトへのリンク) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 39299150 ● Summary page in Scopus @ Elsevier: 2-s2.0-85204058127 (徳島大学機関リポジトリ: 119613, DOI: 10.1016/j.jchromb.2024.124318, PubMed: 39299150, Elsevier: Scopus)
2.	垣谷柚衣, 飯山真充, 髙栁俊夫, 水口仁志 : 活性炭チャンバを挟持したフィルター電極システムを用いる流通式電位差計測型残留塩素センサ, 分析化学, Vol.73, No.9, 545-551, 2024年. (キーワード) Flow-through potentiometric sensor / track-etched membrane electrode / 活性炭 (activated carbon) / residual chlorine (出版サイトへのリンク) ● Publication site (DOI): 10.2116/bunsekikagaku.73.545 (文献検索サイトへのリンク) ● Search Scopus @ Elsevier (DOI): 10.2116/bunsekikagaku.73.545 (DOI: 10.2116/bunsekikagaku.73.545)
3.	Toshio Takayanagi, Taiki Hirose, Hitoshi Mizuguchi, Hirotaka Okabe and Naoki Matsuda : Capillary Electrophoretic Characterization of Platinum and Silver Nanoparticles in Aqueous Solution Prepared by a Solution Plasma Process, Chromatography, Vol.45, No.1, 23-29, 2024. (キーワード) Platinum nanoparticles / Silver nanoparticles / Capillary zone electrophoresis / Solution plasma process (徳島大学機関リポジトリ) ● Metadata: 119065 (出版サイトへのリンク) ● Publication site (DOI): 10.15583/jpchrom.2023.022 (文献検索サイトへのリンク) ● CiNii @ 国立情報学研究所 (CRID): 1390862312548484608 ● Search Scopus @ Elsevier (DOI): 10.15583/jpchrom.2023.022 (徳島大学機関リポジトリ: 119065, DOI: 10.15583/jpchrom.2023.022, CiNii: 1390862312548484608)
4.	Toshio Takayanagi, Koji Miyake, Seto Minamo, Hitoshi Mizuguchi, Okabe Hirotaka and Matsuda Naoki : Conjugation monitoring of gold nanoparticles with alkanedithiols by capillary zone electrophoresis, Analytical Sciences, Vol.39, No.7, 1033-1039, 2023. (徳島大学機関リポジトリ) ● Metadata: 117986 (出版サイトへのリンク) ● Publication site (DOI): 10.1007/s44211-023-00299-4 (文献検索サイトへのリンク) ● Search Scopus @ Elsevier (DOI): 10.1007/s44211-023-00299-4 (徳島大学機関リポジトリ: 117986, DOI: 10.1007/s44211-023-00299-4)
5.	Toshio Takayanagi, Hiroya Shimizu, Masanori Mine and Hitoshi Mizuguchi : Kinetic Analyses of Two-steps Enzymatic Oxidation from Hypoxanthine to Uric Acid with Xanthine Oxidase by Capillary Electrophoresis/Dynamic Frontal Analysis, Chromatography, Vol.44, No.2, 61-67, 2023. (徳島大学機関リポジトリ) ● Metadata: 118376 (出版サイトへのリンク) ● Publication site (DOI): 10.15583/jpchrom.2023.009 (文献検索サイトへのリンク) ● Search Scopus @ Elsevier (DOI): 10.15583/jpchrom.2023.009 (徳島大学機関リポジトリ: 118376, DOI: 10.15583/jpchrom.2023.009)
6.	Hitoshi Mizuguchi, Hiroto Takeda, Kyosuke Kinoshita, Masaki Takeuchi, Toshio Takayanagi, Norio Teramae, William Pipkin, Kazuko Matsui, Atsushi Watanabe and Chuichi Watanabe : Direct analysis of airborne microplastics collected on quartz filters by pyrolysis-gas chromatography/mass spectrometry, Journal of Analytical and Applied Pyrolysis, Vol.171, 105946, 2023. (徳島大学機関リポジトリ) ● Metadata: 118027 (出版サイトへのリンク) ● Publication site (DOI): 10.1016/j.jaap.2023.105946 (文献検索サイトへのリンク) ● Summary page in Scopus @ Elsevier: 2-s2.0-85149373047 (徳島大学機関リポジトリ: 118027, DOI: 10.1016/j.jaap.2023.105946, Elsevier: Scopus)
7.	Hitoshi Mizuguchi, Soma Fujiki, Takaki Shibata, Masatsugu Oishi, Masamitsu Iiyama, Toshio Takayanagi, Yu-Chi Lin and Min-Hsin Yeh : A flow-based enzyme-free biosensor fabricated using track-etched membrane electrodes: Selective and sensitive detection of uric acid, Sensors and Actuators B: Chemical, Vol.383, 133588, 2023. (キーワード) Track-etched membrane electrode / enzyme-free electrochemical biosensor / uric acid / acetylene black / 2-aminoethanethiol (徳島大学機関リポジトリ) ● Metadata: 117991 (出版サイトへのリンク) ● Publication site (DOI): 10.1016/j.snb.2023.133588 (文献検索サイトへのリンク) ● CiNii @ 国立情報学研究所 (CRID): 1360580230630582784 ● Summary page in Scopus @ Elsevier: 2-s2.0-85149409405 (徳島大学機関リポジトリ: 117991, DOI: 10.1016/j.snb.2023.133588, CiNii: 1360580230630582784, Elsevier: Scopus)
8.	北條三奈, 河野俊貴, 棚田智大, 飯山真充, 髙栁俊夫, 水口仁志 : 紫外線照射下での光分解反応速度の違いに基づく遊離塩素と結合塩素のFIA同時定量, 分析化学, Vol.72, No.1.2, 25-32, 2023年. (出版サイトへのリンク) ● Publication site (DOI): 10.2116/bunsekikagaku.72.25 (文献検索サイトへのリンク) ● Summary page in Scopus @ Elsevier: 2-s2.0-85147666705 (DOI: 10.2116/bunsekikagaku.72.25, Elsevier: Scopus)
9.	Tomohiko Kuwabara, Rikuo Hashimoto, Kenji Matsumoto, Hiroki Hotta, Masamitsu Iiyama, Toshio Takayanagi and Hitoshi Mizuguchi : Detection behavior of phenolic compounds in a dual-electrode system assembled from track-etched membrane electrodes, Journal of Electroanalytical Chemistry, Vol.928, 117039, 2023. (徳島大学機関リポジトリ) ● Metadata: 117823 (出版サイトへのリンク) ● Publication site (DOI): 10.1016/j.jelechem.2022.117039 (文献検索サイトへのリンク) ● CiNii @ 国立情報学研究所 (CRID): 1360580230614607616 ● Summary page in Scopus @ Elsevier: 2-s2.0-85145657289 (徳島大学機関リポジトリ: 117823, DOI: 10.1016/j.jelechem.2022.117039, CiNii: 1360580230614607616, Elsevier: Scopus)
10.	Masanori Mine, Hitoshi Mizuguchi and Toshio Takayanagi : Kinetic analyses of two-steps oxidation from L-tyrosine to L-dopaquinone with tyrosinase by capillary electrophoresis/dynamic frontal analysis, Analytical Biochemistry: Methods in the Biological Sciences, Vol.655, 114856, 2022. (要約) Tyrosinase catalyzes the oxidation of l-tyrosine in two stages to produce l-dopa and l-dopaquinone stepwise, and l-dopaquinone is subsequently converted to dopachrome. Most of the conventional analyses subjected only one-step reaction from l-tyrosine to l-dopa or from l-dopa to l-dopaquinone. In this study, kinetic analyses of two-steps oxidation of l-tyrosine with tyrosinase were made by capillary electrophoresis/dynamic frontal analysis (CE/DFA). When l-dopa was introduced into a capillary as a sample plug in a CE/DFA format, the enzymatic oxidation continuously occurred during the electrophoresis, and the product l-dopaquinone was subsequently converted to dopachrome which was detected as a plateau signal. A Michaelis-Menten constant of the second-step kinetic reaction, K, was determined as 0.45 ± 0.03 mmol L. In the analysis of the first-step kinetic reaction from l-tyrosine to l-dopa, l-dopa was not resolved by CE/DFA because both l-tyrosine and l-dopa are electrically neutral. The l-dopa formed and co-migrated at the l-tyrosine zone was calibrated beforehand with the final product of dopachrome detected as a plateau signal. Constantly formed l-dopa was successfully detected as a plateau signal of dopachrome, and a Michaelis-Menten constant of K was also determined as 0.061 ± 0.009 mmol L by the CE/DFA. CE/DFA is applicable to two-steps enzymatic reactions. (キーワード) Benzoquinones / Dihydroxyphenylalanine / Electrophoresis, Capillary / Kinetics / Monophenol Monooxygenase / Tyrosine (徳島大学機関リポジトリ) ● Metadata: 117346 (出版サイトへのリンク) ● Publication site (DOI): 10.1016/j.ab.2022.114856 (文献検索サイトへのリンク) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 35964734 ● Search Scopus @ Elsevier (PMID): 35964734 ● Search Scopus @ Elsevier (DOI): 10.1016/j.ab.2022.114856 (徳島大学機関リポジトリ: 117346, DOI: 10.1016/j.ab.2022.114856, PubMed: 35964734)
11.	Toshio Takayanagi, Koji Miyake, Sohta Iwasaki, Daiki Uehara, Hitoshi Mizuguchi, Hirotaka Okabe and Naoki Matsuda : Highly stable gold nanoparticles in an aqueous solution without any stabilizer prepared by a solution plasma process evaluated through capillary zone electrophoresis, Analytical Sciences, Vol.38, No.9, 1199-1206, 2022. (徳島大学機関リポジトリ) ● Metadata: 117399 (出版サイトへのリンク) ● Publication site (DOI): 10.1007/s44211-022-00149-9 (文献検索サイトへのリンク) ● Search Scopus @ Elsevier (DOI): 10.1007/s44211-022-00149-9 (徳島大学機関リポジトリ: 117399, DOI: 10.1007/s44211-022-00149-9)
12.	Hitoshi Mizuguchi, Taniguchi Yusuke, Suherman SUHERMAN, Kinichi MORITA, Toshio Takayanagi and Yasutada SUZUKI : An Improved Reflection Colorimeter Integrated with a Coaxial Optical-fiber Cable for Highly Sensitive Solid-phase Colorimetry Using a Membrane Filter, Analytical Sciences, Vol.37, No.7, 1045-1048, 2021. (徳島大学機関リポジトリ) ● Metadata: 115544 (出版サイトへのリンク) ● Publication site (DOI): 10.2116/analsci.20N033 (文献検索サイトへのリンク) ● Summary page in Scopus @ Elsevier: 2-s2.0-85112124251 (徳島大学機関リポジトリ: 115544, DOI: 10.2116/analsci.20N033, Elsevier: Scopus)
13.	Tanikami Yuki, Hitoshi Mizuguchi and Toshio Takayanagi : Determination of Two-Steps Acid Dissociation Constants of L-Ascorbic Acid by Capillary Zone Electrophoresis, Chromatography, Vol.42, No.1, 49-54, 2021. (徳島大学機関リポジトリ) ● Metadata: 115578 (出版サイトへのリンク) ● Publication site (DOI): 10.15583/jpchrom.2020.024 (文献検索サイトへのリンク) ● Search Scopus @ Elsevier (DOI): 10.15583/jpchrom.2020.024 (徳島大学機関リポジトリ: 115578, DOI: 10.15583/jpchrom.2020.024)
14.	Mine Masanori, Hitoshi Mizuguchi and Toshio Takayanagi : Kinetic analysis of the transphosphorylation with creatine kinase by pressure-assisted capillary electrophoresis/dynamic frontal analysis, Analytical and Bioanalytical Chemistry, Vol.413, No.5, 1453-1460, 2021. (徳島大学機関リポジトリ) ● Metadata: 115494 (出版サイトへのリンク) ● Publication site (DOI): 10.1007/s00216-020-03110-9 (文献検索サイトへのリンク) ● Search Scopus @ Elsevier (DOI): 10.1007/s00216-020-03110-9 (徳島大学機関リポジトリ: 115494, DOI: 10.1007/s00216-020-03110-9)
15.	Mine Masanori, Matsumoto Naoya, Hitoshi Mizuguchi and Toshio Takayanagi : Kinetic analysis of an enzymatic hydrolysis of p-nitrophenyl acetate with carboxylesterase by pressure-assisted capillary electrophoresis/dynamic frontal analysis, Analytical Methods, Vol.12, No.48, 5846-4851, 2020. (徳島大学機関リポジトリ) ● Metadata: 115487 (出版サイトへのリンク) ● Publication site (DOI): 10.1039/D0AY01736A (文献検索サイトへのリンク) ● Search Scopus @ Elsevier (DOI): 10.1039/D0AY01736A (徳島大学機関リポジトリ: 115487, DOI: 10.1039/D0AY01736A)
16.	Masanori Mine, Hitoshi Mizuguchi and Toshio Takayanagi : Kinetic analysis of substrate competition in enzymatic reactions with β-D-galactosidase by capillary electrophoresis / dynamic frontal analysis, Journal of Pharmaceutical and Biomedical Analysis, Vol.188, 113390, 2020. (徳島大学機関リポジトリ) ● Metadata: 114775 (出版サイトへのリンク) ● Publication site (DOI): 10.1016/j.jpba.2020.113390 (文献検索サイトへのリンク) ● Search Scopus @ Elsevier (DOI): 10.1016/j.jpba.2020.113390 (徳島大学機関リポジトリ: 114775, DOI: 10.1016/j.jpba.2020.113390)
17.	Toshio Takayanagi, Sota Iwasaki, Yuta Becchaku, S. Yabe, K. Morita, Hitoshi Mizuguchi and N. Hirayama : Capillary Electrophoretic Characterization of Water-Soluble Carbon Nanodots Formed from Glutamic Acid and Boric Acid under Microwave Irradiation, Analytical Sciences, Vol.36, No.8, 941-946, 2020. (徳島大学機関リポジトリ) ● Metadata: 114230 (出版サイトへのリンク) ● Publication site (DOI): 10.2116/analsci.19P484 (文献検索サイトへのリンク) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 32009023 ● Search Scopus @ Elsevier (PMID): 32009023 ● Search Scopus @ Elsevier (DOI): 10.2116/analsci.19P484 (徳島大学機関リポジトリ: 114230, DOI: 10.2116/analsci.19P484, PubMed: 32009023)
18.	Yuki Tanikami, Takuma Tagami, Mayu Sakamoto, Yukihiro Arakawa, Hitoshi Mizuguchi, Yasushi Imada and Toshio Takayanagi : Determination of acid dissociation constants of flavin analogues by capillary zone electrophoresis, Electrophoresis, Vol.41, No.15, 1316-1325, 2020. (要約) Acid dissociation constants (pK ) of nine kinds of flavin analogues as molecular catalyst candidates were determined by CZE. Although some of the analogues are instable and degradable under the light exposure or in alkaline aqueous solutions, the effective electrophoretic mobility of the flavin analogue of interest has been measured with the residual substance. The pK values of the flavin analogues were analyzed through the changes in the effective electrophoretic mobility with varying pH of the separation buffer. One or two steps pK values were determined by the analysis. One of the degraded species from the flavin analogues, lumichrome, was also detected in the CZE analysis, and its pK values were also determined. While coexisting impurities generated over the storage conditions were found in some analogues, the pK values of the target analogues were successfully determined with the help of the CZE separations. A pressure-assisted CZE was utilized for the determination or the estimation of the pK values of such analogues as possessing carboxylic acid moiety. (徳島大学機関リポジトリ) ● Metadata: 114776 (出版サイトへのリンク) ● Publication site (DOI): 10.1002/elps.202000066 (文献検索サイトへのリンク) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 32386342 ● Search Scopus @ Elsevier (PMID): 32386342 ● Search Scopus @ Elsevier (DOI): 10.1002/elps.202000066 (徳島大学機関リポジトリ: 114776, DOI: 10.1002/elps.202000066, PubMed: 32386342)
19.	Toshio Takayanagi, Mine Masanori and Hitoshi Mizuguchi : Capillary Electrophoresis/Dynamic Frontal Analysis for the Enzyme Assay of 4-Nitrophenyl Phosphate with Alkaline Phosphatase, Analytical Sciences, Vol.36, No.7, 829-834, 2020. (徳島大学機関リポジトリ) ● Metadata: 114229 (出版サイトへのリンク) ● Publication site (DOI): 10.2116/analsci.19P471 (文献検索サイトへのリンク) ● Search Scopus @ Elsevier (DOI): 10.2116/analsci.19P471 (徳島大学機関リポジトリ: 114229, DOI: 10.2116/analsci.19P471)
20.	Toshio Takayanagi, Sota Iwasaki, MORITA Kotaro, HIRAYAMA Naoki and Hitoshi Mizuguchi : Capillary Electrophoretic Characterization of Carbon Nanodots Prepared from Glutamic Acid in an Electric Furnace, Chromatography, Vol.41, No.2, 103-107, 2020. (徳島大学機関リポジトリ) ● Metadata: 114846 (出版サイトへのリンク) ● Publication site (DOI): 10.15583/jpchrom.2020.010 (文献検索サイトへのリンク) ● Search Scopus @ Elsevier (DOI): 10.15583/jpchrom.2020.010 (徳島大学機関リポジトリ: 114846, DOI: 10.15583/jpchrom.2020.010)
21.	Hitoshi Mizuguchi, Nishimori Daichi, Tomohiko Kuwabara, Masaki Takeuchi, Iiyama Masamitsu and Toshio Takayanagi : Track-etched membrane-based dual-electrode coulometric detector for microbore/capillary high-performance liquid chromatography, Analytica Chimica Acta, Vol.1102, 46-52, 2020. (徳島大学機関リポジトリ) ● Metadata: 114099 (出版サイトへのリンク) ● Publication site (DOI): 10.1016/j.aca.2019.12.045 (文献検索サイトへのリンク) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 32043995 ● Summary page in Scopus @ Elsevier: 2-s2.0-85076850164 (徳島大学機関リポジトリ: 114099, DOI: 10.1016/j.aca.2019.12.045, PubMed: 32043995, Elsevier: Scopus)
22.	伊藤大地, 水口仁志, 髙栁俊夫 : キャピラリーゾーン電気泳動法によるカテコールアミン類の酸解離定数の決定, 分析化学, Vol.68, No.11, 871-876, 2019年. (徳島大学機関リポジトリ) ● Metadata: 114228 (出版サイトへのリンク) ● Publication site (DOI): 10.2116/bunsekikagaku.68.871 (文献検索サイトへのリンク) ● Search Scopus @ Elsevier (DOI): 10.2116/bunsekikagaku.68.871 (徳島大学機関リポジトリ: 114228, DOI: 10.2116/bunsekikagaku.68.871)
23.	Toshio Takayanagi, Mizuta Yuto, Yuta Becchaku and Hitoshi Mizuguchi : Dispersion of Graphene in an Aqueous Solution with Poly(sodium 4-styrenesulfonate) Monitored by Capillary Electrophoresis, Chromatography, Vol.40, No.3, 121-126, 2019. (徳島大学機関リポジトリ) ● Metadata: 114227 (出版サイトへのリンク) ● Publication site (DOI): 10.15583/jpchrom.2019.016 (文献検索サイトへのリンク) ● CiNii @ 国立情報学研究所 (CRID): 1390564227334986112 ● Search Scopus @ Elsevier (DOI): 10.15583/jpchrom.2019.016 (徳島大学機関リポジトリ: 114227, DOI: 10.15583/jpchrom.2019.016, CiNii: 1390564227334986112)
24.	山田洋平, 鈴田崇仁, 岡田英理子, 髙栁俊夫, 鈴木良尚, 村井啓一郎, 薮谷智規 : タンパク質結晶成長場及びX線回折実験用試料固定材としてのトラックエッチドメンブランフィルターの利用, 分析化学, Vol.68, No.9, 639-646, 2019年. (出版サイトへのリンク) ● Publication site (DOI): 10.2116/bunsekikagaku.68.639 (文献検索サイトへのリンク) ● CiNii @ 国立情報学研究所 (CRID): 1390001277365707776 ● Search Scopus @ Elsevier (DOI): 10.2116/bunsekikagaku.68.639 (DOI: 10.2116/bunsekikagaku.68.639, CiNii: 1390001277365707776)
25.	Toshio Takayanagi, Yuta Becchaku, Yuki Tomiyama, Masashi Kurashina and Hitoshi Mizuguchi : Polyethylene Glycols for the Dispersion Development of Graphene in an Aqueous Surfactant Solution Studied by Affinity Capillary Electrophoresis, Analytical Sciences, Vol.35, No.3, 307-313, 2019. (徳島大学機関リポジトリ) ● Metadata: 114226 (出版サイトへのリンク) ● Publication site (DOI): 10.2116/analsci.18P433 (文献検索サイトへのリンク) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 30416168 ● Summary page in Scopus @ Elsevier: 2-s2.0-85062698396 (徳島大学機関リポジトリ: 114226, DOI: 10.2116/analsci.18P433, PubMed: 30416168, Elsevier: Scopus)
26.	Hitoshi Mizuguchi, Ryota Ishida, Yasushi Kouno, Tadahiko Tachibana, Tomomi Honda, Tatsuro Kijima, Yuhei Yamamoto and Toshio Takayanagi : A Rapid Enrichment Technique for the Ultratrace Determination of Nickel in Water Samples Using a Nanofiber-composite Membrane Filter, Analytical Sciences, Vol.34, No.8, 907-912, 2018. (要約) A new method for the rapid enrichment and highly sensitive determination of nickel ion has been developed by using a nanofiber-composite membrane filter, which was fabricated by stacking a nanofibrous material made of nylon 6 over a water-permeable membrane filter. The noncharged nickel-α-furil dioxime complex was adsorbed on a nanofibrous layer of the membrane filter under significantly higher flow rates than those used for conventional solid-phase extraction techniques. Highly sensitive determinations with detection limits at sub-parts per billion levels were achieved by enrichment from 50 mL of the complex solution, and the enrichment was completed within 3 min. The color that was developed on the membrane filter was successfully subjected to visual colorimetric analysis and quantitative determination by solid-phase spectrophotometry. In addition, colorimetric determination was feasible with a handheld spectrometer after elution of the colored agent with 50 μL of acetone. This combination of rapid enrichment and spectrometric measurement in a small-volume sample provides a useful analytical method suitable for on-site analysis, which requires neither expensive instruments nor high laboratory skills. (出版サイトへのリンク) ● Publication site (DOI): 10.2116/analsci.18P093 (文献検索サイトへのリンク) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 30101885 ● Summary page in Scopus @ Elsevier: 2-s2.0-85064773919 (DOI: 10.2116/analsci.18P093, PubMed: 30101885, Elsevier: Scopus)
27.	Masashi Kurashina, Ikeuchi Daiki, Ohara Masaki, Toshio Takayanagi and Mikito Yasuzawa : Syntheses and properties of copper hydroxide nanosheets and controlled deposition, International Journal of Modern Physics B, Vol.32, No.19, 1840047-1-1840047-5, 2018. (要約) In this study, we synthesized copper hydroxide nanosheet and investigated its electro-chemical property and how to deposit it with a uniform amount. The precursor of the nanosheet was a layered copper hydroxide synthesized by the ion exchange of dodecyl-benzene sulfonate (DBS) with acetate in Cu2(OH)3(CH3COO)·H2O. The nanosheet was prepared by delamination of the layered copper hydroxide by dispersion in 1-butanol. Atomic force microscopy (AFM) images of the nanosheets showed lateral dimensions of ca. 2 μm with the height of ca. 4.5 nm. Cyclic voltammogram of the nanosheet in basic solution showed two cathodic peaks and two anodic peaks similar to the copper oxide electrode. To deposit the nanosheet, a quartz glass slide was dipped in the dispersion of the nanosheet in 1-butanol and dried after washing. This procedure was repeated and the ultraviolet (UV) and visible (Vis) light absorption spectrum of the slide was measured. The absorbance of the slide increased in direct proportion to the number of times of the dip-and-dry procedure. Thus, we confirmed that a controlled amount of nanosheet was deposited on the quartz glass. (徳島大学機関リポジトリ) ● Metadata: 117477 (出版サイトへのリンク) ● Publication site (DOI): 10.1142/S0217979218400477 (文献検索サイトへのリンク) ● Search Scopus @ Elsevier (DOI): 10.1142/S0217979218400477 (徳島大学機関リポジトリ: 117477, DOI: 10.1142/S0217979218400477)
28.	Tomoki Yabutani, Takamasa Nakamura, Toshio Takayanagi and Yohei Yamada : Effect of leaching conditions on the elution of metals from denitration catalyst wastes, International Journal of Modern Physics B, Vol.32, No.19, 1840062-1-1840062-5, 2018. (出版サイトへのリンク) ● Publication site (DOI): 10.1142/S0217979218400623 (文献検索サイトへのリンク) ● Summary page in Scopus @ Elsevier: 2-s2.0-85049354085 (DOI: 10.1142/S0217979218400623, Elsevier: Scopus)
29.	Tomoki Yabutani, Shingo Kishibe, Miki Kamimura, Kosuke Nozoe, Yohei Yamada and Toshio Takayanagi : Copper Speciation for Natural Water by On-site Sample Treatment/Solid-phase Extraction/Inductively Coupled Plasma Mass Spectrometry, Analytical Sciences, Vol.34, No.6, 725-728, 2018. (要約) Herein, we determined the contents of Cu(I), Cu(II), and hydrophobic Cu in natural water using on-site sample treatment, solid-phase extraction (SPE), and inductively coupled plasma mass spectrometry (ICP-MS) analysis. To prevent Cu species changes in the sampling, filtering and preconditioning steps were performed in a closed system using plastic syringes and a disposable membrane filter. Bathocuproin disulfonate (BCS) and ethylenediaminetetraacetic acid (EDTA) were selected as a Cu(I)-selective complexing agent and a Cu(II) masking agent, respectively, whereas ascorbic acid (AA) was used to reduce Cu(II) to Cu(I). Pre-conditioned samples were passed through a hydrophobic SPE column, and the retained Cu species were eluted with ethanol. Subsequently, the eluate was concentrated, and the residue was re-dissolved in 2 M HNO and subjected to ICP-MS analysis. No artificial changes of Cu(I) and Cu(II) species were observed at any time, with the analytical detection limit of total Cu and the blank value equaling 0.0008 and 0.0025 μg kg, respectively. The developed method was applied to real estuarine, riverine, and seawater samples collected in Tokushima prefecture, Japan. (出版サイトへのリンク) ● Publication site (DOI): 10.2116/analsci.18SBP08 (文献検索サイトへのリンク) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 29887562 ● Search Scopus @ Elsevier (PMID): 29887562 ● Search Scopus @ Elsevier (DOI): 10.2116/analsci.18SBP08 (DOI: 10.2116/analsci.18SBP08, PubMed: 29887562)
30.	Toshio Takayanagi, Ikeuchi Kanako and Hitoshi Mizuguchi : Migration Behavior of Carbon Nanotube in Capillary Electrophoresis with Sodium Dodecyl Sulfate and Water-Soluble Nonionic Polymer, Chromatography, Vol.38, No.3, 101-106, 2017. (徳島大学機関リポジトリ) ● Metadata: 114223 (出版サイトへのリンク) ● Publication site (DOI): 10.15583/jpchrom.2017.013 (文献検索サイトへのリンク) ● Search Scopus @ Elsevier (DOI): 10.15583/jpchrom.2017.013 (徳島大学機関リポジトリ: 114223, DOI: 10.15583/jpchrom.2017.013)
31.	Hitoshi Mizuguchi, Keiko Sasaki, Hirokazu Ichinose, Shota Seino, Jun Sakurai, Masamitsu Iiyama, Tatsuro Kijima, Kazuhiro Tachibana, Tatsuo Nishina, Toshio Takayanagi and Junichi Shida : A Triple-Electrode Based Dual-Biosensor System Utilizing Track-Etched Microporous Membrane Electrodes for the Simultaneous Determination of L-Lactate and D-Glucose, Bulletin of the Chemical Society of Japan, Vol.90, No.11, 1211-1216, 2017. (出版サイトへのリンク) ● Publication site (DOI): 10.1246/bcsj.20170193 (文献検索サイトへのリンク) ● Summary page in Scopus @ Elsevier: 2-s2.0-85034619231 (DOI: 10.1246/bcsj.20170193, Elsevier: Scopus)
32.	髙栁俊夫, 磯田昌志, 伊藤大地, 水口仁志 : CZEによる電気泳動移動度測定に基づくヒドロクロロチアジドとその分解生成物の酸解離定数の決定, 分析化学, Vol.66, No.7, 509-514, 2017年. (徳島大学機関リポジトリ) ● Metadata: 114222 (出版サイトへのリンク) ● Publication site (DOI): 10.2116/bunsekikagaku.66.509 (文献検索サイトへのリンク) ● Search Scopus @ Elsevier (DOI): 10.2116/bunsekikagaku.66.509 (徳島大学機関リポジトリ: 114222, DOI: 10.2116/bunsekikagaku.66.509)
33.	水口仁志, 石田亮太, 河野泰志, 橘忠彦, 本田知己, 木島龍朗, 髙栁俊夫 : ナノファイバー複合化メンブランフィルターを用いる微量ヒ素(III)の固相目視比色定量, 分析化学, Vol.66, No.5, 363-368, 2017年. (出版サイトへのリンク) ● Publication site (DOI): 10.2116/bunsekikagaku.66.363 (文献検索サイトへのリンク) ● Search Scopus @ Elsevier (DOI): 10.2116/bunsekikagaku.66.363 (DOI: 10.2116/bunsekikagaku.66.363)
34.	Toshio Takayanagi, Natsumi Shimakami, Masashi Kurashina, Hitoshi Mizuguchi and Tomoki Yabutani : Determination of the Acid-Base Dissociation Constant of Acid-Degradable Hexamethylenetetramine by Capillary Zone Electrophoresis, Analytical Sciences, Vol.32, No.12, 1327-1332, 2016. (要約) The acid-base equilibrium of hexamethylenetetramine (hexamine) was analyzed with its effective electrophoretic mobility by capillary zone electrophoresis. Although hexamine is degradable in a weakly acidic aqueous solution, and the degraded products of ammonia and formaldehyde can be formed, the effective electrophoretic mobility of hexamine was measured in the pH range between 2.8 and 6.9. An acid-base dissociation equilibrium of the protonated hexamine was analyzed based on the mobility change, and an acid dissociation constant of pKa = 4.93 ± 0.01 (mean ± standard error, ionic strength: 0.020 mol dm(-3)) was determined. The monoprotic acid-base equilibrium of hexamine was confirmed through comparisons of its electrophoretic mobility with the N-ethylquinolinium ion and with the monocationic N-ethyl derivative of hexamine, as well as a slope analysis of the dissociation equilibrium. (徳島大学機関リポジトリ) ● Metadata: 114221 (出版サイトへのリンク) ● Publication site (DOI): 10.2116/analsci.32.1327 (文献検索サイトへのリンク) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 27941263 ● Summary page in Scopus @ Elsevier: 2-s2.0-85009453117 (徳島大学機関リポジトリ: 114221, DOI: 10.2116/analsci.32.1327, PubMed: 27941263, Elsevier: Scopus)
35.	Toshio Takayanagi, Daichi Itoh and Hitoshi Mizuguchi : Analysis of Acid Dissociation Equilibrium of Bupropion by Capillary Zone Electrophoresis After the Heat-Degradation, Chromatography, Vol.37, No.3, 105-109, 2016. (徳島大学機関リポジトリ) ● Metadata: 114219 (出版サイトへのリンク) ● Publication site (DOI): 10.15583/jpchrom.2016.009 (文献検索サイトへのリンク) ● Search Scopus @ Elsevier (DOI): 10.15583/jpchrom.2016.009 (徳島大学機関リポジトリ: 114219, DOI: 10.15583/jpchrom.2016.009)
36.	Toshio Takayanagi, Mika AMIYA, Natsumi SHIMAKAMI and Tomoki Yabutani : Determination of Acid Dissociation Constant of Pravastatin under Degraded Conditions by Capillary Zone Electrophoresis, Analytical Sciences, Vol.31, No.11, 1193-1196, 2015. (要約) The acid dissociation constant of pravastatin was determined under degraded conditions. Pravastatin was degraded in an acidic solution (pH = 2.0) for 5 h, and the degradation solution was subjected to the measurement of the effective electrophoretic mobility by capillary zone electrophoresis. Although the amount of pravastatin decreased by the acid degradation, its acid dissociation constant was successfully determined with the residual pravastatin through its effective electrophoretic mobility. The determined acid dissociation constant value agreed well with the one obtained with freshly prepared solution and with some reported values. (出版サイトへのリンク) ● Publication site (DOI): 10.2116/analsci.31.1193 (文献検索サイトへのリンク) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 26561266 ● Summary page in Scopus @ Elsevier: 2-s2.0-84958752568 (DOI: 10.2116/analsci.31.1193, PubMed: 26561266, Elsevier: Scopus)
37.	Kazuhisa Hirabayashi, Kenjiro Hanaoka, Toshio Takayanagi, Yuko Toki, Takahiro Egawa, Mako Kamiya, Toru Komatsu, Tasuku Ueno, Takuya Terai, Kengo Yoshida, Masanobu Uchiyama, Tetsuo Nagano and Yasuteru Urano : Analysis of Chemical Equilibrium of Silicon-Substituted Fluorescein and Its Application to Develop a Scaffold for Red Fluorescent Probes, Analytical Chemistry, Vol.87, No.17, 9061-9069, 2015. (要約) Fluorescein is a representative green fluorophore that has been widely used as a scaffold of practically useful green fluorescent probes. Here, we report synthesis and characterization of a silicon-substituted fluorescein, i.e., 2-COOH TokyoMagenta (2-COOH TM), which is a fluorescein analogue in which the O atom at the 10' position of the xanthene moiety of fluorescein is replaced with a Si atom. This fluorescein analogue forms a spirolactone ring via intramolecular nucleophilic attack of the carboxylic group in a pH-dependent manner. Consequently, 2-COOH TM exhibits characteristic large pH-dependent absorption and fluorescence spectral changes: (1) 2-COOH TM is colorless at acidic pH, whereas fluorescein retains observable absorption and fluorescence even at acidic pH, and the absorption maximum is also shifted; (2) the absorption spectral change occurs above pH 7.0 for 2-COOH TM and below pH 7.0 for fluorescein; (3) 2-COOH TM shows a much sharper pH response than fluorescein because of its pKa inversion, i.e., pKa1 > pKa2. These features are also different from those of a compound without the carboxylic group, 2-Me TokyoMagenta (2-Me TM). Analysis of the chemical equilibrium between pH 3.0 and 11.0 disclosed that 2-COOH TM favors the colorless and nonfluorescent lactone form, compared with fluorescein. Substitution of Cl atoms at the 4' and 5' positions of the xanthene moiety of 2-COOH TM to obtain 2-COOH DCTM shifted the equilibrium so that the new derivative exists predominantly in the strongly fluorescent open form at physiological pH (pH 7.4). To demonstrate the practical utility of 2-COOH DCTM as a novel scaffold for red fluorescent probes, we employed it to develop a probe for β-galactosidase. (出版サイトへのリンク) ● Publication site (DOI): 10.1021/acs.analchem.5b02331 (文献検索サイトへのリンク) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 26237524 ● Summary page in Scopus @ Elsevier: 2-s2.0-84941005822 (DOI: 10.1021/acs.analchem.5b02331, PubMed: 26237524, Elsevier: Scopus)
38.	Watanabe Toshio, Yohei Yamada, Haruhiko Sakuraba, Mikito Yasuzawa, Toshio Takayanagi and Tomoki Yabutani : The hydrophobic effect on electrodeposition of billirubin oxidase CotA, Advanced Materials Research, Vol.1110, 291-294, 2015. (キーワード) electrodeposition / CotA / thiol / self-assembled monolayer / Bio-fuel cells (出版サイトへのリンク) ● Publication site (DOI): 10.4028/www.scientific.net/AMR.1110.291 (文献検索サイトへのリンク) ● Search Scopus @ Elsevier (DOI): 10.4028/www.scientific.net/AMR.1110.291 (DOI: 10.4028/www.scientific.net/AMR.1110.291)
39.	Tomoki Yabutani, Takamasa Nakamura and Toshio Takayanagi : Leaching of metals from steel samples in peracetic acid, Modern Physics Letters. B, Vol.29, No.6&7, 1540038, 2015. (出版サイトへのリンク) ● Publication site (DOI): 10.1142/S0217984915400382 (文献検索サイトへのリンク) ● Summary page in Scopus @ Elsevier: 2-s2.0-84928382924 (DOI: 10.1142/S0217984915400382, Elsevier: Scopus)
40.	髙栁俊夫 : キャピラリーゾーン電気泳動法を活用する副反応進行下での水溶液内平衡反応の解析, 分析化学, Vol.64, No.2, 105-116, 2015年. (要約) キャピラリーゾーン電気泳動法(CZE)による均一水溶液中での平衡反応解析において，CZEの分離の特長を有効に活用する解析手法を開発した．解析の基本となるのはアフィニティキャピラリー電気泳動(ACE)の手法であり，測定対象物質の電気泳動移動度の測定を通して平衡物性を解析する．まず第一に，分離分析により共存物質，分解生成物がCZE分離される点を活用して，易分解性医薬品のハロペリドールの酸解離定数を決定した．さらに，CZE測定時間と同程度の分解反応速度を有する物質は測定中に平衡化学種から徐々に分離されてリーディング/テーリングシグナルとして観測されることに着目し，アルカリ性領域でOH-が付加する副反応を伴うフェノールフタレイン，酸性領域でエステル基の加水分解反応を伴うテトラブロモフェノールフタレインエチルエステルのそれぞれの酸解離定数をACEの手法により決定した．沈殿生成を副反応に伴う平衡反応の解析においては，難溶性物質の溶解度の問題に対して，溶解度までの低濃度ではCZEで通常のシグナルとして観測される特長に加えて，溶解度以上の濃度では生成した沈殿が平衡化学種から分離されて泳動液中で再溶解するために，CZE法では溶解度の問題はある程度許容される特長を見いだした．この特長を活用して，ジピクリルアミネートイオンの水溶液内イオン会合定数，テトラブロモフェノールフタレインの酸解離定数を決定することができた．分離分析法であるCZE法の利用は，一般的な平衡反応の解析手法である均一系における電位差滴定法，光度滴定法等と比較して，分離分析の手法，特長が平衡解析に有効であることを例示した． (キーワード) equilibrium analysis / capillary zone electrophoresis / affinity capillary electrophoresis / side reaction (出版サイトへのリンク) ● Publication site (DOI): 10.2116/bunsekikagaku.64.105 (文献検索サイトへのリンク) ● CiNii @ 国立情報学研究所 (CRID): 1390282679636899200 ● Summary page in Scopus @ Elsevier: 2-s2.0-84924118420 (DOI: 10.2116/bunsekikagaku.64.105, CiNii: 1390282679636899200, Elsevier: Scopus)
41.	Toshio Takayanagi, Genki Inoue and Ayumi Ikuta : Analysis of Binding Equilibrium of Phenylalkylamines to Brij 58 Micelle through the Measurement of Electrophoretic Mobility by CZE, Chromatography, Vol.35, No.3, 147-154, 2014. (出版サイトへのリンク) ● Publication site (DOI): 10.15583/jpchrom.2014.024 (文献検索サイトへのリンク) ● Search Scopus @ Elsevier (DOI): 10.15583/jpchrom.2014.024 (DOI: 10.15583/jpchrom.2014.024)
42.	Tomoki Yabutani, Yuji Inoi, Ayumi Kimura, Yohei Yamada and Toshio Takayanagi : Speciation of Chromium(VI) and Selenium(IV and VI) by High-Performance Liquid Chromatography-Fluorometric Detection Using 2,3-Diaminonaphthalene as a Single Derivatizing Reagent, Bulletin of the Chemical Society of Japan, Vol.87, No.12, 1402-1406, 2014. (要約) A speciation method for chromate, selenite, and selenate was developed by high-performance liquid chromatography (HPLC)-fluorometric detection (FL) using a single derivatizing reagent. Chromium(VI) was determined based on the fluorescence intensity of 1H-naphtho[2,3-d][1,2,3]triazole (NAT) derived from 2,3-diaminonaphthalene (DAN) and nitrous ion; the NO2- was generated through a redox process between Cr(VI) and hydroxylamine hydrochloride (HACl). 4,5-Benzopiazselenol (Se-DAN) was also derived from Se(IV) and DAN, and it was resolved from NAT and detected by reversed-phase HPLC-FL operated under a single setting of an excitation and a fluorescence wavelength. Linear ranges of the calibration curve and detection limits were 0-20 µmol L-1 (correction coefficient: 0.995) and 0.1 µmol L-1 for Cr(VI), and 0-20 µmol L-1 (0.995) and 0.2 µmol L-1 for Se(IV), respectively. Concentration of Se(VI) was estimated from the difference in its concentration between total Se and Se(IV). The analytical procedure for the determination of total Se included a reduction of Se(VI) to Se(IV) with hydrochloric acid and potassium bromide. The linear range of the calibration curve and detection limit for Se(VI) was 0-20 µmol L-1 (correction coefficient: 0.990) and 0.3 µmol L-1, respectively. The proposed method was applied to the determinations of Cr(VI), Se(IV), and Se(VI) in a river water sample. Recoveries of Cr and Se species ranged between 98 and 104%, and the relative standard deviations were about 5% at 10 µmol L-1 levels of the species. (出版サイトへのリンク) ● Publication site (DOI): 10.1246/bcsj.20140109 (文献検索サイトへのリンク) ● CiNii @ 国立情報学研究所 (CRID): 1390282679119116416 ● Search Scopus @ Elsevier (DOI): 10.1246/bcsj.20140109 (DOI: 10.1246/bcsj.20140109, CiNii: 1390282679119116416)
43.	Tomoki Yabutani, Geoffrey Waterhouse, Dongxiao Sun-Waterhouse, James B. Metson, Iinuma Akiko, Le Thi Xuan Thuy, Yohei Yamada, Toshio Takayanagi and Junko Motonaka : Facile synthesis of platinum nanoparticle-containing porous carbons and their application in amperometric glucose biosensing, Mikrochimica Acta, Vol.181, No.5, 1871-1878, 2014. (出版サイトへのリンク) ● Publication site (DOI): 10.1007/s00604-014-1270-1 (文献検索サイトへのリンク) ● Summary page in Scopus @ Elsevier: 2-s2.0-84919329666 (DOI: 10.1007/s00604-014-1270-1, Elsevier: Scopus)
44.	Toshio Takayanagi, Kinuyo Ogura and Tomoki Yabutani : Analysis of Ion-association Equilibrium of Precipitable Dipicrylaminate Ion in Aqueous Solution by Capillary Zone Electrophoresis, Analytical Sciences, Vol.30, No.9, 919-924, 2014. (要約) The ion-association equilibrium of the dipicrylaminate ion (DPA-) was investigated in an aqueous solution with alkali metal ions and with its 18-crown-6 ether complexes as pairing cations by capillary zone electrophoresis (CZE). Although DPA- is precipitable with the pairing cations of K+ and Cs+ in a homogenous aqueous solution, a low concentration of DPA- below its solubility suppressed the formation of the precipitates, and DPA- was detected as a usual CZE signal. Changes in the electrophoretic mobility of DPA- was analyzed for its ion-association equilibrium. The ion association constants determined were almost comparable among alkali metal ions, while the ion association constants were meaningfully large with a hydrophobic 18-crown-6 ether complex of K+. The CZE separation was also proved to be useful for the equilibrium analysis under precipitating conditions. It was suggested that the precipitable property of DPA- with K+ and Cs+ could not be attributed to the ion-association process in an aqueous solution, but to the condensation process concerning the intermolecular CH···O bond in the precipitate crystals, as reported. (キーワード) Dipicrylaminate ion / alkali metal ions / 18-crown-6 ether complexes / ion-association equilibrium / aqueous solution / capillary zone electrophoresis (出版サイトへのリンク) ● Publication site (DOI): 10.2116/analsci.30.919 (文献検索サイトへのリンク) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 25213821 ● CiNii @ 国立情報学研究所 (CRID): 1390001204260604416 ● Summary page in Scopus @ Elsevier: 2-s2.0-84924197693 (DOI: 10.2116/analsci.30.919, PubMed: 25213821, CiNii: 1390001204260604416, Elsevier: Scopus)
45.	島上夏美, 薮谷智規, 髙栁俊夫 : キャピラリーゾーン電気泳動法を用いる電気泳動移動度の測定による光分解性ハロペリドールの酸解離反応解析, 分析化学, Vol.63, No.8, 643-648, 2014年. (キーワード) Haloperidol / 4-(p-chlorophenyl)-4-hydroxypiperidine / capillary zone electrophoresis / acid dissociation constant / degradation (出版サイトへのリンク) ● Publication site (DOI): 10.2116/bunsekikagaku.63.643 (文献検索サイトへのリンク) ● Summary page in Scopus @ Elsevier: 2-s2.0-84908111779 (DOI: 10.2116/bunsekikagaku.63.643, Elsevier: Scopus)
46.	Toshio Takayanagi : Analysis of Fast and Slow Acid Dissociation Equilibria of 3',3'',5',5''-Tetrabromophenolphthalein and Determination of Its Equilibrium Constants by Capillary Zone Electrophoresis, Analytical Sciences, Vol.29, No.11, 1067-1073, 2013. (要約) Acid dissociation constants of 3',3'',5',5''-tetrabrompohenolphthalein (TBPP) were determined in an aqueous solution by capillary zone electrophoresis at an ionic strength of 0.01 mol/L. Two steps of the fast acid-dissociation equilibria including precipitable species of H2TBPP were analyzed at a weakly acidic pH region by using the change in effective electrophoretic mobility of TBPP with the pH of the separation buffer. On the other hand, an acid-dissociation reaction of TBPP at an alkaline pH region was reversible, but very slow to reach its equilibrium; the two TBPP species concerned with the equilibrium were detected as distinct signals in the electropherograms. After reaching its equilibrium, the acid-dissociation constant was determined with the signal height corresponding to its dianion form. Thus, three steps of the acid dissociation constants of TBPP were determined in an aqueous solution as pKa1 = 5.29 ± 0.06, pKa2 = 6.35 ± 0.02, and pKa3 = 11.03 ± 0.04. (出版サイトへのリンク) ● Publication site (DOI): 10.2116/analsci.29.1067 (文献検索サイトへのリンク) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 24212733 ● Search Scopus @ Elsevier (PMID): 24212733 ● Search Scopus @ Elsevier (DOI): 10.2116/analsci.29.1067 (DOI: 10.2116/analsci.29.1067, PubMed: 24212733)
47.	Toshio Takayanagi, Masaki Morimoto and Tomoki Yabutani : Micellar Electrokinetic Chromatography of Graphene and Chemically Modified Graphenes with Dodecylbenzenesulfonate, Analytical Sciences, Vol.29, No.8, 769-771, 2013. (要約) Graphene and chemically modified graphenes were resolved by micellar electrokinetic chromatography (MEKC) using sodium dodecylbenzenesulfonate (SDBS) as a micelle matrix. Graphene was successfully dispersed in a micellar solution, and a consecutive and broad signal was obtained by the MEKC with a 20 mmol dm-³ aqueous SDBS solution for Graphene Nanoplatelets. Chemically oxidized graphene was less retained to the micelle than the Graphene Nanoplatelets by the proposed MEKC, and they were resolved with each other. (キーワード) Graphene / chemically modified graphene / micellar electrokinetic chromatography / dodecylbenzenesulfonate (出版サイトへのリンク) ● Publication site (DOI): 10.2116/analsci.29.769 (文献検索サイトへのリンク) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 23934555 ● CiNii @ 国立情報学研究所 (CRID): 1390001204259106944 ● Search Scopus @ Elsevier (PMID): 23934555 ● Search Scopus @ Elsevier (DOI): 10.2116/analsci.29.769 (DOI: 10.2116/analsci.29.769, PubMed: 23934555, CiNii: 1390001204259106944)
48.	Ye Yin, Toshio Takayanagi, Mitsuko Oshima, Koji Oshita, Shoji Motomizu and Yoshiyuki Murata : Determination of Ultra-Trace Amounts of Lead in River Water by Flow Injection Analysis Coupled with Computer-Controlled Auto-Pretreatment System Using Solid Phase Extraction Procedure, Journal of Flow Injection Analysis, Vol.30, No.1, 45-50, 2013. (キーワード) FIA system / Mini-Column / Solid phase extraction / Analig Pb-01 / Auto-Pretreatment (Auto-Pret) system / Pb(II) / PAR / Spectrophotometry (文献検索サイトへのリンク) ● CiNii @ 国立情報学研究所 (CRID): 1390282763019022208 (CiNii: 1390282763019022208)
49.	G. Inoue, T. Kaneta, Toshio Takayanagi, J. Kakehi, H. Motose and T. Takahashi : Determination of polyamines in Arabidopsis thaliana by capillary electrophoresis using salicylaldehyde-5-sulfonate as a derivatizing reagent, Analytical Methods, Vol.5, No.11, 2854-2859, 2013. (出版サイトへのリンク) ● Publication site (DOI): 10.1039/c3ay26360f (文献検索サイトへのリンク) ● Summary page in Scopus @ Elsevier: 2-s2.0-84878027810 (DOI: 10.1039/c3ay26360f, Elsevier: Scopus)
50.	Toshio Takayanagi, Ayumi Tabara and Takashi Kaneta : Determination of Acid Dissociation Constant of Degradable Tetrabromophenolphthalein Ethyl Ester by Capillary Zone Electrophoresis, Analytical Sciences, Vol.29, No.5, 547-552, 2013. (要約) An acid dissociation constant of tetrabromophenolphthalein ethyl ester (TBPE) was determined through the measurement of electrophoretic mobility by capillary zone electrophoresis (CZE). Although TBPE is degradable in acidic pH region and it gradually degraded at pH conditions around and below its pKa values in the time scale of the CZE measurement, equilibrium species of interest were detected as a peak-shaped signal with tailing of the degraded species. Changes in electrophoretic mobility of the equilibrium species of TBPE were analyzed at its detectable pH range in the presence of phenol red as a mobility standard. An acid dissociation constant of 3.47 ± 0.06 (pK(a), I = 0.01, 25°C, standard error) was determined for TBPE. (出版サイトへのリンク) ● Publication site (DOI): 10.2116/analsci.29.547 (文献検索サイトへのリンク) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 23665628 ● Search Scopus @ Elsevier (PMID): 23665628 ● Search Scopus @ Elsevier (DOI): 10.2116/analsci.29.547 (DOI: 10.2116/analsci.29.547, PubMed: 23665628)
51.	Yohei Yamada, Tetsuya Hayashi, Haruhiko Sakuraba, Tomoki Yabutani and Toshio Takayanagi : Fabrication and characterization of a thermostable quinoprotein aldose sugar dehydrogenase immobilized electrode, Analytical Sciences, Vol.29, No.1, 79-83, 2013. (要約) We fabricated a thermostable quinoprotein aldose sugar dehydrogenase (tPQQ-ASD derived from a hyperthermophilic archaeon Pyrobaculum aerophilum) immobilized electrode. The electrode was prepared by immobilizing agarose gel mixed with the enzyme and carbon nanofiber (CNF) on a carbon paste (CP) electrode containing p-benzoquinone (BQ) as an electron mediator. The electrocatalytic response was clearly observed by the addition of D-glucose at the electrode. The electrode properties such as pH, temperature dependency and substrate selectivity basically followed the enzyme properties. The current response against D-glucose increased with measurement temperatures up to 70°C, and response perturbation caused by dissolved oxygen level was not observed at the electrode. As for the results of long-term stability evaluation, the current response was stable for 30 days when the electrode was stored in HEPES buffer solution (pH 7.0) at 4°C. (キーワード) Benzoquinones / Biosensing Techniques / Buffers / Carbon / Enzyme Stability / Enzymes, Immobilized / Glucose / Glucose Dehydrogenases / Hydrogen-Ion Concentration / Nanofibers / Pyrobaculum / Substrate Specificity / Surface Properties (出版サイトへのリンク) ● Publication site (DOI): 10.2116/analsci.29.79 (文献検索サイトへのリンク) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 23303089 ● Search Scopus @ Elsevier (PMID): 23303089 ● Search Scopus @ Elsevier (DOI): 10.2116/analsci.29.79 (DOI: 10.2116/analsci.29.79, PubMed: 23303089)
52.	髙栁俊夫, 生田愛有美 : キャピラリーゾーン電気泳動法による1-アルキル-3-メチルイミダゾリウムイオンの非イオン界面活性剤ミセルへの結合反応解析, 分析化学, Vol.61, No.7, 649-654, 2012年. (要約) The binding constants (KB) of four kinds of 1-alkyl-3-methylimidazolium ions to nonionic surfactant micelles have been determined through changes in the electrophoretic mobility in capillary zone electrophoresis. Larger binding constants were obtained with much bulky 1-alkyl-3-methylimidazolium ions. A linear free-energy relationship was observed with the KB values against the van der Waals volume of the cations. The KB values obtained with 1-alkyl-3-methylimidazolium ions are almost comparable with a series of N-alkylpyridinium ions previously reported. Both the binding constants and the linear free-energy relationship are smaller than the binding of anionic alkylbenzene sulfonate ions. The results have suggested a weak binding of cations to nonionic surfactant micelles. (キーワード) 1-alkyl-3-methylimidazolium ion / binding constant / nonionic surfactant micelle / capillary zone electrophoresis (出版サイトへのリンク) ● Publication site (DOI): 10.2116/bunsekikagaku.61.649 (文献検索サイトへのリンク) ● CiNii @ 国立情報学研究所 (CRID): 1390001204661140992 ● Search Scopus @ Elsevier (DOI): 10.2116/bunsekikagaku.61.649 (DOI: 10.2116/bunsekikagaku.61.649, CiNii: 1390001204661140992)
53.	Punrat Eakkasit, Chuanuwatanakul Suchada, Chailapakul Orawon, Toshio Takayanagi, Kaneta Takashi and Motomizu Shoji : Determination of Arsenic (III) by Sequential Injection/Anodic Stripping Voltammetry (SI/ASV) Using In-situ Thin Film-Modified Screen-Printed Carbon Electrode (SPCE), Journal of Flow Injection Analysis, Vol.29, No.1, 11-16, 2012. (キーワード) Sequential injection (SI) / Anodic stripping voltammetry (ASV) / Arsenic( ) / Screen-printed carbon electrode (SPCE) / Thin-film modification (文献検索サイトへのリンク) ● CiNii @ 国立情報学研究所 (CRID): 1520009407126160384 (CiNii: 1520009407126160384)
