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研究活動

専門分野

生殖内分泌

研究テーマ

著書・論文

著書:

1. 松崎 利也, 松井 寿美佳, 岩佐 武, 苛原 稔 :
月経不順と女性医療,
フジメディカル出版, 2014年11月.
2. 岩佐 武, 松崎 利也, 苛原 稔 :
体重減少性月経および神経性食欲不振症の診断と治療,
株式会社 中外医学社, 2014年7月.
3. 松崎 利也, 岩佐 武, 木内 理世, 藤澤 しのぶ, 苛原 稔 :
プロラクチン,
株式会社 診断と治療社, 2010年4月.

学術論文(審査論文):

1. Takeshi Iwasa, Toshiya Matsuzaki, Yiliyasi Mayila, Rie Yanagihara, Yuri Yamamoto, Takako Kawakita, Akira Kuwahara and Minoru Irahara :
Oxytocin treatment reduced food intake and body fat and ameliorated obesity in ovariectomized female rats.,
Neuropeptides, Vol.75, 49-57, 2019.
(DOI: 10.1016/j.npep.2019.03.002,   PubMed: 30885500)
2. Yuu Tanaka, Toshiya Matsuzaki, Naoko Tanaka, Takeshi Iwasa, Akira Kuwahara and Minoru Irahara :
Activin effects on follicular growth in in vitro preantral follicle culture.,
The Journal of Medical Investigation : JMI, Vol.66, No.1.2, 165-171, 2019.
(徳島大学機関リポジトリ: 113413,   DOI: 10.2152/jmi.66.165,   PubMed: 31064932)
3. Kaoru Keyama, Takeshi Katou, Yuri Kadota, Otgontsetseg Erdenebayar, Kana Kasai, Takako Kawakita, Anna Tani, Sumika Matsui, Takeshi Iwasa, Kanako Yoshida, Masahiko Maegawa, Akira Kuwahara, Toshiya Matsuzaki and Minoru Irahara :
Lipopolysaccharide promotes early endometrial-peritoneal interactions in a mouse model of endometriosis.,
The Journal of Medical Investigation : JMI, Vol.66, No.1.2, 70-74, 2019.
(徳島大学機関リポジトリ: 113324,   DOI: 10.2152/jmi.66.70,   PubMed: 31064958)
4. 岩佐 武, 谷口 友香, 中山 聡一朗, 米谷 直人, 吉田 あつ子, 阿部 彰子, 山本 由理, 加地 剛, 桑原 章, 松崎 利也, 苛原 稔 :
徳島大学病院産科婦人科における不育症患者に対する染色体検査の実施状況,
現代産婦人科, Vol.67, No.1, 21-24, 2018年.
5. Toshiya Matsuzaki, Munkhsaikhan Munkhzaya, Takeshi Iwasa, Altankhuu Tungalagsuvd, Kiyohito Yano, Yiliyasi Mayila, Rie Yanagihara, Takako Tokui, Takeshi Katou, Akira Kuwahara, Sumika Matsui and Minoru Irahara :
Prenatal undernutrition suppresses sexual behavior in female rats.,
General and Comparative Endocrinology, Vol.269, 46-52, 2018.
(DOI: 10.1016/j.ygcen.2018.08.013,   PubMed: 30099033)
6. Tomoko Yoshida, Toshiya Matsuzaki, Mami Miyado, Kazuki Saito, Takeshi Iwasa, Yoichi Matsubara, Tsutomu Ogata, Minoru Irahara and Maki Fukami :
11-oxygenated C19 steroids as circulating androgens in women with polycystic ovary syndrome.,
Endocrine Journal, Vol.65, No.10, 979-990, 2018.
(DOI: 10.1507/endocrj.EJ18-0212,   PubMed: 30012903)
7. Takeshi Iwasa, Toshiya Matsuzaki, Kiyohito Yano, Rie Yanagihara, Yiliyasi Mayila and Minoru Irahara :
The effects of chronic testosterone administration on hypothalamic gonadotropin-releasing hormone regulatory factors (Kiss1, NKB, pDyn and RFRP) and their receptors in female rats.,
Gynecological Endocrinology, Vol.34, No.5, 437-441, 2018.
