Tokushima University / Educator and Researcher Directory --- Takizawa, Hiromitsu

Field of Study

○	Medicine

Subject of Study

○

Book / Paper

Book:

1.	Akira Tangoku, Takahiro Yoshida, Hiroaki Toba, Hirokazu Takechi, Kazumasa Okumura, Takeshi Nishino, Seiya Inoue, Misako Nakagawa, 森本雅美, Toru Sawada, 青山万理子, 宮本直輝, 西岡康平, 藤本啓介 and Hiromitsu Takizawa : CT lymphography for superficial esophageal cancer, 2017.

Academic Paper (Judged Full Paper):

1.	Daisuke Matsumoto, Hiroaki Toba, Koichiro Kenzaki, Shoji Sakiyama, Shin-ichi Sakamoto, Mika Takashima, Naoya Kawakita and Hiromitsu Takizawa : Lung regeneration with rat fetal lung implantation and promotion of alveolar stem cell differentiation by corticosteroids, Regenerative Therapy, Vol.24, 426-433, 2023. (Summary) The lung is a difficult organ to regenerate, and the development of functional lungs has still not been achieved. In this study, we investigated lung regeneration using a rat fetal lung tissue-implanted model. This study aimed to evaluate the functioning of the implanted fetal lung tissue and investigate the graft differentiation and maturation mechanism, focusing on alveolar stem cells. Fetal lung tissue fragments were obtained from Lewis rats on day 17 and implanted into adult lungs. Animals were divided into the following three groups: group 1, injection into the adult left lung parenchyma; group 2, injection with post-caval lobectomy; and group 3, injection with post-caval lobectomy and corticosteroid administration. Computed tomography was performed on weeks 1, 2, 4, and 8. The presence of alveolar pore, CD31 expression, and bipotential progenitor cell (podoplanin+/surfactant protein C+) localization were histologically evaluated. MiRNA expression was comprehensively compared among the three groups. The grafts comprised type I and type II alveolar cells connected to the recipient lungs with alveolar pores and capillary networks in the interstitial tissue. The alveolar space was the largest and the computed tomography value was the lowest in the grafts of the corticosteroid-administered group. The number of bipotential progenitor cells was the lowest in the corticosteroid administration group on day 7. Moreover, microRNA-487-3p, 374-5p, and 20b-5p expression was changed by more than 2-fold between the post-caval lobectomy and corticosteroid administration groups. Implanted fetal lung tissues established airway and capillary communication with the recipient lungs, and corticosteroids accelerated their maturation by promoting the differentiation of progenitor cells. The study findings provide new insights into lung regeneration research. (Tokushima University Institutional Repository) ● Metadata: 119055 (Link to Publication Site) ● Publication site (DOI): 10.1016/j.reth.2023.09.006 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 37744680 ● Search Scopus @ Elsevier (PMID): 37744680 ● Search Scopus @ Elsevier (DOI): 10.1016/j.reth.2023.09.006 (Tokushima University Institutional Repository: 119055, DOI: 10.1016/j.reth.2023.09.006, PubMed: 37744680)
2.	Linwan Zhang, Kazuya Kondo, Takae Bando, Naoya Kawakita, Hiroaki Toba, Yoshie Imai and Hiromitsu Takizawa : Assessment of dyspnea, ADL, and QOL in the perioperative period in lung cancer patients treated with minimally invasive surgery, The Journal of Medical Investigation : JMI, Vol.70, No.3.4, 388-402, 2023. (Summary) Patients with lung cancer generally undergo minimally invasive surgery, such as video-assisted thoracoscopic surgery (VATS). This study examined the changes in health conditions and symptoms of patients with lung cancer using the European Organization for Research and Treatment of Cancer-Quality of Life Questionnaire (EORTC QLQ) C-30 questionnaires after surgery. This was a longitudinal descriptive study. One hundred and three patients with lung cancer who underwent lung resection at Tokushima University Hospital between 2012 and 2021 were eligible. They completed EORTC QLQ-C30, QLQ-LC13, the Cancer Dyspnea scale (CDS), and pulmonary-ADL (P-ADL) before and 1, 3, and 6 months after surgery. Regarding functional scale scores, impairments in physical and role functions persisted for 6 months after surgery. In symptom scale scores, fatigue, pain, dyspnea, and appetite loss continued for 6 months after surgery. In CDS, sense of effort, discomfort, and total dyspnea scale scores were elevated for 6 months after surgery. In P-ADL, most ADL were impaired 1 month after surgery, but recovered by 3 months. The dyspnea index of ADL was lower for 6 months after surgery. Impairments in health conditions and symptoms persisted for 6 months after surgery despite its minimally invasive nature. J. Med. Invest. 70 : 388-402, August, 2023. (Keyword) Humans / Lung Neoplasms / Quality of Life / Activities of Daily Living / Dyspnea / Perioperative Period / Minimally Invasive Surgical Procedures / Surveys and Questionnaires (Link to Publication Site) ● Publication site (DOI): 10.2152/jmi.70.388 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 37940523 ● Search Scopus @ Elsevier (PMID): 37940523 ● Search Scopus @ Elsevier (DOI): 10.2152/jmi.70.388 (DOI: 10.2152/jmi.70.388, PubMed: 37940523)
3.	Seiya Inoue, Masakazu Goto, Takashi Shono, Haruka Takasugi, Satoshi Fujiwara and Hiromitsu Takizawa : Therapeutic Strategy for Chylothorax After Esophagectomy: Lymphangiography with an Inguinal Intranodal Approach, The Indian Journal of Surgery, Vol.85, No.6, 1421-1426, 2023. (Link to Publication Site) ● Publication site (DOI): 10.1007/s12262-023-03773-5 (Link to Search Site for Scientific Articles) ● Summary page in Scopus @ Elsevier: 2-s2.0-85153283320 (DOI: 10.1007/s12262-023-03773-5, Elsevier: Scopus)
4.	Naoki Miyamoto, Hiroaki Inoue, Tomohiro Inui, Souichiro Sasa, Mariko Aoyama, Kazumasa Okumura, Hiroaki Toba, Naoki Hino, Aya Nishisho, Yukishige Sawaka, Taeko Kawanaka, Hiromitsu Takizawa and Akira Tangoku : Absolute Lymphocyte Count Changes During Neoadjuvant Chemotherapy are Associated With Prognosis of Human Epidermal Growth Factor Receptor 2-Positive Breast Cancer Patients, Clinical Breast Cancer, Vol.23, No.3, e68-e76, 2023. (Summary) Some reports have shown that absolute lymphocyte count (ALC) is associated with prognosis in breast cancer; however, the impact of ALC changes remains unclear. This study aimed to investigate the relationship between ALC changes during neoadjuvant chemotherapy for human epidermal growth factor receptor-2 (HER2)-positive breast cancer patients and disease prognosis. This retrospective cohort study January 2010 to September 2020) included patients diagnosed with HER2-positive breast cancer and treated with trastuzumab-based neoadjuvant chemotherapy. The ALC ratio was defined as the ALC value after administration of the anti-HER2 drug divided by the ALC value before administration. The optimal ALC ratio cut-off value was identified using the receiver operating characteristic curve analysis and Youden's index. The relationship between the ALC ratio and disease-free survival was assessed using the Kaplan-Meier method. Univariate and multivariate analyses were performed using the Cox proportional hazards model. Data from a total of 100 HER2-positive breast cancer patients were analyzed. The cut-off value of the ALC ratio was set as 1.142. The median follow-up period was 52.0 (range: 5.1-123.7) months. The 5-year disease-free survival rates were 88.4% and 60.9% in the high-and low-ALC ratio groups, respectively, and were significantly higher in the high-ALC ratio group (p = .0031). The ALC ratio was an independent prognostic factor in multivariate Cox proportional hazards analysis (p = .0032). HER2-positive breast cancer patients with a higher ALC ratio during trastuzumab-based neoadjuvant chemotherapy may have a better prognosis than their counterparts. (Keyword) Humans / female / Breast Neoplasms / Neoadjuvant Therapy / Retrospective Studies / Receptor, ErbB-2 / Prognosis / Trastuzumab / Disease-Free Survival / Lymphocyte Count / Antineoplastic Combined Chemotherapy Protocols (Link to Publication Site) ● Publication site (DOI): 10.1016/j.clbc.2023.01.005 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 36682907 ● Summary page in Scopus @ Elsevier: 2-s2.0-85147563272 (DOI: 10.1016/j.clbc.2023.01.005, PubMed: 36682907, Elsevier: Scopus)
5.	Atsushi Mitsuhashi, Kazuya Koyama, Hirokazu Ogino, Tania Afroj, Thi Na Nguyen, Hiroto Yoneda, Kenji Otsuka, Masamichi Sugimoto, Osamu Kondoh, Hiroshi Nokihara, Masaki Hanibuchi, Hiromitsu Takizawa, Tsutomu Shinohara and Yasuhiko Nishioka : Identification of fibrocyte cluster in tumors reveals the role in antitumor immunity by PD-L1 blockade., Cell Reports, Vol.42, No.3, 112162, 2023. (Summary) fibrocytes do not. Tumor-infiltrating fibrocytes acquire myofibroblast-like phenotypes through transforming growth factor β (TGF-β)/small mothers against decapentaplegic (SMAD) signaling. Thus, TGF-βR/SMAD inhibitor enhances the antitumor effects of dual VEGF and PD-L1 blockade by regulating fibrocyte differentiation. Fibrocytes are highlighted as regulators of the response to programmed death 1 (PD-1)/PD-L1 blockade. (Keyword) Humans / vascular endothelial growth factor / Neoplasms / B7-H1 Antigen / immunotherapy / Tumor Microenvironment (Tokushima University Institutional Repository) ● Metadata: 118888 (Link to Publication Site) ● Publication site (DOI): 10.1016/j.celrep.2023.112162 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 36870329 ● Search Scopus @ Elsevier (PMID): 36870329 ● Search Scopus @ Elsevier (DOI): 10.1016/j.celrep.2023.112162 (Tokushima University Institutional Repository: 118888, DOI: 10.1016/j.celrep.2023.112162, PubMed: 36870329)
6.	Batkhishig Munkhjargal, Kazuya Kondo, Soejima Shiho, Tegshee Bilguun, Chikako Takai, Naoya Kawakita, Hiroaki Toba and Hiromitsu Takizawa : Aberrant methylation of dipeptidyl peptidaselike 6 as a potential prognostic biomarker for lung adenocarcinoma, Oncology Letters, Vol.25, No.5, 206, 2023. (Summary) We previously performed the genome-wide screening of aberrantly methylated CpG islands (CGIs) using the paired tumorous and non-tumorous tissues of 12 lung adenocarcinomas (LADC). In comparisons with paired normal lung tissues, dipeptidyl peptidase-like 6 () has been identified as the most significantly hypermethylated CGI in LADC. is a protein that modulates A-type potassium channels in the somatodendritic compartments of neurons, which play a role in synaptic plasticity. Previous studies have showed that is downregulated in cancers, such as acute myeloid leukemia and melanoma, but upregulated in colon cancer, which is attributed to hyper- and hypomethylation, respectively. The present study investigated the methylation and expression levels of and its prognostic value in patients with LADC. The DNA methylation and mRNA expression levels of in surgically resected LADC tissues were examined by bisulfite pyrosequencing and reverse transcription-quantitative PCR, respectively. The DNA methylation and mRNA expression levels of were both significantly higher in LADC tissues compared with in normal lung tissues (n=25; P<0.0001). Overall and disease-free survival rates were significantly higher in LADC with high mRNA expression levels compared with those with low levels. In conclusion, epigenetic alterations in were significantly higher in LADC tissues compared with in normal lung tissues, which may contribute to the malignant features and worse prognosis of these patients. (Link to Publication Site) ● Publication site (DOI): 10.3892/ol.2023.13792 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 37123021 ● Search Scopus @ Elsevier (PMID): 37123021 ● Search Scopus @ Elsevier (DOI): 10.3892/ol.2023.13792 (DOI: 10.3892/ol.2023.13792, PubMed: 37123021)
7.	Naoya Kawakita, Hiroaki Toba, Shin-ichi Sakamoto, Naoki Miyamoto, Mika Takashima, Yukikiyo Kawakami, Kazuya Kondo and Hiromitsu Takizawa : Cone-beam computed tomography-guided endobronchial ultrasound using an ultrathin bronchoscope for diagnosis of peripheral pulmonary lesions: a prospective pilot study, Journal of Thoracic Disease, Vol.15, No.2, 579-588, 2023. (Summary) Multimodal transbronchial biopsy (TBB) may have improved diagnostic yield for peripheral pulmonary lesions suspected as lung cancer. Radial endobronchial ultrasound (R-EBUS) provides real-time imaging and confirmation of the location of the lesions. Cone-beam computed tomography (CBCT) can confirm that the forceps tip has reached the lesion before biopsy. Patients with peripheral pulmonary lesions and a positive computed tomography (CT) bronchus sign (based on slice thickness of 1 mm) were prospectively enrolled. An ultrathin bronchoscope (UTB) and R-EBUS probe were advanced to the target bronchus. Thereafter, forceps were advanced, and CBCT was performed. R-EBUS was performed for re-navigation, if possible. The obtained EBUS and CBCT images were classified into "within" (type 1), "adjacent to" (type 2), or "far from" (type 3), based on the probe or forceps tip. For 20 lesions, the diagnostic yield was 85%. The primary EBUS images were of types 1, 2, and 3 in 12, 6, and 2 cases, respectively. The primary CBCT images were of types 1, 2, and 3 in 12, 6, and 2 cases, respectively. Primary EBUS and CBCT image types were equivalent in 14 cases. Of the 12 cases with type 1 primary EBUS image, 9 cases had a type 1 primary CBCT image, while 3 cases exhibited positional misalignment of the forceps tip. Re-navigation was required in 8 cases with types 2 and 3 primary CBCT images. CBCT-guided TBB using an UTB and EBUS may enable real-time positioning guidance and better re-navigation in the diagnosis of peripheral pulmonary lesions. (Link to Publication Site) ● Publication site (DOI): 10.21037/jtd-22-1369 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 36910050 ● Summary page in Scopus @ Elsevier: 2-s2.0-85149631219 (DOI: 10.21037/jtd-22-1369, PubMed: 36910050, Elsevier: Scopus)
8.	Takae Bando, Kazuya Kondo, Misuzu Matsumoto, Shizuka Kuroshima, Hiromitsu Takizawa, Yoshie Imai, Aki Takahashi and Isako Ueta : Psychological Adjustment and Related Factors in Patients with Recurrence/Metastatic Lung Cancer after Curative Surgery, The Journal of Medical Investigation : JMI, Vol.70, No.1,2, 200-207, 2023. (Summary) The purpose of study was to clarify the psychological adjustment and related factors in lung cancer patients with recurrence/metastasis after curative surgery. Forty-one with lung cancer who were informed of a recurrence/metastasis after curative surgery completed a questionnaire comprised of the Mental Adjustment to Cancer Scale (MAC), Psychological Adjustment scale for Cancer Survivors (PACS), and information pertaining to demographic variables. When healthcare providers intervene in patients with lung cancer that has recurred/metastasized after curative surgery, it is necessary to assess patients' psychological adjustment based on demographic information, such as age, sex, marital status, and employment status, and to provide effective support promptly. Factors associated with psychological adjustment with recurrent/metastatic lung cancer after curative surgery were 1) female, 2) having a job, 3) over 65 years of age, 4) having a spouse, and 5) advanced-stage cancer. There was no difference in psychological adjustment between treatment and the period from cancer incidence to recurrence/metastatic. J. Med. Invest. 70 : 200-207, February, 2023. (Keyword) lung cancer / surgery / psychological adjustment / recurrence/metastasis (Tokushima University Institutional Repository) ● Metadata: 118352 (Link to Publication Site) ● Publication site (DOI): 10.2152/jmi.70.200 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 37164721 ● Search Scopus @ Elsevier (PMID): 37164721 ● Search Scopus @ Elsevier (DOI): 10.2152/jmi.70.200 (Tokushima University Institutional Repository: 118352, DOI: 10.2152/jmi.70.200, PubMed: 37164721)
9.	Hiroaki Toba, Naoya Kawakita, Shin-ichi Sakamoto and Hiromitsu Takizawa : Medical Science Digest, Vol.49, No.5, 272-273, 2023.
10.	Mariko Aoyama, Takashi Shono, Tomohiro INUI, Naoki Miyamoto, Shin-ichi Sakamoto, Seiya Inoue, Satoshi Fujiwara, Masakazu Goto, Hiroaki Toba and Hiromitsu Takizawa : Abscopal effect in a patient with solitary extramedullary plasmacytoma of the thyroid: case report, Translational Cancer Research, Vol.11, No.11, 4200-4205, 2022. (Summary) The abscopal effect is a systemic antitumor response that occurs distant to the irradiation site and is induced by local irradiation. We herein describe a case of solitary extramedullary plasmacytoma (SEP) of the thyroid in which bone metastases disappeared after thyroidectomy and cervical radiotherapy (RT). A 68-year-old man with a right cervical swelling for approximately 10 years visited a hospital with left elbow pain that persisted for 5 months. He was referred to our hospital for more detailed examinations and treatment. An immobile mass of approximately 10 cm in diameter was palpable on the right side of the patient's neck. Computed tomography (CT) showed osteolytic changes in the left humerus and right scapula, and a tumor in the right lobe of the thyroid gland. The patient was diagnosed with widely invasive follicular carcinoma and multiple bone metastases and underwent total thyroidectomy. During surgery, tumor infiltration into the trachea was observed. Shaving between the tumor and trachea was performed. Based on the results of a pathological examination, the patient was diagnosed with primary extramedullary plasmacytoma of the thyroid. After surgery, external beam RT was performed on the neck, which also reduced the pain in the left elbow. Positron emission tomography (PET)-CT showed the decreased accumulation of fluorodeoxyglucose (FDG) in the left humerus and right scapula, and the amelioration of osteolytic changes on CT. SEP of the thyroid is rare, and to the best of our knowledge, this is the first case report in which the abscopal effect was observed after thyroidectomy and cervical RT. (Link to Publication Site) ● Publication site (DOI): 10.21037/tcr-22-1419 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 36523308 ● Search Scopus @ Elsevier (PMID): 36523308 ● Search Scopus @ Elsevier (DOI): 10.21037/tcr-22-1419 (DOI: 10.21037/tcr-22-1419, PubMed: 36523308)
11.	Makoto Tobiume, Atsushi Mitsuhashi, Atsuro Saijo, Hirokazu Ogino, Tania Afroj, Hirohisa Ogawa, Hisatsugu Goto, Seidai Satou, Akane Abe, Keiko Haji, Ryohiko Ozaki, Hiromitsu Takizawa and Yasuhiko Nishioka : Analysis of the chemotactic factors for tumor-infiltrating fibrocytes and their prognostic significances in lung cancer., Oncology Letters, Vol.24, No.5, 417, 2022. (Summary) Fibrocytes, which are bone marrow-derived collagen-producing cells, have been reported to be involved in pathogenesis of pulmonary fibrosis. Our previous study reported that tumor-infiltrating fibrocytes play a role in tumor progression and drug resistance in lung cancer. The present study therefore examined chemotactic factors for fibrocytes in tissues of non-small cell lung cancer (NSCLC) and their prognostic significance. Surgically resected tumor tissues were examined for the expression of chemotactic factors, including C-X-C motif chemokine 12 (CXCL12), CCL2, platelet-derived growth factor (PDGF)-AA and PDGF-BB, as well as tumor-infiltrating fibrocytes by immunostaining. The chemotactic ability of fibrocytes in response to each factor was evaluated using a migration assay by counting the migrated cells microscopically, and expression of receptors for chemotactic factors were analyzed by flow cytometry. The expression of CXCL12, but not CCL2, PDGF-AA, or PDGF-BB, was associated with the number of tumor-infiltrating fibrocytes in lung adenocarcinoma (LUAD), but not lung squamous cell carcinoma (LUSQ). In addition, patients with an increased expression of CXCL12 in LUAD but not LUSQ showed a significantly poorer prognosis compared with those with a decreased expression. However, the expression of CCL2, PDGF-AA and PDGF-BB was not correlated with the prognosis of patients with NSCLC. The number of fibrocytes was associated with a poor prognosis in LUAD. Fibrocytes derived from the peripheral blood of healthy subjects as well as patients with lung cancer expressed higher levels of CXCR4 compared with CCR2, PDGF and receptor-α and receptor-β. Overall, these results suggested that targeting tumor-infiltrating fibrocytes via the CXCL12/CXCR4 axis may be a useful strategy for controlling the progression of NSCLC, particularly LUAD. (Link to Publication Site) ● Publication site (DOI): 10.3892/ol.2022.13537 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 36245829 ● Search Scopus @ Elsevier (PMID): 36245829 ● Search Scopus @ Elsevier (DOI): 10.3892/ol.2022.13537 (DOI: 10.3892/ol.2022.13537, PubMed: 36245829)
12.	Mariko Aoyama, Tomohiro Inui, Naoki Miyamoto, Shin-ichi Sakamoto, Seiya Inoue, Satoshi Fujiwara, Masakazu Goto, Hiroaki Toba and Hiromitsu Takizawa : A case of papillary thyroid carcinoma with renal and pulmonary metastases, Journal of Surgical Case Reports, Vol.2022, No.8, rjac366, 2022. (Summary) Distant metastases derived from papillary carcinoma are generally detected in the lungs and bones. However, renal metastasis is rare. We herein report a case of papillary thyroid carcinoma with renal and pulmonary metastases that had been initially diagnosed as primary renal carcinoma with pulmonary metastases. The lesions showed response to immune checkpoint inhibitors and tyrosine kinase inhibitor but not to radioactive iodine therapy. (Link to Publication Site) ● Publication site (DOI): 10.1093/jscr/rjac366 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 35975227 ● Search Scopus @ Elsevier (PMID): 35975227 ● Search Scopus @ Elsevier (DOI): 10.1093/jscr/rjac366 (DOI: 10.1093/jscr/rjac366, PubMed: 35975227)
13.	Souichiro Sasa, Hiroaki Inoue, INUI Tomohiro, Naoki Miyamoto, Mariko Aoyama, Kazumasa Okumura, Hiroaki Toba, Takahiro Yoshida, Tezuka Miki, Hirose Chieko, Yasuyo Saijo, Hisanori Uehara, Izumori Ayumi, Takahashi Masako, Sasa Mitsunori and Hiromitsu Takizawa : Axillary lymphangioma that developed following COVID-19 vaccination: a case report, Surgical Case Reports, Vol.8, No.1, 131, 2022. (Summary) Extensive vaccination programs are being implemented worldwide for coronavirus disease 2019 (COVID-19). With the spread of vaccination, swelling of the lymph nodes after vaccination is frequently seen. We encountered a patient who developed left axillary lymphadenoma following vaccine administration. The patient was a Japanese woman in her 80 s who had previously undergone surgery for right breast cancer. She received two injections of the Pfizer-BioNTech COVID-19 vaccine in her left arm. Approximately 3 months later, she complained of left axillary swelling, and imaging resulted in a diagnosis of left axillary lymphangioma. In accordance with the patient's wishes, we performed axillary mass resection. The pathological diagnosis was lymphangioma. Our examination findings indicated that congestion of the axillary lymph vessels might have been caused by upper-arm injections of the COVID-19 vaccine. (Link to Publication Site) ● Publication site (DOI): 10.1186/s40792-022-01488-5 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 35798903 ● Search Scopus @ Elsevier (PMID): 35798903 ● Search Scopus @ Elsevier (DOI): 10.1186/s40792-022-01488-5 (DOI: 10.1186/s40792-022-01488-5, PubMed: 35798903)
14.	Takahiro Yoshida, Takeshi Nishino, Masakazu Goto, Seiya Inoue, Satoshi Fujiwara, Hiromitsu Takizawa, Akira Tangoku, Hisanori Uehara and Yoshimi Bando : ypN0 in Patients with Definitive cN-positive Status After Preoperative Treatment Is a Prognostic Factor in Esophageal Cancer, Anticancer Research, Vol.42, No.1, 195-203, 2022. (Summary) Histopathological tumor regression grade is applied not to lymph nodes but primary tumors modified by preoperative treatments. This study focused on patients whose pathological examination at the time of surgery showed no residual tumor after chemo(radio)therapy in the primary lesion (ypT0) or lymph nodes (ypN0). A total of 87 patients with clinical stage II/III thoracic esophageal cancer underwent esophagectomy following preoperative treatments to evaluate significances between pathological response and clinical outcomes; 51 patients with clinically definitive lymph node metastasis (cN+) were analyzed as a subgroup. ypT0 rates were 20.7% and 23.5%, and ypN0 rates were 47.1% and 27.5% in the whole cohort and in the cN+ subgroup, respectively. Disease-free survival, from surgery to relapse or death, was significantly influenced by ypN status (p=0.035) but not by ypT status in the 51 patients with definitive cN+ disease. Preoperative chemoradiation was an independent favorable factor for achievement of ypN0 in the 51 patients (odds ratio=0.09; p=0.007). ypN status was a predictive factor for DFS in patients treated with docetaxel plus low-dose 5-fluorouracil and cisplatin combined chemotherapy, superior to ypT status, especially in patients with definitive cN+ disease. (Keyword) Aged / Aged, 80 and over / Antineoplastic Combined Chemotherapy Protocols / Chemoradiotherapy, Adjuvant / Cisplatin / Disease-Free Survival / Esophageal Neoplasms / Esophageal Squamous Cell Carcinoma / Esophagectomy / Female / Fluorouracil / Humans / Lymph Nodes / Lymphatic Metastasis / Male / Middle Aged / Neoadjuvant Therapy / Neoplasm Grading / Preoperative Care (Link to Publication Site) ● Publication site (DOI): 10.21873/anticanres.15473 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 34969725 ● Search Scopus @ Elsevier (PMID): 34969725 ● Search Scopus @ Elsevier (DOI): 10.21873/anticanres.15473 (DOI: 10.21873/anticanres.15473, PubMed: 34969725)
15.	Hidenori Maki, Seiya Inoue, Masakazu Goto, Takeshi Nishino, Takahiro Yoshida and Hiromitsu Takizawa : Spontaneous esophageal perforation within a hiatal hernia: A case report, International Journal of Surgery Case Reports, Vol.98, 107484, 2022. (Tokushima University Institutional Repository) ● Metadata: 118024 (Link to Publication Site) ● Publication site (DOI): 10.1016/j.ijscr.2022.107484 (Link to Search Site for Scientific Articles) ● Summary page in Scopus @ Elsevier: 2-s2.0-85136678999 (Tokushima University Institutional Repository: 118024, DOI: 10.1016/j.ijscr.2022.107484, Elsevier: Scopus)
16.	Mayumi Ikeuchi, Naoki Hino, Aya Nishisyo, Mariko Aoyama, Miyuki Kanematsu, Hiroaki Inoue, Souichiro Sasa, Tomohiro INUI, Naoki Miyamoto, Kazumasa Okumura and Hiromitsu Takizawa : Drug-induced interstitial pneumonia during perioperative chemotherapy for breast cancer, The Journal of Medical Investigation : JMI, Vol.69, No.1.2, 107-111, 2022. (Summary) Drug-induced interstitial pneumonia (DIP) that occurs during chemotherapy for breast cancer is a rare but a serious adverse event. Treatments of DIP requires interruption of breast cancer treatment, which may affect the patient's prognosis. However, there are few reports which discuss DIP during breast cancer treatments. Purpose of this report is to make clear how DIP occurred and influenced breast cancer treatment in our hospital. A total of 74 patients who started perioperative chemotherapy in Tokushima Municipal Hospital for breast cancer from January 2019 to December 2020 were evaluated for DIP. Patients' and tumors' characteristics, and regimens which caused DIP were investigated. The clinical courses of the DIP patients were also followed up. Twelve of the 74 patients developed DIP. All 12 patients had histories of cyclophosphamide administration;however, the causative drug could not be determined. Ten of the 12 patients were treated with steroids, and all the patients recovered ultimately from the interstitial pneumonia. While chemotherapy was administered in six patients after mild DIP, no relapse of pneumonia was observed. DIP during perioperative chemotherapy for breast cancer was resolved with appropriate treatment. Patients were able to resume breast cancer treatment with minimal interruption. J. Med. Invest. 69 : 107-111, February, 2022. (Keyword) breast cancer / Drug-induced interstitial pneumonia / perioperative chemotherapy (Tokushima University Institutional Repository) ● Metadata: 117020 (Link to Publication Site) ● Publication site (DOI): 10.2152/jmi.69.107 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 35466130 ● CiNii @ National Institute of Informatics (CRID): 1390854882616723072 ● Search Scopus @ Elsevier (PMID): 35466130 ● Search Scopus @ Elsevier (DOI): 10.2152/jmi.69.107 (Tokushima University Institutional Repository: 117020, DOI: 10.2152/jmi.69.107, PubMed: 35466130, CiNii: 1390854882616723072)
17.	Yukikiyo Kawakami, Hiromitsu Takizawa, Hiroaki Toba, Naoya Kawakita, Mitsuteru Yoshida, Kazuya Kondo and Akira Tangoku : Diversity of lymphatic flow in patients with lung cancer revealed by computed tomography lymphography, Interactive Cardiovascular and Thoracic Surgery, Vol.33, No.6, 871-878, 2021. (Summary) This study was conducted to verify the optimal extent of lymph node dissection or sampling during lung cancer surgery based on the sentinel node (SN) map created by computed tomography (CT) lymphography. From April 2010 to January 2015, patients with clinical stage I non-small-cell lung cancer, who were candidates for lobectomy or segmentectomy with standard hilar and mediastinal lymph node dissection, and in whom bronchus reached the tumour, were enrolled. An ultrathin bronchoscope was inserted to the target bronchus under the guidance of virtual bronchoscopic navigation images. CT images of the chest were obtained 30 s after 2.5 ml of iopamidol was injected. SNs were identified when the maximum CT attenuation value of the lymph nodes on postcontrast CT images increased by 30 Hounsfield units or more compared with the precontrast images. Patients underwent lobectomy with standard lymph node dissection. SNs were identified in 36 (87.8%) of the 41 patients. The average number of SNs was 1.6 (range, 1-4). There was 1 false negative case; therefore, the accuracy of SN identification was 97.2% (35/36). In 5 (13.9%) of 36 patients, SNs were outside the lobe-specific lymph node station range (#11i from right S1, #7 from right S1, #4R from right S8, #12u from right S8, #7 and #12l from left S1 + 2). CT lymphography demonstrated the diversity of lymphatic spreading patterns and there were cases in which lymph flows are found outside the lymph node dissection range. (Keyword) Carcinoma, Non-Small-Cell Lung / Contrast Media / Humans / Lung Neoplasms / Lymph Nodes / Lymphography / Neoplasm Staging / Sentinel Lymph Node Biopsy / Tomography, X-Ray Computed (Link to Publication Site) ● Publication site (DOI): 10.1093/icvts/ivab204 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 34322701 ● Summary page in Scopus @ Elsevier: 2-s2.0-85121244779 (DOI: 10.1093/icvts/ivab204, PubMed: 34322701, Elsevier: Scopus)
18.	Hirokazu Ogino, Makoto Tobiume, Kozo Kagawa, Hiroshi Kawano, Satoshi Sakaguchi, Atsuro Saijo, Daisuke Matsumoto, Hiromitsu Takizawa, Yuriko Morikawa, Yoshimi Bando, Hisatsugu Goto, Hiroshi Nokihara and Yasuhiko Nishioka : A Case of Radiation-associated Angiosarcoma Presenting as Massive Pleural Effusion., Internal Medicine, Vol.61, No.9, 1393-1397, 2021. (Summary) A 67-year-old man was admitted to our hospital for massive pleural effusion. He had a history of mandibular gingival carcinoma treated with radiation therapy (RT). Based on the cytology findings of pleural effusion and a thoracoscopic pleural biopsy, we finally diagnosed him with radiation-associated angiosarcoma. Retrospective cell-block immunocytochemistry with pleural effusion also showed potential utility for the diagnosis. This case highlights the importance of considering the possibility of radiation-associated secondary cancer in patients with pleural effusion who have a history of RT. (Keyword) Aged / Biopsy / Hemangiosarcoma / Humans / male / Pleural Effusion / Retrospective Studies / Thoracoscopy (Tokushima University Institutional Repository) ● Metadata: 118013 (Link to Publication Site) ● Publication site (DOI): 10.2169/internalmedicine.8195-21 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 34645765 ● Search Scopus @ Elsevier (PMID): 34645765 ● Search Scopus @ Elsevier (DOI): 10.2169/internalmedicine.8195-21 (Tokushima University Institutional Repository: 118013, DOI: 10.2169/internalmedicine.8195-21, PubMed: 34645765)
19.	Yohei Yamamoto, Naoko Matsui, Akiyuki Uzawa, Yukiko Ozawa, Tetsuya Kanai, Fumiko Oda, Hiroyuki Kondo, Izumi Ohigashi, Hiromitsu Takizawa, Kazuya Kondo, Mikio Sugano, Takashi Kitaichi, Hiroki Hata, Ryuji Kaji, Satoshi Kuwabara, Takashi Yamamura and Yuishin Izumi : Intrathymic Plasmablasts Are Affected in Patients With Myasthenia Gravis With Active Disease., Neurology® Neuroimmunology & Neuroinflammation, Vol.8, No.6, e1087, 2021. (Summary) Our findings confirmed a correlation between increased frequency of intrathymic plasmablasts and disease activity before thymectomy. We postulate that activated intrathymic plasmablasts endow pathogenic capacity in MG. (Keyword) Adolescent / adult / Aged / B-Lymphocytes / children / Child, Preschool / female / Humans / Leukocytes, Mononuclear / Lymphopoiesis / male / Middle Aged / Myasthenia Gravis / Stem Cells / T lymphocytes / Thymectomy / Thymoma / Thymus Neoplasms / Young Adult (Tokushima University Institutional Repository) ● Metadata: 116884 (Link to Publication Site) ● Publication site (DOI): 10.1212/NXI.0000000000001087 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 34561276 ● Summary page in Scopus @ Elsevier: 2-s2.0-85117018419 (Tokushima University Institutional Repository: 116884, DOI: 10.1212/NXI.0000000000001087, PubMed: 34561276, Elsevier: Scopus)
20.	Bilguun Tegshee, Kazuya Kondo, Shiho Soejima, Kyoka Muguruma, Mitsuhiro Tsuboi, Koichiro Kajiura, Yukikiyo Kawakami, Naoya Kawakita, Hiroaki Toba, Mitsuteru Yoshida, Hiromitsu Takizawa and Akira Tangoku : GHSR methylation-dependent expression of a variant ligand and receptor of the ghrelin system induces thymoma tumorigenesis, Oncology Letters, Vol.22, No.5, 793, 2021. (Summary) Our previous study reported that the DNA methylation of growth hormone secretagogue receptor () was significantly higher in thymoma or thymic carcinoma (TC) than in normal thymic tissue samples. Thymic epithelial tumors (TETs) with higher DNA methylation were associated with significantly worse prognosis than those with lower levels of DNA methylation. Diversified components of the ghrelin- axis may exert opposing effects in cancer progression, depending on the cancer type in question. However, the precise function of the axis remains unclear. In the present study, the mRNA expression of five key components of the ghrelin system [native ligand ghrelin, variant ligand In-1 ghrelin, native receptor GHSR1a, variant receptor GHSR1b and acylation enzyme ghrelin O-acyltransferase (GOAT)] were examined in 58 TET samples by reverse transcription-quantitative PCR, and protein expression of GHSR1a and GHSR1b was assessed in 20 TETs using immunohistochemistry. The results revealed that In-1 ghrelin, GHSR1b (variant forms) and GOAT were more strongly expressed in thymoma compared with thymic-adjacent tissue. By contrast, no significant differences were observed in the expression of ghrelin and GHSR1a (native forms) between thymoma and thymic tissue. The mRNA expression of In-1 ghrelin and GHSR1b (variant forms) was positively associated with methylation in thymoma tissue samples. However, a relationship was not found between ghrelin, GHSR1a or GOAT expression (native forms) and methylation in thymoma. Immunohistochemical analysis revealed that mRNA expression of GHSR1a and GHSR1b generally correlated with expression of the corresponding protein, and that the expression of GHSR1b was increased in advanced-stage TETs. These results indicate that the DNA methylation of is associated with a shift from native expression (ghrelin and GHSR1a) to variant expression (In-1 ghrelin and GHSR1b), which induces the tumorigenesis of thymoma, but not TC. (Tokushima University Institutional Repository) ● Metadata: 116971 (Link to Publication Site) ● Publication site (DOI): 10.3892/ol.2021.13054 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 34630704 ● Summary page in Scopus @ Elsevier: 2-s2.0-85115236793 (Tokushima University Institutional Repository: 116971, DOI: 10.3892/ol.2021.13054, PubMed: 34630704, Elsevier: Scopus)
21.	Masaaki Sato, Masashi Kobayashi, Jin Sakamoto, Ryuta Fukai, Hiromitsu Takizawa, Shinji Shinohara, Fumitsugu Kojima, Akira Sakurada and Jun Nakajima : The role of virtual-assisted lung mapping 2.0 combining microcoils and dye marks in deep lung resection, Journal of Thoracic and Cardiovascular Surgery, 2021. (Summary) Virtual-assisted lung mapping 2.0 is a novel preoperative bronchoscopic lung mapping technique combining the multiple dye marks of conventional virtual-assisted lung mapping with intrabronchial microcoils to navigate thoracoscopic deep lung resection. This study's purpose was to evaluate the feasibility of virtual-assisted lung mapping 2.0 in resecting deeply located pulmonary nodules with adequate margins. A multicenter, prospective single-arm study was performed from 2019 to 2020 in 8 institutions. The selection criteria were barely identifiable nodules requiring sublobar lung resections, nodules requiring resection lines reaching the inner 2/3 of the pulmonary lobe on computed tomography images in wedge resection, or the nodule center located in the inner 2/3 of the pulmonary lobe in wedge resection or segmentectomy. Resection margins larger than 2 cm or the nodule diameter were considered successful resection. Bronchoscopic placement of multiple dye marks and microcoil(s) was conducted 0 to 2 days before surgery. We analyzed 65 lesions in 64 patients. The diameter and depth of the targeted nodules and the minimum required resection depth reported as median (interquartile range) were 9 (7-13) mm, 11 (5-15) mm, and 30 (25-35) mm, respectively. Among 60 wedge resections and 5 segmentectomies, successful resection was achieved in 64 of 65 resections (98.5%; 95% confidence interval, 91.7-100). Among 75 microcoils placed, 3 showed major displacement after bronchoscopic placement. There were no severe adverse events associated with the virtual-assisted lung mapping procedure. This study demonstrated that virtual-assisted lung mapping 2.0 can facilitate successful resections for deep pulmonary nodules, overcoming the limitations of conventional virtual-assisted lung mapping. (Tokushima University Institutional Repository) ● Metadata: 117243 (Link to Publication Site) ● Publication site (DOI): 10.1016/j.jtcvs.2021.09.016 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 34654560 ● Search Scopus @ Elsevier (PMID): 34654560 ● Search Scopus @ Elsevier (DOI): 10.1016/j.jtcvs.2021.09.016 (Tokushima University Institutional Repository: 117243, DOI: 10.1016/j.jtcvs.2021.09.016, PubMed: 34654560)
22.	宮本直輝, Hiroaki Inoue, INUI Tomohiro, Soichiroh Sasa, Mariko Aoyama, Hiroaki Toba, Kazumasa Okumura, Takahiro Yoshida, Hiromitsu Takizawa and Akira Tangoku : HER2陽性乳癌患者における術前化学療法開始前の総リンパ球数は予後予測の指標となり得る, Shikoku Acta Medica, Vol.77, No.3,4, 131-136, 2021. (Summary) Purpose : Several studies have shown that peripheral hematologic parameters, such as the absolute lymphocyte count(ALC)and neutrophil to lymphocyte ratio(NLR)can predict the prognosis for malignant tumor. We investigated the relation of these parameter and prognosis before neoadjuvant chemotherapy for human epidermal growth factor receptor-2(HER2)-positive breast cancer patients. Methods : From April 2009 to March 2019, 85 patients diagnosed with HER2‐positive breast cancer and treated with trastuzumab-based neoadjuvant chemotherapy were included in this retrospective cohort study. The optimal cut-off for the NLR and ALC was identified using the receiver operating characteristic(ROC)curve analysis and Youden's index. Results : The median age of patients at the start of treatment was 58．9(range 32‐81)years. The median follow-up time for HER2-positive breast cancer patients was 52．0(range:9．8‐114．3)months. In this period, 11 patients developed recurrence. The low-ALC group showed better disease free survival than the high-ALC group(p=0．0482). There was no significant difference in disease free survival between the low- and high-NLR groups. Conclusion : ALC before neoadjuvant chemotherapy may be a predictor of prolonged disease free survival in HER2‐positive breast cancer patients. (Keyword) HER2陽性乳癌 / 総リンパ球数 / 周術期化学療法 / HER2 breast cancer / neoadjuvant chemotherapy / absolute lymphocyte counts (Tokushima University Institutional Repository) ● Metadata: 116396 (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1050008389805360256 (Tokushima University Institutional Repository: 116396, CiNii: 1050008389805360256)
23.	Hiromitsu Takizawa, Naoki Miyamoto, Shinichi Sakamoto, Mika Takashima, Daisuke Matsumoto, Naoya Kawakita, Hiroaki Toba, Yukikiyo Kawakami, Mitsuteru Yoshida, Kazuya Kondo and Akira Tangoku : Hypervascularized bronchial arteries as a risk factor for intraoperative bleeding and prolonged surgery, Journal of Thoracic Disease, Vol.13, No.8, 4731-4741, 2021. (Summary) The present study investigated whether highly vascularized bronchial arteries affect the intraoperative blood loss and the operative time of video-assisted thoracic surgery (VATS) lobectomy for patients with non-small cell lung cancer. We retrospectively collected data on consecutive pathological stage I to IIIA non-small cell lung cancer patients who underwent VATS lobectomy with systematic lymph node dissection between January 2017 and December 2019. Patients were divided into the following two groups according to bronchial artery diameters on preoperative enhanced contrast computed tomography (CT) findings: ≤2 and >2 mm groups. Among the 175 patients enrolled, risk factors for intraoperative blood loss >50 mL were being male (P=0.005), a history of smoking (P=0.01), percent forced expiratory volume in 1 s (FEV1.0%) <70% (P=0.012), squamous cell carcinoma (P=0.049), and a bronchial artery diameter >2.0 mm (P<0.001) in the unadjusted analysis, and a bronchial artery diameter >2.0 mm (P<0.001) in the multivariable analysis. Risk factors for an operative time >200 min were being male (P<0.001), a history of smoking (P=0.007), FEV1.0% <70% (P=0.011), squamous cell carcinoma (P=0.046), a bronchial artery diameter >2.0 mm (P<0.001), and experience of surgeon <10 years (P=0.011) in the unadjusted analysis, and being male (P=0.047), a bronchial artery diameter >2.0 mm (P=0.024), and experience of surgeon <10 years (P=0.047) in the multivariable analysis. Bronchial artery diameter was the most important risk factor of intraoperative bleeding and prolonged operative time during VATS lobectomy. (Tokushima University Institutional Repository) ● Metadata: 116933 (Link to Publication Site) ● Publication site (DOI): 10.21037/jtd-21-616 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 34527314 ● Summary page in Scopus @ Elsevier: 2-s2.0-85113478594 (Tokushima University Institutional Repository: 116933, DOI: 10.21037/jtd-21-616, PubMed: 34527314, Elsevier: Scopus)
24.	Toru Sawada, Hiromitsu Takizawa, Mariko Aoyama, Naoya Kawakita, Naoki Miyamoto, Shinichi Sakamoto, Mika Takashima, Daisuke Matsumoto, Hiroaki Toba, Yukikiyo Kawakami, Mitsuteru Yoshida, Kazuya Kondo and Akira Tangoku : Diagnosis of visceral pleural invasion using confocal laser endomicroscopy during lung cancer surgery, Journal of Thoracic Disease, Vol.13, No.8, 4742-4752, 2021. (Summary) Visceral pleural invasion (VPI) in lung cancer is a significant prognostic factor; however, it is difficult to diagnose preoperatively or intraoperatively. In this study, we examined the possibility of intraoperative diagnosis of VPI using confocal laser endomicroscopy (CLE). Among patients with primary lung cancer who underwent surgery between April 2018 and August 2019, those in whom the tumor was in contact with the pleura on chest computed tomography and whose pleural changes were intraoperatively confirmed were enrolled in this study. In the 35 patients who underwent lung resection (6 cases with visceral pleural infiltration), the area where pleural change was noted was observed and a short video was recorded using CLE. Based on the video images, three evaluators determined the defect ratio (0%, 25%, 50%, 75%, and 100%) of the autofluorescence-positive structure. The area under the receiver operating characteristic curve was used to evaluate the diagnostic performance for VPI. In 15 cases (3 cases with VPI), a validation study was performed for intraoperative VPI according to the cutoff value of the defect ratio of the autofluorescence-positive structure. The areas under the receiver operating characteristic curve for the defect ratio of the autofluorescence-positive structure were 0.86-0.91 for the three readers. Using defect ratio of autofluorescence-positive structure cutoff of ≥50% as predictor of VPI, the sensitivity, specificity, positive predictive value, negative predictive value, and accuracy were 83.3-100.0%, 57.7-73.1%, 35.3-41.7%, 95.0-100.0%, and 75.0-78.1%, respectively, for the three readers. In the validation study, the sensitivity was 100%, the specificity was 83.3%, and the diagnostic accuracy rate was 86.7%. The diagnosis of VPI through CLE is simple, non-invasive, and has high diagnostic accuracy rates. This method may be applicable for determining surgical procedures. (Tokushima University Institutional Repository) ● Metadata: 116384 (Link to Publication Site) ● Publication site (DOI): 10.21037/jtd-21-137 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 34527315 ● Summary page in Scopus @ Elsevier: 2-s2.0-85113558883 (Tokushima University Institutional Repository: 116384, DOI: 10.21037/jtd-21-137, PubMed: 34527315, Elsevier: Scopus)
25.	Takae Bando, Kazuya Kondo, Chiemi Onishi, Hiromitsu Takizawa, Yoshie Imai and 山田和代 : The Development of the Arm Fixation Method to Prevent Ipsilateral Shoulder Pain in Patients Undergoing Lung Resection, Journal of PeriAnesthesia Nursing, 1-7, 2021. (Summary) The aim of the present study was to investigate the efficacy of a new upper limb fixation method-body pillow position for preventing postoperative ipsilateral shoulder pain (ISP) in patients undergoing lung resection. An experimental study design was used. We conducted two comparisons (group A: the previous position using the arm fixation device; group B: the body pillow position) at random and examined an arm fixation method that is effective for ISP prophylaxis in patients undergoing surgery in the lateral decubitus position. We approached 87 patients, two were excluded, and, thus, 85 were randomly assigned to group A (n = 43) or group B (n = 42). No significant differences were observed in the frequency of ISP between groups A and B (25.6% vs 26.2%). The intensity of ISP between both groups was analyzed by a repeated-measures analysis of variance and was shown to decrease over time in 22 patients (P = .010). The intensity of ISP on postoperative days 0 to 3 was slightly lower in group B than in group A (P = .158). Risk factors for ISP were the duration of surgery (odds ratio, 1.01; 95% confidence interval, 1.00 to 1.01) and pre-existing shoulder stiffness (odds ratio, 5.15; 95% confidence interval, 1.07 to 24.83). There was no significance in the frequency of ISP between group A and group B. The intensity of ISP on postoperative days 0 to 3 was lower in group B than in group A, although there was no significant difference. It is important perspective for perioperative care providers to prevent ISP for early postoperative recovery and improvement of postoperative quality of life. These results suggested that we must consider a better position for preventing postoperative ISP in patients undergoing lung resection. (Keyword) arm fixation method / ipsilateral shoulder pain / lung resection (Link to Publication Site) ● Publication site (DOI): 10.1016/j.jopan.2020.11.003 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 34219013 ● Search Scopus @ Elsevier (PMID): 34219013 ● Search Scopus @ Elsevier (DOI): 10.1016/j.jopan.2020.11.003 (DOI: 10.1016/j.jopan.2020.11.003, PubMed: 34219013)
26.	Akira Tangoku, Hiromitsu Takizawa, Takahiro Yoshida, Masakazu Goto, Seiya Inoue and 都築英雄 : 食道癌手術における高度胸膜癒着症例への対処, Operation, Vol.75, No.7, 1069-1074, 2021. (Keyword) 胸膜癒着 / 食道亜全摘術 / 縦隔鏡下食道切除術 / キョウマクユチャク / ショクドウアゼンテキジュツ / ジュウカクキョウカショクドウセツジョジュツ (Link to Publication Site) ● Publication site (DOI): 10.18888/op.0000002281 (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1390569932783885568 ● Search Scopus @ Elsevier (DOI): 10.18888/op.0000002281 (DOI: 10.18888/op.0000002281, CiNii: 1390569932783885568)
27.	Xukai Li, Ke Xu, Renli Cen, Jinghui Deng, Zhuxue Hao, Jun Liu, Hiromitsu Takizawa, Calvin S.H.Ng, Giuseppe Marulli, Min P. Kim, Fei Cui and Jianxing He : Preoperative computer tomography-guided indocyanine green injection is associated with successful localization of small pulmonary nodules, Translational Lung Cancer Research, Vol.10, No.5, 2229-2236, 2021. (Summary) Localization of small pulmonary nodules (SPNs) is challenging in minimally invasive pulmonary resection, and it is unknown whether computer tomography (CT) guided by indocyanine green (ICG) can provide accurate localization with minimal complications. We performed a retrospective study of patients who underwent thoracoscopic resection of pulmonary nodules after CT-guided preoperative localization with ICG from May 2019 to May 2020. Demographics, procedural data, postoperative complications, and pathologic information, were collected, and an analysis of the accuracy and complications after surgery was conducted. In 471 patients, there was a total of 512 peripheral pulmonary nodules that were ≤2 cm in size. The average time for CT-guided percutaneous ICG injection for localization was 18 minutes, and 98.4% (504/512) of the nodules were successfully localized. The average size of the nodules was 9.1 mm, and the average depth from the pleural surface was 8.9 mm. Overall, 5.9% (28/471) of the patients had asymptomatic pneumothorax after localization, but none needed a tube thoracostomy. All the nodules were resected using video-assisted thoracoscopy technique. Preoperative CT-guided transthoracic ICG injection is safe and feasible for localization of small lung nodules for minimally invasive pulmonary resection. This technique should be considered for preoperative CT-guided localization of small lung nodules. (Tokushima University Institutional Repository) ● Metadata: 116984 (Link to Publication Site) ● Publication site (DOI): 10.21037/tlcr-21-425 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 34164272 ● Summary page in Scopus @ Elsevier: 2-s2.0-85106944922 (Tokushima University Institutional Repository: 116984, DOI: 10.21037/tlcr-21-425, PubMed: 34164272, Elsevier: Scopus)
28.	Shiho Soejima, Kazuya Kondo, Mitsuhiro Tsuboi, Kyoka Muguruma, B Tegshee, Yukikiyo Kawakami, Koichiro Kajiura, Naoya Kawakita, Hiroaki Toba, Mitsuteru Yoshida, Hiromitsu Takizawa and Akira Tangoku : GAD1 expression and its methylation as indicators of malignant behavior in thymic epithelial tumors, Oncology Letters, Vol.21, No.6, 483, 2021. (Summary) Thymic epithelial tumors (TETs) comprise thymomas and thymic carcinoma (TC). TC has more aggressive features and a poorer prognosis than thymomas. Genetic and epigenetic alterations in thymomas and TC have been investigated in an attempt to identify novel target molecules for TC. In the present study, genome-wide screening was performed on aberrantly methylated CpG islands in thymomas and TC, and the glutamate decarboxylase 1 gene () was identified as the 4th significantly hypermethylated CpG island in TC compared with thymomas. catalyzes the production of γ-aminobutyric acid from L-glutamic acid. expression is abundant in the brain but rare in other tissues, including the thymus. A total of 73 thymomas and 17 TC tissues were obtained from 90 patients who underwent surgery or biopsy at Tokushima University Hospital between 1990 and 2017. DNA methylation was examined by bisulfite pyrosequencing, and the mRNA and protein expression levels of were analyzed using reverse transcription-quantitative PCR and immunohistochemistry, respectively. The DNA methylation levels of were significantly higher in TC tissues than in the normal thymus and thymoma tissues, and methylation exhibited high sensitivity and specificity for discriminating between TC and thymoma. The mRNA and protein expression levels of were significantly higher in TC tissues than in thymomas. Patients with TET with high DNA hypermethylation and high mRNA and protein expression levels had significantly shorter relapse-free survival rates than those with low levels. In conclusion, significantly more epigenetic alterations were observed in TC tissues compared with in thymomas, which may contribute to the clinical features and prognosis of patients. (Tokushima University Institutional Repository) ● Metadata: 116970 (Link to Publication Site) ● Publication site (DOI): 10.3892/ol.2021.12744 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 33968199 ● Summary page in Scopus @ Elsevier: 2-s2.0-85105632213 (Tokushima University Institutional Repository: 116970, DOI: 10.3892/ol.2021.12744, PubMed: 33968199, Elsevier: Scopus)
29.	Takeshi Nishino, Hiroaki Toba, Takahiro Yoshida, Seiya Inoue, Masakazu Goto, Naoya Kawakita, Hiromitsu Takizawa, Yoshihiro Tsuruo and Akira Tangoku : Endobronchial Ultrasound Improves the Diagnosis of the Tracheobronchial Invasion of Advanced Esophageal Cancer, Annals of Surgical Oncology, Vol.28, No.11, 6398-6406, 2021. (Summary) Accurate diagnosis of the tracheobronchial invasion of advanced esophageal cancer is essential to select appropriate treatment and improve prognosis; however, it is difficult using the conventional modalities. This study aimed to clarify the diagnostic usefulness of convex probe endobronchial ultrasound (CP-EBUS) for the diagnosis of the tracheobronchial invasion of advanced esophageal cancer. We conducted a cadaveric study to clarify the changes in ultrasonic and histopathologic findings in the esophageal tumor and tracheal invasion models. Additionally, we examined CP-EBUS for patients with advanced thoracic esophageal cancer in whom tracheobronchial invasion was suspected on contrast-enhanced computed tomography (CE-CT) scan. We retrospectivity evaluated the diagnosis of CP-EBUS, comparing the pathological findings and treatment outcomes. Cadaveric esophageal tumor and tracheal invasion models showed the disappearance of the third layer observed with CP-EBUS and histologically proven interruption of the adventitia. This indicated that the third layer corresponded with the tracheal adventitia. We examined 40 patients with advanced thoracic esophageal cancer in whom tracheobronchial invasion was suspected. The precise diagnosis was pathologically confirmed in 9 of 14 patients diagnosed with cT3 who underwent radical surgery. 20 of 26 cases diagnosed with cT4b received definitive chemoradiotherapy, and 4 cases received salvage surgery and pathologically confirmed precise diagnosis. CP-EBUS is extremely useful for diagnosing the tracheobronchial invasion of advanced esophageal cancer. It could be an effective modality for determining treatment strategies in cases with a marginal surgical indication. (Keyword) Bronchoscopy / Endosonography / Esophageal Neoplasms / Humans / Lung Neoplasms / Tomography, X-Ray Computed / Trachea (Link to Publication Site) ● Publication site (DOI): 10.1245/s10434-021-09912-0 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 33826003 ● Summary page in Scopus @ Elsevier: 2-s2.0-85103949292 (DOI: 10.1245/s10434-021-09912-0, PubMed: 33826003, Elsevier: Scopus)
30.	Toru Sawada, Mitsuteru Yoshida, Koichiro Kajiura, Naoya Kawakita, Mitsuhiro Tsuboi, Hiroaki Toba, Yukikiyo Kawakami, Hiromitsu Takizawa, Kazuya Kondo and Akira Tangoku : Analyzing Bronchoscopic Damage, The Journal of the Japan Society for Respiratory Endoscopy, Vol.43, No.2, 91-96, 2021. (Summary) <p><b><i>Background.</i></b> Bronchoscopy is used in many procedures, such as endoscopic ultrasonography, tracheal stent placement, placement of Endobronchial Watanabe Spigots, and preoperative coil marking. However, bronchoscopy is a complicated procedure, and breakage can occur due to external forces. Bronchoscope breakage is associated with both adverse economic effects and patient-related consequences, since these devices are expensive and their breakage may increase the rates of complications and cause interruptions in examinations and treatments, if repairs are necessary. <b><i>Purpose.</i></b> We considered the causes of bronchoscope damage at our hospital in order to design future preventive measures and precautions. <b><i>Method.</i></b> We examined the bronchoscope type, their breakage status, and the repair costs for the 246 bronchoscopes in our department between January 2015 and November 2017. <b><i>Result.</i></b> A bronchoscope was damaged in 3 of the 246 cases, resulting in a damage rate of 1.2%. Damage to the bronchoscope occurred during yttrium-aluminium-garnet laser resection (n=2) because of thermal damage to the suction forceps port, during a right upper lobe biopsy (n=1) because of the forceps contacting the curved part, and during an endobronchial ultrasound lymph node biopsy because of damage to the tube caused by the puncture needle (n=1). <b><i>Conclusion.</i></b> All cases of breakage occurred secondary to technical factors owing to a lack of understanding of the structure of the bronchoscope and procedural instability. Bronchoscope damage increases expenses and procedural time while potentially reducing safety. The bronchoscopy procedure must be improved. Furthermore, practitioners should increase their understanding of the bronchoscope structure in order to prevent damage. Precautionary measures can be communicated through short lecture courses and education programs in order to increase practitioners' understanding of the internal structure of the bronchoscope and measures to increase procedural stability.</p> (Keyword) 破損 / 分析 / 気管支鏡 / 修理 / 故障 / Damage / Analyze / Bronchoscopy / Repair / Breakdown (Link to Publication Site) ● Publication site (DOI): 10.18907/jjsre.43.2_91 (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1390569070681319424 ● Search Scopus @ Elsevier (DOI): 10.18907/jjsre.43.2_91 (DOI: 10.18907/jjsre.43.2_91, CiNii: 1390569070681319424)
31.	Naoya Kawakita, Hiromitsu Takizawa, Hiroaki Toba, Shinichi Sakamoto, Naoki Miyamoto, Daisuke Matsumoto, Mika Takashima, Mitsuhiro Tsuboi, Mitsuteru Yoshida, Yukikiyo Kawakami, Kazuya Kondo and Akira Tangoku : Cone-beam computed tomography versus computed tomography-guided ultrathin bronchoscopic diagnosis for peripheral pulmonary lesions: A propensity score-matched analysis, Respirology, Vol.26, No.5, 477-484, 2021. (Summary) CBCT-guided TBB using a UTB under VBN is a useful method for the diagnosis of peripheral small pulmonary lesions. CBCT-guided TBB using UTB under VBN has been used as an alternative to CT-guided TBB. However, the advantage of CBCT-guided TBB using UTB under VBN over CT-guided TBB is still unknown. This study aimed to compare the diagnostic yield of CT-guided TBB and CBCT-guided TBB using a propensity score-matched analysis. Patients with peripheral pulmonary lesions ≤30 mm were included. Lesions whose bronchus could not be determined by CT were excluded. A UTB and biopsy forceps were advanced to the target bronchus under VBN, 2D-fluoroscopy and CT or CBCT. The CT-guided and CBCT-guided groups were matched for their propensity scores based on patient characteristics. We retrospectively reviewed 93 patients in the CT-guided group and 79 patients in the CBCT-guided group for this study. Furthermore, 48 distinct examination pairs were generated by propensity score matching. In the overall diagnostic yield, the CBCT-guided group showed better results (72.9%) than did the CT-guided group (47.9%) (P = 0.012). The median examination time lasted for 43 (IQR: 37-51) min in the CBCT-guided group and 50 (IQR: 43-62) min in the CT-guided group. The examination time in the CBCT-guided group was significantly shorter than that of the CT-guided group (P = 0.001). CBCT-guided TBB had a better diagnostic yield and shorter examination time than did CT-guided TBB. (Keyword) Bronchoscopy / Cone-Beam Computed Tomography / Humans / Lung Neoplasms / Propensity Score / Retrospective Studies / Tomography, X-Ray Computed (Link to Publication Site) ● Publication site (DOI): 10.1111/resp.14016 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 33615626 ● Summary page in Scopus @ Elsevier: 2-s2.0-85101160064 (DOI: 10.1111/resp.14016, PubMed: 33615626, Elsevier: Scopus)
32.	Naoki Miyamoto, Mitsuteru Yoshida, Mika Takashima, Daisuke Matsumoto, Naoya Kawakita, Mitsuhiro Tsuboi, Hiromitsu Takizawa, Kazuya Kondo, Hisashi Ishikura and Akira Tangoku : Classifying the destination of right top pulmonary vein in 31 clinical cases, General Thoracic and Cardiovascular Surgery, Vol.69, No.8, 1192-1195, 2021. (Summary) Disruption in the flow of blood vessels is of great concern during thoracic surgery. Preoperative 3-dimensional computed tomography facilitates visualization of the exact location and course of blood vessels. The right posterior upper lobe segmental vein, known as the right top pulmonary vein (RTPV), is an anomalous vein beginning at the right upper lobe and running through the posterior surface of the intermediate bronchus. We clinically investigated 31 patients with RTPV who underwent lobectomy or total resection of the right lung in our hospital or related institutions. We classified the final destination of RTPV into four types. The RTPV flowed into the left atrium in 35.5% of cases, superior pulmonary vein in 9.7%, inferior pulmonary vein in 41.9%, and independently into V6 in 12.9%. An RTPV with a diameter ≥ 5 mm was considered a main drainage vein in S2. We should pay attention to the RTPV during right lung lobectomy. (Keyword) Bronchi / Humans / Lung / Lung Neoplasms / Pulmonary Veins / Tomography, X-Ray Computed (Link to Publication Site) ● Publication site (DOI): 10.1007/s11748-021-01604-6 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 33586095 ● Search Scopus @ Elsevier (PMID): 33586095 ● Search Scopus @ Elsevier (DOI): 10.1007/s11748-021-01604-6 (DOI: 10.1007/s11748-021-01604-6, PubMed: 33586095)
33.	Shinichi Sakamoto, Hiromitsu Takizawa, Naoya Kawakita and Akira Tangoku : Lobectomy for lung cancer with a displaced left B^{1 + 2} and an anomalous pulmonary vein: a case report, Journal of Cardiothoracic Surgery, Vol.16, No.1, 15, 2021. (Summary) A displaced left B accompanied by an anomalous pulmonary vein is a rare condition involving complex structures. There is a risk of unexpected injuries to bronchi and blood vessels when patients with such anomalies undergo surgery for lung cancer. A 59-year-old male with suspected lung cancer in the left lower lobe was scheduled to undergo surgery. Chest computed tomography revealed a displaced B and hyperlobulation between S and S, while the interlobar fissure between S and S was completely fused. Three-dimensional computed tomography (3D-CT) revealed an anomalous V joining the left inferior pulmonary vein and a branch of the V running between S and S. We performed left lower lobectomy via video-assisted thoracic surgery, while taking care with the abovementioned anatomical structures. The strategy employed in this operation was to preserve V and confirm the locations of B and B when dividing the fissure. The aim of the surgical procedure performed in this case was to divide the fissure between S and the inferior lobe to reduce the risk of an unexpected bronchial injury. 3D-CT helps surgeons to understand the stereoscopic positional relationships among anatomical structures. (Keyword) Bronchi / Humans / Imaging, Three-Dimensional / Lung Neoplasms / Male / Middle Aged / Pneumonectomy / Pulmonary Veins / Thoracic Surgery, Video-Assisted / Tomography, X-Ray Computed / Vascular Malformations (Tokushima University Institutional Repository) ● Metadata: 117557 (Link to Publication Site) ● Publication site (DOI): 10.1186/s13019-021-01392-3 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 33478540 ● Search Scopus @ Elsevier (PMID): 33478540 ● Search Scopus @ Elsevier (DOI): 10.1186/s13019-021-01392-3 (Tokushima University Institutional Repository: 117557, DOI: 10.1186/s13019-021-01392-3, PubMed: 33478540)
34.	Seiya Inoue, Takahiro Yoshida, Takeshi Nishino, Masakazu Goto, Mariko Aoyama, Naoya Kawakita, Yota Yamamoto, Yoshihito Furukita, Hiromitsu Takizawa and Akira Tangoku : Biomarkers predicting the response to chemotherapy and the prognosis in patients with esophageal squamous cell carcinoma., General Thoracic and Cardiovascular Surgery, Vol.69, No.3, 525-533, 2021. (Summary) The prognosis of patients with esophageal squamous cell carcinoma (ESCC) has been improved by multidisciplinary therapy with chemoradiotherapy and surgery, but it remains poor. Advanced stage, malignant potential, and chemo-resistance contribute to the poor prognosis. Here, we attempted to identify predictive factors of the response to chemotherapy and the prognosis of ESCC patients. We examined 51 ESCC patients who were treated with chemotherapy followed by radical surgery, and 23 patients who were treated with chemotherapy alone. We conducted quantitative reverse transcription-polymerase chain reaction gene expression analysis using RNA extracted from 74 tumor tissue samples collected before chemotherapy and 67 tumor tissue samples collected after chemotherapy, focusing on PIK3CA, AKT-1, mTOR, 4E-BP1, p70S6K, PD-L1, and PD-L2. The proportions of patients with high expressions of AKT-1 and PD-L1 before chemotherapy were significantly higher among the non-responders than among the responders (p = 0.034, p = 0.020, respectively). Multivariate analyses revealed that high PD-L1 expression before chemotherapy was associated with poor response to chemotherapy (odds ratio 2.998; 95% CI 1.043-8.619; p = 0.042) and high p70S6K expression before chemotherapy was a poor prognostic factor (hazard ratio 2.518; 95% CI 1.058-5.988; p = 0.037). In addition, the patients with high expression of PD-L1 and PD-L2 in the tumors after chemotherapy had significantly worse survival than those with low expression of these genes (p = 0.012, p = 0.007, respectively). These results demonstrated that PD-L1 and p70S6K in the primary ESCC tissues were related to a poor response to chemotherapy and poor prognosis, respectively. (Keyword) Biomarkers, Tumor / Chemoradiotherapy / Esophageal Neoplasms / Esophageal Squamous Cell Carcinoma / Humans / Prognosis (Tokushima University Institutional Repository) ● Metadata: 115936 (Link to Publication Site) ● Publication site (DOI): 10.1007/s11748-021-01586-5 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 33449265 ● Summary page in Scopus @ Elsevier: 2-s2.0-85099215910 (Tokushima University Institutional Repository: 115936, DOI: 10.1007/s11748-021-01586-5, PubMed: 33449265, Elsevier: Scopus)
35.	Hiroaki Toba, Naoya Kawakita, Mika Takashima, Daisuke Matsumoto, Hiromitsu Takizawa, Hideki Otsuka and Akira Tangoku : Diagnosis of recurrence and follow-up using FDG-PET/CT for postoperative non-small-cell lung cancer patients, General Thoracic and Cardiovascular Surgery, Vol.69, No.2, 311-317, 2021. (Summary) There is currently no consensus regarding the best program for postoperative follow-up and surveillance after a curative resection for non-small-cell lung cancer (NSCLC) patients. We examined the diagnostic capability of F-fluorodeoxyglucose positron emission tomography/computed tomography (FDG-PET/CT) for detecting recurrence in postoperative NSCLC patients, and we evaluated the results of postoperative surveillance using FDG-PET/CT in asymptomatic patients. Between 2005 and 2013, 496 FDG-PET/CT examinations were performed to detect recurrences for 187 NSCLC patients who had undergone potentially curative operations at our institution. Follow-up FDG-PET/CT was performed ≥ 1 × /year in principle in 172 asymptomatic patients without clinical or radiological evidence of recurrence, and the results were retrospectively reviewed. FDG-PET/CT correctly diagnosed recurrence in 46 of 47 (97.9%) patients and 68 of 69 (98.6%) recurrent sites. The following were obtained: 97.9% sensitivity, 97.1% specificity, 92.0% positive predictive value, 99.3% negative predictive value, and 97.3% accuracy. In six patients, other diseases were detected and treated appropriately. In asymptomatic patients, the detection rate of recurrence in the stage III group was significantly higher than the detection rates in the stage I and II groups, and FDG-PET/CT performed ≤ 3 years post-resection detected significantly more FDG-positive lesions compared to that performed after 4 years. FDG-PET/CT is very useful for detecting recurrence in NSCLC patients after a potentially curative operation. It might be sufficient to perform follow-up FDG-PET/CT until 3 years post-resection for advanced-stage patients. Further randomized clinical trials are needed to determine whether the early detection of recurrences leads to better prognoses. (Keyword) Carcinoma, Non-Small-Cell Lung / Fluorodeoxyglucose F18 / Follow-Up Studies / Humans / Lung Neoplasms / Neoplasm Recurrence, Local / Positron Emission Tomography Computed Tomography / Positron-Emission Tomography / Radiopharmaceuticals / Retrospective Studies / Tomography, X-Ray Computed (Link to Publication Site) ● Publication site (DOI): 10.1007/s11748-020-01477-1 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 32909168 ● Summary page in Scopus @ Elsevier: 2-s2.0-85090755529 (DOI: 10.1007/s11748-020-01477-1, PubMed: 32909168, Elsevier: Scopus)
36.	Yukikiyo Kawakami, Kazuya Kondo, Naoya Kawakita, Hisashi Matsuoka, Hiroaki Toba, Hiromitsu Takizawa, Mitsuteru Yoshida and Akira Tangoku : Long-term outcomes of sentinel node identification using indocyanine green in patients with lung cancer, Thoracic Cancer, Vol.12, No.2, 165-171, 2021. (Tokushima University Institutional Repository) ● Metadata: 116983 (Link to Publication Site) ● Publication site (DOI): 10.1111/1759-7714.13737 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 33219734 ● Summary page in Scopus @ Elsevier: 2-s2.0-85096745669 (Tokushima University Institutional Repository: 116983, DOI: 10.1111/1759-7714.13737, PubMed: 33219734, Elsevier: Scopus)
37.	Hiroaki Toba, Hiromitsu Takizawa, Mariko Aoyama, Hiroaki Inoue and Akira Tangoku : Comprehensive Interventions for Building a Better Regional Cooperation for Cancer Patients, Journal of Japan Surgical Association, Vol.82, No.7, 1281-1285, 2021. (Summary) <p>Objectives : We introduce our comprehensive interventions for building a better regional cooperation for cancer patients. Methods : We have made a questionnaire survey for community physicians asking whether they can accept cancer patients and what types of medical treatments they can provide. Based on the questionnaire responses, we visualized the information, developed a new critical pathway, and improved the system in a basic hospital. Results : We first organized the information obtained from the questionnaire responses and uploaded the organized information to the basic hospital's homepage for public access. We then developed a new critical pathway for the cooperation among community physicians considering the prophylactic administration of a granulocyte-colony stimulating factor (G-CSF) formulation for treating cancer patients. This treatment was subsequently applied to four patients. Additionally, a community physician was matched with each patient by a medical social worker during the patients' hospitalization. We improved the basic hospital's simple electronic medical record system to reduce the physicians' workloads. As a result, the document creation could be completed within one minute, and so they could relate to approximately 10 times larger number of cases. Conclusions : Satisfactory cancer treatments can be provided for patients by building the better regional cooperative relationships and dividing the roles with community physicians in an earlier time.</p> (Keyword) がん患者の地域連携 / かかりつけ医 / 役割分担 / regional cooperation for cancer patients / community physician / division of roles (Link to Publication Site) ● Publication site (DOI): 10.3919/jjsa.82.1281 (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1390572404756753792 ● Search Scopus @ Elsevier (DOI): 10.3919/jjsa.82.1281 (DOI: 10.3919/jjsa.82.1281, CiNii: 1390572404756753792)
38.	Naoki Miyamoto, Seiya Inoue, Takeshi Nishino, Masakazu Goto, Takahiro Yoshida, Tomoko Kobayashi, Yoshimi Bando, Hiromitsu Takizawa and Akira Tangoku : A CASE OF VAGUS NERVE SCHWANNOMA DIFFICULT TO DISTINGUISH FROM LYMPH NODAL METASTASIS OF ESOPHAGEAL CANCER., The Journal of Medical Investigation : JMI, Vol.68, No.1.2, 205-208, 2021. (Summary) In this report, we describe a rare case of vagus nerve schwannoma associated with esophageal cancer. A 70-year-old man visited our hospital complaining of worsening dysphagia. His upper gastrointenstinal endoscopy revealed a mass in the esophagus. A contrast-enhanced chest computed tomography also detected a 15 mm nodule attached to the tracheal membrane. This nodule was diagnosed as a metastatic lymph node. Although the primary tumor reduced after neoadjuvant chemotherapy, the nodule remained intact ; it showed fluorodeoxyglucose accumulation on positron emission tomography. We had a clinical diagnosis of stage III after neoadjuvant chemotherapy and underwent surgery. Intraoperatively, the nodule could not be detached from the right vagus nerve ; therefore, we excised the nodule along with the adjacent vagus nerve. The nodule was pathologically diagnosed as a vagus schwannoma. The nodule was not a regional lymph node metastasis of esophageal cancer. His postoperative course was uneventful, and he is currently undergoing outpatient follow-up without recurrence. J. Med. Invest. 68 : 205-208, February, 2021. (Tokushima University Institutional Repository) ● Metadata: 116023 (Link to Publication Site) ● Publication site (DOI): 10.2152/jmi.68.205 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 33994473 ● Search Scopus @ Elsevier (PMID): 33994473 ● Search Scopus @ Elsevier (DOI): 10.2152/jmi.68.205 (Tokushima University Institutional Repository: 116023, DOI: 10.2152/jmi.68.205, PubMed: 33994473)
39.	Akira Tangoku, Hiroaki Toba, Hiroaki Inoue, Soichiroh Sasa, Kazumasa Okumura, Mariko Aoyama, INUI Tomohiro and Hiromitsu Takizawa : [ .N-1 Study]., Japanese Journal of Cancer and Chemotherapy, Vol.47, No.12, 1681-1686, 2020. (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 33342983 ● Summary page in Scopus @ Elsevier: 2-s2.0-85098745716 (PubMed: 33342983, Elsevier: Scopus)
40.	Naoya Kawakita, Hiroaki Toba, Keiko Miyoshi, Shinichi Sakamoto, Daisuke Matsumoto, Mika Takashima, Mariko Aoyama, Seiya Inoue, Masami Morimoto, Takeshi Nishino, Hiromitsu Takizawa and Akira Tangoku : Bronchioalveolar stem cells derived from mouse-induced pluripotent stem cells promote airway epithelium regeneration, Stem Cell Research & Therapy, Vol.11, No.1, 430, 2020. (Summary) Bronchioalveolar stem cells (BASCs) located at the bronchioalveolar-duct junction (BADJ) are stem cells residing in alveoli and terminal bronchioles that can self-renew and differentiate into alveolar type (AT)-1 cells, AT-2 cells, club cells, and ciliated cells. Following terminal-bronchiole injury, BASCs increase in number and promote repair. However, whether BASCs can be differentiated from mouse-induced pluripotent stem cells (iPSCs) remains unreported, and the therapeutic potential of such cells is unclear. We therefore sought to differentiate BASCs from iPSCs and examine their potential for use in the treatment of epithelial injury in terminal bronchioles. BASCs were induced using a modified protocol for differentiating mouse iPSCs into AT-2 cells. Differentiated iPSCs were intratracheally transplanted into naphthalene-treated mice. The engraftment of BASCs into the BADJ and their subsequent ability to promote repair of injury to the airway epithelium were evaluated. Flow cytometric analysis revealed that BASCs represented ~ 7% of the cells obtained. Additionally, ultrastructural analysis of these iPSC-derived BASCs via transmission electron microscopy showed that the cells containing secretory granules harboured microvilli, as well as small and immature lamellar body-like structures. When the differentiated iPSCs were intratracheally transplanted in naphthalene-induced airway epithelium injury, transplanted BASCs were found to be engrafted in the BADJ epithelium and alveolar spaces for 14 days after transplantation and to maintain the BASC phenotype. Notably, repair of the terminal-bronchiole epithelium was markedly promoted after transplantation of the differentiated iPSCs. Mouse iPSCs could be differentiated in vitro into cells that display a similar phenotype to BASCs. Given that the differentiated iPSCs promoted epithelial repair in the mouse model of naphthalene-induced airway epithelium injury, this method may serve as a basis for the development of treatments for terminal-bronchiole/alveolar-region disorders. (Tokushima University Institutional Repository) ● Metadata: 115515 (Link to Publication Site) ● Publication site (DOI): 10.1186/s13287-020-01946-7 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 33008488 ● Summary page in Scopus @ Elsevier: 2-s2.0-85092295153 (Tokushima University Institutional Repository: 115515, DOI: 10.1186/s13287-020-01946-7, PubMed: 33008488, Elsevier: Scopus)
41.	Seiya Inoue, Takahiro Yoshida, Takeshi Nishino, Masakazu Goto, Yoshihito Furukita, Yota Yamamoto, Satoshi Fujiwara, Takuya Minato, Hiroyuki Sumitomo, Yasuhiro Yuasa, Hiromitsu Takizawa and Akira Tangoku : The sterno-tracheal distance is an important factor of anastomotic leakage of retrosternal gastric tube reconstruction after esophagectomy, Esophagus, Vol.17, No.3, 264-269, 2020. (Summary) Anastomotic leakage (AL) is a serious complication after esophagectomy. The retrosternal (RS) route has been selected majorly to reduce reflux and related pneumonia and considering mediastinal recurrences. AL has been developed more in RS than posterior mediastinal (PM) route reconstruction. Therefore, we suspected the sterno-tracheal distance (STD) might be related to AL and started the selection according to the STD from 2009. A total of 221 patients who underwent a subtotal esophagectomy with gastric tube reconstruction during January 2004-April 2017 were investigated. The patients were classified into the 'after STD selection' (A; n = 144) group and the 'before STD selection' (B, n = 77) group. The incidences of and the risk factors for AL between the two groups were compared. The incidence of AL was high in the B group (18.2%), and 78.6% of the patients who developed AL were treated with RS route reconstruction. The median STDs of the patients with AL and no AL were 10.3 mm and 14.5 mm, respectively (p = 0.001). These results demonstrated that the STD was a risk factor for AL in the RS route. Based on these results, 13 mm was set as the cutoff value. After STD selection, the median STD increased from 14.0 to 17.3 mm (p = 0.001), and the incidence of AL decreased significantly from 26.2 to 11.1% in the RS route (p = 0.037). The STD was the independent risk factor for AL in the RS route. RS route reconstruction should be avoided for the patients with STD < 13 mm. (Link to Publication Site) ● Publication site (DOI): 10.1007/s10388-019-00705-9 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 31776810 ● Summary page in Scopus @ Elsevier: 2-s2.0-85075623295 (DOI: 10.1007/s10388-019-00705-9, PubMed: 31776810, Elsevier: Scopus)
42.	Naoki Miyamoto, Mitsuteru Yoshida, Mitsuhiro Tsuboi, Kenji Otsuka, Yoshimi Bando, Takumi Kakimoto, Naoya Kawakita, Hiromitsu Takizawa, Kazuya Kondo and Akira Tangoku : A case of long-term unchanged calcifying fibrous tumor, General Thoracic and Cardiovascular Surgery, Vol.68, No.12, 1587-1590, 2020. (Summary) A calcifying fibrous tumor (CFT) is a rare benign tumor that may occur in any part of the body. We report the case of an asymptomatic 21-year-old woman with thoracic tumors. Chest computed tomography showed multiple masses in the left costophrenic angle. As we were unable to diagnose the tumor with a CT-guided needle biopsy, we performed a thoracoscopic biopsy. We found smooth multilobulated masses on the pleura and multiple small nodules around the main tumors. Partial resection of the tumor was performed by VATS. Histological examination revealed that the tumor had hypocellular fibrosclerotic tissue and distributed psammomatous calcifications with inflammatory infiltrates. Immunohistochemistry demonstrated that the spindle cells were partially positive for CD34 and CD99, but negative for anaplastic lymphoma kinase-1, smooth muscle actin, BCL-2, STAT6, and S-100 protein. The tumor was diagnosed as CFT. The patient's postoperative recovery was uneventful, and no progression of the lesions was observed during follow-up. (Link to Publication Site) ● Publication site (DOI): 10.1007/s11748-020-01396-1 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 32514881 ● Summary page in Scopus @ Elsevier: 2-s2.0-85086121909 (DOI: 10.1007/s11748-020-01396-1, PubMed: 32514881, Elsevier: Scopus)
43.	Naoya Kawakita, Hiroaki Toba, Yukikiyo Kawakami, Hiromitsu Takizawa, Yoshimi Bando, Hideki Otsuka, Daisuke Matsumoto, Mika Takashima, Mitsuhiro Tsuboi, Mitsuteru Yoshida, Kazuya Kondo and Akira Tangoku : Use of a prognostic risk score that aggregates the FDG-PET/CT SUVmax, tumor size, and histologic group for predicting the prognosis of pStage I lung adenocarcinoma, International Journal of Clinical Oncology, Vol.25, No.6, 1079-1089, 2020. (Summary) pStage I includes clinicopathologically diverse groups. This study aimed to identify the prognostic factors for pStage I lung adenocarcinoma. We retrospectively reviewed 208 patients with pStage I adenocarcinomas who underwent curative resection in our institute between 2006 and 2013. The maximum standardized uptake value (SUVmax) on [F18]-fluoro-deoxy-D-glucose positron emission tomography-computed tomography (PET/CT) was evaluated. Adenocarcinomas were categorized into the following histologic groups: group 0 (minimally invasive adenocarcinoma and lepidic predominant adenocarcinoma), group 1 (papillary predominant adenocarcinoma), and group 2 (acinar predominant adenocarcinoma and all the remaining subtypes). We assessed the relationship between disease-free survival (DFS) and clinicopathological factors. Multivariate analysis of DFS demonstrated that SUVmax > 3.0 (p < 0.001), total tumor size > 20 mm (p = 0.016), and histologic groups (p < 0.05) were independent prognostic factors. The prognostic risk score (PRS) was calculated using the following equation: PRS = SUVmax (≤ 3.0: 0 point, > 3.0: 2 points) + total tumor size (≤ 20 mm: 0 point, > 20 mm: 1 point) + histologic group (group 0: 0 point, group 1: 1 point, group 2: 2 points). Patients were divided into the following three risk groups: low-risk (PRS 0-2 points, n = 136), intermediate-risk (PRS 3-4 points, n = 49), and high-risk groups (PRS 5 points, n = 13). The 5-year DFS rates were 93.2%, 50.6%, and 30.8% for the low-, intermediate-, and high-risk groups, respectively (p < 0.001). The PRS aggregating the FDG-PET/CT SUVmax, total tumor size, and histologic group predicts the prognosis of pStage I lung adenocarcinoma. (Keyword) Adenocarcinoma of Lung / Aged / Disease-Free Survival / Female / Fluorodeoxyglucose F18 / Humans / Lung Neoplasms / Male / Middle Aged / Positron Emission Tomography Computed Tomography / Prognosis / Radiopharmaceuticals / Retrospective Studies / Risk Factors / Tumor Burden (Link to Publication Site) ● Publication site (DOI): 10.1007/s10147-020-01637-6 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 32130543 ● Summary page in Scopus @ Elsevier: 2-s2.0-85081040433 (DOI: 10.1007/s10147-020-01637-6, PubMed: 32130543, Elsevier: Scopus)
44.	Mariko Aoyama, Hiromitsu Takizawa, Kiyoshige Yamamoto, Tomohiro INUI, Naoki Miyamoto, Shinichi Sakamoto, Tomoko Kobayashi, Hisanori Uehara and Akira Tangoku : Effects of excitation light intensity on parathyroid autofluorescence with a novel near-infrared fluorescence imaging system : two surgical case reports, Gland Surgery, Vol.9, No.5, 1584-1589, 2020. (Tokushima University Institutional Repository) ● Metadata: 116330 (Link to Publication Site) ● Publication site (DOI): 10.21037/gs-20-386 (Link to Search Site for Scientific Articles) ● Search Scopus @ Elsevier (DOI): 10.21037/gs-20-386 (Tokushima University Institutional Repository: 116330, DOI: 10.21037/gs-20-386)