54.	Toshio Takayanagi, Tian-Hua Han, Mitsuko Oshima and Shoji Motomizu : Spectrophotometric Flow Injection Analysis of Chromium(VI) Coupled with On-line Solid-phase Extraction with Anion-exchange Resin Cartridge Column, Journal of Flow Injection Analysis, Vol.28, No.2, 124-129, 2011. (キーワード) Chromium( ) / 1,5-diphenylcarbazide / spectrophotometry / anion-exchange resin / cartridge column / on-line solid-phase extraction (文献検索サイトへのリンク) ● CiNii @ 国立情報学研究所 (CRID): 1520853832090602368 (CiNii: 1520853832090602368)
55.	Mayu Nakaya, Mitsuko Oshima, Toshio Takayanagi, Shoji Motomizu and Hiroki Yamashita : Sensitive fluorimetric flow injection analysis for fluoride ion with a novel reagent, 2',7'-dichlorofluorescein di-tert-butyldimethylsilyl ether, Talanta, Vol.84, No.5, 1361-1365, 2011. (要約) A novel reagent, 2',7'-dichlorofluorescein di-tert-butyldimethylsilyl ether (FCl(2)TBS), was synthesized for fluoride ion and used for a sensitive fluorimetric flow injection analysis by detecting the recovery of fluorescence due to cleavage of Si-O bond. Four kinds of fluorescein di-tert-butyldimethylsilyl ether (FTBS) analogues were synthesized and FCl(2)TBS was the best. By introducing chlorine to FTBS, stability of the reagent, reactivity and the baseline signals were improved. The FIA system was three lines. The sample solution (aqua medium) was injected in the carrier solution (water) and merged with the reagent solution (2.0 × 10(-5)M FCl(2)TBS acetone solution), then mixed with phosphate buffer solution (pH 7.5). The fluorescence intensities were measured at (ex) 503 nm and (em) 527 nm. The calibration graph had linear relationship between (1.0-50.0) × 10(-6)M and the determinable limit was 1.0 × 10(-6)M. The relative standard deviation of 12 measurements with 1.0 × 10(-5)M F(-) solution was 1.0% and the sample throughput was 13 h(-1). The developed method was successfully applied to river and tap water samples. (出版サイトへのリンク) ● Publication site (DOI): 10.1016/j.talanta.2011.03.081 (文献検索サイトへのリンク) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 21641452 ● Search Scopus @ Elsevier (PMID): 21641452 ● Search Scopus @ Elsevier (DOI): 10.1016/j.talanta.2011.03.081 (DOI: 10.1016/j.talanta.2011.03.081, PubMed: 21641452)
56.	Toshio Takayanagi, Kie Hojyo, Fumihiko Iwami and Shoji Motomizu : Determination of Aluminum in Water Samples and Its Speciation Approach by Fluorophotometric Flow Injection Analysis with 8-Quinolinol Coupled with Micelle Sensitization, Journal of Flow Injection Analysis, Vol.27, No.2, 152-157, 2010. (キーワード) Aluminum ion / fluorophotometry / 8-quinolinol / micelle sensitization / speciation analysis (文献検索サイトへのリンク) ● CiNii @ 国立情報学研究所 (CRID): 1390564238017249536 (CiNii: 1390564238017249536)
57.	神﨑啓之, 髙栁俊夫 : ルミノール化学発光を検出法とするシーケンシャルインジェクション分析における錯化剤および界面活性剤の増感効果, 分析化学, Vol.59, No.8, 715-719, 2010年. (要約) Some complexing agents and surfactants sensitize luminol chemiluminescence (CL) with Fe(III) or Fe(II) as a catalyst ; also the effect of the sensitizing reagents on the CL intensity was examined in sequential injection analysis (SIA). Solutions of luminol, H2O2 and a sample solution containing Fe(III) or Fe(II) were sequentially introduced into a holding coil, and the zones of the sucked solutions were immediately propelled to a CL detection cell ; the CL intensity was measured. In the case of the complexing agents as additives, tartrate and oxalate ions in the sample solution were most effective to improve the CL intensity. When surfactants were used as additives, the chemiluminescence was sensitized over the critical micelle concentrations of cationic cetyltrimethylammonium bromide and anionic sodium dodecylsulfate. Sensitization with the complexing agents and the surfactants in SIA are much more effective than in flow injection analysis. Since mixing of the sucked zones is not sufficient in SIA, the chemiluminescence would have been effectively sensitized. (キーワード) chemiluminescence / sequential injection analysis / complexing agents / surfactants / luminol (出版サイトへのリンク) ● Publication site (DOI): 10.2116/bunsekikagaku.59.715 (文献検索サイトへのリンク) ● CiNii @ 国立情報学研究所 (CRID): 1390001204355055360 ● Search Scopus @ Elsevier (DOI): 10.2116/bunsekikagaku.59.715 (DOI: 10.2116/bunsekikagaku.59.715, CiNii: 1390001204355055360)
58.	井上源貴, 髙栁俊夫 : キャピラリーゾーン電気泳動法による18-クラウン-6とフェニルアルキルアンモニウムの錯形成反応の解析, 分析化学, Vol.59, No.8, 709-713, 2010年. (要約) Complex formation equilibrium of phenylalkylammonium ions (PAA+) with 18-crown-6 (18C6) has been analyzed by capillary zone electrophoresis (CZE). The electrophoretic mobility of PAA+ (μep) was measured by CZE in the presence of 18C6 in a migrating buffer, and the μep values were used for equilibrium analysis. The μep values decreased with increasing concentrations of 18C6, and 1 : 1 complex formation constants, K, were determined. The K values for PAA+ in an aqueous solution are comparable to literature data reported for the ammonium ion. The K values increased with a longer alkyl chain in PAA+, except for the benzylammonium ion. The results suggested the contribution of hydrophobicity in PAA+, as well as CH/ϖ interactions for the benzylammonium ion. The K values also increased in mixed aqueous solvents with a decreased dielectric constant, which suggested the contribution of ion-dipole interaction in the complex formation reaction. (キーワード) phenylalkylammonium ions / 18-crown-6 / complex formation equilibrium / capillary zone electrophoresis / intermolecular interactions (出版サイトへのリンク) ● Publication site (DOI): 10.2116/bunsekikagaku.59.709 (文献検索サイトへのリンク) ● CiNii @ 国立情報学研究所 (CRID): 1390282679331765504 ● Search Scopus @ Elsevier (DOI): 10.2116/bunsekikagaku.59.709 (DOI: 10.2116/bunsekikagaku.59.709, CiNii: 1390282679331765504)
59.	Toshio Takayanagi, Ayumi Ikuta and Shoji Motomizu : Weak Binding of N-Alkylpyridinium Ions to Nonionic Surfactant Micelles as Studied by Capillary Zone Electrophoresis, Analytical Sciences, Vol.26, No.5, 625-627, 2010. (要約) The binding equilibrium of N-alkylpyridinium ions to nonionic surfactant micelles was investigated through the changes in the electrophoretic mobility of the alkylpyridinium ions in capillary zone electrophoresis. The binding constants thus determined increased with increasing molecular volume of the alkylpyridinium ions. However, the binding constants are small compared with the ones for the anionic alkylbenzenesulfonate and polynitrophenolate ions at the same molecular volume. (出版サイトへのリンク) ● Publication site (DOI): 10.2116/analsci.26.625 (文献検索サイトへのリンク) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 20467142 ● Search Scopus @ Elsevier (PMID): 20467142 ● Search Scopus @ Elsevier (DOI): 10.2116/analsci.26.625 (DOI: 10.2116/analsci.26.625, PubMed: 20467142)
60.	鈴木保任, 高橋徹, 髙栁俊夫, 本水昌二, 川久保進 : ものづくり教育を指向した簡易比色計及び電位差計キットの開発, 分析化学, Vol.59, No.2, 125-130, 2010年. (要約) 高校生あるいは大学生を対象として，分析機器の組立てを通じてものづくりを体験するとともに，完成した機器が実際の分析に応用できる性能を有するようなキットの開発を目的として，発光ダイオード(LED)を光源とする比色計と，イオン選択性電極と組み合せて使用できる電位差計を開発した．いずれも短時間(2時間以内)かつ安価(1万円以内)で製作できるよう回路を簡略化した．試作した装置を用いて組み立て性と分析性能を評価し，プリント基板を製作した．これらを実際に高校生，高校教員，及び大学生の実習に用いたところ，ほぼ全数が実習時間内に完成し，実用的な性能を有していることを確認できた． (キーワード) LED-base colorimeter / potentiometer / student experiment (出版サイトへのリンク) ● Publication site (DOI): 10.2116/bunsekikagaku.59.125 (文献検索サイトへのリンク) ● CiNii @ 国立情報学研究所 (CRID): 1390282679331874560 ● Search Scopus @ Elsevier (DOI): 10.2116/bunsekikagaku.59.125 (DOI: 10.2116/bunsekikagaku.59.125, CiNii: 1390282679331874560)
61.	Toshio Takayanagi, M. Nishiuchi, M. Ousaka, M. Oshima and S. Motomizu : Monitoring of Vitamin C Species in Aqueous Solution by Flow Injection Analysis Coupled with an On-line Separation with Reversed-phase Column, Talanta, Vol.79, No.4, 1055-1060, 2009. (要約) Two vitamin C species of ascorbic acid and dehydroascorbic acid in aqueous solution were monitored by flow injection analysis. Ascorbic acid and dehydroascorbic acid were resolved by a reversed-phase column, and dehydroascorbic acid was reduced to ascorbic acid by an on-line post-column reaction with dithiothreitol. Both natural and reduced ascorbic acids were photometrically detected at 260 nm, and the two vitamin C species were simultaneously determined. The determination range was from 0 to 8 x 10(-5)M with a limit of detection of 1.7 x 10(-6)M. The proposed method was applied to the conversion monitoring of ascorbic acid and dehydroascorbic acid in weakly acidic to weakly alkaline aqueous solutions, as well as to the determination of the vitamin C in some beverage samples. (キーワード) Air / Ascorbic Acid / Beverages / Calibration / Charcoal / Chromatography, High Pressure Liquid / Dehydroascorbic Acid / Dithiothreitol / Flow Injection Analysis / Kinetics / Nitrogen / Online Systems / Oxidation-Reduction / Reproducibility of Results / Solutions / Spectrophotometry / Time Factors / Water (出版サイトへのリンク) ● Publication site (DOI): 10.1016/j.talanta.2009.02.036 (文献検索サイトへのリンク) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 19615508 ● Search Scopus @ Elsevier (PMID): 19615508 ● Search Scopus @ Elsevier (DOI): 10.1016/j.talanta.2009.02.036 (DOI: 10.1016/j.talanta.2009.02.036, PubMed: 19615508)
62.	Toshio Takayanagi, Y. Inaba, H. Kanzaki, Y. Jyoichi and S. Motomizu : Pre-evaluation of Metal Ions as a Catalyst on Chemiluminometric Sequential Injection Analysis with Luminol-H2O2 System, Talanta, Vol.79, No.4, 1089-1093, 2009. (要約) Catalytic effect of metal ions on luminol chemiluminescence (CL) was investigated by sequential injection analysis (SIA). The SIA system was set up with two solenoid micropumps, an eight-port selection valve, and a photosensor module with a fountain-type chemiluminescence cell. The SIA system was controlled and the CL signals were collected by a LabVIEW program. Aqueous solutions of luminol, H(2)O(2), and a sample solution containing metal ion were sequentially aspirated to the holding coil, and the zones were immediately propelled to the detection cell. After optimizing the parameters using 1 x 10(-5)M Fe(3+) solution, catalytic effect of some metal species was compared. Among 16 metal species examined, relatively strong CL responses were obtained with Fe(3+), Fe(2+), VO(2+), VO(3)(-), MnO(4)(-), Co(2+), and Cu(2+). The limits of detection by the present SIA system were comparable to FIA systems. Permanganate ion showed the highest CL sensitivity among the metal species examined; the calibration graph for MnO(4)(-) was linear at the concentration level of 10(-8)M and the limit of detection for MnO(4)(-) was 4.0 x 10(-10)M (S/N=3). (出版サイトへのリンク) ● Publication site (DOI): 10.1016/j.talanta.2009.03.024 (文献検索サイトへのリンク) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 19615514 ● Search Scopus @ Elsevier (PMID): 19615514 ● Search Scopus @ Elsevier (DOI): 10.1016/j.talanta.2009.03.024 (DOI: 10.1016/j.talanta.2009.03.024, PubMed: 19615514)
63.	K. Oshita, A. Sabarudin, Toshio Takayanagi, M. Oshima and S. Motomizu : Adsorption Behavior of Uranium(VI) and Other Ionic Species on Cross-linked Chitosan Resins Modified with Chelating Moieties, Talanta, Vol.79, No.4, 1031-1035, 2009. (要約) Cross-linked chitosan resins with catechol (catechol-type chitosan, type 1 and type 2), iminodiacetic acid (IDA-type chitosan), iminodimetylphosphonic acid (IDP-type chitosan), phenylarsonic acid (phenylarsonic acid-type chitosan), or serine (serine-type chitosan) were prepared for the collection and concentration of uranium(VI). The adsorption behavior of U(VI) and other ionic species, such as metal ions and oxo-acid ions, on the cross-linked chitosan (base material) and chitosan resins modified with chelating moieties was examined using a column procedure. Especially, the catechol-type chitosan (type 2) adsorbed U(VI) at pH 2-7, and selectively collected U(VI) at acidic pH regions by forming a stable chelate with hydroxyl groups of catechol moiety introduced to the chitosan. Also, the adsorption properties of cationic and anionic species present in aquatic media were elucidated. The adsorption ability for U(VI) was in the order: catechol-type chitosan (type 2)>serine-type chitosan>phenylarsonic acid-type chitosan>the others. The catechol-type chitosan (type 2) was useful for the collection and concentration of uranium(VI). (キーワード) Adsorption / Arsenicals / Catechols / Chelating Agents / Chitosan / Cross-Linking Reagents / Imino Acids / Lanthanoid Series Elements / Phosphonic Acids / Serine / Uranium (出版サイトへのリンク) ● Publication site (DOI): 10.1016/j.talanta.2009.03.035 (文献検索サイトへのリンク) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 19615504 ● Search Scopus @ Elsevier (PMID): 19615504 ● Search Scopus @ Elsevier (DOI): 10.1016/j.talanta.2009.03.035 (DOI: 10.1016/j.talanta.2009.03.035, PubMed: 19615504)
64.	M. Hosoba, K. Oshita, R. K. Katarina, Toshio Takayanagi, M. Oshima and S. Motomizu : Synthesis of novel chitosan resin possessing histidine moiety and its application to the determination of trace silver by ICP-AES coupled with triplet automated-pretreatment system, Analytica Chimica Acta, Vol.639, No.1-2, 51-56, 2009. (要約) A novel chitosan resin, cross-linked chitosan functionalized with histidine moiety (histidine-type chitosan resin), was synthesized for the collection and concentration of trace silver in aquatic samples. A triplet automated-pretreatment system (Triplet Auto-Pret System) installed mini-columns packed with the synthesized histidine-type chitosan resin was coupled with an inductively coupled plasma-atomic emission spectrometry (ICP-AES) for a rapid and sensitive analysis. Adsorption behavior of 50 elements on the histidine-type chitosan resin was examined. A trace amount of Ag(I) was shown a good adsorption in wide pH regions (pH 5-9), and Ag(I) adsorbed was readily recovered with 1 M nitric acid solution. The limit of detection (3sigma) for silver was 0.03 microg L(-1). The system was successfully applied to river water and dipped water in silver coated container. (キーワード) Adsorption / Analytic Sample Preparation Methods / Automation / Chitosan / Environmental Pollutants / Food Packaging / Histidine / Resins, Synthetic / Sensitivity and Specificity / Silver / Spectrophotometry, Atomic / Time Factors / Water (出版サイトへのリンク) ● Publication site (DOI): 10.1016/j.aca.2009.02.050 (文献検索サイトへのリンク) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 19345757 ● Search Scopus @ Elsevier (PMID): 19345757 ● Search Scopus @ Elsevier (DOI): 10.1016/j.aca.2009.02.050 (DOI: 10.1016/j.aca.2009.02.050, PubMed: 19345757)
65.	R. K. Katarina, Toshio Takayanagi, K. Oshita, M. Oshima and S. Motomizu : Sample Pretreatment Using Chitosan-based Chelating Resin for the Determination of Trace Metals in Seawater Samples by Inductively Coupled Plasma-Mass Spectrometry, Analytical Sciences, Vol.24, No.12, 1537-1544, 2008. (要約) A sample-pretreatment method using a chitosan-based chelating resin, ethylenediamine-N,N,N'-triacetate-type chitosan (EDTriA-type chitosan), was developed for the preconcentration of trace metals in seawater and separation of the seawater matrix prior to their determination by inductively coupled plasma-mass spectrometry (ICP-MS). The resin showed very good adsorption for transition metals and rare-earth elements without any interference from alkali and alkaline-earth metals in an acidic media. In the proposed method, an aliquot of a 50-mL sample at pH 4 was used. Metals adsorbed on the resin were eluted using 10 mL of 1 M nitric and measured by ICP-MS. The method was evaluated by the analysis of NASS-5 seawater reference materials for trace metals. Good agreement was obtained for most metals, which indicates that by the proposed pretreatment using the synthesized resin, seawater samples can be favorably measured by ICP-MS. (出版サイトへのリンク) ● Publication site (DOI): 10.2116/analsci.24.1537 (文献検索サイトへのリンク) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 19075461 ● Search Scopus @ Elsevier (PMID): 19075461 ● Search Scopus @ Elsevier (DOI): 10.2116/analsci.24.1537 (DOI: 10.2116/analsci.24.1537, PubMed: 19075461)
66.	K. Oshita, Toshio Takayanagi, M. Oshima and S. Motomizu : Synthesis of Chitosan-Based Resins Functionalized with Serine Moiety and Its Application to Determination of Trace Amounts of Uranium by FI/ICP-MS System, Journal of Flow Injection Analysis, Vol.25, No.1, 73-76, 2008. (キーワード) Chitosan resin / Uranium / Serine / On-line pretreatment / ICP-MS (文献検索サイトへのリンク) ● CiNii @ 国立情報学研究所 (CRID): 1390845713010286464 (CiNii: 1390845713010286464)
67.	K. Oshita, Toshio Takayanagi, M. Oshima and S. Motomizu : Adsorption Properties of Ionic Species on Cross-linked Chitosans Modified with Catechol and Salicylic Acid Moieties, Analytical Sciences, Vol.24, No.5, 665-668, 2008. (要約) Catechol-type chitosan resin and salicylic acid-type chitosan resin were easily synthesized for use in estimating the adsorption behavior of 34 elements at pH 1 - 7 in aquatic media. The catechol-type chitosan resin could adsorb Cu(II) at pH 3 - 7, In(III) at pH 4 - 6, Pb(II) and lanthanoids at pH 5 - 7, and U(VI) at pH 4 - 7 more effectively than the salicylic acid-type chitosan resin and the cross-linked chitosan resin (base material). Adsorption ability was in the order: catechol-type chitosan resin > salicylic acid-type chitosan resin > cross-linked chitosan resin. (キーワード) Adsorption / Catechols / Chitosan / Cross-Linking Reagents / Hydrogen-Ion Concentration / Ions / Mass Spectrometry / Molecular Structure / Salicylic Acid (出版サイトへのリンク) ● Publication site (DOI): 10.2116/analsci.24.665 (文献検索サイトへのリンク) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 18469475 ● Search Scopus @ Elsevier (PMID): 18469475 ● Search Scopus @ Elsevier (DOI): 10.2116/analsci.24.665 (DOI: 10.2116/analsci.24.665, PubMed: 18469475)
68.	K. Oshita, K. Seo, A. Sabarudin, M. Oshima, Toshio Takayanagi and S. Motomizu : Synthesis of Chitosan Resin Possessing a Phenylarsonic Acid Moiety for Collection/Concentration of Uranium and Its Determination by ICP-AES, Analytical and Bioanalytical Chemistry, Vol.390, No.7, 1927-1932, 2008. (要約) A chitosan resin possessing a phenylarsonic acid moiety (phenylarsonic acid type chitosan resin) was developed for the collection and concentration of trace uranium prior to inductively coupled plasma (ICP) atomic emission spectrometry (AES) measurement. The adsorption behavior of 52 elements was systematically examined by packing it in a minicolumn and measuring the elements in the effluent by ICP mass spectrometry. The resin could adsorb several cationic species by a chelating mechanism, and several oxo acids, such as Ti(IV), V(V), Mo(VI), and W(VI), by an anion-exchange mechanism and/or a chelating mechanism. Especially, U(VI) could be adsorbed almost 100% over a wide pH region from pH 4 to 8. Uranium adsorbed was easily eluted with 1 M nitric acid (10 mL), and the 25-fold preconcentration of uranium was achieved by using a proposed column procedure, which could be applied to the determination of trace uranium in seawater by ICP-AES. The limit of detection was 0.1 ng mL(-1) for measurement by ICP-AES coupled with 25-fold column preconcentration. (キーワード) Adsorption / Arsenicals / Chitosan / Molecular Structure / Reproducibility of Results / Resins, Synthetic / Sensitivity and Specificity / Spectrophotometry, Atomic / Time Factors / Uranium (出版サイトへのリンク) ● Publication site (DOI): 10.1007/s00216-008-1931-1 (文献検索サイトへのリンク) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 18278583 ● Search Scopus @ Elsevier (PMID): 18278583 ● Search Scopus @ Elsevier (DOI): 10.1007/s00216-008-1931-1 (DOI: 10.1007/s00216-008-1931-1, PubMed: 18278583)
69.	Toshio Takayanagi, H. Yamashita, S. Motomizu, J. Musijowski and M. Trojanowicz : Preconcentration and Decomposition of Perfluorinated Carboxylic Acids on an Activated Charcoal Cartridge with Sodium Biphenyl Reagent and Its Determination at µg L-1 Level on the Basis of Flow Injection-Fluorimetric Detection of Fluoride Ion, Talanta, Vol.74, No.5, 1224-1230, 2008. (要約) Perfluorinated surfactants of heptafluorobutylate and pentadecafluorooctanoate ions were adsorbed on an activated charcoal cartridge and decomposed with sodium biphenyl (SBP) reagent to form inorganic fluoride ion. The fluoride ion thus formed was determined by flow injection analysis (FIA) using quercetin-Zr complex as a fluorimetric reagent, where lambda(ex) and lambda(em) were 422 and 491 nm, respectively. The limit of detection for fluoride ion by the FIA system was developed to 1.1 x 10(-6)M (signal to noise ratio of three), when 50% (v/v) tetrahydrofuran (THF) was used as a dissolving solvent for quercetin. The perfluorinated surfactants in the sample solution were quantitatively adsorbed on the cartridge containing 100mg of activated charcoal and were decomposed with 0.5 mL of sodium biphenyl reagent after drying thoroughly by flowing through dry nitrogen gas. The fluoride ion formed was recovered with 3 mL of purified water as an eluent, and it was determined by the fluorimetric flow injection system. The blank fluorescence signal accompanied during the adsorption/decomposition on the cartridge was reduced by washing the activated charcoal with acetone. The blank signal was also observed from dimethoxyethane, which was used in sodium biphenyl reagent. When 600 mL sample solution was used and 200 times enrichment was applied, the heptafluorobutylate and pentadecafluorooctanoate ions at the concentrations of 2.1 microg L(-1) were quantitatively recovered as fluoride ion, and the limit of detections for the perfluorinated surfactants were 0.3 and 0.3 microgL(-1) for the two perfluorinated surfactants, respectively (3 sigma of the blank signal). (キーワード) Biphenyl Compounds / Carboxylic Acids / Charcoal / Flow Injection Analysis / Fluorocarbons / Fluorometry / Octanoic Acids / Surface-Active Agents (出版サイトへのリンク) ● Publication site (DOI): 10.1016/j.talanta.2007.08.026 (文献検索サイトへのリンク) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 18371773 ● Search Scopus @ Elsevier (PMID): 18371773 ● Search Scopus @ Elsevier (DOI): 10.1016/j.talanta.2007.08.026 (DOI: 10.1016/j.talanta.2007.08.026, PubMed: 18371773)
70.	K. Oshita, Toshio Takayanagi, M. Oshima and S. Motomizu : Adsorption Behavior of Cationic and Anionic Species on Chitosan Resins Possessing Amino Acid Moieties, Analytical Sciences, Vol.23, No.12, 1431-1434, 2007. (要約) Chitosan resins modified with amino acids, such as glycine, valine, leucine, and serine, were synthesized for investigating the adsorption behavior of cationic and anionic species, and showed good abilities for the adsorption of trace elements in aquatic media as follows: glycine for lanthanoids at pH 7, leucine for molybdenum at pH 1-5, serine for uranium at pH 2-7, and amino acids for bismuth at pH 1-7. Cationic and anionic species could be adsorbed by a chelating mechanism and an anion-exchange mechanism. (キーワード) Actinoid Series Elements / Adsorption / Amino Acids / Anions / Cations / Chelating Agents / Chitosan / Cross-Linking Reagents / Hydrogen-Ion Concentration / Indicators and Reagents / Lanthanoid Series Elements / Mass Spectrometry / Resins, Synthetic (出版サイトへのリンク) ● Publication site (DOI): 10.2116/analsci.23.1431 (文献検索サイトへのリンク) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 18071231 ● Search Scopus @ Elsevier (PMID): 18071231 ● Search Scopus @ Elsevier (DOI): 10.2116/analsci.23.1431 (DOI: 10.2116/analsci.23.1431, PubMed: 18071231)
71.	J. Musijowski, M. Trojanowicz, B. Szostek, J. C. F. L. Lima, R. Lapa, H. Yamashita, Toshio Takayanagi and S. Motomizu : Flow-Injection Determination of Total Organic Fluorine with Off-line Defluorination Reaction on a Solid Sorbent Bed, Analytica Chimica Acta, Vol.600, No.1-2, 147-154, 2007. (要約) Considering recent reports on widespread occurrence and concerns about perfluoroalkyl substances (PFAS) in environmental and biological systems, analysis of these compounds have gained much attention in recent years. Majority of analyte-specific methods are based on a LC/MS/MS or a GC/MS detection, however many environmental or biological studies would benefit from a total organic fluorine (TOF) determination. Presented work was aimed at developing a method for TOF determination. TOF is determined as an amount of inorganic fluoride obtained after defluorination reaction conducted off-line using sodium biphenyl reagent directly on the sorbent without elution of retained analytes. Recovered fluoride was analyzed using flow-injection system with either fluorimetric or potentiometric detection. The TOF method was tested using perfluorocarboxylic acids (PFCA), including perfluorooctanoic acid (PFOA), as model compounds. Considering low concentrations of PFAS in natural samples, solid-phase extraction as a preconcentration procedure was evaluated. Several carbon-based sorbents were tested, namely multi-wall carbon nanotubes, carbon nanofibres and activated carbon. Good sorption of all analytes was achieved and defluorination reaction was possible to carry out directly on a sorbent bed. Recoveries obtained for PFCAs, adsorbed on an activated carbon sorbent, and measured as TOF, were 99.5+/-1.7, 110+/-9.4, 95+/-26, 120+/-32, 110+/-12 for C4, C6, C8, C10 and C12-PFCA, respectively. Two flow systems that would enable the defluorination reaction and fluoride determination in a single system were designed and tested. (キーワード) Carbon / Flow Injection Analysis / Fluorine / Online Systems / Organic Chemicals (出版サイトへのリンク) ● Publication site (DOI): 10.1016/j.aca.2007.03.068 (文献検索サイトへのリンク) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 17903477 ● Search Scopus @ Elsevier (PMID): 17903477 ● Search Scopus @ Elsevier (DOI): 10.1016/j.aca.2007.03.068 (DOI: 10.1016/j.aca.2007.03.068, PubMed: 17903477)
72.	A. Sabarudin, N. Lenghor, M. Oshima, L. Hakim, Toshio Takayanagi, Y.-H. Gao and S. Motomizu : Sequential-Injection On-line Preconcentration Using Chitosan Resin Functionalized with 2-Amino-5-hydroxy Benzoic Acid for the Determination of Trace Elements in Environmental Water Samples by Inductively Coupled Plasma-Atomic Emission Spectrometry, Talanta, Vol.72, No.5, 1609-1617, 2007. (要約) A new chelating resin using chitosan as a base material was synthesized. Functional moiety of 2-amino-5-hydroxy benzoic acid (AHBA) was chemically bonded to the amino group of cross-linked chitosan (CCTS) through the arm of chloromethyloxirane (CCTS-AHBA resin). Several elements, such as Ag, Be, Cd, Co, Cu, Ni, Pb, U, V, and rare earth elements (REEs), could be adsorbed on the resin. To use the resin for on-line pretreatment, the resin was packed in a mini-column and installed into a sequential-injection/automated pretreatment system (Auto-Pret System) coupled with inductively coupled plasma-atomic emission spectrometry (ICP-AES). The sequential-injection/automated pretreatment system was a laboratory-assembled, and the program was written using Visual Basic software. This system can provide easy operation procedures, less reagent consumption, as well as less waste production. Experimental variables considered as effective factors in the improvement sensitivity, such as an eluent concentration, a sample and an eluent flow rate, pH of samples, and air-sandwiched eluent were carefully optimized. The proposed system provides excellent on-line collection efficiency, as well as high concentration factors of analytes in water samples, which results in highly sensitive detection of ultra-trace and trace analysis. Under the optimal conditions, the detection limits of 24 elements examined are in the range from ppt to sub-ppb levels. The proposed method was validated by using the standard reference material of a river water, SLRS-4, and the applicability was further demonstrated to the on-line collection/concentration of trace elements, such as Ag, Be, Cd, Co, Cu, Ni, Pb, U, V, and REEs in water samples. (出版サイトへのリンク) ● Publication site (DOI): 10.1016/j.talanta.2007.01.024 (文献検索サイトへのリンク) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 19071805 ● Search Scopus @ Elsevier (PMID): 19071805 ● Search Scopus @ Elsevier (DOI): 10.1016/j.talanta.2007.01.024 (DOI: 10.1016/j.talanta.2007.01.024, PubMed: 19071805)
73.	Toshio Takayanagi and S. Motomizu : Pseudo-Homogeneous Micelle Extraction of Ion-Associates Formed between Tetrabutylammonium Ion and Some Aromatic Sulfonate Ions into Nonionic Surfactant Micelle Studied through the Mobility Measurements in Capillary Zone Electrophoresis, Journal of Chromatography. A, Vol.1141, No.2, 295-301, 2007. (要約) Ion-association extraction of some aromatic sulfonate ions including alkylbenzene sulfonates with tetrabutylammonium ion (TBA+) into nonionic surfactant micelle has been investigated through the changes in the electrophoretic mobility. Nonionic surfactants of Brij 35 and Brij 58 were used as micelle substrates to which the ion-associates formed could distribute. The electrophoretic mobility of the aromatic sulfonate ions was measured by capillary zone electrophoresis in the presence of TBA+ and/or the nonionic surfactant to determine ion-association constants (K(ass)), binding constants of the anions to the nonionic surfactant micelle (K(B)), and binding constants of the ion-associates to the nonionic surfactant micelle (K(B,IA)). Nonlinear phenomena induced with the alkyl chain moiety were observed on K(ass) and K(B) by its linear structure and the mixed micelle formation, respectively. Larger K(B) values were obtained with Brij 58 as micelle matrix than with Brij 35, while the differences in K(B,IA) were small between Brij 58 and Brij 35. (キーワード) Electrophoresis, Capillary / Micelles / Quaternary Ammonium Compounds / Sulfonic Acids / Surface-Active Agents (出版サイトへのリンク) ● Publication site (DOI): 10.1016/j.chroma.2006.12.034 (文献検索サイトへのリンク) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 17207490 ● Search Scopus @ Elsevier (PMID): 17207490 ● Search Scopus @ Elsevier (DOI): 10.1016/j.chroma.2006.12.034 (DOI: 10.1016/j.chroma.2006.12.034, PubMed: 17207490)
74.	Toshio Takayanagi and S. Motomizu : Ion-Association Extraction of Nitrobenzoate Ions with Tetrabutylammonium Ion into Nonionic Surfactant Micelles as Studied by Capillary Zone Electrophoresis, Bulletin of the Chemical Society of Japan, Vol.80, No.1, 183-188, 2007. (出版サイトへのリンク) ● Publication site (DOI): 10.1246/bcsj.80.183 (文献検索サイトへのリンク) ● CiNii @ 国立情報学研究所 (CRID): 1390282679119936640 ● Search Scopus @ Elsevier (DOI): 10.1246/bcsj.80.183 (DOI: 10.1246/bcsj.80.183, CiNii: 1390282679119936640)
75.	A. Sabarudin, M. Oshima, Toshio Takayanagi, L. Hakim, K. Oshita, Y.-H. Gao and S. Motomizu : Functionalization of Chitosan with 3,4-Dihydroxybenzoic Acid for the Adsorption/Collection of Uranium in Water Samples and Its Determination by Inductively Coupled Plasma-Mass Spectrometry, Analytica Chimica Acta, Vol.581, No.2, 214-220, 2007. (要約) A chitosan resin derivatized with 3,4-dihydroxybenzoic acid moiety (CCTS-DHBA resin) was newly synthesized for the collection/concentration of trace uranium by using cross-linked chitosan (CCTS) as base material, and the adsorption behavior of uranium as well as 60 elements on the resin was examined by passing the sample solutions through a mini-column packed with the resin. After the elution of the collected elements on the resin with 1M HNO(3), the eluates were measured by inductively coupled plasma-mass spectrometry (ICP-MS). The CCTS-DHBA resin can adsorb several metal cations and several oxoanionic elements at appropriate pH. Among these metal ions, uranium shows an excellent adsorption behavior on this resin. Uranium as UO(2)(2+) species can be adsorbed on the resin by chelating mechanism with adsorption capacity of 330 mg g(-1) resin. Through the column treatment, the complete removal of large amounts of alkali and alkaline earth matrices without any loss of adsorption efficiency over prolonged usage were achieved with this resin. The CCTS-DHBA resin was applied to the adsorption/collection of uranium in tap water, river water and seawater samples with satisfactory results. The validation of the proposed method was carried out by analyzing uranium in the standard reference materials of SLRS-4, CASS-4, and NASS-5 after passing through the CCTS-DHBA resin, and the results showed good agreement with the certified values. (出版サイトへのリンク) ● Publication site (DOI): 10.1016/j.aca.2006.08.024 (文献検索サイトへのリンク) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 17386447 ● Search Scopus @ Elsevier (PMID): 17386447 ● Search Scopus @ Elsevier (DOI): 10.1016/j.aca.2006.08.024 (DOI: 10.1016/j.aca.2006.08.024, PubMed: 17386447)
76.	Toshio Takayanagi and S. Motomizu : Ion-Association Extraction of Nitrophenolate Ions with Tetrabutylammonium Ion into Nonionic Surfactant Micelle, Journal of Chromatography. A, Vol.1133, No.1-2, 353-360, 2006. (要約) Ion-association extraction of some nitrophenolate ions with tetrabutylammonium ion (TBA(+)) into nonionic surfactant micelle has been investigated through the changes in the electrophoretic mobility. Nonionic surfactants of Brij 35 and Brij 58 were used as micelle substrates to which the ion-associates formed could distribute. The electrophoretic mobility of the phenolate ions was measured by capillary zone electrophoresis in the presence of TBA(+) and/or the nonionic surfactant. The electrophoretic mobility of the analyte anions decreased with increasing concentrations of the interacting reagent. Ion association constants (K(ass)) between TBA(+) and the phenolate ions, as well as binding constants of the anions to the nonionic surfactant micelle (K(B)), were determined through the mobility change by applying it to a non-linear least-squares analysis. Binding of the ion-associates was also observed from the aqueous phase to the micelle phase, when both TBA(+) and the nonionic surfactant are present. Binding constants of the ion-associates to the nonionic surfactant micelle (K(B,IA)), as well as micelle extraction constants of the ion-associates (K(ex,m)), were also determined by using the mobility change. The K(ex,m) values obtained were compared with the ion association-solvent extraction constants (K(ex,S)) between water and chloroform. (キーワード) Electrophoresis, Capillary / Micelles / Models, Chemical / Quaternary Ammonium Compounds / Surface-Active Agents (出版サイトへのリンク) ● Publication site (DOI): 10.1016/j.chroma.2006.08.036 (文献検索サイトへのリンク) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 16938302 ● Search Scopus @ Elsevier (PMID): 16938302 ● Search Scopus @ Elsevier (DOI): 10.1016/j.chroma.2006.08.036 (DOI: 10.1016/j.chroma.2006.08.036, PubMed: 16938302)
77.	K. Uraisin, Toshio Takayanagi, D. Nacapricha and S. Motomizu : Novel Oxidation Reaction of Prochlorperazine with Bromate in the Presence of Synergistic Activators and Its Application to Trace Determination by Flow Injection/Spectrophotometric Method, Analytica Chimica Acta, Vol.580, No.1, 68-75, 2006. (要約) A simple and fast flow injection spectrophotometric method for the determination of bromate in water samples was developed. The detection system is based on the oxidation of prochlorperazine (PCP) with bromate in strongly acidic medium. Large amounts of chloride and bromide was found, for the first time, to act as an activator, and to enhance the sensitivity for bromate detection. The oxidation product of PCP gives pink color, which can be used to monitor the reaction spectrophotometrically at 525 nm. Under the optimal conditions, the method is selective; only nitrite, chlorite and hypochlorite can interfere with the determination of bromate. The elimination of these three ions is discussed. The calibration graph for bromate determination was linear in the range of 10-130 microg L(-1) with a detection limit of 2.3 microg L(-1). The repeatability was satisfactory, with the relative standard deviation of 1.1% (25 microg L(-1), n=10). The sample throughput was 44 h(-1). The proposed method was found to be highly reliable for screening drinking waters containing bromate, which is above or below legislation limit of 10 microg L(-1). (出版サイトへのリンク) ● Publication site (DOI): 10.1016/j.aca.2006.07.045 (文献検索サイトへのリンク) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 17723757 ● Search Scopus @ Elsevier (PMID): 17723757 ● Search Scopus @ Elsevier (DOI): 10.1016/j.aca.2006.07.045 (DOI: 10.1016/j.aca.2006.07.045, PubMed: 17723757)
78.	山本貴子, A. Sabarudin, 野口修, 髙栁俊夫, 大島光子, 本水昌二 : 誘導結合プラズマ発光分析のためのキレート樹脂を用いる高効率自動前処理濃縮, 分析化学, Vol.55, No.9, 715-720, 2006年. (要約) 誘導結合プラズマ発光分析法(ICP-AES)のための自動捕集濃縮前処理法を開発した.元素の捕集濃縮にはイミノ二酢酸基をもつキレートディスクとキレート樹脂を用い,これらを市販のラインフィルターに詰め込んで捕集濃縮カラムを作製し,自動捕集濃縮装置のバルブに接続して用いた.自動輔集濃縮装置はコンピュータで制御可能であり,キレート樹脂のコンディショニングを2分間,元素捕集を5分間,洗浄を1分間,溶離を1分間で処理し,流量は1ml min^<-1>で行った.自動捕集濃縮装置はオンラインでICP-AESに接続した.試料溶液から各元素をpH5.5で捕集し,2M硝酸で溶離を行い,ビスマス,カドミウム,コバルト,クロム,銅,マンガン,ニッケル,鉛,バナジウムの9元素が同時定量可能であった.5mlの試料溶液を用いたときの濃縮倍率は3∼15倍程度であり,捕集率は低い場合でも約80%であった.検出下限は,最もよいマンガンで0.003ppb,最も悪いビスマスで0.31ppbであり,捕集濃縮をしない通常の測定に比べ数10∼100倍高感度となった.本法を水道水及び河川水中のこれらの微量元素の定量に応用したところ,良好な結果を得た. (キーワード) automated collection / concentration / chelating disk and chelating resin / ICP-AES / heavy metals (出版サイトへのリンク) ● Publication site (DOI): 10.2116/bunsekikagaku.55.715 (文献検索サイトへのリンク) ● CiNii @ 国立情報学研究所 (CRID): 1390282679331362944 ● Search Scopus @ Elsevier (DOI): 10.2116/bunsekikagaku.55.715 (DOI: 10.2116/bunsekikagaku.55.715, CiNii: 1390282679331362944)
79.	城市康隆, N. Lenghor, 髙栁俊夫, 大島光子, 本水昌二, 浦信夫 : コンピュータ制御されたフローインジェクション分析装置の開発と環境水中の硝酸イオン，亜硝酸イオン，アンモニウムイオン定量への応用, 分析化学, Vol.55, No.9, 707-713, 2006年. (要約) 低電力でパーソナルコンピュータによる制御が可能なフローインジェクション分析装置の開発を目的として,ソレノイドポンプと発光ダイオード(LED)検出器を用いるシステムを構築し,LabVIEWを用いて装置制御とデータ取り込みを行うプログラムを組み上げた.このフローインジェクションシステムを用いる分析法として,ジアゾ化カップリング反応に基づく河川水中の亜硝酸イオンの定量に適用した.各種ポンプと検出器の組み合わせにおいて,亜硝酸イオンの検量線は0.5∼3.0×10^<-6>M範囲で良好な直線性が得られた.また,Cd/Cu還元カラムを用いる亜硝酸イオンと硝酸イオンの分析ではバイパス流路への分岐と遅延により,両者を分別して定量することができた.インドフェノール法に基づく河川水中アンモニアの定量にも適用し,窒素分析を目的とする環境試料に適用可能であることを示した. (キーワード) Flow injection analysis / LabVIEW control / solenoid pumps / nitrate ion / nitrite ion / ammonia (出版サイトへのリンク) ● Publication site (DOI): 10.2116/bunsekikagaku.55.707 (文献検索サイトへのリンク) ● CiNii @ 国立情報学研究所 (CRID): 1390001204354652160 ● Search Scopus @ Elsevier (DOI): 10.2116/bunsekikagaku.55.707 (DOI: 10.2116/bunsekikagaku.55.707, CiNii: 1390001204354652160)
80.	Toshio Takayanagi and S. Motomizu : Chitosan as Cationic Polyelectrolyte for the Modification of Electroosmotic Flow and Its Utilization for the Separation of Inorganic Anions by Capillary Zone Electrophoresis, Analytical Sciences, Vol.22, No.9, 1241-1244, 2006. (要約) Cationic polyelectrolyte of chitosan was used for the reversal of electroosmotic flow in capillary zone electrophoresis. The chitosan was dissolved in acetic acid solution, and stable electroosmotic flow was obtained at the chitosan concentrations between 50 and 300 microg/mL. Separation of inorganic anions was carried out using the dynamically coated capillary by capillary zone electrophoresis. Nine kinds of anions were separated and detected with the capillary. The electrophoretic mobility of the analyte anions decreased with increasing concentrations of chitosan in the migrating solution through ion-ion interaction, but the migration order of the analyte anions was not changed in the concentration range of the chitosan examined. The signal shape for the analyte anions was developed by using field-enhanced sample stacking with 10 mM sodium sulfate. (出版サイトへのリンク) ● Publication site (DOI): 10.2116/analsci.22.1241 (文献検索サイトへのリンク) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 16966817 ● Search Scopus @ Elsevier (PMID): 16966817 ● Search Scopus @ Elsevier (DOI): 10.2116/analsci.22.1241 (DOI: 10.2116/analsci.22.1241, PubMed: 16966817)
81.	R. Driouich, Toshio Takayanagi, M. Oshima and S. Motomizu : Synthesis of Water-Soluble Phenylazosalicylaldehyde Analogues and Their Application to Capillary Electrophoretic Determination of Primary Amines, Electrophoresis, Vol.27, No.17, 3460-3466, 2006. (要約) Several primary amines are known to be endogenous substances, and they are to be detected at very low concentration level. Novel water-soluble azo dyes as precolumn derivatizing reagents were synthesized for the analysis of primary amines with strong visible-light absorption by CZE. A coupling reaction was used to introduce a sulfophenylazo group to salicylaldehyde or 1-hydroxy-2-naphthaldehyde to extend the conjugation and to improve the solubility in water of the derivatizing reagents, as well as the target compounds of the reaction products with the primary amines. Two azo dyes of 5-(4-sulfophenylazo)salicylaldehyde sodium salt (AZO1) and 4-(4-sulfophenylazo)-1-hydroxy-2-naphthaldehyde sodium salt (AZO2) were synthesized. Separation of eight kinds of n-alkylamines was performed by CZE after the derivatization with AZO1 or AZO2. The addition of Brij 35 to the running electrolyte and to the sample solutions was necessary to improve the solubility and the resolution among the analytes. Both reagents, AZO1 and AZO2, were compared with each other in terms of the reaction time of derivatization, the detection sensitivity and the total analysis time. The derivatization process using AZO2 was applied to the determination of four biogenic amines, histamine, tyramine, cadaverine and putrescine, and LODs at around micromolar level were achieved for the four amines. (キーワード) Aldehydes / Amines / Azo Compounds / Biogenic Amines / Electrophoresis, Capillary / Kinetics / Reproducibility of Results / Sensitivity and Specificity / Solubility / Water (出版サイトへのリンク) ● Publication site (DOI): 10.1002/elps.200600320 (文献検索サイトへのリンク) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 16888712 ● Search Scopus @ Elsevier (PMID): 16888712 ● Search Scopus @ Elsevier (DOI): 10.1002/elps.200600320 (DOI: 10.1002/elps.200600320, PubMed: 16888712)
82.	Toshio Takayanagi, M. Ishida, J. Mbuna, R. Driouich and S. Motomizu : Determination of Bromate Ion in Drinking Water by Capillary Zone Electrophoresis with Direct Photometric Detection, Journal of Chromatography. A, Vol.1128, No.1-2, 298-302, 2006. (要約) Bromate ion in drinking water was determined by capillary zone electrophoresis (CZE) with direct photometric detection. Bromate ion in the sample solution was introduced and concentrated into the capillary by electrokinetic injection for 50s at -10 kV. Electrophoretic separation was made at an applied voltage of -25 kV and bromate ion was detected at wavelength 193 nm, at which the baseline was stabilized with less UV-absorbing acidic phosphate buffer. Bromate ion was detected within 5 min in the electropherogram. By increasing the electric conductivity in the migrating solution with 10 mM Na2SO4, a limit of detection (LOD) of 9 x 10(-10)M (0.1 microg/L BrO3-) was achieved. The proposed method was applied to the analysis of tap water and river water samples, but bromate ion was not detected. Because the practical samples contain relatively large amount of foreign ionic substances, the tap water sample was diluted to avoid the matrix ions. Bromate ion added in a tap water at the concentration of 8 x 10(-8)M was quantitatively recovered by diluting it 1/10. (キーワード) Bromates / Buffers / Calibration / Electrophoresis, Capillary / Fresh Water / Spectrophotometry, Ultraviolet / Water Supply (出版サイトへのリンク) ● Publication site (DOI): 10.1016/j.chroma.2006.06.056 (文献検索サイトへのリンク) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 16820157 ● Search Scopus @ Elsevier (PMID): 16820157 ● Search Scopus @ Elsevier (DOI): 10.1016/j.chroma.2006.06.056 (DOI: 10.1016/j.chroma.2006.06.056, PubMed: 16820157)