(徳島大学機関リポジトリ: 112451,   DOI: 10.1080/09513590.2017.1409709,   PubMed: 29187003)
8. Toshiya Matsuzaki, Altankhuu Tungalagsuvd, Munkhsaikhan Munkhzaya, Takeshi Iwasa, Kiyohito Yano, Yiliyasi Mayila, Takako Tokui, Rie Yanagihara, Sumika Matsui, Takeshi Katou, Akira Kuwahara and Minoru Irahara :
Neurokinin B receptor agonist and Dynorphin receptor antagonist stimulated luteinizing hormone secretion in fasted male rodents.,
Endocrine Journal, Vol.65, No.4, 485-492, 2018.
(DOI: 10.1507/endocrj.EJ17-0136,   PubMed: 29479004)
9. Takeshi Iwasa, Toshiya Matsuzaki, Kiyohito Yano, Yiliyasi Mayila and Minoru Irahara :
Effects of dihydrotestosterone administration on the expression of reproductive and body weight regulatory factors in ovariectomized and estradiol-treated female rats.,
Gynecological Endocrinology, Vol.34, No.1, 73-77, 2018.
(徳島大学機関リポジトリ: 112455,   DOI: 10.1080/09513590.2017.1337096,   PubMed: 28604137)
10. Takeshi Iwasa, Toshiya Matsuzaki, Kiyohito Yano, Yiliyasi Mayila and Minoru Irahara :
The roles of kisspeptin and gonadotropin inhibitory hormone in stress-induced reproductive disorders.,
Endocrine Journal, Vol.65, No.2, 133-140, 2018.
(DOI: 10.1507/endocrj.EJ18-0026,   PubMed: 29375085)
11. Takeshi Iwasa, Toshiya Matsuzaki, Kiyohito Yano and Minoru Irahara :
The effects of ovariectomy and lifelong high-fat diet consumption on body weight, appetite, and lifespan in female rats.,
Hormones and Behavior, Vol.97, 25-30, 2017.
(徳島大学機関リポジトリ: 112452,   DOI: 10.1016/j.yhbeh.2017.10.005,   PubMed: 29054797)
12. Toshiya Matsuzaki, Munkhsaikhan Munkhzaya, Altankhuu Tungalagsuvd, Yiliyasi Mayila, Takeshi Iwasa, Kiyohito Yano, Rie Yanagihara, Takako Tokui, Takeshi Katou, Akira Kuwahara, Sumika Matsui and Minoru Irahara :
Prenatal undernutrition disrupted the sexual maturation, but not the sexual behavior, in male rats.,
Reproductive Medicine and Biology, Vol.16, No.4, 325-329, 2017.
(徳島大学機関リポジトリ: 112967,   DOI: 10.1002/rmb2.12045,   PubMed: 29259485)
13. Yuka Taniguchi, Akira Kuwahara, Ayaka Tachibana, Yuya Yano, Kiyohito Yano, Yuri Yamamoto, Mikio Yamasaki, Takeshi Iwasa, Kenji Hinokio, Toshiya Matsuzaki and Minoru Irahara :
Intra-follicular kisspeptin levels are related to oocyte maturation and gonadal hormones in patients who are undergoing assisted reproductive technology.,
Reproductive Medicine and Biology, Vol.16, No.4, 380-385, 2017.
(徳島大学機関リポジトリ: 112969,   DOI: 10.1002/rmb2.12056,   PubMed: 29259492)
14. Takeshi Iwasa, Toshiya Matsuzaki, Mayila Yiliyasi, Kiyohito Yano and Minoru Irahara :
The effects of chronic testosterone administration on body weight, food intake, and fat weight were age-dependent.,
Steroids, Vol.127, 18-23, 2017.
(徳島大学機関リポジトリ: 112453,   DOI: 10.1016/j.steroids.2017.08.014,   PubMed: 28893558)
15. Takeshi Iwasa, Toshiya Matsuzaki, Yiliyasi Mayila, Kiyohito Yano and Minoru Irahara :
Developmental changes in hypothalamic SF-1, POMC, and ERα mRNA expression and their sensitivity to fasting in male and female rats.,
Endocrine Journal, Vol.64, No.12, 1157-1163, 2017.
(DOI: 10.1507/endocrj.EJ17-0140,   PubMed: 28883210)
16. Mikio Yamasaki, Akira Kuwahara, Takeshi Iwasa, Yuri Yamamoto, Yuka Taniguchi, Yuya Yano, Sumika Matsui, Toshiya Matsuzaki and Minoru Irahara :
Development-related changes in the expression of the ovarian Kiss1 and Kiss1r genes and their sensitivity to human chorionic gonadotropin in prepubertal female rats.,
The Journal of Reproduction and Development, Vol.63, No.4, 409-414, 2017.