45.	Seiya Inoue, Takahiro Yoshida, Takeshi Nishino, Masakazu Goto, Kouhei Nishioka, Keisuke Fujimoto, Mariko Aoyama, Daisuke Matsumoto, Hiromitsu Takizawa and Akira Tangoku : Safe central venous catheters for esophageal cancer treatment, The Journal of Medical Investigation : JMI, Vol.67, No.3,4, 298-303, 2020. (Summary) Introduction : Central venous catheter (CVC) use is essential for treating esophageal cancer. Peripherally inserted central catheters (PICC) are commonly used recently for improved patient comfort and safety. We compared centrally inserted central catheters (CICC) and PICC insertions and examined their safety. Methods : We retrospectively investigated complications at the catheter insertion and post-insertion for 199 patients' esophageal cancer treatment (CICC : 45, PICC : 154) from 2013 to 2018. In addition, we summarized the results of catheter tip culture. Results : No serious complications occurred at the catheter insertion in either group. The rate of complications at catheter insertion was 5.8% for PICC and 6.7% for CICC patients. Post-insertion complications were observed in 6.5% and 11.1% of patients with PICC and CICC, respectively, and this difference was not significant. The incidence of catheter-related blood stream infection (CRBSI) was significantly lower in PICC than CICC patients (0.3 vs. 1.8 / 1,000 catheter-days ; p = 0.029). Catheter-related thrombosis was observed in PICC : 0.5 and CICC : 0.6, and occlusion due to blood flow reversal was observed in PICC : 0.5 and CICC : 0.6. Conclusion : PICCs are safer and more effective than CICCs for the treatment of esophageal cancer, and reduce the incidence of CRBSI. We hope to standardize the insertion procedures, conventionalize techniques, and establish training systems. J. Med. Invest. 67 : 298-303, August, 2020. (Tokushima University Institutional Repository) ● Metadata: 115428 (Link to Publication Site) ● Publication site (DOI): 10.2152/jmi.67.298 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 33148905 ● Summary page in Scopus @ Elsevier: 2-s2.0-85095590219 (Tokushima University Institutional Repository: 115428, DOI: 10.2152/jmi.67.298, PubMed: 33148905, Elsevier: Scopus)
46.	Mariko Aoyama, Hiromitsu Takizawa, Tamaki Otani, Seiya Inoue, Naoya Kawakita, Mitsuhiro Tsuboi, Yoshimi Bando, Hisanori Uehara, Kazuya Kondo and Akira Tangoku : Noninvasive monitoring of paclitaxel and lenvatinib efficacy against anaplastic thyroid cancer in orthotopic SCID mouse models using smallanimal FDGPET/CT, Oncology Reports, Vol.44, 1709-1716, 2020. (Tokushima University Institutional Repository) ● Metadata: 115331 (Link to Publication Site) ● Publication site (DOI): 10.3892/or.2020.7720 (Link to Search Site for Scientific Articles) ● Search Scopus @ Elsevier (DOI): 10.3892/or.2020.7720 (Tokushima University Institutional Repository: 115331, DOI: 10.3892/or.2020.7720)
47.	Mitsuhiro Tsuboi, Mariko Aoyama, Hiromitsu Takizawa, Mitsuteru Yoshida, Takashi Iwata, Masashi Akaike, Hiro-omi Kanayama, Yoshihiro Tsuruo and Akira Tangoku : 内視鏡手術の教育システム, Official Journal of the Japan Association of Endocrine Surgeons and the Japanese Society of Thyroid Surgery, Vol.37, No.1, 22-26, 2020. (Link to Publication Site) ● Publication site (DOI): 10.11226/jaesjsts.37.1_22 (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1390848250117531136 ● Search Scopus @ Elsevier (DOI): 10.11226/jaesjsts.37.1_22 (DOI: 10.11226/jaesjsts.37.1_22, CiNii: 1390848250117531136)
48.	Reina Kishibuchi, Kazuya Kondo, Shiho Soejima, Mitsuhiro Tsuboi, Koichiro Kajiura, Yukikiyo Kawakami, Naoya Kawakita, Toru Sawada, Hiroaki Toba, Mitsuteru Yoshida, Hiromitsu Takizawa and Akira Tangoku : DNA methylation of GHSR, GNG4, HOXD9 and SALL3 is a common epigenetic alteration in thymic carcinoma, International Journal of Oncology, Vol.56, No.1, 315-326, 2019. (Summary) Thymic epithelial tumors comprise thymoma, thymic carcinoma and neuroendocrine tumors of the thymus. Recent studies have revealed that the incidence of somatic non-synonymous mutations is significantly higher in thymic carcinoma than in thymoma. However, limited information is currently available on epigenetic alterations in these types of cancer. In this study, we thus performed genome-wide screening of aberrantly methylated CpG islands in thymoma and thymic carcinoma using Illumina HumanMethylation450 K BeadChip. We identified 92 CpG islands significantly hypermethylated in thymic carcinoma in relation to thymoma and selected G protein subunit gamma 4 (GNG4), growth hormone secretagogue receptor (GHSR), homeobox D9 (HOXD9) and spalt like transcription factor 3 (SALL3), which are related to cancer. We examined the promoter methylation of 4 genes in 46 thymic epithelial tumors and 20 paired thymus tissues using bisulfite pyrosequencing. Promoter methylation was significantly higher in thymic carcinoma than in thymoma and revealed a high discrimination between thymic carcinoma and thymoma in all 4 genes. Promoter methylation was higher in thymic carcinoma than in the thymus. No significant differences were observed in the promoter methylation of GNG4, HOXD9, or SALL3 between thymoma and the thymus. The promoter methylation of the 4 genes was not significantly higher in advanced-stage tumors than in early-stage tumors in all thymic epithelial tumors. Among the 4 genes, relapse-free survival was significantly worse in tumors with a higher DNA methylation than in those with a lower DNA methylation in all thymic epithelial tumors. Moreover, relapse-free survival was significantly worse in thymomas with a higher DNA methylation of HOXD9 and SALL3 than in those with a lower DNA methylation. On the whole, the findings of this study indicated that the promoter methylation of cancer-related genes was significantly higher in thymic carcinoma than in thymoma and the thymus. This is a common epigenetic alteration of high diagnostic value in thymic carcinoma and may be involved in the carcinogenesis of thymic carcinoma. However, epigenetic alterations in the 3 genes, apart from GHSR, are not involved in the tumorigenesis of thymoma. (Link to Publication Site) ● Publication site (DOI): 10.3892/ijo.2019.4915 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 31746370 ● Summary page in Scopus @ Elsevier: 2-s2.0-85076979892 (DOI: 10.3892/ijo.2019.4915, PubMed: 31746370, Elsevier: Scopus)
49.	Mitsuhiro Tsuboi, Kazuya Kondo, Shiho Soejima, Koichiro Kajiura, Naoya Kawakita, Hiroaki Toba, Yukikiyo Kawakami, Mitsuteru Yoshida, Hiromitsu Takizawa and Akira Tangoku : Chromate exposure induces DNA hypermethylation of the mismatch repair gene MLH1 in lung cancer, Molecular Carcinogenesis, Vol.59, No.1, 24-31, 2019. (Summary) Hexavalent chromium is recognized as a human carcinogen. Our previous studies revealed that lung cancer (LC) in chromate-exposed workers (chromate LC) had molecular features of frequent microsatellite instability (MSI), repression of MLH1 level, and aberrant DNA methylation of several tumor-suppressor genes, including MLH1. In the present study, we quantitatively investigated MLH1-promoter methylation status using bisulfite pyrosequencing of paired tumorous/nontumorous tissues from chromate and nonchromate LCs to determine the effect of chromate exposure on MLH1-promoter methylation. The methylation level of MLH1 promoter was significantly higher in chromate LC tumors (P < .001) than nonchromate LC tumors and, among chromate LC, significantly higher in tumorous tissue than nontumorous tissue (P = .004). Moreover, the methylation level of MLH1 promoter in normal lung tissue tended to be higher in chromate LC than nonchromate LC (P = .062). In addition, LC with reduced levels of MLH1 showed significantly higher methylation levels of MLH1 promoter than LC exhibiting normal MLH1 levels (P = .019). Moreover, immunohistochemical analyses determined that levels of SUV39H1, an H3K9me2-related methyltransferase, were higher in chromate LC than nonchromate LC (P = .076). Furthermore, we evaluated three DNA double-strand break-repair genes (MRE11, RAD50, and DNA-PKcs) as possible targets of MSI by fragment-length polymorphism analysis, revealing the mutation frequency of RAD50 as significantly higher in chromate LC than nonchromate LC (P = .047). These results suggest that chromate exposure might induce MLH1 hypermethylation in LC as a mechanism of chromate-induced carcinogenesis. (Keyword) Aged / Carcinogenesis / Chromates / DNA Methylation / DNA Mismatch Repair / Humans / Lung Neoplasms / Microsatellite Instability / Middle Aged / MutL Protein Homolog 1 / Promoter Regions, Genetic (Link to Publication Site) ● Publication site (DOI): 10.1002/mc.23125 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 31579968 ● Search Scopus @ Elsevier (PMID): 31579968 ● Search Scopus @ Elsevier (DOI): 10.1002/mc.23125 (DOI: 10.1002/mc.23125, PubMed: 31579968)
50.	Mitsuhiro Tsuboi, Kazuya Kondo, Kiyoshi Masuda, Shoichiro Tange, Koichiro Kajiura, Tomohiro Kohmoto, Hiromitsu Takizawa, Issei Imoto and Akira Tangoku : Prognostic significance of GAD1 overexpression in patients with resected lung adenocarcinoma, Cancer Medicine, Vol.8, No.9, 4189-4199, 2019. (Summary) In a previous genome-wide screening, we identified hypermethylated CpG islands around glutamate decarboxylase 1 (GAD1) in lung adenocarcinoma (LADC). In this study, we aimed to investigate the methylation and expression status of GAD1 and its prognostic value in patients with LADC. GAD1 methylation and mRNA expression status were analyzed using 33 tumorous and paired non-tumorous LADC samples and publicly available datasets. The prognostic value of GAD1 overexpression was investigated using publicly available datasets of mRNA levels and 162 cases of LADC by immunohistochemistry. The methylation and mRNA expression levels of GAD1, each having a positive correlation, were significantly higher in LADC tumors than in paired non-tumorous tissues. LADC patients with higher GAD1 mRNA expression showed significantly poorer prognosis for overall survival in publicly available datasets. Higher immunoreactivity of GAD1 was significantly associated with the pathological stage, pleural invasion, lymph vessel invasion, and poorer prognosis for cancer-specific and disease-free survival. Multivariate analysis revealed that GAD1 protein overexpression is an independent prognosticator for disease-free survival. GAD1 mRNA and protein expression levels were significant prognostic factors in LADC, suggesting that they might be useful biomarkers to stratify patients with worse clinical outcomes after resection. (Tokushima University Institutional Repository) ● Metadata: 113692 (Link to Publication Site) ● Publication site (DOI): 10.1002/cam4.2345 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 31207151 ● Summary page in Scopus @ Elsevier: 2-s2.0-85071059073 (Tokushima University Institutional Repository: 113692, DOI: 10.1002/cam4.2345, PubMed: 31207151, Elsevier: Scopus)
51.	A.A.Ali Eman, Hiromitsu Takizawa, Naoya Kawakita, Toru Sawada, Mitsuhiro Tsuboi, Hiroaki Toba, Mika Takashima, Daisuke Matsumoto, Mitsuteru Yoshida, Yukikiyo Kawakami, Kazuya Kondo, El-Badrawy Khairy Mohammad and Akira Tangoku : Transbronchial Biopsy Using an Ultrathin Bronchoscope Guided by Cone-Beam Computed Tomography and Virtual Bronchoscopic Navigation in the Diagnosis of Pulmonary Nodules, Respiration, Vol.98, No.4, 321-328, 2019. (Summary) Transbronchial biopsy is a safe diagnostic approach for patients with peripheral pulmonary lesions; however, the diagnostic yield is low. This study was conducted to evaluate the feasibility and diagnostic yield of transbronchial biopsy using the combination of an ultrathin bronchoscope, virtual bronchoscopic navigation (VBN), and cone-beam computed tomography (CBCT). Patients with peripheral pulmonary lesions, no >30 mm, with the responsible bronchus, were prospectively included. An ultrathin bronchoscope and biopsy forceps were advanced to the target bronchus under VBN, 2D-fluoroscopy, and CBCT. We categorized the CBCT findings before biopsy into 3 types according to positions of the target lesion and forceps (CBCT target-forceps sign). In type A, the forceps reached the inside of the target lesion. In type C, the forceps could not reach the lesion. When the CBCT findings could not be categorized into either type A or C, the sign was categorized as type B. Although the target lesions were invisible by conventional C-arm fluoroscopy in 29 patients, CBCT visualized all 40 lesions. The overall diagnostic yield was 90.0%, and diagnostic yields for malignant and benign lesions were 92.0 and 86.7%, respectively. Diagnostic yields for CBCT target-forceps sign types A, B, and C were 100, 75.0, and 0%, respectively. Four undiagnosed patients proceeded to other diagnostic procedures based on the CBCT target-forceps sign (type B: n = 2, type C: n = 2) and were correctly diagnosed without delay. Transbronchial biopsy using an ultrathin bronchoscope guided by CBCT and VBN showed a very high yield in the diagnosis of pulmonary nodules. (Link to Publication Site) ● Publication site (DOI): 10.1159/000500228 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 31121593 ● Search Scopus @ Elsevier (PMID): 31121593 ● Search Scopus @ Elsevier (DOI): 10.1159/000500228 (DOI: 10.1159/000500228, PubMed: 31121593)
52.	Hiroaki Toba, Hiromitsu Takizawa, Takahiro Yoshida, Masami Morimoto, Mariko Aoyama, 西口京子, 宮越智寿, Hirokazu Takechi and Akira Tangoku : Regional cooperation for cancer patients : A questionnaire clarifying the roles of community doctor, Shikoku Acta Medica, Vol.75, No.1,2, 49-54, 2019. (Summary) It was suggested long ago that regional cooperation is necessary for cancer patients. Both doctors in base hospitals and community doctors understand the importance of such cooperation. Here we report the results of our widely distributed questionnaire designed to clarify the division of physicians' roles and to strengthen the relationships between base hospital and community doctors. The questionnaire asks whether community doctors can accept cancer patients and what types of medical treatment the doctors can provide for patients with esophageal cancer, lung cancer, breast cancer, and thyroid cancer. The doctors in 289 of 550 (53%) facilities completed and returned the questionnaire. About half of the community doctors responded that they can accept patients with any of the four cancers and can provide most types of the necessary medical examinations and treatments in their daily practices. Most of the community doctors indicated that they could not provide some anti-cancer drugs and supportive drug therapies for breast cancer patients. The development and implementation of a clinical pathway system could enable the participation of more community doctors and base hospital doctors. Although our findings are preliminary, they will contribute to a foundation for building better regional corporative relationships with community doctors who treat cancer patients. (Keyword) A widely distributed questionnaire / Regional corporation / Cancer patient / Community Doctor (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1050001338773434112 (CiNii: 1050001338773434112)
53.	Naoya Kawakita, Hiromitsu Takizawa, Toru Sawada, Daisuke Matsumoto, Mitsuhiro Tsuboi, Hiroaki Toba, Mitsuteru Yoshida, Yukikiyo Kawakami, Kazuya Kondo and Akira Tangoku : Indocyanine green fluorescence imaging for resection of pulmonary metastasis of hepatocellular carcinoma, Journal of Thoracic Disease, Vol.11, No.3, 944-949, 2019. (Summary) Indocyanine green (ICG) accumulates in hepatocellular carcinoma (HCC), and tumor fluorescence can be observed under irradiation with near infrared light (NIR). This study investigated the clinical utility of ICG fluorescence imaging during resection of pulmonary metastases of HCC. From April 2010 to June 2018, six patients with suspected pulmonary metastasis of HCC were enrolled prospectively. Prior to surgery, all patients underwent the ICG hepatic function test following intravenous administration of ICG (0.5 mg/kg body weight). During surgery, metastatic HCC was identified by observation of ICG fluorescence, allowing assessment of the surgical margin. Tumor fluorescence was also evaluated on cut sections. A total of 11 metastatic HCCs were resected in six patients at nine operations. Eight lesions were removed by wedge resection and 3 lesions were managed by lobectomy. During surgery, tumor fluorescence could be confirmed through the visceral pleura in 6 out of 7 lesions treated by wedge resection, while NIR irradiation was difficult for 1 lesion. For these 6 lesions, the median distance from the tumor to the visceral pleura and the median surgical margin were 0 mm (range, 0-2 mm) and 14 mm (range, 11-17 mm), respectively. When cut sections were examined, all tumors emitted fluorescence. All lesions were histologically confirmed to be metastatic HCC. In patients with pulmonary metastasis of HCC, ICG fluorescence imaging is useful for identifying the tumor and securing its margin when the lesion is peripheral and wedge resection is planned. (Tokushima University Institutional Repository) ● Metadata: 116459 (Link to Publication Site) ● Publication site (DOI): 10.21037/jtd.2019.01.107 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 31019784 ● Search Scopus @ Elsevier (PMID): 31019784 ● Search Scopus @ Elsevier (DOI): 10.21037/jtd.2019.01.107 (Tokushima University Institutional Repository: 116459, DOI: 10.21037/jtd.2019.01.107, PubMed: 31019784)
54.	Koichiro Kajiura, Shoichiro Takao, Kawano Naoko, Toru Sawada, Mitsuhiro Tsuboi, Hiroaki Toba, Mitsuteru Yoshida, Hiromitsu Takizawa, Akira Tangoku and Kazuya Kondo : Evaluation of the components of mediastinal cystic lesions using imaging techniques, The Journal of Medical Investigation : JMI, Vol.66, No.1,2, 106-111, 2019. (Summary) To identify and differentiate patients with mediastinal cysts from those with cystic tumors requiring surgery. A total of 36 patients with mediastinal cystic lesions were enrolled. The patients were separated into two groups based on pathological findings : those with mediastinal cysts (n=23) and those with mediastinal tumors (n=13). The cystic components were measured using imaging parameters including mean computed tomography (CT) value, apparent diffusion coefficient (ADC), T1 signal intensity ratio (T1SIratio), and T2 signal intensity ratio (T2SI-ratio), acquired from magnetic resonance imaging (MRI) ; and standardized maximum uptake value (SUVmax) fromF-fluorodeoxyglucose positron emission tomography/computed tomography (F-FDG PET/CT). Both groups were statistically compared. Comparative parameters between the cysts and tumors revealed the following ratios : CT value, 40.9?21.2 versus (vs) 24.8?12.9 (p = 0.019) ;SUVmax, 1.18?0.50 vs 4.32?3.52 (p = 0.003) ; ADC, 3.46?0.96 vs 2.68?0.74 (p = 0.022) ; T1SI-ratio, 1.06?0.60 vs 1.35? 0.92 (p = 0.648) ; T2SI-ratio, 5.40?1.80 vs 4.33?1.58 (p = 0.194). However, there was no correlation between FDG uptake and ADC value. SUVmax fromF-FDG PET/CT and ADC derived from MRI were effective in facilitating preoperative diagnosis to differentiate mediastinal cysts from tumors. However, these examinations may be complementary to one another, not dominant. J. Med. Invest. 66 : 106-111, February, 2019. (Keyword) Adult / Aged / Aged, 80 and over / Cysts / female / Fluorodeoxyglucose F18 / Humans / magnetic resonance imaging / male / Mediastinal Diseases / Mediastinal Neoplasms / Middle Aged / Positron Emission Tomography Computed Tomography (Tokushima University Institutional Repository) ● Metadata: 113404 (Link to Publication Site) ● Publication site (DOI): 10.2152/jmi.66.106 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 31064920 ● Summary page in Scopus @ Elsevier: 2-s2.0-85065786369 (Tokushima University Institutional Repository: 113404, DOI: 10.2152/jmi.66.106, PubMed: 31064920, Elsevier: Scopus)
55.	Naoya Kawakita, Hiroaki Toba, Shoji Sakiyama, Mitsuhiro Tsuboi, Hiromitsu Takizawa and Akira Tangoku : A case of thoracoscopic medial basal segmentectomy, International Journal of Surgery Case Reports, Vol.55, 15-17, 2019. (Summary) Isolated resection of the medial basal segment (S7) is uncommon because of its small volume, and S7 segmentectomy is considered to be difficult due to anatomical variation. We report a case of successful thoracoscopic S7 segmentectomy. A 56-year-old man was referred to our hospital with suspected pulmonary metastasis of rectal cancer. A 6-mm nodule was detected in S7. A7 and B7 branched from the basal segmental artery and bronchus, respectively, to run ventral to the inferior pulmonary vein. This made it possible to isolate A7 and B7 by an approach via the interlobar fissure. In addition, V7a and V7b were easily isolated from inferior pulmonary vein. The intersegmental plane was indicated by V7b and was transected along a demarcation line identified by using selective oxygenation via B7. B7 most commonly branches from the basal bronchus and A7 from the basal artery to run ventral to the inferior pulmonary vein. With this anatomical type, when the surgeon approaches via the interlobar fissure during surgery, A7 is identified first, B7 is seen behind A7, and the IPV is posterior to B7. Since the intersegmental plane is located ventral to the IPV, segmentectomy can be completed via the interlobar fissure approach. In patients with this pattern of pulmonary artery and bronchial anatomy, isolated S7 segmentectomy is a feasible treatment option. (Tokushima University Institutional Repository) ● Metadata: 115161 (Link to Publication Site) ● Publication site (DOI): 10.1016/j.ijscr.2018.12.004 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 30660053 ● Summary page in Scopus @ Elsevier: 2-s2.0-85059933507 (Tokushima University Institutional Repository: 115161, DOI: 10.1016/j.ijscr.2018.12.004, PubMed: 30660053, Elsevier: Scopus)
56.	Tamaki Otani, Kazuya Kondo, Hiromitsu Takizawa, Koichiro Kajiura, Haruhiko Fujino, Hideki Otsuka and Hirokazu Miyoshi : Noninvasive monitoring of cisplatin and erlotinib efficacy against lung cancer in orthotopic SCID mouse models by small animal FDGPET/CT and CT., Oncology Reports, Vol.41, No.1, 447-454, 2019. (Summary) We established patient-like models of lung cancer metastasis by orthotopically implanting human non-small cell lung cancer cell lines into SCID mice. We evaluated the utilities of small-animal computed tomography (CT) and positron-emission tomography-computed tomography (PET/CT) in these models to non-invasively and repeatedly monitor the anticancer effects of cisplatin and erlotinib. We orthotopically implanted three non-small cell lung cancer cell lines, A549, FT821 and PC-9, into SCID mice. These mice were then divided into three groups: Control, cis-diamminedichloroplatinum (II) (CDDP) (7-mg/kg CDDP, single administration intraperitoneally), and erlotinib (25 mg/kg erlotinib/day, oral administration 5 days/week). After treatment initiation, we repeatedly performed PET/CT and CT measurements and assessed anticancer effects based on tumor volumes and FDG uptake. A549 tumors were not affected by CDDP or erlotinib. FT821 tumors were highly responsive to CDDP. PC-9 tumors, which have an epidermal growth factor receptor mutation, were highly responsive to erlotinib. Histological results and metastatic rates correlated with the anticancer effects shown by CT. In our orthotopic SCID mouse lung cancer models, 18FDG-PET/CT and CT imaging non-invasively and repeatedly monitored the efficacies of cisplatin and erlotinib against not only implanted tumors, but also mediastinal lymph node metastases. (Keyword) Animals / Carcinoma, Non-Small-Cell Lung / Cell Line, Tumor / Cisplatin / Erlotinib Hydrochloride / Fluorodeoxyglucose F18 / Humans / Lung Neoplasms / Lymph Nodes / Lymphatic Metastasis / male / Mice / Mice, SCID / Positron Emission Tomography Computed Tomography / Positron-Emission Tomography / Tomography, X-Ray Computed / Tumor Burden (Link to Publication Site) ● Publication site (DOI): 10.3892/or.2018.6818 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 30365151 ● Summary page in Scopus @ Elsevier: 2-s2.0-85056802482 (DOI: 10.3892/or.2018.6818, PubMed: 30365151, Elsevier: Scopus)
57.	Akira Tangoku, Takahiro Yoshida, Hiroaki Toba, Hirokazu Takechi, Kazumasa Okumura, Takeshi Nishino, Seiya Inoue, Misako Nakagawa, Masami Morimoto, Toru Sawada, 青山万理子, 宮本直輝, 西岡康平, 藤本啓介 and Hiromitsu Takizawa : CT lymphography for superficial esophageal cancer. Lymph Node Metastasis in Gastrointestinal Cancer" Part IV. Sentinel node navigation surgery, Chapter 17, Methodology: CT lumphography, Lymph Node Metastasis in Gastrointestinal Cancer. Ed. By Natsugoe S, Springer-Verlag, Tokyo, 323-333, 2019. (Link to Publication Site) ● Publication site (DOI): 10.1007/978-981-10-4699-5_17 (Link to Search Site for Scientific Articles) ● Search Scopus @ Elsevier (DOI): 10.1007/978-981-10-4699-5_17 (DOI: 10.1007/978-981-10-4699-5_17)
58.	Hiromitsu Takizawa : 「がんゲノム医療」によせて, Journal of Japan Surgical Society, Vol.120, No.4, 442, 2019.
59.	Haruka Takasugi, Takahiro Yoshida, Takeshi Nishino, Masakazu Goto, Seiya Inoue, Daisuke Matsumoto, Tomohiro Inui, Hiromitsu Takizawa, Hideo Tsuzuki, Toshikatsu Taniki and Akira Tangoku : Acase of advanced colon cancer arising from a colonic graft foran esophago-bronchial fistula : A case report., The Journal of Medical Investigation : JMI, Vol.66, No.1.2, 190-193, 2019. (Summary) Neoplasm of a colonic graft after esophageal reconstruction is rare. We treated a colon cancer patient who developed malignancy in a colonic graft after esophagectomy and reconstruction through a retrosternal route. A male had undergone esophagectomy in his 50s due to a benign esophago-bronchial fistula. His dysphagia became exacerbated 20 years later, and further examinations showed a circumferential tumor on the esophagocolonic anastomosis. He underwent resection of the colonic graft adenocarcinoma with median sternotomy after neoadjuvant chemotherapy. Gastric tube reconstruction was performed through a retrosternal route. This report should be informative in terms of making decisions from an initial reconstruction to follow-up and choosing a therapeutic strategy for colonic graft cancer in the future. J. Med. Invest. 66 : 190-193, February, 2019. (Tokushima University Institutional Repository) ● Metadata: 113422 (Link to Publication Site) ● Publication site (DOI): 10.2152/jmi.66.190 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 31064939 ● Search Scopus @ Elsevier (PMID): 31064939 ● Search Scopus @ Elsevier (DOI): 10.2152/jmi.66.190 (Tokushima University Institutional Repository: 113422, DOI: 10.2152/jmi.66.190, PubMed: 31064939)
60.	Mariko Aoyama, Hiromitsu Takizawa, Mitsuhiro Tsuboi, Shinichi Yamasaki, Yoshihiro Tsuruo and Akira Tangoku : Surgical training in video-assisted neck surgery-based thyroidectomy using fresh frozen human cadavers., The Journal of Medical Investigation : JMI, Vol.66, No.3.4, 293-296, 2019. (Summary) Endoscopic surgery has been introduced in various surgical fields. Endoscopic surgery requires different skills from open surgery due to the restricted surgical field and difficulty in identifying anatomical structures from certain viewpoints. Therefore, surgeons need to undergo sufficient surgical training before performing such surgery in the clinical setting. We examined the utility of fresh frozen human cadavers for surgical training aimed at introducing video-assisted neck surgery (VANS) at our department. First, we performed surgical training using fresh human cadavers four times. Next, we performed hemi-thyroidectomy with VANS in 5 clinical patients. After the cadaver training and the actual surgery, the surgeons evaluated each step of the surgical procedure using a 3-point scale. In the cadaver training, the scores for steps : creation of a subcutaneous tunnel and lifting up the skin flap and pre-thyroid muscles were higher than other steps. And a tracheal injury occurred as a complication. However, we were able to recognize anatomical structures under the endoscopic view. And it was also useful for confirming the role of surgical staff and simulating the placement of surgical equipment. Surgical training using fresh frozen human cadavers was effective at introducing a new surgical method. J. Med. Invest. 66 : 293-296, August, 2019. (Tokushima University Institutional Repository) ● Metadata: 114082 (Link to Publication Site) ● Publication site (DOI): 10.2152/jmi.66.293 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 31656292 ● Summary page in Scopus @ Elsevier: 2-s2.0-85074148764 (Tokushima University Institutional Repository: 114082, DOI: 10.2152/jmi.66.293, PubMed: 31656292, Elsevier: Scopus)
61.	Mitsuhiro Tsuboi, Hiromitsu Takizawa, Takahiro Yoshida and Akira Tangoku : Mediastinal Parathyroidectomy Using a Cervical Approach Under a Pneumomediastinum, Seminars in Thoracic and Cardiovascular Surgery, Vol.30, No.4, 472-474, 2018. (Summary) Video-assisted thoracoscopic surgery (VATS) and robotic surgery are minimally invasive surgeries for mediastinal parathyroid adenomas. However, a transthoracic approach is often difficult in the cervicothoracic transition area because of the limited visual field. We report a novel minimally invasive surgery for an ectopic parathyroid adenoma in the middle mediastinum using a cervical approach under a pneumomediastinum. (Keyword) Adenoma / Aged, 80 and over / Choristoma / female / Humans / magnetic resonance imaging / Mediastinal Neoplasms / Minimally Invasive Surgical Procedures / Parathyroid Glands / Parathyroid Neoplasms / Parathyroidectomy / Pneumomediastinum, Diagnostic / Treatment Outcome (Link to Publication Site) ● Publication site (DOI): 10.1053/j.semtcvs.2018.07.007 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 30031948 ● Summary page in Scopus @ Elsevier: 2-s2.0-85051070531 (DOI: 10.1053/j.semtcvs.2018.07.007, PubMed: 30031948, Elsevier: Scopus)
62.	Mitsuhiro Tsuboi, Hiromitsu Takizawa, Takahiro Yoshida and Akira Tangoku : Mediastinal Parathyroidectomy Using a Cervical Approach Under a Pneumomediastinum., Seminars in Thoracic and Cardiovascular Surgery, Vol.S1043, No.19, 121-127, 2018. (Link to Publication Site) ● Publication site (DOI): 10.1053/j.semtcvs.2018.07.007 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 30031948 ● Summary page in Scopus @ Elsevier: 2-s2.0-85051070531 (DOI: 10.1053/j.semtcvs.2018.07.007, PubMed: 30031948, Elsevier: Scopus)
63.	Naoya Kawakita, Hiroaki Toba, Shoji Sakiyama, Toru Sawada, Mitsuhiro Tsuboi, Mitsuteru Yoshida, Yukikiyo Kawakami, Hiromitsu Takizawa, Kazuya Kondo and Akira Tangoku : Selective lobar blockade for lung resection : A report of two cases, Shikoku Acta Medica, Vol.74, No.1,2, 55-60, 2018. (Summary) There are cases in which one-lung ventilation is difficult due to contralateral lung resection or low lung function. Selective lobar blockade can improve oxygenation compared with one-lung ventilation and secure a good operative field by inducing partial collapse. We report two cases of lung resection involving selective lobar blockade. (Case1) An 80-year-old female had previously undergone right upper and middle lobectomy for multiple lung tumors. Surgery was scheduled to remove a 7‐mm ground glass opacity from the upper left lobe. Oral intubation was performed (inner diameter of intubation tube:8mm). Next, the left upper lobe bronchus was blocked with a7Fr Arndt blocker under bronchoscopy, and partial resection of the left upper lobe was conducted. (Case2) A 75-year-old male had previously undergone right upper lobectomy for pulmonary tuberculosis and had developed right chronic empyema. Surgery was scheduled to remove a 22-mm nodule from the left lingular segment. Oral intubation was performed(inner diameter of intubation tube:8．5mm). Next, the left lingual bronchus was blocked with a7Fr Arndt blocker under bronchoscopy. Left lingular segmentectomy was carried out under thoracoscopic assistance. Intraoperative oxygenation was maintained in both cases, and the release of the block due to hypoxemia was not required in either case. (Keyword) lung cancer / surgery / anesthesia / blocker (Tokushima University Institutional Repository) ● Metadata: 111579 (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1050282813458830208 (Tokushima University Institutional Repository: 111579, CiNii: 1050282813458830208)
64.	Takeshi Nishino, Takahiro Yoshida, Masakazu Goto, Seiya Inoue, Takuya Minato, Satoshi Fujiwara, Yota Yamamoto, Yoshihito Furukita, Yasuhiro Yuasa, Hiromichi Yamai, Hirokazu Takechi, Hiroaki Toba, Hiromitsu Takizawa, Mitsuteru Yoshida, Jun-ichi Seike, Takanori Miyoshi and Akira Tangoku : The effects of the herbal medicine Daikenchuto (TJ-100) after esophageal cancer resection, open-label, randomized controlled trial, Esophagus, Vol.15, No.2, 75-82, 2018. (Summary) Daikenchuto (TJ-100), a traditional Japanese herbal medicine, is widely used in Japan. Its effects on gastrointestinal motility and microcirculation and its anti-inflammatory effect are known. The purpose of this prospective randomized controlled trial was to investigate the effect of TJ-100 after esophagectomy in esophageal cancer patients. Forty patients for whom subtotal esophageal resection for esophageal cancer was planned at our institute from March 2011 to August 2013 were enrolled and divided into two groups at the point of determination of the operation schedule after informed consent was obtained: a TJ-100 (15 g/day)-treated group (n = 20) and a control group (n = 20). The primary efficacy end-points were maintenance of the nutrition condition and the recovery of gastrointestinal function. The secondary efficacy end-points were the serum C-reactive protein (CRP) level and adrenomedullin level during the postoperative course, the incidence of postoperative complications, and the length of hospital stay after surgery. We examined 39 patients because one patient in the TJ-100 group was judged as having unresectable cancer after surgery. The mean age of the TJ-100 group patients was significantly older than that of the control group patients.The rate of body weight decrease at postoperative day 21 was significantly suppressed in the TJ-100 group (3.6% vs. the control group: 7.0%, p = 0.014), but the serum albumin level was not significantly different between the groups. The recovery of gastrointestinal function regarding flatus, defecation, and oral intake showed no significant between-group differences, but postoperative bowel symptoms tended to be rare in the TJ-100 group. There was no significant between-group difference in the length of hospital stay after surgery. The serum CRP level at postoperative day 3 was 4.9 mg/dl in the TJ-100 group and 6.9 mg/dl in the control group, showing a tendency of a suppressed serum CRP level in the TJ-100 group (p = 0.126). The rate of increase in adrenomedullin tended to be high postoperatively, but there was no significant difference between the two groups. TJ-100 treatment after esophageal cancer resection has the effects of prompting the recovery of gastrointestinal motility and minimizing body weight loss, and it might suppress the excess inflammatory reaction related to surgery. (Keyword) Adrenomedullin / Aged / C-Reactive Protein / Defecation / Eating / Esophageal Neoplasms / Esophagectomy / Female / Gastrointestinal Tract / Humans / Length of Stay / Male / Middle Aged / Nutritional Status / Phytotherapy / Plant Extracts / Postoperative Complications / Prospective Studies / Recovery of Function / Serum Albumin / Weight Loss (Tokushima University Institutional Repository) ● Metadata: 115097 (Link to Publication Site) ● Publication site (DOI): 10.1007/s10388-017-0601-9 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 29892933 ● CiNii @ National Institute of Informatics (CRID): 1521699229821638272 ● Summary page in Scopus @ Elsevier: 2-s2.0-85038619573 (Tokushima University Institutional Repository: 115097, DOI: 10.1007/s10388-017-0601-9, PubMed: 29892933, CiNii: 1521699229821638272, Elsevier: Scopus)
65.	Mitsuhiro Tsuboi, Kazuya Kondo, Hiromitsu Takizawa, Naoya Kawakita, Toru Sawada, Hiroaki Toba, Yukikiyo Kawakami, Mitsuteru Yoshida, Hisashi Ishikura, Suguru Kimura and Akira Tangoku : A feasibility study of postoperative adjuvant chemotherapy with fluoropyrimidine S-1 in patients with stage II-IIIA non-small cell lung cancer., The Journal of Medical Investigation : JMI, Vol.65, 90-95, 2018. (Summary) Adjuvant chemotherapy with uracil tegafur (UFT) improved survival among patients with completely resected stage I lung adenocarcinoma. S-1, an oral dihydropyrimidine dehydrogenase (DPD)-inhibitory 5-fluorouracil, is a more potent DPD inhibitor than UFT;therefore, we hypothesized that postoperative adjuvant chemotherapy with S-1 would be effective for advanced non-small cell lung cancer (NSCLC). We conducted a feasibility study of S-1 as postoperative adjuvant chemotherapy in patients with curatively resected pathological stage bold I back 10 bold I and bold I back 10 bold I back 20 bold I A NSCLC. Adjuvant chemotherapy consisted of 9 courses (4-week administration, 2-week withdrawal) of S-1 at 80-120 mg/body per day. Twenty-four patients with completely resected NSCLC were enrolled in this study from November 2007 through December 2010. The primary endpoint was the rate of completion of the scheduled adjuvant chemotherapy. The secondary endpoints were safety, overall survival, and relapse-free survival. Five patients were censored because of disease recurrence. The planned 9 courses of S-1 were administered to completion in 8 patients. Twelve patients completed more than 70% of the planned courses. Grade 3 adverse reactions, such as elevated total bilirubin (4.2%) and pneumonitis (4.2%), were observed, but there were no Grade 4 adverse reactions. Patients who completed more than 70% of the 9 courses demonstrated better overall survival than those who completed less than 70%. Postoperative administration of S-1 may be possible with few severe adverse events as adjuvant chemotherapy for patients with curatively resected pathological stage bold I back 10 bold I -bold I back 10 bold I back 20 bold I A NSCLC. J. Med. Invest. 65:90-95, February, 2018. (Keyword) Aged / Carcinoma, Non-Small-Cell Lung / Chemotherapy, Adjuvant / Drug Combinations / Feasibility Studies / Female / Humans / Lung Neoplasms / Male / Middle Aged / Neoplasm Staging / Oxonic Acid / Tegafur (Tokushima University Institutional Repository) ● Metadata: 111417 (Link to Publication Site) ● Publication site (DOI): 10.2152/jmi.65.90 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 29593202 ● Summary page in Scopus @ Elsevier: 2-s2.0-85044443235 (Tokushima University Institutional Repository: 111417, DOI: 10.2152/jmi.65.90, PubMed: 29593202, Elsevier: Scopus)
66.	青山万理子, Hiromitsu Takizawa, Mitsuhiro Tsuboi and Akira Tangoku : A case of painful Hashimoto s thyroiditis with difficulty of different from subacute thyroiditis, Official Journal of the Japan Association of Endocrine Surgeons and the Japanese Society of Thyroid Surgery, Vol.35, No.3, 204-207, 2018. (Summary) <p>橋本病急性増悪は，橋本病に急性炎症症状を伴う稀な疾患である．今回，亜急性甲状腺炎と鑑別が困難であった橋本病急性増悪の1例を経験したので報告する．症例は14歳，女性．2年前に学校検診で橋本病と診断された．1年10カ月前に甲状腺腫大増悪，頸部右側の圧痛を認めた．血液検査所見では，甲状腺機能正常であり，抗Tg抗体277IU/mL，抗TPO抗体246IU/mLと高値であった．白血球，CRPは正常値であり，赤沈の軽度亢進を認めた．亜急性甲状腺炎もしくは橋本病急性増悪が疑われ，NSAIDsが投与された．しかし，頸部疼痛が改善せずprednisolone(PSL)投与が開始された．治療中，疼痛部位は移動した．また，血液検査所見で自己抗体値が低下したため，亜急性甲状腺炎の可能性も否定できなかった．PSL投与後，症状は軽減したが，PSL漸減で疼痛が再燃し，PSL中止が困難であった．再燃を繰り返すことから橋本病急性増悪と診断した．PSLの離脱困難なため手術の方針となり，甲状腺全摘を行った．</p> (Keyword) painful Hashimoto s thyroiditis / subacute thyroiditis / destructive thyroiditis (Link to Publication Site) ● Publication site (DOI): 10.11226/jaesjsts.35.3_204 (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1390564238045665920 ● Search Scopus @ Elsevier (DOI): 10.11226/jaesjsts.35.3_204 (DOI: 10.11226/jaesjsts.35.3_204, CiNii: 1390564238045665920)
67.	Takae Bando, Kazuya Kondo, Chiemi Onishi, Koichiro Kajiura, Hiromitsu Takizawa, Yamada Kazuyo, Sato Hiromi and Yoshie Imai : Ipsilateral shoulder pain in patients following lung resection in the decubitus position, Journal of Clinical Nursing, Vol.27, No.5-6, 1192-1197, 2017. (Summary) Aims and objectives: To examine the frequency, influencing factors and clinical course of shoulder pain in patients following lung resection. Background: Thoracoscopes have been introduced in the surgical treatment of lung cancer and allow for less invasive surgery with a minimal incision. However, decubitus position-related shoulder pain on the operated side has not yet been investigated. Design: A longitudinal descriptive study. Methods: Patients who underwent lung resection in the decubitus position. Patients were interviewed 2 days before surgery and once daily for 5 days after surgery. Interview items included background data, the concomitant use of epidural anaesthesia, operative duration, the presence of preoperative shoulder stiffness (excluding shoulder pain), type of surgery and site of operation. The intensity of pain was approximately 5 on an 11-point numerical rating scale. Descriptive statistics on patient backgrounds were obtained using SPSS Statistics 22 for Windows. Results: Of the 74 patients who underwent lung resection in a decubitus position, 30 (40.5%) developed shoulder pain on the operated side. The highest rating occurred 1 day after surgery and decreased over time. The following two factors were found to influence shoulder pain on the operated side: operative duration (Z = 2.63; p = .01) and the presence of preoperative shoulder stiffness (excluding shoulder pain) (X²= 4.16; p = .04). Conclusions: This study demonstrated that approximately 40% of patients who underwent lung resection in the decubitus position developed shoulder pain. Relevance to clinical practice: The presence of postoperative shoulder pain was related to both the duration of the operation and to the presence of preoperative shoulder stiffness. Although the shoulder pain resolves within 4 days, it causes the patient additional discomfort and distress. Therefore, further research is needed on positioning for thoracotomy in order to investigate ways to reduce or eliminate this complication of lung surgery. (Keyword) decubitus position / lobectomy / postsurgery / shoulder pain on the operated side (Tokushima University Institutional Repository) ● Metadata: 115175 (Link to Publication Site) ● Publication site (DOI): 10.1111/jocn.14163 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 29148250 ● Summary page in Scopus @ Elsevier: 2-s2.0-85041074012 (Tokushima University Institutional Repository: 115175, DOI: 10.1111/jocn.14163, PubMed: 29148250, Elsevier: Scopus)
68.	Mitsuhiro Tsuboi, Hiromitsu Takizawa, Mariko Aoyama and Akira Tangoku : Surgical treatment of locally advanced papillary thyroid carcinoma after response to lenvatinib, International Journal of Surgery Case Reports, Vol.41, 89-92, 2017. (Summary) Differentiated thyroid carcinomas (DTC) have good prognoses after complete resection. Nevertheless, when DTC is associated with an aerodigestive invasion, curative surgery is difficult to perform. However, there is no established neoadjuvant therapy for advanced DTC. A 73-year-old man with thyroid papillary carcinoma was referred to our hospital. A computed tomography examination revealed a tumor in the upper right lobe of the thyroid, and multiple bilateral enlarged lymph nodes in the neck, involving the surrounding structures. The enlarged lymph node at the right upper neck was suspected to have invaded the right internal jugular vein, and the left paratracheal lymph node was suspected to have invaded the cervical esophagus and trachea. The tumor was considered resectable; however, surgery would have been highly invasive. Therefore, we initiated neoadjuvant therapy with lenvatinib. After administration of lenvatinib, the tumor decreased in size by 84.3% and the cervical lymph nodes by 56.0%. The patient underwent a total thyroidectomy, modified neck dissection, a resection of the muscular layer of the esophagus, and a tracheal sleeve resection and reconstruction. The SELECT trial demonstrated that lenvatinib had high response rate with short response time, in patients with radioiodine-refractory DTC. The results suggested that lenvatinib could be effective as neoadjuvant therapy. For an advanced DTC that requires removal through invasive surgery, preoperative lenvatinib treatment might be one of the options for a less invasive surgery. (Tokushima University Institutional Repository) ● Metadata: 115162 (Link to Publication Site) ● Publication site (DOI): 10.1016/j.ijscr.2017.10.010 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 29055877 ● Summary page in Scopus @ Elsevier: 2-s2.0-85031818924 (Tokushima University Institutional Repository: 115162, DOI: 10.1016/j.ijscr.2017.10.010, PubMed: 29055877, Elsevier: Scopus)
69.	Mariko Aoyama, Hiromitsu Takizawa, Mitsuhiro Tsuboi, Yasushi Nakagawa and Akira Tangoku : A case of metastatic follicular thyroid carcinoma complicated with Graves' disease after total thyroidectomy, Endocrine Journal, Vol.64, No.12, 1143-1147, 2017. (Summary) Thyroid cancer and Graves' disease may present simultaneously in one patient. The incidence of the development of hyperthyroidism from metastatic differentiated thyroid carcinoma is rare. We herein report a case of metastatic follicular carcinoma complicated with Graves' disease after total thyroidectomy. A 57-year-old woman underwent right hemithyroidectomy for follicular carcinoma. Metastatic lesions appeared in the lungs and skull two years after the first surgery, and remnant thyroidectomy was performed for radioactive iodine-131 (RAI) therapy, during which the TSH receptor antibody (TRAb) was found to be negative. The patient was treated with RAI therapy four times for four years and was receiving levothyroxine suppressive therapy. Although radioiodine uptake was observed in the lesions after the fourth course of RAI therapy, metastatic lesions had progressed. Four years after the second surgery, she had heart palpitations and tremors. Laboratory data revealed hyperthyroidism and positive TRAb. She was diagnosed with Graves' disease and received a fifth course of RAI therapy. 131I scintigraphy after RAI therapy showed strong radioiodine uptake in the metastatic lesions. As a result, the sizes and numbers of metastatic lesions decreased, and thyroid function improved. Metastatic lesions produced thyroid hormone and caused hyperthyroidism. RAI therapy was effective for Graves' disease and thyroid carcinoma. (Link to Publication Site) ● Publication site (DOI): 10.1507/endocrj.EJ17-0220 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 28883260 ● Summary page in Scopus @ Elsevier: 2-s2.0-85042672335 (DOI: 10.1507/endocrj.EJ17-0220, PubMed: 28883260, Elsevier: Scopus)
70.	Naoya Kawakita, Kazuya Kondo, Hiroaki Toba, Akiko Yoneda, Hiromitsu Takizawa and Akira Tangoku : A case of atypical type A thymoma with vascular invasion and lung metastasis, General Thoracic and Cardiovascular Surgery, Vol.66, No.4, 239-242, 2017. (Summary) We present a case of type A thymoma with invasion of the left brachiocephalic vein and lung metastases. An 84-year-old man underwent extended thymectomy combined with left brachiocephalic vein reconstruction and resection of a lung metastasis. Histological examination showed vascular invasion by the tumor. The lung metastasis had high mitotic activity and slight nuclear enlargement, the so-called "atypical" features, but the main part of the primary tumor did not. However, the intravascular portion of the tumor had "atypical" histological features like the lung metastasis. It seems that "atypical" histological features are related to clinically malignant behavior. (Link to Publication Site) ● Publication site (DOI): 10.1007/s11748-017-0794-9 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 28647799 ● Summary page in Scopus @ Elsevier: 2-s2.0-85021236001 (DOI: 10.1007/s11748-017-0794-9, PubMed: 28647799, Elsevier: Scopus)
71.	Koichiro Kajiura, Hiromitsu Takizawa, Yuki Morimoto, Kiyoshi Masuda, Mitsuhiro Tsuboi, Reina Kishibuchi, Nuliamina Wusiman, Toru Sawada, Naoya Kawakita, Hiroaki Toba, Mitsuteru Yoshida, Yukikiyo Kawakami, Takuya Naruto, Issei Imoto, Akira Tangoku and Kazuya Kondo : Frequent silencing of RASSF1A by DNA methylation in thymic neuroendocrine tumours, Lung Cancer, Vol.111, 116-123, 2017. (Summary) Aberrant methylation of promoter CpG islands (CGIs) of tumour suppressor genes is a common epigenetic mechanism underlying cancer pathogenesis. The methylation patterns of thymic tumours have not been studied in detail since such tumours are rare. Herein, we sought to identify genes that could serve as epigenetic targets for thymic neuroendocrine tumour (NET) therapy. Genome-wide screening for aberrantly methylated CGIs was performed in three NET samples, seven thymic carcinoma (TC) samples, and eight type-B3 thymoma samples. The methylation status of thymic epithelial tumours (TETs) samples was validated by pyrosequencing in a larger cohort. The expression status was analysed by quantitative polymerase chain reaction (PCR) and immunohistochemistry. We identified a CGI on a novel gene, RASSF1A, which was strongly hypermethylated in NET, but not in thymic carcinoma or B3 thymoma. RASSF1A was identified as a candidate gene statistically and bibliographically, as it showed frequent CGI hypermethylation in NET by genome-wide screening. Pyrosequencing confirmed significant hypermethylation of a RASSF1A CGI in NET. Low-grade NET tissue was more strongly methylated than high-grade NET. Quantitative PCR and immunohistochemical staining revealed that RASSF1A mRNA and protein expression levels were negatively regulated by DNA methylation. RASSF1A is a tumour suppressor gene epigenetically dysregulated in NET. Aberrant methylation of RASSF1A has been reported in various tumours, but this is the first report of RASSF1A hypermethylation in TETs. RASSF1A may represent an epigenetic therapeutic target in thymic NET. (Keyword) Aged / CpG Islands / DNA Methylation / Female / Gene Expression Regulation / Gene Silencing / Humans / Male / Middle Aged / Neuroendocrine Tumors / Promoter Regions, Genetic / RNA, Messenger / Thymus Neoplasms / Tumor Suppressor Proteins (Tokushima University Institutional Repository) ● Metadata: 112475 (Link to Publication Site) ● Publication site (DOI): 10.1016/j.lungcan.2017.05.019 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 28838380 ● Summary page in Scopus @ Elsevier: 2-s2.0-85025702753 (Tokushima University Institutional Repository: 112475, DOI: 10.1016/j.lungcan.2017.05.019, PubMed: 28838380, Elsevier: Scopus)
72.	Takeshi Nishino, Hiromitsu Takizawa, 西岡康平, 藤本啓介, 宮本直輝, 青山万理子, Toru Sawada, Naoya Kawakita, Koichiro Kajiura, Hiroaki Toba, Yukikiyo Kawakami and Mitsuteru Yoshida : Malignant Pleural Mesothelioma Presenting Refractory Pneumothorax Successfully Treated by Intrapleural Administration of Diluted Fibrin Glue : Report of a Case, The Japanese Journal of Thoracic Surgery, Vol.70, No.5, 393-396, 2017. (Keyword) 悪性胸膜中皮腫 / 難治性気胸 / 胸腔内フィブリン糊注入療法 / pleural malignant mesothelioma / intractable pneumothorax / intrapleural administration of diluted fibrin glue (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 28496089 ● CiNii @ National Institute of Informatics (CRID): 1390283684942929920 ● Summary page in Scopus @ Elsevier: 2-s2.0-85031687442 (PubMed: 28496089, CiNii: 1390283684942929920, Elsevier: Scopus)
73.	Koichiro Kajiura, Kiyoshi Masuda, Takuya Naruto, Kohmoto Tomohiro, Watanabe Miki, Mitsuhiro Tsuboi, Hiromitsu Takizawa, Kazuya Kondo, Akira Tangoku and Issei Imoto : Frequent silencing of the candidate tumor suppressor TRIM58 by promoter methylation in early-stage lung adenocarcinoma, Oncotarget, Vol.8, No.2, 2890-2905, 2017. (Summary) In this study, we aimed to identify novel drivers that would be epigenetically altered through aberrant methylation in early-stage lung adenocarcinoma (LADC), regardless of the presence or absence of tobacco smoking-induced epigenetic field defects. Through genome-wide screening for aberrantly methylated CpG islands (CGIs) in 12 clinically uniform, stage-I LADC cases affecting six non-smokers and six smokers, we identified candidate tumor-suppressor genes (TSGs) inactivated by hypermethylation. Through systematic expression analyses of those candidates in panels of additional tumor samples and cell lines treated or not treated with 5-aza-deoxycitidine followed by validation analyses of cancer-specific silencing by CGI hypermethylation using a public database, we identified TRIM58 as the most prominent candidate for TSG. TRIM58 was robustly silenced by hypermethylation even in early-stage primary LADC, and the restoration of TRIM58 expression in LADC cell lines inhibited cell growth in vitro and in vivo in anchorage-dependent and -independent manners. Our findings suggest that aberrant inactivation of TRIM58 consequent to CGI hypermethylation might stimulate the early carcinogenesis of LADC regardless of smoking status; furthermore, TRIM58 methylation might be a possible early diagnostic and epigenetic therapeutic target in LADC. (Keyword) Adaptor Proteins, Signal Transducing / Adenocarcinoma / Aged / Aged, 80 and over / Animals / cell cycle / Cell Line, Tumor / Cell Proliferation / CpG Islands / DNA Methylation / Disease Models, Animal / Epigenesis, Genetic / Epigenomics / Gene Expression Profiling / Gene Expression Regulation, Neoplastic / Gene Silencing / Genes, Tumor Suppressor / Humans / Lung Neoplasms / Male / Membrane Proteins / Mice / Middle Aged / Neoplasm Staging / Promoter Regions, Genetic / Sequence Analysis, DNA / Ubiquitin (Tokushima University Institutional Repository) ● Metadata: 110044 (Link to Publication Site) ● Publication site (DOI): 10.18632/oncotarget.13761 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 27926516 ● Summary page in Scopus @ Elsevier: 2-s2.0-85009811790 (Tokushima University Institutional Repository: 110044, DOI: 10.18632/oncotarget.13761, PubMed: 27926516, Elsevier: Scopus)
74.	Mitsuteru Yoshida, Oishi Hisashi, Martinu Tereza, Hwang M. David, Hiromitsu Takizawa, Sugihara Junichi, McKee D. Trevor, Bai Xiaohui, Guana Zehong, Lua Christina, Cho Hae-Ra, Juvet Stephen, Cypel Marcelo, Keshavjee Shaf and Liu Mingyao : Pentraxin 3 deficiency enhances features of chronic rejection in a mouse orthotopic lung transplantation model, Oncotarget, Vol.9, No.9, 8489-8501, 2017. (Summary) Chronic lung allograft dysfunction (CLAD) is a serious complication after lung transplantation and thought to represent chronic rejection. Increased expression of Pentraxin 3 (PTX3), an acute phase protein, was associated with worse outcome in lung transplant patients. To determine the role of recipient PTX3 in development of chronic rejection, we used a minor alloantigen-mismatched murine orthotopic single lung transplant model. Male C57BL/10 mice were used as donors. Male PTX3 knockout (KO) mice and their wild type (WT) littermates on 129/SvEv/C57BL6/J background were used as recipients. In KO recipients, 7/13 grafted lungs were consolidated without volume recovery on CT scan, while only 2/9 WT mice showed similar graft consolidation. For grafts where lung volume could be reliably analyzed by CT scan, the lung volume recovery was significantly reduced in KO mice compared to WT. Interstitial inflammation, parenchymal fibrosis and bronchiolitis obliterans scores were significantly higher in KO mice. Presence of myofibroblasts and lymphoid aggregation was significantly enhanced in the grafts of PTX3 KO recipients. Recipient PTX3 deficiency enhanced chronic rejection-like lesions by promoting a fibrotic process in the airways and lung parenchyma. The underlying mechanisms and potential protective role of exogenous PTX3 as a therapy should be further explored. (Tokushima University Institutional Repository) ● Metadata: 113053 (Link to Publication Site) ● Publication site (DOI): 10.18632/oncotarget.23902 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 29492210 ● Summary page in Scopus @ Elsevier: 2-s2.0-85041468013 (Tokushima University Institutional Repository: 113053, DOI: 10.18632/oncotarget.23902, PubMed: 29492210, Elsevier: Scopus)
75.	Hiromitsu Takizawa, Kazuya Kondo, Naoya Kawakita, Mitsuhiro Tsuboi, Hiroaki Toba, Koichiro Kajiura, Yukikiyo Kawakami, Shoji Sakiyama, Akira Tangoku, Atsushi Morishita, Yasushi Nakagawa and Toshiyuki Hirose : Autofluorescence for the diagnosis of visceral pleural invasion in non-small-cell lung cancer, European Journal of Cardio-Thoracic Surgery, Vol.53, No.5, 987-992, 2017. (Summary) This study was conducted to evaluate the accuracy of autofluorescence as a mode of diagnosis for visceral pleural invasion of non-small-cell lung cancer compared with white-light by means of clinical questions to several thoracic surgeons. Eight independent thoracic surgeons evaluated visceral pleural invasion in 25 cases of non-small-cell lung cancer attached to the visceral pleura on lung windows of preoperative computed tomography images. At the first study meeting to evaluate the accuracy of visceral pleural invasion diagnosis using conventional white-light images, the surgeons diagnosed visceral pleural invasion based on information in preoperative computed tomography images, histological types and videos recorded with white-light mode using a thoracoscope. At the second study meeting to evaluate the accuracy of visceral pleural invasion diagnosis using autofluorescence, the same surgeons diagnosed visceral pleural invasion based on information in 2 videos recorded in white-light mode and in autofluorescence mode using the thoracoscope. The overall average sensitivity, specificity and accuracy of visceral pleural invasion diagnosis by white-light versus autofluorescence mode were 64.6% vs 83.3%, 53.9% vs 73.7% and 56.5% vs 76.0%, respectively. The sensitivity, specificity and accuracy of visceral pleural invasion diagnosis was improved through the additional use of the autofluorescence mode compared with the white-light mode alone. (Link to Publication Site) ● Publication site (DOI): 10.1093/ejcts/ezx419 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 29228249 ● Summary page in Scopus @ Elsevier: 2-s2.0-85047017205 (DOI: 10.1093/ejcts/ezx419, PubMed: 29228249, Elsevier: Scopus)
76.	Takeshi Nishino, Takahiro Yoshida, Seiya Inoue, Satoshi Fujiwara, Masakazu Goto, Takuya Minato, Yoshihito Furukita, Yota Yamamoto, Yasuhiro Yuasa, Hiromichi Yamai, Hirokazu Takechi, Hiroaki Toba, Hiromitsu Takizawa, Mitsuteru Yoshida, Jun-ichi Seike, Takanori Miyoshi and Akira Tangoku : Gender differences in clinicopathological features and prognosis of squamous cell carcinoma of the esophagus, Esophagus, Vol.14, No.2, 122-130, 2017. (Tokushima University Institutional Repository) ● Metadata: 109991 (Link to Publication Site) ● Publication site (DOI): 10.1007/s10388-016-0554-4 (Link to Search Site for Scientific Articles) ● Summary page in Scopus @ Elsevier: 2-s2.0-84988359656 (Tokushima University Institutional Repository: 109991, DOI: 10.1007/s10388-016-0554-4, Elsevier: Scopus)
77.	Takeshi Nishino, Hiromitsu Takizawa, Toru Sawada, Naoya Kawakita, Mitsuhiro Tsuboi, Koichiro Kajiura, Hiroaki Toba, Mitsuteru Yoshida, Yukikiyo Kawakami, Kazuya Kondo, Yoshiko Yamamura and Masayuki Azuma : 肺癌手術における周術期口腔機能管理の術後肺炎予防効果, The Journal of the Japanese Association for Chest Surgery, Vol.31, No.4, 432-438, 2017. (Link to Publication Site) ● Publication site (DOI): 10.2995/jacsurg.31.432 (Link to Search Site for Scientific Articles) ● Search Scopus @ Elsevier (DOI): 10.2995/jacsurg.31.432 (DOI: 10.2995/jacsurg.31.432)
78.	Takeshi Nishino, Takahiro Yoshida, Seiya Inoue, 青山万理子, Hiromitsu Takizawa, Akira Tangoku, Yoshiko Yamamura and Masayuki Azuma : 外科診療におけるチーム医療の現況と展望 4．周術期の口腔ケア-食道癌，肺癌手術における周術期口腔機能管理-, Journal of Japan Surgical Society, Vol.118, No.2, 155-160, 2017. (Keyword) 食道癌 / 肺癌 / 周術期 / 口腔機能管理 / 肺炎予防 (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1520290883087757568 (CiNii: 1520290883087757568)
79.	Naoya Kawakita, Shoji Sakiyama, Hiroaki Toba, Hiromitsu Takizawa and 広瀬敏幸 : Surgical resection after BEP therapy induced interstitial pneumonia during treatment for primary mediastinal malignant germ cell tumor, The Journal of the Japanese Association for Chest Surgery, Vol.31, No.1, 109-114, 2017. (Summary) <p>The incidence of interstitial pneumonia caused by bleomycin is increasing, dependent on the total dose. Care should be taken in the treatment of a germ cell tumor requiring high-dose administration. If interstitial pneumonia occurs during treatment for a primary mediastinal malignant germ cell tumor, it may influence the subsequent surgical treatment. We report two surgical cases of interstitial pneumonia that occurred during BEP (bleomycin+etoposide+cisplatin) therapy for a primary mediastinal malignant germ cell tumor. Case 1 was a 19-year-old man and case 2 was a 24-year-old man. They both had an anterior mediastinal tumor of around 10 cm in diameter that was diagnosed as a yolk sac tumor by needle biopsy, and received BEP therapy. Interstitial pneumonia occurred at total bleomycin doses of 360 and 330 mg, respectively. They received steroid pulse treatment 103 and 109 days after starting therapy, respectively. Thereafter, they received steroid maintenance treatment by oral administration. Because they showed the improvement of interstitial pneumonia on imaging examinations, they received residual tumor resection and partial resection of the lung 17 and 26 days after starting steroid pulse treatment, respectively. Both post-operative courses were good, without the onset of respiratory failure.</p> (Keyword) interstitial pneumonia / drug-induced lung injury / primary mediastinal malignant germ cell tumor / bleomycin (Link to Publication Site) ● Publication site (DOI): 10.2995/jacsurg.31.109 (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1390001204361262720 ● Search Scopus @ Elsevier (DOI): 10.2995/jacsurg.31.109 (DOI: 10.2995/jacsurg.31.109, CiNii: 1390001204361262720)
80.	Koichiro Kajiura, Hiromitsu Takizawa, Kazuya Kondo, Hiroaki Toba, Yukikiyo Kawakami and Akira Tangoku : A case of subcutaneous emphysema induced by a portable thoracic drainage system after pneumonectomy, The Journal of the Japanese Association for Chest Surgery, Vol.31, No.5, 610-615, 2017. (Summary) <p>A 62-year-old man was admitted to our hospital for squamous cell lung carcinoma. We performed video-assisted right pneumonectomy after the induction chemoradiation therapy. We used portable thoracic drainage systems: Thopaz<sup>®</sup> and 19-Fr blake drain<sup>®</sup>. The patient had a severe cough and showed progressive subcutaneous emphysema. Thopaz<sup>®</sup> showed little air leakage. We confirmed the absence of a fistula at the bronchial stump via bronchoscopy and the absence of air suction from outside the drainage tube. We removed the thoracic drain because we believed Thopaz<sup>®</sup> caused the subcutaneous emphysema, and the subcutaneous emphysema subsequently fully resolved.</p><p>Thopaz<sup>®</sup> regulates the mean intrathoracic pressure by supplying air to the thoracic cavity when there is an excessive negative intrathoracic pressure. The mechanism of the increased subcutaneous emphysema by Thopaz<sup>®</sup> was considered as follows: sudden elevation of the intrathoracic pressure caused by the cough moved intrathoracic air into the subcutaneous space, instead of the blake drain<sup>®</sup>. Thopaz<sup>®</sup> supplied air into the thoracic cavity to restore the excessive negative intrathoracic pressure. This cycle was repeated and the subcutaneous emphysema worsened.</p> (Keyword) portable thoracic drainage system / post-pneumonectomy / subcutaneous emphysema (Link to Publication Site) ● Publication site (DOI): 10.2995/jacsurg.31.610 (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1390282679344397440 ● Search Scopus @ Elsevier (DOI): 10.2995/jacsurg.31.610 (DOI: 10.2995/jacsurg.31.610, CiNii: 1390282679344397440)
81.	宮本直輝, Naoya Kawakita, Toru Sawada, Hiroaki Toba, Mitsuteru Yoshida and Hiromitsu Takizawa : A case report of perivascular epithelioid cell tumor of the lung: A benign tumor with intense FDG uptake, The Journal of the Japanese Association for Chest Surgery, Vol.31, No.5, 638-642, 2017. (Summary) <p>The patient was a 36-year-old who was undergoing follow-up observation after a mediastinal mass was identified during a physical examination at a local clinic 3 years earlier. Over time, the mass showed a tendency to grow, and so the subject consulted our hospital for close examination and treatment. Chest CT revealed a mass shadow of 36 mm in the left middle mediastinum, and FDG-PET/CT revealed FDG uptake with an SUVmax of 4.93 at the same site. On suspicion of a mediastinal tumor such as a thymoma, video-assisted thoracoscopic surgery was performed; however, the lesion was a sessile intrapulmonary tumor. Rapid pathological diagnosis revealed low-grade malignancy, and left upper segmentectomy was performed. The postoperative pathology results led to the diagnosis of a benign perivascular epithelioid cell tumor (PEComa). PEComa is a rare condition, for which there are very few reports using PET/CT. We report a case of benign PEComa that showed elevated FDG uptake.</p> (Keyword) PEComa / FDG-PET/CT (Link to Publication Site) ● Publication site (DOI): 10.2995/jacsurg.31.638 (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1390001204367669248 ● Search Scopus @ Elsevier (DOI): 10.2995/jacsurg.31.638 (DOI: 10.2995/jacsurg.31.638, CiNii: 1390001204367669248)
82.	Koichiro Kajiura, Shoji Sakiyama, Kazuya Kondo, Hiroaki Toba, Hiromitsu Takizawa and Akira Tangoku : A case of aplastic anemia after thymothymectomy, The Journal of the Japanese Association for Chest Surgery, Vol.31, No.6, 815-822, 2017. (Summary) <p>Thymoma often leads to complications such as autoimmune disease, and symptoms of autoimmune disease are sometimes observed in patients even after thymothymectomy. Here, we encountered a case of aplastic anemia after thymothymectomy. A 73-year-old woman was admitted to our hospital for the treatment of an anterior mediastinal tumor. We performed thymothymectomy by median sternotomy. Histopathological findings showed type B1 thymoma when classified according to the World Health Organization system, and stage I thymoma when classified according to the Masaoka system. Six months after the surgery, the patient had pneumonia, and her hemogram showed pancytopenia; however, it had been normal before surgery. Puncture of the bone marrow showed the presence of fatty marrow, a cell density of 10-20%, and a myeloid/erythroid ratio of more than five. The patient was diagnosed with a very severe grade of aplastic anemia. Cyclosporine and supportive therapy were administered. However, the patient died of multiple organ failure 4 months after the onset of aplastic anemia.</p><p>The occurrence of aplastic anemia after thymothymectomy is a very rare complication. However, this complication is likely to be fatal since the patient becomes immunocompromised. Therefore, it is important to be careful regarding not only the recurrence of thymoma in the patient, but also the occurrence of autoimmune disease during follow-up after thymothymectomy.</p> (Keyword) post-thymothymectomy / aplastic anemia (Link to Publication Site) ● Publication site (DOI): 10.2995/jacsurg.31.815 (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1390001204366292992 ● Search Scopus @ Elsevier (DOI): 10.2995/jacsurg.31.815 (DOI: 10.2995/jacsurg.31.815, CiNii: 1390001204366292992)
83.	Takahiro Yoshida, Yoshihito Furukita, Yota Yamamoto, Takeshi Nishino, Seiya Inoue, Masami Morimoto, Kazumasa Okumura, Hiroaki Toba, Mitsuteru Yoshida, Hiromitsu Takizawa and Akira Tangoku : A randomized, open label study of the efficacy of prophylactic 24-h low-dose landiolol for atrial fibrillation in transthoracic esophagectomy, Esophagus, Vol.14, No.1, 97-103, 2017. (Link to Publication Site) ● Publication site (DOI): 10.1007/s10388-016-0553-5 (Link to Search Site for Scientific Articles) ● Summary page in Scopus @ Elsevier: 2-s2.0-84984781204 (DOI: 10.1007/s10388-016-0553-5, Elsevier: Scopus)
84.	Naoya Kawakita, Hiromitsu Takizawa, Koichiro Kajiura and Akira Tangoku : Indocyanine Green Fluorescence Intraoperative Imaging for Hepatic Hydrothorax With a Small Diaphragmatic Defect, Seminars in Thoracic and Cardiovascular Surgery, Vol.28, No.2, 606-608, 2016. (Keyword) Aged, 80 and over / Diaphragm / Disease Progression / Fatal Outcome / Fluorescent Dyes / Humans / Hydrothorax / Indocyanine Green / Intraoperative Care / Liver Cirrhosis / Male / Optical Imaging / Pleural Effusion / Predictive Value of Tests / Treatment Outcome (Tokushima University Institutional Repository) ● Metadata: 112121 (Link to Publication Site) ● Publication site (DOI): 10.1053/j.semtcvs.2016.08.006 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 28043485 ● Search Scopus @ Elsevier (PMID): 28043485 ● Search Scopus @ Elsevier (DOI): 10.1053/j.semtcvs.2016.08.006 (Tokushima University Institutional Repository: 112121, DOI: 10.1053/j.semtcvs.2016.08.006, PubMed: 28043485)
85.	Toru Sawada, 日野弘之, 松本大昌, Shin-ichi Sakamoto, Mika Takashima, Hiromitsu Takizawa, Akira Tangoku, Tsutomu Shinohara and 大串文隆 : 有瘻性膿胸に対してEWS を用いた気管支充填術と瘻孔内フィブリン糊注入の併用が有効であった1例, Shikoku Acta Medica, Vol.72, No.3-4, 137-142, 2016. (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1050564288865410432 (CiNii: 1050564288865410432)
86.	Toru Sawada, 日野弘之, 松本大昌, Shin-ichi Sakamoto, 高橋直希, Kozo Kagawa, Mika Takashima, 岡野義夫, 町田久典, 畠山暢生, Hiromitsu Takizawa, Akira Tangoku, Tsutomu Shinohara and 大串文隆 : 肺アスペルギローマ術後肺瘻に対してPushampSlide法とロープウェイ法を応用したEWS による気管支充填術が有用であった1例, Shikoku Acta Medica, Vol.72, No.3-4, 125-130, 2016. (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1050282813888700160 (CiNii: 1050282813888700160)
87.	Naoya Kawakita, Hiromitsu Takizawa, Kazuya Kondo, Shoji Sakiyama and Akira Tangoku : Indocyanine Green Fluorescence Navigation Thoracoscopic Metastasectomy for Pulmonary Metastasis of Hepatocellular Carcinoma, Annals of Thoracic and Cardiovascular Surgery, Vol.22, No.6, 367-369, 2016. (Summary) Indocyanine green can selectively accumulate in primary hepatocellular carcinoma (HCC) and extrahepatic metastases. We report a patient who underwent resection of pulmonary metastasis of HCC using a thoracoscopic near-infrared imaging system and fluorescent navigation surgery. A 66-year-old man with suspicion of pulmonary metastasis of HCC was referred to our hospital. Indocyanine green was injected intravenously at a dose of 0.5 mg/kg body weight, 20 h before thoracoscopic surgery. An endoscopic indocyanine green near-infrared fluorescence imaging system showed clear blue fluorescence, indicating pulmonary metastasis of HCC in a lingular segment. We performed wide wedge resection using the fluorescence image for navigation to confirm the surgical margins. The specimen was histologically confirmed as a pulmonary metastasis of HCC. In conclusion, thoracoscopic indocyanine green near-infrared fluorescence imaging for pulmonary metastases of HCC is useful in identifying tumor locations and ensuring resection margins. (Keyword) Aged / Carcinoma, Hepatocellular / Fluorescent Dyes / Humans / Indocyanine Green / Injections, Intravenous / Liver Neoplasms / Luminescent Measurements / Lung Neoplasms / Male / Margins of Excision / Metastasectomy / Pneumonectomy / Predictive Value of Tests / Surgery, Computer-Assisted / Thoracoscopy / Tomography, X-Ray Computed / Treatment Outcome (Tokushima University Institutional Repository) ● Metadata: 114552 (Link to Publication Site) ● Publication site (DOI): 10.5761/atcs.cr.15-00367 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 27193496 ● Summary page in Scopus @ Elsevier: 2-s2.0-85006725796 (Tokushima University Institutional Repository: 114552, DOI: 10.5761/atcs.cr.15-00367, PubMed: 27193496, Elsevier: Scopus)
88.	Yoshiko Yamamura, Hiromitsu Takizawa, Fumihiro Matsumoto, Yukihiro Momota, Keiko Aota, Daisuke Takegawa, 近藤智香, 山ノ井朋子, Hideyuki Takano, Kohichi Kani, 十川悠香, Fumiaki Kawano, Takashi Matsuo, Shoji Sakiyama and Masayuki Azuma : Effects of perioperative oral management in thoracoscopic lung lobectomy : Retrospective study, Oral Care, Vol.10, No.1, 106-110, 2016. (Keyword) 胸腔鏡下肺葉切除術 / 周術期口腔機能管理 / 術後合併症 / thoracoscopic lung lobectomy / Perioperative oral management / postoperative complications (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1522262181026542720 (CiNii: 1522262181026542720)
89.	Hirokazu Ogino, Masaki Hanibuchi, Hiromitsu Takizawa, Shoji Sakiyama, Sumitomo Hiroyuki, Seiji Iwamoto, Hitoshi Ikushima, Nakajima Kohei, Shinji Nagahiro, Yamago Taito, Yuko Toyoda, Yoshimi Bando and Yasuhiko Nishioka : Primary Pulmonary Synovial Sarcoma Showing a Prolonged Survival with Multimodality Therapy, Internal Medicine, Vol.55, No.4, 381-387, 2016. (Summary) A 54-year-old man was referred to our hospital due to a mass shadow noted on a chest X-ray. Thoracoscopic lobectomy yielded a diagnosis of primary pulmonary synovial sarcoma according to the histology and SYT-SSX1 gene analyses. Five months after the thoracic surgery, he developed brain metastasis; therefore, we performed resection of the brain metastatic focus followed by radiotherapy. As a local recurrence in the thoracic cavity concurrently emerged, systemic chemotherapy was also administered. These observations indicated that a multidisciplinary approach may be useful against primary pulmonary synovial sarcoma, although there is presently no established therapeutic strategy due to its rarity and highly aggressive nature. (Tokushima University Institutional Repository) ● Metadata: 114387 (Link to Publication Site) ● Publication site (DOI): 10.2169/internalmedicine.55.5169 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 26875964 ● Search Scopus @ Elsevier (PMID): 26875964 ● Search Scopus @ Elsevier (DOI): 10.2169/internalmedicine.55.5169 (Tokushima University Institutional Repository: 114387, DOI: 10.2169/internalmedicine.55.5169, PubMed: 26875964)
90.	Takeshi Nishino, Hiromitsu Takizawa, Takahiro Yoshida, 乾友浩, 髙杉遥, 松本大資, Naoya Kawakita, Seiya Inoue, Shoji Sakiyama, Akira Tangoku, Masayuki Azuma and Yoshiko Yamamura : Current Status and Effectiveness of Perioperative Oral Health Care Management for Lung Cancer and Esophageal Cancer Patients, The Japanese Journal of Thoracic Surgery, Vol.69, No.1, 30-34, 2016. (Keyword) 食道癌 / 肺癌 / 口腔ケア / 術後肺炎 / esophageal cancer / lung cancer / oral health care management / postoperative pneumonia (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 26975640 ● CiNii @ National Institute of Informatics (CRID): 1390283684942679808 ● Summary page in Scopus @ Elsevier: 2-s2.0-84979797876 (PubMed: 26975640, CiNii: 1390283684942679808, Elsevier: Scopus)
91.	宇山攻, Shoji Sakiyama, Mitsuteru Yoshida, Koichiro Kenzaki, Hiroaki Toba, Yukikiyo Kawakami, Kazumasa Okumura, Hiromitsu Takizawa, Kazuya Kondo and Akira Tangoku : Lung regeneration by fetal lung tissue implantation in a mouse pulmonary emphysema model, The Journal of Medical Investigation : JMI, Vol.63, No.3-4, 182-186, 2016. (Summary) The mortality and morbidity of chronic obstructive pulmonary disease are high. However, no radical therapy has been developed to date. The purpose of this study was to evaluate whether fetal mouse lung tissue can grow and differentiate in the emphysematous lung. Fetal lung tissue from green fluorescent protein C57BL/6 mice at 16 days' gestation was used as donor material. Twelve-month-old pallid mice were used as recipients. Donor lungs were cut into small pieces and implanted into the recipient left lung by performing thoracotomy under anesthesia. The recipient mice were sacrificed at day 7, 14, and 28 after implantation and used for histological examination. Well-developed spontaneous pulmonary emphysema was seen in 12-month-old pallid mice. Smooth and continuous connection between implanted fetal lung tissue and recipient lung was recognized. Air space expansion and donor tissue differentiation were observed over time. We could clearly distinguish the border zones between injected tissue and native tissue by the green fluorescence of grafts. Fetal mouse lung fragments survived and differentiated in the emphysematous lung of pallid mice. Implantation of fetal lung tissue in pallid mice might lead to further lung regeneration research from the perspective of respiratory and exercise function. J. Med. Invest. 63: 182-186, August, 2016. (Tokushima University Institutional Repository) ● Metadata: 111178 (Link to Publication Site) ● Publication site (DOI): 10.2152/jmi.63.182 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 27644555 ● Summary page in Scopus @ Elsevier: 2-s2.0-84987925398 (Tokushima University Institutional Repository: 111178, DOI: 10.2152/jmi.63.182, PubMed: 27644555, Elsevier: Scopus)
92.	Hiroaki Toba, Koichiro Kenzaki, Hiromitsu Takizawa, Shoji Sakiyama, Kazuya Kondo and Akira Tangoku : 急速に増大する巨大気腫性肺囊胞に対して囊胞内吸引後にEWSとフィブリン糊注入で軽快した1例, The Journal of the Japan Society for Respiratory Endoscopy, Vol.38, No.4, 324-327, 2016. (Link to Publication Site) ● Publication site (DOI): 10.18907/jjsre.38.4_324 (Link to Search Site for Scientific Articles) ● Search Scopus @ Elsevier (DOI): 10.18907/jjsre.38.4_324 (DOI: 10.18907/jjsre.38.4_324)
93.	Hiromitsu Takizawa, Mitsuhiro Tsuboi, Koichiro Kajiura, Hiroaki Toba, Yasushi Nakagawa, Yukikiyo Kawakami, Mitsuteru Yoshida, Shoji Sakiyama, Kazuya Kondo and Akira Tangoku : 胸腔鏡下右上葉切除術の手術時間に影響する因子の検討, The Journal of the Japanese Association for Chest Surgery, Vol.30, No.1, 2-7, 2016. (Link to Publication Site) ● Publication site (DOI): 10.2995/jacsurg.30.2 (Link to Search Site for Scientific Articles) ● Search Scopus @ Elsevier (DOI): 10.2995/jacsurg.30.2 (DOI: 10.2995/jacsurg.30.2)
94.	松本大資, Hiromitsu Takizawa, 高嶋美佳, Yukikiyo Kawakami, Kazuya Kondo and Akira Tangoku : Chest Wall Metastasis of Anaplastic Lymphoma Kinase-positive Lung Adenocarcinoma 22 Years After Lobectomy, Japanese Journal of Lung Cancer, Vol.56, No.7, 1046-1050, 2016. (Summary) <p><b><i>Background. </i></b>When a new tumor appears after a long period of remission following surgery for lung cancer, it is difficult to determine whether the tumor is a recurrence or a new tumor. We herein report a case of a chest wall tumor that developed 22 years after pulmonary lobectomy diagnosed by an anaplastic lymphoma kinase (ALK) gene mutation. <b><i>Case. </i></b>An 80-year-old man underwent left-lung upper lobectomy for lung adenocarcinoma (pT4N2M0 Stage III) 22 years prior. We treated him with adjuvant chemotherapy after the surgery and did not detect a recurrence for 10 years. However, we noticed a chest wall mass 22 years after the surgery and diagnosed it by a biopsy as adenocarcinoma. The new specimen was stained with anti-thyroid transcription factor-1 (TTF-1) and anti-ALK antibodies, and the pathological specimen from the first surgery was also stained with anti-ALK antibody. We therefore diagnosed the chest wall tumor as a recurrence of the lung adenocarcinoma. We treated him with crizotinib, and the tumor shrank. However, we stopped the treatment because of the development of drug-induced interstitial pneumonia. We switched him to a platinum combination regimen, and follow-up is ongoing. <b><i>Conclusions. </i></b>When a lesion is suspected to be a recurrence long after surgery, an examination of gene mutations, such as that of ALK, may be useful.</p> (Keyword) Lung cancer / ALK / Late recurrence (Link to Publication Site) ● Publication site (DOI): 10.2482/haigan.56.1046 (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1390001204683808512 ● Search Scopus @ Elsevier (DOI): 10.2482/haigan.56.1046 (DOI: 10.2482/haigan.56.1046, CiNii: 1390001204683808512)
95.	Hiroaki Toba, Shoji Sakiyama, Hiromitsu Takizawa and Akira Tangoku : Safe and successful treatment with afatinib in three postoperative non-small cell lung cancer patients with recurrences following gefitinib/erlotinib-induced hepatotoxicity., The Journal of Medical Investigation : JMI, Vol.63, No.1-2, 149-151, 2016. (Summary) Afatinib could be a well-tolerated EGFR-TKI that could be chosen for its relatively low hepatotoxicity, which is attributable to its having a different metabolic mechanism compared to other EGFR-TKIs. J. Med. Invest. 63: 149-151, February, 2016. (Tokushima University Institutional Repository) ● Metadata: 111176 (Link to Publication Site) ● Publication site (DOI): 10.2152/jmi.63.149 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 27040072 ● Summary page in Scopus @ Elsevier: 2-s2.0-84962204130 (Tokushima University Institutional Repository: 111176, DOI: 10.2152/jmi.63.149, PubMed: 27040072, Elsevier: Scopus)
96.	Mitsuhiro Tsuboi, 松本大資, 河北直也, Koichiro Kajiura, Hiroaki Toba, Yasushi Nakagawa, Yukikiyo Kawakami, Hiromitsu Takizawa, Shoji Sakiyama, Kazuya Kondo and Akira Tangoku : Acute exacerbation of interstitial pneumonia after pulmonary resection for lung cancer : Analysis of two cases, Shikoku Acta Medica, Vol.71, No.3,4, 81-86, 2015. (Summary) Acute exacerbation of interstitial pneumonia (IP) is one of the most severe and fatal postoperative complications in lung cancer patients underlying IP. We treated two patients suffered from acute exacerbation of IP after pulmonary resection for lung cancer. We analyzed their clinical findings. Thoracoscopic lobectomy with mediastinal lymph node dissection was performed in these cases. The patients were diagnosed with acute exacerbation 4 or 5 days after operation and treated with steroids. Both patients had not been diagnosed as IPs before surgery, however, IPs were diagnosed by retrospective analysis of pathological examination for the removal lungs. Chest CT before surgery showed an interstitial shadow in the lung field faintly in these cases. It should be considered that patients who show a faint interstitial shadow in chest CT could potentially cause an acute exacerbation of IP after lung cancer operation. (Keyword) lung cancer / interstitial pneumonia / acute exacerbation (Tokushima University Institutional Repository) ● Metadata: 109923 (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1050564287688057600 (Tokushima University Institutional Repository: 109923, CiNii: 1050564287688057600)
97.	Tamaki Otani, Hideki Otsuka, Kazuya Kondo, Hiromitsu Takizawa, Motoi Nagata, Mina Kishida and Hirokazu Miyoshi : Utility of respiratory-gated small-animal PET/CT in the chronologic evaluation of an orthotopic lung cancer transplantation mouse model., Radiological Physics and Technology, Vol.8, No.2, 266-277, 2015. (Summary) Our aim in this study was to clarify the effects of respiratory-gated PET in the evaluation of lung cancer according to the (18)F-FDG uptake in an orthotopic transplantation mouse model. We created such a model, and we performed PET/CT. The mice were divided into two groups according to tumor volume: a small-tumor group (<20 mm(3)) and a large-tumor group (>20 mm(3)). We reconstructed the following conditions based on list-mode data: non-gated (3D) images and gated (4D) images, divided based on the respiratory cycle (expiration phase, stable phase, and inspiration phase). We calculated the maximum standardized uptake values (SUVmax) in each phase. We used the % difference [= (4D SUVmax - 3D SUVmax)/3D PET SUVmax × 100 (%)] to evaluate the differences in the 4D SUVmax and 3D SUVmax. The 4D SUVmax values were significantly higher than the 3D SUVmax, regardless of the tumor size. The % difference for the small tumors was greater than that for the large tumors, and it was highest in the stable phase. We conclude that the SUVmax in the stable phase under respiratory-gated PET are the most reliable. The SUVmax observed under non-gated PET are considered to be more frequently underestimated in cases involving small tumors than in those involving large tumors. In the chronologic study evaluating the time course of tumor development, the size of the tumor is small in early stage, and respiratory-gated PET is effective in reducing the underestimation of such tumors caused by respiratory motion. (Tokushima University Institutional Repository) ● Metadata: 109701 (Link to Publication Site) ● Publication site (DOI): 10.1007/s12194-015-0316-3 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 25921487 ● Summary page in Scopus @ Elsevier: 2-s2.0-84937518832 (Tokushima University Institutional Repository: 109701, DOI: 10.1007/s12194-015-0316-3, PubMed: 25921487, Elsevier: Scopus)