83.	S. Lunvongsa, Toshio Takayanagi, M. Oshima and S. Motomizu : Novel Catalytic Oxidative Coupling Reaction of N,N-Dimethyl-p-phenylenediamine with 1,3-Phenylenediamine and Its Applications to the Determination of Copper and Iron at Trace Levels by Flow Injection Technique, Analytica Chimica Acta, Vol.576, No.2, 261-269, 2006. (要約) A new catalytic oxidative coupling reaction of N,N-dimethyl-p-phenylenediamine (DPD) with 1,3-phenylenediamine (mPD) in the presence of hydrogen peroxide has been developed for trace metals analysis. The rate of the oxidation/coupling reaction can be enhanced significantly by iron, copper and cobalt. These metal ions can catalyze the oxidation reaction of DPD to form an oxidized product; the oxidized DPD was then coupled with mPD to give a blue-colored product which was measured spectrophotometrically at 650 nm. On the basis of such a reaction scheme, two simple flow injection analysis methods for the determination of copper and iron have been developed. Detailed studies on chemical and FIA variables affecting the sensitivity of the detection were carried out. Interferences from several ionic species were examined for the determination of copper: the interference effect by Fe(III) and Fe(II) up to 1.5 mg L(-1) was successfully suppressed by pretreating sample with ammonium acetate buffer solution (pH 8.4). Good linearity of a standard calibration graph was obtained over the ranges of 0-8 and 0-2 microg L(-1) of copper and iron, respectively, and the detection limits were 0.05 and 0.02 microg L(-1) for copper and iron, respectively. The precision of the methods in terms of relative standard deviation were 1.4 and 1.5% of R.S.D. which were obtained from 10 injections of 2.0 and 1.0 microg L(-1) of standard copper and iron, respectively. The proposed methods were successfully applied to the determination of copper and iron in tap and river water samples. The accuracy of the proposed methods was assessed by the analysis of certified reference material of river water. (出版サイトへのリンク) ● Publication site (DOI): 10.1016/j.aca.2006.06.011 (文献検索サイトへのリンク) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 17723641 ● Search Scopus @ Elsevier (PMID): 17723641 ● Search Scopus @ Elsevier (DOI): 10.1016/j.aca.2006.06.011 (DOI: 10.1016/j.aca.2006.06.011, PubMed: 17723641)
84.	K. Uraisin, Toshio Takayanagi, M. Oshima, D. Nacapricha and S. Motomizu : Simple and Highly Sensitive Spectrophotometric Flow Injection Method for the Determination of Iodate in Iodized Salt, Journal of Flow Injection Analysis, Vol.23, No.1, 13-18, 2006. (キーワード) spectrophotometry / prochlorperazine / iodate / iodized salt (文献検索サイトへのリンク) ● CiNii @ 国立情報学研究所 (CRID): 1520853832983910400 (CiNii: 1520853832983910400)
85.	R. K. Katarina, Toshio Takayanagi, M. Oshima and S. Motomizu : Synthesis of a Chitosan-Based Chelating Resin and Its Application to the Selective Concentration and Ultratrace Determination of Silver in Environmental Water Samples, Analytica Chimica Acta, Vol.558, No.1-2, 246-253, 2006. (出版サイトへのリンク) ● Publication site (DOI): 10.1016/j.aca.2005.11.010 (文献検索サイトへのリンク) ● Search Scopus @ Elsevier (DOI): 10.1016/j.aca.2005.11.010 (DOI: 10.1016/j.aca.2005.11.010)
86.	K. Uraisin, Toshio Takayanagi, M. Oshima, D. Nacapricha and S. Motomizu : Kinetic-Spectrophotometric Method for the Determination of Trace Amounts of Bromide in Seawater, Talanta, Vol.68, No.3, 951-956, 2006. (要約) A novel simple, sensitive and rapid kinetic-spectrophotometric method is proposed for the determination of trace amounts of bromide. The method is based on its catalytic effect on the oxidation of methylene blue (MB) by hydrogen peroxide in strongly acidic solution. The oxidation reaction is activated by large amounts of chloride and can be monitored spectrophotometrically by measuring the decrease in the absorbance of MB at 746 nm. The determination of bromide is performed by a fixed-time method at the first 100 s from the initiation of the reaction. Unlike other kinetic-spectrophotometric methods for the determination of bromide, the proposed method does not require heating the solution. Bromide can be determined in the range from 80 to 960 microg l(-1) with the detection limit of 35 microg l(-1). The relative standard deviation of ten replicate determination of 480 microg l(-1) bromide was 1.4%. The influence of potential interfering ions was studied. The proposed method was satisfactorily applied to the determination of bromide in seawater without interfering effect from chloride ion. (出版サイトへのリンク) ● Publication site (DOI): 10.1016/j.talanta.2005.06.061 (文献検索サイトへのリンク) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 18970415 ● Summary page in Scopus @ Elsevier: 2-s2.0-30144445322 (DOI: 10.1016/j.talanta.2005.06.061, PubMed: 18970415, Elsevier: Scopus)
87.	Y. Kubozono, T. Nagano, Y. Haruyama, E. Kuwahara, Toshio Takayanagi, K. Ochi and A. Fujiwara : Fabrication of C₆₀ Field-Effect Transistors with Polyimide and Ba_0.4Sr_0.6Ti_0.96O₃ Gate Insulators, Applied Physics Letters, Vol.87, No.14, 143506, 2005. (要約) A flexible C_<60> field-effect transistor (FET) device has been fabricated with a polyimide gate insulator on the poly(ethylene terephthalate) substrate, and n-channel normally off FET properties are observed in this FET device. The field-effect mobility, μ, is estimated to be ~10^<-2> cm^2 V^<-1> s^<-1> at 300 K. Furthermore, the C_<60> FET has been fabricated with a high-dielectric Ba_<0.4>Sr_<0.6>Ti_<0.96>O_3(BST) gate insulator, showing n-channel properties; the μ value is estimated to be ~10^<-4> cm^2 V^<-1> s^<-1> at 300 K. The FET device operates at very low gate voltage, V_G, and low drain-source voltage, V_<DS>. Thus these C_<60> FET devices possess flexibility and low-voltage operation characteristic of polyimide and BST gate insulators, respectively. (出版サイトへのリンク) ● Publication site (DOI): 10.1063/1.2081134 (文献検索サイトへのリンク) ● CiNii @ 国立情報学研究所 (CRID): 1050282812513697664 ● Search Scopus @ Elsevier (DOI): 10.1063/1.2081134 (DOI: 10.1063/1.2081134, CiNii: 1050282812513697664)
88.	E. Kuwahara, H. Kusai, T. Nagano, Toshio Takayanagi and Y. Kubozono : Fabrication of a Logic Gate Circuit Based on Ambipolar Field-Effect Transistors with Thin Films of C₆₀ and Pentacene, Chemical Physics Letters, Vol.413, No.4-6, 379-383, 2005. (出版サイトへのリンク) ● Publication site (DOI): 10.1016/j.cplett.2005.07.096 (文献検索サイトへのリンク) ● Search Scopus @ Elsevier (DOI): 10.1016/j.cplett.2005.07.096 (DOI: 10.1016/j.cplett.2005.07.096)
89.	J. Mbuna, Toshio Takayanagi, M. Oshima and S. Motomizu : Ion-Association Analysis between Inorganic Anions and Symmetrical Tetraalkylammonium Ions in Aqueous-Acetonitrile Media by Capillary Zone Electrophoresis, Bulletin of the Chemical Society of Japan, Vol.78, No.8, 1457-1462, 2005. (出版サイトへのリンク) ● Publication site (DOI): 10.1246/bcsj.78.1457 (文献検索サイトへのリンク) ● CiNii @ 国立情報学研究所 (CRID): 1390282679106352896 ● Search Scopus @ Elsevier (DOI): 10.1246/bcsj.78.1457 (DOI: 10.1246/bcsj.78.1457, CiNii: 1390282679106352896)
90.	T. Nagano, E. Kuwahara, Toshio Takayanagi, Y. Kubozono and A. Fujiwara : Fabrication and Characterization of Field-Effect Transistor Device with C2v Isomer of Pr@C82, Chemical Physics Letters, Vol.409, No.4-6, 187-191, 2005. (要約) Endohedral metallofullerene field-effect transistor (FET) device was fabricated with thin films of C_<2v> isomer of Pr@C_<82>. This device showed n-channel normally-on type FET properties, where high bulk current of Pr@C_<82> was observed at gate voltage of 0 V. The mobility, μ, was estimated to be 1.5 x 10^<-4> cm^2 V^<-1> s^<-1> at 320 K, which is comparable to those of other endohedral metallofullerene FET devices. The normally-on properties have been found to originate from the high bulk current caused by the small energy gap of Pr@C_<82>. (出版サイトへのリンク) ● Publication site (DOI): 10.1016/j.cplett.2005.05.019 (文献検索サイトへのリンク) ● CiNii @ 国立情報学研究所 (CRID): 1050002212698441600 ● Search Scopus @ Elsevier (DOI): 10.1016/j.cplett.2005.05.019 (DOI: 10.1016/j.cplett.2005.05.019, CiNii: 1050002212698441600)
91.	Toshio Takayanagi and P. K. Dasgupta : A Chemiluminescence-Based Continuous Flow Aqueous Ozone Analyzer Using Photoactivated Chromotropic Acid, Talanta, Vol.66, No.4, 823-830, 2005. (要約) Ozone has become the oxidant of choice for water disinfection, especially in large water treatment facilities. This paper describes a fast and sensitive method for the determination of ozone content by reaction with photoactivated chromotropic acid (CA, 4,5-dihydroxynaphthalene-2,7-disulfonic acid), which results in intense chemiluminescence (CL). Freshly ozonated water from a recirculating ozonizer/reservoir is injected into a carrier stream of deionized water in the flow-injection mode. This flow mixes with a stream of photoactivated CA solution in a spiral cell placed directly on top of an inexpensive miniature (8mm diameter active area) photomultiplier tube (PMT). Alkaline CA is photoactivated by passing it through a FEP-Teflon((R)) coil (residence time approximately 50s) wrapped around a 1W UV lamp emitting at 254nm; without photoactivation, the signal is approximately 70-fold lower. The S/N=3 limit of detection for aqueous ozone is 3mugl(-1) and good response slope is obtained up to an ozone concentration of 1.4mgl(-1), the highest that could be made in this study. The response obeyed a quadratic equation with r(2)=0.9984. No interference from permanganate ion is observed. The proposed system was applied to the monitoring of ozonation status of a playa lake water that exhibited significant ozone demand. (出版サイトへのリンク) ● Publication site (DOI): 10.1016/j.talanta.2004.11.036 (文献検索サイトへのリンク) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 18970059 ● Search Scopus @ Elsevier (PMID): 18970059 ● Search Scopus @ Elsevier (DOI): 10.1016/j.talanta.2004.11.036 (DOI: 10.1016/j.talanta.2004.11.036, PubMed: 18970059)
92.	J. Mbuna, Toshio Takayanagi, M. Oshima and S. Motomizu : Capillary Zone Electrophoretic Studies of Ion Association between Inorganic Anions and Tetraalkylammonium Ions in Aqueous-Dioxane Media, Journal of Chromatography. A, Vol.1069, No.2, 261-270, 2005. (要約) Ion association between inorganic anions and symmetrical tetraalkylammonium ions, R4N+ (R = Me, Et, Pr, n-Bu, n-Am, and 2-methyl butyl {isoamyl = iAm}) was investigated using ordinary silica capillary by capillary zone electrophoresis. An improved version of the Williams-Vigh method was used for the first time to measure the mobilities of the inorganic anions. Plots of log Kass against log dielectric constant in various media, revealed a smaller change in Kass compared to dielectric constant. These plots suggest that the Bjerrum's equation is inadequate in accounting for the associations of ions in a CZE setup. (キーワード) Anions / Electrophoresis, Capillary / Mathematics / Quaternary Ammonium Compounds (出版サイトへのリンク) ● Publication site (DOI): 10.1016/j.chroma.2005.02.009 (文献検索サイトへのリンク) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 15830953 ● Search Scopus @ Elsevier (PMID): 15830953 ● Search Scopus @ Elsevier (DOI): 10.1016/j.chroma.2005.02.009 (DOI: 10.1016/j.chroma.2005.02.009, PubMed: 15830953)
93.	後藤晃範, 大島光子, 髙栁俊夫, 本水昌二 : シアニン系新規合成試薬を用いる陰イオン界面活性剤の定量, 分析化学, Vol.53, No.9, 919-923, 2004年. (要約) 水溶液一相系でイオン会合反応を利用する陰イオン界面活性剤直接定量のための陽イオン性染料を新規に合成した.基本骨格はシアニンとし,二つのNに炭素数の異なるn-アルキル鎖を導入した四級塩染料を合成した.アルキル鎖の炭素数4と6のものは新規合成化合物であり,pK_aを求めた.炭素数2と3の市販品と合成した陽イオン試薬を用い,吸光光度法により陰イオン界面活性剤(DBS)との最適反応条件を検討した.3,3'-ジヘキシル-2,2'-チアシアニン(DHT,C6の試薬)を用いて,10^<-6>MオーダーのDBSを定量することができ,検出下限は4×10^<-7>Mであった.また,疎水性相互作用により,非イオン性界面活性剤,陽イオン界面活性剤とも反応することが分かり,DHTとのイオン会合定数を求めた. (キーワード) n-dialkyl-2,2'-thiacyanine dyes / surfactants / ion association / spectrophotometry (出版サイトへのリンク) ● Publication site (DOI): 10.2116/bunsekikagaku.53.919 (文献検索サイトへのリンク) ● CiNii @ 国立情報学研究所 (CRID): 1390001204354099328 ● Search Scopus @ Elsevier (DOI): 10.2116/bunsekikagaku.53.919 (DOI: 10.2116/bunsekikagaku.53.919, CiNii: 1390001204354099328)
94.	J. Mbuna, Toshio Takayanagi, M. Oshima and S. Motomizu : An Investigation of Weak Ion Association Equilibria between Inorganic Anions and Tetraalkylammonium Ions in Ethanol-Aqueous Media Using Capillary Zone Electrophoresis, Bulletin of the Chemical Society of Japan, Vol.77, No.8, 1465-1473, 2004. (出版サイトへのリンク) ● Publication site (DOI): 10.1246/bcsj.77.1465 (文献検索サイトへのリンク) ● CiNii @ 国立情報学研究所 (CRID): 1360565169058392320 ● Search Scopus @ Elsevier (DOI): 10.1246/bcsj.77.1465 (DOI: 10.1246/bcsj.77.1465, CiNii: 1360565169058392320)
95.	髙栁俊夫, R. Driouich, 澤井邦子, Li Q., 大島光子, 本水昌二 : 水溶性シッフ塩基へのマージングゾーン誘導体化/逆相分配高速液体クロマトグラフィーによるn-アルキルアミン類の分離定量, 分析化学, Vol.53, No.7, 723-728, 2004年. (要約) _<n->アルキルアミン類の分離定量法として,陰イオン性アルデヒドを誘導体化試薬として用いる吸光検出-逆相分配高速液体クロマトグラフイーを検討した.誘導体化試薬としては,サリチルアルデヒド-5-スルホン酸イオン(SAS)と4-(4-スルホフェニルアゾ)-1-ヒドロキシ-2-ナフトアルデヒド(SPAHNA)を用いた._<n->アルキルアミンを含む試料溶液と試薬溶液はそれぞれの流路に同時に注入され,マージングゾーン法によりオンラインで混合され,5m,70℃の反応コイル中で水溶性シッフ塩基へと誘導体化された.生成した水溶性シッフ塩基は逆相カラムにより分離され,吸光検出された.オンライン誘導体化とカラム分離/検出を含む分析時間は,SASを用いた場合25分,SPAHNAを用いた場合は18分であった.アルキルアミン類に対する検量線は0∼50μMの範囲で良好な直線性が得られ,検出限界は,SASを用いた場合0.5∼1.0μM,SPAHNAを用いた場合は0.08∼0.20μMであった. (キーワード) n-alkylamines / salicylaldehyde-5-sulfonate / 4-(4-sulfophenylazo)-1-hydroxy-2-naphthaldehyde / merging zone / reversed-phase HPLC (出版サイトへのリンク) ● Publication site (DOI): 10.2116/bunsekikagaku.53.723 (文献検索サイトへのリンク) ● CiNii @ 国立情報学研究所 (CRID): 1390001204356075648 ● Search Scopus @ Elsevier (DOI): 10.2116/bunsekikagaku.53.723 (DOI: 10.2116/bunsekikagaku.53.723, CiNii: 1390001204356075648)
96.	小西明伸, 髙栁俊夫, 大島光子, 本水昌二 : 微量フロー滴定分析法の開発と酸塩基滴定への応用, 分析化学, Vol.53, No.1, 1-6, 2004年. (要約) 容量分析法の簡便化,迅速化,自動化及び省力化を含む高機能化を目的として,送液ポンプの流量比に基づくフロー滴定システムの構築と応用について検討した.フロー滴定分析法は,連続して流れる試料液,滴定剤溶液の正確な流量制御を基本原理としている.2台の送液ポンプを用いてそれらの流量を変化させながら試料液(被滴定液)と滴定剤(滴定液)を送液し,流れ内において混合・反応させ,指示薬の変色を用いて試料液中の分析対象物質濃度を流量比から定量する容量分析法である.各種酸塩基滴定を通して本法の性能評価を行い,従来法との比較を行った.酸塩基指示薬としてフェノールフタレイン,あるいはクレゾールレッドを試料液又は滴定剤へ添加したところ,強酸,弱酸を問わず検討したすべての系において直線性の高い検量線が得られた.また,終点検出の相対標準偏差は0.3%未満であった.更に,滴定剤に2種類の指示薬を用いる多塩基酸・多酸塩基の連続滴定法について検討した.炭酸塩の分析ではブロモクレゾールグリーンとフェノールフタレインを指示薬として用い,炭酸イオン,重炭酸イオンに由来する二つの当量点を一試料測定で検出できた.本法を市販されている食酢の分析に適用したところ,従来法により決定した酢酸濃度と良好な一致を得た.1試料測定当たりの廃液量は50 ml程度から100μl程度まで大幅に低減化することができ,ブロー滴定分析法により全操作の自動化,試料・廃液量の大幅な低減化,滴定時間の短縮等の高機能化を達成した. (キーワード) flow titration analysis / flow ratiometry / acid-base titration (出版サイトへのリンク) ● Publication site (DOI): 10.2116/bunsekikagaku.53.1 (文献検索サイトへのリンク) ● CiNii @ 国立情報学研究所 (CRID): 1390001204355802752 ● Search Scopus @ Elsevier (DOI): 10.2116/bunsekikagaku.53.1 (DOI: 10.2116/bunsekikagaku.53.1, CiNii: 1390001204355802752)
97.	J. Mbuna, Toshio Takayanagi, M. Oshima and S. Motomizu : Evaluation of Weak Ion Association between Tetraalkylammonium Ions and Inorganic Anions in Aqueous Solutions by Capillary Zone Electrophoresis, Journal of Chromatography. A, Vol.1022, No.1-2, 191-200, 2004. (要約) The evaluation of weak ion association between eleven (11) inorganic anions (charge -1 to -3) and five n-tetraalkylammonium ions, R4N+ (R: methyl, Me; ethyl, Et; propyl, Pr; butyl, Bu; pentyl, Am) in aqueous media at 25 degrees C was studied. The analysis of ion association equilibria was carried out under acidic condition (formate buffer, pH 3.5) at low separating potential (-10 kV) using a coated capillary with suppressed electroosmotic flow (micro = 4 x 10(-5) cm2 V(-1) s(-1)). Direct UV detection was done at anode (lambda = 220 nm). The combination of the aforementioned conditions ensured that ion association constants, Kass, between n-tetraalkylammonium ion and the small inorganic anions were reliably determined after a non-linear least squares (NLLS) treatment of the measured anion's mobility. Like their larger counterparts, small anions showed increased interaction with an increase in size of pairing ions. Moreover, for a specific cation, the interaction of small anions increased with an increase in size of the hydrated anions as reflected by the relationship between the Kass and the Stokes' radius. A favourable comparison exists between the results presented in this work and those previously documented from other analytical techniques like conductometry. Qualitatively, the mobility of the anions appeared to obey the Hückel's model more closely than the more elaborate Zwanzig and Hubbard-Onsager models. (キーワード) Anions / Electrophoresis, Capillary / Quaternary Ammonium Compounds / Solutions / Water (出版サイトへのリンク) ● Publication site (DOI): 10.1016/j.chroma.2003.09.051 (文献検索サイトへのリンク) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 14753786 ● Search Scopus @ Elsevier (PMID): 14753786 ● Search Scopus @ Elsevier (DOI): 10.1016/j.chroma.2003.09.051 (DOI: 10.1016/j.chroma.2003.09.051, PubMed: 14753786)
98.	Toshio Takayanagi, X.-L. Su, P. K. Dasgupta, K. Martinelango, G. Li, R. S. Al-Horr and R. W. Shaw : Chemiluminometric Measurement of Atmospheric Ozone with Photoactivated Chromotropic Acid, Analytical Chemistry, Vol.75, No.21, 5916-5925, 2003. (要約) A highly sensitive, robust, fast, affordable measurement system based on interfacial gas-liquid chemiluminescence (CL) on a wetted transparent screen directly on top of a miniature photomultiplier tube provides the basis of an attractive method for ozone (O(3)). Alkaline chromotropic acid (CA, 4,5-dihydroxynaphthalene-2,7-disulfonic acid) chemiluminesces upon exposure to ozone. No light emission is observed from exposure of alkaline CA to NO(2) or H(2)O(2). However, response to ozone is highly dependent on the age and storage condition of the CA solution. As such, quantitative analysis will require frequent calibration, and the method will not be attractive. We have discovered that photoactivation plays the key role in producing (a) compound(s) from chromotropic acid that appear(s) to be the primary agent(s) responsible for the CL reaction with O(3). We thus devised a method wherein a flowing solution of CA (that is stable in neutral/acidic solutions) is rendered alkaline and then exposed for a few seconds on-line to UV radiation. The solution then reacts with ozone on a screen consisting of an "invisible" nylon stocking that provides for low liquid residence time and high light throughput and results in an LOD of 40 pptv, a determination range at least up to 230 ppbv, and 10-90% and 90-10% response times of 130 and 80 ms, respectively. Intra- and interday repeatabilities at the same concentration were 0.32 and 3.8% in relative standard deviation. On the basis of aging, CL, chromatography, and chromatography-mass spectrometry studies, we suggest that the primary CL-active species are likely dimeric semiquinone species derived from CA by a series of radical reactions. (出版サイトへのリンク) ● Publication site (DOI): 10.1021/ac034723n (文献検索サイトへのリンク) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 14588033 ● Search Scopus @ Elsevier (PMID): 14588033 ● Search Scopus @ Elsevier (DOI): 10.1021/ac034723n (DOI: 10.1021/ac034723n, PubMed: 14588033)
99.	R. Driouich, Toshio Takayanagi, M. Oshima and S. Motomizu : Investigation of Salicylaldehyde-5-Sulfonate as a Precolumn Derivatizing Agent for the Determination of n-Alkane Diamines, Lysine, Diaminopimelic Acid, and Isoniazid by Capillary Zone Electrophoresis, Journal of Pharmaceutical and Biomedical Analysis, Vol.30, No.5, 1523-1530, 2003. (要約) Reactions of primary amines with salicylaldehyde-5-sulfonate (SAS) lead to the formation of stable Schiff bases at weakly alkaline pH and at moderate temperature in an ethanol-rich aqueous solution. Some alkane diamines were converted to salicylaldimine with SAS, and the products were resolved and detected by capillary zone electrophoresis (CZE). The reactivity of SAS was applied also to the derivatization of amino acids. Optimal conditions for the analysis of lysine in the presence of diaminopimelic acid, the metabolite of lysine, were investigated. Addition of Na(2)SO(4) into the migrating solution enhanced the stacking effect, and led to increase in the detection limits. Another advantage of the use of SAS is its ability to form stable water-soluble metal chelate as Schiff base ligands. For practical analysis, the copper chelate of the Schiff base of isoniazid, which is known as the most active antibacterial used in the treatment of pulmonary tuberculoses, was investigated, and the detection limit of isoniazid was improved in the magnitude of 11 times compared with the one of free isoniazid. (キーワード) Aldehydes / Alkanes / Diamines / Diaminopimelic Acid / Electrophoresis, Capillary / Isoniazid / Lysine (出版サイトへのリンク) ● Publication site (DOI): 10.1016/S0731-7085(02)00545-9 (文献検索サイトへのリンク) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 12467924 ● Search Scopus @ Elsevier (PMID): 12467924 ● Search Scopus @ Elsevier (DOI): 10.1016/S0731-7085(02)00545-9 (DOI: 10.1016/S0731-7085(02)00545-9, PubMed: 12467924)
100.	香川拓司, 髙栁俊夫, 大島光子, 本水昌二 : 2-(5-ニトロ-2-ピリジルアゾ)-5-(N-プロピル-N-スルホプロピルアミノ)フェノールを用いるキャピラリー電気泳動法によるニッケル，鉄塩中の極微量不純物の定量, 分析化学, Vol.51, No.9, 791-795, 2002年. (要約) 市販金属塩中の極微量金属不純物の定量法として,2-(5-ニトロ-2-ピリジルアゾ)-5-(N-プロピル-N-スルホプロピルアミノ)フェノール (Nitro-PAPS) とのキレートを分離,検出するキャピラリー電気泳動法について検討した.各種金属イオンと定量的に反応する pH7 の条件では,高感度検出が可能であるが,多くの金属錯体の分離は十分でない.そこで,電気浸透流やキレートの電気泳動移動度を変化させる効果のある第四級アンモニウム塩等の添加を検討し,種々な相互作用試薬を用いて分離の改善を図った.その結果,臭化セチルトリメチルアンモニウムの添加で電気浸透流が抑制され,硫酸ナトリウムの添加によるスタッキング効果の活用によりシグナルが鋭敏化され,尿素の添加でニトロ基周りの水和を抑制したところ,金属キレートの分離性能が向上した.本法により 10^-7 M レベルの Fe, Co, Ni, Cu の分離定量が可能になり,市販特級金属塩中の極微量金属の分析に適用したところ,ppm (=10^-6 g/g) レベルの金属不純物を定量することができた. (キーワード) capillary zone electrophoresis / metal ions / 2-(5-nitro-2-pyridylazo)-5-(N-propyl-N-sulfopropylamino) phenol / nickel and iron salt / impurity analysis (出版サイトへのリンク) ● Publication site (DOI): 10.2116/bunsekikagaku.51.791 (文献検索サイトへのリンク) ● CiNii @ 国立情報学研究所 (CRID): 1390001204052243712 ● Summary page in Scopus @ Elsevier: 2-s2.0-0036386746 (DOI: 10.2116/bunsekikagaku.51.791, CiNii: 1390001204052243712, Elsevier: Scopus)
101.	野村一央, 大島光子, 髙栁俊夫, 本水昌二 : 1,8-ジアミノナフタレン-3,6-ジスルホン酸骨格を持つ新規水溶性蛍光試薬の合成と銅イオンの高感度定量への応用, 分析化学, Vol.51, No.9, 785-789, 2002年. (要約) 水溶性蛍光試薬として 1,8-ジヒドロキシナフタレン-3,6-ジスルホン酸(クロモトロープ酸)に類似した1,8-ジアミノナフタレン-3,6-ジスルホン酸骨格を持つ1,8-ジ-(トルエン-4-スルホニルアミノ)-ナフタレン-3,6-ジスルホン酸 (BTND) 及び1,8-ジ-(トリフルオロメタンスルホニルアミノ)-ナフタレン-3,6-ジスルホン酸 (BTFND) を合成し,金属イオンとの反応性を検討した.BTFND は検討した8種類の金属イオンと反応し消蛍光を示した.また BTND は銅(II) イオンと選択的に反応することが分かった.BTND は水溶液中 pH7 で銅(II) イオンと定量的に反応し,消蛍光を示したので,検量線を作成したところ,銅濃度0∼10^-6Mの範囲で直線関係を示した (λ_ex=360 nm, λ_em=405 nm).本法の銅(II) イオンの検出下限は 2.0×10^-7M であった.BTND は水溶液中で反応し,定量操作が簡便で,銅(II) イオンに対する高感度・高選択的な蛍光試薬であることが分かった. (キーワード) determination of copper ion / 1,8-di-(toluene-4-sulfonylamino)-naphthalene-3,6-disulfonic acid / 1,8-di-(trifluoromethane-4-sulfonylamino)-naphthalene-3,6-disulfonic acid / fluorescence detection (出版サイトへのリンク) ● Publication site (DOI): 10.2116/bunsekikagaku.51.785 (文献検索サイトへのリンク) ● CiNii @ 国立情報学研究所 (CRID): 1390282679028957696 ● Summary page in Scopus @ Elsevier: 2-s2.0-4143056071 (DOI: 10.2116/bunsekikagaku.51.785, CiNii: 1390282679028957696, Elsevier: Scopus)
102.	Toshio Takayanagi and S. Motomizu : Equilibrium Analysis of Reactions of Metal-Pyridylazoresorcinolato Chelates with Quaternary Ammonium Ion, Nonionic Surfactant and Polyethylene Glycol in Aqueous Solution by Capillary Zone Electrophoresis, Analytical Sciences, Vol.18, No.9, 1021-1025, 2002. (要約) The resolutions of metal-4-(2-pyridylazo)resorcinol chelates by capillary zone electrophoresis (CZE) were investigated in the presence of some interacting reagents; also, equilibrium reactions between the chelates and the interacting reagents were analyzed in an aqueous solution. Among nine metal chelates formed in aqueous solution, the chelates of VV, FeII, CoIII, NiII, and CuII were resolved and detected by CZE, while other chelates were decomposed during electrophoretic migration. The electrophoretic mobility of the chelates of FeII, NiII, and CuII increased with increasing pH of the migrating solution; also, the acid-dissociation constants of these three chelates were determined by analyzing the mobility change. The ion-association constants of the five anionic chelates and pyridylazoresorcinolate ion with quaternary ammonium ions were also determined by analyzing the mobility change. The binding behavior of the ligand and its chelates with nonionic surfactant micelle, as well as with polyethylene glycol, were investigated, and their binding constants were determined through the mobility change. When Brij 35 was used as a nonionic surfactant interacting with the anionic chelates, the FeII chelate decomposed at Brij 35 concentrations over 6.67 mM. The equilibrium constants and the reactivity were compared with each other. (出版サイトへのリンク) ● Publication site (DOI): 10.2116/analsci.18.1021 (文献検索サイトへのリンク) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 12243397 ● Search Scopus @ Elsevier (PMID): 12243397 ● Search Scopus @ Elsevier (DOI): 10.2116/analsci.18.1021 (DOI: 10.2116/analsci.18.1021, PubMed: 12243397)
103.	Y. Wei, M. Oshima, Toshio Takayanagi and S. Motomizu : Continuous In-Situ Analysis of Total Carbonate in Water by a Reversed-Flow Injection Method, Journal of Flow Injection Analysis, Vol.18, No.2, 156-161, 2001. (キーワード) spectrophotometry / reversed FIA / gas diffusion unit / total carbonate / river water (文献検索サイトへのリンク) ● CiNii @ 国立情報学研究所 (CRID): 1520009408742153216 (CiNii: 1520009408742153216)
104.	K. Oshita, Toshio Takayanagi, M. Oshima and S. Motomizu : Complex Formation Analysis of Water-Soluble Calixarenes by Capillary Zone Electrophoresis, Journal of Chromatography. A, Vol.934, No.1-2, 113-122, 2001. (要約) The equilibria of complex formation reactions between various kinds of cations and anionic calixarenes in an aqueous solution were analyzed by capillary zone electrophoresis on the basis of the change in electrophoretic mobility of the calixarenes. The apparent electrophoretic mobility of the calixarenes decreased with increasing concentrations of alkali metal ions and quaternary ammonium ions. Equilibrium constants were determined by a non-liner least-squares analysis using the changes in apparent electrophoretic mobility. The complex formation constants obtained with alkali metal ions were in the order of 10(2.3) - 10(3.0), and those with quaternary ammonium ions were 10(2.9) - 10(4.2), providing less selectivity among them. The selectivity of the calixarene toward alkali metal and quaternary ammonium ions in aqueous solution involves flexible structure, and compensative interactions of electrostatic and hydrophobic interactions. From the results obtained in this work, the electrophoretic method has proved to be useful for analyzing the reactivity of anionic calixarene in aqueous solution. (キーワード) Alkalies / Calixarenes / Electrophoresis, Capillary / Macromolecular Substances / Metals / Sensitivity and Specificity / Solubility / Water (出版サイトへのリンク) ● Publication site (DOI): 10.1016/S0021-9673(01)01298-5 (文献検索サイトへのリンク) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 11762758 ● Search Scopus @ Elsevier (PMID): 11762758 ● Search Scopus @ Elsevier (DOI): 10.1016/S0021-9673(01)01298-5 (DOI: 10.1016/S0021-9673(01)01298-5, PubMed: 11762758)
105.	R. Driouich, Toshio Takayanagi, M. Oshima and S. Motomizu : Separation and Determination of n-Alkylamines and Histamine by Capillary Zone Electrophoresis Using Salicylaldehyde-5-Sulfonate as a Derivatizing Reagent, Journal of Chromatography. A, Vol.934, No.1-2, 95-103, 2001. (要約) Sodium salicylaldehyde-5-sulfonate (SAS) was investigated as a derivatizing reagent for the separation and determination of primary amines by capillary zone electrophoresis (CZE). The amines were derivatized with SAS to the corresponding Schiff bases before their determination. Optimal conditions for the formation reactions of the Schiff bases and the CZE analysis were investigated in details. The Schiff bases were formed almost completely within 9 min in 40%(v/v) ethanol solution at 40 degrrees C. A migrating solution containing 40%(v/v) ethanol and 20 mM phosphate buffer (pH 7.8) was found to be preferable for the stability of the Schiff bases. Eight kinds of n-alkylamines were derivatized with SAS under the optimal conditions and the derivatives were successfully separated by a CZE analysis. The proposed method allows simultaneous, sensitive and sufficiently precise determination of the n-alkylamines with the alkyl chain length from 3 to 12 of methylene groups. The derivatization process with SAS was successfully applied to the detection of histamine at a very low level. The detection limit was 2.5-10(-6) M, and it was improved in the order of 8 times compared with the CZE analysis without derivatization. (キーワード) Aldehydes / Amines / Electrophoresis, Capillary / Histamine / Indicators and Reagents / Schiff Bases / Temperature (出版サイトへのリンク) ● Publication site (DOI): 10.1016/S0021-9673(01)01280-8 (文献検索サイトへのリンク) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 11762768 ● Summary page in Scopus @ Elsevier: 2-s2.0-0035900214 (DOI: 10.1016/S0021-9673(01)01280-8, PubMed: 11762768, Elsevier: Scopus)
106.	Toshio Takayanagi and S. Motomizu : Binding of Phenol Derivatives to Nonionic Surfactant Micelles as Studied by Capillary Zone Electrophoresis, Bulletin of the Chemical Society of Japan, Vol.74, No.11, 2083-2089, 2001. (出版サイトへのリンク) ● Publication site (DOI): 10.1246/bcsj.74.2083 (文献検索サイトへのリンク) ● Summary page in Scopus @ Elsevier: 2-s2.0-0035788448 (DOI: 10.1246/bcsj.74.2083, Elsevier: Scopus)
107.	M. Oshima, Y. Wei, M. Yamamoto, H. Tanaka, Toshio Takayanagi and S. Motomizu : Highly Sensitive Determination Method for Total Carbonate in Water Samples by Flow Injection Analysis Coupled with Gas-Diffusion Separation, Analytical Sciences, Vol.17, No.11, 1285-1290, 2001. (要約) A spectrophotometric method for the determination of total carbonate in water samples was developed. The method is based on the color change of an acid-base indicator in relation to the concentration of permeable gas substances through a membrane. By using a new portable FIA system equipped with a gas-diffusion unit, a highly sensitive and on-site determination of total carbonate in aqueous solutions was investigated. A new color-change system with 4-(2',4'-dinitrophenylazo)-1-naphthol-5-sulfonic acid (DNN5S) was developed. Absorbance changes of the reagent solution were measured at 450 nm with a light-emitting diode (LED) as a light source. A new type of gas-diffusion unit was used, and was constructed with double tubing: the inner tubing was a micro porous PTFE (polytetrafluoroethylene) tubing (1.0 mm inner diameter and 1.8 mm outer diameter, pore size 2 microns, porosity 50%); the outer tubing was made of glass with 2.0 mm inner diameter. The optimized system conditions were as follows: the sample size was 200 microliters, the temperature of the air bath for the gas-diffusion unit was 25 degrees C, and the length of the gas-diffusion unit was 15 cm; each flow rate was 0.3 ml min-1. For measuring carbonate at low concentrations, a method for preparing water with less carbonate was proposed: the carbonate content of the water was decreased down to 5 x 10(-7) M. The calibration graph was rectilinear from 1 x 10(-6) M to 10(-3) M, and the detection limit (corresponding to a signal-to-noise ratio of 3) was 1 x 10(-6) M of carbonate. The relative standard deviation (RSD) of ten measurements of 2.3 x 10(-5) M Na2CO3 solution was 1.9%. The total carbonate in various kinds of water (such as river, sea, rain, distilled and ultra purified) was determined. (キーワード) Carbonates / Diffusion / Flow Injection Analysis / Fresh Water / Gases / Seawater / Water (出版サイトへのリンク) ● Publication site (DOI): 10.2116/analsci.17.1285 (文献検索サイトへのリンク) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 11759510 ● Summary page in Scopus @ Elsevier: 2-s2.0-0035216859 (DOI: 10.2116/analsci.17.1285, PubMed: 11759510, Elsevier: Scopus)
108.	Toshio Takayanagi, I. Ikeda and S. Motomizu : Analysis of Complex Formation between Crown Ethers and Potassium Ion by Determining Retention Factors in Reversed-Phase High-Performance Liquid Chromatography, Journal of Chromatography. A, Vol.932, No.1-2, 165-170, 2001. (要約) Retention factors in reversed-phase high-performance liquid chromatography (RP-HPLC) were utilized for the analysis of complex formation reaction of four crown ethers with potassium ion in water-methanol media. The crown ethers were injected as analytes, potassium ion was present in the eluent, and three types of reversed-phase columns were used. The retention factor of the crown ethers decreased with increasing concentrations of potassium ion in the eluent, which is attributed to the change in the species of the crown ether from a neutral ligand to a positively charged complex. The complex formation constants were determined by analyzing the changes in the retention factor with a non-linear least-squares method. (キーワード) Chromatography, High Pressure Liquid / Ethers, Cyclic / Methanol / Potassium (出版サイトへのリンク) ● Publication site (DOI): 10.1016/S0021-9673(01)01248-1 (文献検索サイトへのリンク) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 11695863 ● Summary page in Scopus @ Elsevier: 2-s2.0-0035850739 (DOI: 10.1016/S0021-9673(01)01248-1, PubMed: 11695863, Elsevier: Scopus)
109.	L. Ma, M. Oshima, Toshio Takayanagi and S. Motomizu : Determination of Nitrogen Dioxide in the Atmosphere by Microflow-Injection Absorptiometry with a Portable-Type Flow System after Batchwise Absorption Collection, Journal of Flow Injection Analysis, Vol.17, No.2, 188-193, 2000.
110.	R. Driouich, Toshio Takayanagi, M. Oshima and S. Motomizu : Separation and Determination of Haloperidol, Parabens and Some of Their Degradation Products by Micellar Electrokinetic Chromatography, Journal of Chromatography. A, Vol.903, No.1-2, 271-278, 2000. (要約) A micellar solution containing phosphate buffer, anionic surfactant, and water-miscible organic solvent was employed as a migration solution for the separation and the quantification of eleven analytes by micellar electrokinetic chromatography (MEKC): the analytes examined were haloperidol, methylparaben, ethylparaben, n-propylparaben, iso-propylparaben, n-butylparaben, iso-butylparaben, sec-butylparaben, 4-(4-chlorophenyl)-4-hydroxypiperidine, 4-fluorobenzoic acid and 4-hydroxybenzoic acid. In order to provide good separation between micelle and haloperidol, which showed strongest interaction with the micelle among the analytes, surfactant concentrations and organic modifier percentages were studied with phosphate buffer at pH 7.0. All the analytes were successfully resolved when 10 mM sodium dodecylsulfate and 15% ethanol were contained in the migration solution; the time window was very wide in the range from 14.8 to 65.5 min. Optimized applied voltage at 30 kV and capillary temperature at 45 degrees C enable analyze all compounds in less than 17 min with the best resolution, the shorter migration time window, the highest precision and lowest detection limit. (キーワード) Benzoates / Calibration / Chromatography, Micellar Electrokinetic Capillary / Haloperidol / Parabens / Piperidines (出版サイトへのリンク) ● Publication site (DOI): 10.1016/S0021-9673(00)00869-4 (文献検索サイトへのリンク) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 11153952 ● Summary page in Scopus @ Elsevier: 2-s2.0-0034672407 (DOI: 10.1016/S0021-9673(00)00869-4, PubMed: 11153952, Elsevier: Scopus)
111.	Ludovick C. Manege, Toshio Takayanagi, Mitsuko Oshima and Shoji Motomizu : Ion Association Reactions in Aqueous Solutions between Non-UV-Absorbing Crown Ether-Alkali Metal Complexes with Picrate Ion by Capillary Zone Electrophoresis, Analyst, Vol.125, No.11, 1928-1932, 2000. (出版サイトへのリンク) ● Publication site (DOI): 10.1039/b005211f (文献検索サイトへのリンク) ● Summary page in Scopus @ Elsevier: 2-s2.0-0033709428 (DOI: 10.1039/b005211f, Elsevier: Scopus)
112.	Toshio Takayanagi, K. Fushimi and S. Motomizu : Analysis of Reactions of Aromatic Anions with Quaternary Ammonium Ions in Ion Association-Nonionic Micellar Electrokinetic Chromatography, Bulletin of the Chemical Society of Japan, Vol.73, No.11, 2505-2511, 2000. (出版サイトへのリンク) ● Publication site (DOI): 10.1246/bcsj.73.2505 (文献検索サイトへのリンク) ● Summary page in Scopus @ Elsevier: 2-s2.0-0033695206 (DOI: 10.1246/bcsj.73.2505, Elsevier: Scopus)
113.	K.-H. Lee, M. Oshima, Toshio Takayanagi and S. Motomizu : Simultaneous Determination of Trace Elements in River-Water Samples by ICP-MS in Combination with a Discrete Microsampling Technique after Enrichment with a Chitosan-Based Chelating Resin, Analytical Sciences, Vol.16, No.7, 731-738, 2000. (出版サイトへのリンク) ● Publication site (DOI): 10.2116/analsci.16.731 (文献検索サイトへのリンク) ● Summary page in Scopus @ Elsevier: 2-s2.0-0033870824 (DOI: 10.2116/analsci.16.731, Elsevier: Scopus)
114.	L. C. Manege, Toshio Takayanagi, M. Oshima and S. Motomizu : Analysis of Ion Association Reactions in Aqueous Solutions between Alkali Metal-Crown Ether Complexes and Pairing Anions by Capillary Zone Electrophoresis, The Analyst, Vol.125, No.4, 699-703, 2000.
115.	Toshio Takayanagi, N. Ban, E. Wada, M. Oshima and S. Motomizu : Analysis of Ion Association Reactions between Monovalent Polycyclic Aromatic Cations and Anions in Aqueous Solution as Studied by Capillary Zone Electrophoresis, Bulletin of the Chemical Society of Japan, Vol.73, No.3, 669-673, 2000.
116.	K.-H Lee, M. Oshima, Toshio Takayanagi and S. Motomizu : Simultaneous Determination of Lanthanoids and Yttrium in Rock Reference Samples by Inductively Coupled Plasma-Mass Spectrometry Coupled with Cation Exchange Pretreatment, Bulletin of the Chemical Society of Japan, Vol.73, No.3, 615-622, 2000. (出版サイトへのリンク) ● Publication site (DOI): 10.1246/bcsj.73.615 (文献検索サイトへのリンク) ● Search Scopus @ Elsevier (DOI): 10.1246/bcsj.73.615 (DOI: 10.1246/bcsj.73.615)
117.	K.-H. Lee, M. Oshima, Toshio Takayanagi and S. Motomizu : Determination of Trace Elements in Water Samples by Inductively Coupled Plasma-Mass Spectrometry Connected with Air Flow- and Water Flow-Injection Techniques, Journal of Flow Injection Analysis, Vol.16, No.2, 255-264, 1999.
118.	Toshio Takayanagi and Shoji Motomizu : Equilibrium Analysis of Reactions between Aromatic Anions and Nonionic Surfactant Micelles by Capillary Zone Electrophoresis, Journal of Chromatography. A, Vol.853, No.1-2, 55-61, 1999. (要約) Separability of some positional isomers of aromatic anions by capillary zone electrophoresis was improved by adding nonionic surfactants to a migrating solution. Eleven kinds of aromatic anions, including positional isomers, were used as analytes, and Brij-35, Brij-58 and Brij-78 were investigated as nonionic surfactants to form micelles, where hydrophobicities are different from each other. Increasing the concentration of the surfactants developed the separability of the anionic isomers. The interaction between the anions and the nonionic surfactant micelles is also investigated through the change in the electrophoretic mobility, and the binding constants are determined. Apparent electrophoretic mobility of the anions decreased with increasing concentrations of the nonionic surfactants. The decrease in the mobility, as well as the binding constant, was larger in the monovalent anions than in the divalent anions, which indicates that the interaction or reactivity of the monovalent analytes is higher than that of the divalent analytes. The reactivity of each anion was almost identical even when the kinds of the surfactants were changed, suggesting that the hydrophobicity of the polyoxyethylene group in the surfactant would have the main role for binding the analytes. The reactivity tendency among the positional isomers was almost similar to that in ion association-capillary zone electrophoresis using tertabutylammonium ion as a pairing ion. The results obtained in this work suggest that the anions are bound to the micelles by the hydrophobic interaction between analyte anions and the polyoxyethylene moiety of the surfactant micelles. Changes in the fluorescence intensity of the anions were also investigated; the results can explain well the mobility changes of the analytes. (キーワード) Anions / Carboxylic Acids / Electrophoresis, Capillary / Micelles / Models, Chemical / Naphthalenesulfonates / Spectrometry, Fluorescence / Stereoisomerism / Surface-Active Agents (出版サイトへのリンク) ● Publication site (DOI): 10.1016/S0021-9673(99)00438-0 (文献検索サイトへのリンク) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 10486712 ● Summary page in Scopus @ Elsevier: 2-s2.0-0032810432 (DOI: 10.1016/S0021-9673(99)00438-0, PubMed: 10486712, Elsevier: Scopus)
119.	S. Motomizu and Toshio Takayanagi : Electrophoretic Mobility Study on Ion-Ion Interactions in an Aqueous Solution, Journal of Chromatography. A, Vol.853, No.1-2, 63-69, 1999. (出版サイトへのリンク) ● Publication site (DOI): 10.1016/S0021-9673(99)00453-7 (文献検索サイトへのリンク) ● Summary page in Scopus @ Elsevier: 2-s2.0-0032767612 (DOI: 10.1016/S0021-9673(99)00453-7, Elsevier: Scopus)
120.	Toshio Takayanagi, E. Wada, M. Oshima and S. Motomizu : Ion Association of Primary Ammonium Ions with Aromatic Anions by Capillary Zone Electrophoresis, Bulletin of the Chemical Society of Japan, Vol.72, No.8, 1785-1791, 1999.
121.	馬蘭, 坪井智則, 服部隆康, 大島光子, 髙栁俊夫, 本水昌二 : 環境中の窒素，リン，硫黄化合物のオンサイト化学分析:マイクロフローインジェクション法による高感度定量, Journal of Flow Injection Analysis, Vol.16, No.1, 79-87, 1999年.
122.	L. C. Manege, Toshio Takayanagi, M. Oshima, T. Iwachido and S. Motomizu : Analysis of Reactions between Crown Ethers and Alkali or Alkaline Earth Metal Cations in Aqueous Solutions by Capillary Zone Electrophoresis, Bulletin of the Chemical Society of Japan, Vol.72, No.6, 1301-1306, 1999. (出版サイトへのリンク) ● Publication site (DOI): 10.1246/bcsj.72.1301 (文献検索サイトへのリンク) ● Search Scopus @ Elsevier (DOI): 10.1246/bcsj.72.1301 (DOI: 10.1246/bcsj.72.1301)
123.	Toshio Takayanagi, N. Ban, H. Takao, N. Nakamura, M. Oshima and S. Motomizu : Ion-Association Study of Methyl Orange Analogues with Quaternary Ammonium Ions in Aqueous Solution by Capillary Zone Electrophoresis, Analytical Sciences, Vol.15, No.6, 593-596, 1999. (出版サイトへのリンク) ● Publication site (DOI): 10.2116/analsci.15.593 (文献検索サイトへのリンク) ● Summary page in Scopus @ Elsevier: 2-s2.0-0033379565 (DOI: 10.2116/analsci.15.593, Elsevier: Scopus)
124.	A. R. Timerbaev, Toshio Takayanagi and S. Motomizu : Separation of Inorganic Anions for Analysis of Sea-Water by Capillary Zone Electrophoresis, Analytical Communications, Vol.36, No.2, 139-141, 1999.
125.	Toshio Takayanagi, E. Wada and S. Motomizu : Direct Photometric Determination of Tungstate Ion in the Etching Solutions by Capillary Zone Electrophoresis, Analytical Sciences, Vol.14, No.12, 1181-1183, 1998.
126.	髙栁俊夫, 宮智子, 本水昌二 : 非イオン界面活性剤ミセル存在下におけるトリフェニルメタン系陽イオン染料からトリフェニルメタノール生成の速度論的研究, 分析化学, Vol.47, No.12, 953-958, 1998年. (出版サイトへのリンク) ● Publication site (DOI): 10.2116/bunsekikagaku.47.953 (文献検索サイトへのリンク) ● Search Scopus @ Elsevier (DOI): 10.2116/bunsekikagaku.47.953 (DOI: 10.2116/bunsekikagaku.47.953)
127.	Toshio Takayanagi, T. Iwachido and S. Motomizu : Analysis of Ion Association Reaction between Crown Ether Complexes of Alkali Metal Ions and Hydrophobic Anions by Capillary Zone Electrophoresis, Bulletin of the Chemical Society of Japan, Vol.71, No.6, 1373-1379, 1998.
128.	Toshio Takayanagi, Y. Ohba, H. Haruki, E. Wada and S. Motomizu : Equilibrium Study on the Ion Association of Monovalent and Divalent Naphtholsulfonates with Tetrabutylammonium Ion in an Aqueous Solution by Capillary Zone Electrophoresis, Analytical Sciences, Vol.14, No.4, 311-315, 1998.
129.	E. Wada, Toshio Takayanagi and S. Motomizu : Capillary Zone Electrophoretic Separation of Aromatic Anions Utilizing Enhanced Ion Associability with Viologen Cations, The Analyst, Vol.123, No.3, 493-495, 1998.
130.	Toshio Takayanagi, E. Wada and S. Motomizu : Separation of Divalent Aromatic Anions by Capillary Zone Electrophoresis Using Multipoint Ion Association with Divalent Quaternary Ammonium Ions, The Analyst, Vol.122, No.11, 1387-1391, 1997.
131.	Toshio Takayanagi and S. Motomizu : Thermodynamic Study of Ion-Association Reactions between Aromatic Anions and Tetrabutylammonium Ion in an Aqueous Solution, Analytical Sciences, Vol.13, No.10, 783-789, 1997.
132.	髙栁俊夫, 和田栄子, 本水昌二 : キャピラリー電気泳動法による第四級アンモニウムイオンと一価有機酸イオンとのイオン会合反応の解析, 分析化学, Vol.46, No.6, 467-475, 1997年.
133.	Toshio Takayanagi, H. Tanaka and S. Motomizu : Ion Association Reaction between Divalent Anionic Azo Dyes and Hydrophobic Quaternary Ammonium Ions in Aqueous Solution as Studied by Capillary Zone Electrophoresis, Analytical Sciences, Vol.13, No.2, 11-18, 1997.
134.	Toshio Takayanagi, E. Wada and S. Motomizu : Electrophoretic Mobility Study of Ion Association between Aromatic Anions and Quaternary Ammonium Ions in Aqueous Solution, The Analyst, Vol.122, No.1, 57-62, 1997.
135.	Toshio Takayanagi, E. Wada and S. Motomizu : Separation and Direct Photometric Determination of Inorganic Anions by Capillary Zone Electrophoresis Using Suppressed Electroosmosis, Analytical Sciences, Vol.12, No.8, 575-579, 1996.
136.	髙栁俊夫, 廣井康子, 本水昌二 : 硫酸イオンの試料イオンに対するスタッキング効果を利用する無機陰イオンのキャピラリー電気泳動/直接吸光分析, 分析化学, Vol.45, No.7, 697-699, 1996年.
137.	Toshio Takayanagi and T. Yotsuyanagi : Ion-Associate Solvent Extraction and Separation of Lanthanides(III) with 2,3-Naphthalenediol and Benzyldimethyltetradecylammonium Chloride, Bulletin of the Chemical Society of Japan, Vol.67, No.7, 1835-1839, 1994. (出版サイトへのリンク) ● Publication site (DOI): 10.1246/bcsj.67.1835 (文献検索サイトへのリンク) ● Search Scopus @ Elsevier (DOI): 10.1246/bcsj.67.1835 (DOI: 10.1246/bcsj.67.1835)