(徳島大学機関リポジトリ: 112975,   DOI: 10.1262/jrd.2016-179,   PubMed: 28552864)
17. Takeshi Iwasa, Toshiya Matsuzaki, Kiyohito Yano, Rie Yanagihara, Altankhuu Tungalagsuvd, Munkhsaikhan Munkhzaya, Yiliyasi Mayila, Akira Kuwahara and Minoru Irahara :
The effects of chronic testosterone administration on body weight, food intake, and adipose tissue are changed by estrogen treatment in female rats.,
Hormones and Behavior, Vol.93, 53-61, 2017.
(徳島大学機関リポジトリ: 112456,   DOI: 10.1016/j.yhbeh.2017.05.008,   PubMed: 28522306)
18. Minoru Irahara, Akira Kuwahara, Takeshi Iwasa, Tomonori Ishikawa, Osamu Ishihara, Koji Kugu, Rintaro Sawa, Kouji Banno and Hidekazu Saito :
Assisted reproductive technology in Japan: a summary report of 1992-2014 by the Ethics Committee, Japan Society of Obstetrics and Gynecology.,
Reproductive Medicine and Biology, Vol.16, No.2, 126-132, 2017.
(徳島大学機関リポジトリ: 112963,   DOI: 10.1002/rmb2.12014,   PubMed: 29259459)
19. Takeshi Iwasa, Toshiya Matsuzaki, Kiyohito Yano and Minoru Irahara :
Gonadotropin-Inhibitory Hormone Plays Roles in Stress-Induced Reproductive Dysfunction.,
Frontiers in Endocrinology, Vol.8, 62, 2017.
(徳島大学機関リポジトリ: 112957,   DOI: 10.3389/fendo.2017.00062,   PubMed: 28424661)
20. Toshiya Matsuzaki, Altankhuu Tungalagsuvd, Takeshi Iwasa, Munkhsaikhan Munkhzaya, Kiyohito Yano, Yiliyasi Mayila, Takako Tokui, Rie Yanagihara, Sumika Matsui, Takeshi Katou, Akira Kuwahara and Minoru Irahara :
Clinical outcome of various metformin treatments for women with polycystic ovary syndrome.,
Reproductive Medicine and Biology, Vol.16, No.2, 179-187, 2017.
(徳島大学機関リポジトリ: 112965,   DOI: 10.1002/rmb2.12026,   PubMed: 29259467)
21. Toshiya Matsuzaki, Munkhsaikhan Munkhzaya, Takeshi Iwasa, Altankhuu Tungalagsuvd, Kiyohito Yano, Yiliyasi Mayila, Rie Yanagihara, Takako Tokui, Takeshi Katou, Akira Kuwahara, Sumika Matsui and Minoru Irahara :
Relationship between serum anti-Mullerian hormone and clinical parameters in polycystic ovary syndrome.,
Endocrine Journal, Vol.64, No.5, 531-541, 2017.
(DOI: 10.1507/endocrj.EJ16-0501,   PubMed: 28381699)
22. Takeshi Iwasa, Toshiya Matsuzaki, Kiyohito Yano, Altankhuu Tungalagsuvd, Munkhsaikhan Munkhzaya, Yiliyasi Mayila, Akira Kuwahara and Minoru Irahara :
The effects of prenatal undernutrition and a high-fat postnatal diet on central and peripheral orexigenic and anorexigenic factors in female rats.,
Endocrine Journal, Vol.64, No.6, 597-604, 2017.
(DOI: 10.1507/endocrj.EJ16-0593,   PubMed: 28321032)
23. Toshiya Matsuzaki, Altankhuu Tungalagsuvd, Takeshi Iwasa, Munkhsaikhan Munkhzaya, Rie Yanagihara, Takako Tokui, Kiyohito Yano, Yiliyasi Mayila, Takeshi Katou, Akira Kuwahara, Sumika Matsui and Minoru Irahara :
Kisspeptin mRNA expression is increased in the posterior hypothalamus in the rat model of polycystic ovary syndrome.,
Endocrine Journal, Vol.64, No.1, 7-14, 2016.