98.	Hiromitsu Takizawa, Hirokazu Takechi, 坂本晋一, 住友弘幸, Mitsuhiro Tsuboi, Yasushi Nakagawa and Akira Tangoku : 甲状腺未分化癌に対するsorafenibによる治療経験, Official Journal of the Japan Association of Endocrine Surgeons and the Japanese Society of Thyroid Surgery, Vol.32, No.1, 49-52, 2015. (Link to Publication Site) ● Publication site (DOI): 10.11226/jaesjsts.32.1_49 (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1390001205427058176 ● Search Scopus @ Elsevier (DOI): 10.11226/jaesjsts.32.1_49 (DOI: 10.11226/jaesjsts.32.1_49, CiNii: 1390001205427058176)
99.	Koichiro Kajiura, Hiromitsu Takizawa, Mitsuhiro Tsuboi, Hiroaki Toba, Yasushi Nakagawa, Yukikiyo Kawakami, Shoji Sakiyama, Kazuya Kondo and Akira Tangoku : 人工呼吸器管理中の慢性有瘻性膿胸に対してEWSを用いた気管支充填術を施行した1例, The Journal of the Japan Society for Respiratory Endoscopy, Vol.37, No.4, 409-413, 2015. (Link to Publication Site) ● Publication site (DOI): 10.18907/jjsre.37.4_409 (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1390282679731563264 ● Search Scopus @ Elsevier (DOI): 10.18907/jjsre.37.4_409 (DOI: 10.18907/jjsre.37.4_409, CiNii: 1390282679731563264)
100.	Hiromitsu Takizawa, Mitsuhiro Tsuboi, Koichiro Kajiura, Hiroaki Toba, Yasushi Nakagawa, Yukikiyo Kawakami, Mitsuteru Yoshida, Shoji Sakiyama, Kazuya Kondo, 森下敦司, 河北直也 and 広瀬敏幸 : 肺癌の術中胸膜浸潤診断の正確性についての検討, The Journal of the Japanese Association for Chest Surgery, Vol.29, No.5, 576-581, 2015. (Link to Publication Site) ● Publication site (DOI): 10.2995/jacsurg.29.576 (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1390001204361159936 ● Search Scopus @ Elsevier (DOI): 10.2995/jacsurg.29.576 (DOI: 10.2995/jacsurg.29.576, CiNii: 1390001204361159936)
101.	Hisashi Matsuoka, Kazuya Kondo, Hiromitsu Takizawa, Haruhiko Fujino, Etsuko Sakamoto, Junji Uchida, Koh Uyama, Hiroaki Toba, Koichiro Kenzaki, Shoji Sakiyama and Akira Tangoku : Comprehensive evaluation of the response of genes to the administration of the antitumor drug S-1 using a low density array., International Journal of Oncology, Vol.46, No.2, 569-577, 2014. (Summary) S-1 is a newly developed dihydropyrimidine dehydrogenase inhibitory fluoropyrimidine that exhibits high clinical efficacy against non-small cell lung cancers. To identify genes that may be associated with chemosensitivity to the antitumor drug S-1, we used a low density array representing 93 genes to analyze expression profiles in 4 orthotopically implanted lung cancers derived from human lung cancer cell lines (Lu99, Lu130, LC6 and A549). The tumor growth inhibition (TGI) rates of S-1 in orthotopically implanted tumors of the Lu99, Lu130, LC6 and A549 cell lines were 34.6, 37.5, 32.1 and 3.6%, respectively. The expression of the PRSS3, ABCC4, TXN, SHMT1 and CMPK genes was significantly promoted in the orthotopically implanted SCID mouse model of the 4 lung cancer cell lines by the administration of S-1, while the expression of the LMO7 and FOLH1 genes was significantly suppressed. The expression of the ABCC1, 2 and TST genes was negatively correlated with TGI. The expression of the TK1 and ERCC2 genes was positively correlated with TGI. The results of the present study suggest that the expression of the ABCC1, 2, TST, TK1 and ERCC2 genes is related to resistance to the antitumor drug S-1. (Keyword) Animals / Antineoplastic Agents / Cell Line, Tumor / Drug Combinations / Gene Expression Regulation, Neoplastic / Humans / Lung Neoplasms / Mice / Microarray Analysis / Neoplasm Proteins / Oxonic Acid / Tegafur / Xenograft Model Antitumor Assays (Tokushima University Institutional Repository) ● Metadata: 106443 (Link to Publication Site) ● Publication site (DOI): 10.3892/ijo.2014.2754 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 25405593 ● Summary page in Scopus @ Elsevier: 2-s2.0-84918509235 (Tokushima University Institutional Repository: 106443, DOI: 10.3892/ijo.2014.2754, PubMed: 25405593, Elsevier: Scopus)
102.	Khalil Abdellah Hamed Ali, Hiroaki Toba, Shoji Sakiyama, Ryo Yamamoto, Hiromitsu Takizawa, Koichiro Kenzaki, Kazuya Kondo and Akira Tangoku : Holter ECG monitoring of sympathovagal fluctuation during bronchoscopy., The Clinical Respiratory Journal, 2014. (Summary) This study shows for the first time that Holter ECG monitoring during diagnostic bronchoscopy was associated with activation of cardiac sympathetic and withdrawal of cardiac parasympathetic regulation, which may contribute to the occurrence of cardiac events during bronchoscopic procedures. So, Holter ECG monitoring during bronchoscopic procedures may confer reduction in cardiovascular events. (Keyword) ECG / bronchoscopy (Link to Publication Site) ● Publication site (DOI): 10.1111/crj.12204 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 25195956 ● Search Scopus @ Elsevier (PMID): 25195956 ● Search Scopus @ Elsevier (DOI): 10.1111/crj.12204 (DOI: 10.1111/crj.12204, PubMed: 25195956)
103.	Mitsuhiro Tsuboi, Shoji Sakiyama, 住友弘幸, 坂本晋一, Koichiro Kajiura, Hiroaki Toba, Yasushi Nakagawa, Yukikiyo Kawakami, Hiromitsu Takizawa, Kazuya Kondo and Akira Tangoku : Evaluation of Powered ECHELON FLEX for pulmonary lobectomy, Shikoku Acta Medica, Vol.70, No.3-4, 57-60, 2014. (Summary) Objective : It has been accepted to use staplers for open and video-assisted thoracic surgery, however there was a risk in stapling of the pulmonary vasculatures. A newly developed stapler, powered ECHELON FLEX (Ethicon) is an electrically-powered stapler. It may reduce tip movement during cutting and stapling, which results in reduction of the risk of trauma to surrounding tissue. The aim of this study was to evaluate powered ECHELON FLEX for pulmonary lobectomy. Methods : We reviewed 16 patients who underwent pulmonary lobectomy with powered ECHELON FLEX in our institution from December, 2013 to April, 2014. Results : There were 25 stapling for the pulmonary artery, 17 stapling for the pulmonary vein, 16 stapling for the bronchus, and 33 stapling for the pulmonary parenchyma. Though two case of oozing from the stamps of a pulmonary artery and pulmonary parenchyma, there were no serious complications related to use of the staplers. Conclusions : The powered ECHELON FLEX can be used for pulmonary lobectomy safely. (Keyword) pulmonary lobectomy / powered stapler (Tokushima University Institutional Repository) ● Metadata: 109754 (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1050845762395123840 (Tokushima University Institutional Repository: 109754, CiNii: 1050845762395123840)
104.	Hiromitsu Takizawa, Shoji Sakiyama, Koichiro Kajiura, 森下敦司, 西野豪志, Mitsuhiro Tsuboi, Hiroaki Toba, Yasushi Nakagawa, Mitsuteru Yoshida, Yukikiyo Kawakami, Kazuya Kondo and Akira Tangoku : Setting of fees for robotic surgery for lung cancer not covered by insurance, Shikoku Acta Medica, Vol.70, No.3,4, 51-56, 2014. (Summary) In Japan, the only robot surgery covered by health insurance is prostatectomy. Robot surgery for pulmonary cancer has not been approved as advanced health care, and hospitals are required to set out-of-pocket fees for surgery on their own. We calculated the fee not covered by insurance to be 1.28million yen, taking into account expenses for : (1) the use of medical equipment, (2) maintenance, (3) labor costs, and (4) medical materials and drugs. Since the fees for surgery plus hospitalization are actually incurred by patients, whether or not the hospitalization fee should be included in out-of-pocket medical fees is decided by each health care institution. In any case, it is necessary to provide patients with a summary of medical fees prior to surgery. Hospitals are required to collect data on pulmonary robot surgical cases while operating the system with medical fees incurred by individual patients. (Keyword) lung cancer / robotic surgery / surgical fee (Tokushima University Institutional Repository) ● Metadata: 109753 (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1050564287418413056 (Tokushima University Institutional Repository: 109753, CiNii: 1050564287418413056)
105.	Hiromitsu Takizawa and Shoji Sakiyama : [Sentinel node identification of lung cancer]., The Japanese Journal of Thoracic Surgery, Vol.67, No.8, 753-757, 2014. (Summary) Sentinel node identification is important for small-sized non small cell lung cancer patients who are candidates for segmentectomy in determining their eligibilities. Intraoperative sentinel node identification using indocyanine green or preoperative computed tomography lymphography by transbronchial injection of iopamidol are suitable for daily medical practices, because these methods take about only 10 minutes to identify sentinel nodes in addition to routine surgical or bronchoscopic procedures. (Keyword) Bronchi / Contrast Media / Humans / Indocyanine Green / Intraoperative Period / Iopamidol / Lung Neoplasms / Lymph Nodes / Lymphatic Metastasis / Lymphography / Sentinel Lymph Node Biopsy / Tomography, X-Ray Computed (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 25138951 ● Search Scopus @ Elsevier (PMID): 25138951 (PubMed: 25138951)
106.	Hiromitsu Takizawa, Shoji Sakiyama, Akira Tangoku, Koichiro Kajiura and Hiroaki Toba : 肺癌におけるsentinel node navigation surgery, Surgery, Vol.76, No.4, 371-376, 2014. (Keyword) 肺癌 / センチネルリンパ節 / ナビゲーション手術 (Link to Publication Site) ● Publication site (DOI): 10.15106/j00393.2014127367 (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1390001288081481984 ● Search Scopus @ Elsevier (DOI): 10.15106/j00393.2014127367 (DOI: 10.15106/j00393.2014127367, CiNii: 1390001288081481984)
107.	Hiromitsu Takizawa, Akira Tangoku, Shoji Sakiyama, Koichiro Kajiura, 森下敦司, Mitsuhiro Tsuboi, Hiroaki Toba, Yasushi Nakagawa, Mitsuteru Yoshida, Yukikiyo Kawakami and Kazuya Kondo : 特集:Sentinel node navigation surgery Ⅱ．各論 3．肺癌におけるsentinel node navigation surgery, Clinical Orthopaedic Surgery, Vol.76, No.4, 371-376, 2014. (Link to Publication Site) ● Publication site (DOI): 10.15106/J00393.2014127367 (Link to Search Site for Scientific Articles) ● Search Scopus @ Elsevier (DOI): 10.15106/J00393.2014127367 (DOI: 10.15106/J00393.2014127367)
108.	Mohamed Mokhtar, Kazuya Kondo, Hiromitsu Takizawa, Tamaki Otani, Hideki Otsuka, Hitoshi Kubo, Koichiro Kajiura, Yasushi Nakagawa, Yukikiyo Kawakami, Mitsuteru Yoshida, Haruhiko Fujino, Shoji Sakiyama and Akira Tangoku : Non-invasive monitoring of anticancer effects of cisplatin on lung cancer in an orthotopic SCID mouse model using [¹⁸F] FDG PET-CT., Oncology Reports, Vol.31, No.5, 2007-2014, 2014. (Summary) Positron emission tomography-computed tomography (PET-CT) with [18F] fluorodeoxyglucose (FDG) has recently been applied for evaluating tumor response to anticancer therapy. The aim of the present study was to evaluate the utility of FDG PET-CT in monitoring non-invasively and repeatedly the inhibitory effect of cisplatin (CDDP) on an orthotopic lung cancer model. Validation of in vivo FDG uptake in human lung cancer Ma44-3 cell line in an orthotopic SCID mouse model was carried out. Next, we assessed the use of FDG PET-CT to monitor the response of orthotopic lung cancer to the anticancer effect of CDDP. SCID mice were divided into the CDDP group (7 mg/kg single dose intraperitoneally) and the control group. Tumor volume and maximal standardized uptake value (SUV max) were calculated for all mice. All mice were sacrificed for histopathologic analysis. Validation of FDG PET-CT showed that tumor volume and SUV max were significantly correlated with postmortem tumor length measured in specimens (P=0.023) and (P=0.012), respectively, and there was a significant correlation between SUV max and tumor volume (P=0.048). Response monitoring showed that significant growth inhibition by CDDP in the form of SUV max of the CDDP group was significantly lower than that of the control group on day 8 (P=0.02) and on day 13 (P=0.003). Tumor volume of the CDDP group was significantly lower than that of the control group on day 13 (P=0.03). The present study supports using FDG PET-CT in monitoring tumor progression and therapeutic response of lung cancer in an orthotopic model non‑invasively and repeatedly. (Link to Publication Site) ● Publication site (DOI): 10.3892/or.2014.3056 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 24604559 ● Summary page in Scopus @ Elsevier: 2-s2.0-84898640682 (DOI: 10.3892/or.2014.3056, PubMed: 24604559, Elsevier: Scopus)
109.	Mohamed Mokhtar, Kazuya Kondo, Toshiaki Namura, Abdellah H.K. Ali, Yui Fujita, Chikako Takai, Hiromitsu Takizawa, Yasushi Nakagawa, Hiroaki Toba, Koichiro Kajiura, Mitsuteru Yoshida, Yukikiyo Kawakami, Shoji Sakiyama and Akira Tangoku : Methylation and expression profiles of MGMT gene in thymic epithelial tumors, Lung Cancer, Vol.83, No.2, 279-287, 2014. (Summary) A key challenge in diagnosis and treatment of thymic epithelial tumors (TET) is in improving our understanding of the genetic and epigenetic changes of these relatively rare tumors. Methylation specific PCR (MSP) and immunohistochemistry were applied to 66 TET to profile the methylation status of DNA repair gene O6-methylguanine DNA methyltransferase (MGMT) and its protein expression in TET to clarify the association between MGMT status and clinicopathological features, response to chemotherapy and overall survival. MGMT methylation was significantly more frequent in thymic carcinoma than in thymoma (17/23, 74% versus 13/44, 29%; P<0.001). Loss of expression of MGMT protein was significantly more frequent in thymic carcinoma than in thymoma (20/23, 87% versus 10/44, 23%; P<0.0001). There is a significant correlation between of MGMT methylation and loss of its protein expression (P<0.0003). MGMT methylation and loss of expression were significantly more frequent in advanced thymic epithelial tumors (III/IV) than in early tumors (I/II). MGMT methylation plays a soul role in development of TET, especially in thymic carcinoma. Therefore, translation of our results from basic molecular research to clinical practice may have important implication for considering MGMT methylation as a marker and a target of future therapies in TET. (Keyword) Adult / Aged / carcinogenesis / Carcinoma / DNA Methylation / DNA Modification Methylases / DNA Repair Enzymes / Epigenesis, Genetic / Humans / Male / Middle Aged / Neoplasm Staging / Neoplasms, Glandular and Epithelial / Promoter Regions, Genetic / Thymoma / Thymus Neoplasms / Tumor Suppressor Proteins (Tokushima University Institutional Repository) ● Metadata: 106223 (Link to Publication Site) ● Publication site (DOI): 10.1016/j.lungcan.2013.12.004 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 24388682 ● Summary page in Scopus @ Elsevier: 2-s2.0-84892877225 (Tokushima University Institutional Repository: 106223, DOI: 10.1016/j.lungcan.2013.12.004, PubMed: 24388682, Elsevier: Scopus)
110.	Hiromitsu Takizawa, Shoji Sakiyama, Mitsuhiro Tsuboi and Akira Tangoku : Demonstration of the skip metastasis pathway for N2 non-small cell lung cancer., Journal of Thoracic and Cardiovascular Surgery, Vol.147, No.4, e50-2, 2014. (Keyword) Aged / Carcinoma, Non-Small-Cell Lung / Female / Humans / Lung Neoplasms / Lymphatic Metastasis / Neoplasm Staging (Link to Publication Site) ● Publication site (DOI): 10.1016/j.jtcvs.2013.12.058 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 24518224 ● Summary page in Scopus @ Elsevier: 2-s2.0-84896506910 (DOI: 10.1016/j.jtcvs.2013.12.058, PubMed: 24518224, Elsevier: Scopus)
111.	Masakazu Goto, Akira Tangoku, Hiromitsu Takizawa, Hirokazu Takechi and Yoshihito Furukita : Usefulness of lymphangiography with near infrared fluorescence system in treatment of postoperative chylothorax, Surgery, Vol.76, No.1, 64-67, 2014. (Keyword) 乳び胸 / リンパ管造影 / indocyanine green (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1390282763058189568 (CiNii: 1390282763058189568)
112.	Takeshi Nishino, Hiromitsu Takizawa, Mitsuteru Yoshida, Yukikiyo Kawakami, Shoji Sakiyama and Kazuya Kondo : 進行肺癌に合併した続発性気胸に対する胸腔内フィブリン糊注入療法の経験, The Journal of the Japanese Association for Chest Surgery, Vol.28, No.1, 13-18, 2014. (Link to Publication Site) ● Publication site (DOI): 10.2995/jacsurg.28.13 (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1390001204361276800 ● Search Scopus @ Elsevier (DOI): 10.2995/jacsurg.28.13 (DOI: 10.2995/jacsurg.28.13, CiNii: 1390001204361276800)
113.	Hirokazu Takechi, Kazuaki Mawatari, Nagakatsu Harada, Yutaka Nakaya, Megumi Asakura, Mutsumi Aihara, Hiromitsu Takizawa, Masakazu Goto, Takeshi Nishino, Takuya Minato, Yoshihito Furukita, Yota Yamamoto, Yasuhiro Yuasa, Hiromichi Yamai, Takahiro Yoshida, Jun-ichi Seike and Akira Tangoku : Glutamine protects the small intestinal mucosa in anticancer drug-induced rat enteritis model., The Journal of Medical Investigation : JMI, Vol.61, No.1-2, 59-64, 2014. (Summary) Supportive therapy during chemotherapy has become essential, but effective preventive therapies to gastrointestinal mucosal injury are few. We investigated the efficacy of glutamine in rat anticancer drug-induced enteritis model. In this study, we used twenty male SD rats. They were divided into control, 5-fluorouracil (5-FU) (orally administered at 20 mg/kg day), 5-FU+glutamine (1000 mg/kg/day) and 5-FU+glutamine+fiber and oligosaccharide (GFO(®)) (1000 mg/kg/day) groups. All groups were sacrificed on day 6 and upper jejunums were excised. The jejunal villous height was measured in specimens. IgA level in jejunal washing solution, and serum diamine oxidase activity were also measured. The jejunal villous height was recognized as shorter in the specimen from 5-FU treated rats compared with 5-FU+glutamine treated rats (p<0.001). Serum diamine oxidase activity in 5-FU+glutamine group were significantly superior to that in 5-FU group (p=0.028). IgA level in jejunal washing solution tended to be higher in 5-FU+glutamine group than that in 5-FU group (p=0.076). On the other hand, serum diamine oxidase activity and IgA level in jejunal washing solution showed no significant difference between 5-FU+GFO and 5-FU treatment group. Our results suggest that glutamine showed protective effects on mucosal injury of small intestine in rat anticancer drug-induced enteritis model. (Keyword) glutamine / gastrointestinal toxity / anticancer drug / diamine oxidase / IgA (Tokushima University Institutional Repository) ● Metadata: 109521 (Link to Publication Site) ● Publication site (DOI): 10.2152/jmi.61.59 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 24705750 ● CiNii @ National Institute of Informatics (CRID): 1390001204244693120 ● Summary page in Scopus @ Elsevier: 2-s2.0-84897937797 (Tokushima University Institutional Repository: 109521, DOI: 10.2152/jmi.61.59, PubMed: 24705750, CiNii: 1390001204244693120, Elsevier: Scopus)
114.	Khasag Narmisheekh, Shoji Sakiyama, Hiroaki Toba, Mitsuteru Yoshida, Yasushi Nakagawa, Hiromitsu Takizawa, Yukikiyo Kawakami, Koichiro Kenzaki, Ali Hamed Khalil Abdellah, Kazuya Kondo and Akira Tangoku : Monitoring of exhaled carbon monoxide and carbon dioxide during lung cancer operation, European Journal of Cardio-Thoracic Surgery, Vol.45, No.3, 531-536, 2013. (Summary) Carbon monoxide (CO) is expelled mainly via the lungs, so that exhaled carbon monoxide (Ex-CO) concentration reflects endogenous production. Recent reports have shown that Ex-CO levels are increased in critically ill patients and after anaesthesia and surgery. However, there has been no investigation of the changes in Ex-CO level during a lung operation. We continuously monitored Ex-CO and exhaled carbon dioxide (Ex-CO2) concentrations during surgery for lung cancer. Eighteen lung cancer patients who underwent elective lung cancer lobectomy were enrolled in this study. All patients were endotracheally intubated and ventilated under general anaesthesia. Ex-CO and Ex-CO2 concentrations were separately monitored and recorded continuously using two sets of Carbolyzer® breath analysers (Taiyo Inc., Osaka, Japan). Ex-CO concentration increased rapidly in response to changes in body position from supine to decubitus and was significantly decreased when patients were once again lying back (supine 2). Upon restarting bilateral ventilation, Ex-CO concentration in the operated lung was significantly higher than that in the breathing lung. In the lateral decubitus position, Ex-CO2 concentration showed the same pattern of increase as seen for Ex-CO. In the operated lung, the Ex-CO2 concentrations changed significantly at clamping, declamping and supine 2. In the re-ventilated, operated lung, the Ex-CO2 concentration was significantly lower than in the breathing lung. In the breathing lung, the Ex-CO2 concentration did not exhibit any significant changes over the course of the operation. When breathing was restarted, the Ex-CO level of the target lung was significantly higher than that of the breathing lung. The Ex-CO concentration was also affected by the surgical body position and this change was marked and transient. (Keyword) Aged / carbon dioxide / Carbon Monoxide / Exhalation / Female / Humans / Lung Neoplasms / Male / Middle Aged / Monitoring, Physiologic / Respiration, Artificial (Tokushima University Institutional Repository) ● Metadata: 105937 (Link to Publication Site) ● Publication site (DOI): 10.1093/ejcts/ezt395 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 23913245 ● Summary page in Scopus @ Elsevier: 2-s2.0-84894341845 (Tokushima University Institutional Repository: 105937, DOI: 10.1093/ejcts/ezt395, PubMed: 23913245, Elsevier: Scopus)
115.	Hiroaki Toba, Kazuya Kondo, Yohei Sadohara, Hideki Otsuka, Masami Morimoto, Koichiro Kajiura, Yasushi Nakagawa, Mitsuteru Yoshida, Yukikiyo Kawakami, Hiromitsu Takizawa, Koichiro Kenzaki, Shoji Sakiyama, Yoshimi Bando and Akira Tangoku : 18F-fluorodeoxyglucose positron emission tomography/computed tomography and the relationship between fluorodeoxyglucose uptake and the expression of hypoxia-inducible factor-1, glucose transporter-1 and vascular endothelial growth factor in thymic epithelial tumours., European Journal of Cardio-Thoracic Surgery, Vol.44, No.2, e105-e112, 2013. (Summary) OBJECTIVES: The objective of this study was to evaluate the usefulness of (18)F-fluorodeoxyglucose positron emission tomography/computed tomography (FDG-PET/CT) and the relationships among the expressions of hypoxia-inducible factor-1 (HIF-1), glucose transporter-1 (Glut-1) and vascular endothelial growth factor (VEGF), histological type, other clinical factors and FDG uptake in thymic epithelial tumours. METHODS: Thirty-three patients who underwent FDG-PET/CT before treatment were reviewed. All types of tumours were reclassified into three subgroups: low-risk thymomas (types A, AB and B1), high-risk thymomas (types B2 and B3) and thymic carcinomas. Tumour contour, pattern of FDG uptake, tumour size and maximum standardized uptake value (SUVmax) were obtained. Expressions of HIF-1, Glut-1 and VEGF were analysed immunohistochemically, and these expressions were evaluated using grading scales. RESULTS: FDG uptake was visually recognized in all (100%) tumours. A homogeneous pattern of FDG uptake was increasingly observed in the order of low-risk thymomas to high-risk thymomas to thymic carcinomas (P = 0.016). SUVmax for thymic carcinomas was significantly higher than that for thymomas (P = 0.008). With the optimal cut-off value of SUVmax of 5.6, the sensitivity, specificity and accuracy for diagnosing thymic carcinoma were 0.75, 0.80 and 0.79, respectively. Regarding the mean scoring of HIF-1, Glut-1 and VEGF, increasing trends were observed in the order of low-risk thymomas to high-risk thymomas to thymic carcinomas. Tumour size revealed a significant correlation with SUVmax (r = 0.60, P < 0.001), and the expression of HIF-1 showed a moderate association, but the expression of Glut-1 showed no correlation with SUVmax. Regarding correlations between the expression of the three markers, there were moderate associations between HIF-1 and Glut-1, and HIF-1 and VEGF, and a significant correlation between Glut-1 and VEGF (r = 0.60, P < 0.001). In type B1 thymoma, HIF-1 and Glut-1 were partly expressed in non-neoplastic immature lymphocytes. CONCLUSIONS: FDG-PET/CT should be performed in patients with tumours in the anterior mediastinum because the pattern of FDG uptake and SUVmax are useful in the differential diagnosis of thymic epithelial tumours. Furthermore, the expressions of HIF-1, Glut-1 and VEGF might be associated with malignancy of thymic epithelial tumours. In contrast, FDG uptake might be dependent on tumour size rather than Glut-1 overexpression. (Link to Publication Site) ● Publication site (DOI): 10.1093/ejcts/ezt263 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 23674658 ● Search Scopus @ Elsevier (PMID): 23674658 ● Search Scopus @ Elsevier (DOI): 10.1093/ejcts/ezt263 (DOI: 10.1093/ejcts/ezt263, PubMed: 23674658)
116.	Hiroaki Toba, Kazuya Kondo, Takanori Miyoshi, Koichiro Kajiura, Mitsuteru Yoshida, Yukikiyo Kawakami, Hiromitsu Takizawa, Koichiro Kenzaki, Shoji Sakiyama and Akira Tangoku : Fluoroscopy-assisted thoracoscopic resection after computed tomography-guided bronchoscopic metallic coil marking for small peripheral pulmonary lesions., European Journal of Cardio-Thoracic Surgery, 2013. (Summary) OBJECTIVES: To re-evaluate the efficacy of fluoroscopy-assisted thoracoscopic resection after computed tomography (CT)-guided bronchoscopic metallic coil marking (FATS-CM), which was our original method for small peripheral pulmonary lesions. METHODS: Fifty-eight patients with 63 lesions underwent FATS-CM. A metallic coil was installed in the bronchus nearest to the lesion under CT fluoroscopic guidance with ultrathin bronchoscopy. The virtual bronchoscopic navigation (VBN) system was used in 14 cases. Afterwards, we basically performed wide wedge resection (WWR) using a C-arm-shaped roentgenographic fluoroscope during thoracoscopic surgery initially, and then the final procedure was determined by intraoperative histological diagnosis. Moreover, we prospectively treated ground-glass opacity (GGO) lesions of <20 mm diameter according to our treatment protocol from September 2004. RESULTS: We could install coils in the objective bronchi in all cases. The average time required for the marking procedure was 38.9 (15-120) min. Pneumothorax was recognized in 1 (1.7%) case as a complication, but no fatal complications occurred. We could also install coils for each lesion in 4 cases (9 lesions) with multiple lesions. In 14 cases with the VBN system, the examination time and CT number were significantly reduced (P < 0.05 and <0.001, respectively), compared with those of 40 cases without the VBN system. The average interval between the CM and the operation was 5.6 (0-30) days. We never experienced a case of migration preoperatively. Sixty-two (98.4%) lesions were definitively identified, and WWRs were performed using three trocars in 58 (92.1%) cases during thoracoscopic surgery. Lobectomy was initially performed in only 1 case owing to coil migration. Thirty-seven of 40 cases (92.5%) were in line with the treatment protocol. There were no local-regional recurrences in all cases undergoing WWR. CONCLUSIONS: We could prospectively show that our method was suitable to perform WWR with a sufficient margin for small GGO lesions of <20 mm. Moreover, we reconfirmed that the advantages of our method were safety, permitting flexibility in scheduling operations and a high ability to deal with multiple lesions. Additionally, our method became a minimally invasive and mature technique by using a new VBN system. (Link to Publication Site) ● Publication site (DOI): 10.1093/ejcts/ezt220 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 23598353 ● Search Scopus @ Elsevier (PMID): 23598353 ● Search Scopus @ Elsevier (DOI): 10.1093/ejcts/ezt220 (DOI: 10.1093/ejcts/ezt220, PubMed: 23598353)
117.	Seiya Inoue, Hiromitsu Takizawa, Yota Yamamoto and Akira Tangoku : Therapeutic hypothermia for severe cerebral air embolism complicating pleural lavage for empyema., Interactive Cardiovascular and Thoracic Surgery, Vol.17, No.1, 199-201, 2013. (Summary) Cerebral air embolism during pleural lavage is a rare, but potentially fatal complication. We present a case of severe cerebral air embolism that developed during pleural lavage for empyema and was successfully treated by therapeutic hypothermia. A 77-year old male patient with empyema developed severe cerebral air embolism during pleural lavage via a chest tube. Cranial computed tomography and cranial magnetic resonance imaging showed many small bubbles and widespread infarction in the territory of the right middle cerebral artery. The patient received therapeutic hypothermia maintained at 33°C for 24 h and could leave the hospital without delayed sequelae. (Keyword) Aged / Cerebral Angiography / Diffusion Magnetic Resonance Imaging / Embolism, Air / Empyema, Pleural / Humans / Hypothermia, Induced / Intracranial Embolism / Magnetic Resonance Angiography / Male / Therapeutic Irrigation / Tomography, X-Ray Computed / Treatment Outcome (Link to Publication Site) ● Publication site (DOI): 10.1093/icvts/ivt129 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 23575752 ● Summary page in Scopus @ Elsevier: 2-s2.0-84879487956 (DOI: 10.1093/icvts/ivt129, PubMed: 23575752, Elsevier: Scopus)
118.	池田真由美, Hiromitsu Takizawa, 古川尊子, 西野豪志, Masakazu Goto, Koichiro Kajiura, Yasushi Nakagawa, Yukikiyo Kawakami, Mitsuteru Yoshida, Shoji Sakiyama, Kazuya Kondo and Akira Tangoku : 内科的治療抵抗性の乳児気管支肉芽に対してHo:YAGレーザー焼灼術を施行した1例, The Journal of the Japan Society for Respiratory Endoscopy, Vol.35, No.2, 222, 2013. (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1390001204754813696 (CiNii: 1390001204754813696)
119.	古川尊子, Mitsuteru Yoshida, Koichiro Kajiura, Shoji Sakiyama, Hiromitsu Takizawa, 森本雅美, Hirokazu Takechi, 池田真由美, 西野豪志, Yasushi Nakagawa, Yukikiyo Kawakami, Kazuya Kondo and Akira Tangoku : 当科における気管支鏡検査へのLung pointの経験, The Journal of the Japan Society for Respiratory Endoscopy, Vol.35, No.2, 227-228, 2013. (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1390282679731443840 (CiNii: 1390282679731443840)
120.	Koichiro Kajiura, Yukikiyo Kawakami, 池田真由美, 古川尊子, 森本雅美, 西野豪志, Masakazu Goto, Misako Nakagawa, Yota Yamamoto, Yoshihito Furukita, Hirokazu Takechi, Yasushi Nakagawa, Mitsuteru Yoshida, Hiromitsu Takizawa, Yukiko Tadokoro, Shoji Sakiyama, Kazuya Kondo and Akira Tangoku : YAGレーザー使用時の気管支鏡破損の1例, The Journal of the Japan Society for Respiratory Endoscopy, Vol.35, No.2, 228, 2013. (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1390282679731441664 (CiNii: 1390282679731441664)
121.	坂本晋一, Koichiro Kajiura, Hiromitsu Takizawa, Yasushi Nakagawa, 池田真由美, 古川尊子, 森本雅美, 西野豪志, Masakazu Goto, Misako Nakagawa, Yota Yamamoto, Yoshihito Furukita, Hirokazu Takechi, Mitsuteru Yoshida, Yukikiyo Kawakami, Yukiko Tadokoro, Shoji Sakiyama, Kazuya Kondo, Yoshimi Bando, 岡崎弘泰, Hisatsugu Goto, Yasuhiko Nishioka and Akira Tangoku : Erlotinibでinduction therapyを行ったIIIA期非小細胞肺癌の1手術例, Shikoku Acta Medica, Vol.68, No.5-6, 251-256, 2012. (Keyword) Carcinoembryonic Antigen(血液) (Tokushima University Institutional Repository) ● Metadata: 110365 (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1050282812441819136 (Tokushima University Institutional Repository: 110365, CiNii: 1050282812441819136)
122.	Hiromitsu Takizawa, Kazuya Kondo, Hiroaki Toba, Koichiro Kajiura, Ali Hamed Khalil Abdellah, Shoji Sakiyama and Akira Tangoku : Computed tomography lymphography by transbronchial injection of iopamidol to identify sentinel nodes in preoperative patients with non-small cell lung cancer : A pilot study, Journal of Thoracic and Cardiovascular Surgery, Vol.144, No.1, 94-99, 2012. (Summary) The objective of the present study was to assess the safety and feasibility of computed tomography lymphography by transbronchial injection of a water-soluble extracellular computed tomography contrast agent. From April 2010 to May 2011, patients with clinical stage I non-small cell lung cancer who were candidates for lobectomy were enrolled in the present study. An ultrathin bronchoscope was inserted to the target bronchus under the guidance of virtual bronchoscopic navigation images. Computed tomography images of the chest were obtained 0.5 and 5 minutes after 2 or 3 mL of iopamidol was injected through a microcatheter. Sentinel nodes were identified when the maximum computed tomography attenuation value of the lymph nodes on the postcontrast computed tomography images increased by 30 Hounsfield units or more compared with the precontrast images. Patients underwent lobectomy with standard lymph node dissection. The ultrathin bronchoscope could access the targeted bronchus, and iopamidol was delivered into the peritumoral area in all 13 patients without any complications. Sentinel nodes were identified in 12 (92.3%) of the 13 patients. The average number of sentinel nodes was 1.5 (range, 1-2). Pathologic examination revealed metastatic lymph nodes in 2 patients. Metastatic nodes were included with the sentinel nodes. Computed tomography lymphography by transbronchial injection of iopamidol was a safe and feasible method to identify the sentinel nodes in patients with clinical stage I non-small cell lung cancer. (Keyword) Aged / Carcinoma, Non-Small-Cell Lung / Contrast Media / Female / Humans / Injections / Iopamidol / Lung Neoplasms / Lymphography / Male / Middle Aged / Neoplasm Staging / Pilot Projects / Pneumonectomy / Sentinel Lymph Node Biopsy / Thoracic Surgery, Video-Assisted / Tomography, X-Ray Computed (Link to Publication Site) ● Publication site (DOI): 10.1016/j.jtcvs.2012.03.040 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 22507846 ● Search Scopus @ Elsevier (PMID): 22507846 ● Search Scopus @ Elsevier (DOI): 10.1016/j.jtcvs.2012.03.040 (DOI: 10.1016/j.jtcvs.2012.03.040, PubMed: 22507846)
123.	Hiroaki Toba, Shoji Sakiyama, 森本雅美, Koichiro Kajiura, Yasushi Nakagawa, Yukikiyo Kawakami, Hiromitsu Takizawa, Koichiro Kenzaki, Kazuya Kondo and Akira Tangoku : A Pediatric Case of Removal of a Bronchial Foreign Body Using a Laryngeal Mask Airway, The Journal of the Japan Society for Respiratory Endoscopy, Vol.34, No.2, 180-183, 2012. (Summary) Background. We report a pediatric case of remove of bronchial foreign body using a laryngeal mask airway and flexible bronchoscopy. Case. A 18-month-old girl accidentally inhaled a peanut. Afterwards she entered another hospital with a chief complaint of wheezing and received antibiotic treatment. On the next day, an abnormal shadow was pointed out, which was suspected to indicate a foreign body, in the left main bronchus. Chest computed tomography (CT) scan was carried to our hospital. On the same day, after the airway was cleared using a laryngeal mask airway (LMA size 2.0) under general anesthesia, a flexible bronchoscope (external diameter 4.0 mm) was inserted. The foreign body was successfully removed with a balloon-tip catheter. The foreign body was a peanut. Conclusion. By using a laryngeal mask airway, we could maintain available ventilation and enable a smooth procedure using a flexible bronchoscope while removing a pediatric bronchial foreign body. (Keyword) *異物(治療,X線診断) (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1390282679727797504 (CiNii: 1390282679727797504)
124.	Abdellah Hamed Khalil Ali, Hiromitsu Takizawa, Kazuya Kondo, Yasushi Nakagawa, Hiroaki Toba, Narmisheekh Khasag, Koichiro Kenzaki, Shoji Sakiyama, Hamdy Ali Mohammadien, Essam Ahmed Mokhtar and Akira Tangoku : Follow-up using fluorescence bronchoscopy for the patients with photodynamic therapy treated early lung cancer., The Journal of Medical Investigation : JMI, Vol.58, No.1-2, 46-55, 2011. (Summary) To evaluate the accuracy of fluorescence bronchoscopy by precise histological analysis of the photodynamic therapy (PDT) treated lesions. (Tokushima University Institutional Repository) ● Metadata: 75865 (Link to Publication Site) ● Publication site (DOI): 10.2152/jmi.58.46 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 21372486 ● Search Scopus @ Elsevier (PMID): 21372486 ● Search Scopus @ Elsevier (DOI): 10.2152/jmi.58.46 (Tokushima University Institutional Repository: 75865, DOI: 10.2152/jmi.58.46, PubMed: 21372486)
125.	Khalil Abdellah Hamed Ali, Hiromitsu Takizawa, Kazuya Kondo, Hisashi Matsuoka, Hiroaki Toba, Yasushi Nakagawa, Koichiro Kenzaki, Shoji Sakiyama, Soji Kakiuchi, Yoshitaka Sekido, Saburo Sone and Akira Tangoku : 5-Aminolevulinic acid-induced fluorescence diagnosis of pleural malignant tumor., Lung Cancer, 2011. (Summary) BACKGROUND: It is known that endogenously synthesized protoporphyrin IX (PpIX) following the administration of 5-aminolevulinic acid (5-ALA) is an effective photosensitizer for photodynamic diagnosis (PDD). We tested in vivo and in vitro susceptibility of human lung cancer and mesothelioma cells to photodynamic diagnosis (PDD) using 5-aminolevulinic acid (5-ALA) as a photosensitizer. METHODS: Human lung cancer cell lines A549, Ma44-3, FT821 and human mesothelioma cell lines MSTO-211H, NCI-H290, Y-MESO-14 were incubated with 0.03% 5-ALA for 4h. After incubation, protoporphyrin IX (PpIX) fluorescence was detected using a fluorescence microscope. Pleural carcinosis was induced in severe combined immunodeficiency disease mice using the previous cell lines to test the efficacy of PDD in vivo. The mice were sacrificed 4h after oral administration of 400mg/kg of 5-ALA. We counted the visible tumors under white light then fluorescence light. RESULTS: In vitro, clear red fluorescence was observed in all cell lines. The mean fluorescence intensity was stronger in A549 and FT821 cells than Ma44-3 cells (165.59±26.49, 157.62±18.93 vs. 104.01±17.58). Also, MSTO-211H and NCI-H290 cells had stronger fluorescence intensity than Y-MESO-14 cells (142.51±26.85, 165.16±12.91 vs. 92.31±8.69). In vivo, the tumor detection rate of fluorescence diagnosis was 1.1-4.5 times higher than that of white light. The mean number of metastases detected by the PDD was significantly higher than that of white light for FT821 (p=0.004), Ma44-3 (p=0.006) and Y-MESO-14 cell lines (p=0.005), but not for A549, NCI-H290 and MSTO-211H cell lines. Small lesions were detected by fluorescence diagnosis even though the lesions were invisible macroscopically under white light. CONCLUSION: Our results suggest the possibility of clinical application of fluorescence diagnosis with intrapleural malignant tumors. (Link to Publication Site) ● Publication site (DOI): 10.1016/j.lungcan.2011.01.031 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 21353719 ● Search Scopus @ Elsevier (PMID): 21353719 ● Search Scopus @ Elsevier (DOI): 10.1016/j.lungcan.2011.01.031 (DOI: 10.1016/j.lungcan.2011.01.031, PubMed: 21353719)
126.	Abdellah H. K. Ali, Kazuya Kondo, Toshiaki Namura, Yoshitaka Senba, Hiromitsu Takizawa, Yasushi Nakagawa, Hiroaki Toba, Koichiro Kenzaki, Shoji Sakiyama and Akira Tangoku : Aberrant DNA methylation of some tumor suppressor genes in lung cancers from workers with chromate exposure., Molecular Carcinogenesis, Vol.50, No.2, 89-99, 2010. (Summary) Our previous studies revealed a variety of genetic changes in lung cancers from chromate-exposed workers (chromate lung cancer). In the present study, we examined epigenetic changes in chromate lung cancers. Nested-methylation-specific PCR was employed in studying the methylation of CpG islands in the APC, MGMT, hMLH1 genes in 36 chromate lung cancers and 25 nonchromate lung cancers. Methylation in chromate lung cancers was detected at 86% for APC, 20% for MGMT, and 28% for hMLH1. Whereas, it occurred at lower frequencies in nonchromate lung cancers, particularly in APC (44%) and hMLH1 (0%) genes. Our previous study showed that methylation of p16 gene in chromate lung cancer and nonchromate lung cancer was 33% and 26%, respectively. The mean methylation index (MI), a reflection of the overall methylation status, was significantly higher in chromate lung cancers than nonchromate lung cancers (0.41 vs. 0.21, P=0.001). Methylation of multiple genes (particularly hMLH1, p16, and APC genes) had experienced more than 15 yr of chromate exposure in chromate lung cancer (MI: <15 yr; 0.19, ≥ 15 yr, 0.42). There is a significant correlation of p16 and hMLH1 methylation with the expressional decrease or loss of the corresponding gene products (P=0.037 and 0.024) respectively, and an inverse correlation between APC and MGMT methylation (P = 0.014). This study provides a novel evidence for the chromium carcinogenesis that chromate lung cancer is linked to the progressive methylation of some tumor suppressor genes, which may be related to genomic instability. (Keyword) Adaptor Proteins, Signal Transducing / Adult / Aged / Chromates / CpG Islands / DNA Methylation / DNA Modification Methylases / DNA Repair Enzymes / Epigenesis, Genetic / Genes, APC / Genes, Tumor Suppressor / Humans / Lung Neoplasms / Middle Aged / Nuclear Proteins / Occupational Diseases / Occupational Exposure / Promoter Regions, Genetic / Tumor Suppressor Proteins (Link to Publication Site) ● Publication site (DOI): 10.1002/mc.20697 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 21229606 ● Search Scopus @ Elsevier (PMID): 21229606 ● Search Scopus @ Elsevier (DOI): 10.1002/mc.20697 (DOI: 10.1002/mc.20697, PubMed: 21229606)
127.	Naoya Kawakita, Hiroaki Toba, Shoji Sakiyama, Toru Sawada, Yota Yamamoto, Yasushi Nakagawa, Hiromitsu Takizawa, Koichiro Kenzaki, Kazuya Kondo and Akira Tangoku : [Lung cancer in patient with a common trunk of left pulmonary veins; report of two cases]., The Japanese Journal of Thoracic Surgery, Vol.63, No.10, 915-918, 2010. (Summary) A 69-year-old man and a 53-year-old man with lung cancer of left upper lobe underwent pulmonary resection. A preoperative chest computed tomography (CT) scan showed the left superior and inferior pulmonary veins forming a common trunk. In the former case, the common trunk was misidentified as the superior pulmonary vein. The latter was recognized preoperatively by using 3-dimensional CT, and successfully performed left superior segmentectomy. This variation type is surgically important because of a potential risk of intraoperative bleeding and damage to pulmonary circulation during pulmonary resection. (Keyword) Aged / Cardiovascular Abnormalities / Humans / Lung Neoplasms / Male / Middle Aged / Pneumonectomy / Pulmonary Veins / Tomography, X-Ray Computed (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 20845705 ● Search Scopus @ Elsevier (PMID): 20845705 (PubMed: 20845705)
128.	Hiroaki Toba, Kazuya Kondo, Hideki Otsuka, Hiromitsu Takizawa, Koichiro Kenzaki, Shoji Sakiyama and Akira Tangoku : Diagnosis of the presence of lymph node metastasis and decision of operative indication using fluorodeoxyglucose-positron emission tomography and computed tomography in patients with primary lung cancer., The Journal of Medical Investigation : JMI, Vol.57, No.3-4, 305-313, 2010. (Summary) PET/CT is superior to CT scan in lymph node staging. However, because the false-positive rate is high in PET-positive lymph nodes measuring less than 1 cm in diameter, we think that clinical background should be considered and other modalities or histological examinations should be undertaken if necessary. J. Med. Invest. 57: 305-313, August, 2010. (Keyword) Aged / Diagnostic Errors / Female / Fluorodeoxyglucose F18 / Humans / Lung Neoplasms / Lymph Node Excision / Lymphatic Metastasis / Male / Middle Aged / Neoplasm Staging / Positron-Emission Tomography / Radiopharmaceuticals / Retrospective Studies / Tomography, X-Ray Computed (Tokushima University Institutional Repository) ● Metadata: 73983 (Link to Publication Site) ● Publication site (DOI): 10.2152/jmi.57.305 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 20847531 ● Search Scopus @ Elsevier (PMID): 20847531 ● Search Scopus @ Elsevier (DOI): 10.2152/jmi.57.305 (Tokushima University Institutional Repository: 73983, DOI: 10.2152/jmi.57.305, PubMed: 20847531)
129.	Koichiro Kenzaki, Shoji Sakiyama, Hideki Tomimoto, Hiroaki Toba, Yasushi Nakagawa, Hiromitsu Takizawa, Kazuya Kondo, Saburo Sone and Akira Tangoku : [Clinical analysis of elderly patients with primary lung cancer]., The Japanese Journal of Thoracic Surgery, Vol.63, No.7, 519-526, 2010. (Summary) We clinically reviewed 33 surgery patients and 15 non-surgery patients aged 80 years or older with primary lung cancer treated at our hospital. The surgery group consisted of 21 males and 12 females (82.0 +/- 1.9 years old). The surgical procedures were 1 pneumonectomy, 19 lobectomies (1 bronchoplasty), 4 segmentectomies and 9 partial resections. The cancer types were 17 adenocarcinomas, 14 squamous cell carcinomas and 2 others. The stagings were 24 in stage I, 4 in stage II and 5 in stage III. There were no direct surgical deaths within 30 days post operatively. There have been 9 other disease-related deaths to date (27%). The non-surgery group consisted of 9 males and 6 females (81.7 +/- 1.5 years old). Treatment procedures consisted of radiationtherapy in 11, chemotherapy in 2 and best supportive care in 3. The cancer types were 2 adenocarcinomas, 11 squamous cell carcinomas and 2 others. The stagings were 7 in stage I, 4 in stage II and 4 in stage III. There have been 3 other disease-related deaths to date (20%). We must carefully select the therapeutic approach for elderly lung cancer patients, because the other disease-related death rates of both groups were high. The 5-year survival rate of stage I patients in the surgical group was relatively good (60.2%). There were long-term survival (7 5-year survivors) in the surgical group. Since there were some cases of radiation pneumonia in the group receiving radiation therapy, it would be better to perform surgery for elderly patients with lung cancer, especially those with stage I disease. For elderly patients, it is important to consider quality of life as well as the survival rate. (Keyword) Age Factors / Aged / Aged, 80 and over / Female / Humans / Lung Neoplasms / Male / Pneumonectomy (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 20662228 ● Summary page in Scopus @ Elsevier: 2-s2.0-77956070239 (PubMed: 20662228, Elsevier: Scopus)
130.	Naoko Matsui, Shunya Nakane, Fumi Saitou, Izumi Ohigashi, Yasushi Nakagawa, Hirotsugu Kurobe, Hiromitsu Takizawa, Takao Mitsui, Kazuya Kondo, Tetsuya Kitagawa, Yousuke Takahama and Ryuji Kaji : Undiminished regulatory T cells in the thymus of myathenia gravis patients, Neurology, Vol.74, No.10, 816-820, 2010. (Summary) The thymus has been implicated as a possible site of origin that triggers autoimmunity in myasthenia gravis (MG). Although several groups have suggested that the decrease in the number of regulatory T (Treg) cells contributes to the onset of MG, the exact role of Treg cells in MG remains unclear. To address this point, we examined the number and distribution of Treg cells in a large number of patients with MG. Immunohistofluorescence analysis of Foxp3 along with CD4 and CD8 was performed in thymic sections of MG (+) (n = 24) and MG (-) patients (n = 27). Circulating CD4(+)CD25(+) cells in the peripheral blood of patients with MG (n = 15) and age-matched healthy subjects (n = 15) were also analyzed. Foxp3(+)CD4(+)CD8(-) cells were predominantly found in the thymic medulla and their number declined with age. There was no significant difference in the number or the distribution of Foxp3(+)CD4(+)CD8(-) cells in the thymus between MG (+) and MG (-) patients. The number of circulating CD4(+)CD25(+) cells in the peripheral blood of patients with MG was not significantly altered compared to that in healthy subjects. The cellularity of Treg cells in the thymus and circulation is not diminished in patients with myasthenia gravis. (Keyword) Age Factors / Antigens, CD / Cell Count / Female / Flow Cytometry / Forkhead Transcription Factors / Humans / Male / Myasthenia Gravis / T-Lymphocytes, Regulatory / Thymus Gland (Link to Publication Site) ● Publication site (DOI): 10.1212/WNL.0b013e3181d31e47 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 20211905 ● Search Scopus @ Elsevier (PMID): 20211905 ● Search Scopus @ Elsevier (DOI): 10.1212/WNL.0b013e3181d31e47 (DOI: 10.1212/WNL.0b013e3181d31e47, PubMed: 20211905)
131.	河北直也, Hiromitsu Takizawa, Hiroaki Toba, Koichiro Kenzaki, Shoji Sakiyama and Kazuya Kondo : Gefitinib耐性後に切除した肺腺癌術後肺転移の1例, The Journal of the Japanese Association for Chest Surgery, Vol.24, No.2, 42-45, 2010. (Link to Publication Site) ● Publication site (DOI): 10.2995/jacsurg.24.166 (Link to Search Site for Scientific Articles) ● Search Scopus @ Elsevier (DOI): 10.2995/jacsurg.24.166 (DOI: 10.2995/jacsurg.24.166)
132.	Hiromitsu Takizawa, Kazuya Kondo, Hiroaki Toba, Koichiro Kenzaki, Shoji Sakiyama and Akira Tangoku : Fluorescence diagnosis of lymph node metastasis of lung cancer in a mouse model., Oncology Reports, Vol.22, No.1, 17-21, 2009. (Summary) Fluorescence diagnosis of lymph node metastasis of non-small cell lung cancer has not been reported previously. This study was conducted to evaluate the feasibility of fluorescence detection using 5-aminolevulinic acid and mono-L-aspartyl chlorine e6 for lymph node metastasis in a lung cancer mouse model. Human lung cancer cell line Ma44-3, which forms metastatic lymph nodes in the mediastinum, was injected into the left lungs of 6 severe combined immunodeficiency disease mice. Two weeks after implantation, 2 groups of 3 mice received oral administration of 5-aminolevulinic acid (100 mg/kg) or intraperitoneal administration of mono-L-aspartyl chlorine e6 (5 mg/kg). Both lungs and mediastinal organs were removed en-bloc and illuminated with blue light (405 nm) to evaluate the detectability of lung tumors and metastatic lymph nodes in the mediastinum. These organs were evaluated histopathologically. Clear red fluorescence was observed in the lung tumors of all mice. Metastatic lymph nodes had formed in 5 of 6 mice and were detected by fluorescent detection in all 5 mice even though one of the lymph nodes was invisible macroscopically under white light. In conclusion, fluorescence diagnosis of lymph node metastasis is possible in a mouse model. The successful result with small lymph node metastasis suggests the possibility of clinical application. (Link to Publication Site) ● Publication site (DOI): 10.3892/or_00000400 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 19513499 ● Search Scopus @ Elsevier (PMID): 19513499 ● Search Scopus @ Elsevier (DOI): 10.3892/or_00000400 (DOI: 10.3892/or_00000400, PubMed: 19513499)
133.	Hiromichi Yamai, Takahiro Yoshida, Hiroaki Toba, Misako Kira, Hiromitsu Takizawa and Akira Tangoku : A case of anaplastic carcinoma of thyroid administered peroral fluorinated pyrimidine for long-term survival during three years, Japanese Journal of Cancer and Chemotherapy, Vol.36, No.6, 1021-1024, 2009. (Summary) We report a case of anaplastic carcinoma of the thyroid administered peroral fluorinated pyrimidine, providing longterm survival during three years. Three years ago, a 70-year-old woman diagnosed with anaplastic carcinoma of the thyroid was admitted for chemoradiation therapy after tumor resection and tracheostomy. The tumor was confirmed to remain on the margin of resected specimens by postoperative histopathology. Combination chemotherapy, including docetaxel, 5-fluorouracil, cisplatin, and radiotherapy, was performed for four weeks. After completion of radiotherapy, CT scan showed residual tumor and lytic clavicular bone findings. But the patient did not desire the same heavy chemotherapy, wishing rather to undergo chemotherapy as an outpatient, if possible. She received chemotherapy with S-1 which was peroral fluorinated pyrimidine for 9 months. In this period, PET-CT showed that accumulation of FDG and lytic clavicular bone findings were continuously confirmed. She was changed to tegafur-uracil(UFT)from S-1, because of myelosuppression. She is alive at this writing in good physical condition. CT shows no tumor growth and no remote metastasis. (Keyword) Administration, Oral / Aged / Antimetabolites, Antineoplastic / Antineoplastic Combined Chemotherapy Protocols / Carcinoma / Drug Combinations / Female / Humans / Oxonic Acid / Tegafur / Thyroid Neoplasms / Uracil (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 19542729 ● Search Scopus @ Elsevier (PMID): 19542729 (PubMed: 19542729)
134.	Hiromichi Yamai, Naruhiko Sawada, Takahiro Yoshida, Junnichi Seike, Hiromitsu Takizawa, Koichiro Kenzaki, Takanori Miyoshi, Kazuya Kondo, Yoshimi Bando, Yoshinari Ohnishi and Akira Tangoku : Triterpenes augment the inhibitory effects of anticancer drugs on growth of human esophageal carcinoma cells in vitro and suppress experimental metastasis in vivo., International Journal of Cancer, Vol.125, No.4, 952-960, 2009. (Summary) The antineoplastic effects of combinations of anticancer drugs (5-fluorouracil, irinotecan and cisplatin) and triterpenes (ursolic acid, betulinic acid, oleanolic acid and a Japanese apricot extract (JAE) containing triterpenes) on esophageal squamous carcinoma cells were examined by the WST-8 (2-(2-methoxy- 4-nitrophenyl)-3-(4-nitrophenyl)-5-(2,4-disulfophenyl)-2H-tetrazolium, monosodium salt) assay in vitro and by an animal model in vivo. Triterpenes and JAE showed additive and synergistic cytotoxic effects, respectively, on esophageal squamous carcinoma cells (YES-2cells) by combinational use of 5-fluorouracil. JAE and 5-fluorouracil induced cell cycle arrest at G2/M phase and at S phase, respectively, and caused apoptosis in YES-2 cells. A new animal model of esophageal cancer causing tumor colonization of the peritoneal cavity and producing bloody ascites was made by injecting YES-2 cells into the peritoneal cavity of a severe combined immunodeficiency mouse. In this model, 5-fluorouracil inhibited colonization of tumor cells in the peritoneum. The addition of JAE to 5-fluorouracil augmented the suppression of experimental metastasis of the peritoneum. The numbers of peritoneal nodules of more than 2 mm in diameter in mice treated with 5-fluorouracil and JAE were less than those in mice treated with 5-fluorouracil alone or JAE alone. These results suggest that triterpenes, especially JAE, are effective supplements for enhancing the chemotherapeutic effect of 5-fluorouracil on esophageal cancer. (c) 2009 UICC. (Link to Publication Site) ● Publication site (DOI): 10.1002/ijc.24433 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 19462449 ● Search Scopus @ Elsevier (PMID): 19462449 ● Search Scopus @ Elsevier (DOI): 10.1002/ijc.24433 (DOI: 10.1002/ijc.24433, PubMed: 19462449)
135.	Hiroaki Toba, Kazuya Kondo, Hiromitsu Takizawa and Akira Tangoku : Recurrent thymoma with a pleural dissemination invading the intervertebral foramen., European Journal of Cardio-Thoracic Surgery, Vol.35, No.5, 917-919, 2009. (Summary) We report a rare case of recurrent thymoma with pleural dissemination invading the intervertebral foramen. A woman with Masaoka's stage IVa thymoma with myasthenia gravis (MG) underwent macroscopically complete resection. After 45 months, she developed back pain. Computed tomography (CT) of the chest demonstrated a mass in the right thoracic cavity invading the intervertebral foramen between thoracic vertebrae 10 and 11. She underwent complete resection of the tumor and postoperative radiotherapy. The resected specimen was histologically diagnosed as a pleural dissemination from thymoma. There has been no local recurrence. (Link to Publication Site) ● Publication site (DOI): 10.1016/j.ejcts.2009.01.036 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 19269845 ● Search Scopus @ Elsevier (PMID): 19269845 ● Search Scopus @ Elsevier (DOI): 10.1016/j.ejcts.2009.01.036 (DOI: 10.1016/j.ejcts.2009.01.036, PubMed: 19269845)
136.	Hiroaki Toba, Shoji Sakiyama, M Morimoto, Hiromitsu Takizawa, Koichiro Kenzaki, Kazuya Kondo, Yoshimi Bando and Akira Tangoku : Surgically treated pleomorphic carcinoma of the lung, The Japanese Journal of Thoracic Surgery, Vol.62, No.3, 202-206, 2009. (Summary) We experienced 3 resected cases of pleomorphic carcinoma of the lung. Each cases were 74-year-old man (case 1), 74-year-old woman (case 2) and 69-year-old man (case 3). Two patients (case 1 and 2) were histologically diagnosed as pleomorphic carcinoma composed of spindle cell carcinoma with giant cell carcinoma. One patient (case 3) was similarly diagnosed as pleomorphic carcinoma composed of spindle cell carcinoma with adenocarcinoma and squamous cell carcinoma. Although lymph nodes metastasis were not recognized in all patients, invasion to vessels were recognized in 2 patients (case 1 and 3). In one patient (case 1), recurrence was recognized at contralateral side 1 month after surgery and he died of other disease 2 months after surgery. The other 2 patients were alive without recurrence 24 and 5 months after surgery. Recently it is reported that recurrence is recognized at early phase after surgery and prognosis is poor in a case with vessel invasions in spite of pathological NO state. Since one patient (case 3) had nonmetastatic lymph nodes with vessel invasions, careful observation is considered to be necessary. (Keyword) Aged / Aged, 80 and over / Carcinoma / Diagnostic Imaging / Fatal Outcome / Female / Humans / Lung Neoplasms / Male / Neoplasm Staging / Treatment Outcome (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 19280950 ● Search Scopus @ Elsevier (PMID): 19280950 (PubMed: 19280950)
137.	Koichiro Kenzaki, Shoji Sakiyama, Hiroaki Toba, Yasushi Nakagawa, Hiromitsu Takizawa, Kazuya Kondo and Akira Tangoku : Clinical analysis of tracheoplasty and bronchoplasty in primary lung cancer, The Japanese Journal of Thoracic Surgery, Vol.61, No.11, 951-956, 2008. (Summary) In our department, there were 482 thoracic surgeries for primary lung cancer between 1994 and 2007. We clinically reviewed cases that underwent tracheoplasty or bronchoplasty (n = 22, 4.6%). The patients consisted of 21 males and 1 female (66.5 +/- 12.0 years-old). All patients were smokers. The tissue forms were 19 squamous cell carcinomas, 2 adenocarcinomas, 1 large cell carcinoma, 1 adenoid cystic carcinoma and 1 carcinoid, including 2 multiple carcinomas. Sleeve resections involved the trachea in 1, upper lobes in 13, lower lobes in 3, upper-middle lobes in 2 and intermediate bronchus in 1. Wedge resections were performed in the upper lobes in 2. Fourteen reconstructions were performed. We ordinarily sutured the trachea and bronchus in any case, using a single outside knot. There was no leakage at the anastomosis. There were 2 hospital deaths. There were 4 cancer deaths, including 2 local recurrences. There were 4 patients demonstrating stenosis post operatively. There were 3 stenoses among 4 preoperative radiation therapies. We considered that radiation therapy disturbed the repair of the anastomosis. There were 8 pneumonia patients who developed post operatively. There were 2 operative hospital deaths among 3 angio-bronchoplasties without coverage. Recently, we have routinely covered the anastomosis at the reconstruction site and have not experienced any major complications. (Keyword) Aged / Bronchi / Female / Humans / Lung Neoplasms / Male / Middle Aged / Pneumonectomy / Prognosis / Radiotherapy, Adjuvant / Reconstructive Surgical Procedures / Thoracic Surgical Procedures / Trachea (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 18939431 ● Search Scopus @ Elsevier (PMID): 18939431 (PubMed: 18939431)
138.	Yukiko Hirose, Kazuya Kondo, Hiromitsu Takizawa, Taeko Nagao, Yasushi Nakagawa, Haruhiko Fujino, Hiroaki Toba, Koichiro Kenzaki, Shoji Sakiyama and Akira Tangoku : Aberrant methylation of tumour-related genes in thymic epithelial tumours., Lung Cancer, Vol.64, No.2, 155-159, 2008. (Summary) BACKGROUND: Thymoma is an uncommon neoplasm derived from epithelial cells of the thymus. Few studies have addressed the genetic alterations that occur in the tumourigenesis of thymoma. METHODS: We examined aberrant DNA methylation of DAP-K, p-16, MGMT and HPP1 genes in 26 thymomas and 6 thymic carcinoma to clarify the association between aberrant DNA methylation and clinicopathological features. RESULTS: Fifteen (47%) of 32 thymic epithelial tumours showed aberrant methylation. Aberrant methylation was more frequent in thymic carcinoma (86%) than in thymoma (29%). Moreover, the frequency of tumours with methylation of multiple genes in thymic carcinoma was higher than in thymoma (60% vs 20%). In thymoma, the frequency of tumour methylation, including the type A tumour component (28%), was lower than that of tumours with type B tumour component (42%). MGMT methylation was detected in 23% of thymoma and in 83% of thymic carcinoma. The frequency of methylation of the MGMT gene in both tumours was high compared with the other 3 genes. CONCLUSIONS: Aberrant DNA methylation was more frequent in thymic carcinoma than in thymoma, and the frequency of DNA methylation in thymic epithelial tumours is roughly parallel to their malignant behaviour. (Link to Publication Site) ● Publication site (DOI): 10.1016/j.lungcan.2008.07.015 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 18778870 ● Search Scopus @ Elsevier (PMID): 18778870 ● Search Scopus @ Elsevier (DOI): 10.1016/j.lungcan.2008.07.015 (DOI: 10.1016/j.lungcan.2008.07.015, PubMed: 18778870)
139.	Hiromitsu Takizawa, Kazuya Kondo, Hisashi Matsuoka, Koh Uyama, Hiroaki Toba, Koichiro Kenzaki, Shoji Sakiyama, Akira Tangoku, Kazumasa Miura, Kiyoshi Yoshizawa and Junji Morita : Effect of mediastinal lymph nodes sampling in patients with clinical stage I non-small cell lung cancer, The Journal of Medical Investigation : JMI, Vol.55, No.1,2, 37-43, 2008. (Summary) Systematic nodal dissection has been recommended for patients with resectable non-small cell lung cancer because of its staging accuracy. However, in patients with clinical stage I non-small cell lung cancer whether systematic nodal dissection provides more benefits than mediastinal lymph node sampling or not is controversial. In this retrospective study, we evaluated the effect of mediastinal lymph node sampling in patients with clinical stage I NSCLC. One hundred and nineteen consecutive patients with clinical stage I NSCLC, who underwent curative operation between January 1994 and December 2000, were retrospectively reviewed (dissection group = 58: sampling group= 61). Systematic nodal dissection was defined as complete removal of mediastinal lymph node, and mediastinal lymph node sampling was defined as removal of lymph node levels 3, 4, and 7 for right-sided tumors and levels 5, 6, and 7 for left-sided tumors. The total number of removed mediastinal lymph nodes in patients who underwent systematic nodal dissection was 22.1 +/- 9.7, which was significantly higher than that in patients who underwent mediastinal lymph node sampling of 11.4 +/- 7.0 (p < 0.001). Postoperatively N2 disease was detected in 8 patients (13.8%) in the dissection group and 7 (11.5%) in the sampling group. After the median follow up of 79 months, the cancer specific survival rate at 5 year was 78.0% in the dissection group and 76.2% in the sampling group (p = 0.60). Mediastinal lymph node sampling showed the similar effect to systematic nodal dissection in patients with clinical stage I non-small cell lung cancer. (Keyword) Adult / Aged / Aged, 80 and over / Carcinoma, Small Cell / Female / Follow-Up Studies / Humans / Lung Neoplasms / Lymph Node Excision / Lymph Nodes / Lymphatic Metastasis / Male / Mediastinum / Middle Aged / Neoplasm Staging / Pneumonectomy / Prognosis / Retrospective Studies / Survival Rate (Tokushima University Institutional Repository) ● Metadata: 110836 (Link to Publication Site) ● Publication site (DOI): 10.2152/jmi.55.37 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 18319543 ● Search Scopus @ Elsevier (PMID): 18319543 ● Search Scopus @ Elsevier (DOI): 10.2152/jmi.55.37 (Tokushima University Institutional Repository: 110836, DOI: 10.2152/jmi.55.37, PubMed: 18319543)
140.	Kazuya Kondo, Takanori Miyoshi, Haruhiko Fujino, Hiromitsu Takizawa, Satoshi Imai, Naoki Kobayashi, Koichiro Kenzaki, Shoji Sakiyama and Akira Tangoku : Photodynamic therapy using a second generation photosensitizer, Talaporfin, Photodiagnosis and Photodynamic Therapy, Vol.4, No.4, 269-274, 2007. (Summary) Background: Photodynamic therapy (PDT) using Talaporfin is an attractive treatment for centraltype early lung cancer. It was noted that some patients had altered levels of arterial oxygen saturation as indicated by pulse oximeter (SpO2) and arterial oxygen saturation levels in blood gas analysis (SaO2) during PDT. The present experiments were designed to provide an explanation for these findings. Methods: The influence of Talaporfin on SpO2 using in vitro and in vivo experiments, and clinically, was examined. Results: Our in vitro and in vivo experiments showed a linear relationship between Talaporfin concentration in the plasma and the SpO2 level (R = 0.9957 and 0.9837). The apparent SpO2 level decreased according to the increase of Talaporfin concentration in the plasma. In two patients with PDT, SpO2 levels at 4 6 h and 24 h after Talaporfin administration were 93% and 97%, respectively. Conclusions: Talaporfin raised blood absorbance at 660nm with a pulse oximeter. It appeared that the presence of the drug falsely decreased the level of SpO2 since SpO2 did not actually change. (Link to Publication Site) ● Publication site (DOI): 10.1016/j.pdpdt.2007.06.001 (Link to Search Site for Scientific Articles) ● Search Scopus @ Elsevier (DOI): 10.1016/j.pdpdt.2007.06.001 (DOI: 10.1016/j.pdpdt.2007.06.001)
141.	Hiromitsu Takizawa, Kazuya Kondo, H Fujino, Koichiro Kenzaki, T Miyoshi, Shoji Sakiyama and A Tangoku : The balance of VEGF-C and VEGFR-3 mRNA is a predictor of lymph node metastasis in non-small cell lung cancer., British Journal of Cancer, Vol.95, No.1, 75-79, 2006. (Summary) A positive association between vascular endothelial growth factor-C (VEGF-C) expression and lymph node metastasis has been reported in several cancers. However, the relationship of VEGF-C and lymph node metastasis in some cancers, including non-small cell lung cancer (NSCLC), is controversial. We evaluated the VEGF-C and vascular endothelial growth factor receptor-3 (VEGFR-3) expression in NSCLC samples from patients who had undergone surgery between 1998 and 2002 using real-time quantitative RT-PCR and immunohistochemical staining. We failed to find a positive association between VEGF-C and VEGFR-3 mRNA expression and lymph node metastasis in NSCLC. An immunohistological study demonstrated that VEGF-C was expressed not only in cancer cells, but also in macrophages in NSCLC, and that VEGFR-3 was expressed in cancer cells, macrophages, type II pneumocytes and lymph vessels. The VEGF-C/VEGFR-3 ratio of the node-positive group was significantly higher than that of the node-negative group. Immunohistochemical staining showed that VEGFR-3 was mainly expressed in cancer cells. The immunoreactivity of VEGF-C and VEGFR-3 was roughly correlated to the mRNA levels of VEGF-C and VEGFR-3 in real-time PCR. VEGF-C mRNA alone has no positive association with lymph node metastasis in NSCLC. The VEGF-C/VEGFR-3 ratio was positively associated with lymph node metastasis in NSCLC. This suggests that VEGF-C promotes lymph node metastasis while being influenced by the strength of the VEGF-C autocrine loop, and the VEGF-C/VEGFR-3 ratio can be a useful predictor of lymph node metastasis in NSCLC. (Keyword) Adult / Aged / Aged, 80 and over / Carcinoma, Non-Small-Cell Lung / Female / Gene Expression Profiling / Humans / Immunohistochemistry / Lung Neoplasms / Lymph Nodes / Lymphatic Metastasis / Male / Middle Aged / RNA, Messenger / Reverse Transcriptase Polymerase Chain Reaction / Vascular Endothelial Growth Factor C / Vascular Endothelial Growth Factor Receptor-3 (Link to Publication Site) ● Publication site (DOI): 10.1038/sj.bjc.6603209 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 16755294 ● Search Scopus @ Elsevier (PMID): 16755294 ● Search Scopus @ Elsevier (DOI): 10.1038/sj.bjc.6603209 (DOI: 10.1038/sj.bjc.6603209, PubMed: 16755294)
142.	Koichiro Kenzaki, Shoji Sakiyama, Kazuya Kondo, Mitsuteru Yoshida, Taeko Nagao, Y Nakagawa, Hiromitsu Takizawa, Takanori Miyoshi and Akira Tangoku : Clinical analysis of operative and hospital deaths in primary lung cancer, The Japanese Journal of Thoracic Surgery, Vol.59, No.5, 347-52, 2006. (Summary) In our department, there were 313 thoracic surgeries for primary lung cancer from January 1994 to December 2003. We clinically reviewed for the operative and hospital death (n=18, 5.8%). The patients were 16 males and 2 females (70.6 +/- 5.6 years old). The surgical procedures were 4 pneumonectomies, 13 lobectomies (3 bronchoplasties) and 1 partial resection. The mean interval until postoperative death was 122.5 +/- 156.1 days. There were 5 direct operative deaths within 30 days (1.6%). There were 4 cancer deaths, 2 hemoptyses, 2 operative bleeding, 2 thromboses, 2 cerebral hemorrhages, 1 pyothorax, 1 pneumonia, 1 respiratory failure, 1 multiple organ failure after chemotherapy and 2 unexplained deaths. The patients with pneumonectomy or aged significantly had high mortality. For postoperative complications such as hemoptysis or bleeding, perioperative management that takes these issues into consideration is needed. Furthermore, we must carefully review the preoperative evaluation and combined treatment, because there were many cancer deaths among cases showing early recurrence and metastasis. (Keyword) Adenocarcinoma / Aged / Aged, 80 and over / Carcinoma, Squamous Cell / Female / Hospital Mortality / Humans / Lung Neoplasms / Male / Middle Aged / Pneumonectomy (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 16715882 ● Search Scopus @ Elsevier (PMID): 16715882 (PubMed: 16715882)
143.	Koichiro Kenzaki, Shoji Sakiyama, Kazuya Kondo, Mitsuteru Yoshida, Yukikiyo Kawakami, Masatsugu Takehisa, Hiromitsu Takizawa, Takanori Miyoshi, Yoshimi Bando, Akira Tangoku and Mingyao Liu : Lung regeneration: implantation of fetal rat lung fragments into adult rat lung parenchyma., Journal of Thoracic and Cardiovascular Surgery, Vol.131, No.5, 1148-1153, 2006. (Summary) OBJECTIVE: The capability of regeneration of lung tissues in adults is limited after chronic destruction. Bone marrow-derived stem cells, retinoic acid, growth factors, and other approaches have been attempted to promote or facilitate this process. We hypothesized that fetal lung tissues, with great potential for growth and differentiation, could be used for lung regeneration. METHODS: Day 17 fetal lung tissue fragments at the pseudoglandular stage of lung development from Lewis rats were implanted into adult Lewis rat lungs. For group 1, fetal lung fragments were injected into the adult left lung parenchyma; for group 2, fetal fragments were injected with the left lung partially resected; for group 3, adult fragments were injected; and for groups 4 and 5, fetal fragments were implanted into the omentum and subcutaneous tissue, respectively. RESULTS: The grafts implanted into pulmonary parenchyma were differentiated with opening of the alveolar space after 4 weeks and were advanced further with morphologic features similar to those of neonatal lungs after 8 and 12 weeks. The implants were connected with pulmonary circulation determined by means of perfusion with India ink. These changes appeared to be further enhanced in animals with partial lung resection that might have facilitated the maturation of implanted fetal lung tissues through mechanical factors, soluble factors, or both. Fetal lung tissues did not mature when implanted into the omentum or subcutaneous tissue. Adult lung fragments did not expand after being reimplanted back into the same animal. CONCLUSIONS: Fetal lung tissue might be an option for further investigation into lung regeneration. (Keyword) Age Factors / Animals / Female / Fetus / Lung / Lung Transplantation / Models, Animal / Pneumonectomy / Pregnancy / Rats / Rats, Inbred Lew / Regeneration (Link to Publication Site) ● Publication site (DOI): 10.1016/j.jtcvs.2005.11.041 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 16678603 ● Search Scopus @ Elsevier (PMID): 16678603 ● Search Scopus @ Elsevier (DOI): 10.1016/j.jtcvs.2005.11.041 (DOI: 10.1016/j.jtcvs.2005.11.041, PubMed: 16678603)
144.	Takanori Miyoshi, Kazuya Kondo, Hiromitsu Takizawa, Koichiro Kenzaki, Haruhiko Fujino, Shoji Sakiyama and Akira Tangoku : Fluoroscopy-assisted thoracoscopic resection of pulmonary nodules after computed tomography--guided bronchoscopic metallic coil marking., Journal of Thoracic and Cardiovascular Surgery, Vol.131, No.3, 704-710, 2006. (Summary) OBJECTIVE: To localize small and deeply situated pulmonary nodules during thoracoscopy with roentgenographic fluoroscopy, we developed a marking procedure that uses a metallic coil. METHODS: Nine patients underwent video-assisted thoracoscopic surgery for the removal of 11 pulmonary lesions. Fluoroscopy-assisted thoracoscopic surgery after computed tomography-guided bronchoscopic metallic coil marking was performed with an ultrathin bronchoscope, with simulation by means of virtual bronchoscopy. During thoracoscopy, a C-arm-shaped roentgenographic fluoroscope was used to detect the radiopaque nodules. RESULTS: The marking procedure took 15 to 60 minutes from insertion to removal of the bronchoscope. There were no complications from the marking, and all 11 nodules were easily localized by means of thoracoscopy. The metallic coil showed the nodules on the fluoroscopic monitor, which aided in nodule manipulation. Nodules were completely resected under thoracoscopic guidance, except in one case in which a minithoracotomy was performed at an early stage of the trial. The pathologic diagnosis was primary adenocarcinoma in 9 patients, pulmonary metastasis from colon cancer in 1 patient, and pulmonary lymph node in 1 patient. Two cases of bronchioloalveolar adenocarcinoma with an invasive component and a well-differentiated adenocarcinoma were converted to open thoracotomy to perform curative lobectomy. CONCLUSIONS: In this pilot study computed tomography-guided transbronchial metallic coil marking with an ultrathin bronchoscope with virtual bronchoscopic simulation might be a useful method for the fluoroscopy-assisted thoracoscopic resection of pulmonary nodules. (Keyword) Adult / Aged / Aged, 80 and over / Bronchoscopes / Bronchoscopy / Female / Fluoroscopy / Humans / Lung Neoplasms / Male / Middle Aged / Pilot Projects / Reproducibility of Results / Thoracic Surgery, Video-Assisted / Thoracoscopy / Tomography, X-Ray Computed (Link to Publication Site) ● Publication site (DOI): 10.1016/j.jtcvs.2005.09.019 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 16515927 ● Search Scopus @ Elsevier (PMID): 16515927 ● Search Scopus @ Elsevier (DOI): 10.1016/j.jtcvs.2005.09.019 (DOI: 10.1016/j.jtcvs.2005.09.019, PubMed: 16515927)
145.	Haruhiko Fujino, Kazuya Kondo, Hisashi Ishikura, Hideo Maki, Hidetaka Kinoshita, Takanori Miyoshi, Yuji Takahashi, Naruhiko Sawada, Hiromitsu Takizawa, Taeko Nagao, Shoji Sakiyama and Yasumasa Monden : Matrix metalloproteinase inhibitor MMI-166 inhibits lymphogenous metastasis in an orthotopically implanted model of lung cancer, Molecular Cancer Therapeutics, Vol.4, No.9, 1409-1416, 2005. (Summary) Matrix metalloproteinases (MMP) are considered to be critically involved in tumor invasion and the metastasis of various cancers. MMI-166 is a selective inhibitor of matrix metalloproteinase (MMP-2, MMP-9, and MMP-14). The purpose of this study was to evaluate the effects of MMI-166 on both the growth of the implanted tumor and the lymph node metastasis of the mediastinum and prolonging the life span, using an orthotopic implantation model of the Ma44-3 cancer cell line. We examined the anti-invasive effect of MMI-166 in lung cancer cell lines using an in vitro invasion assay. Next, we examined the anticancer effect of MMI-166 in vivo. MMI-166 (200 mg/kg body weight) or a vehicle was administered orally to the orthotopically implanted lung cancer model. MMI-166 dose-dependently inhibited the invasion of cancer cell lines with expressions of MMP-2 and/or MMP-9 in vitro. In vivo, MMI-166 significantly inhibited mediastinal lymph node metastasis in this orthotopic model (weight of the mediastinum: control, 0.089 +/- 0.009 versus MMI-166, 0.069 +/- 0.008 mg; P = 0.005; metastatic area: control, 93,495 +/- 55,747 versus MMI-166, 22,747 +/- 17,478 pixels; P = 0.045). MMI-166 prolonged the life span by 6 days in median survival time in the orthotopically implanted model (P = 0.039). These results showed that MMI-166 could possibly inhibit lymph node metastasis and prolong the life span in lung cancer patients. (Keyword) Animals / Carcinoma, Non-Small-Cell Lung / Disease Models, Animal / Humans / Injections, Subcutaneous / Lung Neoplasms / Lymphatic Metastasis / Male / Matrix Metalloproteinases / Mice / Mice, SCID / Neoplasm Invasiveness / Neovascularization, Pathologic / Sulfonamides / Survival Rate / Tumor Cells, Cultured (Link to Publication Site) ● Publication site (DOI): 10.1158/1535-7163.MCT-05-0031 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 16170033 ● Search Scopus @ Elsevier (PMID): 16170033 ● Search Scopus @ Elsevier (DOI): 10.1158/1535-7163.MCT-05-0031 (DOI: 10.1158/1535-7163.MCT-05-0031, PubMed: 16170033)
146.	Kazuya Kondo, Takanori Miyoshi, Hiromitsu Takizawa, Koichiro Kenzaki, Shoji Sakiyama and Akira Tangoku : Photodynamic therapy for submucosal tumor of the central bronchus, The Journal of Medical Investigation : JMI, Vol.52, No.3,4, 208-211, 2005. (Summary) A 75-year-old man was referred to our hospital because of the emphysema and tumor of the right intermediate bronchus. Thoracic CT scan and bronchoscopic examination demonstrated a spherical tumor of the right intermediate bronchus covering a normal mucosa. The biopsy specimen obtained from this tumor was histologically diagnosed as "glandular type of adenocarcinoma in the bronchus". Surgical treatment was not feasible because of poor pulmonary function. Therefore, the patient underwent Photodynamic therapy (PDT) using porfimer sodium (Photofrin) and an excimer dye laser. After 4 months, the tumor disappeared and there has been no recurrence for 3 years 3 months. PDT can affect a submucosal tumor of the central airway, and is safe for patients with poor pulmonary function. Our report recommends that PDT should be applied not only to early lung cancer but also submucosal tumor of the central bronchus. (Keyword) photodynamic thera / lung cancer / submucosal tumor / central airway (Tokushima University Institutional Repository) ● Metadata: 110779 (Link to Publication Site) ● Publication site (DOI): 10.2152/jmi.52.208 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 16167540 ● Search Scopus @ Elsevier (PMID): 16167540 ● Search Scopus @ Elsevier (DOI): 10.2152/jmi.52.208 (Tokushima University Institutional Repository: 110779, DOI: 10.2152/jmi.52.208, PubMed: 16167540)
147.	Hiromitsu Takizawa, 中野基一郎, Koichiro Kenzaki, Kansei Komaki, Tadaoki Morimoto and Akira Tangoku : 甲状腺髄様癌術後肝転移に対し肝動脈化学塞栓療法が有効であった1例, Journal of Japan Surgical Association, Vol.66, No.7, 1709-1712, 2005. (Keyword) 甲状腺髄様癌 / 転移性肝癌 / 肝動脈化学塞栓療法 (Link to Publication Site) ● Publication site (DOI): 10.3919/jjsa.66.1709 (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1390001204849234560 ● Search Scopus @ Elsevier (DOI): 10.3919/jjsa.66.1709 (DOI: 10.3919/jjsa.66.1709, CiNii: 1390001204849234560)
148.	Shoji Sakiyama, Kazuya Kondo, Mitsuteru Yoshida, Hiromitsu Takizawa, Koichiro Kenzaki, Takanori Miyoshi, Masahiro Abe, Shingo Wakatsuki and Yasumasa Monden : Extramedullary plasmacytoma immunoglobulin D (λ) in the chest wall and the subglottic region, Journal of Thoracic and Cardiovascular Surgery, Vol.129, No.5, 1168-1169, 2005. (Keyword) Antineoplastic Combined Chemotherapy Protocols / Biopsy / Dexamethasone / Doxorubicin / Female / Glottis / Humans / Immunoglobulin D / Ki-67 Antigen / Laryngeal Neoplasms / Magnetic Resonance Imaging / Middle Aged / Neoplasms, Second Primary / Plasmacytoma / Prognosis / Radiotherapy, Adjuvant / Rare Diseases / Remission, Spontaneous / Thoracic Neoplasms / Thoracic Wall / Tomography, X-Ray Computed / Vincristine (Link to Publication Site) ● Publication site (DOI): 10.1016/j.jtcvs.2004.08.037 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 15867795 ● Search Scopus @ Elsevier (PMID): 15867795 ● Search Scopus @ Elsevier (DOI): 10.1016/j.jtcvs.2004.08.037 (DOI: 10.1016/j.jtcvs.2004.08.037, PubMed: 15867795)
149.	Haruhiko Fujino, Kazuya Kondo, Takanori Miyoshi, Hisashi Ishikura, Yuji Takahashi, Naruhiko Sawada, Yukiko Hirose, Hiromitsu Takizawa, Taeko Nagao, Shoji Sakiyama and Yasumasa Monden : Establishment of patient-like SCID mouse model by orthotopically implanting primary cultured cells from surgically-resected lung cancer tissues, Oncology Reports, Vol.10, No.6, 1709-1715, 2003. (Summary) In our previous studies, we established a lymphogenous metastatic SCID mouse model using orthotopic implantation of human lung cancer cell lines. However, the lymphogenous metastatic potential of each cell line in our models does not reflect that of a primary tumor. In this study, we made orthotopic implanted models using primary cultured cells from surgically-resected lung cancer tissues. Tissues of 5 patients with non-small cell lung cancer (NSCLC) were applied to a primary culture method using a collagen gel coated flask. Suspensions of 2.0x10(4) cancer cells were injected into the left lung of SCID mice. We could maintain primary culture cells from 2 (FM205 and FT821 cells) of 5 lung cancers, and made orthotopically implanted SCID mouse models. The size of both tumors in implanted sites of the lung increased with time. The FM205 cells microscopically were metastasized to the mediastinum by 4 weeks after implantation and macroscopically metastasized by 16 weeks. The FT821 cells were microscopically metastasized to the mediastinum by 4 weeks after implantation and macroscopically metastasized by 6 weeks. The lymphogenous metastatic potential of these primary culture cells was similar to that of clinical tumors. As the lymphogenous metastatic potential of this model reflects that of the clinical tumor, it is useful for elucidating the mechanism of lymphogenous metastasis and selecting anticancer drugs suitable for an individual patients. (Keyword) lung cancer / biology / Mediastinal Lymph Nodes / Non-Small Cell Lungg Cancer / Surgical Operation / Xenograft (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 14534683 ● Search Scopus @ Elsevier (PMID): 14534683 (PubMed: 14534683)
150.	Kazuya Kondo, Yuji Takahashi, Sumiyo Ishikawa, Hiroshi Uchihara, Yukiko Hirose, Kiyoshi Yoshizawa, Masaru Tsuyuguchi, Hiromitsu Takizawa, Takanori Miyoshi, Shoji Sakiyama and Yasumasa Monden : Microscopic analysis of chromium accumulation in the bronchi and lung of chromate workers, Cancer, Vol.98, No.11, 2420-2429, 2003. (Summary) It is known that chromium is an inhaled carcinogen and an important risk factor in the development of lung carcinoma. The authors used a microscopic X-ray fluorescence analyzer with transmitted X-ray mapping imaging (Horiba, Kyoto, Japan) to measure the accumulation of chromium in 10 resected lung tissue specimens and 90 biopsy specimens from chromate workers. The maximum chromium accumulation (mean +/- standard deviation) in 10 resected lung tissue specimens was 197 +/- 238 counts per second (cps)/mili ampere (mA) (range, 4-649 cps/mA). Chromium accumulation was scattered in six tissue specimens and diffuse in one specimen. Chromium accumulation in the proximal bronchi was less than in the bronchioles or subpleural regions of the lung. Chromium accumulation was detectable in 63 (70%) of 90 biopsy specimens, and the mean accumulation was 6.5 +/- 9.2 cps/mA (range, 0-46.5 cps/mA). Chromium detected in bronchial tissue specimens was deposited in the bronchial stroma but not in the epithelium. The maximum chromium accumulations in dysplasic (n = 3), squamous metaplastic (n = 10), and normal bronchial epithelia (n = 9) in chromate workers and in normal bronchial epithelia (n = 3) in non-chromate workers were 20.2 +/- 5.4, 18.3 +/- 12.2, 13.2 +/- 13.4, and 3.0 +/- 1.8 cps/mA, respectively. The amount of chromium accumulation significantly increased according to the progression of malignant change of the bronchial epithelium (P = 0.003). Previous studies found that lung carcinoma with chromate exposure exhibited a variety of genetic abnormalities. Considering genetic aberrations and chromium accumulation in these premalignant lesions is useful for elucidating the process of carcinogenesis in chromium-induced lung carcinoma. (Keyword) Chromium / accumulation / Lung Carcinoma / Chromate Worker / Bronchs / Lung Tissue Specimens (Link to Publication Site) ● Publication site (DOI): 10.1002/cncr.11818 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 14635077 ● Search Scopus @ Elsevier (PMID): 14635077 ● Search Scopus @ Elsevier (DOI): 10.1002/cncr.11818 (DOI: 10.1002/cncr.11818, PubMed: 14635077)