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2.	髙栁俊夫 : 名は体を表すFIA, FIA研究懇談会会誌, Vol.30, No.2, 95, 2013年.
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4.	Toshio Takayanagi, Y. Takimoto, A. Ikuta and S. Motomizu : Analysis of Binding Reactions of Ionic Substances to Nonionic Surfactant Micelles, Solvent Extraction: Fundamental to Industrial Applications, No.2, 793-798, 2008.
5.	R. Driouich, Toshio Takayanagi and S. Motomizu : Separation and Determination of Alkane Diamines by Capillary Electrophoresis Using Salicylaldehyde Sulfonate as a Derivatizing Reagent, Analytical Sciences, Vol.17, No.Supplement, a343-a346, 2001.
6.	Toshio Takayanagi, T. Ninomiya and S. Motomizu : Separation of Aromatic Substances by Micellar Electrokinetic Chromatography Using Surfactants Possessing Polyoxyethylene Moiety, Analytical Sciences, Vol.17, No.Supplement, a133-a136, 2001.
7.	S. Motomizu, Toshio Takayanagi and E. Wada : A Mechanistic Study on Ion Association Extraction with Quaternary Ammonium Ions, Solvent Extraction for the 21st Century, No.1, 591-596, 2001.
8.	Toshio Takayanagi, L. C. Manege and S. Motomizu : Equilibrium Analysis of Crown Ether Complexes by Capillary Zone Electrophoresis, The Journal of Microcolumn Separations : JMS, Vol.12, No.2, 113-119, 2000. (出版サイトへのリンク) ● Publication site (DOI): 10.1002/(SICI)1520-667X(2000)12:2<113::AID-MCS8>3.0.CO;2-Z (文献検索サイトへのリンク) ● Summary page in Scopus @ Elsevier: 2-s2.0-0000825349 (DOI: 10.1002/(SICI)1520-667X(2000)12:2<113::AID-MCS8>3.0.CO;2-Z, Elsevier: Scopus)
9.	Toshio Takayanagi, K. Fushimi and S. Motomizu : Separation of Various Positional Isomers of Aromatic Anions by Nonionic Micellar Electrokinetic Chromatography Coupled with Ion Association Distribution, The Journal of Microcolumn Separations : JMS, Vol.12, No.2, 107-112, 2000. (出版サイトへのリンク) ● Publication site (DOI): 10.1002/(SICI)1520-667X(2000)12:2<107::AID-MCS7>3.0.CO;2-R (文献検索サイトへのリンク) ● Summary page in Scopus @ Elsevier: 2-s2.0-0001026311 (DOI: 10.1002/(SICI)1520-667X(2000)12:2<107::AID-MCS7>3.0.CO;2-R, Elsevier: Scopus)
10.	S. Motomizu, Toshio Takayanagi and E. Wada : Ion Association Study in Aqueous Solution Using Capillary Electrophoresis, Analytical Sciences, Vol.13, No.Supplement, 239-242, 1997. (出版サイトへのリンク) ● Publication site (DOI): 10.2116/analsci.13.Supplement_239 (文献検索サイトへのリンク) ● Search Scopus @ Elsevier (DOI): 10.2116/analsci.13.Supplement_239 (DOI: 10.2116/analsci.13.Supplement_239)
11.	Toshio Takayanagi and T. Yotsuyanagi : Extraction Removal of Transition Metal Ions from Lanthanides with 5,7-dimethyl-8-quinolinol, Proceedings of Symposium on Solvent Extraction, Vol.1991, 33-38, 1991.