(DOI: 10.1507/endocrj.EJ16-0282,   PubMed: 27665725)
24. Takeshi Iwasa, Toshiya Matsuzaki, Altankhuu Tungalagsuvd, Munkhsaikhan Munkhzaya, Maira Yiliyasi, Takeshi Katou, Akira Kuwahara and Minoru Irahara :
Developmental changes in the hypothalamic mRNA expression levels of PACAP and its receptor PAC1 and their sensitivity to fasting in male and female rats.,
International Journal of Developmental Neuroscience, Vol.52, 33-37, 2016.
(徳島大学機関リポジトリ: 112450,   DOI: 10.1016/j.ijdevneu.2016.05.003,   PubMed: 27181029)
25. Altankhuu Tungalagsuvd, Toshiya Matsuzaki, Takeshi Iwasa, Munkhsaikhan Munkhzaya, Mayila Yiliyasi, Takako Kawami, Takeshi Katou, Akira Kuwahara and Minoru Irahara :
The expression of orexigenic and anorexigenic factors in middle-aged female rats that had been subjected to prenatal undernutrition.,
International Journal of Developmental Neuroscience, Vol.49, 1-5, 2016.
(DOI: 10.1016/j.ijdevneu.2015.12.002,   PubMed: 26702900,   Elsevier: Scopus)
26. Kazuki Saito, Toshiya Matsuzaki, Takeshi Iwasa, Mami Miyado, Hidekazu Saito, Tomonobu Hasegawa, Keiko Homma, Eisuke Inoue, Yoshimichi Miyashiro, Toshiro Kubota, Minoru Irahara, Tsutomu Ogata and Maki Fukami :
Steroidogenic pathways involved in androgen biosynthesis in eumenorrheic women and patients with polycystic ovary syndrome.,
The Journal of Steroid Biochemistry and Molecular Biology, Vol.158, 31-37, 2016.
(DOI: 10.1016/j.jsbmb.2016.02.010,   PubMed: 26877255)
27. Takeshi Iwasa, Toshiya Matsuzaki, Altankhuu Tungalagsuvd, Munkhsaikhan Munkhzaya, Mayila Yiliyasi, Takeshi Katou, Akira Kuwahara and Minoru Irahara :
Prenatal undernutrition results in greater lipopolysaccharide-induced changes in hypothalamic TNF- expression, but does not affect the equivalent changes in the serum levels of luteinizing hormone and testosterone, in adult male rats.,
International Journal of Developmental Neuroscience, Vol.48, 80-83, 2016.
(DOI: 10.1016/j.ijdevneu.2015.12.001,   PubMed: 26674468)
28. Takeshi Iwasa, Toshiya Matsuzaki, Munkhsaikhan Munkhzaya, Altankhuu Tungalagsuvd, Mikio Yamasaki, Akira Kuwahara, Toshiyuki Yasui and Minoru Irahara :
The effects of prenatal undernutrition and postnatal high-fat diet on hypothalamic Kiss1 mRNA and serum leptin levels.,
International Journal of Developmental Neuroscience, Vol.42, 76-79, 2015.
(DOI: 10.1016/j.ijdevneu.2015.03.001,   PubMed: 25747502,   Elsevier: Scopus)
29. Toshiya Matsuzaki, Takeshi Iwasa, Munkhsaikhan Munkhzaya, Altankhuu Tungalagsuvd, Takako Kawami, Masahiro Murakami, Mikio Yamasaki, Yuri Yamamoto, Takeshi Kato, Akira Kuwahara, Toshiyuki Yasui and Minoru Irahara :
Developmental changes in hypothalamic oxytocin and oxytocin receptor mRNA expression and their sensitivity to fasting in male and female rats.,
International Journal of Developmental Neuroscience, Vol.41, 105-109, 2015.
(DOI: 10.1016/j.ijdevneu.2015.01.001,   PubMed: 25637830,   Elsevier: Scopus)
30. Toshiya Matsuzaki, Takeshi Iwasa, Altankhuu Tungalagsuvd, Munkhsaikhan Munkhzaya, Takako Kawami, Mikio Yamasaki, Masahiro Murakami, Takeshi Kato, Akira Kuwahara, Toshiyuki Yasui and Minoru Irahara :
The responses of hypothalamic NPY and OBRb mRNA expression to food deprivation develop during the neonatal-prepubertal period and exhibit gender differences in rats.,
International Journal of Developmental Neuroscience, Vol.41, 63-67, 2015.