Academic Paper (Unrefereed Paper):

1.	Mitsuteru Yoshida, Shoji Sakiyama, Koichiro Kajiura, Hiroaki Toba, Yukikiyo Kawakami, Hiromitsu Takizawa, Kazuya Kondo and Akira Tangoku : Pulmonary Resection in Renal Cell Carcinoma Metastasis : the Influence of Histologic Atypia of the Metastatic Focus on Preoperative or Perioperative Diagnosis, The Japanese Journal of Thoracic Surgery, Vol.66, No.11, 996-999, 2013. (Keyword) 肺転移 / 腎細胞癌 / 組織学的異型度 / lung metastasis / renal cell carcinoma / degree of histologic atypia (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 24105116 ● CiNii @ National Institute of Informatics (CRID): 1390282763058427648 ● Summary page in Scopus @ Elsevier: 2-s2.0-84892415509 (PubMed: 24105116, CiNii: 1390282763058427648, Elsevier: Scopus)
2.	Hirokazu Takechi, 坂本晋一, 森下敦司, Masakazu Goto, 西野豪志, Yoshihito Furukita, Yota Yamamoto, Takahiro Yoshida, Jun-ichi Seike, Hiromitsu Takizawa and Akira Tangoku : Two patients managed by palliative care for symptoms due to cervical lymph node recurrence of esophageal carcinoma, Shikoku Acta Medica, Vol.69, No.3,4, 171-174, 2013. (Summary) Our department aggressively performs initial treatment for esophageal carcinoma with multidisciplinary approaches, and not only positively treats patients with recurrence or metastasis but also manages those in an advanced stage by following the wishes of patients and their families as much as possible. However, many patients with esophageal carcinoma develop digestive tract and tracheal problems with progression of the disease, and the palliation of symptoms and continuation of home care often become difficult. In such patients, it is important to secure and maintain the route of hydration and nutrition when oral fluid and food intake becomes difficult, and to control respiratory symptoms for the promotion of home care and palliation of symptoms in the terminal stage. In this report, we present 2 patients managed by palliative care until death while supporting home care by maintaining enteral nutrition using gastrostomy for esophageal narrowing due to cervical lymph node recurrence, and controlling the cough reflex and dyspnea associated with the development of a cervical lymph node-tracheal fistula through morphine hydrochloride administration. (Keyword) Palliative care / Home care / Esophageal carcinoma / Gastrostomy / Morphine (Tokushima University Institutional Repository) ● Metadata: 109632 (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1050564287418399360 (Tokushima University Institutional Repository: 109632, CiNii: 1050564287418399360)
3.	Shoji Sakiyama and Hiromitsu Takizawa : Redo operation for recurrent, disseminated and metastaic thymoma, The Japanese Journal of Thoracic Surgery, Vol.66, No.8, 721-726, 2013. (Summary) In this article, redo operation for recurrent thymoma was reviewed. Several cohort studies according the issues of the role of surgery for recurrent thymoma have been reported. Although these studies are of relatively small of seize and have selection biases, most of authors recommend surgical treatment for recurrent thymoma. Best results are expected in case of complete resection of the recurrence. Usually local recurrences are approached by a resternotomy, a clamshell incision or a hemi clamshell incision. Resternotomy associates with the risks of injury of brachiocepharic vein, heart and lungs and catastrophic hemorrhage. The degree of retrosternal adhesions and tumor invasion caused by recurrence are diverse. An oscillating saw is recommended for dividing the sternum. Video-assisted thoracic surgery(VATS)may help to dissect retrosternal adhesions. The most frequent pattern of recurrence is pleural implants after the initial operation with complete resection. In those cases, thoracotomy or VATS are often used. Redo operations for distant metastasis of thymoma are rare. Pleuropneumonectomy for pleural implantation is associated high morbidity and mortality rates, therefore this option is suitable for highly selected patients. Preoperative radiological evaluation of recurrent thymoma is important on planning of approach procedures. (Keyword) Humans / Neoplasm Metastasis / Neoplasm Recurrence, Local / Neoplasm Seeding / Reoperation / Thymoma / Thymus Neoplasms (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 23917192 ● Summary page in Scopus @ Elsevier: 2-s2.0-84893364024 (PubMed: 23917192, Elsevier: Scopus)

Proceeding of International Conference:

1.	Hiromitsu Takizawa : Mobile CBCT to guide endobronchial interventions A cost efficient but powerful option, The 22nd World Congress for Bronchology and Interventional Pulmonology (WCBIP), Oct. 2022.
2.	Seiya Inoue, Takahiro Yoshida, Masakazu Goto, Satoshi Fujiwara, INUI Tomohiro, Shin-ichi Sakamoto, Naoki Miyamoto, Mariko Aoyama, Hiroaki Toba and Hiromitsu Takizawa : The best method of the gastric tube reconstruction after esophagectomy, The International Society for Diseases of the Esophagus (VIRTUAL), Sep. 2022.
3.	K. Muguruma, Kazuya Kondo, R. Kishibuchi, Mitsuhiro Tsuboi, S. Soejima, B. Tegshee, Koichiro Kajiura, Yukikiyo Kawakami, Naoya Kawakita, Mitsuteru Yoshida, Hiromitsu Takizawa and Akira Tangoku : DNA Methylation of MT1A and NPTX2 Genes Predict Malignant Behavior of Thymic Epithelial Tumors, The IASLC 20th World Conference on Lung Cancer, Sep. 2019.
4.	S. Soejima, Kazuya Kondo, Mitsuhiro Tsuboi, R. Kishibuchi, K. Muguruma, B. Tegshee, Koichiro Kajiura, Yukikiyo Kawakami, Naoya Kawakita, Mitsuteru Yoshida, Hiromitsu Takizawa, Akira Tangoku and N. Wusiman : GAD1 Expression and Its Methylation Become Indicators of Malignant Behavior in Thymic Epithelial Tumor, The IASLC 20th World Conference on Lung Cancer, Sep. 2019.
5.	Hiromitsu Takizawa, Toru Sawada, Mika Takashima, Daisuke Matsumoto, Naoya Kawakita, Mitsuhiro Tsuboi, Hiroaki Toba, Mitsuteru Yoshida, Yukikiyo Kawakami, Kazuya Kondo and Akira Tangoku : Autofluorescence Mode of Thoracoscope Improves Visceral Pleural Invasion Diagnosis in Non-Small Cell Lung Cancer, 19th World Conference on Lung Cancer, Sep. 2018.
6.	Naoya Kawakita, Hiromitsu Takizawa, Ali Eman, Mika Takashima, Daisuke Matsumoto, Toru Sawada, Mitsuhiro Tsuboi, Hiroaki Toba, Mitsuteru Yoshida, Yukikiyo Kawakami, Kazuya Kondo and Akira Tangoku : Cone-Beam CT Confirms the Status of Transbronchial Biopsy Under Virtual Bronchoscopic Navigation for Peripheral Lung Lesions, 19th World Conference on Lung Cancer, Sep. 2018.
7.	Hiromitsu Takizawa, Mika Takashima, Daisuke Matsumoto, Naoya Kawakita, Toru Sawada, Mitsuhiro Tsuboi, Hiroaki Toba, Mitsuteru Yoshida, Yukikiyo Kawakami, Kazuya Kondo and Akira Tangoku : CT and PET/CT Parameters of Lepidic Predominant Pattern Lung Adenocarcinoma and Invasiveness on Pathology, 19th World Conference on Lung Cancer, Sep. 2018.
8.	Kazuya Kondo, Soejima Shiho, wusiman nuliamina, Kishibuchi Reina, Mitsuhiro Tsuboi, Koichiro Kajiura, Yukikiyo Kawakami, Naoya Kawakita, Toru Sawada, Hiroaki Toba, Mitsuteru Yoshida, Hiromitsu Takizawa and Akira Tangoku : The expression of DNA methylation of GAD1 gene is an indicator of malignant behavior in thymic epithelial tumor, 19th World Conference on Lung Cancer, Sep. 2018.
9.	澤田徹, Kazuya Kondo, Mitsuhiro Tsuboi, Naoya Kawakita, Koichiro Kajiura, Hiroaki Toba, Yukikiyo Kawakami, Mitsuteru Yoshida, Hiromitsu Takizawa and Akira Tangoku : FDG-PET/CT Might Be a Predictor for Residual Disease in Advanced NSCLC after Chemoradiotherapy, 17th World Conference on Lung Cancer, Dec. 2016.
10.	Naoya Kawakita, Hiroaki Toba, 澤田徹, Mitsuhiro Tsuboi, Koichiro Kajiura, Yukikiyo Kawakami, Mitsuteru Yoshida, Hiromitsu Takizawa, Kazuya Kondo and Akira Tangoku : Stratification of pStage I Lung Adenocarcinoma by the Scoring System Based on Prognostic Factors, 17th World Conference on Lung Cancer, Dec. 2016.
11.	Mitsuhiro Tsuboi, Kazuya Kondo, Koichiro Kajiura, Hiromitsu Takizawa, 澤田徹, Naoya Kawakita, Hiroaki Toba, Yukikiyo Kawakami, Mitsuteru Yoshida and Akira Tangoku : Promoter Hypermethylation of DNA Mismatch Repair Gene hMLH1 of Lung Cancer in Chromate-Exposed Workers, 17th World Conference on Lung Cancer, Dec. 2016.
12.	Koichiro Kajiura, Kazuya Kondo, 澤田徹, Naoya Kawakita, Mitsuhiro Tsuboi, Hiromitsu Takizawa and Akira Tangoku : The Relationship of CDH3 Expression and DNA Methylation in Thymic Epitherial Tumors, 17th World Conference on Lung Cancer, Dec. 2016.
13.	Tamaki Otani, Kazuya Kondo, Hiromitsu Takizawa, Koichiro Kajiura, Fujino Haruhiko and Hideki Otsuka : Non-Invasive Assessment of Cisplatin and Erlotinib Efficacy in Lung Cancer by Monitoring an Orthotopic SCID Mouse Model with Computed Tomography, 16th World Conference on Lung Cancer, Sep. 2015.
14.	Koichiro Kajiura, Kazuya Kondo, 松本大資, 河北直也, Mitsuhiro Tsuboi, Hiroaki Toba, Yukikiyo Kawakami, Hiromitsu Takizawa, Shoji Sakiyama and Akira Tangoku : DNA Methylation on Promotor Region of RASSF1 Gene in Thymic Neuroendocrine Tumor Is Higher than B3 Thymoma and Thymic Squamous Cell Carcinoma, 16th World Conference on Lung Cancer, Sep. 2015.
15.	Mitsuhiro Tsuboi, Hiromitsu Takizawa, Daisuke Matsumoto, Naoya Kawakita, Koichiro Kajiura, Hiroaki Toba, Yukikiyo Kawakami, Shoji Sakiyama, Kazuya Kondo and Akira Tangoku : The Correlation between Visceral Pleural Invasion in T1a Non-Small Lung Cancer and Lymph Node Metastasis, 16th World Conference on Lung Cancer, Sep. 2015.
16.	Kazuya Kondo, Tomoko Kawanishi, Mariko Shiraishi, Chikako Takai, Yuki Morimoto, Tamaki Otani, Mitsuhiro Tsuboi, Koichiro Kajiura, Hiromitsu Takizawa, Gokei Kawakami, Hiroaki Toba, Shoji Sakiyama and Akira Tangoku : The MRE11/RAD50/NBS1 Complex Was Impaired in Lung Cancer from Chromate-Exposed Workers, 16th World Conference on Lung Cancer, Sep. 2015.
17.	Hiromitsu Takizawa, Kazuya Kondo, Mitsuhiro Tsuboi, Koichiro Kajiura, Tamaki Otani, Hiroaki Toba, Yukikiyo Kawakami, Shoji Sakiyama and Akira Tangoku : Mini OralComputed Tomography Lymphography by Transbronchial Injection of Iopamidol for Preoperative, 16th World Conference on Lung Cancer, Sep. 2015.
18.	Tamaki Otani, Hideki Otsuka, Kazuya Kondo, Hiromitsu Takizawa and Nagata Motoi : Utility of respiratory-gated PET/CT in the chronological evaluation of an orthotopic lung cancer transplantation mouse model, Annual Congress of the European Association of Nuclear Medicine, Oct. 2014.
19.	Mitsuteru Yoshida, Shoji Sakiyama, 日野弘之, 高嶋美佳, Mitsuhiro Tsuboi, Koichiro Kajiura, Hiroaki Toba, Yasushi Nakagawa, Yukikiyo Kawakami, Hiromitsu Takizawa, Kazuya Kondo and Akira Tangoku : Anatomical Anomaly Cases Of General Thoracic Surgery, American Thoracic Society International Conference2014, San Diego, May 2014.
20.	Shoji Sakiyama, Mitsuteru Yoshida, Yukikiyo Kawakami, Koichiro Kenzaki, Mitsuhiro Tsuboi, Koichiro Kajiura, Yasushi Nakagawa, Hiromitsu Takizawa, Kazuya Kondo and Akira Tangoku : Glucocorticoid Administration Facilitates The Differentiation Of Rat Fetal Lung Fragments Into Adult Rat Lung Parenchyma, American Thoracic Society International Conference2014, San Diego, California, May 2014.
21.	Koichiro Kajiura, Shoji Sakiyama, Hiromitsu Takizawa, Yasushi Nakagawa, Kazuya Kondo and Akira Tangoku : Prophylactic landiolol administration can prevent atrial fibrillation after lobectomy?, 15th World Conference on Lung Cancer, Oct. 2013.
22.	Hiromitsu Takizawa, Kazuya Kondo, Tamaki Otani, Ali M. Mohammed, Hideki Otsuka, Mitsuhiro Tsuboi, Koichiro Kajiura, Yasushi Nakagawa, Yukikiyo Kawakami, Mitsuteru Yoshida, Shoji Sakiyama and Akira Tangoku : Positron-emission tomography-computed tomography with the glucose analogue [18F] fluorodeoxyglucose in orthotopic implantation SCID mouse model of lung cancer, 15th World Conference on Lung Cancer, Oct. 2013.
23.	Mitsuhiro Tsuboi, Hiromitsu Takizawa, Kazuya Kondo, Hisashi Ishikura, Suguru Kimura, Koichiro Kajiura, Yasushi Nakagawa, Yukikiyo Kawakami, Mitsuteru Yoshida, Shoji Sakiyama and Akira Tangoku : A feasibility study of postoperative adjuvant chemotherapy with fluoropyrimidine S-1 in patients with stage II-IIIA non-small cell lung cance, 15th World Conference on Lung Cancer, Oct. 2013.
24.	Hiromitsu Takizawa, Kazuya Kondo, Hiroaki Toba, Koichiro Kajiura, Mayumi Ikeda, Takako Furukawa, Takeshi Nishino, Yasushi Nakagawa, Mitsuteru Yoshida, Yukikiyo Kawakami, Shoji Sakiyama and Akira Tangoku : PREOPERATIVE AND INTRAOPERATIVE IDENTIFICATION OF SENTINEL NODES IN PATIENTS, THE 21ST ANNUAL MEETING OF THE ASIAN SOCIETY FOR CARDIOVASCULAR AND THORACIC, Apr. 2013.
25.	Takae Bando, Chiemi Onishi, 山田和代, Kazuya Kondo, Yoshie Imai, Keiko Mori, Shoji Sakiyama and Hiromitsu Takizawa : Acute sholder symptoms and related factors in patients undergoing lung cancer surgery, Prague, Sep. 2012.
26.	Y. Fujita, Kazuya Kondo, A.H.K. Ali, T. Namura, Y. Senba, Y. Oiwa, C. Takai, Hiromitsu Takizawa, Yasushi Nakagawa, Hiroaki Toba, Koichiro Kenzaki, Shoji Sakiyama and Akira Tangoku : Polymorphisms in x-ray repair cross-complementing group 1 (XRCC1) base excision repair gene and lung cancer risk in industrial workers with chromate exposure, 14TH WORLD CONFERENCE ON LUNG CANCER, Jul. 2011.
27.	A.H.K. Ali, Hiromitsu Takizawa, Kazuya Kondo, Yasushi Nakagawa, Hiroaki Toba, N. Khasag, Koichiro Kenzaki, Shoji Sakiyama and Akira Tangoku : Follow- up using fluorescence bronchoscopy for the patients with photodynamic therapy treated early lung cancer, 14TH WORLD CONFERENCE ON LUNG CANCER, Jul. 2011.
28.	M. Takashima, Hiromitsu Takizawa, K. Kajiura, K. Uyama, Hiroaki Toba, Yasushi Nakagawa, Yukikiyo Kawakami, Koichiro Kenzaki, Shoji Sakiyama, Kazuya Kondo and Akira Tangoku : Comparison of two different EGFR gene mutation tests for resected lung adenocarcinoma, 14TH WORLD CONFERENCE ON LUNG CANCER, Jul. 2011.
29.	K. Kajiura, Hiroaki Toba, Shoji Sakiyama, M. Takashima, K. Uyama, Yasushi Nakagawa, Hiromitsu Takizawa, Yukikiyo Kawakami, Koichiro Kenzaki, Kazuya Kondo and Akira Tangoku : Experience of TBLB using thin bronchoscopy with VBN, 14TH WORLD CONFERENCE ON LUNG CANCER, Jul. 2011.
30.	H. Matsuoka, Kazuya Kondo, Hiromitsu Takizawa, H. Fujino, K. Uyama, Hiroaki Toba, Koichiro Kenzaki, Shoji Sakiyama and Akira Tangoku : Comprehensive evaluation of the responded genes by the administration of anti-tumor drug, S-1 using low, 14TH WORLD CONFERENCE ON LUNG CANCER, Jul. 2011.
31.	Hiromitsu Takizawa, Kazuya Kondo, Hiroaki Toba, K. Kajiura, M. Takashima, K. Uyama, Yasushi Nakagawa, Yukikiyo Kawakami, Koichiro Kenzaki, Shoji Sakiyama and Akira Tangoku : Computed tomography lymphography by transbronchial injection of a water-soluble extracellular CT, 14TH WORLD CONFERENCE ON LUNG CANCER, Jul. 2011.
32.	Khalil Hamed Abdellah, Hiromitsu Takizawa, Kazuya Kondo, Matsuoka Hisashi, Hiroaki Toba, Yasushi Nakagawa, Koichiro Kenzaki, Shoji Sakiyama, Kakiuchi Soji, Saburo Sone and Akira Tangoku : In vitro and in vivo photodynamic diagnosis using 5-aminolevulinic acid in malignant mesothelioma, The 10th International Conference of the International Mesothelioma Interest Group, Aug. 2010.