学術レター:

1.	Mine Masanori, Hitoshi Mizuguchi and Toshio Takayanagi : Inhibition Assay of Theophylline by Capillary Electrophoresis/Dynamic Frontal Analysis on the Hydrolysis of p-Nitrophenyl Phosphate with Alkaline Phosphatase, Chemistry Letters, Vol.49, No.6, 681-684, 2020. (キーワード) Capillary electrophoresis / Alkaline phosphatase / Inhibition assay (徳島大学機関リポジトリ) ● Metadata: 114845 (出版サイトへのリンク) ● Publication site (DOI): 10.1246/cl.200130 (文献検索サイトへのリンク) ● Search Scopus @ Elsevier (DOI): 10.1246/cl.200130 (徳島大学機関リポジトリ: 114845, DOI: 10.1246/cl.200130)
2.	Toshio Takayanagi and S. Motomizu : Equilibrium Analysis of Acid Dissociation Reactions of Phenolphthalein by Using Mobility Change in Capillary Zone Electrophoresis, Chemistry Letters, Vol.2001, No.1, 14-15, 2001. (出版サイトへのリンク) ● Publication site (DOI): 10.1246/cl.2001.14 (文献検索サイトへのリンク) ● Summary page in Scopus @ Elsevier: 2-s2.0-0035530828 (DOI: 10.1246/cl.2001.14, Elsevier: Scopus)
3.	Toshio Takayanagi and S. Motomizu : Novel Approach to the Reaction Analysis of Non-UV-Absorbing Crown Ether with Alkali Metal Ions in Aqueous Solution by Capillary Zone Electrophoresis Using Indirect Photometric Detection, Chemistry Letters, Vol.1999, No.6, 523-524, 1999.
4.	Toshio Takayanagi and S. Motomizu : Analysis of Ion Association Property of Aromatic Divalent Anions with Quaternary Ammonium Ions in Aqueous Solution through Mobility Change of Capillary Electrophoresis, Chemistry Letters, Vol.1995, No.6, 593-594, 1995.
5.	Toshio Takayanagi, T. Kudoh and T. Yotsuyanagi : 5,7-Dimethyl-8-Quinolinol as a Specific Non-Extracting Reagent for Lanthanide Ions at Usual pH Region, Chemistry Letters, Vol.1994, No.4, 687-690, 1994. (出版サイトへのリンク) ● Publication site (DOI): 10.1246/cl.1994.687 (文献検索サイトへのリンク) ● Search Scopus @ Elsevier (DOI): 10.1246/cl.1994.687 (DOI: 10.1246/cl.1994.687)