(DOI: 10.1016/j.ijdevneu.2014.11.006,   PubMed: 25561025,   Elsevier: Scopus)
31. Takeshi Iwasa, Toshiya Matsuzaki, Sumika Matsui, Munkhsaikhan Munkhzaya, Altankhuu Tungalagsuvd, Takako Kawami, Masahiro Murakami, Takeshi Katou, Akira Kuwahara, Toshiyuki Yasui and Minoru Irahara :
The effects of LPS-induced endotoxemia on the expression of adiponectin and its receptors in female rats.,
Endocrine Journal, Vol.61, No.9, 891-900, 2014.
(DOI: 10.1507/endocrj.EJ14-0042,   PubMed: 24974879,   Elsevier: Scopus)
32. Hirobumi Niki, Toshiya Matsuzaki, Riyo Kinouchi, Takeshi Iwasa, Takako Kawami, Takeshi Katou, Akira Kuwahara and Minoru Irahara :
Improvement in diagnostic performance of the revised total testosterone measuring system in Japanese women with polycystic ovary syndrome.,
The Journal of Medical Investigation : JMI, Vol.61, No.1-2, 65-71, 2014.
(徳島大学機関リポジトリ: 109522,   DOI: 10.2152/jmi.61.65,   PubMed: 24705751,   Elsevier: Scopus)
33. M Murakami, E Takiguchi, S Hayashi, Y Nakagawa and Takeshi Iwasa :
Ovarian torsion associated with cessation of hormonal treatment for polycystic ovarian syndrome: a case report.,
Clinical and Experimental Obstetrics & Gynecology, Vol.40, No.4, 609-611, 2013.
(PubMed: 24597271,   Elsevier: Scopus)
34. Takeshi Iwasa, Toshiya Matsuzaki, Riyo Kinouchi, Ganbat Gereltsetseg, Masahiro Murakami, Akira Kuwahara, Toshiyuki Yasui and Minoru Irahara :
Developmental changes in the responsiveness of hypothalamic ER alpha mRNA levels to food deprivation.,
Neuroendocrinology Letters, Vol.34, No.6, 543-548, 2013.
(PubMed: 24378445)
35. Riyo Kinouchi, Toshiya Matsuzaki, Takeshi Iwasa, Ganbat Gereltsetseg, Hiroshi Nakazawa, Kotaro Kunimi, Akira Kuwahara, Toshiyuki Yasui and Minoru Irahara :
Prepubertal exposure to glucocorticoid delays puberty independent of the hypothalamic Kiss1-GnRH system in female rats.,
International Journal of Developmental Neuroscience, Vol.30, No.7, 596-601, 2012.
(DOI: 10.1016/j.ijdevneu.2012.09.001,   PubMed: 22982503)
36. Takeshi Iwasa, Toshiya Matsuzaki, Masahiro Murakami, Riyo Kinouchi, Tomohiro Osugi, Ganbat Gereltsetseg, Shinobu Yoshida, Minoru Irahara and Kazuyoshi Tsutsui :
Developmental changes in the mammalian gonadotropin-inhibitory hormone (GnIH) ortholog RFamide-related peptide (RFRP) and its cognate receptor GPR147 in the rat hypothalamus.,
International Journal of Developmental Neuroscience, Vol.30, No.1, 31-37, 2012.
(DOI: 10.1016/j.ijdevneu.2011.10.003,   PubMed: 22064075)
37. Toshiya Matsuzaki, Takeshi Iwasa, Riyo Kinouchi, Shinobu Yoshida, Masahiro Murakami, Ganbat Gereltsetseg, Satoshi Yamamoto, Akira Kuwahara, Toshiyuki Yasui and Minoru Irahara :
Fasting reduces the kiss1 mRNA levels in the caudal hypothalamus of gonadally intact adult female rats.,
Endocrine Journal, Vol.58, No.11, 1003-1012, 2011.
(DOI: 10.1507/endocrj.K11E-131,   PubMed: 21979277)
38. 中澤 浩志, 松崎 利也, 岩佐 武, 木内 理世, 苛原 稔 :
高プロラクチン血症として管理されていたマクロプロラクチン血症の2症例,
現代産婦人科, Vol.60, No.1, 179-184, 2011年.
(CiNii: 40019163532)
39. Takeshi Iwasa, Toshiya Matsuzaki, Riyo Kinouchi, Ganbat Gereltsetseg, Masahiro Murakami, Hiroshi Nakazawa, Shinobu Fujisawa, Satoshi Yamamoto, Akira Kuwahara, Toshiyuki Yasui and Minoru Irahara :
Effect of immune stress on body weight regulation is altered by ovariectomy in female rats.,
Journal of Reproductive Immunology, Vol.91, No.1-2, 41-47, 2011.