Proceeding of Domestic Conference:

1.	Masakazu Goto, Seiya Inoue, 細川暉雄, 髙杉遥, Atsushi Morishita, Satoshi Fujiwara, Hiroaki Toba and Hiromitsu Takizawa : 切除不能進行・再発食道癌に対するICIを組み入れた治療戦略の安全性と有効性について, 第110回日本消化器病学会総会, May 2024.
2.	Masakazu Goto, Seiya Inoue, 細川暉雄, 髙杉遥, Atsushi Morishita, Satoshi Fujiwara, Hiroaki Toba and Hiromitsu Takizawa : 当科における食道癌に対するICI投与の現状について∼術後補助と切除不能・再発症例における安全性と治療効果について∼, 第124回日本外科学会定期学術集会, Apr. 2024.
3.	Seiya Inoue, Masakazu Goto, Satoshi Fujiwara, 細川暉雄, Taihei Takeuchi, 髙杉遥, Shin-ichi Sakamoto, Hiroyuki Sumitomo, Naoki Miyamoto, Atsushi Morishita, Mariko Aoyama, Naoya Kawakita, Hiroaki Toba and Hiromitsu Takizawa : 地方大学において外科医不足を補うために∼特定看護師の役割∼, 第124回日本外科学会定期学術集会, Apr. 2024.
4.	Mariko Aoyama, Seiya Inoue, 細川暉雄, Taihei Takeuchi, Shin-ichi Sakamoto, Hiroyuki Sumitomo, Naoki Miyamoto, Atsushi Morishita, Satoshi Fujiwara, Masakazu Goto, Hiroaki Toba and Hiromitsu Takizawa : 縦隔内甲状腺・副甲状腺腫瘍に対する縦隔鏡手術の有用性, 第124回日本外科学会定期学術集会, Apr. 2024.
5.	Koichi Tomita, Teruyoshi Hirayama, Hiroki Umeshima, Koichi Tsuneyama, Akiyoshi Nishimura, Hideyuki Nushida, Masashi Akaike, Hiromitsu Takizawa, Mitsuo Shimada, Yasushi Takagi, Ichiro Hashimoto and Takashi Iwata : 徳島大学医学部の系統解剖実習における画像診断技術・病理診断技術・外科的手術手技を取り入れた垂直連携教育の実践, 第129回日本解剖学会全国学術集会, Mar. 2024.
6.	竹内大平, Hiromitsu Takizawa, 細川暉雄, Hiroyuki Sumitomo, Naoki Miyamoto, Shin-ichi Sakamoto, Atsushi Morishita, Naoya Kawakita, Hiroaki Toba and Kazuya Kondo : 肺転移をきたしたA型胸腺腫の3例, 第43回日本胸腺研究会, Feb. 2024.
7.	杉本花奈乃, Hiroaki Inoue, Souichiro Sasa, Tomohiro Inui, 行重佐和香, Mariko Aoyama, Hiroaki Toba, Masakazu Goto, Yoshimi Bando and Hiromitsu Takizawa : 乳頭の硬結で発見された浸潤性小葉癌の1例, 第33回日本乳癌検診学会学術総会, Nov. 2023.
8.	行重佐和香, Hiroaki Inoue, Tomohiro Inui, Souichiro Sasa, Mariko Aoyama, Takeshi Oya, Yoshimi Bando, Masakazu Goto and Hiromitsu Takizawa : 乳腺原発神経内分泌腫瘍の1例, 第33回日本乳癌検診学会学術総会, Nov. 2023.
9.	竹内大平, Hiromitsu Takizawa, 細川暉雄, Hiroyuki Sumitomo, Naoki Miyamoto, Shin-ichi Sakamoto, Atsushi Morishita, Naoya Kawakita, Hiroaki Toba and Kazuya Kondo : ロボット支援手術が完全切除に有用であったIgG4関連後縦隔腫瘍の1例, 第85回日本臨床外科学会総会, Nov. 2023.
10.	細川暉雄, Mariko Aoyama, 竹内大平, 髙杉遥, Shin-ichi Sakamoto, Hiroyuki Sumitomo, Naoki Miyamoto, Atsushi Morishita, Seiya Inoue, Satoshi Fujiwara, Masakazu Goto, Hiroaki Toba and Hiromitsu Takizawa : Dynamic CTにより残存腺腫を同定した原発性副甲状腺機能亢進症の1例, 第85回日本臨床外科学会総会, Nov. 2023.
11.	Mariko Aoyama, 細川暉雄, 竹内大平, 髙杉遥, Shin-ichi Sakamoto, Hiroyuki Sumitomo, Naoki Miyamoto, Atsushi Morishita, Seiya Inoue, Satoshi Fujiwara, Masakazu Goto, Hiroaki Toba and Hiromitsu Takizawa : 当科における中リスク甲状腺乳頭癌における治療成績に関する検討, 第85回日本臨床外科学会総会, Nov. 2023.
12.	Seiya Inoue, Masakazu Goto, Satoshi Fujiwara, 細川暉雄, 竹内大平, Hiroyuki Sumitomo, Naoki Miyamoto, Shin-ichi Sakamoto, Atsushi Morishita, Mariko Aoyama, Naoya Kawakita, Hiroaki Toba, Hiromitsu Takizawa and Yoshihiro Tsuruo : 縦隔鏡下食道切除術を安全に行うためのトレーニング, 第85回日本臨床外科学会総会, Nov. 2023.
13.	Hiroaki Toba, 細川暉雄, 竹内大平, Shin-ichi Sakamoto, Hiroyuki Sumitomo, Naoki Miyamoto, Mika Takashima, Naoya Kawakita, Hiromitsu Takizawa, Yoshihiro Tsuruo and Takeshige Otoi : 手術トレーニング施設を目的別に有効活用してシュミレーションする，若手呼吸器外科医のための高難度手術教育, 第85回日本臨床外科学会総会, Nov. 2023.
14.	Yuki Tsukazaki, Makoto Tobiume, Atsushi Mitsuhashi, Ryohiko Ozaki, Yohei Yabuki, Hiroto Yoneda, Hirokazu Ogino, Masaki Hanibuchi, Hirohisa Ogawa, Hiromitsu Takizawa and Yasuhiko Nishioka : 非小細胞肺癌症例における腫瘍浸潤線維細胞の走化因子と疾患予後との関連性についての解析, 第64回日本肺癌学会学術集会, Nov. 2023.
15.	Takae Bando, Kazuya Kondo, 植地日菜子, 荒尾心喜, 尾形京香, Aki Takahashi, Yoshie Imai, Yuta Inoue, Yuka Mori and Hiromitsu Takizawa : 肺がん患者の術前のレジリエンス，心理的適応および健康関連QOL(第1報), 第64回日本肺癌学会学術集会, Nov. 2023.
16.	Munkhjargal Batkhishig, Kazuya Kondo, Soejima Shiho, Tegshee Bilguun, Naoya Kawakita, Hiroaki Toba and Hiromitsu Takizawa : Prognostic significance of PEAR1 expression in lung adenocarcinoma, 第64回日本肺癌学会学術集会, Nov. 2023.
17.	Atsushi Morishita, Naoya Kawakita, 細川暉雄, Taihei Takeuchi, Shin-ichi Sakamoto, Hiroyuki Sumitomo, Naoki Miyamoto, Hiroaki Toba, Kazuya Kondo and Hiromitsu Takizawa : Invasive mucinous adenocarcinomaにおける術前経気管支生検が及ぼす予後への影響, 第64回日本肺癌学会学術集会, Nov. 2023.
18.	Naoki Miyamoto, Mitsuteru Yoshida, 細川暉雄, Taihei Takeuchi, 髙杉遥, Hiroyuki Sumitomo, Shin-ichi Sakamoto, Atsushi Morishita, Naoya Kawakita, Kazuya Kondo, Hiroaki Toba and Hiromitsu Takizawa : アルギニンおよびシトルリンは免疫治療の補助薬となり得るか, 第64回日本肺癌学会学術集会, Nov. 2023.
19.	Hiroyuki Sumitomo, Hiroaki Toba, 細川暉雄, Taihei Takeuchi, 髙杉遥, Shin-ichi Sakamoto, Naoki Miyamoto, Atsushi Morishita, Naoya Kawakita, Kazuya Kondo and Hiromitsu Takizawa : 小型末梢肺病変に対する気管支鏡下コイルマーキング法の現状, 第64回日本肺癌学会学術集会, Nov. 2023.
20.	Naoya Kawakita, 細川暉雄, Taihei Takeuchi, Hiroyuki Sumitomo, Naoki Miyamoto, Shin-ichi Sakamoto, Atsushi Morishita, Kazuya Kondo, Hiroaki Toba and Hiromitsu Takizawa : 精密な生検を目指したCone-beam CTガイド下極細径気管支鏡下生検∼Augmented Fluoroscopyで見える化する∼, 第64回日本肺癌学会学術集会, Nov. 2023.
21.	ZHANG LIN WAN, Kazuya Kondo, Takae Bando, Aki Takahashi, Yoshie Imai, Mika Takashima, Shin-ichi Sakamoto, Naoki Miyamoto, Naoya Kawakita, Yukikiyo Kawakami, Mitsuteru Yoshida, Hiroaki Toba and Hiromitsu Takizawa : 高齢者機能評価を用いた癌患者の治療方針の決定(第二報), 第64回日本肺癌学会学術集会, Nov. 2023.
22.	Shin-ichi Sakamoto, Naoya Kawakita, 細川暉雄, Taihei Takeuchi, Hiroyuki Sumitomo, Naoki Miyamoto, Atsushi Morishita, Hiroaki Toba, Kazuya Kondo and Hiromitsu Takizawa : 予後因子に基づいた間質性肺炎合併肺癌に対する治療戦略, 第76回日本胸部外科学会定期学術集会, Oct. 2023.
23.	Taihei Takeuchi, Naoya Kawakita, 細川暉雄, Hiroyuki Sumitomo, Naoki Miyamoto, Shin-ichi Sakamoto, Atsushi Morishita, Hiroaki Toba, Kazuya Kondo and Hiromitsu Takizawa : 早期肺腺癌における炎症マーカーと予後に関する検討, 第76回日本胸部外科学会定期学術集会, Oct. 2023.
24.	阿部祐也, Hiroaki Inoue, Souichiro Sasa, Mariko Aoyama, Tomohiro Inui, 行重佐和香, Kazumasa Okumura, Naoki Miyamoto, Masakazu Goto, Hiroaki Toba, Takashi Kawanaka and Hiromitsu Takizawa : 顔面のしびれを契機に発見された頭蓋底骨転移に対し放射線治療が有効であった1例, 第20回日本乳癌学会中国四国地方会, Sep. 2023.
25.	細川暉雄, Tomohiro Inui, Sawaka Yukishige, Souichiro Sasa, Mariko Aoyama, Hiroaki Inoue, Hiroaki Toba and Hiromitsu Takizawa : 有害事象マネジメントにより術前ペムブロリズマブ投与を継続しpCRの診断を得たトリプルネガティブ乳癌の1例, 第20回日本乳癌学会中国四国地方会, Sep. 2023.
26.	Hiroyuki Sumitomo, Hiroaki Toba, 細川暉雄, Taihei Takeuchi, Shin-ichi Sakamoto, Naoki Miyamoto, Atsushi Morishita, Naoya Kawakita, Kazuya Kondo and Hiromitsu Takizawa : ICG蛍光ガイド下に胸腔鏡下肺区域切除術を施行した肝細胞癌肺転移の1例, 日本蛍光ガイド手術研究会第6回学術集会, Sep. 2023.
27.	Seiya Inoue, Masakazu Goto, Satoshi Fujiwara, 細川暉雄, Taihei Takeuchi, 髙杉遥, Shin-ichi Sakamoto, Hiroyuki Sumitomo, Naoki Miyamoto, Atsushi Morishita, Mariko Aoyama, Naoya Kawakita, Hiroaki Toba and Hiromitsu Takizawa : ICG胃管血流評価を意識した食道胃管吻合の取り組み, 日本蛍光ガイド手術研究会第6回学術集会, Sep. 2023.
28.	Hiromitsu Takizawa, 細川暉雄, Taihei Takeuchi, Shin-ichi Sakamoto, Hiroyuki Sumitomo, Naoki Miyamoto, Atsushi Morishita, Naoya Kawakita, Hiroaki Toba and Kazuya Kondo : 肺切除におけるICG蛍光による術中気管支動脈可視化の意義, 日本蛍光ガイド手術研究会第6回学術集会, Sep. 2023.
29.	Sawaka Yukishige, Hiroaki Inoue, Tomohiro Inui, Naoki Miyamoto, Souichiro Sasa, Mariko Aoyama, Masakazu Goto, Hiroaki Toba and Hiromitsu Takizawa : 高Ca血症のコントロールに難渋した乳癌多発骨転移の1例, 第98回中国四国外科学会総会/第28回中国四国内視鏡外科研究会, Aug. 2023.
30.	Naoki Miyamoto, Mariko Aoyama, 井﨑富由実, Taihei Takeuchi, Hiroyuki Sumitomo, Shin-ichi Sakamoto, Seiya Inoue, Satoshi Fujiwara, Naoya Kawakita, Masakazu Goto, Hiroaki Toba and Hiromitsu Takizawa : レンバチニブ投与により難治性気胸を発症した甲状腺未分化癌の一例, 第98回中国四国外科学会総会/第28回中国四国内視鏡外科研究会, Aug. 2023.
31.	Satoshi Fujiwara, Sawaka Yukishige, Taihei Takeuchi, 髙杉遥, Hiroyuki Sumitomo, Atsushi Morishita, Seiya Inoue, Masakazu Goto, Hiroaki Toba and Hiromitsu Takizawa : 食道癌手術における胃管作成に対する術式の検討, 第98回中国四国外科学会総会/第28回中国四国内視鏡外科研究会, Aug. 2023.
32.	Taihei Takeuchi, Naoya Kawakita, 細川暉雄, Hiroyuki Sumitomo, Naoki Miyamoto, Shin-ichi Sakamoto, Atsushi Morishita, Hiroaki Toba, Kazuya Kondo and Hiromitsu Takizawa : 術前に診断が困難であったアスペルギローマ合併肺癌の1例, 第98回中国四国外科学会総会/第28回中国四国内視鏡外科研究会, Aug. 2023.
33.	Hiroaki Inoue, Souichiro Sasa, Mariko Aoyama, Tomohiro Inui, Sawaka Yukishige, Naoki Miyamoto, Hiroaki Toba, Masakazu Goto and Hiromitsu Takizawa : 高齢乳癌患者におけるCDK4/6阻害剤投与の検討, 第98回中国四国外科学会総会/第28回中国四国内視鏡外科研究会, Aug. 2023.
34.	Mariko Aoyama, 細川暉雄, Taihei Takeuchi, Shin-ichi Sakamoto, Hiroyuki Sumitomo, Naoki Miyamoto, Seiya Inoue, Satoshi Fujiwara, Masakazu Goto, Hiroaki Toba and Hiromitsu Takizawa : 当科における進行・再発甲状腺癌に対するレンバチニブの使用経験と今後の治療戦略, 第98回中国四国外科学会総会/第28回中国四国内視鏡外科研究会, Aug. 2023.
35.	Shin-ichi Sakamoto, Hiromitsu Takizawa, 細川暉雄, Taihei Takeuchi, Hiroyuki Sumitomo, Naoki Miyamoto, Atsushi Morishita, Naoya Kawakita, Hiroaki Toba and Kazuya Kondo : 当院における複雑区域切除への取り組み, 第98回中国四国外科学会総会/第28回中国四国内視鏡外科研究会, Aug. 2023.
36.	Shin-ichi Sakamoto, Hiromitsu Takizawa, 細川暉雄, Taihei Takeuchi, Hiroyuki Sumitomo, Naoki Miyamoto, Naoya Kawakita, Hiroaki Toba and Kazuya Kondo : 右下葉切除後に残存中葉切除を施行した一例, 第61回日本肺癌学会中国四国支部会, Jul. 2023.
37.	Mika Takashima, Hiroaki Toba, 井﨑富由実, Taihei Takeuchi, Shin-ichi Sakamoto, Hiroyuki Sumitomo, Naoki Miyamoto, Naoya Kawakita, Yukikiyo Kawakami, Kazuya Kondo and Hiromitsu Takizawa : 感染を背景とした肺葉内の仮性動脈瘤に対し肺葉切除で救命した1例, 第40回日本呼吸器外科学会学術集会, Jul. 2023.
38.	井﨑富由実, Hiroaki Toba, Taihei Takeuchi, Hiroyuki Sumitomo, Naoki Miyamoto, Shin-ichi Sakamoto, Mika Takashima, Naoya Kawakita, Kazuya Kondo and Hiromitsu Takizawa : 対照的な術後経過をたどった胸管嚢胞の2切除例, 第40回日本呼吸器外科学会学術集会, Jul. 2023.
39.	Shin-ichi Sakamoto, Hiroaki Toba, Hiromitsu Takizawa, 井﨑富由実, Taihei Takeuchi, Hiroyuki Sumitomo, Naoki Miyamoto, Mika Takashima, Naoya Kawakita, Yukikiyo Kawakami, Kazuya Kondo, Yoshihiro Tsuruo and Takeshige Otoi : U-40呼吸器外科医が高難度手術手技を習得するための取り組み, 第40回日本呼吸器外科学会学術集会, Jul. 2023.
40.	Hiroyuki Sumitomo, Naoya Kawakita, 井﨑富由実, Taihei Takeuchi, Shin-ichi Sakamoto, Naoki Miyamoto, Mika Takashima, Yukikiyo Kawakami, Hiroaki Toba, Kazuya Kondo and Hiromitsu Takizawa : 術前肺動脈径は肺癌術後の予後因子となり得る, 第40回日本呼吸器外科学会学術集会, Jul. 2023.
41.	Naoki Miyamoto, Mitsuteru Yoshida, 井﨑富由実, Taihei Takeuchi, Hiroyuki Sumitomo, Shin-ichi Sakamoto, Mika Takashima, Naoya Kawakita, Yukikiyo Kawakami, Kazuya Kondo, Hiroaki Toba and Hiromitsu Takizawa : アルギニン+シトルリンはPD-1阻害薬による抗腫瘍効果を増強する, 第40回日本呼吸器外科学会学術集会, Jul. 2023.
42.	Hiroaki Toba, Hiroyuki Sumitomo, 井﨑富由実, Taihei Takeuchi, Shin-ichi Sakamoto, Naoki Miyamoto, Mika Takashima, Naoya Kawakita, Kazuya Kondo and Hiromitsu Takizawa : 大きな縦隔腫瘍に対する気縦隔を用いた縦隔鏡アプローチ∼食道外科医との合同手術, 第40回日本呼吸器外科学会学術集会, Jul. 2023.
43.	Naoya Kawakita, Hiroaki Toba, 井﨑富由実, Taihei Takeuchi, Shin-ichi Sakamoto, Hiroyuki Sumitomo, Naoki Miyamoto, Mika Takashima, Yukikiyo Kawakami, Kazuya Kondo and Hiromitsu Takizawa : 遷延性肺瘻のリスクスコアに基づく治療介入決定はドレーン留置期間を短縮させる, 第40回日本呼吸器外科学会学術集会, Jul. 2023.
44.	Hiromitsu Takizawa : 《ランチョンセミナー》気管支断端の血流を意識した肺葉切除, 第40回日本呼吸器外科学会学術集会, Jul. 2023.
45.	Masakazu Goto, 井﨑富由実, Sawaka Yukishige, Taihei Takeuchi, Hiroyuki Sumitomo, Satoshi Fujiwara, Seiya Inoue and Hiromitsu Takizawa : 当科における高齢者食道癌患者に対する治療戦略と予後について, 第78回日本消化器外科学会総会, Jul. 2023.
46.	Satoshi Fujiwara, 井﨑富由実, Taihei Takeuchi, Hiroyuki Sumitomo, Seiya Inoue, Masakazu Goto and Hiromitsu Takizawa : 食道癌手術における胃管作成に対する術式の検討, 第77回日本食道学会学術集会, Jun. 2023.
47.	Seiya Inoue, Masakazu Goto, Satoshi Fujiwara, 井﨑富由実, Taihei Takeuchi, Hiroyuki Sumitomo, Shin-ichi Sakamoto, Naoki Miyamoto, Mariko Aoyama, Hiroaki Toba and Hiromitsu Takizawa : NAC後の術後補助化学療法の有用性の検討, 第77回日本食道学会学術集会, Jun. 2023.
48.	Masakazu Goto, 井﨑富由実, Sawaka Yukishige, Taihei Takeuchi, Hiroyuki Sumitomo, Mariko Aoyama, Satoshi Fujiwara, Seiya Inoue, Hiroaki Toba and Hiromitsu Takizawa : 当院における高齢者食道癌患者に対する治療と予後について, 第77回日本食道学会学術集会, Jun. 2023.
49.	Tomohiro Inui, Hiroaki Inoue, Souichiro Sasa, Kazumasa Okumura, Mariko Aoyama, Sawaka Yukishige, 井﨑富由実, Naoki Miyamoto, Hiroaki Toba, Yoshimi Bando and Hiromitsu Takizawa : 当院における肉芽腫性乳腺炎治療の検討, 第31回日本乳癌学会学術総会, Jun. 2023.
50.	Sawaka Yukishige, Tomohiro Inui, Souichiro Sasa, Mariko Aoyama, Hiroaki Inoue, Kazumasa Okumura, Masakazu Goto, Hiroaki Toba, Hiromitsu Takizawa, 甫喜本憲弘 and 頼田顕辞 : 局所皮弁による再建を行った腋窩副乳癌の1例, 第31回日本乳癌学会学術総会, Jun. 2023.
51.	Mariko Aoyama, Hiroaki Inoue, Tomohiro Inui, Souichiro Sasa, Kazumasa Okumura, Masakazu Goto, Hiroaki Toba and Hiromitsu Takizawa : トリプルネガティブ乳癌におけるHER2低発現の有無による臨床病理学的所見と予後の検討, 第31回日本乳癌学会学術総会, Jun. 2023.
52.	Hiroaki Inoue, Souichiro Sasa, Kazumasa Okumura, Mariko Aoyama, Tomohiro Inui, Sawaka Yukishige, 井﨑富由実, Naoki Miyamoto, Hiroaki Toba and Hiromitsu Takizawa : 高齢乳癌患者におけるCDK4/6阻害剤投与の検討, 第31回日本乳癌学会学術総会, Jun. 2023.
53.	Shin-ichi Sakamoto, 井﨑富由実, Taihei Takeuchi, Hiroyuki Sumitomo, Naoki Miyamoto, Mika Takashima, Naoya Kawakita, Yukikiyo Kawakami, Hiroaki Toba, Kazuya Kondo and Hiromitsu Takizawa : 左下葉肺癌に対しExtended sleeve lobectomy type Cを行った一例, 第46回日本呼吸器内視鏡学会学術集会, Jun. 2023.
54.	Mika Takashima, Hiroaki Toba, 井﨑富由実, Taihei Takeuchi, Shin-ichi Sakamoto, Hiroyuki Sumitomo, Naoki Miyamoto, Naoya Kawakita, Yukikiyo Kawakami, Kazuya Kondo and Hiromitsu Takizawa : 進行肺癌の気道狭窄に対する気道ステント留置例の検討, 第46回日本呼吸器内視鏡学会学術集会, Jun. 2023.
55.	Hiroyuki Sumitomo, Hiroaki Toba, 井﨑富由実, Taihei Takeuchi, Shin-ichi Sakamoto, Naoki Miyamoto, Mika Takashima, Naoya Kawakita and Hiromitsu Takizawa : 保存的治療が奏功した，右下葉切除後気管支断端瘻の1例, 第46回日本呼吸器内視鏡学会学術集会, Jun. 2023.
56.	Hiroaki Toba, Naoya Kawakita, Hiroyuki Sumitomo, Shin-ichi Sakamoto, Mika Takashima, Yukikiyo Kawakami, Kazuya Kondo and Hiromitsu Takizawa : 小型末梢肺病変を正確に診断するためのCone-beam CTの意義, 第46回日本呼吸器内視鏡学会学術集会, Jun. 2023.
57.	Hiromitsu Takizawa, 細川暉雄, 井﨑富由実, Taihei Takeuchi, Shin-ichi Sakamoto, Hiroyuki Sumitomo, Naoki Miyamoto, Atsushi Morishita, Mika Takashima, Naoya Kawakita, Hiroaki Toba and Kazuya Kondo : Cone-beam CTガイド下金属コイルマーキングによる術中小型肺病変同定, 第46回日本呼吸器内視鏡学会学術集会, Jun. 2023.
58.	Naoya Kawakita, 井﨑富由実, Taihei Takeuchi, Hiroyuki Sumitomo, Naoki Miyamoto, Shin-ichi Sakamoto, Mika Takashima, Yukikiyo Kawakami, Kazuya Kondo, Hiroaki Toba and Hiromitsu Takizawa : Cone-beam CTガイド下極細径気管支鏡下生検におけるチャネル径の違いがもたらす意義, 第46回日本呼吸器内視鏡学会学術集会, Jun. 2023.
59.	Sawaka Yukishige, Hiroaki Inoue, Tomohiro Inui, Souichiro Sasa, Mariko Aoyama, Kazumasa Okumura, Hiroyuki Morino, 吉田友紀子, 宮本容子 and Hiromitsu Takizawa : BRCA遺伝学的検査の結果inconclusiveとなった3例, 第29回日本遺伝性腫瘍学会学術集会, Jun. 2023.
60.	Shin-ichi Sakamoto, Mariko Aoyama, 井﨑富由実, Taihei Takeuchi, Hiroyuki Sumitomo, Naoki Miyamoto, Seiya Inoue, Satoshi Fujiwara, Masakazu Goto, Hiroaki Toba and Hiromitsu Takizawa : レンバチニブ投与により難治性気胸を発症した甲状腺未分化癌の一例, 第35回日本内分泌外科学会総会, Jun. 2023.
61.	井﨑富由実, Mariko Aoyama, Taihei Takeuchi, Hiroyuki Sumitomo, Naoki Miyamoto, Shin-ichi Sakamoto, Satoshi Fujiwara, Seiya Inoue, Masakazu Goto, Hiroaki Toba and Hiromitsu Takizawa : 排便時の怒責が誘因となった甲状腺被膜出血の1例, 第35回日本内分泌外科学会総会, Jun. 2023.
62.	Mariko Aoyama, 井﨑富由実, Tomohiro Inui, Shin-ichi Sakamoto, Naoki Miyamoto, Seiya Inoue, Naoya Kawakita, Satoshi Fujiwara, Masakazu Goto, Hiroaki Toba and Hiromitsu Takizawa : VANS甲状腺悪性腫瘍手術の手術成績, 第35回日本内分泌外科学会総会, Jun. 2023.
63.	Naoki Miyamoto, 井﨑富由実, Taihei Takeuchi, Hiroyuki Sumitomo, Shin-ichi Sakamoto, Mika Takashima, Naoya Kawakita, Yukikiyo Kawakami, Kazuya Kondo, Hiroaki Toba and Hiromitsu Takizawa : モバイルCアーム3D画像と金属コイルマーキングによる術中小型肺病変同定, 第123回日本外科学会定期学術集会, Apr. 2023.
64.	Seiya Inoue, Masakazu Goto, Satoshi Fujiwara, 井﨑富由実, Taihei Takeuchi, Hiroyuki Sumitomo, Naoki Miyamoto, Shin-ichi Sakamoto, Mariko Aoyama, Mika Takashima, Naoya Kawakita, Hiroaki Toba, Hiromitsu Takizawa and Yoshihiro Tsuruo : 縦隔鏡下食道切除術における開胸手技習得のわれわれの取り組み, 第123回日本外科学会定期学術集会, Apr. 2023.
65.	Hiroaki Inoue, Souichiro Sasa, Tomohiro Inui, Mariko Aoyama, Kazumasa Okumura, Naoki Miyamoto, Hiroaki Toba, Yoshimi Bando and Hiromitsu Takizawa : 針生検における非浸潤癌周囲のTILsは浸潤癌の存在を予測できるか, 第123回日本外科学会定期学術集会, Apr. 2023.
66.	Naoya Kawakita, Hiroaki Toba, Shin-ichi Sakamoto, 井﨑富由実, Taihei Takeuchi, Hiroyuki Sumitomo, Naoki Miyamoto, Mariko Aoyama, Mika Takashima, Daisuke Matsumoto, Seiya Inoue, Yukikiyo Kawakami, Kazuya Kondo and Hiromitsu Takizawa : マウスiPS細胞由来の気管支肺胞幹細胞を用いた気道上皮再生, 第123回日本外科学会定期学術集会, Apr. 2023.
67.	Hiroyuki Sumitomo, Hiroaki Toba, 井﨑富由実, Taihei Takeuchi, Tomohiro Inui, Shin-ichi Sakamoto, Naoki Miyamoto, Souichiro Sasa, Mariko Aoyama, Hiroaki Inoue, Mika Takashima, Seiya Inoue, Naoya Kawakita, Satoshi Fujiwara, Masakazu Goto, Kazumasa Okumura, Yukikiyo Kawakami and Hiromitsu Takizawa : 大きな縦隔腫瘍に対する気縦隔を用いた縦隔鏡アプローチの有用性, 第123回日本外科学会定期学術集会, Apr. 2023.
68.	Naoki Miyamoto, Kazuya Kondo, 井﨑富由実, 竹内大平, 住友弘幸, Shin-ichi Sakamoto, Mariko Aoyama, Mika Takashima, Naoya Kawakita, Yukikiyo Kawakami, Hiroaki Toba and Hiromitsu Takizawa : A case of edema and weight gain as irAE after nivolumab administration, 第20回日本臨床腫瘍学会学術集会, Mar. 2023.
69.	井﨑富由実, Mariko Aoyama, 竹内大平, Hiroyuki Sumitomo, Naoki Miyamoto, Shin-ichi Sakamoto, Satoshi Fujiwara, Seiya Inoue, Masakazu Goto, Hiroaki Toba and Hiromitsu Takizawa : 抗血栓薬内服中に甲状腺被膜出血をきたし緊急手術を要した1例, 第51回中国四国甲状腺外科研究会, Feb. 2023.
70.	Shin-ichi Sakamoto, Mariko Aoyama, Tomohiro Inui, Naoki Miyamoto, Seiya Inoue, Satoshi Fujiwara, Masakazu Goto, Hiroaki Toba and Hiromitsu Takizawa : Weekly paclitaxelと放射線外照射を併用した甲状腺未分化癌の一例, 第51回中国四国甲状腺外科研究会, Feb. 2023.
71.	Mariko Aoyama, 井﨑富由実, 竹内大平, Shin-ichi Sakamoto, Naoki Miyamoto, Seiya Inoue, Naoya Kawakita, Satoshi Fujiwara, Masakazu Goto, Hiroaki Toba and Hiromitsu Takizawa : 分子標的治療薬の手術前使用の経験, 第51回中国四国甲状腺外科研究会, Feb. 2023.
72.	Hiroaki Toba, Shin-ichi Sakamoto, Hiroyuki Sumitomo, Naoki Miyamoto, Mika Takashima, Naoya Kawakita, Yukikiyo Kawakami, Kazuya Kondo and Hiromitsu Takizawa : 進行再発胸腺癌に対するレンバチニブの使用経験, 第42回日本胸腺研究会, Feb. 2023.
73.	Ryota Mitsuhashi, Takayoshi Shinya, Hideaki Enomoto, Youichi Otomi, Hideki Otsuka, Masafumi Harada, Seiji Iwamoto, Takashi Kawanaka, Hiroaki Toba, Hiromitsu Takizawa, Yoshimi Bando and Hisanori Uehara : 前縦隔に発生したmyxofibrosarcomaの一例, 第137回日本医学放射線学会中国・四国地方会, Dec. 2022.
74.	Rinen Choh, Kazuya Kondo, Takae Bando, Aki Takahashi, Yoshie Imai, Mika Takashima, Shin-ichi Sakamoto, Naoki Miyamoto, Naoya Kawakita, Yukikiyo Kawakami, Mitsuteru Yoshida, Hiroaki Toba and Hiromitsu Takizawa : 高齢者肺癌患者における高齢者機能評価を用いた外科治療の適応の検討, 第63回日本肺癌学会学術集会, Dec. 2022.
75.	Munkhjargal Batkhishig, Kazuya Kondo, 副島志帆, Tegshee Bilguun, Mitsuhiro Tsuboi, Koichiro Kajiura, Yukikiyo Kawakami, Naoya Kawakita, Hiroaki Toba, Mitsuteru Yoshida and Hiromitsu Takizawa : ZNF577 functions as a tumor suppressor gene in lung adenocarcinoma, 第63回日本肺癌学会学術集会, Dec. 2022.
76.	Kazuya Kondo, 副島志帆, Batkhishig Munkhjargal, Yukikiyo Kawakami, Naoya Kawakita, Hiroaki Toba and Hiromitsu Takizawa : 胸腺上皮性腫瘍におけるepigeneticな異常, 第63回日本肺癌学会学術集会, Dec. 2022.
77.	竹内大平, Masakazu Goto, 井﨑富由実, 住友弘幸, Seiya Inoue, Satoshi Fujiwara and Hiromitsu Takizawa : 遠隔期再発を来した食道癌の1例より術後サーベイランスについて考える, 第84回日本臨床外科学会総会, Nov. 2022.
78.	Shin-ichi Sakamoto, Naoya Kawakita, Naoki Miyamoto, Mika Takashima, Yukikiyo Kawakami, Hiroaki Toba, Kazuya Kondo and Hiromitsu Takizawa : 臨床病期Ⅰ期の間質性肺疾患合併肺癌の検討, 第84回日本臨床外科学会総会, Nov. 2022.
79.	Hiroaki Toba, Shin-ichi Sakamoto, Naoki Miyamoto, Mika Takashima, Naoya Kawakita, Yukikiyo Kawakami, Kazuya Kondo and Hiromitsu Takizawa : 小型末梢肺病変に対する単孔式胸腔鏡下肺部分切除∼全身麻酔下にHybrid手術室で，コイルと色素を併用した気管支鏡下マーキング法を用いて, 第84回日本臨床外科学会総会, Nov. 2022.
80.	Masakazu Goto, 井﨑富由実, 竹内大平, Hiroyuki Sumitomo, Satoshi Fujiwara, Seiya Inoue and Hiromitsu Takizawa : 術前化学療法によりpCRが得られた食道癌24例の検討とその後の転帰について, 第33回日本消化器癌発生学会総会, Nov. 2022.
81.	Souichiro Sasa, Hiroaki Inoue, INUI Tomohiro, Naoki Miyamoto, Mariko Aoyama, Kazumasa Okumura, Masakazu Goto, Hiroaki Toba and Hiromitsu Takizawa : 原因不明の発熱により治療方針決定に難渋した局所進行乳癌の一例, 第32回日本乳癌検診学会学術総会, Nov. 2022.
82.	Hiroaki Inoue, Souichiro Sasa, Tomohiro Inui, Mariko Aoyama, Kazumasa Okumura, Hiroyuki Sumitomo, Naoki Miyamoto, Hiroaki Toba, Yuka Hiroshima and Hiromitsu Takizawa : 当院におけるトモシンセシスガイド下マンモトーム生検の経験, 第32回日本乳癌検診学会学術総会, Nov. 2022.
83.	Souichiro Sasa, Hiroaki Inoue, Tomohiro Inui, Mariko Aoyama, Kazumasa Okumura, 板東真由, Ichiro Hashimoto, Atsuko Yoshida, 山口美代子, Hiroaki Toba, Masakazu Goto and Hiromitsu Takizawa : 多診療科・多職種チーム連携が有用であった妊娠期乳癌の1例, 第10回日本乳房オンコプラスティックサージャリー学会総会, Oct. 2022.
84.	Hiroaki Toba, Hiroaki Inoue, Mika Takashima, Seiya Inoue, Naoya Kawakita, Masakazu Goto and Hiromitsu Takizawa : より良いがんの地域連携体制構築のための包括的な取り組み, 第60回日本癌治療学会学術集会, Oct. 2022.
85.	Hiroaki Toba, Shin-ichi Sakamoto, Naoki Miyamoto, Mika Takashima, Naoya Kawakita, Yukikiyo Kawakami, Kazuya Kondo and Hiromitsu Takizawa : 小型末梢肺病変に対する気管支鏡下コイルマーキングを用いたimage-guided VATS, 第75回日本胸部外科学会定期学術集会, Oct. 2022.
86.	Naoya Kawakita, Hiroaki Toba, Shin-ichi Sakamoto, 竹内大平, 住友弘幸, Naoki Miyamoto, Mika Takashima, Daisuke Matsumoto, Seiya Inoue, Takeshi Nishino and Hiromitsu Takizawa : マウスiPS細胞由来の気管支肺胞幹細胞は気道上皮再生を促進する, 第75回日本胸部外科学会定期学術集会, Oct. 2022.
87.	Seiya Inoue, Masakazu Goto, Satoshi Fujiwara, Takahiro Yoshida, Akira Tangoku, 竹内大平, 住友弘幸, Naoki Miyamoto, Shin-ichi Sakamoto, Mika Takashima, Naoya Kawakita, Hiroaki Toba, Hiromitsu Takizawa and 鶴尾吉保 : 縦隔鏡下食道切除術を安全に行うためのわれわれのトレーニング, 第75回日本胸部外科学会定期学術集会, Oct. 2022.
88.	Masakazu Goto, Satoshi Fujiwara, Seiya Inoue, Takahiro Yoshida and Hiromitsu Takizawa : 腹臥位食道亜全摘術導入後の胸部操作時間のラーニングカーブについて, 第76回日本食道学会学術集会, Sep. 2022.
89.	Satoshi Fujiwara, Takahiro Yoshida, Masakazu Goto, Seiya Inoue, INUI Tomohiro, Shin-ichi Sakamoto, Naoki Miyamoto, Mariko Aoyama, Hiroaki Toba and Hiromitsu Takizawa : 同時性肺腫瘍を伴う進行食道癌に対し，一期的手術を施行した3例の検討, 第76回日本食道学会学術集会, Sep. 2022.
90.	Seiya Inoue, Takahiro Yoshida, Masakazu Goto, Satoshi Fujiwara, INUI Tomohiro, Shin-ichi Sakamoto, Naoki Miyamoto, Mariko Aoyama, Hiroaki Toba and Hiromitsu Takizawa : 食道切除後の最適な胃管再建法, 第76回日本食道学会学術集会, Sep. 2022.
91.	Seiya Inoue, Masakazu Goto, Satoshi Fujiwara, Hiroyuki Sumitomo, 井﨑富由実, 竹内大平, Tomohiro Inui, Shin-ichi Sakamoto, Naoki Miyamoto, Mariko Aoyama, Hiroaki Toba and Hiromitsu Takizawa : 食道胃管吻合におけるわれわれの取り組み, 第97回中国四国外科学会総会/第27回中国四国内視鏡外科研究会, Sep. 2022.
92.	Hiroaki Inoue, INUI Tomohiro, Souichiro Sasa, Mariko Aoyama, Kazumasa Okumura, Naoki Miyamoto, Masakazu Goto, Hiroaki Toba and Hiromitsu Takizawa : 骨髄癌症，硬膜下血腫によりoncological emergencyの状態であったが救命し得た乳癌多発骨転移の1例, 第97回中国四国外科学会総会/第27回中国四国内視鏡外科研究会, Sep. 2022.
93.	Mariko Aoyama, Shin-ichi Sakamoto, INUI Tomohiro, Naoki Miyamoto, Seiya Inoue, Satoshi Fujiwara, Masakazu Goto, Hiroaki Toba and Hiromitsu Takizawa : Weekly pacltaxelと放射線外照射が有効であった甲状腺未分化癌の1例, 第97回中国四国外科学会総会/第27回中国四国内視鏡外科研究会, Sep. 2022.
94.	Naoki Miyamoto, Kazuya Kondo, 井﨑富由実, 竹内大平, Shin-ichi Sakamoto, Mika Takashima, Naoya Kawakita, Yukikiyo Kawakami, Hiroaki Toba and Hiromitsu Takizawa : 当院で経験したmicronodular thymic tumorの検討, 第97回中国四国外科学会総会/第27回中国四国内視鏡外科研究会, Sep. 2022.
95.	Seiya Inoue, Takahiro Yoshida, Masakazu Goto, Satoshi Fujiwara, INUI Tomohiro, Shin-ichi Sakamoto, Naoki Miyamoto, Mariko Aoyama, Hiroaki Toba and Hiromitsu Takizawa : 食道切除後再建術における取り組み-ICG血流評価法とCollard変法の有用性-, 第77回日本消化器外科学会総会, Jul. 2022.
96.	Shun-ichi Toki, Toshihiko Nishisho, 上原久典, Yoshimi Bando, 尾矢剛志, Shoichiro Takao, 外礒千智, 新井悠太, 西村正人, 高橋正幸, Kei Daizumoto, 渡辺浩良, Ryo Miyagi, Hiromitsu Takizawa, 吉川幸造, 徳永卓哉, 安倍吉郎, 中村信元, 宮本弘志 and Koichi Sairyo : 肉腫診療における多施設多診療科多職種カンファレンスの意義, 第35回日本臨床整形外科学会学術集会【開催期間:2022年7月17日-18日】, Jul. 2022.
97.	Mariko Aoyama, Hiroaki Inoue, INUI Tomohiro, Souichiro Sasa, Kazumasa Okumura, Hiroaki Toba, Takahiro Yoshida and Hiromitsu Takizawa : 3次治療でオラパリブが著効したBRCA陽性転移再発乳癌の1例, 第30回日本乳癌学会学術総会(ハイブリッド開催), Jun. 2022.
98.	Kazumasa Okumura, INUI Tomohiro, Souichiro Sasa, Mariko Aoyama, Hiroaki Inoue, Hiroaki Toba, Takahiro Yoshida, Hiromitsu Takizawa and Akira Tangoku : ペムブロリズムマブの免疫関連副作用と考えられた甲状腺中毒，DICを発症しステロイドが著効した1例, 第30回日本乳癌学会学術総会(ハイブリッド開催), Jun. 2022.
99.	INUI Tomohiro, Hiroaki Inoue, Souichiro Sasa, Mariko Aoyama, Kazumasa Okumura, Naoki Miyamoto, Hiroaki Toba, Hiromitsu Takizawa and Akira Tangoku : 薬剤性肝障害を来したがCDK4/6阻害薬を変更し治療継続し得た2例, 第30回日本乳癌学会学術総会(ハイブリッド開催), Jun. 2022.
100.	Souichiro Sasa, Hiroaki Inoue, INUI Tomohiro, Naoki Miyamoto, Mariko Aoyama, Kazumasa Okumura, Takahiro Yoshida, Hiroaki Toba and Hiromitsu Takizawa : 当院におけるコンパニオン診断目的に行われたBRCA1/2遺伝学的検査の現状とオラパリブの使用経験, 第30回日本乳癌学会学術総会(ハイブリッド開催), Jun. 2022.
101.	Hiroaki Inoue, 山下華乃, Souichiro Sasa, INUI Tomohiro, Mariko Aoyama, Kazumasa Okumura, Naoki Miyamoto, Hiroaki Toba, Takahiro Yoshida, Yoshimi Bando, Hiromitsu Takizawa and Akira Tangoku : 非浸潤癌におけるTILsは浸潤の有無を予測できるか, 第30回日本乳癌学会学術総会(ハイブリッド開催), Jun. 2022.
102.	Mariko Aoyama, INUI Tomohiro, Shin-ichi Sakamoto, Naoki Miyamoto, Seiya Inoue, Naoya Kawakita, Satoshi Fujiwara, Masakazu Goto, Hiroaki Toba and Hiromitsu Takizawa : 肺転移と腎転移をきたした甲状腺乳頭癌の1症例, 第34回日本内分泌外科学会総会(ハイブリッド開催), Jun. 2022.
103.	Shin-ichi Sakamoto, Naoya Kawakita, Hiroaki Toba, Naoki Miyamoto, Mika Takashima, Yukikiyo Kawakami, Kazuya Kondo and Hiromitsu Takizawa : Endobronchial Watanabe Spigotを用いて喀血を制御し得た3例, 第45回日本呼吸器内視鏡学会学術集会, May 2022.
104.	Mika Takashima, Hiroaki Toba, Shin-ichi Sakamoto, Naoki Miyamoto, Naoya Kawakita, Yukikiyo Kawakami, Kazuya Kondo and Hiromitsu Takizawa : 悪性気道狭窄に対する気道ステント留置例の検討, 第45回日本呼吸器内視鏡学会学術集会, May 2022.
105.	Hiroaki Toba, Takeshi Nishino, Naoya Kawakita, Shin-ichi Sakamoto, Naoki Miyamoto, Mika Takashima, Yukikiyo Kawakami, Kazuya Kondo and Hiromitsu Takizawa : コンベックスEBUSは局所進行食道癌の気管・気管支浸潤の診断に有用である, 第45回日本呼吸器内視鏡学会学術集会, May 2022.
106.	Naoya Kawakita, Hiromitsu Takizawa, Naoki Miyamoto, Shin-ichi Sakamoto, Mika Takashima, Hiroaki Toba, Yukikiyo Kawakami, Mitsuteru Yoshida and Kazuya Kondo : 末梢肺病変に対するCone-beam CT併用EBUS-UT法の導入, 第45回日本呼吸器内視鏡学会学術集会, May 2022.
107.	Hiromitsu Takizawa : 《教育講演》Cone-beam CTガイド下気管支鏡, 第45回日本呼吸器内視鏡学会学術集会, May 2022.
108.	Mika Takashima, Hiroaki Toba, Shin-ichi Sakamoto, Naoki Miyamoto, Naoya Kawakita, Yukikiyo Kawakami, Mitsuteru Yoshida, Kazuya Kondo and Hiromitsu Takizawa : 気管支断端補強，肺瘻修復に遊離心膜脂肪織を使用した症例の臨床的検討, 第39回日本呼吸器外科学会学術集会(ハイブリッド開催), May 2022.
109.	Hiroaki Toba, Koichiro Kenzaki, Shin-ichi Sakamoto, Naoki Miyamoto, Mika Takashima, Naoya Kawakita, Yukikiyo Kawakami, Kazuya Kondo and Hiromitsu Takizawa : 未確診肺病変に対するRATS∼特にステイプラ使用本数に着目して, 第39回日本呼吸器外科学会学術集会(ハイブリッド開催), May 2022.
110.	Hiromitsu Takizawa, Shin-ichi Sakamoto, Naoki Miyamoto, Mika Takashima, Naoya Kawakita, Yukikiyo Kawakami, Mitsuteru Yoshida, Hiroaki Toba and Kazuya Kondo : 肺癌手術における気管支動脈先行処理, 第39回日本呼吸器外科学会学術集会(ハイブリッド開催), May 2022.
111.	Naoki Miyamoto, Shin-ichi Sakamoto, Mika Takashima, Naoya Kawakita, Yukikiyo Kawakami, Hiroaki Toba, Kazuya Kondo and Hiromitsu Takizawa : コロナワクチン接種後に手術を行い，術後感染性合併症を契機にIgA血管炎を併発した2例, 第39回日本呼吸器外科学会学術集会(ハイブリッド開催), May 2022.
112.	Naoya Kawakita, Hiroaki Toba, Naoki Miyamoto, Shin-ichi Sakamoto, Mika Takashima, Yukikiyo Kawakami, Kazuya Kondo and Hiromitsu Takizawa : pStageⅠ肺腺癌の最適な個別化治療に向けて, 第39回日本呼吸器外科学会学術集会(ハイブリッド開催), May 2022.
113.	Mitsuteru Yoshida, 大石久, Mckee D Trevor, Guana Zehong, Liu Mingyao, Naoki Miyamoto, Shin-ichi Sakamoto, Mika Takashima, Naoya Kawakita, Hiroaki Toba, Yukikiyo Kawakami, Hiromitsu Takizawa and Kazuya Kondo : マウス肺移植後の慢性拒絶反応におけるAI評価の経験, 第39回日本呼吸器外科学会学術集会(ハイブリッド開催), May 2022.
114.	Shin-ichi Sakamoto, Naoya Kawakita, Hiroaki Toba, Naoki Miyamoto, Mika Takashima, Yukikiyo Kawakami, Kazuya Kondo and Hiromitsu Takizawa : ILD-GAP indexを用いた間質性肺炎合併肺癌の治療戦略-予後因子に基づく層別化治療-, 第39回日本呼吸器外科学会学術集会(ハイブリッド開催), May 2022.
115.	Seiya Inoue, Takahiro Yoshida, Masakazu Goto, Satoshi Fujiwara, Mariko Aoyama, Naoya Kawakita, Hiroaki Toba, Hiromitsu Takizawa, 橋本脩平 and Yasuhiro Hamada : 食道癌根治術における術前GLIM criteriaを用いた術後成績の予測, 第122回日本外科学会定期学術集会(ハイブリッド開催), Apr. 2022.
116.	Mitsuteru Yoshida, Kazuya Kondo, Takashi Kitaichi, Toshihiko Nishisho, 出水祐介, Takeshi Oya, Naoki Miyamoto, Yukikiyo Kawakami, Shin-ichi Sakamoto, Mika Takashima, Naoya Kawakita, Hiroaki Toba and Hiromitsu Takizawa : 浸潤性縦隔腫瘍にいかに立ち向かうか-希少腫瘍の治療への挑戦-, 第122回日本外科学会定期学術集会(ハイブリッド開催), Apr. 2022.
117.	Hiroaki Inoue, Souichiro Sasa, INUI Tomohiro, Mariko Aoyama, Kazumasa Okumura, Naoki Miyamoto, Hiroaki Toba, Takahiro Yoshida and Hiromitsu Takizawa : エリブリン投与中の末梢血総リンパ球数変化率は進行・再発乳癌の予後予測因子となるか, 第122回日本外科学会定期学術集会(ハイブリッド開催), Apr. 2022.
118.	Hiroaki Toba, Takeshi Nishino, 坂本晋一, 宮本直輝, Mika Takashima, Naoya Kawakita, Yukikiyo Kawakami, Mitsuteru Yoshida, Kazuya Kondo and Hiromitsu Takizawa : コンベックスEBUSが治療前後の気管膜様部浸潤の診断に有用であった局所進行食道癌の1切除例, 第30回日本呼吸器内視鏡学会中国四国支部会, Dec. 2021.
119.	Mika Takashima, Hiroaki Toba, Souji Kakiuchi, Shinichi Sakamoto, Naoki Miyamoto, Naoya Kawakita, Yukikiyo Kawakami, Mitsuteru Yoshida, Kazuya Kondo and Hiromitsu Takizawa : 気管瘻を伴った進行肺癌による気道狭窄に対し気道ステント留置により長期にわたり良好なQOLを維持できた1例, 第30回日本呼吸器内視鏡学会中国四国支部会, Dec. 2021.
120.	Naoya Kawakita, Hiromitsu Takizawa, 宮本直輝, 坂本晋一, Mika Takashima, Mitsuteru Yoshida, Yukikiyo Kawakami and Kazuya Kondo : 長期金属ステント留置に伴う狭窄に対し，複数回のインターベンションを要した1例, 第30回日本呼吸器内視鏡学会中国四国支部会, Dec. 2021.
121.	副島志帆, Kazuya Kondo, Mitsuhiro Tsuboi, Birgun Tegsee, 六車京香, Naoya Kawakita, Hiroaki Toba, Mitsuteru Yoshida, Hiromitsu Takizawa and Akira Tangoku : 肺腺癌におけるPEAR1発現の臨床的意義, 第62回日本肺癌学会学術集会, Nov. 2021.
122.	Rinen Choh, Kazuya Kondo, Takae Bando, Yoshie Imai, Aki Takahashi, 荒堀広美, YAO RENYIN, 孫楽キ, Hiromitsu Takizawa, Yukikiyo Kawakami, Mitsuteru Yoshida, Hiroaki Toba, Mitsuhiro Tsuboi and Akira Tangoku : 肺癌患者の周術期における息苦しさの評価, 第62回日本肺癌学会学術集会, Nov. 2021.
123.	Mitsuteru Yoshida, Kazuya Kondo, 湯浅将生, 宮本直輝, Yukikiyo Kawakami, 坂本晋一, Mika Takashima, Naoya Kawakita, Hiroaki Toba and Hiromitsu Takizawa : CT画像から胸腺腫の手術を議論できるか(石灰化と残存脂肪組織の三次元解析), 第62回日本肺癌学会学術集会, Nov. 2021.
124.	Hiroaki Inoue, Soichiroh Sasa, Tomohiro INUI, Mariko Aoyama, Kazumasa Okumura, Hiroaki Toba, Takahiro Yoshida, Hiromitsu Takizawa and Akira Tangoku : 当院におけるAYA世代乳癌患者の発見契機と予後について, 第31回日本乳癌検診学会学術総会(ハイブリッド開催), Nov. 2021.
125.	Mitsuteru Yoshida, Naoki Miyamoto, Yukikiyo Kawakami, Kazuya Kondo, Shinichi SAKAMOTO, Mika Takashima, Naoya Kawakita, Hiroaki Toba and Hiromitsu Takizawa : 難治性肺瘻に対する適切な治療戦略は決定できるか, 第74回日本胸部外科学会定期学術集会, Oct. 2021.
126.	Satoshi Fujiwara, Takahiro Yoshida, Takeshi Nishino, Hiroaki Toba, Seiya Inoue, Masakazu Goto, Naoya Kawakita and Hiromitsu Takizawa : 超音波気管支鏡による進行食道癌の壁深達度診断と治療戦略, 第74回日本胸部外科学会定期学術集会, Oct. 2021.
127.	Mariko Aoyama, Tomohiro INUI, 坂本晋一, 宮本直輝, Seiya Inoue and Hiromitsu Takizawa : EMG気管チューブの声帯圧迫によって両側声帯神経麻痺を来したと考えられる2例, 第54回日本内分泌外科学会学術大会(WEB開催), Oct. 2021.
128.	Hidenori Maki, Seiya Inoue, 南城和正, Mariko Aoyama, Masakazu Goto, Takeshi Nishino, Takahiro Yoshida, Hiromitsu Takizawa and Akira Tangoku : 巨大食道裂孔ヘルニアを伴う特発性食道破裂の一例, 第75回日本食道学会学術集会(ハイブリッド開催), Sep. 2021.
129.	南城和正, Seiya Inoue, Hidenori Maki, 庄野隆志, Mariko Aoyama, Takeshi Nishino, Masakazu Goto, Takahiro Yoshida, Hiromitsu Takizawa and Akira Tangoku : 食道癌術後に門脈ガス血症・腸管気腫症を発症した1例, 第75回日本食道学会学術集会(ハイブリッド開催), Sep. 2021.
130.	庄野隆志, Seiya Inoue, 南城和正, Yasuyo Saijo, Hidenori Maki, Mariko Aoyama, Takeshi Nishino, Masakazu Goto, Takahiro Yoshida, Hiromitsu Takizawa and Akira Tangoku : 術前化学療法に効果を示し，根治手術を施行した進行食道粘表皮癌の1例, 第75回日本食道学会学術集会(ハイブリッド開催), Sep. 2021.
131.	乾友浩, Hiroaki Inoue, Soichiroh Sasa, Mariko Aoyama, Kazumasa Okumura, 宮本直輝, Hiroaki Toba, Takahiro Yoshida and Hiromitsu Takizawa : アベマシクリブ投与中に重篤な間質性肺炎を来したが救命しえた1例, 第18回日本乳癌学会中国四国地方会(WEB開催), Sep. 2021.
132.	Naoki Miyamoto, Shinichi SAKAMOTO, Mika Takashima, Naoya Kawakita, Hiroaki Toba, Yukikiyo Kawakami, Mitsuteru Yoshida, Kazuya Kondo and Hiromitsu Takizawa : 血中CA19-9が異常高値を示した成熟縦隔奇形種の1切除例, 第96回中国四国外科学会総会・第26回中国四国内視鏡外科研究会, Sep. 2021.
133.	Takahiro Yoshida, Masakazu Goto, Seiya Inoue, Satoshi Fujiwara, Hiromitsu Takizawa, Akira Tangoku and Takeshi Nishino : 反回神経麻痺回避のための左頸部アポローチによる縦隔鏡下左反回神経周囲リンパ節郭清の工夫, 第96回中国四国外科学会総会・第26回中国四国内視鏡外科研究会, Sep. 2021.
134.	Shinichi Sakamoto, Hiromitsu Takizawa, Naoki Miyamoto, Mika Takashima, Naoya Kawakita, Hiroaki Toba, Yukikiyo Kawakami, Mitsuteru Yoshida and Kazuya Kondo : FDG-PET/CT画像を元に金属コイルマーキングを行い診断した間質性肺炎合併肺癌の一例, 第59回日本肺癌学会中国・四国支部学術集会, Aug. 2021.
135.	Shinichi Sakamoto, Hiromitsu Takizawa, 山本清成, Naoki Miyamoto, Mika Takashima, Daisuke Matsumoto, Naoya Kawakita, Hiroaki Toba, Yukikiyo Kawakami, Mitsuteru Yoshida, Kazuya Kondo and Akira Tangoku : 左B1+2転位気管支とV1+2の走行異常を認める左下葉肺癌の一切除例, 第44回日本呼吸器内視鏡学会学術集会(ハイブリッド開催), Jun. 2021.
136.	Daisuke Matsumoto, Hiroaki Toba, 庄野隆志, 南城和正, 山本清成, Naoki Miyamoto, Shinichi Sakamoto, Mika Takashima, Naoya Kawakita, Yukikiyo Kawakami, Mitsuteru Yoshida, Hiromitsu Takizawa, Kazuya Kondo and Akira Tangoku : コイルと色素を併用した気管支鏡下マーキング法による，触知困難小型病変に対する単孔式胸腔鏡下肺部分切除, 第44回日本呼吸器内視鏡学会学術集会(ハイブリッド開催), Jun. 2021.
137.	Mika Takashima, Hiroaki Toba, 山本清成, Shinichi Sakamoto, Naoki Miyamoto, Daisuke Matsumoto, Naoya Kawakita, Yukikiyo Kawakami, Mitsuteru Yoshida, Hiromitsu Takizawa, Kazuya Kondo and Akira Tangoku : 進行食道癌による気道のEmergencyに対する気道ステント留置例の検討, 第44回日本呼吸器内視鏡学会学術集会(ハイブリッド開催), Jun. 2021.
138.	Hiromitsu Takizawa, Naoya Kawakita, 庄野隆志, 南城和正, 山本清成, Shinichi Sakamoto, Naoki Miyamoto, Mika Takashima, Daisuke Matsumoto, Hiroaki Toba, Yukikiyo Kawakami, Mitsuteru Yoshida, Kazuya Kondo and Akira Tangoku : 当科におけるCone-beam CT vs EBUS-GSガイド下経気管支生検による原発性肺癌診断の成績比較, 第44回日本呼吸器内視鏡学会学術集会(ハイブリッド開催), Jun. 2021.
139.	Naoya Kawakita, Hiromitsu Takizawa, Hiroaki Toba, 庄野隆志, 南城和正, 山本清成, Naoki Miyamoto, Shinichi Sakamoto, Mitsuteru Yoshida, Yukikiyo Kawakami, Kazuya Kondo and Akira Tangoku : 原発性肺癌診断におけるCone-beam CT vs CTガイド下気管支鏡下生検, 第44回日本呼吸器内視鏡学会学術集会(ハイブリッド開催), Jun. 2021.
140.	庄野隆志, Mariko Aoyama, 南城和正, 山本清成, Hidenori Maki, Tomohiro Inui, Shinichi Sakamoto, Tomoko Kobayashi, Shingen Nakamura, Hiromitsu Takizawa and Akira Tangoku : アブスコパル効果を示した甲状腺原発形質細胞腫の1例, 第33回日本内分泌外科学会総会, Jun. 2021.
141.	山本清成, Mariko Aoyama, Hiromitsu Takizawa, 南城和正, 庄野隆志, Hidenori Maki, Tomohiro Inui, Shinichi Sakamoto and Akira Tangoku : 右心房転移をきたした甲状腺未分化癌の1例, 第33回日本内分泌外科学会総会, Jun. 2021.
142.	Shinichi Sakamoto, Mariko Aoyama, Hiromitsu Takizawa, 庄野隆志, 山本清成 and Akira Tangoku : 低用量レンバチニブ投与で病勢コントロールを得た甲状腺乳頭癌の3例, 第33回日本内分泌外科学会総会, Jun. 2021.
143.	Mariko Aoyama, Hiromitsu Takizawa, 庄野隆志, 山本清成, Tomohiro Inui, Shinichi Sakamoto and Akira Tangoku : 原発性副甲状腺機能亢進症術後のテタニー発症の術前因子についての検討, 第33回日本内分泌外科学会総会, Jun. 2021.
144.	Hiromitsu Takizawa, Mariko Aoyama, 庄野隆志, 南城和正, 山本清成, Tomohiro Inui, Shinichi Sakamoto and Akira Tangoku : レンバチニブが甲状腺乳頭癌多発肺転移と腎細胞癌に有効であった1例, 第33回日本内分泌外科学会総会, Jun. 2021.
145.	山本清成, Naoya Kawakita, Hiroaki Toba, 南城和正, Naoki Miyamoto, Shinichi Sakamoto, Mika Takashima, Daisuke Matsumoto, Mitsuteru Yoshida, Yukikiyo Kawakami, Hiromitsu Takizawa, Kazuya Kondo and Akira Tangoku : pStageⅠ肺腺癌におけるVolume doubling timeとSUVmax，優位組織亜型の関係, 第38回日本呼吸器外科学会学術集会(Web開催), May 2021.
146.	南城和正, Naoya Kawakita, Mitsuteru Yoshida, 庄野隆志, 山本清成, Hidenori Maki, Shinichi Sakamoto, Naoki Miyamoto, Mika Takashima, Daisuke Matsumoto, Hiroaki Toba, Yukikiyo Kawakami, Hiromitsu Takizawa, Kazuya Kondo and Akira Tangoku : 肺アミロイドーシスを伴った上皮内肺腺癌の1例, 第38回日本呼吸器外科学会学術集会(Web開催), May 2021.
147.	Hiroaki Toba, Naoya Kawakita, Mika Takashima, 山本清成, Shinichi Sakamoto, Naoki Miyamoto, Daisuke Matsumoto, Yukikiyo Kawakami, Mitsuteru Yoshida, Hiromitsu Takizawa, Kazuya Kondo and Akira Tangoku : 右B2転位気管支・V2破格・上下葉間分葉不全を伴う右下葉肺癌症例に対するRATS, 第38回日本呼吸器外科学会学術集会(Web開催), May 2021.
148.	庄野隆志, Hiromitsu Takizawa, 南城和正, 山本清成, Naoki Miyamoto, Shinichi Sakamoto, Mika Takashima, Daisuke Matsumoto, Naoya Kawakita, Mitsuteru Yoshida, Hiroaki Toba, Yukikiyo Kawakami, Kazuya Kondo and Akira Tangoku : 網膜芽細胞腫治療後に後縦隔に発生した平滑筋肉腫の一例, 第38回日本呼吸器外科学会学術集会(Web開催), May 2021.
149.	Hiromitsu Takizawa, 庄野隆志, 南城和正, 山本清成, Hidenori Maki, Shinichi Sakamoto, Naoki Miyamoto, Mika Takashima, Daisuke Matsumoto, Naoya Kawakita, Hiroaki Toba, Yukikiyo Kawakami, Mitsuteru Yoshida, Kazuya Kondo and Akira Tangoku : 肺癌手術におけるICG蛍光を用いた気管支動脈可視化の意義, 第38回日本呼吸器外科学会学術集会(Web開催), May 2021.
150.	Naoki Miyamoto, Kazuya Kondo, 南城和正, 庄野隆志, 山本清成, Hidenori Maki, Shinichi Sakamoto, Mika Takashima, Daisuke Matsumoto, Naoya Kawakita, Hiroaki Toba, Yukikiyo Kawakami, Mitsuteru Yoshida, Hiromitsu Takizawa and Akira Tangoku : 当院で経験したmicronodular thymic tumorの3例, 第38回日本呼吸器外科学会学術集会(Web開催), May 2021.
151.	Mika Takashima, Hiroaki Toba, 山本清成, Shinichi Sakamoto, Naoki Miyamoto, Daisuke Matsumoto, Naoya Kawakita, Yukikiyo Kawakami, Mitsuteru Yoshida, Hiromitsu Takizawa, Kazuya Kondo and Akira Tangoku : 悪性気道狭窄に対する気道ステント留置例の検討, 第38回日本呼吸器外科学会学術集会(Web開催), May 2021.
152.	Naoya Kawakita, Hiroaki Toba, 庄野隆志, 南城和正, 山本清成, Naoki Miyamoto, Shinichi Sakamoto, Mika Takashima, Mitsuteru Yoshida, Yukikiyo Kawakami, Hiromitsu Takizawa, Kazuya Kondo and Akira Tangoku : 浸潤径・SUVmaxで簡便にpStageⅠ肺腺癌の予後を層別化できる, 第38回日本呼吸器外科学会学術集会(Web開催), May 2021.
153.	Shinichi Sakamoto, Naoya Kawakita, Hiroaki Toba, 山本清成, Naoki Miyamoto, Mika Takashima, Daisuke Matsumoto, Yukikiyo Kawakami, Mitsuteru Yoshida, Hiromitsu Takizawa, Kazuya Kondo and Akira Tangoku : 間質性肺炎合併肺癌に対する予後予測因子の検討, 第38回日本呼吸器外科学会学術集会(Web開催), May 2021.
154.	Daisuke Matsumoto, Hiroaki Toba, Shinichi Sakamoto, Mika Takashima, Naoya Kawakita, 庄野隆志, 南城和正, Hidenori Maki, 山本清成, Naoki Miyamoto, Yukikiyo Kawakami, Mitsuteru Yoshida, Hiromitsu Takizawa, Kazuya Kondo and Akira Tangoku : ラット胎仔肺移植による肺再生へのアプローチ, 第38回日本呼吸器外科学会学術集会(Web開催), May 2021.
155.	Mitsuteru Yoshida, Kazuya Kondo, 湯浅将生, Naoki Miyamoto, Yukikiyo Kawakami, 山本清成, 南城和正, Shinichi Sakamoto, Mika Takashima, Daisuke Matsumoto, Naoya Kawakita, Hiroaki Toba, Hiromitsu Takizawa and Akira Tangoku : CT画像から胸腺の手術を考える, 第38回日本呼吸器外科学会学術集会(Web開催), May 2021.
156.	Mitsuteru Yoshida, 大石久, Naoki Miyamoto, Kazuya Kondo, Yukikiyo Kawakami, 南城和正, 山本清成, Shinichi Sakamoto, Mika Takashima, Daisuke Matsumoto, Naoya Kawakita, Hiroaki Toba, Hiromitsu Takizawa and Akira Tangoku : トランスレーショナルリサーチに必ず必要な外科技術-呼吸器外科から創薬への社会貢献を-, 第38回日本呼吸器外科学会学術集会(Web開催), May 2021.
157.	Daisuke Matsumoto, Naoya Kawakita, Hiromitsu Takizawa, 庄野隆志, 南城和正, Hidenori Maki, 山本清成, Shinichi Sakamoto, Naoki Miyamoto, Mika Takashima, Hiroaki Toba, Yukikiyo Kawakami, Mitsuteru Yoshida, Kazuya Kondo and Akira Tangoku : 肺切除術後に気管支鏡処置が必要な無気肺を発症するハイリスク患者群の抽出, 第121回日本外科学会定期学術集会, Apr. 2021.
158.	Hiromitsu Takizawa, 庄野隆志, 南城和正, Hidenori Maki, 山本清成, Shinichi Sakamoto, Naoki Miyamoto, Mika Takashima, Daisuke Matsumoto, Naoya Kawakita, Hiroaki Toba, Yukikiyo Kawakami, Mitsuteru Yoshida, Kazuya Kondo and Akira Tangoku : 発達した気管支動脈は術中出血と手術時間延長のリスク因子である, 第121回日本外科学会定期学術集会, Apr. 2021.
159.	Naoki Miyamoto, Kazuya Kondo, 南城和正, 庄野隆志, 山本清成, Hidenori Maki, Shinichi Sakamoto, Mika Takashima, Daisuke Matsumoto, Naoya Kawakita, Hiroaki Toba, Yukikiyo Kawakami, Mitsuteru Yoshida, Hiromitsu Takizawa and Akira Tangoku : 診断に苦慮したmicronodular thymic carcinomaの1例, 第40回日本胸腺研究会, Feb. 2021.
160.	Kyoka Muguruma, Kazuya Kondo, Shiho Soejima, Birgun Tegsee, Michiko Yamashita, 岸渕麗奈, Mitsuhiro Tsuboi, Koichiro Kajiura, Yukikiyo Kawakami, Naoya Kawakita, Hiroaki Toba, Mitsuteru Yoshida, Hiromitsu Takizawa and Akira Tangoku : 胸腺上皮性腫瘍におけるMT1A遺伝子のDNAメチル化とmRNA発現, 第40回日本胸腺研究会, Feb. 2021.
161.	Mitsuteru Yoshida, Kazuya Kondo, Yoshimi Bando, 竹原恵美, 宮本直輝, 坂本晋一, Mika Takashima, Daisuke Matsumoto, Naoya Kawakita, Hiroaki Toba, Yukikiyo Kawakami, Hiromitsu Takizawa and Akira Tangoku : 診断と治療に苦慮した前縦隔粘液線維肉腫の経験, 第61回日本肺癌学会学術集会(ハイブリッド形式), Nov. 2020.
162.	副島志帆, Kazuya Kondo, Mitsuhiro Tsuboi, Koichiro Kajiura, 六車京香, Yukikiyo Kawakami, Naoya Kawakita, Hiroaki Toba, Mitsuteru Yoshida, Hiromitsu Takizawa and Akira Tangoku : 胸腺上皮性腫瘍の悪性度とGAD1遺伝子のDNAメチル化と発現, 第61回日本肺癌学会学術集会(ハイブリッド形式), Nov. 2020.
163.	Rinen Choh, Kazuya Kondo, Takae Bando, Yoshie Imai, Aki Takahashi, 荒堀広美, YAO RENYIN, Hiromitsu Takizawa, Yukikiyo Kawakami, Mitsuteru Yoshida, Hiroaki Toba, Mitsuhiro Tsuboi and Akira Tangoku : 手術療法施行した肺がん患者におけるpatient reported quality of life(PRQOL)の評価, 第61回日本肺癌学会学術集会(ハイブリッド形式), Nov. 2020.
164.	Hiromitsu Takizawa, 庄野隆志, 南城和正, Hidenori Maki, 山本清成, 坂本晋一, 宮本直輝, Mika Takashima, Daisuke Matsumoto, Naoya Kawakita, Hiroaki Toba, Yukikiyo Kawakami, Mitsuteru Yoshida, Kazuya Kondo and Akira Tangoku : 蛍光顕微鏡を用いた小型肺腺癌浸潤診断についての検討, 第61回日本肺癌学会学術集会(ハイブリッド形式), Nov. 2020.
165.	Daisuke Matsumoto, Hiroaki Toba, 庄野隆志, 南城和正, Hidenori Maki, 山本清成, 坂本晋一, 宮本直輝, Mika Takashima, Naoya Kawakita, Yukikiyo Kawakami, Mitsuteru Yoshida, Hiromitsu Takizawa, Kazuya Kondo and Akira Tangoku : 切除可能cI-ⅢA期肺扁平上皮癌における術後再発リスクの層別化と治療戦略, 第61回日本肺癌学会学術集会(ハイブリッド形式), Nov. 2020.
166.	Mika Takashima, Hiroaki Toba, 庄野隆志, 南城和正, Hidenori Maki, 山本清成, 坂本晋一, 宮本直輝, Daisuke Matsumoto, Naoya Kawakita, Yukikiyo Kawakami, Mitsuteru Yoshida, Hiromitsu Takizawa, Kazuya Kondo and Akira Tangoku : アダプター蛋白XB130はⅠ期肺腺癌の予後因子となり得る, 第61回日本肺癌学会学術集会(ハイブリッド形式), Nov. 2020.
167.	Naoya Kawakita, Hiroaki Toba, Hiromitsu Takizawa, 南城和正, 庄野隆志, Hidenori Maki, 山本清成, 坂本晋一, 宮本直輝, Mika Takashima, Daisuke Matsumoto, Yukikiyo Kawakami, Mitsuteru Yoshida, Kazuya Kondo and Akira Tangoku : 小型末梢肺癌診断率向上のためのCone-beam CT併用極細径気管支鏡下生検, 第61回日本肺癌学会学術集会(ハイブリッド形式), Nov. 2020.
168.	Tegshee Bilguun, Kazuya Kondo, Soejima Shiho, Muguruma Kyoka, Mitsuhiro Tsuboi, Koichiro Kajiura, Yukikiyo Kawakami, Naoya Kawakita, Toru Sawada, Hiroaki Toba, Mitsuteru Yoshida, Hiromitsu Takizawa and Akira Tangoku : Expression of variant ligand and receptor of Ghrelin system is related to tumorigenesis of thymoma, 第61回日本肺癌学会学術集会(ハイブリッド形式), Nov. 2020.
169.	Hiroaki Toba, Hiromitsu Takizawa, 坂本晋一, 宮本直輝, Mika Takashima, Daisuke Matsumoto, Naoya Kawakita, Yukikiyo Kawakami, Mitsuteru Yoshida, Kazuya Kondo and Akira Tangoku : 高齢肺癌患者を地域で役割分担して診るための包括的な取り組み, 第61回日本肺癌学会学術集会(ハイブリッド形式), Nov. 2020.
170.	南城和正, Mitsuteru Yoshida, Momoyo Azuma, 庄野隆志, 山本清成, Hidenori Maki, 宮本直輝, 坂本晋一, Mika Takashima, Daisuke Matsumoto, Naoya Kawakita, Hiroaki Toba, Yukikiyo Kawakami, Hiromitsu Takizawa and Akira Tangoku : 呼吸器外科からみた結核スクリーニング-T-SPOT検査は有用か-, 第73回日本胸部外科学会定期学術集会(Web開催), Oct. 2020.
171.	宮本直輝, 南城和正, 坂本晋一, Mika Takashima, Daisuke Matsumoto, Naoya Kawakita, Hiroaki Toba, Yukikiyo Kawakami, Mitsuteru Yoshida, Kazuya Kondo, Hiromitsu Takizawa and Akira Tangoku : 原発性肺癌術後オリゴ肺転移症例についての検討, 第73回日本胸部外科学会定期学術集会(Web開催), Oct. 2020.
172.	Seiya Inoue, Takahiro Yoshida, Takeshi Nishino, Masakazu Goto, Mariko Aoyama, Naoya Kawakita, Hiromitsu Takizawa and Akira Tangoku : 生検組織を用いた食道扁平上皮癌に対する初回化学療法の効果と予後予測因子の解明, 第73回日本胸部外科学会定期学術集会(Web開催), Oct. 2020.
173.	山本清成, Takeshi Nishino, 庄野隆志, 南城和正, Hidenori Maki, Mika Takashima, Daisuke Matsumoto, Naoya Kawakita, Seiya Inoue, Masakazu Goto, Takahiro Yoshida, Hiroaki Toba, Mitsuteru Yoshida, Hiromitsu Takizawa and Akira Tangoku : 気管分岐部狭窄を伴う気管支瘻形成進行食道癌に対する集学的治療の経験, 第73回日本胸部外科学会定期学術集会(Web開催), Oct. 2020.
174.	Hiromitsu Takizawa, 南城和正, 庄野隆志, 山本清成, Hidenori Maki, 宮本直輝, 坂本晋一, Mika Takashima, Daisuke Matsumoto, Naoya Kawakita, Hiroaki Toba, Yukikiyo Kawakami, Mitsuteru Yoshida, Kazuya Kondo and Akira Tangoku : CTリンパ管造影による肺癌センチネルリンパ節マップの検討, 第73回日本胸部外科学会定期学術集会(Web開催), Oct. 2020.
175.	Mitsuteru Yoshida, Kazuya Kondo, Takashi Kitaichi, Takeshi Oya, Minoru Matsumoto, 宮本直輝, 南城和正, 庄野隆志, Hidenori Maki, 山本清成, 坂本晋一, Mika Takashima, Daisuke Matsumoto, Naoya Kawakita, Hiroaki Toba, Yukikiyo Kawakami, Hiromitsu Takizawa and Akira Tangoku : 分類不能型縦隔高悪性度腫瘍の手術例の経験, 第73回日本胸部外科学会定期学術集会(Web開催), Oct. 2020.