総説・解説:

1.	髙栁俊夫 : 分離分析によるナノ粒子のキャラクタリゼーション, --- 溶液中に分散したナノ粒子の直接測定 ---, 化学, Vol.79, No.11, 76-77, 2024年11月.
2.	Toshio Takayanagi : Polymer Nanofibers, Analytical Sciences, Vol.38, No.10, 1245-1246, Oct. 2022. (キーワード) Chromatography, High Pressure Liquid / Nanofibers / Polymers / Solid Phase Extraction (徳島大学機関リポジトリ) ● Metadata: 117535 (出版サイトへのリンク) ● Publication site (DOI): 10.1007/s44211-022-00144-0 (文献検索サイトへのリンク) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 36161423 ● Search Scopus @ Elsevier (PMID): 36161423 ● Search Scopus @ Elsevier (DOI): 10.1007/s44211-022-00144-0 (徳島大学機関リポジトリ: 117535, DOI: 10.1007/s44211-022-00144-0, PubMed: 36161423)
3.	髙栁俊夫 : 分離分析を活用する炭素ナノクラスターのキャラクタリゼーション, ぶんせき, No.5, 191-192, 2022年5月. (徳島大学機関リポジトリ) ● Metadata: 117037 (文献検索サイトへのリンク) ● CiNii @ 国立情報学研究所 (CRID): 1050855112783490048 (徳島大学機関リポジトリ: 117037, CiNii: 1050855112783490048)
4.	Toshio Takayanagi : Development of Novel Analysis and Characterization Methods Utilizing Reaction Dynamics in a Separation Capillary, Chromatography, Vol.43, No.1, 1-14, Feb. 2022. (徳島大学機関リポジトリ) ● Metadata: 116677 (出版サイトへのリンク) ● Publication site (DOI): 10.15583/jpchrom.2021.022 (文献検索サイトへのリンク) ● Search Scopus @ Elsevier (DOI): 10.15583/jpchrom.2021.022 (徳島大学機関リポジトリ: 116677, DOI: 10.15583/jpchrom.2021.022)
5.	Toshio Takayanagi : Monitoring of Ambient Ozone: Instrumentations and Applications, Journal of Flow Injection Analysis, Vol.34, No.2, 67-70, Dec. 2017. (徳島大学機関リポジトリ) ● Metadata: 114225 (徳島大学機関リポジトリ: 114225)
6.	髙栁俊夫, 本水昌二 : シーケンシャルインジェクション分析, ぶんせき, Vol.2007, No.1, 31-37, 2007年1月. (文献検索サイトへのリンク) ● CiNii @ 国立情報学研究所 (CRID): 1520009407466679424 (CiNii: 1520009407466679424)
7.	髙栁俊夫 : フッ素化界面活性剤の環境拡散と生体蓄積, ぶんせき, Vol.2006, No.4, 170-171, 2006年4月.
8.	Toshio Takayanagi : Analysis of Chemical Equilibria in Aqueous Solution Related with Separation Development Using Capillary Zone Electrophoresis, Chromatography, Vol.26, No.1, 11-21, Mar. 2005. (キーワード) chemical equilibria / intermolecular interaction / capillary zone electrophoresis / electrophoretic mobility / ion association reaction / binding reaction (文献検索サイトへのリンク) ● CiNii @ 国立情報学研究所 (CRID): 1570854175186519040 (CiNii: 1570854175186519040)
9.	Toshio Takayanagi : Analysis of Ion-Association Reaction in Aqueous Solution and Its Utilization by Capillary Zone Electrophoresis, Analytical Sciences, Vol.20, No.2, 255-265, Feb. 2004. (要約) Electrophoretic migration of analytes in capillary zone electrophoresis (CZE) reflects the dissolved status of analytes in solution, and the electrophoretic mobility is controlled to develop the resolution among analytes by adding a "modifier" to the migrating solution. Such addition of modifier is essentially the utilization of molecular interactions. Precise measurement of electrophoretic mobility by CZE allows analyzing molecular interactions, and CZE apparatus is very useful for physicochemical measurements. This review focuses on the advantages on using CZE to analyze equilibrium reaction; the capillary electrophoretic method and mathematical analyses that apply acid dissociation and complex formation reactions are also validated. Ion association reactions are deeply related to analytical chemistry and separation science, and CZE has been used for the investigation of ion-ion interactions. Various types of interactions have been clarified through the CZE measurements: contributions of hydrophobicity, probability, and aromatic-aromatic interaction were quantitatively evaluated. Ion association reaction in aqueous solution also elucidates the stepwise reactions of liquid-liquid distribution of ion associates. Development and applications of ion association reaction in CZE analysis are also introduced. (出版サイトへのリンク) ● Publication site (DOI): 10.2116/analsci.20.255 (文献検索サイトへのリンク) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 15055948 ● Summary page in Scopus @ Elsevier: 2-s2.0-1442338446 (DOI: 10.2116/analsci.20.255, PubMed: 15055948, Elsevier: Scopus)
10.	髙栁俊夫 : イオン移動度測定による水溶液内イオン間相互作用の精密解析, 化学と工業, Vol.55, No.2, 117-120, 2002年2月.
11.	李啓榮, 髙栁俊夫, 大島光子, 本水昌二 : キトサンキレート樹脂前濃縮/誘導結合プラズマ-質量分析法(ICP-MS)による河川水中の微量金属の同時定量, しぶかわ, Vol.20, 3-14, 2000年8月.
12.	髙栁俊夫, 本水昌二 : 水溶液内平衡反応の精密解析:キャピラリー電気泳動によるイオン移動度測定から, CEアドバンス, Vol.4, No.2, 48-60, 2000年8月.
13.	李啓榮, 大島光子, 髙栁俊夫, 本水昌二 : 誘導結合プラズマ-質量分析法による環境水中の微量金属の定量, 環境制御, Vol.21, 4-10, 1999年6月.
14.	本水昌二, 髙栁俊夫 : 高性能キャピラリー電気泳動法とその海水分析への応用, 日本海水学会誌, Vol.53, No.3, 166-179, 1999年5月.
15.	本水昌二, 髙栁俊夫 : キレート抽出とその分析化学への応用, ぶんせき, Vol.1997, No.5, 376-383, 1997年5月.
16.	髙栁俊夫 : 希土類錯体を用いたアミノ酸誘導体の分離, ぶんせき, Vol.1996, No.5, 381, 1996年5月.
17.	髙栁俊夫, 和田栄子, 大島光子, 本水昌二 : キャピラリー電気泳動法による環境試料中の無機陰イオンの定量, 環境制御, Vol.17, 49-55, 1995年6月.

国際会議:

1.	Yuka Torii, Sohei Tsugita, Yukuto Ogawa, Hiten Iwamoto, Jiro Kasahara, Masaki Takeuchi, Masamitsu Iiyama, Toshio Takayanagi and Hitoshi Mizuguchi : Dopamine monitoring in a mouse brain using a microdialysis-integrated HPLC equipped with a track-etched membrane double-electrode detector, 10th International Conference on Advanced Materials Development and Performance (AMDP2024), Tokushima, Sep. 2024.
2.	Yusuke Kita, Hashimoto Rikuo, Tomohiko Kuwabara, Kenji Matsumoto, Hiroki Hotta, Masamitsu Iiyama, Toshio Takayanagi and Hitoshi Mizuguchi : Analysis of phenolic compounds in beverages by HPLC equipped with a multi-anode cathode pair detection system, 10th International Conference on Advanced Materials Development and Performance (AMDP2024), Tokushima, Sep. 2024.
3.	Sayaka Tani, Soma Fujiki, Masatsugu Oishi, Masamitsu Iiyama, Toshio Takayanagi, Yu-Chi Lin, Min-Hsin Yeh and Hitoshi Mizuguchi : Determination of glucose in fruit juice beverages using N-GQD/NiWO4- supported track-etched membrane electrode system, 10th International Conference on Advanced Materials Development and Performance (AMDP2024), Tokushima, Sep. 2024.
4.	Hiroto Takeda, Mai Naemura, Majied Khalila Rachmasrori, Masaki Takeuchi, Kyosuke Kinoshita, Maekawa Taiga, Tomoya Ogawa, Toshio Takayanagi, Norio Teramae, William Pipkin, Atsushi Watanabe, Chuichi Watanabe and Hitoshi Mizuguchi : Analysis of airborne particulate PET by thermochemolysis-GC/MS using tetramethylammonium hydroxide, RSC-JAIMA Symposium on Analytical Chemistry 2024, Chiba, Sep. 2024.
5.	Yui Kakitani, Masamitsu Iiyama, Toshio Takayanagi and Hitoshi Mizuguchi : A novel potentiometric flow sensor for residual chlorine using activated carbon and track-etched membrane electrodes, RSC-JAIMA Symposium on Analytical Chemistry 2024, Chiba, Sep. 2024.
6.	Hitoshi Mizuguchi, Hiroto Takeda, Mai Naemura, Majied Khalila Rachmasrori, Kyosuke Kinoshita, Masaki Takeuchi, Toshio Takayanagi, Norio Teramae, William Pipkin, Atsushi Watanabe and Chuichi Watanabe : Sensitive Determination of Polyethylene Terephthalate Collected from the Air by Thermochemolysis-Gas Chromatography/Mass Spectrometry, 24th International Symposium on Analytical and Applied Pyrolysis (Pyro2024), Beijing, May 2024.
7.	Tomohiko Kuwabara, Yusuke Kita, Rikuo Hashimoto, Kenji Matsumoto, Hiroki Hotta, Masamitsu Iiyama, Toshio Takayanagi and Hitoshi Mizuguchi : Detection Pattern of Phenolic Compounds in A Multi-Electrode System Constructed with Track-Etched Membrane Electrodes-Relationship Between Molecular Structure and Collection Efficiency, 16th Asian Conference on Analytical Sciences (ASIANALYSIS XVI) 2023, Kuala Lumpur, Oct. 2023.
8.	Hitoshi Mizuguchi, Yuka Torii, Sohei Tsugita, Yukuto Ogawa, Hiten Iwamoto, Masaki Takeuchi, Masamitsu Iiyama, Toshio Takayanagi and Jiro Kasahara : A Microdialysis-Integrated HPLC System Constructed Using Track-Etched Membrane Electrodes for Dopamine Monitoring in Mouse Brain, 19th Asia-Pacific International Symposium on Microscale Separations and Analysis 2023 (APCE 2023), Kuala Lumpur, Oct. 2023.
9.	Chang Yiu-Cheng, Morita Kotaro, Hirayama Naoki, Hitoshi Mizuguchi and Toshio Takayanagi : Modification of Albumin with Carbon Nanodots and Its Analysis by Capillary Zone Electrophoresis, Royal Society of Chemistry Tokyo International Conference 2023 (RSC-TIC 2023), Chiba, Sep. 2023.
10.	Yusuke Kita, Rikuo Hashimoto, Tomohiko Kuwabara, Kenji Matsumoto, Hiroki Hotta, Masamitsu Iiyama, Toshio Takayanagi and Hitoshi Mizuguchi : Analysis of phenolic compounds in beverages by HPLC equipped with quadruple track-etched membrane electrode detection system, Royal Society of Chemistry Tokyo International Conference 2023 (RSC-TIC 2023), Chiba, Sep. 2023.
11.	Sayaka Tani, Soma Fujiki, Masatsugu Oishi, Masamitsu Iiyama, Toshio Takayanagi, Yu-Chi Lin, Min-Hsin Yeh and Hitoshi Mizuguchi : Amperometric determination of glucose using nitrogen-doped graphene/NiWO4-decorated track-etched membrane electrodes, Royal Society of Chemistry Tokyo International Conference 2023 (RSC-TIC 2023), Chiba, Sep. 2023.
12.	Yuka Torii, Sohei Tsugita, Yukuto Ogawa, Hiten Iwamoto, Jiro Kasahara, Masaki Takeuchi, Masamitsu Iiyama, Toshio Takayanagi and Hitoshi Mizuguchi : Dopamine monitoring in a mouse brain using a microdialysis-integrated HPLC equipped with a track-etched membrane double-electrode detector, Royal Society of Chemistry Tokyo International Conference 2023 (RSC-TIC 2023), Chiba, Sep. 2023.
13.	Hiroto Takeda, Kyosuke Kinoshita, Masaki Takeuchi, Toshio Takayanagi, Hajime Ohtani, Norio Teramae, William Pipkin, Atsushi Watanabe, Chuichi Watanabe and Hitoshi Mizuguchi : Highly Sensitive Analysis of Airborne Microplastics by Splitless Pyrolysis-GC/MS, Royal Society of Chemistry Tokyo International Conference 2023 (RSC-TIC 2023), Chiba, Sep. 2023.
14.	Hitoshi Mizuguchi, Daichi Tanaka, Yusuke Taniguchi, Suherman Suherman, Toshio Takayanagi and Yasutada Suzuki : Highly sensitive determination of copper by solid-phase colorimetry using a reflection colorimeter integrated with a coaxial optical fiber cable (Invited Lecture), Colloquium Spectroscopicum Internationale XLIII (43rd CSI), Tokushima, Jun. 2023.
15.	Atsushi Watanabe, Hitoshi Mizuguchi, Hiroto Takeda, Kyosuke Kinoshita, Masaki Takeuchi, Toshio Takayanagi, Hajime Ohtani, Norio Teramae, William Pipkin, Kazuko Matsui and Chuichi Watanabe : Analyzing Microplastics in Airborne Particulate Matter by Pyrolysis-GC/MS, PYROASIA Symposium 2023, Kuala Lumpur, Jun. 2023.
16.	Hitoshi Mizuguchi, Sayaka Tani, Soma Fujiki, Masatsugu Oishi, Toshio Takayanagi, Yu-Chi Lin and Min-Hsin Yeh : Flow-based glucose sensor fabricated using non-enzymatic catalysts and track-etched membrane electrodes, 22nd International Conference on Flow Injection Analysis and Related Techniques (22nd ICFIA), Marseille, May 2023.
17.	Hitoshi Mizuguchi, Soma Fujiki, Sayaka Tani, Masatsugu Oishi, Toshio Takayanagi, Masamitsu Iiyama, Lin Yu-Chi and Yeh Min-Hsin : Modification Of Track-Etched Membrane Electrodes With Non-Enzymatic Catalysts For Flow-Based Biosensors, The 9th International Forum on Advanced Technologies and The 4th Japan-Taiwan International Engineering Forum (IFAT&JTIEF2023), Mar. 2023.
18.	Hitoshi Mizuguchi, Soma FUJIKI, Masatsugu Oishi, Toshio Takayanagi, Yu-Chi LIN and Min-Hsin YEH : Electrochemical Flow System Using Track-Etched Microporous Membrane Electrodes for the Selective Detection of Uric Acid with Non-enzymatic Catalysts, 8th International Forum on Advanced Technologies (IFAT2022), Online, Mar. 2022.
19.	Yuki ASAGIRI, Tatsuro KIJIMA, Masamitsu IIYAMA, Toshio Takayanagi and Hitoshi Mizuguchi : Trach-etched membrane-based aptasensing platform for simultaneous detection of thrombin and lysozyme., The International Chemical Congress of Pacific Basin Societies 2021 (PACIFICHEM 2021), Online, Dec. 2021.
20.	Hitoshi Mizuguchi, Sohma FUJIKI, Masatsugu Oishi, Toshio Takayanagi, Jun-De ZHAN and Min-Hsin YEH : Introduction of Non-Enzymatic Catalysts on a Track-Etched Microporous Membrane Electrode for the Selective Detection of Uric Acid, 7th International Forum on Advanced Technologies (IFAT2021), Online, Mar. 2021.
21.	Rikuo HASHIMOTO, Tomohiko Kuwabara, Kenji MATSUMOTO, Hiroki HOTTA, Masamitsu IIYAMA, Toshio Takayanagi and Hitoshi Mizuguchi : Detection behavior of phenolic compounds by the dual-electrode flow-cell constructed using the track-etched microporous membrane electrodes, RSC Tokyo International Conference 2020, Online, Dec. 2020.
22.	Yuki ASAGIRI, Misaki KOBAYASHI, Tsubasa MANO, Ryoichi TANIBUCHI, Takeshi SAKAMAKI, Naoto YOSHIKAWA, Masamitsu IIYAMA, Tatsuro KIJIMA, Toshio Takayanagi and Hitoshi Mizuguchi : An electrochemical aptasensing platform constructed using track-etched microporous membrane filters, RSC Tokyo International Conference 2020, Online, Dec. 2020.
23.	Daichi Nishimori, Tomohiko Kuwabara, Masaki Takeuchi, Masamitsu Iiyama, Toshio Takayanagi and Hitoshi Mizuguchi : Determination of catecholamines by HPLC-coulometric detection using track-etched microporous membrane electrodes, RSC-Tokyo International Conference 2019, Chiba, Sep. 2019.
24.	Hitoshi Mizuguchi, Genya Umeda, (名) Suherman, Toshio Takayanagi and Kinichi Morita : On-site determination of trace nickel(II) in water samples by the combination of a simple enrichment technique with a handheld spectrometer, The Pittsburgh Conference 2019 (Pittcon 2019), Philadelphia, Mar. 2019.
25.	Hitoshi Mizuguchi, Daichi Nishimori, Masamitsu Iiyama, Masaki Takeuchi and Toshio Takayanagi : High-performance liquid chromatography with a dual-electrode detector constructed using track-etched microporous membrane electrodes, 14th International Conference on Flow Analysis (Flow Analysis XIV), Bangkok, Dec. 2018.
26.	Hitoshi Mizuguchi, Genya Umeda, (名) Suherman, Toshio Takayanagi and Kinichi Morita : Combination of a preconcentration technique with a handheld spectrometer for on-site determination of trace nickel with alpha-Furil Dioxime, 14th International Conference on Flow Analysis (Flow Analysis XIV), Bangkok, Dec. 2018.
27.	Masanori Mine, Hitoshi Mizuguchi and Toshio Takayanagi : Kinetic Analysis of Enzymatic Reaction of Alkaline Phosphatase by In-capillary Dynamic Reaction, RSC Tokyo International Conference 2018, Chiba, Sep. 2018.
28.	Daichi Nishimori, Masaki Takeuchi, Masamitsu Iiyama, Toshio Takayanagi and Hitoshi Mizuguchi : High Performance liquid chromatography-electrochemical detection using track-etched microporous membrane electrodes, RSC Tokyo International Conference 2018, Chiba, Sep. 2018.
29.	Ito Daichi and Toshio Takayanagi : Analysis of Acid - Base Equilibrium of Bupropion under Degradation Conditions by Capillary Zone Electrophoresis, RSC Tokyo International Conference, Chiba, Sep. 2017.
30.	Ishida Ryota, Kouno Yasushi, Tachibana Tadahiko, Honda Tomomi, Kijima Tatsuro, Toshio Takayanagi and Hitoshi Mizuguchi : Simple Colorimetric Detection of Ultra-trace Ni(II) and Cu(II) Followed by Rapid Enrichment Using a Nanofiber-composite Membrane Filter, RSC Tokyo International Conference, Chiba, Sep. 2017.
31.	Masashi Kurashina, Daiki Ikeuchi, Masaki Ohara, Toshio Takayanagi and Mikito Yasuzawa : Syntheses and Properties of Copper Hydroxide Nanosheets and Controlled Deposition, International Conference on Advanced Materials Development and Performance 2017, Pune, Jul. 2017.
32.	Hitoshi Mizuguchi, Keiko Sasaki, Hirokazu Ichinose, Shota Seino, Jun Sakurai, Masamitsu Iiyama, Tatsuro Kijima, Kazuhiro Tachibana, Tatsuo Nishina, Toshio Takayanagi and Junichi Shida : Simultaneous detection system for L-lactate and D-glucose using track-etched microporous membrane electrodes, ASIANALYSIS XIII, Chiang Mai, Dec. 2016.
33.	Toshio Takayanagi, Masaki Morimoto, Yuki Tomiyama and Tomoki Yabutani : Micellar electrokinetic chromatography of graphenes, PACIFICHEM 2015, Hawaii, USA, Dec. 2015.
34.	Toshio Takayanagi, Ayumi Kimura, Keisuke Matsumoto and Tomoki Yabutani : Spectrophotometric flow injection analyses for the inhibitory assay of xanthine oxidase and the assay of oxidant scavenging capacity, PACIFICHEM 2015, Hawaii, USA, Dec. 2015.
35.	Toshio Takayanagi : Determination of acid dissociation constants of phenolphthalein and its derivatives under degradation, PACIFICHEM 2015, Hawaii, USA, Dec. 2015.
36.	Toru Takahashi, Akihiro Hosono, Toshio Takayanagi and Nobuhiko Iki : Kinetic Analysis of Acidic and Basic Hydrolysis of Tetrabromophenolphthalein Ethyl Ester by Zone-passing Mode Capillary Electrophoretic Reactor, 14th Asia-Pacific International Symposium on Microscale Separations and Analysis, Kyoto, Dec. 2014.
37.	Toshio Takayanagi, Yuki Tomiyama, Masaki Morimoto and Tomoki Yabutani : Micellar Electrokinetic Chromatography of Graphenes with Polymer Additive, 14th Asia-Pacific International Symposium on Microscale Separations and Analysis, Kyoto, Dec. 2014.
38.	Natsumi Shimakami, Tomoki Yabutani and Toshio Takayanagi : Determination of Acid Dissociation Constant of Haloperidol under Photo-degraded Conditions through the Measurement of Electrophoretic Mobility by Capillary Zone Electrophoresis, 14th Asia-Pacific International Symposium on Microscale Separations and Analysis, Kyoto, Dec. 2014.
39.	Ayumi Kimura, Tomoki Yabutani and Toshio Takayanagi : Inhibitor Assay of Xanthine Oxidase by Photometric Flow Injection Analysis with Bindschedler's Green Leuco Base, RSC Tokyo International Conference, JASIS Conference, Chiba, Sep. 2014.
40.	Yohei Yamada, Yuki Ohnishi, Mari Nakashima, Katsuhito Tanaka, Toshio Watanabe, Haruhiko Sakuraba, Toshio Takayanagi and Tomoki Yabutani : Amperometric Determination of Branched Amino Acids by High Performance Liquid chromatograph with L-leusine Dehydrogenase / Diapholase Immobilized Electrode as A Detector, RSC Tokyo International Conference 2013 - Analytical Biochemistry & Biophysics -, Chiba, Sep. 2013.
41.	Toshio Takayanagi : Aquatic Analysis of Bromate Ion and Perfluorinated Surfactants on the Basis of Photometric Detection for Environmentally Friendly Analysis, 2013 CJK Symposium The 10th China-Japan-Korea Symposium on Analytical Chemistry /ASIANALYSIS XII, Aug. 2013.
42.	Tomoki Yabutani, Chihiro Mukuta, Masashi Konishi, Yohei Yamada and Toshio Takayanagi : Selective Separation of Oxoanion-Forming Elements Adsorbed on Solid States by Using Hydrogen Peroxide as Eluent, ASIANALYSIS XII The Twelfth Asian Conference on Analytical Sciences, Fukuoka, Aug. 2013.
43.	Toshio Takayanagi, Masaki Morimoto and Tomoki Yabutani : Micellar Electrokinetic Chromatography of Graphene and Chemically Modified Graphene, ASIANALYSIS XII The Twelfth Asian Conference on Analytical Sciences, Fukuoka, Aug. 2013.
44.	Yuji Inoi, Ayumi Kimura, Tomoki Yabutani and Toshio Takayanagi : Fluorimetric Determination of Hexavalent Chromate Ion Using 2,3-Diaminonaphthalene and Hydroxylamine Hydrochroride, ASIANALYSIS XII The Twelfth Asian Conference on Analytical Sciences, Fukuoka, Aug. 2013.
45.	Shinji Nishimae, Yoshihumi Isobe, Tomoki Yabutani, Toshio Takayanagi, Tomohiro Hirano and Koichi Ute : Poyion Complxes Formed between Hyper-branched Polyelectrolytes Synthesized by Ininiator-Fragment Incorporation Radical Polymerization Method, ASIANALYSIS XII The Twelfth Asian Conference on Analytical Sciences, Fukuoka, Aug. 2013.
46.	Toshio Takayanagi, Kinuyo Ogura and Tomoki Yabutani : Ion-Association Analysis of Dipicrylaminate Ion in an Aqueous Solution by Capillary Zone Electrophoresis, ASIANALYSIS XII The Twelfth Asian Conference on Analytical Sciences, Fukuoka, Aug. 2013.
47.	Takashi Kaneta, Genki Inoue, Toshio Takayanagi, Junichi Kakehi, Hiroyasu Motose and Taku Takahashi : Determination of Polyamines in Arabidopsis by Capillary Electrophoresis using Salicylaldehyde-5-sulfonate as a Derivatizing Reagent, 19th International Symposium, Exhibit & Workshops on Electro- and Liquid Phase-separation Techniques, Baltimore Inner Harbor Maryland, USA, Oct. 2012.
48.	Yohei Yamada, Shota Toyama, Takahito Suzuta, James Metson, David Williams, Yoshihisa Suzuki, Tomoki Yabutani and Toshio Takayanagi : Characterization of penetration of metallic oxide precursor into ferritin crystal as a template for highly orderedmesoporous materials, JAIMA Discussion on Analytical Science and Technology 2012, The Royal Society of Chemistry Tokyo International Conference 2012, Chiba, Sep. 2012.
49.	Kanae Ueda and Toshio Takayanagi : Ion-association Analysis of Tetraphenylborate Ions by Capillary Zone Electrophoresis, ICAS2011, Kyoto, May 2011.
50.	Toshio Takayanagi and Hiroyuki Kanzaki : Extraction of Constituent Spectra by Multivariate Analysis of Color Reactions on Acid-base Indicators, ICAS2011, Kyoto, May 2011.
51.	Toshio Takayanagi, Tian-Hua Han, Mitsuko Oshima and Shoji Motomizu : Spectrophotometric Flow Injection Analysis of Chromium (VI) Coupled with On-line Solid-phase Extraction with Anion-exchange Resin Cartridge, ICAS2011, Kyoto, May 2011.
52.	Toshio Takayanagi and Ayumi Ikuta : Binding and distribution analyses of organic cations to nonionic surfactant micelles in an aqueous solution through the changes in electrophoretic mobility, PACIFICHEM 2010, Honolulu, Dec. 2010.
53.	Toshio Takayanagi, Mayu Nakaya, Hiroki Yamashita, Mitsuko Oshima and Shoji Motomizu : Fluorimetric Flow Injection Analysis of Fluoride Ion with Alkylsilylated Fluoresceins, PACIFICHEM 2010, Honolulu, Dec. 2010.
54.	Toshio Takayanagi : Design of Flow Injection Analysis to Realize Green Chemistry, 2009 China-Japan-Korea Symposium on Analytical Chemistry, Chiba, Sep. 2009.
55.	Toshio Takayanagi, Y. Inaba, H. Kanzaki, Y. Jyoichi and S. Motomizu : Catalytic effect of metal ions on chemiluminometric sequential injection analysis with luminol - H2O2 system, ICFIA 2008, Nagoya, Sep. 2008.
56.	Toshio Takayanagi, M. Nishiuchi, M. Ousaka, M. Oshima and S. Motomizu : Monitoring of vitamin C species in aqueous solution by flow injection analysis coupled with an on-line separation with reversed-phase column, ICFIA 2008, Nagoya, Sep. 2008.
57.	Toshio Takayanagi, H. Yamashita, S. Motomizu, J. Musijowski and M. Trojanowicz : Determination of Perfluorinated Carboxylic Acids by Fluorimetric Flow Injection Analysis of Fluoride Ion after Preconcentration and Decomposition on An Activated Charcoal Cartridge, International Symposium on Flow-Based Analysis V, Chiang Mai, Thailand, Dec. 2007.
58.	Toshio Takayanagi and S. Motomizu : Ion-Association Extraction of Some Aromatic Anions with Tetrabutylammonium Ion into Nonionic Surfactant Micelle, APCE2006, Kyoto, Nov. 2006.
59.	Toshio Takayanagi, M. Ishida and S. Motomizu : Determination of Bromate Ion in Drinking Water by Capillary Zone Electrophoresis with Direct Photometric Detection, APCE2006, Kyoto, Nov. 2006.
60.	Toshio Takayanagi and S. Motomizu : Nonionic surfactant micelle as a pseudo-homogeneous extraction medium for the extraction of ion-associates and its application in capillary zone electrophoretic separation, PACIFICHEM 2005, Honolulu, Dec. 2005.
61.	Toshio Takayanagi : Utilization of ion-ion interactions in aqueous solution for developing resolution of anionic isomers by capillary zone electrophoresis, 3rd Singapore International Chemical Conference, Singapore, Dec. 2003.
62.	Toshio Takayanagi and S. Motomizu : Equilibrium Analysis on Distribution of Phenol Derivatives in Nonionic Surfactant Micelle - Capillary Zone Electrophoresis, ICAS2001, Tokyo, Aug. 2001.
63.	Toshio Takayanagi, I. Ikeda and S. Motomizu : Complex Formation Analysis of Crown Ethers with Metal Ions through Change in Retention Factors in Reversed Phase - High Performance Liquid Chromatography, ICAS2001, Tokyo, Aug. 2001.
64.	Toshio Takayanagi : Investigation of ion - ion interactions in an aqueous solution through electrophoretic mobility, ASIANALYSIS VI, Tokyo, Aug. 2001.
65.	Toshio Takayanagi, K. Fushimi and S. Motomizu : Separation of Isomeric Aromatic Anions by Ion Association - Micelle Distribution Capillary Zone Electrophoresis, HPCE2001, Boston, Jan. 2001.
66.	Toshio Takayanagi and S. Motomizu : Equilibrium Analysis of Acid Dissociation Reactions of Phenolphthalein by Using Mobility Change in Capillary Zone Electrophoresis, HPCE2001, Boston, Jan. 2001.
67.	Toshio Takayanagi, K. Fushimi and S. Motomizu : Capillary Electrophoretic Separation of Isomeric Aromatic Anions Based on Ion Association and Distribution to Nonionic Surfactant Micelle, PACIFICHEM 2000, Honolulu, Dec. 2000.
68.	Toshio Takayanagi and S. Motomizu : Utilization of Ion Association Reaction for Resolution Improvements of Anionic Positional Isomers by Capillary Zone Electrophoresis, PACIFICHEM 2000, Honolulu, Dec. 2000.
69.	Toshio Takayanagi, E. Wada, Y. Hiroi and S. Motomizu : Separation and Determination of Nitrogen, Phosphorous and Sulfur Oxides in Environmental Water Samples by Capillary Zone Electrophoresis, PACIFICHEM 2000, Honolulu, Dec. 2000.
70.	Toshio Takayanagi and S. Motomizu : Equilibrium Analysis of Reactions between Aromatic Anions and Nonionic Surfactant Micelles by Capillary Zone Electrophoresis, HPCE'99, Palm Springs, USA, Jan. 1999.
71.	S. Motomizu and Toshio Takayanagi : Electrophoretic Study of Ion - Ion Interaction in Aqueous Solution, HPCE'99, Palm Springs, USA, Jan. 1999.
72.	Toshio Takayanagi, E. Wada and S. Motomizu : Analysis of Ion Association Reaction between Quaternary Ammonium Ions and Organic Anions by Capillary Zone Electrophoresis, HPCE Kyoto, Kyoto, Jul. 1997.
73.	Toshio Takayanagi and T. Yotsuyanagi : Extraction kinetics of ytterbium(III) with acidic 4-acyl-5-pyrazolones, PACIFICHEM '95, Honolulu, Dec. 1995.
74.	Toshio Takayanagi, M. Ejiri and S. Motomizu : Color fading dynamics of cationic dyes at liquid-liquid interface, PACIFICHEM '95, Honolulu, Dec. 1995.