(DOI: 10.1016/j.jri.2011.05.010,   PubMed: 21855150)
40. Takeshi Iwasa, Toshiya Matsuzaki, Masahiro Murakami, Riyo Kinouchi, Ganbat Gereltsetseg, Hiroshi Nakazawa, Satoshi Yamamoto, Akira Kuwahara, Toshiyuki Yasui and Minoru Irahara :
Changes in responsiveness of appetite, leptin and hypothalamic IL-1β and TNF-α to lipopolysaccharide in developing rats.,
Journal of Neuroimmunology, Vol.236, No.1-2, 10-16, 2011.
(DOI: 10.1016/j.jneuroim.2011.04.004,   PubMed: 21621857)
41. 木内 理世, 松崎 利也, 岩佐 武, 三室 卓久, 苛原 稔 :
エクルーシス試薬テストステロンⅡ,LH,FSHの基準値の検討,
医学と薬学, Vol.64, No.1, 87-93, 2010年.
42. Masahiro Murakami, Takeshi Iwasa, Machiko Kiyokawa, Yohei Takahashi and Mikio Morine :
Investigation of the factors affecting the perinatal outcome of monochorionic diamniotic twins.,
Archives of Gynecology and Obstetrics, Vol.283, No.6, 1239-1243, 2010.
(DOI: 10.1007/s00404-010-1549-3,   PubMed: 20549508)
43. Takeshi Iwasa, Toshiya Matsuzaki, Riyo Kinouchi, Shinobu Fujisawa, Masahiro Murakami, Machiko Kiyokawa, Akira Kuwahara, Toshiyuki Yasui and Minoru Irahara :
Neonatal LPS injection alters the body weight regulation systems of rats under non-stress and immune stress conditions.,
International Journal of Developmental Neuroscience, Vol.28, No.1, 119-124, 2010.
(DOI: 10.1016/j.ijdevneu.2009.08.015,   PubMed: 19733650)
44. Takeshi Iwasa, Toshiya Matsuzaki, Masahiro Murakami, Shinobu Fujisawa, Riyo Kinouchi, Ganbat Gereltsetseg, Akira Kuwahara, Toshiyuki Yasui and Minoru Irahara :
Effects of intrauterine undernutrition on hypothalamic Kiss1 expression and the timing of puberty in female rats.,
The Journal of Physiology, Vol.588, No.Pt 5, 821-829, 2010.
(DOI: 10.1113/jphysiol.2009.183558,   PubMed: 20083512)
45. Masahiro Murakami, Hisanori Uehara, Masato Nishimura, Takeshi Iwasa and Hiroshi Ikawa :
A huge ovarian smooth muscle tumor: a case report.,
The Journal of Medical Investigation : JMI, Vol.57, No.1-2, 158-162, 2010.
(徳島大学機関リポジトリ: 67872,   DOI: 10.2152/jmi.57.158,   PubMed: 20299756)
46. Rie Ogata, Toshiya Matsuzaki, Takeshi Iwasa, Machiko Kiyokawa, Naoko Tanaka, Akira Kuwahara, Toshiyuki Yasui and Minoru Irahara :
Hypothalamic Ghrelin suppresses pulsatile secretion of luteinizing hormone via beta-endorphin in ovariectomized rats.,
Neuroendocrinology, Vol.90, No.4, 364-370, 2009.
(DOI: 10.1159/000257421,   PubMed: 19907132)
47. Takeshi Iwasa, Toshiya Matsuzaki, Masahiro Murakami, Fumi Shimizu, Akira Kuwahara, Toshiyuki Yasui and Minoru Irahara :
Reproducibility of luteinizing hormone hypersecretion in different phases of the menstrual cycle in polycystic ovary syndrome.,
The Journal of Obstetrics and Gynaecology Research, Vol.35, No.3, 514-519, 2009.
(DOI: 10.1111/j.1447-0756.2008.00998.x,   PubMed: 19527392,   CiNii: 10025340283)
48. Takeshi Iwasa, Toshiya Matsuzaki, Masahiro Murakami, Riyo Kinouchi, Rie Ogata, Akira Kuwahara, Toshiyuki Yasui and Minoru Irahara :
Neonatal lipopolysaccharide exposure attenuates the homotypic stress-induced suppression of LH secretion in adulthood in male rat.,
International Journal of Developmental Neuroscience, Vol.27, No.4, 345-349, 2009.