176.	Takahiro Yoshida, Takeshi Nishino, Seiya Inoue, Masakazu Goto, Akira Tangoku, Yoshihiro Tsuruo, Mariko Aoyama, Hiroaki Toba and Hiromitsu Takizawa : 食道外科手術におけるカダバートレーニングの経験と展望, 第73回日本胸部外科学会定期学術集会(Web開催), Oct. 2020.
177.	Mika Takashima, Hiroaki Toba, Hiromitsu Takizawa, 坂本晋一, 宮本直輝, Daisuke Matsumoto, Naoya Kawakita, Yukikiyo Kawakami, Mitsuteru Yoshida, Kazuya Kondo and Akira Tangoku : 地方で働く一呼吸器外科医としての現在地，そしてこれから, 第73回日本胸部外科学会定期学術集会(Web開催), Oct. 2020.
178.	Hiromitsu Takizawa : 《スポンサードセミナー》ICGを用いた気管支動脈の術中同定, 第73回日本胸部外科学会定期学術集会, Oct. 2020.
179.	南城和正, Naoya Kawakita, Mitsuteru Yoshida, 庄野隆志, 山本清成, Hidenori Maki, Shinichi Sakamoto, Naoki Miyamoto, Mika Takashima, Daisuke Matsumoto, Hiroaki Toba, Yukikiyo Kawakami, Hiromitsu Takizawa, Kazuya Kondo and Akira Tangoku : 肺アミロイドーシスを伴った上皮内肺腺癌の1例, 第95回中国四国外科学会総会・第25回中国四国内視鏡外科研究会(Web開催), Oct. 2020.
180.	Shinichi Sakamoto, Koichiro Kenzaki, 久保尊子, 法村尚子, Hiroaki Toba, Mitsuteru Yoshida, Hiromitsu Takizawa, 三浦一真 and Akira Tangoku : ロボット支援下肺葉切除術導入における助手の役割, 第95回中国四国外科学会総会・第25回中国四国内視鏡外科研究会(Web開催), Oct. 2020.
181.	Hidenori Maki, Hiromitsu Takizawa, 庄野隆志, 南城和正, 山本清成, Shinichi Sakamoto, Naoki Miyamoto, Daisuke Matsumoto, Mika Takashima, Naoya Kawakita, Hiroaki Toba, Mitsuteru Yoshida, Yukikiyo Kawakami, Kazuya Kondo and Akira Tangoku : 微小肺病変に対して術中Cone-beam CT併用気管支鏡下コイルマーキングが有用であった1例, 第95回中国四国外科学会総会・第25回中国四国内視鏡外科研究会(Web開催), Oct. 2020.
182.	宮本直輝, 南城和正, Hidenori Maki, Shinichi Sakamoto, Mika Takashima, Daisuke Matsumoto, Naoya Kawakita, Hiroaki Toba, Yukikiyo Kawakami, Mitsuteru Yoshida, Hiromitsu Takizawa, Kazuya Kondo and Akira Tangoku : 胸腔鏡下に確定診断を得たCalcifying fibrous tumorの1例, 第95回中国四国外科学会総会・第25回中国四国内視鏡外科研究会(Web開催), Oct. 2020.
183.	Mariko Aoyama, Hiromitsu Takizawa, Mitsuhiro Tsuboi and Akira Tangoku : 甲状腺未分化癌同所移植マウスモデルと小動物用FDG-PET/CTを用いた分子標的治療効果判定法の確立, 第24回日本がん分子標的治療学会学術集会(ハイブリッド形式), Oct. 2020.
184.	Mika Takashima, Hiroaki Toba, Kai Mizobuchi, 竹原恵美, Naoki Miyamoto, Daisuke Matsumoto, Naoya Kawakita, Mitsuhiro Tsuboi, Yukikiyo Kawakami, Mitsuteru Yoshida, Hiromitsu Takizawa, Kazuya Kondo and Akira Tangoku : 神経線維腫症1型を背景とした肋間動脈瘤破裂による血胸に対しソフト凝固により止血し得た1例, 第37回日本呼吸器外科学会学術集会(Web開催), Sep. 2020.
185.	Hiromitsu Takizawa, Kai Mizobuchi, 竹原恵美, 宮本直輝, Mika Takashima, Daisuke Matsumoto, Naoya Kawakita, Mitsuhiro Tsuboi, Hiroaki Toba, Mitsuteru Yoshida, Yukikiyo Kawakami, Kazuya Kondo and Akira Tangoku : 大腸癌肺転移の肺切除後再発リスク因子, 第37回日本呼吸器外科学会学術集会(Web開催), Sep. 2020.
186.	Naoya Kawakita, Hiroaki Toba, Kai Mizobuchi, 竹原恵美, Naoki Miyamoto, Daisuke Matsumoto, Mika Takashima, Mitsuhiro Tsuboi, Yukikiyo Kawakami, Mitsuteru Yoshida, Hiromitsu Takizawa, Kazuya Kondo and Akira Tangoku : ステロイドが遷延性肺瘻に与える影響, 第37回日本呼吸器外科学会学術集会(Web開催), Sep. 2020.
187.	Daisuke Matsumoto, Hiroaki Toba, Kai Mizobuchi, 竹原恵美, Naoki Miyamoto, Mika Takashima, Naoya Kawakita, Mitsuhiro Tsuboi, Yukikiyo Kawakami, Mitsuteru Yoshida, Hiromitsu Takizawa, Kazuya Kondo and Akira Tangoku : コイルと色素を併用した気管支鏡下コイルマーキング法による，触知困難小型病変に対する単孔式胸腔鏡下肺部分切除, 第37回日本呼吸器外科学会学術集会(Web開催), Sep. 2020.
188.	Hiroaki Toba, Hiromitsu Takizawa, Naoki Miyamoto, Mika Takashima, Daisuke Matsumoto, Naoya Kawakita, Mitsuhiro Tsuboi, Yukikiyo Kawakami, Mitsuteru Yoshida, Kazuya Kondo and Akira Tangoku : かかりつけ医と連携してより良い肺癌診療をするための包括的な取り組み, 第37回日本呼吸器外科学会学術集会(Web開催), Sep. 2020.
189.	Mitsuhiro Tsuboi, Kazuya Kondo, Kai Mizobuchi, 竹原恵美, Naoki Miyamoto, Mika Takashima, Daisuke Matsumoto, Naoya Kawakita, Hiroaki Toba, Yukikiyo Kawakami, Mitsuteru Yoshida, Hiromitsu Takizawa and Akira Tangoku : 進行期胸腺上皮性腫瘍の治療成績の検討, 第37回日本呼吸器外科学会学術集会(Web開催), Sep. 2020.
190.	Mitsuteru Yoshida, Kazuya Kondo, Tamaki Otani, Hirohisa Ogawa, Naoki Miyamoto, 竹原恵美, Mika Takashima, Daisuke Matsumoto, Naoya Kawakita, Mitsuhiro Tsuboi, Hiroaki Toba, Yukikiyo Kawakami, Hiromitsu Takizawa and Akira Tangoku : 呼吸器外科の癌免疫療法研究-CMT167マウス肺癌細胞株同所移植モデルマウスの確立に向けて-, 第37回日本呼吸器外科学会学術集会(Web開催), Sep. 2020.
191.	Kai Mizobuchi, Mitsuteru Yoshida, Kazuya Kondo, Takashi Kitaichi, Takeshi Oya, Minoru Matsumoto, 竹原恵美, Naoki Miyamoto, Mika Takashima, Daisuke Matsumoto, Naoya Kawakita, Mitsuhiro Tsuboi, Hiroaki Toba, Yukikiyo Kawakami, Hiromitsu Takizawa and Akira Tangoku : 前縦隔に発生した分類不能型高悪性度腫瘍の一切除例, 第37回日本呼吸器外科学会学術集会(Web開催), Sep. 2020.
192.	Mariko Aoyama, Hiromitsu Takizawa, Kai Mizobuchi, 竹原恵美, Naoki Miyamoto, Mitsuhiro Tsuboi and Akira Tangoku : 自家蛍光による副甲状腺の同定-励起光による自家蛍光の変化に注目して-, 第32回日本内分泌外科学会総会, Sep. 2020.
193.	Mariko Aoyama, Hiromitsu Takizawa, Seiya Inoue, Naoya Kawakita, Mitsuhiro Tsuboi, Kazuya Kondo and Akira Tangoku : 小動物用FDG-PET/CTを使用した甲状腺未分化癌の同所移植マウスモデルの作成, 第120回日本外科学会定期学術集会(Web開催), Aug. 2020.
194.	Daisuke Matsumoto, Naoya Kawakita, Hiromitsu Takizawa, Kai Mizobuchi, 竹原恵美, Naoki Miyamoto, Mika Takashima, Mitsuhiro Tsuboi, Hiroaki Toba, Yukikiyo Kawakami, Mitsuteru Yoshida, Kazuya Kondo and Akira Tangoku : 気管支鏡処置を要する術後無気肺発症のハイリスク患者群の抽出, 第43回日本呼吸器内視鏡学会学術集会(紙上開催), Jun. 2020.
195.	Hiromitsu Takizawa, Naoya Kawakita, Eman Ali, Mitsuhiro Tsuboi, Kai Mizobuchi, 竹原恵美, Naoki Miyamoto, Mika Takashima, Daisuke Matsumoto, Hiroaki Toba, Yukikiyo Kawakami, Mitsuteru Yoshida, Kazuya Kondo and Akira Tangoku : 当科における経気管支生検時併用モダリティ別の診断成績比較Cone-beam CT vs EBUS-GS, 第43回日本呼吸器内視鏡学会学術集会(紙上開催), Jun. 2020.
196.	Naoya Kawakita, Hiromitsu Takizawa, Kai Mizobuchi, 竹原恵美, Naoki Miyamoto, Mika Takashima, Daisuke Matsumoto, Mitsuhiro Tsuboi, Hiroaki Toba, Yukikiyo Kawakami, Mitsuteru Yoshida, Kazuya Kondo and Akira Tangoku : Cone-beam CTを用いた極細径気管支鏡下生検, 第43回日本呼吸器内視鏡学会学術集会(紙上開催), Jun. 2020.
197.	Mika Takashima, Hiroaki Toba, Kai Mizobuchi, 竹原恵美, Naoki Miyamoto, Daisuke Matsumoto, Naoya Kawakita, Mitsuhiro Tsuboi, Yukikiyo Kawakami, Mitsuteru Yoshida, Hiromitsu Takizawa, Kazuya Kondo and Akira Tangoku : 進行食道癌による気道狭窄に対するステント留置例の検討, 第43回日本呼吸器内視鏡学会学術集会(紙上開催), Jun. 2020.
198.	Mitsuteru Yoshida, Kazuhide Mineda, Naoya Kawakita, Kazuya Kondo, Kai Mizobuchi, 竹原恵美, Naoki Miyamoto, Mika Takashima, Daisuke Matsumoto, Mitsuhiro Tsuboi, Hiroaki Toba, Yukikiyo Kawakami, Hiromitsu Takizawa and Akira Tangoku : 皮膚移植とBACシステムを組み合わせた有瘻性膿胸の治療経験-開創術後のマネジメントにいかに立ち向かうか, 第43回日本呼吸器内視鏡学会学術集会(紙上開催), Jun. 2020.
199.	副島志帆, Kazuya Kondo, 六車京香, Mitsuhiro Tsuboi, Koichiro Kajiura, Yukikiyo Kawakami, Naoya Kawakita, Toru Sawada, Hiroaki Toba, Mitsuteru Yoshida, Hiromitsu Takizawa and Akira Tangoku : 胸腺上皮性腫瘍におけるghrelin-GHSR系分子の発現, 第39回日本胸腺研究会, Feb. 2020.
200.	六車京香, Kazuya Kondo, 副島志帆, 岸渕麗奈, Mitsuhiro Tsuboi, Koichiro Kajiura, Yukikiyo Kawakami, Naoya Kawakita, Hiroaki Toba, Mitsuteru Yoshida, Hiromitsu Takizawa and Akira Tangoku : 胸腺上皮性腫瘍におけるNPTX2遺伝子のDNAメチル化とmRNA，タンパク発現の関係, 第39回日本胸腺研究会, Feb. 2020.
201.	Mitsuteru Yoshida, Kazuya Kondo, Takashi Kitaichi, Takeshi Oya, Minoru Matsumoto, 宮本直輝, 鈴木恵美, 高嶋美佳, 松本大資, Naoya Kawakita, Mitsuhiro Tsuboi, Hiroaki Toba, Yukikiyo Kawakami, Hiromitsu Takizawa and Akira Tangoku : 前縦隔に発生した分類不能型高悪性度腫瘍の一切除例, 第39回日本胸腺研究会, Feb. 2020.
202.	Mika Takashima, Hiroaki Toba, Souji Kakiuchi, Naoki Miyamoto, Daisuke Matsumoto, Naoya Kawakita, Mitsuhiro Tsuboi, Yukikiyo Kawakami, Mitsuteru Yoshida, Hiromitsu Takizawa, Kazuya Kondo and Akira Tangoku : 気管瘻を伴った進行肺癌による気道狭窄に対し気道ステント留置により長期にわたり良好なQOLを維持できた1例, 第60回日本肺癌学会学術集会, Dec. 2019.
203.	Mitsuteru Yoshida, Hirohisa Ogawa, 湯浅将生, 竹原恵美, Naoki Miyamoto, Mika Takashima, Daisuke Matsumoto, Naoya Kawakita, Mitsuhiro Tsuboi, Hiroaki Toba, Yukikiyo Kawakami, Hiromitsu Takizawa, Kazuya Kondo and Akira Tangoku : 定量的三次元CT解析から上皮内癌，微小浸潤癌を予測できるか, 第60回日本肺癌学会学術集会, Dec. 2019.
204.	Mitsuhiro Tsuboi, Kazuya Kondo, 副島志帆, 六車京香, Kai Mizobuchi, 竹原恵美, 宮本直輝, 高嶋美佳, 松本大資, Naoya Kawakita, Hiroaki Toba, Yukikiyo Kawakami, Mitsuteru Yoshida, Hiromitsu Takizawa and Akira Tangoku : クロム工場従事者の肺癌におけるMLH1遺伝子のメチル化の検討, 第60回日本肺癌学会学術集会, Dec. 2019.
205.	副島志帆, Kazuya Kondo, 岸渕麗奈, 六車京香, Mitsuhiro Tsuboi, Koichiro Kajiura, Birgun Tegsee, Yukikiyo Kawakami, Naoya Kawakita, Hiroaki Toba, Mitsuteru Yoshida, Hiromitsu Takizawa and Akira Tangoku : 胸腺上皮性腫瘍の悪性度の指標としてのGHSRのDNAメチル化, 第60回日本肺癌学会学術集会, Dec. 2019.
206.	六車京香, Kazuya Kondo, 副島志帆, 岸渕麗奈, Bilguunmin Tegshee, Mitsuhiro Tsuboi, Koichiro Kajiura, Yukikiyo Kawakami, Naoya Kawakita, Hiroaki Toba, Mitsuteru Yoshida, Hiromitsu Takizawa and Akira Tangoku : 胸腺上皮性腫瘍におけるMT1AとNPTX2遺伝子のDNAメチル化とmRNAの発現の関係, 第60回日本肺癌学会学術集会, Dec. 2019.
207.	Daisuke Matsumoto, Hiroaki Toba, Kazuya Kondo, Kai Mizobuchi, 竹原恵美, Naoki Miyamoto, Mika Takashima, Naoya Kawakita, Mitsuhiro Tsuboi, Yukikiyo Kawakami, Mitsuteru Yoshida, Hiromitsu Takizawa and Akira Tangoku : 右肺動脈閉鎖症を伴う右下葉肺癌に対し，胸腔鏡下肺葉切除を行った1例, 第60回日本肺癌学会学術集会, Dec. 2019.
208.	Hiromitsu Takizawa, 竹原恵美, Naoki Miyamoto, Mika Takashima, Daisuke Matsumoto, Naoya Kawakita, Mitsuhiro Tsuboi, Hiroaki Toba, Mitsuteru Yoshida, Yukikiyo Kawakami, Kazuya Kondo and Akira Tangoku : 蛍光顕微鏡を用いた肺腺癌浸潤診断についての検討, 第60回日本肺癌学会学術集会, Dec. 2019.
209.	Naoki Miyamoto, Mitsuteru Yoshida, Mika Takashima, Daisuke Matsumoto, Naoya Kawakita, Mitsuhiro Tsuboi, Hiroaki Toba, Yukikiyo Kawakami, Kazuya Kondo, Hiromitsu Takizawa and Akira Tangoku : 胸腔鏡下生検で確定診断を得たCalcifying fibrous tumorの1例, 第62回日本呼吸器学会中国・四国地方会, Nov. 2019.
210.	竹原恵美, Hiroaki Toba, Kai Mizobuchi, 宮本直輝, 高嶋美佳, 松本大資, Naoya Kawakita, Mitsuhiro Tsuboi, Mitsuteru Yoshida, Yukikiyo Kawakami, Hiromitsu Takizawa, Kazuya Kondo and Akira Tangoku : ニボルマブが奏功し，長期間休止後増悪時に再投与した切除不能肺癌の1例, 第81回日本臨床外科学会総会, Nov. 2019.
211.	Hiroaki Toba, Hiromitsu Takizawa, Takahiro Yoshida, Masami Morimoto, 青山万理子, Hirokazu Takechi and Akira Tangoku : がんの地域連携におけるかかりつけ医とのより早期からの情報交換と役割分担の重要性∼患者にとって良い連携体制構築のための包括的な取り組み, 第81回日本臨床外科学会総会, Nov. 2019.
212.	Hiromitsu Takizawa, Hiroaki Toba, Daisuke Matsumoto, 竹原恵美, Naoki Miyamoto, Mika Takashima, Naoya Kawakita, Mitsuhiro Tsuboi, Mitsuteru Yoshida, Yukikiyo Kawakami, Kazuya Kondo and Akira Tangoku : 《クリニカルビデオセッション》胸腔シミュレータと3D臓器モデルを用いたロボット支援胸腔鏡下肺葉切除の術前トレーニング, 第72回日本胸部外科学会定期学術集会, Oct. 2019.
213.	Mitsuteru Yoshida, Hirohisa Ogawa, 湯浅将生, 鈴木恵美, Naoki Miyamoto, Mika Takashima, Daisuke Matsumoto, Naoya Kawakita, Mitsuhiro Tsuboi, Hiroaki Toba, Yukikiyo Kawakami, Hiromitsu Takizawa, Kazuya Kondo and Akira Tangoku : 上皮内癌，微小浸潤癌の三次元画像解析, 第72回日本胸部外科学会定期学術集会, Oct. 2019.
214.	Takahiro Yoshida, Takeshi Nishino, Seiya Inoue, Masakazu Goto, Mika Takashima, Hiroaki Toba, Hiromitsu Takizawa and Akira Tangoku : 《パネルディスカッション》隣接臓器浸潤を伴う局所進行食道癌に対する集学的治療Oncological Emergencyへの対応と食道バイパス手術併用によるQOLの評価, 第72回日本胸部外科学会定期学術集会, Oct. 2019.
215.	Naoya Kawakita, Hiromitsu Takizawa, 竹原恵美, Naoki Miyamoto, Mika Takashima, Daisuke Matsumoto, Mitsuhiro Tsuboi, Hiroaki Toba, Mitsuteru Yoshida, Yukikiyo Kawakami, Kazuya Kondo and Akira Tangoku : 肝細胞癌肺転移に対するインドシアニングリーン蛍光下手術, 第57回日本癌治療学会学術集会, Oct. 2019.
216.	Toru Sawada, Hiromitsu Takizawa, Mariko Aoyama, 竹原恵美, Mika Takashima, Daisuke Matsumoto, Naoya Kawakita, Mitsuhiro Tsuboi, Hiroaki Toba, Mitsuteru Yoshida, Yukikiyo Kawakami, Kazuya Kondo and Akira Tangoku : 共焦点レーザー内視鏡における肺癌胸膜浸潤診断の有用性について, 第57回日本癌治療学会学術集会, Oct. 2019.
217.	青山万理子, Hiromitsu Takizawa, Mitsuhiro Tsuboi and Akira Tangoku : 甲状腺原発悪性リンパ腫の診断における穿刺吸引細胞診の有用性について, 第52回日本内分泌外科学会学術集会, Oct. 2019.
218.	Mitsuhiro Tsuboi, 青山万理子, Hiromitsu Takizawa and Akira Tangoku : 3mm assist portを併用した内視鏡下甲状腺悪性腫瘍手術, 第52回日本内分泌外科学会学術集会, Oct. 2019.
219.	Mariko Aoyama, Hiromitsu Takizawa, Kai Mizobuchi, 竹原恵美, Mitsuhiro Tsuboi and Akira Tangoku : 内科治療抵抗性のBasedow病に手術を施行した1例, 第94回中国四国外科学会総会・第24回中国四国内視鏡外科研究会, Sep. 2019.
220.	Hiromitsu Takizawa, Hiroaki Toba, Daisuke Matsumoto, Mika Takashima, 竹原恵美, Naoki Miyamoto, Naoya Kawakita, Mitsuhiro Tsuboi, Mitsuteru Yoshida, Yukikiyo Kawakami, Kazuya Kondo and Akira Tangoku : ロボット支援胸腔鏡下肺葉切除導入期における3D臓器モデルを用いた術前シミュレーション, 第94回中国四国外科学会総会・第24回中国四国内視鏡外科研究会, Sep. 2019.
221.	竹原恵美, Hiromitsu Takizawa, Kai Mizobuchi, Naoki Miyamoto, Mika Takashima, Daisuke Matsumoto, Naoya Kawakita, Mitsuhiro Tsuboi, Hiroaki Toba, Yukikiyo Kawakami, Mitsuteru Yoshida, Kazuya Kondo and Akira Tangoku : 卒後3年目後期研修医が経験した胸腔鏡下肺悪性腫瘍手術の修練, 第94回中国四国外科学会総会・第24回中国四国内視鏡外科研究会, Sep. 2019.
222.	Hiroaki Toba, Hiromitsu Takizawa, Takahiro Yoshida, Masami Morimoto, Mariko Aoyama, Hirokazu Takechi and Akira Tangoku : より良いがんの地域連携体制構築のためのmulti-modalな取り組み, 第94回中国四国外科学会総会・第24回中国四国内視鏡外科研究会, Sep. 2019.
223.	Mitsuteru Yoshida, 山上真樹子, Akira Tangoku, Takashi Kitaichi, Masaaki Nishi, Hiromitsu Takizawa, Hiroki Ishibashi and Mitsuo Shimada : 徳島大学外科専門医研修プログラムの現状と今後の課題, 第94回中国四国外科学会総会・第24回中国四国内視鏡外科研究会, Sep. 2019.
224.	竹原恵美, Hiromitsu Takizawa, 宮本直輝, 高嶋美佳, 松本大資, Naoya Kawakita, Mitsuhiro Tsuboi, Hiroaki Toba, Mitsuteru Yoshida, Yukikiyo Kawakami, Kazuya Kondo and Akira Tangoku : 急速増大を示したLCNECの一切除例, 第58回日本肺癌学会中国・四国支部学術集会, Jul. 2019.
225.	Mitsuhiro Tsuboi, Naoya Kawakita, Hiromitsu Takizawa, 鈴木恵美, Ryo Yamada, Mika Takashima, Daisuke Matsumoto, Toru Sawada, Hiroaki Toba, Yukikiyo Kawakami, Mitsuteru Yoshida, Kazuya Kondo and Akira Tangoku : 極細径気管支鏡下肺生検における到達困難な末梢病変の検討, 第42回日本呼吸器内視鏡学会学術集会, Jul. 2019.
226.	Toru Sawada, Hiromitsu Takizawa, 鈴木恵美, Ryo Yamada, Mika Takashima, Daisuke Matsumoto, Naoya Kawakita, Mitsuhiro Tsuboi, Hiroaki Toba, Mitsuteru Yoshida, Yukikiyo Kawakami, Kazuya Kondo and Akira Tangoku : 共焦点レーザー内視鏡による肺癌胸膜浸潤診断, 第42回日本呼吸器内視鏡学会学術集会, Jul. 2019.
227.	Hiromitsu Takizawa, Hiroaki Toba, 松本大資, Ryo Yamada, 鈴木恵美, Mika Takashima, Naoya Kawakita, Toru Sawada, Mitsuhiro Tsuboi, Mitsuteru Yoshida, Yukikiyo Kawakami, Kazuya Kondo and Akira Tangoku : ロボット支援胸腔鏡下手術導入における3D臓器モデルを用いた術前トレーニング, 第42回日本呼吸器内視鏡学会学術集会, Jul. 2019.
228.	Mika Takashima, Hiroaki Toba, 鈴木恵美, Ryo Yamada, Daisuke Matsumoto, Naoya Kawakita, Toru Sawada, Mitsuhiro Tsuboi, Yukikiyo Kawakami, Mitsuteru Yoshida, Hiromitsu Takizawa, Kazuya Kondo and Akira Tangoku : 食道気管支瘻を伴った食道癌による気管分岐部狭窄に対し気道ステント留置が有効であった1例, 第42回日本呼吸器内視鏡学会学術集会, Jul. 2019.
229.	Mitsuteru Yoshida, Takashi Iwata, Masashi Akaike, 鈴木恵美, Ryo Yamada, Mika Takashima, Daisuke Matsumoto, Naoya Kawakita, Toru Sawada, Mitsuhiro Tsuboi, Hiroaki Toba, Yukikiyo Kawakami, Hiromitsu Takizawa, Kazuya Kondo, Akira Tangoku and Yoshihiro Tsuruo : 《ワークショップ》外科手術教育の当院における取り組み, 第42回日本呼吸器内視鏡学会学術集会, Jul. 2019.
230.	Ryo Yamada, Mitsuteru Yoshida, Naoya Kawakita, 鈴木恵美, Mika Takashima, Daisuke Matsumoto, Toru Sawada, Mitsuhiro Tsuboi, Hiroaki Toba, Yukikiyo Kawakami, Hiromitsu Takizawa, Kazuya Kondo and Akira Tangoku : 肺癌との鑑別に苦慮した，気管内過誤腫による閉塞性肺炎の一切除例, 第42回日本呼吸器内視鏡学会学術集会, Jul. 2019.
231.	鈴木恵美, Naoya Kawakita, Ryo Yamada, Daisuke Matsumoto, Mika Takashima, Toru Sawada, Mitsuhiro Tsuboi, Hiroaki Toba, Mitsuteru Yoshida, Hiromitsu Takizawa, Kazuya Kondo and Akira Tangoku : 高齢者気管支脂肪腫に対し気管支鏡下に切除を行った一例, 第42回日本呼吸器内視鏡学会学術集会, Jul. 2019.
232.	Hiroaki Toba, 六田暉朗, Mika Takashima, Daisuke Matsumoto, Toru Sawada, Naoya Kawakita, Mitsuhiro Tsuboi, Yukikiyo Kawakami, Mitsuteru Yoshida, Hiromitsu Takizawa, Kazuya Kondo and Akira Tangoku : 気管支鏡検査用局所麻酔薬噴霧カテーテルスプレーの有用性-第2報-, 第42回日本呼吸器内視鏡学会学術集会, Jul. 2019.
233.	Daisuke Matsumoto, Hiromitsu Takizawa, 鈴木恵美, Ryo Yamada, Mika Takashima, Naoya Kawakita, Toru Sawada, Mitsuhiro Tsuboi, Hiroaki Toba, Yukikiyo Kawakami, Mitsuteru Yoshida, Kazuya Kondo and Akira Tangoku : 触知困難小型肺病変に対するコイルと色素を用いたマーキング法, 第42回日本呼吸器内視鏡学会学術集会, Jul. 2019.
234.	Naoya Kawakita, Hiromitsu Takizawa, 鈴木恵美, Ryo Yamada, Mika Takashima, Daisuke Matsumoto, Toru Sawada, Mitsuhiro Tsuboi, Hiroaki Toba, Yukikiyo Kawakami, Mitsuteru Yoshida, Kazuya Kondo and Akira Tangoku : Cone-beam CTを用いた極細径気管支鏡下生検の現状と展望, 第42回日本呼吸器内視鏡学会学術集会, Jul. 2019.
235.	Mitsuhiro Tsuboi, Mariko Aoyama, Hiromitsu Takizawa and Akira Tangoku : 悪性を疑う濾胞性腫瘍の検査所見の検討, 第31回日本内分泌外科学会総会, Jun. 2019.
236.	Mariko Aoyama, Hiromitsu Takizawa, Mitsuhiro Tsuboi and Akira Tangoku : 甲状腺原発悪性リンパ腫の診断における穿刺吸引細胞診の有用性についての検討, 第31回日本内分泌外科学会総会, Jun. 2019.
237.	Mika Takashima, 鈴木恵美, Ryo Yamada, Daisuke Matsumoto, Naoya Kawakita, Toru Sawada, Mitsuhiro Tsuboi, Hiroaki Toba, Yukikiyo Kawakami, Mitsuteru Yoshida, Hiromitsu Takizawa, Kazuya Kondo and Akira Tangoku : 当科における前縦隔腫瘍に対する手術アプローチ法の検討, 第62回関西胸部外科学会学術集会, Jun. 2019.
238.	Mitsuteru Yoshida, Kazuya Kondo, 湯浅将生, 池光大貴, Toru Sawada, 鈴木恵美, Ryo Yamada, Mika Takashima, Daisuke Matsumoto, Naoya Kawakita, Mitsuhiro Tsuboi, Hiroaki Toba, Yukikiyo Kawakami, Hiromitsu Takizawa and Akira Tangoku : 胸腺手術手技の3D CT画像による評価-胸骨正中切開と剣状突起下アプローチの比較検討-, 第62回関西胸部外科学会学術集会, Jun. 2019.
239.	Mika Takashima, Hiroaki Toba, Soichiroh Sasa, Daisuke Matsumoto, Seiya Inoue, Naoya Kawakita, Toru Sawada, Takeshi Nishino, Mitsuhiro Tsuboi, Yukikiyo Kawakami, Takahiro Yoshida, Mitsuteru Yoshida, Hiromitsu Takizawa, Kazuya Kondo and Akira Tangoku : 食道気管支瘻を伴った食道癌による気管分岐部狭窄に対し気道ステント留置が有効であった1例, 第62回関西胸部外科学会学術集会, Jun. 2019.
240.	Naoya Kawakita, Hiromitsu Takizawa, Kazuya Kondo, 鈴木恵美, Ryo Yamada, Toru Sawada, Mitsuhiro Tsuboi, Hiroaki Toba, Yukikiyo Kawakami, Mitsuteru Yoshida and Akira Tangoku : 横隔膜交通症に対するICG蛍光ガイド下手術の2例, 第62回関西胸部外科学会学術集会, Jun. 2019.
241.	Hiromitsu Takizawa, Hiroaki Toba, Daisuke Matsumoto, Ryo Yamada, 鈴木恵美, Mika Takashima, Naoya Kawakita, Toru Sawada, Mitsuhiro Tsuboi, Mitsuteru Yoshida, Yukikiyo Kawakami, Kazuya Kondo and Akira Tangoku : ロボット支援胸腔鏡下手術導入における3D臓器モデルとスキルシミュレータの活用, 第36回日本呼吸器外科学会総会, May 2019.
242.	鈴木恵美, Mitsuteru Yoshida, Momoyo Azuma, Ryo Yamada, Daisuke Matsumoto, Mika Takashima, Toru Sawada, Naoya Kawakita, Mitsuhiro Tsuboi, Hiroaki Toba, Yukikiyo Kawakami, Hiromitsu Takizawa, Kazuya Kondo and Akira Tangoku : 呼吸器外科からみた結核スクリーニング-T-SPOT検査は有用であるか-, 第36回日本呼吸器外科学会総会, May 2019.
243.	Mika Takashima, Hiroaki Toba, Koichiro Kenzaki, 鈴木恵美, Ryo Yamada, 松本大資, Naoya Kawakita, Toru Sawada, Mitsuhiro Tsuboi, Yukikiyo Kawakami, Mitsuteru Yoshida, Hiromitsu Takizawa, Kazuya Kondo and Akira Tangoku : 胸腔内洗浄細胞診陽性Ⅰ期肺癌に対する術後化学療法の可能性, 第36回日本呼吸器外科学会総会, May 2019.
244.	Toru Sawada, Kazuya Kondo, Naoko Matsui, 鈴木恵美, Ryo Yamada, Mika Takashima, Daisuke Matsumoto, Naoya Kawakita, Mitsuhiro Tsuboi, Hiroaki Toba, Mitsuteru Yoshida, Yukikiyo Kawakami, Hiromitsu Takizawa and Akira Tangoku : 重症筋無力症に対する拡大胸腺摘出術の有効性について, 第36回日本呼吸器外科学会総会, May 2019.
245.	Hiroaki Toba, Ryo Yamada, Mika Takashima, Daisuke Matsumoto, Toru Sawada, Naoya Kawakita, Mitsuhiro Tsuboi, Yukikiyo Kawakami, Mitsuteru Yoshida, Hiromitsu Takizawa, Kazuya Kondo and Akira Tangoku : 小型末梢肺病変に対する気管支鏡下コイルマーキングを用いたimage-guided VATS, 第36回日本呼吸器外科学会総会, May 2019.
246.	Naoya Kawakita, Hiroaki Toba, 鈴木恵美, Ryo Yamada, Mika Takashima, Daisuke Matsumoto, Toru Sawada, Mitsuhiro Tsuboi, Yukikiyo Kawakami, Mitsuteru Yoshida, Hiromitsu Takizawa, Kazuya Kondo and Akira Tangoku : 遷延性肺瘻の予測スコアは治療介入時期決定に有用である-Prospective study-, 第36回日本呼吸器外科学会総会, May 2019.
247.	Mitsuhiro Tsuboi, Mika Takashima, Daisuke Matsumoto, Naoya Kawakita, Toru Sawada, Hiroaki Toba, Yukikiyo Kawakami, Mitsuteru Yoshida, Hiromitsu Takizawa, Kazuya Kondo and Akira Tangoku : 転移性肺腫瘍に対する解剖学的肺切除の役割, 第36回日本呼吸器外科学会総会, May 2019.
248.	Daisuke Matsumoto, Hiroaki Toba, 鈴木恵美, Ryo Yamada, 高嶋美佳, Naoya Kawakita, Toru Sawada, Mitsuhiro Tsuboi, Yukikiyo Kawakami, Mitsuteru Yoshida, Hiromitsu Takizawa, Kazuya Kondo and Akira Tangoku : 腎細胞癌肺転移症例に対する集学的治療としての手術療法の意義, 第36回日本呼吸器外科学会総会, May 2019.
249.	Mitsuteru Yoshida, Kazuya Kondo, 湯浅将生, 池光大貴, Toru Sawada, 鈴木恵美, Ryo Yamada, Mika Takashima, Daisuke Matsumoto, Naoya Kawakita, Mitsuhiro Tsuboi, Hiroaki Toba, Yukikiyo Kawakami, Hiromitsu Takizawa and Akira Tangoku : 残存脂肪組織量から拡大胸腺摘出術を考える, 第36回日本呼吸器外科学会総会, May 2019.
250.	Takahiro Yoshida, Takeshi Nishino, Seiya Inoue, Masakazu Goto, Mitsuhiro Tsuboi, Mariko Aoyama, Hiroaki Toba, Mitsuteru Yoshida, Hiromitsu Takizawa, Akira Tangoku, Hiro-omi Kanayama and Yoshihiro Tsuruo : 《CST推進委員会・厚生労働班会議合同企画》未固定カダバーによる教育と研究徳島大学の取り組み, 第119回日本外科学会定期学術集会, Apr. 2019.
251.	Naoya Kawakita, Hiroaki Toba, 鈴木恵美, 山田亮, Mika Takashima, Daisuke Matsumoto, Toru Sawada, Mitsuhiro Tsuboi, Yukikiyo Kawakami, Mitsuteru Yoshida, Hiromitsu Takizawa, Kazuya Kondo and Akira Tangoku : 《ワークショップ》遷延性肺瘻の予測スコアは治療介入時期決定に有用である, 第119回日本外科学会定期学術集会, Apr. 2019.
252.	Mitsuhiro Tsuboi, Naoya Kawakita, Hiromitsu Takizawa, 鈴木恵美, 山田亮, Mika Takashima, Daisuke Matsumoto, Toru Sawada, Hiroaki Toba, Yukikiyo Kawakami, Mitsuteru Yoshida, Kazuya Kondo and Akira Tangoku : 《ミニシンポジウム》肺野末梢病変に対するCone-beam CTを用いた極細径気管支鏡下肺生検, 第59回日本呼吸器学会学術講演会, Apr. 2019.
253.	Hiroaki Toba, 六田暉朗, Koichiro Kenzaki, 高嶋美佳, 松本大資, Naoya Kawakita, Toru Sawada, Mitsuhiro Tsuboi, Yukikiyo Kawakami, Mitsuteru Yoshida, Hiromitsu Takizawa, Kazuya Kondo and Akira Tangoku : 気管支鏡検査用新型局所麻酔薬噴霧カテーテルスプレーの使用経験, 第27回日本呼吸器内視鏡学会中国四国支部会, Dec. 2018.
254.	Daisuke Matsumoto, Hiromitsu Takizawa, 鈴木恵美, 山田亮, Mika Takashima, Naoya Kawakita, Toru Sawada, Mitsuhiro Tsuboi, Hiroaki Toba, Yukikiyo Kawakami, Mitsuteru Yoshida, Kazuya Kondo and Akira Tangoku : 再発胸腺上皮性腫瘍に対する手術療法の意義, 第59回日本肺癌学会総会, Nov. 2018.
255.	Mitsuteru Yoshida, Hirohisa Ogawa, 湯浅康弘, Hiromitsu Takizawa, 鈴木恵美, 山田亮, Mika Takashima, Daisuke Matsumoto, Toru Sawada, Naoya Kawakita, Mitsuhiro Tsuboi, Hiroaki Toba, Yukikiyo Kawakami, Kazuya Kondo and Akira Tangoku : CTでの充実径計測は妥当か，上皮内癌，微小浸潤癌におけるVINCENT3D解析と病理像の比較, 第59回日本肺癌学会総会, Nov. 2018.
256.	Mitsuhiro Tsuboi, Kazuya Kondo, Mika Takashima, Daisuke Matsumoto, Naoya Kawakita, Toru Sawada, Hiroaki Toba, Yukikiyo Kawakami, Mitsuteru Yoshida, Hiromitsu Takizawa and Akira Tangoku : 《口演》腺癌におけるGAD1発現の臨床的意義, 第59回日本肺癌学会総会, Nov. 2018.
257.	副島志帆, ウシマンヌリアミナ, Kazuya Kondo, 岸渕麗奈, Mitsuhiro Tsuboi, Koichiro Kajiura, Yukikiyo Kawakami, Naoya Kawakita, Toru Sawada, Hiroaki Toba, Mitsuteru Yoshida, Hiromitsu Takizawa and Akira Tangoku : 《口演》胸腺上皮性腫瘍の悪性度とGAD1(glutamic acid decarboxylase1)遺伝子のDNAメチル化の関係, 第59回日本肺癌学会総会, Nov. 2018.
258.	Toru Sawada, Hiromitsu Takizawa, 鈴木恵美, 山田亮, Mika Takashima, Daisuke Matsumoto, Naoya Kawakita, Mitsuhiro Tsuboi, Hiroaki Toba, Mitsuteru Yoshida, Yukikiyo Kawakami, Kazuya Kondo and Akira Tangoku : 《口演》肺癌における胸膜浸潤診断の予測因子の検討, 第59回日本肺癌学会総会, Nov. 2018.
259.	Mika Takashima, Hiroaki Toba, 鈴木恵美, Daisuke Matsumoto, Naoya Kawakita, Toru Sawada, Mitsuhiro Tsuboi, Yukikiyo Kawakami, Mitsuteru Yoshida, Hiromitsu Takizawa, Kazuya Kondo and Akira Tangoku : 当科における胸腔内洗浄細胞診陽性症例での再発例の検討, 第80回日本臨床外科学会総会, Nov. 2018.
260.	鈴木恵美, Mika Takashima, Hiroaki Toba, Takahiro Yoshida, Daisuke Matsumoto, Masami Morimoto, Naoya Kawakita, Toru Sawada, Mitsuhiro Tsuboi, Hirokazu Takechi, Yukikiyo Kawakami, Mitsuteru Yoshida, Hiromitsu Takizawa, Kazuya Kondo and Akira Tangoku : 放射線皮膚潰瘍・胸骨骨髄炎に対し広汎骨性胸郭切除を行った乳癌再発の1例, 第80回日本臨床外科学会総会, Nov. 2018.
261.	Mitsuhiro Tsuboi, Mariko Aoyama, Hiromitsu Takizawa, Takahiro Yoshida, Mitsuteru Yoshida and Akira Tangoku : 《シンポジウム》内視鏡下甲状腺手術におけるCadaver training, 第80回日本臨床外科学会総会, Nov. 2018.
262.	Toru Sawada, Hiromitsu Takizawa, Naoya Kawakita, Mitsuhiro Tsuboi, Hiroaki Toba, Mitsuteru Yoshida, Yukikiyo Kawakami, Kazuya Kondo and Akira Tangoku : 《一般口演》肺癌胸膜浸潤の術中評価における我々の取り組み, 第39回日本レーザー医学会総会, Nov. 2018.
263.	青山万理子, Hiromitsu Takizawa, Mitsuhiro Tsuboi and Akira Tangoku : 《口演》FDG-PET/CTで発見された甲状腺異常集積症例の検討, 第51回日本甲状腺外科学会学術集会, Oct. 2018.
264.	Mitsuhiro Tsuboi, 青山万理子, Hiromitsu Takizawa and Akira Tangoku : 《口演》内視鏡下甲状腺手術の最適化を目指して, 第51回日本甲状腺外科学会学術集会, Oct. 2018.
265.	高嶋美佳, Mitsuteru Yoshida, Kazuya Kondo, Mitsuhiro Tsuboi, Naoya Kawakita, Toru Sawada, 鈴木恵美, 山田亮, 松本大資, Hiroaki Toba, Yukikiyo Kawakami, Hiromitsu Takizawa and Akira Tangoku : 剣状突起下アプローチ拡大胸腺摘出術の当院における導入の経験, 第93回中国四国外科学会総会・第23回中国四国内視鏡外科研究会, Sep. 2018.
266.	多幡有莉乃, Hirokazu Ogino, Atsuro Saijo, Hiroyuki Kozai, Mayo Kondou, Yoshimi Bando, 松本大資, Hisatsugu Goto, Hiromitsu Takizawa and Yasuhiko Nishioka : 悪性胸水を契機に診断された放射線誘発血管肉腫の1例, 第59回日本呼吸器学会中国・四国地方会, Jul. 2018.
267.	鈴木恵美, Mitsuteru Yoshida, Kazuya Kondo, 山田亮, Toru Sawada, Naoya Kawakita, Mitsuhiro Tsuboi, Hiroaki Toba, Yukikiyo Kawakami, Hiromitsu Takizawa and Akira Tangoku : 前縦隔に発生した粘液線維肉腫の一切除例, 第59回日本呼吸器学会中国・四国地方会/第57回日本肺癌学会中国・四国支部学術集会, Jul. 2018.
268.	山田亮, Mitsuteru Yoshida, Naoya Kawakita, 鈴木恵美, 高嶋美佳, 松本大資, Toru Sawada, Mitsuhiro Tsuboi, Hiroaki Toba, Yukikiyo Kawakami, Hiromitsu Takizawa, Kazuya Kondo and Akira Tangoku : 肺癌との鑑別に苦慮した，気管内過誤腫による閉塞性肺炎の一切除例, 第59回日本呼吸器学会中国・四国地方会/第57回日本肺癌学会中国・四国支部学術集会, Jul. 2018.
269.	青山万理子, Hiromitsu Takizawa, Mitsuhiro Tsuboi and Akira Tangoku : 《一般演題(口演)》縦隔内副甲状腺腺腫に対するアプローチの工夫-気縦隔法併用縦隔鏡手術について-, 第30回日本内分泌外科学会総会, Jun. 2018.
270.	Naoya Kawakita, Hiromitsu Takizawa, Takahiro Yoshida, Toru Sawada, Seiya Inoue, Masakazu Goto, Takeshi Nishino, Mitsuhiro Tsuboi, Hiroaki Toba, Yukikiyo Kawakami, Mitsuteru Yoshida, Kazuya Kondo and Akira Tangoku : 《Case Presentation Award》有茎大網弁被覆により有瘻性膿胸を回避できた右上葉管状肺葉切除の1例, 第61回関西胸部外科学会学術集会, Jun. 2018.
271.	Hiroaki Toba, Toru Sawada, Naoya Kawakita, Mitsuhiro Tsuboi, Yukikiyo Kawakami, Mitsuteru Yoshida, Hiromitsu Takizawa, Takahiro Yoshida and Akira Tangoku : 《一般口演》肺癌術後再発例の地域連携から看取りについて-良い連携ができた1例から考える-, 第43回日本外科系連合学会学術集会, Jun. 2018.
272.	Naoya Kawakita, Hiromitsu Takizawa, Toru Sawada, Mitsuhiro Tsuboi, Hiroaki Toba, Yukikiyo Kawakami, Mitsuteru Yoshida, Kazuya Kondo and Akira Tangoku : Cone-beam CT併用による極細径気管支鏡下肺生検の初期導入経験, 第41回日本呼吸器内視鏡学会学術集会, May 2018.
273.	Mitsuhiro Tsuboi, Hiromitsu Takizawa, Naoya Kawakita, Toru Sawada, Hiroaki Toba, Yukikiyo Kawakami, Mitsuteru Yoshida, Kazuya Kondo and Akira Tangoku : Cone-beam CTガイド下肺野末梢病変の経気管支鏡診断においてCBCT signは重要である, 第41回日本呼吸器内視鏡学会学術集会, May 2018.
274.	Toru Sawada, Mitsuteru Yoshida, Naoya Kawakita, Mitsuhiro Tsuboi, Hiroaki Toba, Yukikiyo Kawakami, Hiromitsu Takizawa, Kazuya Kondo and Akira Tangoku : 《Oralセッション》気管支鏡の故障をいかに防ぐか∼我々の知るべきこと∼, 第41回日本呼吸器内視鏡学会学術集会, May 2018.
275.	Mitsuteru Yoshida, Momoyo Azuma, Toru Sawada, Naoya Kawakita, Mitsuhiro Tsuboi, Hiroaki Toba, Yukikiyo Kawakami, Hiromitsu Takizawa, Kazuya Kondo and Akira Tangoku : 《Oralセッション》結核スクリーニングにおけるT-SPOT測定-気管支鏡検査，胸腔鏡生検の役割-, 第41回日本呼吸器内視鏡学会学術集会, May 2018.
276.	Hiroaki Toba, 六田暉朗, Toru Sawada, Naoya Kawakita, Mitsuhiro Tsuboi, Yukikiyo Kawakami, Mitsuteru Yoshida, Hiromitsu Takizawa, Kazuya Kondo and Akira Tangoku : 《Oralセッション》気管支鏡検査用新型局所麻酔薬噴霧カテーテルスプレーの使用経験, 第41回日本呼吸器内視鏡学会学術集会, May 2018.
277.	Hiroaki Toba, Toru Sawada, Naoya Kawakita, Mitsuhiro Tsuboi, Yukikiyo Kawakami, Mitsuteru Yoshida, Hiromitsu Takizawa, Kazuya Kondo and Akira Tangoku : 《Videoセッション》Hybrid手術室で行う小型末梢肺病変に対するCone-beam CTガイド下気管支鏡下コイルマーキング, 第41回日本呼吸器内視鏡学会学術集会, May 2018.
278.	Hiromitsu Takizawa, Naoya Kawakita, Mitsuteru Yoshida, Seiya Inoue, Masakazu Goto, Takeshi Nishino, Takahiro Yoshida, Toru Sawada, Mitsuhiro Tsuboi, Hiroaki Toba, Yukikiyo Kawakami, Kazuya Kondo and Akira Tangoku : 《シンポジウム》未固体遺体による高難度手術の術前シミュレーション, 第41回日本呼吸器内視鏡学会学術集会, May 2018.
279.	Hiromitsu Takizawa, Naoya Kawakita, Toru Sawada, Takeshi Nishino, Mitsuhiro Tsuboi, Hiroaki Toba, Yukikiyo Kawakami, Mitsuteru Yoshida, Kazuya Kondo and Akira Tangoku : 《一般示説》微小浸潤性腺癌を術前診断するのは困難である, 第35回日本呼吸器外科学会総会・学術集会, May 2018.
280.	Toru Sawada, Kazuya Kondo, Naoya Kawakita, Mitsuhiro Tsuboi, Hiroaki Toba, Yukikiyo Kawakami, Mitsuteru Yoshida, Hiromitsu Takizawa and Akira Tangoku : 《一般示説》重症筋無力症の拡大胸腺摘出術の長期効果と周術期管理, 第35回日本呼吸器外科学会総会・学術集会, May 2018.
281.	Mitsuhiro Tsuboi, Kazuya Kondo, Naoya Kawakita, Toru Sawada, Hiroaki Toba, Yukikiyo Kawakami, Mitsuteru Yoshida, Hiromitsu Takizawa and Akira Tangoku : 《一般口演》根治手術後の胸腺癌の再発病変に対する治療, 第35回日本呼吸器外科学会総会・学術集会, May 2018.
282.	Yukikiyo Kawakami, Naoya Kawakita, Toru Sawada, Mitsuhiro Tsuboi, Hiroaki Toba, Hiromitsu Takizawa, Mitsuteru Yoshida, Kazuya Kondo and Akira Tangoku : 《一般口演》肺葉切除後の肺静脈断端血栓とそれに起因する合併症, 第35回日本呼吸器外科学会総会・学術集会, May 2018.
283.	Kazuya Kondo, 副島志帆, ウシマンヌリアミナ, 岸渕麗奈, Mitsuhiro Tsuboi, Koichiro Kajiura, Yukikiyo Kawakami, Naoya Kawakita, Toru Sawada, Hiroaki Toba, Mitsuteru Yoshida, Hiromitsu Takizawa and Akira Tangoku : 《要望演題》胸腺上皮性腫瘍におけるGAD1(glutamic acid decarboxylase1)遺伝子のDNAメチル化とmRNA，蛋白発現, 第35回日本呼吸器外科学会総会・学術集会, May 2018.
284.	Naoya Kawakita, Hiroaki Toba, Toru Sawada, Mitsuhiro Tsuboi, Yukikiyo Kawakami, Mitsuteru Yoshida, Hiromitsu Takizawa, Kazuya Kondo and Akira Tangoku : 《要望演題》遷延性肺瘻の予測因子に基づいた治療方針決定の可能性, 第35回日本呼吸器外科学会総会・学術集会, May 2018.
285.	Mitsuteru Yoshida, Hiromitsu Takizawa, Toru Sawada, Naoya Kawakita, Mitsuhiro Tsuboi, Hiroaki Toba, Yukikiyo Kawakami, Kazuya Kondo and Akira Tangoku : 《要望演題》微小浸潤癌，上皮内癌の組織像と定量的CT画像解析の検討-SYNAPSE VINCENTを用いて-, 第35回日本呼吸器外科学会総会・学術集会, May 2018.
286.	Hiroaki Toba, Toru Sawada, Naoya Kawakita, Mitsuhiro Tsuboi, Yukikiyo Kawakami, Mitsuteru Yoshida, Hiromitsu Takizawa, Kazuya Kondo and Akira Tangoku : 《シンポジウム》Hybrid手術室で行う小型末梢肺病変に対するCone-beamCTガイド下気管支鏡下コイルマーキング, 第35回日本呼吸器外科学会総会・学術集会, May 2018.
287.	Makoto Tobiume, Hirokazu Ogino, Afroj Tania, Hisatsugu Goto, Hiroshi Nokihara, Mitsuteru Yoshida, Yukikiyo Kawakami, Hiromitsu Takizawa, Hirohisa Ogawa, Koichi Tsuneyama and Yasuhiko Nishioka : 上皮間葉転換 (EMT)が肺多形癌の悪性化に寄与する可能性についての検討., 第58回日本呼吸器学会学術講演会, Apr. 2018.
288.	Hiroaki Toba, Toru Sawada, Naoya Kawakita, Mitsuhiro Tsuboi, Yukikiyo Kawakami, Mitsuteru Yoshida, Hiromitsu Takizawa, Kazuya Kondo and Akira Tangoku : 小型末梢肺病変に対するCone-beam CT併用気管支鏡下コイルマーキング-Hybrid手術室で全身麻酔下にすべてできる-, 第118回日本外科学会定期学術集会, Apr. 2018.
289.	Hiromitsu Takizawa, Naoya Kawakita, Toru Sawada, Mitsuhiro Tsuboi, Hiroaki Toba, Mitsuteru Yoshida, Yukikiyo Kawakami, Kazuya Kondo and Akira Tangoku : 肺切除が有効である大腸癌肺転移症例の臨床病理学的背景, 第118回日本外科学会定期学術集会, Apr. 2018.
290.	青山万理子, Mitsuteru Yoshida, 行重佐和香, Toru Sawada, Naoya Kawakita, Mitsuhiro Tsuboi, Hiroaki Toba, Yukikiyo Kawakami, Hiromitsu Takizawa, Kazuya Kondo and Akira Tangoku : 後縦隔ミュラー管嚢胞の1例, 第79回日本臨床外科学会総会, Nov. 2017.
291.	Toru Sawada, Hiromitsu Takizawa, Naoya Kawakita, Mitsuhiro Tsuboi, Hiroaki Toba, Mitsuteru Yoshida, Yukikiyo Kawakami, Kazuya Kondo and Akira Tangoku : 肝細胞癌肺転移に対してICG蛍光観察下に胸腔鏡下肺部分切除を行った1例, 第79回日本臨床外科学会総会, Nov. 2017.
292.	行重佐和香, Yukikiyo Kawakami, Toru Sawada, Naoya Kawakita, Mitsuhiro Tsuboi, Hiroaki Toba, Mitsuteru Yoshida, Hiromitsu Takizawa, Kazuya Kondo and Akira Tangoku : Minute pulmonary meningothelial like nodulesの3例, 第79回日本臨床外科学会総会, Nov. 2017.
293.	Naoya Kawakita, Ali Eman, Hiromitsu Takizawa, Mitsuhiro Tsuboi, Hiroaki Toba, Yukikiyo Kawakami, Mitsuteru Yoshida, Akira Tangoku and Kazuya Kondo : 《渡辺洋一記念奨励賞選考対象演題》(呼吸器内視鏡)コンビームCTによる気管支鏡生検の検査精度向上, 第26回日本呼吸器内視鏡学会中国四国支部会, Oct. 2017.
294.	Koichiro Kajiura, Kazuya Kondo, Toru Sawada, Naoya Kawakita, Mitsuhiro Tsuboi, Hiroaki Toba, Mitsuteru Yoshida, Hiromitsu Takizawa and Akira Tangoku : 胸腺上皮性腫瘍におけるCDH3のDNAメチル化, 第58回日本肺癌学会学術集会, Oct. 2017.
295.	松本充鈴, 田岡志津佳, Takae Bando, Kazuya Kondo, Koichiro Kajiura, Hiromitsu Takizawa, Yoshie Imai, Aki Takahashi and Chiemi Onishi : 治療過程にある再発・転移肺がん患者の心理的適応, 第58回日本肺癌学会学術集会, Vol.57, No.5, 437, Oct. 2017.
296.	Yukikiyo Kawakami, Naoya Kawakita, Toru Sawada, Mitsuhiro Tsuboi, Hiroaki Toba, Hiromitsu Takizawa, Mitsuteru Yoshida, Kazuya Kondo and Akira Tangoku : 肺癌術前のリンパ節転移評価におけるPET-CT検査の診断精度, 第70回日本胸部外科学会定期学術集会, Sep. 2017.
297.	Koichiro Kajiura, Kazuya Kondo, Toru Sawada, Naoya Kawakita, Mitsuhiro Tsuboi, Hiroaki Toba, Mitsuteru Yoshida, Hiromitsu Takizawa and Akira Tangoku : 《一般口演》凝固壊死を伴う胸腺上皮性腫瘍の検討, 第70回日本胸部外科学会定期学術集会, Sep. 2017.
298.	山口佑樹, Sumiko Yoshida, 細井美希, 山上紘規, 原倫世, 桝田志保, Kiyoe Kurahashi, Akio Kuroda, 明比祐子, Itsuro Endo, Ken-ichi Aihara, Munehide Matsuhisa, Makoto Funaki, Seiji Fukumoto and Hiromitsu Takizawa : 当院での免疫チェックポインント阻害薬による内分泌異常の発生と有害事象対策, 第255回徳島医学会学術集会(平成29年度夏期), Aug. 2017.
299.	藤本啓介, Naoya Kawakita, Koichiro Kajiura, 西岡康平, 宮本直輝, Toru Sawada, Mitsuhiro Tsuboi, Hiroaki Toba, Mitsuteru Yoshida, Yukikiyo Kawakami, Hiromitsu Takizawa, Kazuya Kondo and Akira Tangoku : 肺切除術直後に急性心筋梗塞を発症した1例, 第42回日本外科系連合学会学術集会, Jun. 2017.
300.	Naoya Kawakita, 藤本啓介, 西岡康平, 宮本直輝, Toru Sawada, Mitsuhiro Tsuboi, Koichiro Kajiura, Hiroaki Toba, Yukikiyo Kawakami, Mitsuteru Yoshida, Hiromitsu Takizawa, Kazuya Kondo, Shoji Sakiyama, 広瀬敏幸 and Akira Tangoku : BEP療法中に発症した間質性肺炎治療後に手術を施行した2例, 第42回日本外科系連合学会学術集会, Jun. 2017.
301.	Mitsuteru Yoshida, Hiromitsu Takizawa, Toru Sawada, Naoya Kawakita, Mitsuhiro Tsuboi, Koichiro Kajiura, Hiroaki Toba, Yukikiyo Kawakami, Kazuya Kondo, Akira Tangoku, Takashi Iwata, Masashi Akaike, Hiro-omi Kanayama, Kousaku Higashino and Yoshihiro Tsuruo : 鏡視下手術時代の教育の開発未固定遺体を用いた胸腔鏡手術トレーニングの経験, 第42回日本外科系連合学会学術集会, Jun. 2017.
302.	Toru Sawada, Hiromitsu Takizawa, 宮本直輝, Naoya Kawakita, Mitsuhiro Tsuboi, Koichiro Kajiura, Hiroaki Toba, Mitsuteru Yoshida, Yukikiyo Kawakami, Kazuya Kondo and Akira Tangoku : 胸腔鏡下手術における3D内視鏡システムの有用性について, 第42回日本外科系連合学会学術集会, Jun. 2017.
303.	Mitsuhiro Tsuboi, Hiromitsu Takizawa, 青山万理子, Seiya Inoue, Naoya Kawakita, Toru Sawada, Takeshi Nishino, Misako Nakagawa, Kazumasa Okumura, Hirokazu Takechi, Hiroaki Toba, Takahiro Yoshida, Yukikiyo Kawakami, Mitsuteru Yoshida and Akira Tangoku : 《一般口演》総頚動脈再建を行った甲状腺乳頭癌の1例, 第42回日本外科系連合学会学術集会, Jun. 2017.
304.	青山万理子, Mitsuhiro Tsuboi, Naoya Kawakita, Hiromitsu Takizawa, Akira Tangoku, Kousaku Higashino and Yoshihiro Tsuruo : 《一般口演》当科における未固定遺体を用いた手術トレーニングと内視鏡下甲状腺手術導入の取り組み, 第42回日本外科系連合学会学術集会, Jun. 2017.
305.	Takeshi Nishino, Takahiro Yoshida, Seiya Inoue, 青山万理子, Toru Sawada, Naoya Kawakita, Mitsuhiro Tsuboi, Hiroaki Toba, Hiromitsu Takizawa and Akira Tangoku : 《ワークショップ》胸部外科手術における合併症予防のためのチームのちから-医科歯科連携の成果-, 第42回日本外科系連合学会学術集会, Jun. 2017.
306.	Hiroaki Toba, Toru Sawada, Naoya Kawakita, Mitsuhiro Tsuboi, Koichiro Kajiura, Yukikiyo Kawakami, Mitsuteru Yoshida, Hiromitsu Takizawa, Kazuya Kondo and Akira Tangoku : 《ワークショップ》当院における肺がん術後連携クリニカルパス-連携不良例から今後の方向性を考える-, 第42回日本外科系連合学会学術集会, Jun. 2017.
307.	宮本直輝, Mitsuteru Yoshida, 藤本啓介, 西岡康平, 青山万理子, Toru Sawada, Naoya Kawakita, Mitsuhiro Tsuboi, Koichiro Kajiura, Hiroaki Toba, Yukikiyo Kawakami, Hiromitsu Takizawa, Kazuya Kondo and Akira Tangoku : DynaCTの気管支鏡生検における可能性, 第40回日本呼吸器内視鏡学会学術集会, Jun. 2017.
308.	Koichiro Kajiura, Hiromitsu Takizawa, Mitsuhiro Tsuboi, Toru Sawada, Naoya Kawakita, Hiroaki Toba, Yukikiyo Kawakami, Mitsuteru Yoshida, Kazuya Kondo and Akira Tangoku : 有瘻性膿胸に対するEWSを用いた気管支充填術, 第40回日本呼吸器内視鏡学会学術集会, Jun. 2017.
309.	Mitsuteru Yoshida, 宮本直輝, Toru Sawada, Naoya Kawakita, Mitsuhiro Tsuboi, Koichiro Kajiura, Hiroaki Toba, Yukikiyo Kawakami, Hiromitsu Takizawa, Kazuya Kondo and Akira Tangoku : 呼吸器外科手術における血管の破格症例, 第26回日本癌病態治療研究会, Jun. 2017.
310.	Yukikiyo Kawakami, Naoya Kawakita, Toru Sawada, Mitsuhiro Tsuboi, Hiroaki Toba, Hiromitsu Takizawa, Mitsuteru Yoshida, Kazuya Kondo and Akira Tangoku : 肺癌術後再発の長期生存例の検討, 第26回日本癌病態治療研究会, Jun. 2017.
311.	Koichiro Kajiura, Kazuya Kondo, Toru Sawada, Naoya Kawakita, Mitsuhiro Tsuboi, Hiroaki Toba, Mitsuteru Yoshida, Hiromitsu Takizawa and Akira Tangoku : 縦隔嚢胞性疾患における嚢胞内成分の鑑別指標となる画像診断, 第34回日本呼吸器外科学会総会, May 2017.
312.	宮本直輝, Mitsuteru Yoshida, 藤本啓介, 西岡康平, 青山万理子, Toru Sawada, Naoya Kawakita, Mitsuhiro Tsuboi, Koichiro Kajiura, Hiroaki Toba, Yukikiyo Kawakami, Hiromitsu Takizawa, Kazuya Kondo and Akira Tangoku : ハイブリッド手術室を利用したVATSの経験, 第34回日本呼吸器外科学会総会, May 2017.
313.	Toru Sawada, Mitsuhiro Tsuboi, 宮本直輝, Naoya Kawakita, Koichiro Kajiura, Hiroaki Toba, Yukikiyo Kawakami, Mitsuteru Yoshida, Hiromitsu Takizawa, Kazuya Kondo and Akira Tangoku : Trimodality theraphyにおける治療前後のSUVmaxと治療効果の関連性の検討, 第34回日本呼吸器外科学会総会, May 2017.
314.	Mitsuteru Yoshida, Kazuya Kondo, Koichiro Kajiura, 宮本直輝, Toru Sawada, Naoya Kawakita, Mitsuhiro Tsuboi, Hiroaki Toba, Yukikiyo Kawakami, Hiromitsu Takizawa and Akira Tangoku : 《一般口演》胸腺腫における石灰化は意義を持つのか, 第34回日本呼吸器外科学会総会, May 2017.
315.	Yukikiyo Kawakami, 青山万理子, Naoya Kawakita, Toru Sawada, Mitsuhiro Tsuboi, Koichiro Kajiura, Hiroaki Toba, Hiromitsu Takizawa, Mitsuteru Yoshida, Kazuya Kondo and Akira Tangoku : 《一般ビデオ》S6区域切除+フラップ気管支形成術を行った気管支内過誤腫の一例, 第34回日本呼吸器外科学会総会, May 2017.
316.	Hiroaki Toba, Toru Sawada, Naoya Kawakita, Mitsuhiro Tsuboi, Koichiro Kajiura, Yukikiyo Kawakami, Mitsuteru Yoshida, Hiromitsu Takizawa, Kazuya Kondo and Akira Tangoku : 《要望ビデオ》多発GGO病変に対して気管支鏡下コイルマーキングでS1側のマージンを担保した完全鏡視下右S2区域切除, 第34回日本呼吸器外科学会総会, May 2017.
317.	Mitsuhiro Tsuboi, Mitsuteru Yoshida, Naoya Kawakita, Koichiro Kajiura, Toru Sawada, Hiroaki Toba, Yukikiyo Kawakami, Hiromitsu Takizawa, Kazuya Kondo, Akira Tangoku and 須田隆 : 《要望演題》当科における剣状突起下切開単孔式胸腺摘出導入の取り組み-未固定遺体を用いた手術トレーニングについて-, 第34回日本呼吸器外科学会総会, May 2017.
318.	Naoya Kawakita, Hiroaki Toba, 広瀬敏幸, 松本大資, Toru Sawada, Mitsuhiro Tsuboi, Koichiro Kajiura, Yasushi Nakagawa, Yukikiyo Kawakami, Mitsuteru Yoshida, Hiromitsu Takizawa, Kazuya Kondo and Akira Tangoku : 《シンポジウム》pStageⅠ肺腺癌の治療戦略-簡便な3因子を用いた予後の層別化と術後補助療法の可能性-, 第34回日本呼吸器外科学会総会, May 2017.
319.	Mitsuteru Yoshida, Hiromitsu Takizawa, Takahiro Yoshida, Mitsuhiro Tsuboi, Naoya Kawakita, Toru Sawada, Koichiro Kajiura, Hiroaki Toba, Yukikiyo Kawakami, Kazuya Kondo, Akira Tangoku, Takashi Iwata, Masashi Akaike, Hiro-omi Kanayama, 東野耕作 and Yoshihiro Tsuruo : 《考える外科学》未固定遺体とのシミュレーションを用いた新たな実践型内視鏡下低侵襲手術トレーニングプログラムの構築, 第117回日本外科学会定期学術集会, Apr. 2017.
320.	澤田徹, Hiromitsu Takizawa, 宮本直輝, Naoya Kawakita, Mitsuhiro Tsuboi, Koichiro Kajiura, Hiroaki Toba, Mitsuteru Yoshida, Yukikiyo Kawakami, Kazuya Kondo and Akira Tangoku : 胸腔鏡下手術における3D内視鏡システムの有用性について, 第56回日本呼吸器学会中国・四国地方会/第25回日本呼吸器内視鏡学会中国四国支部会, Dec. 2016.
321.	Koichiro Kajiura, Kazuya Kondo, Takanori Miyoshi, 松本大資, Yasushi Nakagawa, 石倉久嗣, 松岡永, Koichiro Kenzaki, 澤田徹, Naoya Kawakita, Mitsuhiro Tsuboi, Hiroaki Toba, Yukikiyo Kawakami, Mitsuteru Yoshida, Hiromitsu Takizawa and Akira Tangoku : 胸膜播種を伴う胸腺上皮性腫瘍の検討, 第57回日本肺癌学会総会, Dec. 2016.
322.	宮本直輝, Mitsuteru Yoshida, 澤田徹, Naoya Kawakita, Mitsuhiro Tsuboi, Koichiro Kajiura, Hiroaki Toba, Yukikiyo Kawakami, Hiromitsu Takizawa, Shoji Sakiyama, Kazuya Kondo and Akira Tangoku : 右上葉区域肺静脈(V2)の分岐走行異常の検討, 第57回日本肺癌学会総会, Dec. 2016.
323.	澤田徹, Hiroaki Toba, 宮本直輝, Naoya Kawakita, Mitsuhiro Tsuboi, Koichiro Kajiura, Yukikiyo Kawakami, Mitsuteru Yoshida, Hiromitsu Takizawa, Kazuya Kondo and Akira Tangoku : 胸腺上皮性腫瘍におけるFDG-PET/CTの有用性∼SUVmax値はRFSの予測因子になるか?, 第57回日本肺癌学会総会, Dec. 2016.
324.	Naoya Kawakita, Hiroaki Toba, 澤田徹, Mitsuhiro Tsuboi, Koichiro Kajiura, Yukikiyo Kawakami, Mitsuteru Yoshida, Hiromitsu Takizawa, Kazuya Kondo and Akira Tangoku : 《口演》根治切除を行ったpStageⅠ肺腺癌の予後因子による層別化, 第57回日本肺癌学会総会, Dec. 2016.
325.	宮本直輝, Koichiro Kajiura, 藤本啓介, 西岡康平, 青山万理子, 澤田徹, Naoya Kawakita, Mitsuhiro Tsuboi, Hiroaki Toba, Yukikiyo Kawakami, Mitsuteru Yoshida, Hiromitsu Takizawa, Kazuya Kondo and Akira Tangoku : 同一病変内に放線菌症とAdenocarcinomaを併発した一例, 第78回日本臨床外科学会総会, Nov. 2016.
326.	Koichiro Kajiura, Hiromitsu Takizawa, 宮本直輝, 澤田徹, Naoya Kawakita, Mitsuhiro Tsuboi, Hiroaki Toba, Yukikiyo Kawakami, Mitsuteru Yoshida, Kazuya Kondo and Akira Tangoku : Thopaz®によるドレーン管理中に起こった右肺全摘術後の皮下気腫の1例, 第78回日本臨床外科学会総会, Nov. 2016.
327.	西岡康平, Hiroaki Toba, 藤本啓介, 宮本直輝, Naoya Kawakita, 澤田徹, Mitsuhiro Tsuboi, Koichiro Kajiura, Yukikiyo Kawakami, Mitsuteru Yoshida, Hiromitsu Takizawa, Kazuya Kondo and Akira Tangoku : 再生不良性貧血を合併した胸腺腫に対して，術前大量ステロイド療法後に手術を施行し，pCRが得られた1例, 第78回日本臨床外科学会総会, Nov. 2016.
328.	Naoya Kawakita, Hiromitsu Takizawa, Koichiro Kajiura, 藤本啓介, 西岡康平, 宮本直輝, 澤田徹, Mitsuhiro Tsuboi, Hiroaki Toba, Yukikiyo Kawakami, Mitsuteru Yoshida, Kazuya Kondo and Akira Tangoku : 肝性胸水に対する胸腔鏡下横隔膜修復術の1例-術中気腹法およびICG蛍光法併用の試み-, 第78回日本臨床外科学会総会, Nov. 2016.
329.	Mitsuhiro Tsuboi, Hiromitsu Takizawa, 西岡康平, 藤本啓介, 宮本直輝, 青山万理子, 澤田徹, Naoya Kawakita and Akira Tangoku : レンバチニブ投与後に手術を行った局所進行甲状腺乳頭癌の1例, 第49回日本甲状腺外科学会学術集会, Oct. 2016.
330.	青山万理子, Hiromitsu Takizawa, Mitsuhiro Tsuboi and Akira Tangoku : 甲状腺全摘後にBasedow病を発症した甲状腺乳頭癌再発の1例, 第49回日本甲状腺外科学会学術集会, Oct. 2016.
331.	Koichiro Kajiura, Kazuya Kondo, 澤田徹, Mitsuhiro Tsuboi, Naoya Kawakita, Yukikiyo Kawakami, Hiroaki Toba, Mitsuteru Yoshida, Hiromitsu Takizawa and Akira Tangoku : 胸腺腫瘍におけるRASSF1のDNAメチル化の検討, 第69回日本胸部外科学会定期学術集会, Sep. 2016.
332.	Mitsuteru Yoshida, Kazuya Kondo, Yasushi Nakagawa, 澤田徹, Naoya Kawakita, Mitsuhiro Tsuboi, Koichiro Kajiura, Hiroaki Toba, Yukikiyo Kawakami, Hiromitsu Takizawa, Shoji Sakiyama and Akira Tangoku : 《一般口演》胸腺腫非合併重症筋無力症患者の術前3D画像評価-拡大胸腺摘出術後の予後予測は可能か-, 第69回日本胸部外科学会定期学術集会, Sep. 2016.
333.	Mitsuhiro Tsuboi, Hiromitsu Takizawa, Naoya Kawakita, 澤田徹, Takeshi Nishino, Koichiro Kajiura, Hiroaki Toba, Yukikiyo Kawakami, Mitsuteru Yoshida, Kazuya Kondo and Akira Tangoku : 《一般口演》疾患特性に応じた続発性気胸に対する治療戦略, 第69回日本胸部外科学会定期学術集会, Sep. 2016.
334.	Hiromitsu Takizawa : 《パネルディスカッション》CTリンパ管造影所見による至適リンパ節郭清範囲の検討, 第69回日本胸部外科学会定期学術集会, Sep. 2016.
335.	藤本啓介, Mitsuhiro Tsuboi, 西岡康平, 宮本直輝, 青山万理子, Hiromitsu Takizawa and Akira Tangoku : 低分化成分を伴った甲状腺濾胞癌未分化転化の1例, 第91回中国四国外科学会総会・第21回中国四国内視鏡外科研究会, Sep. 2016.
336.	宮本直輝, Naoya Kawakita, 藤本啓介, 西岡康平, 青山万理子, 澤田徹, Mitsuhiro Tsuboi, Koichiro Kajiura, Hiroaki Toba, Yukikiyo Kawakami, Mitsuteru Yoshida, Hiromitsu Takizawa, Kazuya Kondo, Shoji Sakiyama and Akira Tangoku : 《後期研修医セッション:呼吸器1》FDG-PET/CT陽性を呈した肺原発benign perivascular epithelioid cell tumorの一例, 第91回中国四国外科学会総会・第21回中国四国内視鏡外科研究会, Sep. 2016.
337.	Mayo Kondoh, Toshifumi Tezuka, Hiroto Yoneda, Yuko Toyoda, Hisatsugu Goto, Jun Kishi, Masahiko Azuma, Masaki Hanibuchi, Taichi Murakami, Toshio Doi, Naoya Kawakita, Hiromitsu Takizawa and Yasuhiko Nishioka : 腹腔シンチグラフィにより診断し横隔膜縫合閉鎖術を行った横隔膜交通症の1例, 第55 回日本呼吸器学会中国・四国地方会, Jul. 2016.
338.	Koichiro Kajiura, Hiromitsu Takizawa, Naoya Kawakita, Mitsuhiro Tsuboi, Hiroaki Toba, Mitsuteru Yoshida, Yukikiyo Kawakami, Shoji Sakiyama, Kazuya Kondo and Akira Tangoku : EWSによる気管支充填術の有用性評価, 第39回日本呼吸器内視鏡学会学術集会, Jun. 2016.
339.	松本大資, Hiromitsu Takizawa, 乾友浩, 髙杉遥, Naoya Kawakita, Mitsuhiro Tsuboi, Koichiro Kajiura, Hiroaki Toba, Yukikiyo Kawakami, Mitsuteru Yoshida, Kazuya Kondo, Shoji Sakiyama and Akira Tangoku : 肺癌術後に気管支鏡的処置を要した症例の検討, 第39回日本呼吸器内視鏡学会学術集会, Jun. 2016.
340.	Naoya Kawakita, Hiroaki Toba, Shoji Sakiyama, 松本大資, Mitsuhiro Tsuboi, Koichiro Kajiura, Yukikiyo Kawakami, Mitsuteru Yoshida, Hiromitsu Takizawa, Kazuya Kondo and Akira Tangoku : 選択的肺葉ブロックが有用であった肺切除術の2例, 第39回日本呼吸器内視鏡学会学術集会, Jun. 2016.
341.	Mitsuhiro Tsuboi, 松本大資, Naoya Kawakita, Koichiro Kajiura, Hiroaki Toba, Yukikiyo Kawakami, Mitsuteru Yoshida, Hiromitsu Takizawa, Shoji Sakiyama, Kazuya Kondo and Akira Tangoku : 人工気胸を併用した胸腔鏡下胸腺部分切除の1例, 第39回日本呼吸器内視鏡学会学術集会, Jun. 2016.
342.	Hiroaki Toba, Shoji Sakiyama, 松本大資, Naoya Kawakita, Mitsuhiro Tsuboi, Koichiro Kajiura, Mitsuteru Yoshida, Yukikiyo Kawakami, Hiromitsu Takizawa, Kazuya Kondo and Akira Tangoku : 未確診肺結節のVATS切除における肺結核感染予防体制の構築, 第41回日本外科系連合学会学術集会, Jun. 2016.
343.	松本大資, Shoji Sakiyama, 乾友浩, 高杉遥, Naoya Kawakita, Takeshi Nishino, Mitsuhiro Tsuboi, Koichiro Kajiura, Hiroaki Toba, Yukikiyo Kawakami, Mitsuteru Yoshida, Hiromitsu Takizawa, Kazuya Kondo and Akira Tangoku : 当科で経験した縦隔胚細胞腫瘍切除例の検討, 第33回日本呼吸器外科学会総会, May 2016.
344.	Koichiro Kajiura, Kazuya Kondo, 松本大資, Naoya Kawakita, Mitsuhiro Tsuboi, Hiroaki Toba, Yukikiyo Kawakami, Hiromitsu Takizawa, Shoji Sakiyama and Akira Tangoku : 胸腺上皮性腫瘍の新TNM分類の妥当性, 第33回日本呼吸器外科学会総会, May 2016.