国内講演発表:

1.	瀬戸美菜萌, 廣瀬大輝, 岡部浩隆, 松田直樹, 水口仁志, 髙栁俊夫 : チオール修飾した金ナノ粒子のキャピラリー電気泳動における泳動挙動, 第35 回クロマトグラフィ―科学会議, 2024年11月.
2.	竹田大登, 苗村真依, KHALILA MAJIED RACHMASRORI, 竹内政樹, 木下京輔, 前川大河, 小川智也, 髙栁俊夫, 寺前紀夫, William Pipkin, 渡辺壱, 渡辺忠一, 水口仁志 : 水酸化テトラメチルアンモニウムを用いる反応熱分解 GC/MS による大気中の微量 PET の定量, 第29回高分子分析討論会, 2024年10月.
3.	谷彩楓, 藤木壮磨, 大石昌嗣, 飯山真充, 髙栁俊夫, Yu-Chi Lin, Min-Hsin Yeh, 水口仁志 : N-GQD/NiWO4を担持したトラックエッチ膜フィルター電極システムを用いた果汁飲料中のグルコース検出, 日本分析化学会第73年会, 2024年9月.
4.	喜多佑輔, 橋本陸央, 桑原知彦, 松本健嗣, 堀田弘樹, 飯山真充, 髙栁俊夫, 水口仁志 : トラックエッチ膜フィルターを用いたマルチ陽極陰極ペア検出 HPLCによる飲料中フェノール化合物の分析, 日本分析化学会第73年会, 2024年9月.
5.	竹田大登, 苗村真依, KHALILA MAJIED RACHMASRORI, 竹内政樹, 木下京輔, 前川大河, 小川智也, 髙栁俊夫, 寺前紀夫, WIlliam PIPKIN, 渡辺壱, 渡辺忠一, 水口仁志 : 水酸化テトラメチルアンモニウムを用いる反応熱分解 GC/MSによる大気粉塵中の PETの分析, 日本分析化学会第73年会, 2024年9月.
6.	水口仁志, 竹田大登, 苗村真依, KHALILA MAJIED RACHMASRORI, 竹内政樹, 木下京輔, 前川大河, 髙栁俊夫, 寺前紀夫, Willam Pipkin, 渡辺壱, 渡辺忠一 : 大気マイクロプラスチック分析への反応熱分解GC/MSの適用, マテリアルライフ学会第35回研究発表会, 2024年7月.
7.	髙栁俊夫, 後藤田佳連, 峯大典, 水口仁志 : 電気泳動媒介微量分析によるアルカリフォスファターゼの酵素反応における諸因子の効果, 第31回クロマトグラフィーシンポジウム, 2024年6月.
8.	野本明日香, 峯大典, 水口仁志, 髙栁俊夫 : キャピラリー電気泳動/動的前端分析下でのアルカリフォスファターゼの酵素反応に関するシミュレーション, 第84回分析化学討論会, 2024年5月.
9.	山崎稜太, 髙栁俊夫, 上原伸夫, 水口仁志 : 吸光光度法による鉄鋼材料中の微量ケイ素およびタングステンの測定技術の化学的検証, 第84回分析化学討論会, 2024年5月.
10.	瀬戸美菜萌, 廣瀬大輝, 岡部浩隆, 松田直樹, 水口仁志, 髙栁俊夫 : キャピラリー電気泳動法によるチオール修飾した金ナノ粒子のキャラクタリゼーション, 第43回キャピラリー電気泳動シンポジウム, 2023年11月.
11.	廣瀬大輝, 岡部浩隆, 松田直樹, 水口仁志, 髙栁俊夫 : キャピラリー電気泳動法を用いた白金ナノ粒子と銀ナノ粒子の特性評価, 第43回キャピラリー電気泳動シンポジウム, 2023年11月.
12.	喜多佑輔, 橋本陸央, 桑原知彦, 松本健嗣, 堀田弘樹, 飯山真充, 髙栁俊夫, 水口仁志 : トラックエッチ膜フィルター電極を用いたアノード・カソードペア検出によるHPLCシステム, 第59回フローインジェクション分析講演会, 2023年11月.
13.	垣谷柚衣, 飯山真充, 髙栁俊夫, 水口仁志 : 電極間に吸着剤収納構造を有するフロー型次亜塩素酸センシングシステムの開発, 第59回フローインジェクション分析講演会, 2023年11月.
14.	鳥井優花, 次田宗平, 小川起人, 岩本緋天, 笠原二郎, 竹内政樹, 飯山真充, 髙栁俊夫, 水口仁志 : トラックエッチ膜フィルター二重電極を用いる微小透析/HPLCシステムー脳内ドーパミンモニタリングシステムの開発ー, 第59回フローインジェクション分析講演会, 2023年11月.
15.	野本明日香, 峯大典, 水口仁志, 髙栁俊夫 : CE/DFAにおけるアルカリホスファターゼの酵素反応および阻害反応のシミュレーション, 第59回フローインジェクション分析講演会, 2023年11月.
16.	谷彩楓, 藤木壮磨, 大石昌嗣, 飯山真充, 髙栁俊夫, Yu-Chi Lin, Min-Hsin Yeh, 水口仁志 : トラックエッチ膜フィルター電極システムの高機能化 ∼エンザイムフリーバイオセンサの選択性向上とグルコース検出∼, 第59回フローインジェクション分析講演会, 2023年11月.
17.	次田宗平, 鳥井優花, 小川起人, 岩本緋天, 笠原二郎, 竹内政樹, 飯山真充, 髙栁俊夫, 水口仁志 : トラックエッチ膜電極を用いるHPLC/電量検出法によるドーパミン放出挙動のin vivoモニタング, 第59回フローインジェクション分析講演会, 2023年11月.
18.	竹田大登, 苗村真依, 木下京輔, 竹内政樹, 髙栁俊夫, 寺前紀夫, William Pipkin, 渡辺壱, 渡辺忠一, 水口仁志 : スプリットレス熱分解GC/MSによる大気マイクロプラスチックの高感度分析法の開発, 第59回フローインジェクション分析講演会, 2023年11月.
19.	次田宗平, 鳥井優花, 小川起人, 岩本緋天, 笠原二郎, 竹内政樹, 飯山真充, 髙栁俊夫, 水口仁志 : トラックエッチ膜電極を用いるHPLC/電量検出法によるin vivoモニタリング -マウス線条体でのドーパミンの放出制御の観測-, 2023年日本化学会中国四国支部大会山口大会, 2023年11月.
20.	竹田大登, 木下京輔, 竹内政樹, 髙栁俊夫, 大谷肇, 寺前紀夫, Pipkin William, 松井和子, 渡辺壱, 渡辺忠一, 水口仁志 : スプリットレス熱分解GC/MSによる大気中の微量マイクロプラスチック分析における測定感度の向上について, 第28回高分子分析討論会, 2023年11月.
21.	谷彩楓, 藤木壮磨, 大石昌嗣, 飯山真充, 髙栁俊夫, Yu-Chi Lin, Min-Hsin Yeh, 水口仁志 : 窒素ドープグラフェン/NiWO4を担持したトラックエッチ膜電極システムを用いるグルコースセンサ, 化学とマイクロ・ナノシステム学会第48研究会, 2023年11月.
22.	野本明⽇⾹, 水口仁志, 髙栁俊夫 : キャピラリー電気泳動/動的前端分析による酵素反応阻害のシミュレーション, 日本分析化学会第72年会, 2023年9月.
23.	垣谷柚衣, 飯山真充, 髙栁俊夫, 水口仁志 : トラックエッチ膜フィルター電極を用いる吸着剤挟み込み型フローセンサの開発, 日本分析化学会第72年会, 2023年9月.
24.	鳥井優花, 次田宗平, 小川起人, 岩本緋天, 笠原二郎, 竹内政樹, 飯山真充, 髙栁俊夫, 水口仁志 : トラックエッチ膜フィルター二重電極を用いたHPLCおよび微小透析による脳内ドーパミンモニタリングシステムの開発, 第25回活性アミンに関するワークショップ, 2023年8月.
25.	竹田大登, 木下京輔, 竹内政樹, 髙栁俊夫, 大谷肇, 寺前紀夫, William Pipkin, 松井和子, 渡辺壱, 渡辺忠一, 水口仁志 : 大気マイクロプラスチック分析へのスプリットレス熱分解GC/MSの適用, マテリアルライフ学会第34回研究発表会, 2023年7月.
26.	張友政, 森田耕太郎, 平山直紀, 水口仁志, 髙栁俊夫 : カーボンナノドットを用いたアルブミンの修飾とCZE検出, 第30回クロマトグラフィーシンポジウム, 2023年6月.
27.	瀬戸美菜萌, 廣瀬大輝, 岡部浩隆, 松田直樹, 水口仁志, 髙栁俊夫 : キャピラリー電気泳動法によるL-システイン修飾した金ナノ粒子のキャラクタリゼーション, 第30回クロマトグラフィーシンポジウム, 2023年6月.
28.	髙栁俊夫, 岡崎吏紗, 峯大典, 水口仁志 : キャピラリー電気泳動/動的前端分析においてプラトー応答を生じる諸因子の検討, --- -アルカリフォスファターゼによるリン酸エステル加水分解反応から- ---, 第30回クロマトグラフィーシンポジウム, 2023年6月.
29.	志水裕哉, 峯大典, 水口仁志, 髙栁俊夫 : キャピラリー電気泳動/動的前端分析によるヒポキサンチンの二段階酵素酸化反応の解析, 第83回分析化学討論会, 2023年5月.
30.	鳥井優花, 小川起人, 次田宗平, 佐藤采, 岩本緋天, 笠原二郎, 竹内政樹, 飯山真充, 髙栁俊夫, 水口仁志 : トラックエッチ膜フィルター電極を用いたHPLCおよび微小透析法によるマウス線条体でのドーパミン放出挙動の解析, 第83回分析化学討論会, 2023年5月.
31.	喜多佑輔, 橋本陸央, 桑原知彦, 松本健嗣, 堀田弘樹, 飯山真充, 髙栁俊夫, 水口仁志 : トラックエッチ膜フィルターを用いた四重電極検出器でのフェノール化合物の検出挙動, 第83回分析化学討論会, 2023年5月.
32.	竹田大登, 木下京輔, 竹内政樹, 髙栁俊夫, 大谷肇, 寺前紀夫, Pipkin William, 松井和子, 渡辺壱, 渡辺忠一, 水口仁志 : スプリットレス熱分解GC/MSによる大気マイクロプラスチックの分析, 第83回分析化学討論会, 2023年5月.
33.	谷彩楓, 藤木壮磨, 大石昌嗣, 飯山真充, 髙栁俊夫, Yu-Chi Lin, Min-Hsin Yeh, 水口仁志 : 窒素ドープグラフェン/NiWO<sub>4</sub>修飾型トラックエッチ膜フィルター電極の作製とグルコースセンサへの展開, 第83回分析化学討論会, 2023年5月.
34.	小川起人, 次田宗平, 鳥井優花, 佐藤采, 岩本緋天, 笠原二郎, 竹内政樹, 飯山真充, 髙栁俊夫, 水口仁志 : マウス線条体ドーパミンのin vivo測定のためのHPLC/トラックエッチ膜電量検出装置の開発, 第58回フローインジェクション分析講演会, 2022年11月.
35.	藤木壮磨, 大石昌嗣, Masamitsu Iiyama, 髙栁俊夫, Jun-De Zhan, Min-Hsin Yeh, 水口仁志 : トラックエッチ膜フィルター電極システムに基づく非酵素型フローセンサによる尿酸の検出, 第58回フローインジェクション分析講演会, 2022年11月.
36.	喜多佑輔, 橋本陸央, 桑原知彦, 松本健嗣, 堀田弘樹, 飯山真充, 髙栁俊夫, 水口仁志 : トラックエッチ膜フィルターを用いた四重電極検出器によるHPLCシステム, 第58回フローインジェクション分析講演会, 2022年11月.
37.	鳥井優花, 小川起人, 次田宗平, 岩本緋天, 佐藤采, 笠原二郎, 竹内政樹, 飯山真充, 髙栁俊夫, 水口仁志 : 微小透析およびHPLCによるマウス線条体でのドーパミン放出挙動の解析, 第58回フローインジェクション分析講演会, 2022年11月.
38.	谷彩楓, 藤木壮磨, 大石昌嗣, 飯山真充, 髙栁俊夫, Jun-De Zhan, Min-Hsin Yeh, 水口仁志 : トラックエッチ膜フィルター電極への窒素ドープグラフェン/NiWO4の修飾とFIA法によるアンペロメトリー測定, 第58回フローインジェクション分析講演会, 2022年11月.
39.	垣谷柚衣, 藤木壮磨, 飯山真充, 髙栁俊夫, 水口仁志 : トラックエッチ膜フィルター電極とイオン交換樹脂を用いる新しいフローセンサの提案, 第58回フローインジェクション分析講演会, 2022年11月.
40.	次田宗平, 小川起人, 鳥井優花, 佐藤采, 岩本緋天, 笠原二郎, 竹内政樹, 飯山真充, 髙栁俊夫, 水口仁志 : トラックエッチ膜フィルター二重電極を検出器とするキャピラリーHPLCによるマウス脳内ドーパミンのin vivo測定, 第58回フローインジェクション分析講演会, 2022年11月.
41.	北條三奈, 河野俊貴, 棚田智大, 飯山真充, 髙栁俊夫, 水口仁志 : 紫外線照射下での光分解反応の速度差を利用する遊離塩素と結合塩素のFIA分別定量, 第58回フローインジェクション分析講演会, 2022年11月.
42.	竹田大登, 木下京輔, 竹内政樹, 髙栁俊夫, 大谷肇, 寺前紀夫, Pipkin William, 松井和子, 渡辺壱, 渡辺忠一, 水口仁志 : 熱分解 GC/MS による大気粉塵中のプラスチック成分の分析, 2022年日本化学会中国四国支部大会, 2022年11月.
43.	北條三奈, 河野俊貴, 棚田智大, 飯山真充, 髙栁俊夫, 水口仁志 : 光分解反応速度差による遊離塩素と結合塩素のFIA分別定量, 2022年日本化学会中国四国支部大会広島大会, 2022年11月.
44.	小川起人, 次田宗平, 鳥井優花, 佐藤采, 岩本緋天, 笠原二郎, 竹内政樹, 飯山真充, 髙栁俊夫, 水口仁志 : トラックエッチ膜電極を用いるHPLC/電量検出法によるマウス線条体ドーパミンのin vivoモニタリング, 2022年日本化学会中国四国支部大会広島大会, 2022年11月.
45.	藤木壮磨, 大石昌嗣, 髙栁俊夫, Zhan Jun-De, Yeh Min-Hsin, 水口仁志 : トラックエッチ膜フィルター電極システムに基づく非酵素型尿酸センサの開発, 2022年日本化学会中国四国支部大会広島大会, 2022年11月.
46.	藤木壮磨, 大石昌嗣, 髙栁俊夫, Zhan Jun-De, Yeh Min-Hsin, 水口仁志 : トラックエッチ膜フィルター電極を積層させた非酵素型センサによる尿酸の高感度検出, 第68回ポーラログラフィーおよび電気分析化学討論会, 2022年11月.
47.	水口仁志, 竹田大登, 木下京輔, 竹内政樹, 髙栁俊夫, 大谷肇, 寺前紀夫, Pipkin William, 松井和子, 渡辺壱, 渡辺忠一 : 石英繊維フィルターに捕集した大気マイクロプラスチックの熱分解GC/MSによる分析, 第27回高分子分析討論会, 2022年10月.
48.	水口仁志, 竹田大登, 木下京輔, 竹内政樹, 髙栁俊夫, 大谷肇, 寺前紀夫, William Pipkin, 松井和子, 渡辺忠一 : 熱分解 GC/MSによる分級捕集した大気浮遊マイクロプラスチックの分析, 日本分析化学会第71年会, 2022年9月.
49.	谷口友亮, 田中大地, SUHERMAN Suherman, 鈴木保任, 髙栁俊夫, 水口仁志 : 同軸光ファイバケーブルを搭載したポータブル反射型比色計を用いる銅イオンの高感度分析, 日本分析化学会第71年会, 2022年9月.
50.	玉置隆成, 水口仁志, 髙栁俊夫 : キャピラリー電気泳動/前端分析における薬物-タンパク結合のシミュレーション, 日本分析化学会第71年会, 2022年9月.
51.	廣瀬大輝, 岡部浩隆, 松田直樹, 水口仁志, 髙栁俊夫 : キャピラリーゾーン電気泳動法を用いた白金ナノ粒子と銀ナノ粒子の分散安定性の評価, 第29回クロマトグラフィーシンポジウム, 2022年6月.
52.	野本明日香, 水口仁志, 髙栁俊夫 : キャピラリー電気泳動/動的前端分析における酵素反応のシミュレーション, 第29回クロマトグラフィーシンポジウム, 2022年6月.
53.	次田宗平, 小川起人, 佐藤采, 岩本緋天, 笠原二郎, 竹内政樹, 飯山真充, 髙栁俊夫, 水口仁志 : トラックエッチ膜フィルター二重電極を検出器とする微小透析法-HPLCによるドーパミンのin vivo測定, 第82回分析化学討論会, 2022年5月.
54.	髙栁俊夫 : 分離キャピラリー内での反応ダイナミクスに基づく新しい反応・物性解析法の開発, 第32回クロマトグラフィー科学会議, 2021年11月.
55.	藤木壮磨, 大石昌嗣, 髙栁俊夫, Jun-De ZHAN, Min-Hsin YEH, 水口仁志 : トラックエッチ膜フィルターを母体とする積層型電極システムを用いる尿酸の高感度検出, 第67回ポーラログラフィーおよび電気分析化学討論会, 2021年11月.
56.	三宅晃嗣, 岡部浩隆, 松田直樹, 水口仁志, 髙栁俊夫 : キャピラリーゾーン電気泳動法によるSP 法で合成された金ナノ粒子の水溶液中における分散安定性の観察, クロマトグラフィー次世代技術セミナー2021, 2021年10月.
57.	髙栁俊夫, 峯大典 : キャピラリー電気泳動/動的前端分析法の開発と展開, クロマトグラフィー次世代技術セミナー2021, 2021年10月.
58.	小川起人, 佐藤采, 岩本緋天, 笠原二郎, 竹内政樹, 飯山真充, 髙栁俊夫, 水口仁志 : 微小透析法-キャピラリーHPLC-トラックエッチ膜フィルター電量検出装置の開発と脳内ドーパミンのin situ測定, 日本分析化学会第70年会, 2021年9月.
59.	藤木壮磨, 大石昌嗣, 髙栁俊夫, Jun-De Zhan, Min-Hsin Yeh, 水口仁志 : アセチレンブラック修飾型トラックエッチ膜フィルター電極を用いる高感度尿酸センサーの開発, 日本分析化学会第70年会, 2021年9月.
60.	北條三奈, 河野俊貴, 棚田智大, 飯山真充, 髙栁俊夫, 水口仁志 : フローインジェクション分析による紫外線照射下での光分解反応速度差に基づく遊離塩素と結合塩素の分別定量, 日本分析化学会第70年会, 2021年9月.
61.	橋本陸央, 桑原知彦, 松本健嗣, 堀田弘樹, 飯山真充, 髙栁俊夫, 水口仁志 : トラックエッチ膜フィルターを用いるHPLC-二重電極検出-フェノール系化合物の捕捉率について-, 日本分析化学会第70年会, 2021年9月.
62.	朝桐佑記, 小林美咲, 眞野翼, 谷渕諒一, 酒巻武史, 吉川直人, 木島龍朗, 飯山真充, 髙栁俊夫, 水口仁志 : トラックエッチ膜フィルター電極を用いる積層型アプタセンサーの開発とトロンビンおよびリゾチームの同時検出への応用, 日本分析化学会第70年会, 2021年9月.
63.	三宅晃嗣, 岡部浩隆, 松田直樹, 水口仁志, 髙栁俊夫 : キャピラリー電気泳動法を用いたアルカンジチオールによる金ナノ粒子二量体形成の観察, 日本分析化学会第70年会, 2021年9月.
64.	志水裕哉, 峯大典, 水口仁志, 髙栁俊夫 : キャピラリー電気泳動/動的前端分析によるピルビン酸キナーゼの酵素反応の解析, 第28回クロマトグラフィーシンポジウム, 2021年6月.
65.	峯大典, 水口仁志, 髙栁俊夫 : キャピラリー電気泳動/動的前端分析を用いたチロシナーゼによるチロシンの二段階酸化の速度論解析, 第28回クロマトグラフィーシンポジウム, 2021年6月.
66.	水口仁志, 谷口友亮, SUHERMAN Suherman, 森田金市, 髙栁俊夫, 鈴木保任 : 同軸光ファイバーケーブルを搭載した反射型比色計を用いる高感度な固相比色分析, 第81回分析化学討論会, 2021年5月.
67.	三宅晃嗣, 岩崎颯太, 岡部浩隆, 松田直樹, 水口仁志, 髙栁俊夫 : キャピラリーゾーン電気泳動法を用いる液相プラズマ法で合成した金ナノ粒子の分散安定性評価, 40周年記念キャピラリー電気泳動シンポジウム, 2020年11月.
68.	峯大典, 水口仁志, 髙栁俊夫 : キャピラリー電気泳動/動的前端分析によるクレアチンキナーゼのリン酸基転移反応解析, 40周年記念キャピラリー電気泳動シンポジウム, 2020年11月.
69.	水口仁志, 橋本陸央, 桑原知彦, 松本健嗣, 堀田弘樹, 飯山真充, 髙栁俊夫 : トラックエッチ膜フィルターに基づく直列型二重電極を用いる流れ条件下におけるフェノール類の検出挙動, 第66回ポーラログラフィーおよび電気分析化学討論会, 2020年11月.
70.	谷上裕紀, 水口仁志, 髙栁俊夫 : キャピラリーゾーン電気泳動法を用いたアスコルビン酸の二段階の酸解離平衡の解析, 第31回クロマトグラフィー科学会議, 2020年11月.
71.	橋本陸央, 桑原知彦, 松本健嗣, 堀田弘樹, 飯山真充, 髙栁俊夫, 水口仁志 : トラックエッチ膜フィルター二重電極フローセルにおけるフェノール系化合物の検出挙動-分子構造との関係-, 日本分析化学会第69年会, 2020年9月.
72.	岩崎颯太, 森田耕太郎, 平山直紀, 水口仁志, 髙栁俊夫 : 電気炉加熱分解法により合成された親水性カーボンナノドットのキャピラリー電気泳動法による特性評価, 第27回クロマトグラフィーシンポジウム, 2020年6月.
73.	峯大典, 松本直也, 水口仁志, 髙栁俊夫 : キャピラリー電気泳動/動的前端分析によるカルボキシルエステラーゼの酵素反応解析, 第27回クロマトグラフィーシンポジウム, 2020年6月.
74.	谷口友亮, (名) Suherman, 鈴木保任, 森田金市, 髙栁俊夫, 水口仁志 : ルアーロック式光ファイバーセンサーの作製とニッケルイオンの高感度定量分析, 日本分析化学会第80回分析化学討論会, 2020年5月.
75.	三宅晃嗣, 岩崎颯太, 岡部浩隆, 松田直樹, 水口仁志, 髙栁俊夫 : 金ナノ粒子の分散安定性評価におけるキャピラリー電気泳動法の活用, 日本分析化学会第80回分析化学討論会, 2020年5月.
76.	朝桐佑記, 小林美咲, 眞野翼, 谷渕諒一, 酒巻武史, 吉川直人, 木島龍朗, 髙栁俊夫, 水口仁志 : トラックエッチ膜フィルター電極を用いる積層型アプタセンサーの開発, 日本分析化学会第80回分析化学討論会, 2020年5月.
77.	橋本陸央, 桑原知彦, 松本健嗣, 堀田弘樹, 髙栁俊夫, 水口仁志 : トラックエッチ膜フィルター二重電極検出器を備えたHPLCによるフェノール系化合物の分離検出, 日本分析化学会第80回分析化学討論会, 2020年5月.
78.	峯大典, 水口仁志, 髙栁俊夫 : キャピラリー電気泳動/動的前端分析によるβ-D-ガラクトシダーゼの基質競合解析, 日本分析化学会第80回分析化学討論会, 2020年5月.
79.	峯大典, 水口仁志, 髙栁俊夫 : 動的インキャピラリ―反応によるアルカリフォスファターゼの阻害測定, 2019年日本化学会中国四国支部大会, 2019年11月.
80.	岩崎颯太, 森田耕太郎, 平山直紀, 水口仁志, 髙栁俊夫 : キャピラリー電気泳動法による電気炉加熱分解法により合成されたCNDの物性評価, 2019年日本化学会中国四国支部大会, 2019年11月.
81.	谷上裕紀, 田上拓磨, 荒川幸弘, 水口仁志, 髙栁俊夫 : 圧力支援キャピラリー電気泳動法による易分解性フラビン誘導体の酸解離定数の決定, 2019年日本化学会中国四国支部大会, 2019年11月.
82.	西森大地, 桑原知彦, 竹内政樹, 飯山真充, 髙栁俊夫, 水口仁志 : トラックエッチ膜フィルター電極を用いるキャピラリーHPLC-電量検出法の開発, 2019年日本化学会中国四国支部大会, 2019年11月.
83.	松本直也, 峯大典, 水口仁志, 髙栁俊夫 : 圧力支援キャピラリー電気泳動/動的前端分析によるカルボキシルエステラーゼの酵素反応解析, 第39回キャピラリー電気泳動シンポジウム, 2019年11月.
84.	峯大典, 水口仁志, 髙栁俊夫 : キャピラリー電気泳動/動的前端分析によるβ-D-ガラクトシダーゼの酵素反応解析, 第39回キャピラリー電気泳動シンポジウム, 2019年11月.
85.	髙栁俊夫, 峯大典 : キャピラリー電気泳動/ダイナミックフロンタルアナリシスによる酵素反応の解析, 第39回キャピラリー電気泳動シンポジウム, 2019年11月.
86.	Nishimori Daichi, Tomohiko Kuwabara, Masaki Takeuchi, Iiyama Masamitsu, Toshio Takayanagi and Hitoshi Mizuguchi : HPLC-coulometric detection using track etched microporous membrane electrodes and its aplication to the determination of catecholamines, International JAFIA 35th Anniversary Symposium with Profs. Christian and Dasgupta & the 56th Meeting of the Japanese Association for Flow Injection Analysis, Oct. 2019.
87.	西森大地, 桑原知彦, 竹内政樹, 飯山真充, 髙栁俊夫, 水口仁志 : トラックエッチ膜フィルター電極を用いるHPLC-電気化学検出によるカテコールアミンのクーロメトリー検出, 日本分析化学会第68年会, 2019年9月.
88.	水口仁志, 谷口友亮, 梅田玄野, (名) Suherman, 髙栁俊夫, 森田金市 : 迅速な前濃縮法と携帯型比色計との組み合わせによる微量ニッケルイオンの現場分析, 日本分析化学会第68年会, 2019年9月.
89.	谷上裕紀, 田上拓磨, 荒川幸弘, 水口仁志, 髙栁俊夫 : キャピラリーゾーン電気泳動法による易分解性フラビン誘導体の酸解離平衡の解析, 第26回クロマトグラフィーシンポジウム, 2019年6月.
90.	岩崎颯太, 矢部駿, 森田耕太郎, 平山直紀, 水口仁志, 髙栁俊夫 : キャピラリー電気泳動法によるグルタミン酸から合成した水溶性カーボンナノドットの親水性/疎水性の評価, 第26回クロマトグラフィーシンポジウム, 2019年6月.
91.	水口仁志, 西森大地, 桑原知彦, 竹内政樹, 飯山真充, 髙栁俊夫 : トラックエッチ膜フィルター電極を搭載した低容積フロー電解セルを用いるHPLC-電気化学検出, 第26回クロマトグラフィーシンポジウム, 2019年6月.
92.	桑原知彦, 西森大地, 飯山真充, 竹内政樹, 髙栁俊夫, 水口仁志 : トラックエッチ膜フィルター電極を用いるHPLC多電位検出システムにおけるポリフェノール類の検出挙動, 第79回分析化学討論会, 2019年5月.
93.	山田洋平, 髙栁俊夫, 村井啓一郎, 薮谷智規 : 水酸化ランタン固相と過酸化水素溶離系における抽出金属イオン種の選択性評価, 第79回分析化学討論会, 2019年5月.
94.	岩崎颯太, 矢部駿, 森田耕太郎, 平山直紀, 水口仁志, 髙栁俊夫 : キャピラリー電気泳動法によるグルタミン酸から合成した水溶性カーボンナノドットのキャラクタリゼーション, 第79回分析化学討論会, 2019年5月.
95.	谷上裕紀, 田上拓磨, 荒川幸弘, 水口仁志, 髙栁俊夫 : キャピラリーゾーン電気泳動法を用いた易分解性フラビン誘導体の酸解離平衡解析, 第79回分析化学討論会, 2019年5月.
96.	髙栁俊夫, 別役優太, 水田悠斗, 水口仁志 : ポリスチレンスルホン酸イオンを分散剤として用いるグラフェンのキャピラリー電気泳動, 第38回キャピラリー電気泳動シンポジウム, 2018年12月.
97.	西森大地, 竹内政樹, 飯山真充, 髙栁俊夫, 水口仁志 : トラックエッチ膜フィルター電極を用いるHPLC-電気化学検出によるカテコールアミンの分離検出, 第55回フローインジェクション分析講演会, 2018年11月.
98.	髙栁俊夫, 峯大典, 水口仁志 : キャピラリー電気泳動/動的前端分析による酵素反応の速度論解析, 第29回クロマトグラフィー科学会議, 2018年11月.
99.	薮谷智規, 岸邊慎吾, 上村美貴, 野添宏介, 山田洋平, 髙栁俊夫 : オンサイト試料処理/固相抽出/誘導結合プラズマ質量分析法による天然水中の銅のスペシエーション法の開発, 第6回メタロミクス研究フォーラム, 2018年11月.
100.	山田洋平, 髙栁俊夫, 薮谷智規 : 水酸化ランタンへのMo(VI), V(V), W(VI)の吸着挙動とH2O2による溶離挙動の解析, 日本分析化学会第67年会, 2018年9月.
101.	岡田浩輝, 渕脇雄介, 水口仁志, 髙栁俊夫 : マイクロ流体ペーパー分析デバイスを用いたジチゾンの変色距離の比較によるZn2+の半定量, 日本分析化学会第67年会, 2018年9月.
102.	別役優太, 矢部駿, 森田耕太郎, 平山直紀, 水口仁志, 髙栁俊夫 : マイクロ波照射法で合成した水溶性カーボンナノドットのキャピラリー電気泳動法によるキャラクタリゼーション, 第78回分析化学討論会, 2018年5月.
103.	峯大典, 水口仁志, 髙栁俊夫 : インキャピラリー反応による酵素反応の速度論反応解析―アルカリフォスファターゼによるリン酸エステルの加水分解反応―, 第78回分析化学討論会, 2018年5月.
104.	西森大地, 竹内政樹, 飯山真充, 髙栁俊夫, 水口仁志 : トラックエッチ膜フィルター電極を検出器とする高速液体クロマトグラフィーシステムの開発, 第78回分析化学討論会, 2018年5月.
105.	西森大地, 竹内政樹, 髙栁俊夫, 水口仁志 : HPLC電気化学検出におけるトラックエッチ膜フィルター電極の適用について, 第54回フローインジェクション分析講演会, 2017年11月.
106.	髙栁俊夫 : CZEの分離機能を活用する反応活性物質の平衡反応解析, 第37回キャピラリー電気泳動シンポジウム, 2017年11月.
107.	水口仁志, 吉川直人, 飯山真充, 木島龍朗, 髙栁俊夫 : トラックエッチ膜フィルターを鋳型とする多孔性電極の作製と複数種同時定量用デバイスへの試み, 第63回ポーラログラフィーおよび電気分析化学討論会, 2017年11月.
108.	伊藤大地, 水口仁志, 髙栁俊夫 : キャピラリーゾーン電気泳動法による酸化分解性プロトカテク酸の酸解離平衡反応の解析, 第28回クロマトグラフィー科学会議, 2017年11月.
109.	伊藤大地, 水口仁志, 髙栁俊夫 : キャピラリーゾーン電気泳動法を用いた易分解性プロトカテク酸の酸解離定数の決定, 2017年日本化学会中国四国支部大会, 2017年11月.
110.	岡田浩輝, 水口仁志, 髙栁俊夫 : マイクロ流体ペーパー分析デバイスを用いたEDTAによるZn2+の簡易分析, 2017年日本化学会中国四国支部大会, 2017年11月.
111.	山田洋平, 椋田千景, 村井啓一郎, 髙栁俊夫, 薮谷智規 : 過酸化水素添加時の水酸化ランタン担体からのMo(Ⅵ), V(Ⅴ), W(Ⅵ)の溶離挙動, 日本分析化学会第66年会, 2017年9月.
112.	髙栁俊夫, 池内伽奈子, 別役優太, 水口仁志 : SDSを用いたカーボンナノチューブのミセル動電クロマトグラフィー, 日本分析化学会第66年会, 2017年9月.
113.	髙栁俊夫, 磯田昌志, 伊藤大地, 水口仁志 : キャピラリーゾーン電気泳動法によるヒドロクロロチアジドとその分解生成物の酸解離平衡の解析, 日本分析化学会第66年会, 2017年9月.
114.	別役優太, 水口仁志, 髙栁俊夫 : ミセル動電クロマトグラフィーの容量比からみたグラフェンのミセル分配, 日本分析化学会第66年会, 2017年9月.
115.	石田亮太, 河野泰志, 橘忠彦, 本田知己, 木島龍朗, 髙栁俊夫, 水口仁志 : ナイロンナノファイバーフィルターを用いる超微量ニッケル及び銅の迅速な濃縮と比色分析, 日本分析化学会第66年会, 2017年9月.
116.	髙栁俊夫, 別役優太, 水口仁志 : ポリエチレングリコールを添加したミセル動電クロマトグラフィーにおけるグラフェンの保持挙動とシグナル形状の変化, 第27回クロマトグラフィー科学会議, 2016年11月.
117.	髙栁俊夫 : グリーンケミストリーと分析化学, 平成28年度化学教育研究会, 2016年11月.
118.	別役優太, 水口仁志, 髙栁俊夫 : PEGを添加したミセル動電クロマトグラフィーにおけるグラフェン懸濁液の電気泳動, 第36回キャピラリー電気泳動シンポジウム, 2016年11月.
119.	岡田英理子, 髙栁俊夫 : キャピラリー電気泳動法を用いたエステラーゼによる酢酸p-ニトロフェニルの加水分解反応速度の解析, 第36回キャピラリー電気泳動シンポジウム, 2016年11月.
120.	伊藤大地, 髙栁俊夫 : キャピラリーゾーン電気泳動法を用いたブプロピオンの分解反応の追跡と分解条件下での酸解離平衡解析, 第36回キャピラリー電気泳動シンポジウム, 2016年11月.
121.	水口仁志, 佐々木景子, 市瀬博一, 清野翔太, 櫻井淳, 飯山真充, 木島龍朗, 立花和宏, 仁科辰夫, 髙栁俊夫, 志田惇一 : トラックエチ膜フィルター電極システムを用いる乳酸とグルコースの同時定量, 第53回フローインジェクション分析講演会, 2016年11月.
122.	吉川直人, 飯島真充, 木島龍朗, 髙栁俊夫, 水口仁志 : アルカンチオール修飾型多孔質金電極の作製とコレステロール検出, 日本化学会中国四国支部大会, 2016年11月.
123.	吉川直人, 飯島真充, 木島龍朗, 髙栁俊夫, 水口仁志 : トラックエッチ膜を鋳型とする多孔質電極を用いるコレステロールの迅速検出, 日本分析化学会第65年会, 2016年9月.
124.	山田洋平, 椋田千景, 村井啓一郎, 髙栁俊夫, 薮谷智規 : 過酸化水素を溶出液とする水酸化ランタン共沈殿からのオキソ酸金属イオンの回収, 日本分析化学会第65年会, 2016年9月.
125.	橋本直哉, 髙栁俊夫, 安澤幹人, 薮谷智規 : イオンクロマトグラフィーによるフッ化水素酸とヘキサフルオロケイ酸の同時定量, 第76回分析化学討論会, 2016年5月.
126.	岡田英理子, 髙栁俊夫 : キャピラリー電気泳動法を用いたエステラーゼの加水分解反応の速度論解析, 第76回分析化学討論会, 2016年5月.
127.	伊藤大地, 髙栁俊夫 : キャピラリー電気泳動法による分解反応下でのブプロピオンの酸解離反応解析, 第76回分析化学討論会, 2016年5月.
128.	小林拓真, 髙栁俊夫, Geoffery Waterhouse, 薮谷智規 : インバースオパール構造炭素を用いた新規な炭素電極の作製, 第76回分析化学討論会, 2016年5月.
129.	別役優太, 倉科昌, 髙栁俊夫 : グラフェン懸濁液のミセル動電クロマトグラフィーにおけるポリエチレングリコールの添加効果, 第76回分析化学討論会, 2016年5月.
130.	髙栁俊夫 : キャピラリーゾーン電気泳動分離を活用する易分解性物質の反応物性解析, 第26回クロマトグラフィー科学会議, 2015年11月.
131.	島上夏美, 薮谷智規, 髙栁俊夫 : キャピラリーゾーン電気泳動法によるヘキサメチレンテトラミンの酸解離反応解析, 第35回キャピラリー電気泳動シンポジウム, 2015年11月.
132.	斉傲晨, 薮谷智規, 髙栁俊夫, 平野朋広 : ポリペルオキシド修飾シリカゲルの合成とその評価, 第5回CSJ化学フェスタ, 2015年10月.
133.	岸邊慎吾, 上村美貴, 髙栁俊夫, 薮谷智規 : 固相抽出/誘導結合プラズマ質量分析法を用いた海水中Cu(I/II)の酸化数別定量法の開発, 日本海水学会第66年会, 2015年6月.
134.	薮谷智規, 西前真治, 磯部能史, 山田洋平, 髙栁俊夫, 平野朋広 : カルボキシル基導入高分岐ポリマー及び活性炭を用いるヘキサメチレンテトラミンの除去, 第75回分析化学討論会, 2015年5月.
135.	島上夏美, 薮谷智規, 髙栁俊夫 : キャピラリーゾーン電気泳動法を用いたヘキサメチレンテトラミンの酸解離反応解析, 第75回分析化学討論会, 2015年5月.
136.	Toshio Takayanagi : Equilibrium Analysis by Capillary Zone Electrophoresis - Its Characteristics and Advantages, 1st Asian Symposium on Analytical Sciences, Sep. 2014.
137.	鈴田崇仁, 山田洋平, 薮谷智規, 髙栁俊夫, 鈴木良尚 : トラックエッチドメンブレンフィルター孔でのリゾチーム結晶成長, 日本分析化学会第63年会, 2014年9月.
138.	小西雅志, 薮谷智規, 髙栁俊夫 : セルロース上へのMo(VI)，W(VI)，V(V) を含む多種金属イオンの吸着挙動, 日本分析化学会第63年会, 2014年9月.
139.	山田洋平, 鈴田崇仁, 薮谷智規, 鈴木良尚, 永瀬丈嗣, 保田英洋, 髙栁俊夫 : フェリチンの結晶を鋳型とした規則構造体の合成, 日本分析化学会第63年会, 2014年9月.
140.	島上夏美, 薮谷智規, 髙栁俊夫 : キャピラリーゾーン電気泳動法を用いた光分解性ハロペリドールの酸解離反応解析, 日本分析化学会第63年会, 2014年9月.
141.	髙栁俊夫 : キャピラリー電気泳動法によるポリエーテル系非イオン界面活性剤ミセルへの結合反応解析とイオン種結合の選択性, 日本分析化学会第63年会, 2014年9月.
142.	平林和久, 花岡健二郎, 髙栁俊夫, 長野哲雄, 浦野泰照 : Si置換フルオレセインの化学平衡の解析とプローブ開発への応用, 日本薬学会第134年会, 2014年3月.
143.	細野晃弘, 髙栁俊夫, 高橋透 : フタレイン系色素エステルのキャピラリー内加水分解反応挙動とzone-passing モードキャピラリー電気泳動反応器によるその反応速度解析, 日本化学会第94春季年会, 2014年3月.
144.	金田隆, 金地啓介, 武安伸幸, 髙栁俊夫 : 二波長検出による多重標識タンパク質の等速電気泳動分離, 第33回キャピラリー電気泳動シンポジウム, 41-42, 2013年11月.
145.	髙栁俊夫, 小倉絹代, 薮谷智規 : ジピクリルアミネートイオンのK+，Cs+との選択的沈殿に関する考察-キャピラリーゾーン電気泳動法による水溶液内イオン会合反応の解析から, 第33回キャピラリー電気泳動シンポジウム, 91-92, 2013年11月.
146.	髙栁俊夫, 森本雅紀, 薮谷智規 : ミセル動電クロマトグラフィーによるグラフェンと酸化グラフェンの分離検出, 第24回クロマトグラフィー科学会議, 129-130, 2013年11月.
147.	鈴田崇仁, 山田洋平, 薮谷智規, 髙栁俊夫, 鈴木良尚 : リゾチーム単結晶への金属酸化物前駆体の含浸, 第3回CSJ化学フェスタ2013, 2013年10月.
148.	小西雅志, 隅英彦, 明槻伸介, 薮谷智規, 髙栁俊夫 : 過酸化水素を溶離液とするイミノ二酢酸型キレート樹脂からのV,Mo,Wの回収, 第3回CSJ化学フェスタ2013, 2013年10月.
149.	渡邊敏夫, 中野祥孝, 山田洋平, 薮谷智規, 安澤幹人, 髙栁俊夫 : グルコースオキシダーゼの電解析出に対する電極表面の疎水性効果, 日本分析化学会第62年会, 2013年9月.
150.	西前真治, 岸田千紘, 薮谷智規, 髙栁俊夫, 平野朋広, 右手浩一 : 末端官能性高分岐ポリマー電解質を用いたポリイオンコンプレックスの形成に基づく溶存有機物の回収, 日本分析化学会第62年会, 2013年9月.
151.	平林和久, 土岐裕子, 髙栁俊夫, 長野哲雄, 花岡健二郎 : ケイ素置換フルオレセインの化学平衡式に基づく赤色蛍光プローブの精密設計, 日本分析化学会第62年会, 2013年9月.
152.	髙栁俊夫 : 電気泳動移動度測定による溶液内反応解析-キャピラリー電気泳動法だからこそできること-, 日本分析化学会第62年会電気泳動分析研究懇談会, 2013年9月.
153.	山田洋平, 鈴田崇仁, 薮谷智規, Metson James, Williams David, 永瀬丈嗣, 髙栁俊夫 : フェリチン結晶を鋳型とした多孔質材料創成の試み, 日本分析化学会第62年会, 2013年9月.
154.	猪井勇志, 木村あゆみ, 薮谷智規, 髙栁俊夫 : 2, 3-ジアミノナフタレン-塩酸ヒドロキシルアミンとの反応に基づくクロム(VI)及びセレンのHPLC-蛍光同時定量, 日本分析化学会第62年会, 2013年9月.
155.	木村あゆみ, 髙栁俊夫, 薮谷智規 : Speciation anaylsis of Slenium (IV, VI) by flow injection analysis using 2,3-diaminonaphthalene, 第19回中国四国支部分析化学若手セミナー, 2013年9月.
156.	小西雅志, 隅英彦, 明槻伸介, 薮谷智規, 髙栁俊夫 : Recovery of V, Mo and W on iminodiacetate chelating resin by hydrogen peroxide as eluant, 第19回中国四国支部分析化学若手セミナー, 2013年9月.
157.	鈴田崇仁, 山田洋平, 薮谷智規, 髙栁俊夫, 鈴木良尚 : Penetration of precursors of metallic oxide into lysozyme crystals, 第19回中国四国支部分析化学若手セミナー, 2013年9月.
158.	薮谷智規, 上村美貴, 椋田千景, 山田洋平, 髙栁俊夫 : 海水中一価および二価銅イオンの形態別定量に向けた現場固相抽出法の開発, 第73回分析化学討論会, 2013年5月.
159.	渡邊敏夫, 山田洋平, 薮谷智規, 安澤幹人, 髙栁俊夫, 本仲純子, 櫻庭春彦 : 酵素の電解析出に対するナノ粒子の効果およびそのバイオ電池作製への適用, 第58回ポーラログラフィーおよび電気分析化学討論会, 2012年11月.
160.	猪井勇志, 椋田千景, 木下峻輔, 薮谷智規, 髙栁俊夫 : 2,3-ジアミノナフタレンとの反応を用いたクロム(VI)のHPLC-蛍光定量法の開発, 2012年日本化学会日日本大会, 54, 2012年11月.
161.	西前真治, 磯部能史, 薮谷智規, 髙栁俊夫, 平野朋広, 右手浩一 : 末端官能性高分岐ポリマーを用いたポリイオンコンプレックスの合成とその特性評価, 2012年日本化学会西日本大会, 54, 2012年11月.
162.	髙栁俊夫 : 電気泳動移動度測定による結合特性解析からみたポリエーテル系非イオン界面活性剤ミセルのイオン交換能, 第28回日本イオン交換研究発表会, 2012年10月.
163.	西前真治, 岸田千紘, 磯部能史, 薮谷智規, 髙栁俊夫, 平野朋広, 右手浩一 : 開始剤組み込みラジカル重合法を用いた末端官能性高分岐ポリマー電解質の合成とその化学的特性評価, 第2回CSJ化学フェスタ2012, 2012年10月.
164.	猪井勇志, 椋田千景, 木下峻輔, 薮谷智規, 髙栁俊夫 : 2,3-ジアミノナフタリンを用いたクロム1(VI)の蛍光検出―液体クロマトグラフ定量法の開発, 第2回CSJ化学フェスタ2012, 2012年10月.
165.	渡邊敏夫, 山田洋平, 薮谷智規, 安澤幹人, 髙栁俊夫, 本仲純子, 櫻庭春彦 : 電解析出法による耐熱性酵素CotAの固定化とそれに及ぼすナノ材料の効果, 日本分析化学会第61年会, 280, 2012年9月.
166.	山田洋平, 外山翔太, James METSON, David WILLIAMS, Geoff WATERHOUSE, 鈴木良尚, 薮谷智規, 髙栁俊夫 : タンパク質結晶を鋳型とした規則性多孔質材料の作製, 日本分析化学会第61年会, 165, 2012年9月.
167.	椋田千景, 谷昂亮, THUY THI XUAN LE, 薮谷智規, 髙栁俊夫 : 過酸化水素とオゾンによる金属水酸化物共沈担体からの金属イオン溶出, 日本分析化学会第61年会, 77, 2012年9月.
168.	髙栁俊夫 : グリーン分析化学を実現するフローインジェクション分析, 日本分析化学会第61年会, 92, 2012年9月.
169.	西前真治, 岸田千紘, 磯部能史, 薮谷智規, 髙栁俊夫, 平野朋広, 右手浩一 : 開始剤組み込みラジカル重合法を用いた末端イオン性高分岐ポリマーの合成とその特性評価, 第18回中国四国支部分析化学若手セミナー, 2012年8月.
170.	猪井勇志, 椋田千景, 木下峻輔, 薮谷智規, 髙栁俊夫 : 2, 3–ジアミノナフタレンを用いるクロム(VI)の蛍光検出とその反応メカニズムの解析, 第18回中国四国支部分析化学若手セミナー, 2012年8月.
171.	Thuy Thi Xuan Le, 薮谷智規, 髙栁俊夫, 安澤幹人 : γ-ポリグルタミン酸を用いる活性炭微粒子の浮遊回収, 第72回分析化学討論会, 102, 2012年5月.
172.	東谷直樹, 髙栁俊夫, 金田隆 : キャピラリー電気泳動法によるテトラフェニルボレート誘導体と一価陽イオンの水溶液内イオン会合解析, 第72回分析化学討論会, 2012年5月.
173.	金地啓介, 髙栁俊夫, 金田隆 : 二波長検出キャピラリー電気泳動法によるタンパク質の標識効率の評価, 第72回分析化学討論会, 2012年5月.
174.	渡邊敏夫, 山田洋平, 薮谷智規, 安澤幹人, 髙栁俊夫, 本仲純子, 櫻庭春彦 : 耐熱性酵素の電気化学的析出条件の検討およびそのバイオ電池作製への適用, 電気化学会第79回大会, 2012年3月.
175.	椋田千景, 隅英彦, 中村崇聖, 薮谷智規, 髙栁俊夫 : オゾン水を溶離液とする共沈担体からの溶離挙動の解析, 日本海水学会若手会第3回学生研究発表会, P14, 2012年3月.
176.	髙栁俊夫 : 化学的な分離分析法を活用する物性分析, 徳島大学工業会 T&E会(四国), 2012年1月.
177.	髙栁俊夫 : イオン種の電気泳動移動度測定に基づく迅速な溶液内平衡物性の解析, 第16回徳島地区分析技術セミナー, 2012年1月.
178.	Eakkasit PUNRAT, Toshio Takayanagi, Suchada CHUANUWATANAKUL, Takashi KANETA, Shoji MOTOMIZU and Orawon CHAILAPAKUL : Determination of Arsenic(III) by Sequential Injection-Anodic Stripping Voltammetry Using Thin Film-Modified Screen-Printed Carbon Electrode, 第49 回フローインジェクション分析講演会, Dec. 2011.
179.	髙栁俊夫 : キャピラリーゾーン電気泳動法による速度論反応共存下での迅速な平衡反応の解析, 第31回キャピラリー電気泳動シンポジウム, 2011年11月.
180.	髙栁俊夫 : 溶液内反応の平衡論研究におけるキャピラリーゾーン電気泳動法の活用, 第30回キャピラリー電気泳動シンポジウム, 2010年11月.
181.	髙栁俊夫 : キャピラリーゾーン電気泳動法を用いる溶液内平衡解析, 2010年日本化学会西日本大会, 2010年11月.
182.	髙栁俊夫 : グリーンケミストリーを指向する水系分析化学とその設計, 周南地区講演会, 2009年12月.
183.	髙栁俊夫 : 化学系の教育-学部教育と大学院教育, 第3回理学系大学教育に関する研究フォーラム, 2009年12月.
184.	髙栁俊夫 : 環境負荷低減を指向する水系分析化学:キャピラリー電気泳動法の活用, 2005年日本化学会西日本大会, 2005年10月.
185.	髙栁俊夫 : キャピラリー電気泳動法による水溶液内平衡反応解析と高機能分離分析, 15回クロマトグラフィー科学会議, 2004年11月.
186.	髙栁俊夫 : 化学発光検出による大気中オゾンの高感度モニタリング法の開発とテキサステック大学での研究生活, 岡山地区講演会, 2004年2月.
187.	髙栁俊夫 : クロモトロープ酸を用いるオゾンの化学発光検出と環境分析への応用, 2003年日本化学会西日本大会, 2003年10月.
188.	髙栁俊夫 : 非イオン界面活性剤を用いるイオン性物質のキャピラリー電気泳動分離, 2003年日本化学会西日本大会, 2003年10月.
189.	髙栁俊夫 : キャピラリー電気泳動法による溶液内分子間相互作用の解析, 第43回分子科学若手の会夏の学校, 2003年8月.
190.	髙栁俊夫 : 溶液内平衡反応の解析装置としての高速液体クロマトグラフィーの活用, 日本化学会中国四国支部・九州支部合同大会, 2001年10月.