345.	Naoya Kawakita, Hiromitsu Takizawa, Yukikiyo Kawakami, 乾友浩, 髙杉遥, 松本大資, Mitsuhiro Tsuboi, Koichiro Kajiura, Hiroaki Toba, Kazuya Kondo, Shoji Sakiyama and Akira Tangoku : 肝細胞癌肺転移における術中ICG蛍光観察の意義, 第33回日本呼吸器外科学会総会, May 2016.
346.	Yukikiyo Kawakami, 松本大資, Naoya Kawakita, Mitsuhiro Tsuboi, Koichiro Kajiura, Hiroaki Toba, Hiromitsu Takizawa, Mitsuteru Yoshida, Shoji Sakiyama, Kazuya Kondo and Akira Tangoku : 原発性肺癌術後の胸腔内リンパ節再発例の検討, 第33回日本呼吸器外科学会総会, May 2016.
347.	Mitsuhiro Tsuboi, Hiromitsu Takizawa, 松本大資, Naoya Kawakita, Koichiro Kajiura, Hiroaki Toba, Yukikiyo Kawakami, Shoji Sakiyama, Kazuya Kondo and Akira Tangoku : 非小細胞肺癌における胸膜浸潤とskipリンパ節転移の検討, 第33回日本呼吸器外科学会総会, May 2016.
348.	Hiroaki Toba, Shoji Sakiyama, 松本大資, Naoya Kawakita, Mitsuhiro Tsuboi, Koichiro Kajiura, Yukikiyo Kawakami, Mitsuteru Yoshida, Hiromitsu Takizawa, Kazuya Kondo and Akira Tangoku : Ⅰ期非小細胞肺癌に対する消極的部分切除, 第33回日本呼吸器外科学会総会, May 2016.
349.	Hiromitsu Takizawa, Koichiro Kajiura, Mitsuhiro Tsuboi, Hiroaki Toba, 松本大資, Naoya Kawakita, Takeshi Nishino, Yukikiyo Kawakami, Mitsuteru Yoshida, Shoji Sakiyama, Kazuya Kondo and Akira Tangoku : 術前CTリンパ管造影による肺癌センチネルリンパ節同定, 第33回日本呼吸器外科学会総会, May 2016.
350.	Shoji Sakiyama, Koichiro Kajiura, 乾友浩, 松本大資, Naoya Kawakita, Mitsuhiro Tsuboi, Hiroaki Toba, Yukikiyo Kawakami, Hiromitsu Takizawa, Kazuya Kondo and Akira Tangoku : 分葉不全部を右S6からS2に広がる非浸潤肺癌に対して完全胸腔鏡下にS6+S2区域切除を施行した一例, 第33回日本呼吸器外科学会総会, May 2016.
351.	湊将典, 上田紗代, Taichi Murakami, 小野広幸, Sakiya Yoshimoto, 柴田恵理子, 田蒔昌憲, 岸史, Seiji Kishi, Motokazu Matsuura, Kojiro Nagai, Hideharu Abe, Toshio Doi, 近藤真代, Satoshi Sakaguchi, Yasuhiko Nishioka, 新井悠太, Takayoshi Shinya, Youichi Otomi, 河北直也, Hiromitsu Takizawa, Koichiro Kajiura and Shoji Sakiyama : 横隔膜交通症の診断および交通部位同定に腹腔シンチグラフィが有用であった1例, 第252回徳島医学会学術集会, Feb. 2016.
352.	Koichiro Kajiura, Kazuya Kondo, Mitsuhiro Tsuboi, Hiroaki Toba, Hiromitsu Takizawa, Yukikiyo Kawakami, Shoji Sakiyama and Akira Tangoku : 胸腺神経内分泌腫瘍におけるRASSF1のDNAメチル化, 第35回日本胸腺研究会, Feb. 2016.
353.	Mitsuhiro Tsuboi, Kazuya Kondo, Koichiro Kajiura, 乾友浩, 髙杉遥, 松本大資, 河北直也, Hiroaki Toba, Yukikiyo Kawakami, Hiromitsu Takizawa, Shoji Sakiyama and Akira Tangoku : PET-CTで広汎にFDG陽性リンパ節を伴ったリンパ濾胞性胸腺過形成の1例, 第35回日本胸腺研究会, Feb. 2016.
354.	Hiroaki Toba, Shoji Sakiyama, 松本大資, 河北直也, Mitsuhiro Tsuboi, Koichiro Kajiura, Yukikiyo Kawakami, Hiromitsu Takizawa, Kazuya Kondo and Akira Tangoku : 繰り返す喀血に対して極細径気管支鏡で確認できた気管支動脈瘤の1例, 第24回日本呼吸器内視鏡学会中国四国支部会, Dec. 2015.
355.	Takeshi Nishino, Takahiro Yoshida, Hiromitsu Takizawa, 乾友浩, 髙杉遥, 松本大資, 井上聖也, 河北直也, Mitsuhiro Tsuboi, Koichiro Kajiura, Hiroaki Toba, Yukikiyo Kawakami, Shoji Sakiyama, Kazuya Kondo and Akira Tangoku : 胸部外科領域における周術期口腔機能管理の術後肺炎予防効果, 第77回日本臨床外科学会総会, Nov. 2015.
356.	Koichiro Kajiura, Shoji Sakiyama, 松本大資, 河北直也, Mitsuhiro Tsuboi, Hiroaki Toba, Yukikiyo Kawakami, Hiromitsu Takizawa, Kazuya Kondo and Akira Tangoku : 肺癌手術症例の術前予後予測因子としてのmGPSとNLRの検討, 第56回日本肺癌学会総会, Nov. 2015.
357.	松本大資, Yukikiyo Kawakami, Hiromitsu Takizawa, Kazuya Kondo, 乾友浩, 髙杉遥, 河北直也, Takeshi Nishino, Mitsuhiro Tsuboi, Koichiro Kajiura, Hiroaki Toba, Shoji Sakiyama and Akira Tangoku : 肺葉切除22年後に胸壁転移を来したALK遺伝子変異陽性肺癌の1例, 第56回日本肺癌学会総会, Nov. 2015.
358.	Mitsuhiro Tsuboi, 松本大資, 河北直也, Koichiro Kajiura, Hiroaki Toba, Yukikiyo Kawakami, Hiromitsu Takizawa, Shoji Sakiyama, Kazuya Kondo and Akira Tangoku : 進行肺癌に対する術前化学放射線療法の検討, 第56回日本肺癌学会総会, Nov. 2015.
359.	河北直也, Shoji Sakiyama, Mitsuhiro Tsuboi, 乾友浩, 髙杉遥, 松本大資, Koichiro Kajiura, Hiroaki Toba, Yukikiyo Kawakami, Hiromitsu Takizawa, Kazuya Kondo and Akira Tangoku : 《口演》転移性肺腫瘍に対する完全胸腔鏡下S7区域切除術の1例, 第56回日本肺癌学会総会, Nov. 2015.
360.	Hiromitsu Takizawa, Kazuya Kondo, 乾友浩, 髙杉遥, 松本大資, 河北直也, Takeshi Nishino, Mitsuhiro Tsuboi, Koichiro Kajiura, Hiroaki Toba, Yukikiyo Kawakami, Mitsuteru Yoshida, Shoji Sakiyama and Akira Tangoku : 《口演》胸膜の自家蛍光減弱は肺癌の浸潤性を反映する, 第56回日本肺癌学会総会, Nov. 2015.
361.	Mitsuhiro Tsuboi, Hiromitsu Takizawa, 乾友浩, 髙杉遥 and Akira Tangoku : 妊娠を機に増大した甲状腺低分化癌の1例, 第48回日本甲状腺外科学会学術集会, Oct. 2015.
362.	Takeshi Nishino, Hiromitsu Takizawa, 乾友浩, 髙杉遥, 松本大資, 河北直也, Mitsuhiro Tsuboi, Koichiro Kajiura, Hiroaki Toba, Yukikiyo Kawakami, Shoji Sakiyama, Kazuya Kondo and Akira Tangoku : 周術期口腔機能管理の肺癌術後肺炎予防効果についての検討, 第68回日本胸部外科学会定期学術集会, Oct. 2015.
363.	Hirokazu Takechi, 森本雅美, Takeshi Nishino, Misako Nakagawa, Hiroaki Toba, Takahiro Yoshida, Yukikiyo Kawakami, Hiromitsu Takizawa, Yukiko Tadokoro and Akira Tangoku : 乳癌脳転移に対して全脳照射実施後に認知機能低下をきたした2例, 第12回日本乳癌学会中国四国地方会, Sep. 2015.
364.	髙杉遥, Hiroaki Toba, Shoji Sakiyama, 河北直也, Mitsuhiro Tsuboi, Koichiro Kajiura, Yukikiyo Kawakami, Hiromitsu Takizawa, Kazuya Kondo and Akira Tangoku : 胸腺腫再発5年後という晩期に赤芽球癆を発症し，シクロスポリンにて症状の改善を認めた1例, 第90回中国四国外科学会総会, Sep. 2015.
365.	河北直也, Hiroaki Toba, 乾友浩, 髙杉遥, Mitsuhiro Tsuboi, Koichiro Kajiura, Yukikiyo Kawakami, Hiromitsu Takizawa, Kazuya Kondo and Shoji Sakiyama : 縦隔悪性胚細胞性腫瘍に対するBEP療法中に発症した間質性肺炎後の手術療法の1例, 第53回日本呼吸器学会中国・四国地方会/第54回日本肺癌学会中国・四国支部会, Jul. 2015.
366.	Hiromitsu Takizawa : 右上葉切除術における不全分葉の対処法, Minimally invasive Thoracic Surgery the 3rd seminar, Jun. 2015.
367.	河北直也, Hiroaki Toba, Shoji Sakiyama, Takanori Miyoshi, Mitsuhiro Tsuboi, Koichiro Kajiura, Yasushi Nakagawa, Yukikiyo Kawakami, Mitsuteru Yoshida, Hiromitsu Takizawa, Kazuya Kondo and Akira Tangoku : 小型末梢肺病変の安全確実な鏡視下切除のためのCTガイド下気管支鏡下コイルマーキング, 第40回日本外科系連合学会学術集会, Jun. 2015.
368.	Hiromitsu Takizawa, 笠松哲司, Hirokazu Takechi, Yasushi Nakagawa, 坂本晋一, 住友弘幸, Mitsuhiro Tsuboi and Akira Tangoku : 《シンポジウム》甲状腺未分化癌治療を支える病診連携の重要性, 第40回日本外科系連合学会学術集会, Jun. 2015.
369.	乾友浩, Hiromitsu Takizawa, Kazuya Kondo, Yukikiyo Kawakami, 坂本晋一, 住友弘幸, Takeshi Nishino, Mitsuhiro Tsuboi, Koichiro Kajiura, Hiroaki Toba, Yasushi Nakagawa, Shoji Sakiyama and Akira Tangoku : 肺大細胞癌術後空調転移に対して手術と化学療法を行い長期生存が得られた1例, 第58回関西胸部外科学会学術集会, Jun. 2015.
370.	Koichiro Kajiura, Shoji Sakiyama, Mitsuhiro Tsuboi, Hiroaki Toba, Yasushi Nakagawa, Yukikiyo Kawakami, Hiromitsu Takizawa, Kazuya Kondo and Akira Tangoku : 気道確保を要した気管支鏡下生検による気道出血症例, 第38回日本呼吸器内視鏡学会学術集会, Jun. 2015.
371.	坂本晋一, Koichiro Kajiura, Kazuya Kondo, 住友弘幸, Mitsuhiro Tsuboi, Hiroaki Toba, Yasushi Nakagawa, Yukikiyo Kawakami, Hiromitsu Takizawa, Shoji Sakiyama and Akira Tangoku : 梗塞性壊死を伴う嚢胞性胸腺腫の検討, 第32回日本呼吸器外科学会総会, May 2015.
372.	Hiromitsu Takizawa, Shoji Sakiyama, 坂本晋一, 西野豪志, Mitsuhiro Tsuboi, Koichiro Kajiura, Hiroaki Toba, Yasushi Nakagawa, Yukikiyo Kawakami, Mitsuteru Yoshida, Akira Tangoku and Kazuya Kondo : 大腸癌肺転移切除例の検討, 第32回日本呼吸器外科学会総会, May 2015.
373.	Koichiro Kajiura, Shoji Sakiyama, 坂本晋一, 住友弘幸, Mitsuhiro Tsuboi, Hiroaki Toba, Yasushi Nakagawa, Yukikiyo Kawakami, Hiromitsu Takizawa, Kazuya Kondo and Akira Tangoku : 微小乳頭状パターンを伴う肺癌症例の検討, 第32回日本呼吸器外科学会総会, May 2015.
374.	住友弘幸, Hiroaki Toba, 坂本晋一, 西野豪志, Mitsuhiro Tsuboi, Koichiro Kajiura, Yasushi Nakagawa, Yukikiyo Kawakami, Hiromitsu Takizawa, Akira Tangoku and Kazuya Kondo : 左上葉肺癌術後に生じた右難治性気胸の一例, 第32回日本呼吸器外科学会総会, May 2015.
375.	Yukikiyo Kawakami, 坂本晋一, 住友弘幸, Mitsuhiro Tsuboi, Koichiro Kajiura, Hiroaki Toba, Yasushi Nakagawa, Hiromitsu Takizawa, Mitsuteru Yoshida, Shoji Sakiyama, Kazuya Kondo and Akira Tangoku : 左下葉肺門部肺癌に対し，下葉+舌区切除および気管支管状切除にて左肺全摘を回避できた一例, 第32回日本呼吸器外科学会総会, May 2015.
376.	Mitsuhiro Tsuboi, Hiromitsu Takizawa, 坂本晋一, 住友弘幸, 西野豪志, Koichiro Kajiura, Hiroaki Toba, Yasushi Nakagawa, Yukikiyo Kawakami, Shoji Sakiyama, Kazuya Kondo and Akira Tangoku : 末梢小型肺癌における胸膜浸潤とFDG集積の検討, 第32回日本呼吸器外科学会総会, May 2015.
377.	Hiroaki Toba, Shoji Sakiyama, Mitsuhiro Tsuboi, Koichiro Kajiura, Yasushi Nakagawa, Yukikiyo Kawakami, Hiromitsu Takizawa, Kazuya Kondo and Akira Tangoku : 肺癌術後無症候性患者でのPET/CTを用いたフォローアップ, 第32回日本呼吸器外科学会総会, May 2015.
378.	西野豪志, Hiromitsu Takizawa, 住友弘幸, 坂本晋一, Mitsuhiro Tsuboi, Koichiro Kajiura, Hiroaki Toba, Yasushi Nakagawa, Yukikiyo Kawakami, Shoji Sakiyama, Kazuya Kondo and Akira Tangoku : 原発性肺癌における周術期口腔機能管理の有用性について, 第32回日本呼吸器外科学会総会, May 2015.
379.	Shoji Sakiyama, Hiroaki Toba, Yukikiyo Kawakami, Koichiro Kenzaki, Mitsuhiro Tsuboi, Koichiro Kajiura, Yasushi Nakagawa, Hiromitsu Takizawa, Kazuya Kondo and Akira Tangoku : 胎生期肺組織移植による肺の再生と修復, 第55回日本呼吸器学会学術講演会, Apr. 2015.
380.	Misako Nakagawa, 坂本晋一, 住友弘幸, 森本雅美, 西野豪志, Mitsuhiro Tsuboi, Yoshihito Furukita, Koichiro Kajiura, Hirokazu Takechi, Takahiro Yoshida, Yasushi Nakagawa, Hiromitsu Takizawa, Yukiko Tadokoro, Shoji Sakiyama and Akira Tangoku : CTリンパ管造影によるセンチネルリンパ節の転移診断, 第115回日本外科学会定期学術集会, Apr. 2015.
381.	Yukikiyo Kawakami, 坂本晋一, 住友弘幸, Mitsuhiro Tsuboi, Koichiro Kajiura, Hiroaki Toba, Yasushi Nakagawa, Hiromitsu Takizawa, Shoji Sakiyama, Kazuya Kondo and Akira Tangoku : 左肺上葉切除は術後動脈血栓症の危険因子か?-各肺葉切除後，肺静脈断端血栓の有無の比較-, 第115回日本外科学会定期学術集会, Apr. 2015.
382.	Hiromitsu Takizawa, 坂本晋一, 住友弘幸, 西野豪志, Mitsuhiro Tsuboi, Koichiro Kajiura, Hiroaki Toba, Yasushi Nakagawa, Yukikiyo Kawakami, Mitsuteru Yoshida, Shoji Sakiyama, Kazuya Kondo and Akira Tangoku : データ解析に基づいたVATS肺葉切除術における術式工夫, 第115回日本外科学会定期学術集会, Apr. 2015.
383.	Kazuya Kondo, 中島淳, 奥村明之進, 吉野一郎, 藤井義敬, 浅村尚生, 吉田和夫, 伊達洋至, 横井香平, Shoji Sakiyama, Hiromitsu Takizawa, Yasushi Nakagawa, Koichiro Kajiura, Yukikiyo Kawakami and Akira Tangoku : 胸腺上皮性腫瘍のリンパ節転移・遠隔転移に対する治療戦略, 第115回日本外科学会定期学術集会, Apr. 2015.
384.	Naoto Uyama, Hideki Otsuka, Youichi Otomi, Masafumi Harada, Hitoshi Ikushima, Taito Yamago, Yuko Toyoda, Masaki Hanibuchi, Yasuhiko Nishioka, Hiromitsu Takizawa and Yoshimi Bando : 特異な経過を示した肺原発滑膜肉腫の一例, 第7回呼吸機能イメージング研究会学術集会, Feb. 2015.
385.	乾友浩, Mitsuhiro Tsuboi, 坂本晋一, 住友弘幸, Koichiro Kajiura, Hiroaki Toba, Yasushi Nakagawa, Yukikiyo Kawakami, Hiromitsu Takizawa, Shoji Sakiyama, Kazuya Kondo and Akira Tangoku : 喀血を繰り返した気管支動脈蔓状血管腫の1例, 第76回日本臨床外科学会総会, Nov. 2014.
386.	猪子未希, Mitsuhiro Tsuboi, 坂本晋一, 住友弘幸, Koichiro Kajiura, Hiroaki Toba, Yasushi Nakagawa, Yukikiyo Kawakami, Hiromitsu Takizawa, Shoji Sakiyama, Kazuya Kondo and Akira Tangoku : 肺癌術後間質性肺炎急性増悪4例の検討, 第76回日本臨床外科学会総会, Nov. 2014.
387.	住友弘幸, 西野豪志, 坂本晋一, Yoshihito Furukita, Takahiro Yoshida, Hirokazu Takechi, Jun-ichi Seike, Hiromitsu Takizawa and Akira Tangoku : バセドウ病に合併し，甲状腺亜全摘と食道憩室切除を同時に行ったKillian-Jamieson憩室の一例, 第76回日本臨床外科学会総会, Nov. 2014.
388.	Mitsuhiro Tsuboi, Hiromitsu Takizawa, Koichiro Kajiura, 坂本晋一, 住友弘幸, Hiroaki Toba, Yasushi Nakagawa, Yukikiyo Kawakami, Shoji Sakiyama, Kazuya Kondo and Akira Tangoku : 肺区域切除におけるICG静注による新たな区域間同定法, 第76回日本臨床外科学会総会, Nov. 2014.
389.	Mitsuhiro Tsuboi, Hiromitsu Takizawa, 坂本晋一, 住友弘幸, 西野豪志, Koichiro Kajiura, Hiroaki Toba, Yasushi Nakagawa, Yukikiyo Kawakami, Shoji Sakiyama, Kazuya Kondo and Akira Tangoku : 《パネルディスカッション》難治性気胸に対する治療戦略-気管支塞栓術と胸腔内フィブリン糊注入療法の比較-, 第76回日本臨床外科学会総会, Nov. 2014.
390.	Takae Bando, Kazuya Kondo, 劉環, Yoshie Imai, Koichiro Kajiura, Yukikiyo Kawakami, Yasushi Nakagawa, Mitsuteru Yoshida, Hiromitsu Takizawa, Shoji Sakiyama, Hiroaki Toba, Chiemi Onishi and Akira Tangoku : 手術療法施行した肺がん患者のpatient reported quality of life(PRQOL)及び心理状態のの評価(第2報), 第55回日本肺癌学会学術集会, Nov. 2014.
391.	Hiromitsu Takizawa, 住友弘幸, 坂本晋一, 西野豪志, Mitsuhiro Tsuboi, Koichiro Kajiura, Hiroaki Toba, Yasushi Nakagawa, Yukikiyo Kawakami, Mitsuteru Yoshida, Shoji Sakiyama, Akira Tangoku, Kazuya Kondo, 森下敦司, 河北直也 and 広瀬敏幸 : 自家蛍光内視鏡による胸膜浸潤診断能の検証, 第55回日本肺癌学会学術集会, Nov. 2014.
392.	Hiromitsu Takizawa, Mitsuhiro Tsuboi, Hirokazu Takechi, Yasushi Nakagawa and Akira Tangoku : 甲状腺未分化癌に対するSorafenibによる治療経験, 第47回日本甲状腺外科学会学術集会, Oct. 2014.
393.	Mitsuhiro Tsuboi, 坂本晋一, 住友弘幸, Misako Nakagawa, Yasushi Nakagawa, Hiromitsu Takizawa and Akira Tangoku : 経口フッ化ピリミジン系抗がん剤による維持療法にて5年の長期生存が得られた甲状腺未分化癌の1例, 第47回日本甲状腺外科学会学術集会, Oct. 2014.
394.	Yasushi Nakagawa, Mitsuhiro Tsuboi, Hiromitsu Takizawa and Akira Tangoku : 甲状腺悪性リンパ腫と鑑別を要したIgG4甲状腺炎の1例, 第47回日本甲状腺外科学会学術集会, Oct. 2014.
395.	Yoshiko Yamamura, Hiromitsu Takizawa, Fumihiro Matsumoto, Yukihiro Momota, Keiko Aota, Daisuke Takegawa, Kohichi Kani, Hideyuki Takano, 山ノ井朋子, 近藤智香, 金川裕子, 高瀬奈緒, Yuka Sogawa and Masayuki Azuma : 肺癌患者における周術期口腔機能管理の有用性について-術後合併症の観点より-, 第62回NPO法人日本口腔科学会中国・四国地方部会, Oct. 2014.
396.	Yukikiyo Kawakami, Mitsuhiro Tsuboi, Koichiro Kajiura, Hiroaki Toba, Yasushi Nakagawa, Hiromitsu Takizawa, Shoji Sakiyama, Kazuya Kondo and Akira Tangoku : 病理病期1期，非小細胞肺癌術後再発例の検討, 第67回日本胸部外科学会定期学術集会, Sep. 2014.
397.	Takahiro Yoshida, Yoshihito Furukita, 西野豪志, 坂本晋一, 住友弘幸, Mitsuhiro Tsuboi, Koichiro Kajiura, Hiroaki Toba, Yasushi Nakagawa, Yukikiyo Kawakami, Hiromitsu Takizawa, Shoji Sakiyama, Kazuya Kondo and Akira Tangoku : 《口演》開胸食道切除術後の心血管イベント発症防止に対する塩酸ランジオロールの周術期投与の有用性に関する検討, 第67回日本胸部外科学会定期学術集会, Sep. 2014.
398.	Shoji Sakiyama, Hiroaki Toba, Mitsuteru Yoshida, Yukikiyo Kawakami, Koichiro Kenzaki, Mitsuhiro Tsuboi, Koichiro Kajiura, Yasushi Nakagawa, Hiromitsu Takizawa, Kazuya Kondo and Akira Tangoku : 《口演》胎生期肺組織移植におけるglucocorticoid投与は移植肺組織においてelastinの発現を促進する, 第67回日本胸部外科学会定期学術集会, Sep. 2014.
399.	Yoshihito Furukita, Akira Tangoku, 住友弘幸, 坂本晋一, 西野豪志, Hirokazu Takechi, Takahiro Yoshida, Jun-ichi Seike and Hiromitsu Takizawa : 食道良性疾患に対するda Vinci手術の経験, 第89回中国四国外科学会総会・第19回中国四国内視鏡外科研究会, Sep. 2014.
400.	Mitsuhiro Tsuboi, 森下敦司, Koichiro Kajiura, Hiroaki Toba, Yasushi Nakagawa, Yukikiyo Kawakami, Hiromitsu Takizawa, Shoji Sakiyama, Kazuya Kondo and Akira Tangoku : 《要望ビデオセッション:手術手技》呼吸器外科手術におけるPowered ECHELON FLEXTMの使用経験, 第57回関西胸部外科学会学術集会, Jun. 2014.
401.	坂本晋一, Koichiro Kajiura, Hirokazu Takechi, 森下敦司, Mitsuhiro Tsuboi, Hiroaki Toba, Mitsuteru Yoshida, Yukikiyo Kawakami, Hiromitsu Takizawa, Kazuya Kondo and Akira Tangoku : 診断困難であったgefitinib投与中に発生した肺癌術後脳転移の1例, 第31回日本呼吸器外科学会総会, May 2014.
402.	Shoji Sakiyama, Hiromitsu Takizawa, Yukikiyo Kawakami, Kazuya Kondo, Akira Tangoku, 浜口伸正, 吉澤潔, 木村秀, 住友正幸, Takanori Miyoshi and 日野弘之 : 呼吸器外科専門医の育成と維持-地域の現状と今後-, 第31回日本呼吸器外科学会総会, May 2014.
403.	住友弘幸, Hiromitsu Takizawa, Shoji Sakiyama, Mitsuteru Yoshida, 坂本晋一, 森下敦司, 西野豪志, Mitsuhiro Tsuboi, Koichiro Kajiura, Yasushi Nakagawa, Yukikiyo Kawakami, Akira Tangoku and Kazuya Kondo : 肺原発滑膜肉腫の1切除例, 第31回日本呼吸器外科学会総会, May 2014.
404.	Yukikiyo Kawakami, Mitsuhiro Tsuboi, Koichiro Kajiura, Hiroaki Toba, Yasushi Nakagawa, Hiromitsu Takizawa, Mitsuteru Yoshida, Shoji Sakiyama, Kazuya Kondo and Akira Tangoku : 発症から数ヵ月を経て診断された後，異なる治療経過をたどった肺切除後，気管支断端瘻の2例, 第31回日本呼吸器外科学会総会, May 2014.
405.	森下敦司, Hiromitsu Takizawa, Kazuya Kondo, 西野豪志, Mitsuhiro Tsuboi, Koichiro Kajiura, Hiroaki Toba, Yasushi Nakagawa, Mitsuteru Yoshida, Yukikiyo Kawakami, Akira Tangoku, 河北直也, 広瀬敏幸 and 住友正幸 : 胸膜浸潤の術中評価はどの程度正確か, 第31回日本呼吸器外科学会総会, May 2014.
406.	Koichiro Kajiura, Shoji Sakiyama, 森下敦司, Mitsuhiro Tsuboi, Hiroaki Toba, Yasushi Nakagawa, Yukikiyo Kawakami, Hiromitsu Takizawa, Mitsuteru Yoshida, Kazuya Kondo and Akira Tangoku : 《一般ビデオ》ジェット換気を用いた気管腺様嚢胞癌に対する気管環状切除の1例, 第31回日本呼吸器外科学会総会, May 2014.
407.	Mitsuhiro Tsuboi, Hiromitsu Takizawa, 森下敦司, 西野豪志, Koichiro Kajiura, Hiroaki Toba, Yasushi Nakagawa, Mitsuteru Yoshida, Yukikiyo Kawakami, Shoji Sakiyama, Kazuya Kondo and Akira Tangoku : 《一般口演》肺癌手術症例における胸膜浸潤とリンパ節転移に関する検討, 第31回日本呼吸器外科学会総会, May 2014.
408.	Hiromitsu Takizawa, Kazuya Kondo, Koichiro Kajiura, 森下敦司, 西野豪志, Mitsuhiro Tsuboi, Hiroaki Toba, Yasushi Nakagawa, Mitsuteru Yoshida, Yukikiyo Kawakami, Shoji Sakiyama and Akira Tangoku : 《要望ビデオ》胸膜の自家蛍光を用いた胸膜浸潤の術中診断, 第31回日本呼吸器外科学会総会, May 2014.
409.	西野豪志, Shoji Sakiyama, 森下敦司, Mitsuhiro Tsuboi, Koichiro Kajiura, Hiromitsu Takizawa, Mitsuteru Yoshida, Yukikiyo Kawakami, Kazuya Kondo and Akira Tangoku : 《要望演題》難治性気胸に対する治療戦略∼当科における胸腔内フィブリン糊注入療法の成績と工夫∼, 第31回日本呼吸器外科学会総会, May 2014.
410.	長瀬紗季, Koichiro Kajiura, Hiromitsu Takizawa, 森下敦司, Mitsuhiro Tsuboi, Hiroaki Toba, Yasushi Nakagawa, Mitsuteru Yoshida, Yukikiyo Kawakami, Shoji Sakiyama, Kazuya Kondo and Akira Tangoku : 慢性有ろう性膿胸に対する人工呼吸管理下のEWSによる気管支充填術が有効であった1例, 第37回日本呼吸器内視鏡学会学術集会, Apr. 2014.
411.	Shoji Sakiyama, Hiroaki Toba, Koichiro Kenzaki, Mitsuhiro Tsuboi, Koichiro Kajiura, Yasushi Nakagawa, Mitsuteru Yoshida, Yukikiyo Kawakami, Hiromitsu Takizawa, Kazuya Kondo and Akira Tangoku : 胎生期肺組織移植における気道系の分化とbranchingに関する検討, 第37回日本呼吸器内視鏡学会学術集会, Apr. 2014.
412.	Shoji Sakiyama, 森下敦司, Mitsuhiro Tsuboi, Koichiro Kajiura, Hiroaki Toba, Yasushi Nakagawa, Mitsuteru Yoshida, Yukikiyo Kawakami, Hiromitsu Takizawa, Kazuya Kondo and Akira Tangoku : 気管支鏡関連医療事故の分析とその対応を考える, 第37回日本呼吸器内視鏡学会学術集会, Apr. 2014.
413.	Hiromitsu Takizawa, Kazuya Kondo, Koichiro Kajiura, Mitsuhiro Tsuboi, 森下敦司, Hiroaki Toba, Yasushi Nakagawa, Mitsuteru Yoshida, Yukikiyo Kawakami, Shoji Sakiyama and Akira Tangoku : 自家蛍光観察による胸膜浸潤の術中診断精度向上にむけた取り組み, 第37回日本呼吸器内視鏡学会学術集会, Apr. 2014.
414.	Shoji Sakiyama, Hiromitsu Takizawa, Koichiro Kajiura, Mitsuhiro Tsuboi, Yasushi Nakagawa, Mitsuteru Yoshida, Yukikiyo Kawakami, Kazuya Kondo and Akira Tangoku : 《ビデオシンポジウム》肺癌に対するロボット補助下肺葉切除術-とくに触覚の決如に関して-, 第114回日本外科学会定期学術集会, Apr. 2014.
415.	Hiromitsu Takizawa, Kazuya Kondo, Koichiro Kajiura, Mitsuhiro Tsuboi, Hiroaki Toba, Yasushi Nakagawa, Mitsuteru Yoshida, Yukikiyo Kawakami, Shoji Sakiyama and Akira Tangoku : 《シンポジウム》肺癌区域切除におけるリンパ節転移と胸膜浸潤の術中診断精度向上に向けた取り組み, 第114回日本外科学会定期学術集会, Apr. 2014.
416.	Koichiro Kajiura, Shoji Sakiyama, Mitsuhiro Tsuboi, Mitsuteru Yoshida, 森下敦司, Hiroaki Toba, Yasushi Nakagawa, Yukikiyo Kawakami, Hiromitsu Takizawa, Kazuya Kondo and Akira Tangoku : 術前気道確保に気管支鏡下高周波スネア切除術が有効であった気管腺様嚢胞癌の1例, 第22回日本呼吸器内視鏡学会中国四国支部会, Feb. 2014.
417.	高橋直希, Atsuro Saijo, Souji Kakiuchi, Masaki Hanibuchi, Hiromitsu Takizawa, Takeshi Nishino, 森住俊, 岸昌美, Katsuhiro Kinoshita, Hisatsugu Goto, Youichi Otomi, Hitoshi Ikushima, Shoji Sakiyama and Yasuhiko Nishioka : PET/CTにて集積を認めなかった嚢胞状縦隔リンパ節腫大を伴う肺腺癌の一例, 第6回呼吸機能イメージング研究会学術集会, Jan. 2014.
418.	Tamaki Otani, Hideki Otsuka, Kazuya Kondo, Hiromitsu Takizawa and Hirokazu Miyoshi : 肺癌同所移植モデルマウスの18F-FDG PET/CTイメージング, 日本放射線安全管理学会第12回学術大会, Nov. 2013.
419.	劉環, Kazuya Kondo, Takae Bando, Koichiro Kajiura, Yoshie Imai, Yukikiyo Kawakami, Yasushi Nakagawa, Mitsuteru Yoshida, Hiromitsu Takizawa, Shoji Sakiyama and Akira Tangoku : 手術療法施行した肺がん患者におけるpatient reported quality of life(PRQOL)の評価, 第54回日本肺癌学会総会, Nov. 2013.
420.	Hiromitsu Takizawa, Kazuya Kondo, Tamaki Otani, Hideki Otsuka, Mitsuhiro Tsuboi, Koichiro Kajiura, Yasushi Nakagawa, Mitsuteru Yoshida, Yukikiyo Kawakami, Shoji Sakiyama and Akira Tangoku : PET/CTによるヒト肺癌細胞株肺移植モデルマウスの腫瘍評価, 第54回日本肺癌学会総会, Nov. 2013.
421.	Yasushi Nakagawa, Kazuya Kondo, Shoji Sakiyama, Yukikiyo Kawakami, Hiromitsu Takizawa, Mitsuteru Yoshida, Koichiro Kajiura, Mitsuhiro Tsuboi and Akira Tangoku : 胸腺上皮性腫瘍83例の検討, 第54回日本肺癌学会総会, Nov. 2013.
422.	Yukikiyo Kawakami, Mitsuhiro Tsuboi, Koichiro Kajiura, Yasushi Nakagawa, Hiromitsu Takizawa, Mitsuteru Yoshida, Shoji Sakiyama, Kazuya Kondo and Akira Tangoku : 当科における異時性多発肺癌手術例の検討, 第54回日本肺癌学会総会, Nov. 2013.
423.	Koichiro Kajiura, Shoji Sakiyama, 森下敦司, 西野豪志, Mitsuhiro Tsuboi, Yoshihito Furukita, Hirokazu Takechi, Takahiro Yoshida, Yasushi Nakagawa, Mitsuteru Yoshida, Yukikiyo Kawakami, Hiromitsu Takizawa, Kazuya Kondo and Akira Tangoku : 褐色細胞腫肺転移の1切除例, 第75回日本臨床外科学会総会, Nov. 2013.
424.	Hirokazu Takechi, Hiromitsu Takizawa, Yota Yamamoto, 西野豪志, 古川尊子, Koichiro Kajiura, 森本雅美, Misako Nakagawa, Yukiko Tadokoro, Shoji Sakiyama and Akira Tangoku : 癌性胸膜炎加療数日後に癌性心膜炎から心タンポナーデを発症しOncological emergencyに陥った再発乳癌の1例, 第75回日本臨床外科学会総会, Nov. 2013.
425.	乾友浩, Hirokazu Takechi, Hiromitsu Takizawa, Yasushi Nakagawa, Mitsuhiro Tsuboi, 新井悠太, 森下敦司, 西野豪志, Koichiro Kajiura, Yoshihito Furukita, Takahiro Yoshida and Akira Tangoku : 縦隔内甲状腺腫の2切除例, 第75回日本臨床外科学会総会, Nov. 2013.
426.	Koichiro Kajiura, Kazuya Kondo, Hiromitsu Takizawa, Mitsuhiro Tsuboi, Hiroaki Toba, Yasushi Nakagawa, Yukikiyo Kawakami, Mitsuteru Yoshida, Yoshihito Furukita, 西野豪志, Takahiro Yoshida, Shoji Sakiyama and Akira Tangoku : 胸腺腫術後再発治療の検討, 第66回日本胸部外科学会定期学術集会, Oct. 2013.
427.	Mitsuteru Yoshida, Shoji Sakiyama, 日野弘之, 高嶋美佳, Mitsuhiro Tsuboi, Koichiro Kajiura, Hiroaki Toba, Yasushi Nakagawa, Hiromitsu Takizawa, Yukikiyo Kawakami, Kazuya Kondo and Akira Tangoku : 解剖学的破格を伴う胸部手術症例, 第66回日本胸部外科学会定期学術集会, Oct. 2013.
428.	Shoji Sakiyama, Mitsuteru Yoshida, Yukikiyo Kawakami, Koichiro Kenzaki, Mitsuhiro Tsuboi, Koichiro Kajiura, Yasushi Nakagawa, Hiromitsu Takizawa, Kazuya Kondo and Akira Tangoku : 胎生期肺組織移植におけるGlucocorticoid投与は移植肺の分化を促進する, 第66回日本胸部外科学会定期学術集会, Oct. 2013.
429.	Yasushi Nakagawa, Hiromitsu Takizawa, Mitsuhiro Tsuboi and Akira Tangoku : 反回神経麻痺をきたした腺腫様甲状腺腫の1例, 第46回日本甲状腺外科学会学術集会, Sep. 2013.
430.	Mitsuhiro Tsuboi, Hiromitsu Takizawa, Yasushi Nakagawa, Hirokazu Takechi, 西野豪志, 森本雅美, 森下敦司 and Akira Tangoku : 長期生存を得ている甲状腺髄様癌術後肝転移の1例, 第46回日本甲状腺外科学会学術集会, Sep. 2013.
431.	Hirokazu Takechi, Hiromitsu Takizawa, Yota Yamamoto, 古川尊子, 西野豪志, Koichiro Kajiura, 森本雅美, Misako Nakagawa, Yukiko Tadokoro, Shoji Sakiyama and Akira Tangoku : 癌性胸膜炎加療数日後に癌性心膜炎から心タンポナーデを発症しOncological emergencyに陥った再発乳癌の1例, 第10回日本乳癌学会中国四国地方会, Sep. 2013.
432.	中林えみ, Hirokazu Takechi, Hiromitsu Takizawa, Yota Yamamoto, 古川尊子, 西野豪志, Koichiro Kajiura, 森本雅美, 森下敦司, Mitsuhiro Tsuboi, Misako Nakagawa, Yoshihito Furukita, Takahiro Yoshida, Yukiko Tadokoro, Shoji Sakiyama and Akira Tangoku : 癌性胸膜炎加療数日後に癌性心膜炎から心タンポナーデを発症しOncological emergencyに陥った再発乳癌の1例, 第88回中国四国外科学会総会, Sep. 2013.
433.	Misako Nakagawa, 森下敦司, 森本雅美, 西野豪志, Mitsuhiro Tsuboi, Koichiro Kajiura, Yoshihito Furukita, Hirokazu Takechi, Takahiro Yoshida, Yasushi Nakagawa, Yukikiyo Kawakami, Hiromitsu Takizawa, Mitsuteru Yoshida, Yukiko Tadokoro, Shoji Sakiyama and Akira Tangoku : データベースによる乳がん登録の問題点と当科における乳癌患者の傾向, 第88回中国四国外科学会総会, Sep. 2013.
434.	乾友浩, Hirokazu Takechi, Hiromitsu Takizawa, Yasushi Nakagawa, Mitsuhiro Tsuboi, 新井悠太, 森本雅美, 西野豪志, Misako Nakagawa, Yoshihito Furukita, Takahiro Yoshida, Yukiko Tadokoro and Akira Tangoku : 呼吸困難を呈した超高齢者発症縦隔内甲状腺腫瘤の1切除例, 第88回中国四国外科学会総会, Sep. 2013.
435.	Mitsuteru Yoshida, Shoji Sakiyama, 森下敦司, 西野豪志, Mitsuhiro Tsuboi, Koichiro Kajiura, Hiroaki Toba, Yasushi Nakagawa, Yukikiyo Kawakami, Hiromitsu Takizawa, Kazuya Kondo and Akira Tangoku : 呼吸器外科領域におけるQuantiFERON-TB検査の医療安全面からの有用性, 第49回日本呼吸器学会中国四国地方会・第52回日本肺癌学会中国四国支部会, Jul. 2013.
436.	森下敦司, Hiromitsu Takizawa, Mitsuhiro Tsuboi, Koichiro Kajiura, Yasushi Nakagawa, Mitsuteru Yoshida, Yukikiyo Kawakami, Shoji Sakiyama, Kazuya Kondo and Akira Tangoku : 甲状腺癌多発肺転移に原発性肺癌を合併した1例, 第49回日本呼吸器学会中国四国地方会・第52回日本肺癌学会中国四国支部会, Jul. 2013.
437.	池田真由美, Hiromitsu Takizawa, 古川尊子, 西野豪志, Koichiro Kajiura, Yasushi Nakagawa, Yukikiyo Kawakami, Mitsuteru Yoshida, Shoji Sakiyama, Kazuya Kondo and Akira Tangoku : 内科治療抵抗性の乳児気管支肉芽に対してHo : YAGレーザー焼灼術を施行した1例, 第36回日本呼吸器内視鏡学会学術集会, Jun. 2013.
438.	Hiromitsu Takizawa, Koichiro Kajiura, 池田真由美, 古川尊子, 西野豪志, 森本雅美, Yasushi Nakagawa, Mitsuteru Yoshida, Yukikiyo Kawakami, Shoji Sakiyama, Kazuya Kondo and Akira Tangoku : 《シンポジウム》術前経気管支水溶性造影剤注入CTリンパ管造影法による肺癌センチネルリンパ節同定, 第36回日本呼吸器内視鏡学会学術集会, Jun. 2013.
439.	Mitsuteru Yoshida, Shoji Sakiyama, 池田真由美, 古川尊子, 森本雅美, 西野豪志, Koichiro Kajiura, Hiroaki Toba, Yasushi Nakagawa, Yukikiyo Kawakami, Hiromitsu Takizawa, Kazuya Kondo and Akira Tangoku : 《ワークショップ》QuantiFERON-TB検査の呼吸器外科領域における医療安全面からの有用性, 第36回日本呼吸器内視鏡学会学術集会, Jun. 2013.
440.	Koichiro Kajiura, Shoji Sakiyama, Hiromitsu Takizawa, 池田真由美, 古川尊子, 森本雅美, Yasushi Nakagawa, Yukikiyo Kawakami, Mitsuteru Yoshida, Kazuya Kondo, Yuko Toyoda, Toshifumi Tezuka, Katsuhiro Kinoshita, Yoshinori Aono, Yasuhiko Nishioka and Akira Tangoku : 《ワークショップ》気管支鏡破損症例の検討, 第36回日本呼吸器内視鏡学会学術集会, Jun. 2013.
441.	池田真由美, 西野豪志, Shoji Sakiyama, Koichiro Kajiura, Yasushi Nakagawa, Mitsuteru Yoshida, Yukikiyo Kawakami, Hiromitsu Takizawa, Kazuya Kondo and Akira Tangoku : 胸腺腫術後に両側横隔神経麻痺による呼吸不全をきたした1例, 第56回関西胸部外科学会学術集会, Jun. 2013.
442.	Yukikiyo Kawakami, Koichiro Kajiura, Hiroaki Toba, Yasushi Nakagawa, Hiromitsu Takizawa, Mitsuteru Yoshida, Shoji Sakiyama, Kazuya Kondo and Akira Tangoku : 胸腺上皮性腫瘍におけるFDG PET-CTの有用性‐組織型，正岡分類との関連性につき-, 第30回日本呼吸器外科学会総会, May 2013.
443.	池田真由美, Mitsuteru Yoshida, Shoji Sakiyama, 古川尊子, Koichiro Kajiura, Hirokazu Takechi, Yasushi Nakagawa, Yukikiyo Kawakami, Hiromitsu Takizawa, Kazuya Kondo and Akira Tangoku : サルコイドーシス合併肺腺癌術後にSIADHを合併した1例, 第30回日本呼吸器外科学会総会, May 2013.
444.	Koichiro Kajiura, Hiromitsu Takizawa, Shoji Sakiyama, 古川尊子, 西野豪志, 森本雅美, Mitsuteru Yoshida, Yukikiyo Kawakami, Yasushi Nakagawa, Kazuya Kondo and Akira Tangoku : 塩酸ランジオロールの肺葉切除後上室性不整脈予防効果の検討, 第30回日本呼吸器外科学会総会, May 2013.
445.	古川尊子, Mitsuteru Yoshida, Shoji Sakiyama, 池田真由美, Koichiro Kajiura, Yasushi Nakagawa, Yukikiyo Kawakami, Hiromitsu Takizawa, Kazuya Kondo and Akira Tangoku : 非連続性多発性腫瘤を呈した悪性胸膜中皮腫の1手術例, 第30回日本呼吸器外科学会総会, May 2013.
446.	Mitsuteru Yoshida, Shoji Sakiyama, 池田真由美, 古川尊子, 森本雅美, 西野豪志, Koichiro Kajiura, Hiroaki Toba, Yasushi Nakagawa, Hiromitsu Takizawa, Yukikiyo Kawakami, Kazuya Kondo and Akira Tangoku : 侵襲型肺アスペルギルス症に対する右肺全摘術の経験, 第30回日本呼吸器外科学会総会, May 2013.
447.	Shoji Sakiyama, Hiromitsu Takizawa, Koichiro Kajiura, Yasushi Nakagawa, Yukikiyo Kawakami, Mitsuteru Yoshida, Kazuya Kondo and Akira Tangoku : 縦隔型舌区動脈を有する肺癌症例に対するロボット補助下左上葉切除術, 第30回日本呼吸器外科学会総会, May 2013.
448.	Hiromitsu Takizawa : ランチョンセミナー ``より見える!''胸腔鏡下手術へ, 第30回日本呼吸器外科学会総会, May 2013.
449.	Mitsuteru Yoshida, Kazuya Kondo, Yasushi Nakagawa, Koichiro Kajiura, Hiroaki Toba, Yukikiyo Kawakami, Hiromitsu Takizawa, Shoji Sakiyama and Akira Tangoku : 重症筋無力症患者の術前3D画像解析が拡大胸腺摘出術後の予後予測に及ぼす可能性, 第113回日本外科学会定期学術集会, Apr. 2013.
450.	Koichiro Kajiura, Yukikiyo Kawakami, 池田真由美, 古川尊子, 森本雅美, 西野豪志, Masakazu Goto, Misako Nakagawa, Yota Yamamoto, Yoshihito Furukita, Hirokazu Takechi, Yasushi Nakagawa, Mitsuteru Yoshida, Hiromitsu Takizawa, Yukiko Tadokoro, Shoji Sakiyama, Kazuya Kondo and Akira Tangoku : YAGレーザー使用時の気管支鏡破損の1例, 第21回日本呼吸器内視鏡学会中国四国支部会, Feb. 2013.
451.	古川尊子, Mitsuteru Yoshida, Koichiro Kajiura, Shoji Sakiyama, Hiromitsu Takizawa, 森本雅美, Hirokazu Takechi, 池田真由美, 西野豪志, Yasushi Nakagawa, Yukikiyo Kawakami, Kazuya Kondo and Akira Tangoku : 当科における気管支鏡検査へのLung pointの経験, 第21回日本呼吸器内視鏡学会中国四国支部会, Feb. 2013.
452.	池田真由美, Hiromitsu Takizawa, 古川尊子, 西野豪志, Masakazu Goto, Koichiro Kajiura, Yasushi Nakagawa, Yukikiyo Kawakami, Mitsuteru Yoshida, Shoji Sakiyama, Kazuya Kondo and Akira Tangoku : 内科的治療抵抗性の乳児気管支肉芽に対してHo:YAGレーザー焼灼術を施行した1例, 第21回日本呼吸器内視鏡学会中国四国支部会, Feb. 2013.
453.	高井ちか子, Yasushi Nakagawa, 大岩由香里, 藤田結衣, Hiromitsu Takizawa, Mitsuteru Yoshida, 川上行奎, 梶浦耕一郎, Shoji Sakiyama, Akira Tangoku, Yousuke Takahama and Kazuya Kondo : ヒト胸腺・胸腺腫における皮質・髄質 component の distribution, 第32回日本胸腺研究会, Feb. 2013.
454.	Koichiro Kajiura, Hiromitsu Takizawa, Kazuya Kondo, 池田真由美, 古川尊子, 西野豪志, Masakazu Goto, Yota Yamamoto, Yoshihito Furukita, 森本雅美, Mitsuteru Yoshida, Yasushi Nakagawa, Yukikiyo Kawakami, Shoji Sakiyama and Akira Tangoku : 周術期に骨髄異形成症候群を発症した肺小細胞癌の1例, 第74回日本臨床外科学会総会, Nov. 2012.
455.	西野豪志, Hiromitsu Takizawa, Koichiro Kajiura, Yasushi Nakagawa, Mitsuteru Yoshida, Yukikiyo Kawakami, Shoji Sakiyama, Kazuya Kondo and Akira Tangoku : 進行肺癌に合併した難治性続発性気胸に対する胸腔内フィブリン糊注入療法の有用性, 第74回日本臨床外科学会総会, Nov. 2012.
456.	Koichiro Kajiura, Hiromitsu Takizawa, 森本雅美, Yasushi Nakagawa, Mitsuteru Yoshida, Yukikiyo Kawakami, Shoji Sakiyama and Kazuya Kondo : GPS(Glasgow Prognstic Score)を用いた肺癌手術症例の予後検討, 第53回日本肺癌学会総会, Nov. 2012.
457.	Mitsuteru Yoshida, Shoji Sakiyama, 森本雅美, Koichiro Kajiura, Hiroaki Toba, Yasushi Nakagawa, Yukikiyo Kawakami, Hiromitsu Takizawa, Kazuya Kondo and Akira Tangoku : 非連続性多発性腫瘤を呈した悪性胸膜中皮腫の1手術例, 第53回日本肺癌学会総会, Nov. 2012.
458.	田岡真理子, 広瀬敏幸, 住友正幸, 松岡永, 葉久貴司, 米田和夫, 稲山真美, Yukikiyo Kawakami, Yasushi Nakagawa, Hiromitsu Takizawa, Mitsuteru Yoshida, Shoji Sakiyama, Kazuya Kondo and Akira Tangoku : 肺硬化性血管腫の4例, 第53回日本肺癌学会総会, Nov. 2012.
459.	坂本晋一, Koichiro Kajiura, Hiromitsu Takizawa, Yasushi Nakagawa, 森本雅美, Mitsuteru Yoshida, Yukikiyo Kawakami, Shoji Sakiyama and Kazuya Kondo : Erlotinibにて術前導入療法した左肺癌の1手術例, 第53回日本肺癌学会総会, Nov. 2012.
460.	Yukikiyo Kawakami, Shoji Sakiyama, Hiromitsu Takizawa, Kazuya Kondo, Akira Tangoku, 広瀬敏幸, 住友正幸, Takanori Miyoshi, 石倉久嗣, 木村秀, Koichiro Kenzaki, 吉澤潔, 谷田信行, 浜口伸正, 日野弘之 and 福本泰三 : 当院および関連7施設から集計した肺多形癌手術例の臨床的検討, 第53回日本肺癌学会総会, Nov. 2012.
461.	Hiromitsu Takizawa, Kazuya Kondo, 石倉久嗣, 木村秀, 坂本晋一, 宮本佳美, 森本雅美, Koichiro Kajiura, Yasushi Nakagawa, Mitsuteru Yoshida, Yukikiyo Kawakami, Shoji Sakiyama and Akira Tangoku : 非小細胞肺癌完全切除例に対するS-1術後補助化学療法の遺伝子発現解析による効果・予後予測因子の検討, 第53回日本肺癌学会総会, Nov. 2012.
462.	宮本佳美, Hiromitsu Takizawa, Kazuya Kondo, 石倉久嗣, 木村秀, 坂本晋一, 森本雅美, Koichiro Kajiura, Yasushi Nakagawa, Mitsuteru Yoshida, Yukikiyo Kawakami, Shoji Sakiyama and Akira Tangoku : 非小細胞肺癌完全切除例に対するS-1術後補助化学療法の投与完遂性に関する検討, 第53回日本肺癌学会総会, Nov. 2012.
463.	森本雅美, 池田真由美, 古川尊子, Misako Nakagawa, Hirokazu Takechi, Hiromitsu Takizawa, Mitsuteru Yoshida, Yukiko Tadokoro and Akira Tangoku : 第50回日本癌治療学会学術集会, 乳癌胸髄転移に対して緊急放射線照射を行い自宅療養可能となった一例, Oct. 2012.
464.	Hiromitsu Takizawa, Kazuya Kondo, 西野豪志, 森本雅美, Koichiro Kajiura, Hirokazu Takechi, Yasushi Nakagawa, Mitsuteru Yoshida, Yukikiyo Kawakami, Shoji Sakiyama and Akira Tangoku : 肺腺癌術後再発症例に対するEGFR-TKI投与の位置づけに関する検討, 第65回日本胸部外科学会定期学術集会, Oct. 2012.
465.	Koichiro Kajiura, Hiromitsu Takizawa, 森本雅美, 西野豪志, Yoshihito Furukita, Yota Yamamoto, Yasushi Nakagawa, Mitsuteru Yoshida, Yukikiyo Kawakami, Shoji Sakiyama, Kazuya Kondo and Akira Tangoku : 自家蛍光による肺癌胸膜浸潤評価の可能性, 第65回日本胸部外科学会定期学術集会, Oct. 2012.
466.	Koichiro Kajiura, Hiromitsu Takizawa, Hiroaki Toba, 森本雅美, 西野豪志, Yasushi Nakagawa, Mitsuteru Yoshida, Yukikiyo Kawakami, Shoji Sakiyama, Kazuya Kondo and Akira Tangoku : 触知不能肺腫瘍に対する術前細径気管支鏡下コイルマーキングの有用性と安全性, 第65回日本胸部外科学会定期学術集会, Oct. 2012.
467.	Hirokazu Takechi, 森本雅美, 西野豪志, Koichiro Kajiura, Yasushi Nakagawa, Yukikiyo Kawakami, Hiromitsu Takizawa, Mitsuteru Yoshida, Shoji Sakiyama, Kazuya Kondo and Akira Tangoku : 診断に難渋したゲフィチニブ投与中に発生した肺癌術後脳転移の1症例, 第47回日本呼吸器学会中国・四国地方会/第51回日本肺癌学会中国・四国支部会, Jul. 2012.
468.	森本雅美, Misako Nakagawa, Hirokazu Takechi, Yukikiyo Kawakami, Mitsuteru Yoshida, Hiromitsu Takizawa, Koichiro Kenzaki and Akira Tangoku : CTリンパ管造影(CTLG)を用いた術前化学療法(PST)前後のセンチネルリンパ節(SLN)とリンパ路の評価, 第20回日本乳癌学会学術総会, Jun. 2012.
469.	Koichiro Kajiura, Shoji Sakiyama, 森本雅美, Hiroaki Toba, Yasushi Nakagawa, Mitsuteru Yoshida, Yukikiyo Kawakami, Hiromitsu Takizawa, Koichiro Kenzaki, Kazuya Kondo and Akira Tangoku : Lung pointとBf-Naviの気管支自動認識能の検討, 第35回日本呼吸器内視鏡学会学術集会, May 2012.
470.	Shoji Sakiyama, Yukikiyo Kawakami, Koichiro Kajiura, Hiroaki Toba, Yasushi Nakagawa, Mitsuteru Yoshida, Hiromitsu Takizawa, Koichiro Kenzaki, Kazuya Kondo and Akira Tangoku : 当科におけるmulti-modality methodによる気管支鏡教育-特に技能評価方法の実際について-, 第35回日本呼吸器内視鏡学会学術集会, May 2012.
471.	Mitsuteru Yoshida, Kazuya Kondo, Yasushi Nakagawa, 森本雅美, Koichiro Kajiura, Hiroaki Toba, Yukikiyo Kawakami, Hiromitsu Takizawa, Koichiro Kenzaki, Shoji Sakiyama, Akira Tangoku and 横石道寛 : 重症筋無力症患者の術前3D画像による拡大胸腺摘出術後の予後予測の検討, 第29回日本呼吸器外科学会総会, May 2012.
472.	森本雅美, Hiromitsu Takizawa, Koichiro Kajiura, Hiroaki Toba, Yasushi Nakagawa, Mitsuteru Yoshida, Yukikiyo Kawakami, Koichiro Kenzaki, Shoji Sakiyama, Kazuya Kondo and Akira Tangoku : 進行浸潤型胸腺腫に対するCAMP療法の有用性, 第29回日本呼吸器外科学会総会, May 2012.
473.	Kazuya Kondo, 川原有貴, 高井チカ子, 藤田結衣, 大岩由香理, Hiromitsu Takizawa, Yasushi Nakagawa, Koichiro Kajiura, Yukikiyo Kawakami, Mitsuteru Yoshida, Koichiro Kenzaki, Shoji Sakiyama and Akira Tangoku : 肺腺癌における遺伝子不安定性のマーカーとしてのヒストン蛋白γH2AXの発現, 第29回日本呼吸器外科学会総会, May 2012.
474.	Koichiro Kajiura, Shoji Sakiyama, Hiromitsu Takizawa, 森本雅美, Hiroaki Toba, Yasushi Nakagawa, Mitsuteru Yoshida, Yukikiyo Kawakami, Koichiro Kenzaki and Kazuya Kondo : 術前NLR(neutrophil-to-lymphocyte ratio)は非小細胞肺癌の予後予測因子となる, 第29回日本呼吸器外科学会総会, May 2012.
475.	Shoji Sakiyama, Koichiro Kenzaki, Hiroaki Toba, 宇山攻, Koichiro Kajiura, Yasushi Nakagawa, Mitsuteru Yoshida, Yukikiyo Kawakami, Hiromitsu Takizawa, Kazuya Kondo and Akira Tangoku : 肺の再生・修復を目的とした胎生期肺組織移植, 第29回日本呼吸器外科学会総会, May 2012.
476.	Hiromitsu Takizawa, Kazuya Kondo, 松岡永, 森本雅美, Koichiro Kajiura, Hiroaki Toba, Yasushi Nakagawa, Mitsuteru Yoshida, Yukikiyo Kawakami, Koichiro Kenzaki, Shoji Sakiyama and Akira Tangoku : 術前CTリンパ管造影と術中ICG蛍光法による肺癌センチネルリンパ節同定法の確立, 第29回日本呼吸器外科学会総会, May 2012.
477.	Hiromitsu Takizawa, Yasushi Nakagawa, Hirokazu Takechi, 森本雅美, 後藤正和, Misako Nakagawa, Koichiro Kajiura, Yoshihito Furukita, Yota Yamamoto, Mitsuteru Yoshida, Yukikiyo Kawakami and Akira Tangoku : 副甲状腺腺腫摘出術後のテタニー症状出現に関わる因子の検討, 第40回中国四国甲状腺外科研究会, Jan. 2012.
478.	梶浦耕一郎, Shoji Sakiyama, Hiroaki Toba, 森本雅美, 湊拓也, 後藤正和, Yoshihito Furukita, Yota Yamamoto, Yukikiyo Kawakami, Yasushi Nakagawa, Mitsuteru Yoshida, Hiromitsu Takizawa, Koichiro Kenzaki, Kazuya Kondo and Akira Tangoku : 3回にわたる頚部縦隔胸腔ドレナージ術施行し救命しえた降下性壊死性縦隔炎の1例, 第73回日本臨床外科学会総会, Nov. 2011.
479.	Koichiro Kenzaki, Shoji Sakiyama, Hiroaki Toba, 森本雅美, 梶浦耕一郎, 宇山攻, Yasushi Nakagawa, Mitsuteru Yoshida, Yukikiyo Kawakami, Hiromitsu Takizawa, Kazuya Kondo and Akira Tangoku : 突発性と手術後気胸に対するフィブリン糊大量胸腔内注入療法の比較検討, 第73回日本臨床外科学会総会, Nov. 2011.
480.	梶浦耕一郎, Shoji Sakiyama, Hiroaki Toba, 宇山攻, Yasushi Nakagawa, Mitsuteru Yoshida, Hiromitsu Takizawa, Yukikiyo Kawakami, Koichiro Kenzaki, Kazuya Kondo and Akira Tangoku : 胸腺腫摘出後に再生不良性貧血を発症した1例, 第52回日本肺癌学会総会, Nov. 2011.
481.	白石真理子, Kazuya Kondo, 岩佐裕介, 藤田結衣, 大岩由香里, 高井チカ子, Hiromitsu Takizawa, Yasushi Nakagawa, Hiroaki Toba, Yukikiyo Kawakami, 梶浦耕一郎, Koichiro Kenzaki, Shoji Sakiyama and Akira Tangoku : クロム酸塩に暴露したヒト肺癌におけるdsDNAの切断を修復するDNA修復遺伝子の異常の検討, 第52回日本肺癌学会総会, Nov. 2011.
482.	森本雅美, Hiromitsu Takizawa, 梶浦耕一郎, 宇山攻, Hiroaki Toba, Yasushi Nakagawa, Yukikiyo Kawakami, Mitsuteru Yoshida, Koichiro Kenzaki, Shoji Sakiyama, Kazuya Kondo and Akira Tangoku : 肺腺癌手術検体を用いたCycleave-PCR法とPNA-LNA PCR-Clamp法のEGFR遺伝子変異測定結果の比較, 第52回日本肺癌学会総会, Nov. 2011.
483.	佐土原洋平, Hiroaki Toba, Kazuya Kondo, 梶浦耕一郎, Yasushi Nakagawa, Hiromitsu Takizawa, Koichiro Kenzaki, Shoji Sakiyama and Akira Tangoku : 胸腺上皮性腫瘍のFDG-PET/CT所見とHIF-1α，Glut-1，VEGFの発現との関連性, 第52回日本肺癌学会総会, Nov. 2011.
484.	Yukikiyo Kawakami, 梶浦耕一郎, 宇山攻, Hiroaki Toba, Yasushi Nakagawa, Hiromitsu Takizawa, Mitsuteru Yoshida, Koichiro Kenzaki, Shoji Sakiyama, Kazuya Kondo and Akira Tangoku : 肺葉切除術後の残存肺の容積変化と術後呼吸機能についての検討, 第64回日本胸部外科学会定期学術集会, Oct. 2011.
485.	Hiromitsu Takizawa, Hiroaki Toba, 梶浦耕一郎, 森本雅美, 宇山攻, Yasushi Nakagawa, Mitsuteru Yoshida, Yukikiyo Kawakami, Koichiro Kenzaki, Shoji Sakiyama, Kazuya Kondo and Akira Tangoku : 経気管支水溶性造影剤注入によるCTリンパ管造影-区域切除におけるSentinel node navigation surgeryに向けて, 第64回日本胸部外科学会定期学術集会, Oct. 2011.
486.	Hiroaki Toba, Shoji Sakiyama, 梶浦耕一郎, 宇山攻, Yasushi Nakagawa, Yukikiyo Kawakami, Hiromitsu Takizawa, Koichiro Kenzaki, Kazuya Kondo and Akira Tangoku : 自家蛍光気管支鏡(SAFE-3000/AFI)の同時使用経験, 第34回日本呼吸器内視鏡学会学術集会, Jun. 2011.
487.	梶浦耕一郎, Hiroaki Toba, Shoji Sakiyama, 高嶋美佳, 湊拓也, 宇山攻, Hiromitsu Takizawa, Koichiro Kenzaki, Yukikiyo Kawakami, Kazuya Kondo and Akira Tangoku : 当科におけるVBN併用極細径気管支鏡下肺生検の成績, 第34回日本呼吸器内視鏡学会学術集会, Jun. 2011.
488.	Hiromitsu Takizawa, Kazuya Kondo, Hiroaki Toba, 梶浦耕一郎, 高嶋美佳, 湊拓也, 宇山攻, Yasushi Nakagawa, Yukikiyo Kawakami, Koichiro Kenzaki, Shoji Sakiyama and Akira Tangoku : 経気管支水溶性造影剤注入によるCTリンパ管造影-区域切除における術前センチネル, 第111回日本外科学会定期学術集会, May 2011.
489.	Hirokazu Takechi, 池田真由美, 三崎万理子, 高嶋美佳, 兼松美幸, 湊拓也, Misako Nakagawa, 梶浦耕一郎, Yoshihito Furukita, Yota Yamamoto, 宇山攻, Hiroaki Toba, Yasushi Nakagawa, Yukikiyo Kawakami, Hiromitsu Takizawa, Koichiro Kenzaki, Shoji Sakiyama, Kazuya Kondo and Akira Tangoku : 女性外科医の働きやすい現場を目指して, 第111回日本外科学会定期学術集会, May 2011.
490.	兼松美幸, Hiromitsu Takizawa, Kazuya Kondo, 梶浦耕一郎, 宇山攻, Hiroaki Toba, Yasushi Nakagawa, Yukikiyo Kawakami, Koichiro Kenzaki, Shoji Sakiyama and Akira Tangoku : NSCLC完全切除例に対するS-1療法とweekly PTX+CBDCA併用療法の比較検討, 第28回日本呼吸器外科学会総会, May 2011.
491.	Yukikiyo Kawakami, 梶浦耕一郎, 宇山攻, Hiroaki Toba, Yasushi Nakagawa, Hiromitsu Takizawa, Koichiro Kenzaki, Shoji Sakiyama, Kazuya Kondo and Akira Tangoku : 肺葉切除術前後における肺の容積変化についての検討, 第28回日本呼吸器外科学会総会, May 2011.
492.	高嶋美佳, Hiromitsu Takizawa, 梶浦耕一郎, 宇山攻, Hiroaki Toba, Yasushi Nakagawa, Yukikiyo Kawakami, Koichiro Kenzaki, Shoji Sakiyama, Kazuya Kondo and Akira Tangoku : 肺癌との鑑別が困難であった結節性リンパ組織過形成の2切除例, 第28回日本呼吸器外科学会総会, May 2011.
493.	梶浦耕一郎, 高嶋美佳, Hiroaki Toba, Hiromitsu Takizawa, Koichiro Kenzaki, Yasushi Nakagawa, Yukikiyo Kawakami, 宇山攻, Shoji Sakiyama, Kazuya Kondo and Akira Tangoku : 肺癌手術時の胸腔内洗浄細胞診陽性症例の検討, 第28回日本呼吸器外科学会総会, May 2011.
494.	Koichiro Kenzaki, Shoji Sakiyama, Hiroaki Toba, 梶浦耕一郎, 宇山攻, Yasushi Nakagawa, Yukikiyo Kawakami, Hiromitsu Takizawa, Kazuya Kondo and Akira Tangoku : 気胸に対するフィブリン糊大量胸腔内注入療法の検討, 第28回日本呼吸器外科学会総会, May 2011.
495.	Hiroaki Toba, Shoji Sakiyama, 高嶋美佳, 梶浦耕一郎, 宇山攻, Yasushi Nakagawa, Yukikiyo Kawakami, Hiromitsu Takizawa, Koichiro Kenzaki, Kazuya Kondo and Akira Tangoku : 肺癌術後のフォローアップにPET/CTは有用か, 第28回日本呼吸器外科学会総会, May 2011.
496.	Kazuya Kondo, 名村寿章, 藤田結衣, 高井チカ子, 大岩由香理, Hiromitsu Takizawa, Yasushi Nakagawa, Hiroaki Toba, 梶浦耕一郎, Yukikiyo Kawakami, Koichiro Kenzaki, Shoji Sakiyama and Akira Tangoku : 胸腺上皮性腫瘍におけるDNA修復遺伝子MGMTのDNAメチル化と蛋白発現, 第28回日本呼吸器外科学会総会, May 2011.
497.	Hiromitsu Takizawa, Kazuya Kondo, Hiroaki Toba, 梶浦耕一郎, 宇山攻, Yasushi Nakagawa, Yukikiyo Kawakami, Koichiro Kenzaki, Shoji Sakiyama and Akira Tangoku : 呼吸器領域におけるレーザー診断・治療の現況と展望, 第31回日本レーザー医学会総会, Nov. 2010.
498.	藤田結衣, Kazuya Kondo, Hamed Ali Abdellah Khalil, 名村寿章, 仙波義貴, Hiromitsu Takizawa, Yasushi Nakagawa, Hiroaki Toba, Koichiro Kenzaki, Shoji Sakiyama and Akira Tangoku : クロム工場従事者におけるlung cancer susceptibilityの解析, 第51回日本肺癌学会総会, Nov. 2010.
499.	Kazuya Kondo, Hamed Ali Abdellah Khalil, Hiromitsu Takizawa, Yasushi Nakagawa, Hiroaki Toba, Koichiro Kenzaki, Shoji Sakiyama and Akira Tangoku : クロム酸塩に暴露した労働者に発生した肺癌における癌関連遺伝子の異常, 第51回日本肺癌学会総会, Nov. 2010.
500.	Hiroaki Toba, Shoji Sakiyama, Koichiro Kenzaki, Yukikiyo Kawakami, Hiromitsu Takizawa, Kazuya Kondo and Akira Tangoku : 胎仔肺組織移植により移植したグラフト内でのTTF-1発現の検討, 第63回日本胸部外科学会定期学術集会, Oct. 2010.
501.	Hiromitsu Takizawa, Khalil Harmed Abdellah, Kazuya Kondo, 松岡永, Hiroaki Toba, Yasushi Nakagawa, Koichiro Kenzaki, Shoji Sakiyama, Souji Kakiuchi, Saburo Sone and Akira Tangoku : 5-アミノレブリン酸を用いた胸膜悪性腫瘍の蛍光診断, 第63回日本胸部外科学会定期学術集会, Oct. 2010.
502.	Kazuya Kondo, ハーメド・カーリル・アリアブデラ, 名村寿章, 仙波義貴, Hiromitsu Takizawa, Yasushi Nakagawa, Hiroaki Toba, Koichiro Kenzaki, Shoji Sakiyama and Akira Tangoku : クロム工場労働者の肺がんにおける癌抑制遺伝子のDNAメチル化, 第69回日本癌学会学術総会, Sep. 2010.
503.	Hiromitsu Takizawa, Khalil Harmed Abdellah, Kazuya Kondo, 松岡永, Hiroaki Toba, Yasushi Nakagawa, Koichiro Kenzaki, Shoji Sakiyama, Souji Kakiuchi, Saburo Sone and Akira Tangoku : 5-アミノレブリン酸を用いた胸膜悪性腫瘍の蛍光診断, 第20回日本光線力学学会学術講演会, Jun. 2010.
504.	河南真吾, Koichiro Kenzaki, Hiroaki Toba, 森本雅美, Yasushi Nakagawa, Hiromitsu Takizawa, Shoji Sakiyama, Kazuya Kondo and Akira Tangoku : 巨大気腫性肺嚢胞に対して嚢胞内ドレナージ後に気管支塞栓術+フィブリン糊嚢胞内注入により治療した1例, 第33回日本呼吸器内視鏡学会学術集会, Jun. 2010.
505.	Hiroaki Toba, Shoji Sakiyama, 兼松美幸, Hiromitsu Takizawa, Koichiro Kenzaki, Kazuya Kondo and Akira Tangoku : CT所見から見た小型末梢肺病変に対する極細径気管支鏡を用いたCTガイド下肺生検の適応の再構築, 第33回日本呼吸器内視鏡学会学術集会, Jun. 2010.
506.	兼松美幸, Hiroaki Toba, Shoji Sakiyama, Takanori Miyoshi, Hiromitsu Takizawa, Koichiro Kenzaki, Kazuya Kondo and Akira Tangoku : 小型末梢肺病変に対するVBN併用下CTガイド下気管支鏡下コイルマーキング, 第33回日本呼吸器内視鏡学会学術集会, Jun. 2010.
507.	Abdellah Hamed, Hiroaki Toba, Shoji Sakiyama, 山本良, Hiromitsu Takizawa, Koichiro Kenzaki, Kazuya Kondo and Akira Tangoku : Holter ECG Monitoring of Sympathovagal Fluctuations During Bronchoscopy, 第33回日本呼吸器内視鏡学会学術集会, Jun. 2010.
508.	Shoji Sakiyama, Hiroaki Toba, Yasushi Nakagawa, Hiromitsu Takizawa, Koichiro Kenzaki, Kazuya Kondo and Akira Tangoku : 当科におけるmulti-modality methodを用いた気管支鏡検査の教育方法, 第33回日本呼吸器内視鏡学会学術集会, Jun. 2010.
509.	森本雅美, Hiroaki Toba, Shoji Sakiyama, 兼松美幸, 藤原聡史, 井上聖也, Yasushi Nakagawa, Hiromitsu Takizawa, Koichiro Kenzaki, Kazuya Kondo and Akira Tangoku : 多中心性に発生したと考えられた同時性多発胸腺腫の1例, 第27回日本呼吸器外科学会総会, May 2010.
510.	兼松美幸, 高嶋美佳, 森本雅美, 井上聖也, 藤原聡史, Hiroaki Toba, Hiromitsu Takizawa, Koichiro Kenzaki, Shoji Sakiyama, Kazuya Kondo and Akira Tangoku : 非小細胞肺癌に対する術後補助療法としてのweekly paclitaxel+carboplatin(wTJ)併用療法の検討, 第27回日本呼吸器外科学会総会, May 2010.
511.	川田祐子, Hiromitsu Takizawa, Hiroaki Toba, Yasushi Nakagawa, Koichiro Kenzaki, Shoji Sakiyama, Kazuya Kondo, Mitsuo Shimada and Akira Tangoku : 先天性心膜欠損を合併した肺嚢胞症の一切除例, 第27回日本呼吸器外科学会総会, May 2010.
512.	高嶋美佳, Hiroaki Toba, Koichiro Kenzaki, 森本雅美, 兼松美幸, Yasushi Nakagawa, Hiromitsu Takizawa, Shoji Sakiyama, Kazuya Kondo and Akira Tangoku : 当科における肺動静脈瘻手術症例の臨床的検討, 第27回日本呼吸器外科学会総会, May 2010.
513.	Hiroaki Toba, Kazuya Kondo, Hiromitsu Takizawa, 高嶋美佳, 森本雅美, 兼松美幸, Yasushi Nakagawa, Koichiro Kenzaki, Shoji Sakiyama and Akira Tangoku : 肺癌術後再発症例の検討, 第27回日本呼吸器外科学会総会, May 2010.
514.	Hiromitsu Takizawa, 高嶋美佳, 兼松美幸, 森本雅美, 藤原聡史, 井上聖也, Hiroaki Toba, Yasushi Nakagawa, Koichiro Kenzaki and Shoji Sakiyama : Sublobar resection後の自動縫合ラインに形成される軟部陰影の検討, 第27回日本呼吸器外科学会総会, May 2010.
515.	澤田徹, Hiromitsu Takizawa, Hiroaki Toba, Yasushi Nakagawa, Koichiro Kenzaki, Shoji Sakiyama, Kazuya Kondo and Akira Tangoku : CT画像を用いた右上葉切除術前および術後の肺容積の変化についての検討, 第27回日本呼吸器外科学会総会, May 2010.
516.	Koichiro Kenzaki, Hitoshi Ikushima, Kazuya Kondo, Hiroaki Toba, Yasushi Nakagawa, Hiromitsu Takizawa, Shoji Sakiyama and Akira Tangoku : 原発性肺癌Ⅰ期における消極的肺部分切除と定位放射線治療との比較, 第27回日本呼吸器外科学会総会, May 2010.
517.	Shoji Sakiyama, Koichiro Kenzaki, Hiroaki Toba, Khasag Narmisheekh, 宇山攻, Yasushi Nakagawa, Hiromitsu Takizawa, Kazuya Kondo and Akira Tangoku : 豚を用いた胎生期肺組織移植の実験的検討-ラットで得られた知見との比較を含めて-, 第27回日本呼吸器外科学会総会, May 2010.
518.	Kazuya Kondo, 張真弓, 田所由紀子, 仙波義貴, Yasushi Nakagawa, Hiromitsu Takizawa, Hiroaki Toba, Koichiro Kenzaki, Shoji Sakiyama and Akira Tangoku : 胸腺上皮性腫瘍の発生におけるDNA修復遺伝子MGMTの関連性, 第27回日本呼吸器外科学会総会, May 2010.
519.	森本雅美, 吉良美砂子, 兼松美幸, 井上聖也, 藤原聡史, Yoshihito Furukita, Yota Yamamoto, Yasushi Nakagawa, Hiromitsu Takizawa and Akira Tangoku : 甲状腺未分化癌に対する経口フッ化ピリミジン系抗癌剤による補助療法の可能性, 第110回日本外科学会定期学術集会, Apr. 2010.
520.	Koichiro Kenzaki, Shoji Sakiyama, 宇山攻, Hiroaki Toba, Yasushi Nakagawa, Hiromitsu Takizawa, Kazuya Kondo and Akira Tangoku : Sex-mismatchを用いたラット胎仔肺移植モデルのドナー細胞の組織学的検討, 第110回日本外科学会定期学術集会, Apr. 2010.
521.	Yasushi Nakagawa, Kazuya Kondo, Hiroaki Toba, Hiromitsu Takizawa, Koichiro Kenzaki, Shoji Sakiyama and Akira Tangoku : 胸腺癌44例の検討, 第110回日本外科学会定期学術集会, Apr. 2010.
522.	Hiromitsu Takizawa, Kazuya Kondo, Abdellah Khalil Hamed, 松岡永, Hiroaki Toba, Yasushi Nakagawa, Koichiro Kenzaki, Shoji Sakiyama and Akira Tangoku : 光感受性物質を用いた胸膜悪性腫瘍の蛍光診断-SCIDマウスヒト肺癌胸膜播種モデルを用いた実験-, 第110回日本外科学会定期学術集会, Apr. 2010.
523.	Shoji Sakiyama, Koichiro Kenzaki, Hiroaki Toba, Khasag Narmisheekh, 宇山攻, Yasushi Nakagawa, Hiromitsu Takizawa, Kazuya Kondo and Akira Tangoku : 豚を用いた胎生期肺組織移植の実験的検討, 第110回日本外科学会定期学術集会, Apr. 2010.
524.	Narmisheekh Khasag, Shoji Sakiyama, Hiroaki Toba, Yasushi Nakagawa, Hiromitsu Takizawa, Koichiro Kenzaki, Kazuya Kondo and Akira Tangoku : 肺癌手術における呼気中一酸化および二酸化炭素モニタリング, 第110回日本外科学会定期学術集会, Apr. 2010.
525.	宇山攻, Shoji Sakiyama, 松岡永, Hiroaki Toba, Hiromitsu Takizawa, Koichiro Kenzaki, Kazuya Kondo and Akira Tangoku : 非結核性抗酸菌症手術症例の検討, 第110回日本外科学会定期学術集会, Apr. 2010.

Et cetera, Workshop:

1.	Hiromitsu Takizawa : 《教授就任記念講演》肺癌外科治療の課題解決を目指して, 第268回徳島医学会学術集会, Mar. 2024.
2.	Masakazu Goto, Seiya Inoue, Satoshi Fujiwara, 髙杉遥, 細川暉雄, Sawaka Yukishige, Taihei Takeuchi, Tomohiro Inui, Hiroyuki Sumitomo, Naoki Miyamoto, Shin-ichi Sakamoto, Souichiro Sasa, Atsushi Morishita, Mariko Aoyama, Hiroaki Inoue, Naoya Kawakita, Hiroaki Toba and Hiromitsu Takizawa : 当院における腹臥位胸腔鏡下食道亜全摘術の術後短期成績について, 第36回四国内視鏡外科研究会, Mar. 2024.
3.	Masakazu Goto, Seiya Inoue, Satoshi Fujiwara, 髙杉遥, 細川暉雄, 竹内大平, Hiroyuki Sumitomo, Atsushi Morishita, Mariko Aoyama, Hiroaki Toba and Hiromitsu Takizawa : 腹臥位胸腔鏡下食道亜全摘術の術後短期成績について, 第44回四国食道疾患研究会学術講演会, Feb. 2024.
4.	Satoshi Fujiwara, Masakazu Goto, Seiya Inoue, 髙杉遥, 細川暉雄, 竹内大平, Hiroyuki Sumitomo, Atsushi Morishita, Mariko Aoyama, Hiroaki Toba and Hiromitsu Takizawa : 食道癌根治術後の再発症例の検討, 第44回四国食道疾患研究会学術講演会, Feb. 2024.
5.	Seiya Inoue, Masakazu Goto, Satoshi Fujiwara, 髙杉遥, 細川暉雄, 竹内大平, Hiroyuki Sumitomo, Atsushi Morishita, Mariko Aoyama, Hiroaki Toba and Hiromitsu Takizawa : 吻合部トラブル回避のわれわれの工夫 ∼吻合法の比較検討∼, 第44回四国食道疾患研究会学術講演会, Feb. 2024.
6.	髙杉遥, Masakazu Goto, Seiya Inoue, Satoshi Fujiwara, 細川暉雄, 竹内大平, Hiroyuki Sumitomo, Atsushi Morishita, Mariko Aoyama, Hiroaki Toba and Hiromitsu Takizawa : 食道胃接合部癌における術式別短期成績の比較, 第44回四国食道疾患研究会学術講演会, Feb. 2024.
7.	細川暉雄, Mariko Aoyama, 竹内大平, Tomohiro Inui, 髙杉遥, Shin-ichi Sakamoto, Hiroyuki Sumitomo, Naoki Miyamoto, Atsushi Morishita, Seiya Inoue, Satoshi Fujiwara, Masakazu Goto, Hiroaki Toba and Hiromitsu Takizawa : レンバチニブ内服中に間質性肺炎をきたした甲状腺低分化癌の一例, 第52回中国四国甲状腺外科研究会, Feb. 2024.
8.	Shin-ichi Sakamoto, Mariko Aoyama, 細川暉雄, 竹内大平, 髙杉遥, Naoki Miyamoto, Atsushi Morishita, Seiya Inoue, Satoshi Fujiwara, Masakazu Goto, Hiroaki Toba and Hiromitsu Takizawa : Dynamic CTが局在診断に有用であった原発性副甲状腺機能亢進症の2例, 第52回中国四国甲状腺外科研究会, Feb. 2024.
9.	Mariko Aoyama, 細川暉雄, 竹内大平, 髙杉遥, Shin-ichi Sakamoto, Naoki Miyamoto, Atsushi Morishita, Seiya Inoue, Satoshi Fujiwara, Masakazu Goto, Hiroaki Toba, Yoshimi Bando, Hisanori Uehara and Hiromitsu Takizawa : 穿刺吸引細胞への免疫染色併用が術前診断に有用であった2症例, 第52回中国四国甲状腺外科研究会, Feb. 2024.
10.	竹内大平, Naoya Kawakita, 細川暉雄, Hiroyuki Sumitomo, Naoki Miyamoto, Shin-ichi Sakamoto, Atsushi Morishita, Hiroaki Toba, Kazuya Kondo and Hiromitsu Takizawa : 左B1+2転位気管支を伴い肺癌に対して胸腔鏡下肺区域切除術を施行した1例, 第32回日本呼吸器内視鏡学会中国四国支部会, Dec. 2023.
11.	Atsushi Morishita, Naoya Kawakita, 細川暉雄, 竹内大平, Hiroyuki Sumitomo, Naoki Miyamoto, Shin-ichi Sakamoto, Hiroaki Toba, Kazuya Kondo and Hiromitsu Takizawa : Cone-beam CT由来Augmented Fluoroscopyを用いた気管支鏡下生検, 第32回日本呼吸器内視鏡学会中国四国支部会, Dec. 2023.
12.	Hiroyuki Sumitomo, Hiroaki Toba, 細川暉雄, 竹内大平, 髙杉遥, Shin-ichi Sakamoto, Naoki Miyamoto, Atsushi Morishita, Naoya Kawakita, Kazuya Kondo and Hiromitsu Takizawa : 小型末梢肺病変に対する，Cone-beam CTを用いた気管支鏡下コイルマーキング, 第32回日本呼吸器内視鏡学会中国四国支部会, Dec. 2023.
13.	Hiromitsu Takizawa : チームで肺癌手術のレベルアップを, 第23回高知内視鏡外科フォーラム, Aug. 2023.
14.	竹内大平, Hiromitsu Takizawa, 井﨑富由実, 住友弘幸, Naoki Miyamoto, Shin-ichi Sakamoto, Mika Takashima, Naoya Kawakita and Hiroaki Toba : ロボット支援手術が有用であったIgG4関連後縦隔腫瘍の1例, 第35回四国内視鏡外科研究会, Feb. 2023.
15.	Satoshi Fujiwara, 井﨑富由実, 竹内大平, 住友弘幸, Seiya Inoue, Masakazu Goto and Hiromitsu Takizawa : 食道癌手術における胃管作成に対する術式の検討, 第35回四国内視鏡外科研究会, Feb. 2023.
16.	竹内大平, Seiya Inoue, 井﨑富由実, Hiroyuki Sumitomo, Satoshi Fujiwara, Masakazu Goto, Hiroaki Toba and Hiromitsu Takizawa : 食道癌根治術後に急激な経過を辿った緑膿菌肺炎の1例, 第6回徳島外科医会, Feb. 2023.
17.	Mika Takashima, 井﨑富由実, 竹内大平, Shin-ichi Sakamoto, Hiroyuki Sumitomo, Naoki Miyamoto, Naoya Kawakita, Hiroaki Toba, Yukikiyo Kawakami, Kazuya Kondo and Hiromitsu Takizawa : 左腕頭静脈合併切除を伴う拡大胸腺摘出術後に静脈内に血栓形成を認めた1例, 第6回徳島外科医会, Feb. 2023.
18.	三崎万理子, 井﨑富由実, 竹内大平, Shin-ichi Sakamoto, Naoki Miyamoto, Seiya Inoue, Naoya Kawakita, Satoshi Fujiwara, Masakazu Goto, Hiroaki Toba and Hiromitsu Takizawa : レンバチニブ投与後に切除し得た局所進行甲状腺乳頭癌の1例, 第6回徳島外科医会, Feb. 2023.
19.	住友弘幸, Masakazu Goto, Seiya Inoue, Satoshi Fujiwara, 井﨑富由実, 行重佐和香, 竹内大平, Tomohiro Inui, Shin-ichi Sakamoto, Naoki Miyamoto, Souichiro Sasa, 三崎万理子, Hiroaki Inoue, Mika Takashima, Naoya Kawakita, Kazumasa Okumura, Hiroaki Toba and Hiromitsu Takizawa : 食道癌術後，再建胃管穿孔による右膿胸を生じた1例, 第6回徳島外科医会, Feb. 2023.
20.	Satoshi Fujiwara, 井﨑富由実, 行重佐和香, 竹内大平, Hiroyuki Sumitomo, Seiya Inoue, Masakazu Goto, Hiroaki Toba and Hiromitsu Takizawa : 食道癌手術における胃管作成に対する術式の検討, 第43回四国食道疾患研究会学術講演会, Jan. 2023.
21.	Seiya Inoue, 井﨑富由実, 行重佐和香, 竹内大平, Hiroyuki Sumitomo, Satoshi Fujiwara, Masakazu Goto, Hiroaki Toba and Hiromitsu Takizawa : 術後補助療法としてのNivolumabの可能性, 第43回四国食道疾患研究会学術講演会, Jan. 2023.
22.	井﨑富由実, Masakazu Goto, 行重佐和香, 竹内大平, Tomohiro Inui, Hiroyuki Sumitomo, Satoshi Fujiwara, Seiya Inoue, Hiroaki Toba and Hiromitsu Takizawa : 食道蠕動運動障害を伴う横隔膜上食道憩室に対して腹腔鏡下手術を施行した1例, 第43回四国食道疾患研究会学術講演会, Jan. 2023.
23.	竹内大平, Seiya Inoue, 井﨑富由実, 行重佐和香, Hiroyuki Sumitomo, Satoshi Fujiwara, Masakazu Goto, Hiroaki Toba and Hiromitsu Takizawa : 食道癌根治術後に急激な経過を辿った緑膿菌肺炎の一例, 第43回四国食道疾患研究会学術講演会, Jan. 2023.
24.	Hiromitsu Takizawa : がんにかかるリスクを減らす生活習慣, 徳島ピンクリボン集会2022, Oct. 2022.
25.	井﨑富由実, Hiroaki Inoue, Tomohiro Inui, Souichiro Sasa, Mariko Aoyama, Naoki Miyamoto, Kazumasa Okumura, Hiroaki Toba, Masakazu Goto, 住田智志, Yoshimi Bando and Hiromitsu Takizawa : 巨大石灰化を認めた骨・軟骨化生を伴う乳癌の1例, 第19回日本乳癌学会中国四国地方会, Sep. 2022.
26.	青山理央, Souichiro Sasa, Tomohiro Inui, Mariko Aoyama, Kazumasa Okumura, Hiroaki Inoue, Hiroaki Toba, Masakazu Goto, Takeshi Oya and Hiromitsu Takizawa : 乳腺腺様嚢胞癌の一例, 第19回日本乳癌学会中国四国地方会, Sep. 2022.
27.	Mika Takashima, Hiroaki Toba, Shinichi Sakamoto, Naoki Miyamoto, Seiya Inoue, Naoya Kawakita, Satoshi Fujiwara, Masakazu Goto, Takahiro Yoshida, Jun-ichi Seike, Yukikiyo Kawakami, Kazuya Kondo and Hiromitsu Takizawa : 進行食道癌による気道のEmergencyに対する気道ステント留置例の検討, 第5回徳島外科医会, Feb. 2022.
28.	Mariko Aoyama, Tomohiro Inui, Shinichi Sakamoto, Naoki Miyamoto, Seiya Inoue, Naoya Kawakita, Satoshi Fujiwara, Masakazu Goto, Hiroaki Toba and Hiromitsu Takizawa : 当院でのBasedow病に対する内視鏡下甲状腺手術についての治療成績, 第5回徳島外科医会, Feb. 2022.
29.	Tomohiro Inui, Hiroaki Inoue, Soichiroh Sasa, Mariko Aoyama, Kazumasa Okumura, Naoki Miyamoto, Hiroaki Toba, Takahiro Yoshida and Hiromitsu Takizawa : アベマシクリブ投与中に重篤な間質性肺炎を来したが救命しえた1例, 第5回徳島外科医会, Feb. 2022.
30.	Seiya Inoue, Takahiro Yoshida, Masakazu Goto, Satoshi Fujiwara, Tomohiro Inui, Shinichi Sakamoto, Naoki Miyamoto, Mariko Aoyama, Hiroaki Toba, Akira Tangoku and Hiromitsu Takizawa : 安全な食道再建のわれわれの工夫, 第5回徳島外科医会, Feb. 2022.
31.	Seiya Inoue, Takahiro Yoshida, Masakazu Goto, Satoshi Fujiwara, Tomohiro Inui, Shinichi Sakamoto, Naoki Miyamoto, Mariko Aoyama, Akira Tangoku, Hiroaki Toba and Hiromitsu Takizawa : 食道切除後再建術における最近の取り組み-ICG血流評価法とCollard変法の有用性-, 第42回四国食道疾患研究会(WEB開催), Feb. 2022.
32.	Satoshi Fujiwara, Takahiro Yoshida, Masakazu Goto, Seiya Inoue, Tomohiro Inui, Shinichi Sakamoto, Naoki Miyamoto, Mariko Aoyama, Akira Tangoku, Hiroaki Toba and Hiromitsu Takizawa : 肺癌を合併した食道癌に対し，一期的手術を施行した3例の検討, 第42回四国食道疾患研究会(WEB開催), Feb. 2022.
33.	Mariko Aoyama, Tomohiro Inui, Shinichi Sakamoto, Naoki Miyamoto, Seiya Inoue, Naoya Kawakita, Satoshi Fujiwara, Masakazu Goto, Hiroaki Toba and Hiromitsu Takizawa : 当院でのBasedow病に対する内視鏡下甲状腺手術についての治療成績, 第50回中国四国甲状腺外科研究会, Feb. 2022.
34.	庄野隆志, Mariko Aoyama, 南城和正, 山本清成, Hidenori Maki, Tomohiro Inui, Shinichi Sakamoto, Tomoko Kobayashi, Shingen Nakamura, Hiromitsu Takizawa and Akira Tangoku : アブスコパル効果を示した甲状腺原発形質細胞腫の1例, 第49回中国四国甲状腺外科研究会(ハイブリッド開催), Feb. 2021.
35.	Mariko Aoyama, Hiromitsu Takizawa, 庄野隆志, 南城和正, Hidenori Maki, 山本清成, INUI Tomohiro, Naoki Miyamoto, Shinichi Sakamoto and Akira Tangoku : 低用量レンバチニブで長期PRを維持できている再発甲状腺乳頭癌の1例, 第49回中国四国甲状腺外科研究会(ハイブリッド開催), Feb. 2021.
36.	Naoki Miyamoto, Mitsuteru Yoshida, Kenji Otsuka, Mika Takashima, Daisuke Matsumoto, Naoya Kawakita, Mitsuhiro Tsuboi, Hiroaki Toba, Yukikiyo Kawakami, Kazuya Kondo, Yasuhiko Nishioka, Hiromitsu Takizawa and Akira Tangoku : 胸腔鏡下に確定診断を得たCalcifying fibrous tumorの1例, 第4回徳島外科医会, Feb. 2021.
37.	Shinichi Sakamoto, Hiromitsu Takizawa, 山本清成, Naoki Miyamoto, Mika Takashima, Daisuke Matsumoto, Naoya Kawakita, Hiroaki Toba, Yukikiyo Kawakami, Mitsuteru Yoshida, Kazuya Kondo and Akira Tangoku : 左B1+2転位気管支とV1+2の走行異常を認める左下葉肺癌の一切除例, 第4回徳島外科医会, Feb. 2021.
38.	庄野隆志, Hiromitsu Takizawa, 南城和正, 山本清成, Naoki Miyamoto, Shinichi Sakamoto, Mika Takashima, Daisuke Matsumoto, Naoya Kawakita, Mitsuteru Yoshida, Hiroaki Toba, Yukikiyo Kawakami, Kazuya Kondo and Akira Tangoku : 網膜芽細胞腫治療後に縦隔鏡に発生した平滑筋肉腫の一例, 第4回徳島外科医会, Feb. 2021.
39.	INUI Tomohiro, Hiroaki Inoue, Soichiroh Sasa, Mariko Aoyama, Kazumasa Okumura, Hiroaki Toba, Hiromitsu Takizawa and Akira Tangoku : トラスツズマブ+ペルツズマブ投与にて重度のinfusion reactionを認めたが再投与可能であった1例, 第4回徳島外科医会, Feb. 2021.
40.	山本清成, Mariko Aoyama, Hiromitsu Takizawa, 南城和正, 庄野隆志, Hidenori Maki and Akira Tangoku : 右心房転移をきたした甲状腺未分化癌の1例, 第4回徳島外科医会, Feb. 2021.
41.	山本清成, Takeshi Nishino, 庄野隆志, 南城和正, Hidenori Maki, 宮本直輝, Mika Takashima, Daisuke Matsumoto, Naoya Kawakita, Seiya Inoue, Masakazu Goto, Takahiro Yoshida, Hiroaki Toba, Mitsuteru Yoshida, Hiromitsu Takizawa and Akira Tangoku : 気管分岐部狭窄を伴う進行食道癌に対する集学的治療の経験, 第261回徳島医学会学術集会(Web配信), Aug. 2020.
42.	Hidenori Maki, Hiromitsu Takizawa, 庄野隆志, 南城和正, 山本清成, Naoki Miyamoto, SAKAMOTO Shinichi, Daisuke Matsumoto, Mika Takashima, Naoya Kawakita, Hiroaki Toba, Mitsuteru Yoshida, Yukikiyo Kawakami, Kazuya Kondo and Akira Tangoku : 微小肺病変に対して術中Cone-beam CT併用気管支鏡下コイルマーキングが有用であった1例, 第261回徳島医学会学術集会(Web配信), Aug. 2020.
43.	Kazumasa Nanjo, Naoya Kawakita, Mitsuteru Yoshida, 庄野隆志, 山本清成, Hidenori Maki, Shinichi Sakamoto, Naoki Miyamoto, Mika Takashima, Daisuke Matsumoto, Hiroaki Toba, Yukikiyo Kawakami, Hiromitsu Takizawa, Kazuya Kondo and Akira Tangoku : 肺アミロイドーシスを伴った上皮内肺腺癌の1例, 第261回徳島医学会学術集会(Web配信), Aug. 2020.
44.	Hiroaki Toba, Hiromitsu Takizawa, 庄野隆志, 南城和正, 山本清成, Hidenori Maki, Tomohiro Inui, Shinichi Sakamoto, Naoki Miyamoto, Soichiroh Sasa, Mariko Aoyama, Hiroaki Inoue, Mika Takashima, Daisuke Matsumoto, Seiya Inoue, Naoya Kawakita, Masakazu Goto, Takeshi Nishino, Kazumasa Okumura, Takahiro Yoshida, Yukikiyo Kawakami, Mitsuteru Yoshida, Kazuya Kondo and Akira Tangoku : より良いがんの地域連携体制構築のための取り組み, 第261回徳島医学会学術集会(Web配信), Aug. 2020.
45.	Kai Mizobuchi, 青山万理子, Hiromitsu Takizawa, 竹原恵美, Naoya Kawakita, Mitsuhiro Tsuboi and Akira Tangoku : 巨大甲状腺腫によって高度の気管狭窄を生じた1症例, 第3回徳島外科医会, Feb. 2020.
46.	竹原恵美, Mitsuhiro Tsuboi, Hiromitsu Takizawa, Kai Mizobuchi, 宮本直輝, 高嶋美佳, 松本大資, Naoya Kawakita, Hiroaki Toba, Mitsuteru Yoshida, Yukikiyo Kawakami and Kazuya Kondo : 呼吸器外科領域における後期研修医修練，大学2年間での経験と理想について, 第3回徳島外科医会, Feb. 2020.
47.	Hiromitsu Takizawa, Hiroaki Toba, Daisuke Matsumoto, Mika Takashima, 竹原恵美, Naoki Miyamoto, Naoya Kawakita, Mitsuhiro Tsuboi, Mitsuteru Yoshida, Yukikiyo Kawakami, Kazuya Kondo and Akira Tangoku : チームで行う3Dモデルを用いたロボット支援胸腔鏡下肺葉切除のシミュレーション, 第34回四国内視鏡外科研究会, Feb. 2020.
48.	青山万理子, Hiromitsu Takizawa, Kai Mizobuchi, 竹原恵美, Mitsuhiro Tsuboi and Akira Tangoku : 自家蛍光による副甲状腺の同定-励起光による自家蛍光の変化に注目して-, 第48回中国四国甲状腺外科研究会, Feb. 2020.
49.	Mitsuhiro Tsuboi, 青山万理子, Hiromitsu Takizawa, Kai Mizobuchi, 竹原恵美 and Akira Tangoku : 甲状腺がん再発症例の検討, 第48回中国四国甲状腺外科研究会, Feb. 2020.
50.	Kai Mizobuchi, Mitsuhiro Tsuboi, 竹原恵美, 宮本直輝, 青山万理子, Hiromitsu Takizawa and Akira Tangoku : 上肢の知覚障害で発症した甲状腺乳頭癌脳転移の1例, 第48回中国四国甲状腺外科研究会, Feb. 2020.
51.	竹原恵美, 青山万理子, Hiromitsu Takizawa, Kai Mizobuchi, Naoya Kawakita, Mitsuhiro Tsuboi and Akira Tangoku : 巨大甲状腺腫によって高度の気管狭窄を生じた1症例, 第48回中国四国甲状腺外科研究会, Feb. 2020.
52.	Kiyoe Kurahashi, 青山万里子, Hiromitsu Takizawa, 遠藤ふうり, 三井由香里, 桝田志保, Sumiko Yoshida, 明比祐子, Itsuro Endo, Ken-ichi Aihara, Masahiro Abe and Seiji Fukumoto : 薬物治療に抵抗性で，日和見感染も合併したバセドウ病の一例, 第29回臨床内分泌代謝Update in Kochi, Nov. 2019.
53.	Daisuke Matsumoto, Hiromitsu Takizawa, 鈴木恵美, 山田亮, Mika Takashima, Naoya Kawakita, Toru Sawada, Mitsuhiro Tsuboi, Hiroaki Toba, Yukikiyo Kawakami, Mitsuteru Yoshida, Kazuya Kondo and Akira Tangoku : 触知困難小型肺病変をコイルと色素を用いたマーキング法で切除した1例, 第33回四国内視鏡外科研究会, Feb. 2019.
54.	Mitsuhiro Tsuboi, 青山万理子, Hiromitsu Takizawa and Akira Tangoku : 内視鏡下甲状腺外科手術における反回神経，上咽頭神経外枝の温存, 第47回中国四国甲状腺外科研究会, Feb. 2019.
55.	青山万理子, Hiromitsu Takizawa, Mitsuhiro Tsuboi and Akira Tangoku : 当科で経験した三次性副甲状腺機能亢進症の2症例, 第47回中国四国甲状腺外科研究会, Feb. 2019.
56.	鈴木恵美, Mika Takashima, Hiroaki Toba, Daisuke Matsumoto, Masami Morimoto, Naoya Kawakita, Toru Sawada, Mitsuhiro Tsuboi, Hirokazu Takechi, Yukikiyo Kawakami, Hiromitsu Takizawa, Mitsuteru Yoshida, Kazuya Kondo and Akira Tangoku : 放射線皮膚潰瘍・胸骨骨髄炎に対し広汎骨性胸郭切除を行った乳癌再発の1例, 第2回徳島外科医会, Feb. 2019.
57.	山田亮, Daisuke Matsumoto, Mika Takashima, Toru Sawada, Naoya Kawakita, Mitsuhiro Tsuboi, Hiroaki Toba, Yukikiyo Kawakami, Mitsuteru Yoshida, Hiromitsu Takizawa, Kazuya Kondo and Akira Tangoku : 術前化学放射線療法後Transmanubrial approach(TMA)で完全切除が可能であったPancoast腫瘍の1例, 第2回徳島外科医会, Feb. 2019.
58.	Mitsuteru Yoshida, Kazuya Kondo, 湯浅将生, 池光大貴, Toru Sawada, 鈴木恵美, 山田亮, Mika Takashima, Daisuke Matsumoto, Naoya Kawakita, Mitsuhiro Tsuboi, Hiroaki Toba, Yukikiyo Kawakami, Hiromitsu Takizawa and Akira Tangoku : 拡大胸腺摘出術における術式の比較検討, 第38回日本胸腺研究会, Feb. 2019.
59.	Toru Sawada, Kazuya Kondo, Naoko Matsui, 鈴木恵美, 山田亮, Mika Takashima, Daisuke Matsumoto, Naoya Kawakita, Mitsuhiro Tsuboi, Hiroaki Toba, Mitsuteru Yoshida, Yukikiyo Kawakami, Hiromitsu Takizawa and Akira Tangoku : 当院におけるMGに対する拡大胸腺摘出術後の予後成績, 第38回日本胸腺研究会, Feb. 2019.
60.	副島志帆, 岸渕麗奈, 六車京香, Mitsuhiro Tsuboi, Koichiro Kajiura, Toru Sawada, Hiromitsu Takizawa and Kazuya Kondo : 胸腺上皮性腫瘍の悪性度と7つの遺伝子におけるDNAメチル化の関係, 第38回日本胸腺研究会, Feb. 2019.
61.	Hiromitsu Takizawa : 最良のがん治療に出会うために必要なこと, 徳島県民がんフォーラムがんとうまく付き合う患者術・生活術, Sep. 2018.
62.	Hiromitsu Takizawa : 徳島大学病院がん診療連携センターについて, 全人的医療を行う高度がん専門医療人養成第3回地域医療セミナー, Jul. 2018.
63.	青山万理子, Hiromitsu Takizawa, Mitsuhiro Tsuboi and Akira Tangoku : FDG-PET/CTで発見された甲状腺異常集積症例の検討, 第46回中国四国甲状腺外科研究会, Mar. 2018.
64.	Mitsuhiro Tsuboi, 青山万理子, Hiromitsu Takizawa, Takahiro Yoshida and Akira Tangoku : 気管食道狭窄を来した甲状腺原発悪性リンパ腫の1例, 第46回中国四国甲状腺外科研究会, Mar. 2018.
65.	Hiromitsu Takizawa : 治療の実際(肺癌，乳癌), 徳島大学大学院市民公開講座平成29年度中国・四国広域がんプロ養成コンソーシアム遺伝子診断(キャンサーパネル)により選ぶ新しいがん治療, Mar. 2018.
66.	Hiromitsu Takizawa : 肺癌の術前診断向上を目指した取り組み, 平成29年度徳島臨床細胞学会学術集会, Mar. 2018.
67.	Mitsuteru Yoshida, Kazuya Kondo, Toru Sawada, Naoya Kawakita, Mitsuhiro Tsuboi, Hiroaki Toba, Yukikiyo Kawakami, Hiromitsu Takizawa and Akira Tangoku : 組織診断に苦慮した前縦隔腫瘍の1切除例, 第37回日本胸腺研究会, Feb. 2018.
68.	Toru Sawada, Hiromitsu Takizawa, Naoya Kawakita, Mitsuhiro Tsuboi, Hiroaki Toba, Mitsuteru Yoshida, Yukikiyo Kawakami, Kazuya Kondo and Akira Tangoku : 肝細胞癌肺転移に対してICG蛍光観察下に胸腔鏡下肺部分切除術を行った1例, 第32回四国内視鏡外科研究会, Feb. 2018.
69.	Hiromitsu Takizawa : 進化するがん対策∼がん対策の歴史とこれから∼, 徳島県民がんフォーラム, Sep. 2017.
70.	Hiromitsu Takizawa : 進化するがん対策, 徳島ピンクリボン集会2017, Aug. 2017.
71.	青山万理子, Mitsuhiro Tsuboi, Hiromitsu Takizawa and Akira Tangoku : 橋本病によるステロイド抵抗性有痛性甲状腺炎の1例, 第45回中国四国甲状腺外科研究会, Feb. 2017.
72.	Mitsuhiro Tsuboi, 青山万理子, Hiromitsu Takizawa, 西岡康平, 藤本啓介, 宮本直輝, Naoya Kawakita and Akira Tangoku : レンバチニブ投与後に甲状腺全摘・気管合併切除を行った局所進行甲状腺乳頭癌の1例, 第45回中国四国甲状腺外科研究会, Feb. 2017.
73.	Wusiman Nuliamina, Kazuya Kondo, Koichiro Kajiura, Mitsuhiro Tsuboi, 岸渕麗奈, Hiroaki Toba, Naoya Kawakita, 澤田徹, Yukikiyo Kawakami, Mitsuteru Yoshida, Hiromitsu Takizawa and Akira Tangoku : 胸腺上皮性腫瘍におけるGAD1(glutamic acid decarboxylase 1)遺伝子プロモーター領域のDNAメチル化, 第36回日本胸腺研究会, Feb. 2017.
74.	Naoya Kawakita, Kazuya Kondo, Hiroaki Toba, Mitsuhiro Tsuboi, Koichiro Kajiura, Mitsuteru Yoshida and Hiromitsu Takizawa : 血管内発育と同時性肺転移を認めたA型胸腺腫の1例, 第36回日本胸腺研究会, Feb. 2017.
75.	乾友浩, 松本大資, 髙杉遥, 河北直也, Mitsuhiro Tsuboi, Koichiro Kajiura, Hiroaki Toba, Mitsuteru Yoshida, Yukikiyo Kawakami, Hiromitsu Takizawa, Kazuya Kondo, Shoji Sakiyama and Akira Tangoku : 術後乳糜胸により診断し得た縦隔内胸管嚢胞の1例, 第24回徳島外科術後管理研究会, Feb. 2016.
76.	Mitsuhiro Tsuboi, Hiromitsu Takizawa, 乾友浩, 髙杉遥, 松本大資, 河北直也 and Akira Tangoku : 総頸頚動脈再建を行った甲状腺乳頭癌の1例, 第44回中国四国甲状腺外科研究会, Jan. 2016.
77.	Hiromitsu Takizawa, Mitsuhiro Tsuboi, Hirokazu Takechi and Akira Tangoku : 多発リンパ節転移を伴った甲状腺髄様癌の1切除例, 第44回中国四国甲状腺外科研究会, Jan. 2016.
78.	行重佐和香, Hiroaki Toba, Yukikiyo Kawakami, Kazuya Kondo, 河北直也, Mitsuhiro Tsuboi, Koichiro Kajiura, Hiromitsu Takizawa, Shoji Sakiyama and Akira Tangoku : 肺犬糸状虫症の1切除例, 第251回徳島医学会学術集会, Aug. 2015.
79.	Hiromitsu Takizawa : 肺癌手術に関連した新しい可視化の取り組み, 3月度香川県内科医会呼吸器疾患談話会, Mar. 2015.
80.	Hiromitsu Takizawa : 肺癌手術に関連した新しい可視化の取り組み, 3月度香川県内科医会呼吸器疾患談話会, Mar. 2015.
81.	Hiromitsu Takizawa : 肺癌リンパ節転移診断の意義を考える, 第269回徳島呼吸器疾患談話会, Mar. 2015.
82.	Koichiro Kajiura, Shoji Sakiyama, Kazuya Kondo, 坂本晋一, 住友弘幸, Mitsuhiro Tsuboi, Hiroaki Toba, Yasushi Nakagawa, Yukikiyo Kawakami, Hiromitsu Takizawa and Akira Tangoku : Autofluorescence imaging(AFI)にて陰性所見を呈した中枢型早期扁平上皮癌の1症例, 第23回日本呼吸器内視鏡学会中国四国支部会, Feb. 2015.
83.	Mitsuhiro Tsuboi, Yasushi Nakagawa, Hiromitsu Takizawa, 坂本晋一, 住友弘幸 and Akira Tangoku : 当科における甲状腺乳頭癌リンパ節転移の検討, 第43回中国四国甲状腺外科研究会, Feb. 2015.
84.	Yasushi Nakagawa, 坂本晋一, 住友弘幸, Mitsuhiro Tsuboi, Hiromitsu Takizawa and Akira Tangoku : 甲状腺手術後出血症例の検討, 第43回中国四国甲状腺外科研究会, Feb. 2015.
85.	Koichiro Kajiura, Kazuya Kondo, 森本友樹, Mitsuhiro Tsuboi, Yasushi Nakagawa, Hiroaki Toba, Yukikiyo Kawakami, Hiromitsu Takizawa, Shoji Sakiyama and Akira Tangoku : 胸腺嚢胞と鑑別を要する腫瘍の大部分が嚢胞性変化を起こした胸腺腫の検討, 第34回日本胸腺研究会, Feb. 2015.
86.	Koichiro Kajiura, Kazuya Kondo, 森本友樹, Mitsuhiro Tsuboi, Yasushi Nakagawa, Hiroaki Toba, Yukikiyo Kawakami, Hiromitsu Takizawa, Shoji Sakiyama and Akira Tangoku : 胸腺癌におけるRASSF1遺伝子のDNAメチル化はB3胸腺腫よりも高い, 第34回日本胸腺研究会, Feb. 2015.
87.	住友弘幸, 西野豪志, Yoshihito Furukita, 坂本晋一, Takahiro Yoshida, Hirokazu Takechi, Jun-ichi Seike, Hiromitsu Takizawa and Akira Tangoku : バセドウ病に合併し，甲状腺亜全摘と食道憩室切除を同時に行ったkillian-Jamieson憩室症の1例, 第35回四国食道疾患研究会, Jan. 2015.
88.	Hiromitsu Takizawa : 周術期口腔機能管理と外科医との関わりについて, 徳島県歯科医師会・四国歯学会, Oct. 2014.
89.	森下敦司, Shoji Sakiyama, 西野豪志, Mitsuhiro Tsuboi, Koichiro Kajiura, Yasushi Nakagawa, Hiromitsu Takizawa, Yukikiyo Kawakami, Kazuya Kondo and Yoshimi Bando : Organizing blood clotを伴った後縦隔腫瘍の1例, 第28回四国内視鏡外科研究会, Feb. 2014.
90.	Mitsuhiro Tsuboi, 森下敦司, Koichiro Kajiura, Hiroaki Toba, Yasushi Nakagawa, Yukikiyo Kawakami, Hiromitsu Takizawa, Shoji Sakiyama, Kazuya Kondo and Akira Tangoku : 当院におけるPowered ECHELON FLEXTMの使用経験, 第28回四国内視鏡外科研究会, Feb. 2014.
91.	森下敦司, Kazuya Kondo, Naoko Matsui, Yoshimi Bando, Koichiro Kajiura, Hiromitsu Takizawa, Yasushi Nakagawa, Mitsuteru Yoshida, Yukikiyo Kawakami, Shoji Sakiyama and Akira Tangoku : 重症筋無力症を伴った胸腺のmultiple microcystsの一例, 第33回日本胸腺研究会, Feb. 2014.
92.	Yasushi Nakagawa, Kazuya Kondo, Mokhtar Mohamed, Ali Abdellah, 名村寿章, Koichiro Kajiura, 森本友樹, 高井チカ子, Hiromitsu Takizawa, Hiroaki Toba, Mitsuteru Yoshida, Yukikiyo Kawakami, Shoji Sakiyama and Akira Tangoku : 第33回日本胸腺研究会, 胸腺上皮性腫瘍におけるDNA修復遺伝子MGMTのメチル化と発現低下, Feb. 2014.
93.	Hiromitsu Takizawa : 肺癌手術の最近の話題, 第18回徳島大学病院がん診療連携セミナー, Jan. 2014.
94.	Hiromitsu Takizawa : 肺がん手術の最近の話題, 第17回徳島大学病院がん診療連携セミナー, Jul. 2013.
95.	Hiromitsu Takizawa, 池田真由美, 古川尊子, Koichiro Kajiura, Yasushi Nakagawa, Mitsuteru Yoshida, Yukikiyo Kawakami, Shoji Sakiyama, Kazuya Kondo and Akira Tangoku : ICG蛍光内視鏡を用いた胸腔鏡下区域切除域, 第11回スプリングセミナー IN OKINAWA, Mar. 2013.
96.	西野豪志, Shoji Sakiyama, 池田真由美, 森本雅美, 古川尊子, Koichiro Kajiura, Yukikiyo Kawakami, Mitsuteru Yoshida, Hiromitsu Takizawa, Yasushi Nakagawa, Kazuya Kondo and Akira Tangoku : 胸腔鏡手術を施行した月経随伴性気胸の2例, 第27回四国内視鏡外科研究会, Feb. 2013.
97.	高井ちか子, Yasushi Nakagawa, 大岩由香理, 藤田結衣, Hiromitsu Takizawa, Mitsuteru Yoshida, Yukikiyo Kawakami, Koichiro Kajiura, Shoji Sakiyama, Akira Tangoku, Yousuke Takahama and Kazuya Kondo : ヒト胸腺・胸腺腫における皮質・髄質componentのdistribution, 第32回日本胸腺研究会, Feb. 2013.
98.	Mitsuteru Yoshida, Kazuya Kondo, 横石道寛, Yasushi Nakagawa, Koichiro Kajiura, Hiroaki Toba, Yukikiyo Kawakami, Hiromitsu Takizawa, Shoji Sakiyama and Akira Tangoku : 症筋無力症患者の術前3D画像解析が拡大胸腺摘出術後の予後予測に及ぼす可能性, 第32回日本胸腺研究会, Feb. 2013.
99.	池田真由美, 西野豪志, Shoji Sakiyama, Koichiro Kajiura, Yasushi Nakagawa, Mitsuteru Yoshida, Yukikiyo Kawakami, Hiromitsu Takizawa, Kazuya Kondo and Akira Tangoku : 胸腺腫術後に両側横隔神経麻痺による呼吸不全をきたした1例, 第21回徳島外科術後管理研究会, Feb. 2013.
100.	宮本佳美, Yasushi Nakagawa, Hiromitsu Takizawa, 森本雅美, 後藤正和, Misako Nakagawa, Koichiro Kajiura, Yoshihito Furukita, Yota Yamamoto, Hirokazu Takechi, Yukikiyo Kawakami, Mitsuteru Yoshida, Koichiro Kenzaki and Akira Tangoku : 当科における頚部手術後出欠症例の検討, 第20回徳島外科術後管理研究会, Feb. 2012.
101.	Hiromitsu Takizawa : Ⅱ・Ⅲ期非小細胞肺癌患者に対するS-1術後補助化学療法完遂例の検討, 第46回徳島呼吸器外科研究会, Sep. 2011.
102.	Yukikiyo Kawakami, 梶浦耕一郎, 宇山攻, Hiroaki Toba, Yasushi Nakagawa, Hiromitsu Takizawa, Mitsuteru Yoshida, Koichiro Kenzaki, Shoji Sakiyama, Kazuya Kondo and Akira Tangoku : 肝細胞癌術後肺転移に対するICG蛍光法による腫瘍検出の試み, 第16回中国四国内視鏡外科研究会, Sep. 2011.
103.	梶浦耕一郎, Hiromitsu Takizawa, 高嶋美佳, 宇山攻, Hiroaki Toba, Yukikiyo Kawakami, Yasushi Nakagawa, Mitsuteru Yoshida, Koichiro Kenzaki, Shoji Sakiyama, Kazuya Kondo and Akira Tangoku : 多彩な陰影を呈した結節性リンパ組織過形成の3切除例, 第46回日本呼吸器学会中国・四国地方会第50回日本肺癌学会中国・四国支部会, Jul. 2011.
104.	Hiromitsu Takizawa : 最近の甲状腺疾患診療, 徳島病診連携座談会, May 2011.
105.	青山万理子, Yasushi Nakagawa, Hiromitsu Takizawa and Akira Tangoku : 甲状腺乳頭癌転移巣からBasedow病を来した1例, 第39回中国四国甲状腺外科研究会, Mar. 2011.
106.	兼松美幸, Hiromitsu Takizawa, Kazuya Kondo, 池田真由美, 三崎万理子, 高嶋美佳, 湊拓也, 梶浦耕一郎, 宇山攻, Hiroaki Toba, Misako Nakagawa, Yukikiyo Kawakami, Koichiro Kenzaki, Shoji Sakiyama and Akira Tangoku : 肺癌術後に肺動脈血栓塞栓症ならびにAcinetobacter baumannii敗血症を発症し，治療に難渋した1例, 第19回徳島外科術後管理研究会, Feb. 2011.
107.	名村寿章, Kazuya Kondo, Ali Hamed Khalil Abdellah, 藤田結衣, 岩佐裕介, 仙波義貴, 大岩由香理, 高井チカ子, Yasushi Nakagawa, Hiromitsu Takizawa, Hiroaki Toba, Yukikiyo Kawakami, Koichiro Kenzaki, Shoji Sakiyama and Akira Tangoku : 胸腺腫と胸腺癌におけるDNA修復遺伝子MGMT(O_6-methylguanine DNA methyltransferase)のメチル化, 第30回日本胸腺研究会, Feb. 2011.
108.	Hiroaki Toba, Shoji Sakiyama, 高田香, 高嶋美佳, 梶浦耕一郎, Hiromitsu Takizawa, Koichiro Kenzaki, Kazuya Kondo and Akira Tangoku : 摘出時にラリンジアルマスクが効果的であった小児気管支異物の1例, 第19回日本呼吸器内視鏡学会中国四国支部会, Jan. 2011.
109.	Hiromitsu Takizawa : 非小細胞肺癌完全切除症例に対する術後化学療法投与完遂性の検討, 第42回徳島呼吸器外科研究会, Sep. 2010.
110.	兼松美幸, Koichiro Kenzaki, Hiroaki Toba, Yasushi Nakagawa, Yukikiyo Kawakami, Hiromitsu Takizawa, Shoji Sakiyama, Kazuya Kondo and Akira Tangoku : 迷入性縦隔内甲状腺腫の一例, 第45回日本呼吸器学会中国・四国地方会第49回日本肺癌学会中国・四国支部会, Jul. 2010.
111.	Koichiro Kenzaki, Kazuya Kondo, Hiroaki Toba, Yasushi Nakagawa, Yukikiyo Kawakami, Hiromitsu Takizawa, Shoji Sakiyama and Akira Tangoku : 胸膜肺全摘術を施行した悪性胸膜中皮腫の臨床的検討, 第45回日本呼吸器学会中国・四国地方会第49回日本肺癌学会中国・四国支部会, Jul. 2010.
112.	高嶋美佳, Hiroaki Toba, Shoji Sakiyama, 藤原聡史, 兼松美幸, Yasushi Nakagawa, Hiromitsu Takizawa, Kazuya Kondo and Akira Tangoku : 縦隔リンパ節転移を有する胸腺異型カルチノイドに対して集学的治療を行った1例, 第53回関西胸部外科学会学術集会, Jun. 2010.

Grants-in-Aid for Scientific Research (KAKEN Grants Database @ NII.ac.jp)

網羅的なCpG siteのDNAメチル化の検索による肺腺癌のtumor suppressor geneの同定 (Project/Area Number: 23K08296 )
自家蛍光顕微鏡画像を用いた肺腺癌浸潤AI予測モデル構築と術中診断への応用 (Project/Area Number: 21K08905 )
The investigation of the cancer microenvironment using the orthotopic transplantation model of lung cancer (Project/Area Number: 19K09307 )
The attempt for lung regeneration using lung organid (lung cell and tissue transplantation) (Project/Area Number: 16K10685 )
Elucidating the mechanism of myasthenia gravis in B type thymoma with myasthenia gravis (Project/Area Number: 16K10684 )
Auto fluorescence findings of lung cancer specimens indicate invasiveness and prognosis (Project/Area Number: 16K10683 )
Fetal lung fragments implantation into fibrotic lung of a pig model (Project/Area Number: 26462127 )
Autofluorescence diagnosis of visceral pleural invasion and demonstration of the subpleural pathway of lymph node metastasis in patients with non-small cell lung cancer. (Project/Area Number: 25462178 )
System of measuring anti-cancer effect of orthotopic lung cancer transplantation mouse models using small animal PET/CT. (Project/Area Number: 24659634 )
Experimental examination of the pulmonary emphysema treatment with fetal lung tissues transplantation - a pig emphysema model - (Project/Area Number: 23592062 )
Computed tomography lymphography by transbronchial injection of iopamidol to identify sentinel nodes in preoperative non-small cell lung cancer patients (Project/Area Number: 22791312 )
The abnormality of some genes which repair DNA double strand break in lung cancer of the workers with chromate exposure. (Project/Area Number: 21591815 )
Fluorescence diagnosis of lung cancer and malignant mesothelioma using orthotopic ijplamtation SCID mice model (Project/Area Number: 20790991 )
Implantation of fetal pig lung fragments into adult rat lung parenchyma-search for a possibility of transbronchial delivery with a bronchoscope- (Project/Area Number: 20591672 )
Carcinogenesis mechanism of lung cancer of the chromate industrial workers with chromate exposure -Relationship between DNA mismatch repair hMLH gene and gene instability- (Project/Area Number: 18591551 )
ヒト乳癌のホルモン依存性喪失におけるマトリックスメトロプロテアーゼの意義 (Project/Area Number: 13770663 )
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Professor : Takizawa, Hiromitsu

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Grants-in-Aid for Scientific Research (KAKEN Grants Database @ NII.ac.jp)