その他・研究会:

1.	Toshio Takayanagi, Kenichiro Todoroki, Takuya Kubo and Ikuo Ueta : Guest Editorial: Frontiers of Separation Analysis, Analytical Sciences, Vol.40, No.6, 1215, Jun. 2024. (出版サイトへのリンク) ● Publication site (DOI): 10.1007/s44211-024-00563-1 (文献検索サイトへのリンク) ● Search Scopus @ Elsevier (DOI): 10.1007/s44211-024-00563-1 (DOI: 10.1007/s44211-024-00563-1)
2.	猪井勇志, 木村あゆみ, 薮谷智規, 髙栁俊夫 : 2,3-ジアミノナフタレン誘導体化/HPLC-蛍光検出を用いるCr(VI)及びSe(IV,VI)スペシエーション法の開発, 第18回徳島地区分析技術セミナー, 12-13, 2013年12月.
3.	髙栁俊夫 : 界面活性剤ミセルを疑似有機溶媒として用いる水系分離分析, 第13回エンジニアリングフェスティバル, 12, 2013年9月.
4.	Toshio Takayanagi : FIA Bibliography (51), Journal of Flow Injection Analysis, Vol.26, No.1, 64-78, Jun. 2009.
5.	Toshio Takayanagi : FIA Bibliography (50), Journal of Flow Injection Analysis, Vol.25, No.2, 196-208, Dec. 2008.
6.	Toshio Takayanagi : FIA Bibliography (49), Journal of Flow Injection Analysis, Vol.25, No.1, 91-104, Jun. 2008.
7.	Toshio Takayanagi : FIA Bibliography (48), Journal of Flow Injection Analysis, Vol.24, No.2, 141-156, Dec. 2007.
8.	Toshio Takayanagi : FIA Bibliography (47), Journal of Flow Injection Analysis, Vol.24, No.1, 29-44, Jun. 2007.
9.	Toshio Takayanagi : FIA Bibliography (46), Journal of Flow Injection Analysis, Vol.23, No.2, 138-153, Dec. 2006.

報告書:

1.	髙栁俊夫 : Analytical Sciences誌の国際化が進んでいます, ぶんせき, Vol.2024, No.8, 285, 2024年8月.
2.	植野美彦, 関陽介, 内海千種, 岩佐武, 髙橋章, 安井敏之, 川人伸次, 尾崎和美, 藤野裕道, 髙栁俊夫, 服部武文, 齊藤隆仁, 上岡麻衣子 : 令和5年度徳島大学高等教育研究センターアドミッション部門報告書, 令和5年度徳島大学高等教育研究センターアドミッション部門報告書, 2024年3月.
3.	髙栁俊夫 : 第20回を迎えた中国四国支部分析化学若手セミナー, ぶんせき, Vol.2015, No.5, 212, 2015年5月.
4.	髙栁俊夫 : 第13回中国四国支部分析化学若手セミナー, ぶんせき, Vol.2007, No.11, 615-616, 2007年11月.
5.	髙栁俊夫 : 第21回キャピラリー電気泳動シンポジウム, ぶんせき, Vol.2002, No.3, 140-141, 2002年3月.
6.	髙栁俊夫 : 分析21世紀基金「倉敷会議」報告, ぶんせき, Vol.2001, No.1, 44-45, 2001年1月.
7.	髙栁俊夫 : 第49年会付設若手シンポジウム報告, ぶんせき, Vol.2001, No.1, 43-44, 2001年1月.

科学研究費補助金 (KAKEN Grants Database @ NII.ac.jp)

マルチ陽極・陰極ペア検出HPLCを用いる抗酸化性食品の状態診断法の開発 (研究課題/領域番号: 24K15324 )
ダイナミックフロンタルアナリシス法による溶液内速度論反応解析の展開 (研究課題/領域番号: 24K08464 )
有害化学物質を識別する陽極・陰極ペア検出HPLCの創製－食の安全を確保するー (研究課題/領域番号: 21K19869 )
キャピラリー電気泳動／ダイナミックフロンタルアナリシス法の開発 (研究課題/領域番号: 20K05568 )
グラフェンの水溶液内分散とミセル動電クロマトグラフィーによる化学的評価法の開発 (研究課題/領域番号: 17K05903 )
分離分析を活用する副反応進行下での平衡反応解析法の確立 (研究課題/領域番号: 26410154 )
ポリエーテルによる包摂とイオン会合との相乗効果に基づく水系分離分析法の開発 (研究課題/領域番号: 22550075 )
非イオン界面活性剤ミセルを媒体とするイオン会合抽出と分離分析 (研究課題/領域番号: 19550090 )
水溶液内イオン会合解析に基づく高選択的イオン会合試薬の設計・合成と分析化学的研究 (研究課題/領域番号: 16350044 )
新規キトサン誘導体固定相の合成と新しいクロマトグラフ法の開発 (研究課題/領域番号: 15750068 )
金属内包フラーレンの固体・薄膜・ナノ物性 (研究課題/領域番号: 15350089 )
イオン周囲のミクロ環境制御による高機能イオン会合試薬の設計・合成と分析化学的応用 (研究課題/領域番号: 13440220 )
イオン会合ミセル分配-キャピラリー電気泳動法に適合する高感度検出試薬の開発 (研究課題/領域番号: 12740409 )
二酸化炭素の海水への溶存状態精密解析とオンサイト計測システム構築 (研究課題/領域番号: 10558084 )
水溶液内イオン会合/キャピラリー電気泳動の高機能化のための多点相互作用試薬の開発 (研究課題/領域番号: 09740555 )
キャピラリー電気泳動法による水溶液内イオン会合挙動の解明 (研究課題/領域番号: 08740577 )
二酸化炭素の精密測定装置の試作と海水への溶存状態解明 (研究課題/領域番号: 08558059 )
研究者番号（50263554）による検索

教授 : 髙栁俊夫

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科学研究費補助金 (KAKEN Grants Database @ NII.ac.jp)

教授 : 髙栁 俊夫

研究活動

個人のホームページ

専門分野

研究テーマ

著書・論文

著書:

学術論文(審査論文):

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国際会議:

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科学研究費補助金 (KAKEN Grants Database @ NII.ac.jp)

教授 : 髙栁俊夫