(DOI: 10.1016/j.ijdevneu.2009.03.004,   PubMed: 19460628)
49. Takeshi Iwasa, Anna Tani, Yuka Miyatani, Shirou Bekku, Michiko Yamashita, Kazuyo Nakanishi, Yoshiyuki Fujii and Hiroyasu Ino :
Lymphangioma of the ovary accompanied by chylous ascites.,
The Journal of Obstetrics and Gynaecology Research, Vol.35, No.4, 812-815, 2009.
(DOI: 10.1111/j.1447-0756.2009.01016.x,   PubMed: 19751350,   CiNii: 10025341437,   Elsevier: Scopus)
50. Takeshi Iwasa, Toshiya Matsuzaki, Masahiro Murakami, Riyo Kinouchi, Fumi Shimizu, Akira Kuwahara, Toshiyuki Yasui and Minoru Irahara :
Neonatal immune challenge affects the regulation of estrus cyclicity and feeding behavior in female rats.,
International Journal of Developmental Neuroscience, Vol.27, No.1, 111-114, 2008.
(DOI: 10.1016/j.ijdevneu.2008.10.003,   PubMed: 18996180)
51. Masahiro Murakami, Toshiya Matsuzaki, Takeshi Iwasa, Toshiyuki Yasui, Minoru Irahara, Tomohiro Osugi and Kazuyoshi Tsutsui :
Hypophysiotropic role of RFamide-related peptide-3 in the inhibition of LH secretion in female rats.,
The Journal of Endocrinology, Vol.199, No.1, 105-112, 2008.
(DOI: 10.1677/JOE-08-0197,   PubMed: 18653621)
52. Fumi Shimizu, Toshiya Matsuzaki, Takeshi Iwasa, Naoko Tanaka, Masahiro Minakuchi, Akira Kuwahara, Toshiyuki Yasui, Hiroyuki Furumoto and Minoru Irahara :
Transition of leptin receptor expression during pubertal development in female rat pituitary.,
Endocrine Journal, Vol.55, No.1, 191-198, 2008.
(DOI: 10.1507/endocrj.K07E-029,   PubMed: 18250539)
53. Takeshi Iwasa, Toshiya Matsuzaki, Masahiro Murakami, Fumi Shimizu, Akira Kuwahara, Toshiyuki Yasui and Minoru Irahara :
Decreased expression of kisspeptin mediates acute immune/inflammatory stress-induced suppression of gonadotropin secretion in female rat.,
Journal of Endocrinological Investigation, Vol.31, No.7, 656-659, 2008.
(PubMed: 18787387)
54. Fumi Shimizu, Toshiya Matsuzaki, Takeshi Iwasa, Masahiro Minakuchi, Akira Kuwahara, Toshiyuki Yasui and Minoru Irahara :
Estradiol suppresses NMU mRNA expression during sexual maturation in the female rat pituitary.,
International Journal of Developmental Neuroscience, Vol.26, No.3-4, 381-384, 2007.
(DOI: 10.1016/j.ijdevneu.2007.11.002,   PubMed: 18258403)
55. Takeshi Iwasa, Toshiya Matsuzaki, Masahiro Minakuchi, Naoko Tanaka, Fumi Shimizu, Yohko Hirata, Akira Kuwahara, Toshiyuki Yasui, Masahiko Maegawa and Minoru Irahara :
Diagnostic performance of serum total testosterone for Japanese patients with polycystic ovary syndrome.,
Endocrine Journal, Vol.54, No.2, 233-238, 2007.
(DOI: 10.1507/endocrj.K06-159,   PubMed: 17283381)
56. Takeshi Iwasa, Toshiya Matsuzaki, Machiko Kiyokawa, Fumi Shimizu, Masahiro Minakuchi, Akira Kuwahara, Masahiko Maegawa, Toshiyuki Yasui and Minoru Irahara :
The type 2 corticotrophin-releasing hormone receptor mediates orexin A-induced luteinising hormone suppression in ovariectomised rats.,
Journal of Neuroendocrinology, Vol.19, No.9, 732-738, 2007.
(DOI: 10.1111/j.1365-2826.2007.01583.x,   PubMed: 17680889)
57. Takeshi Iwasa, Toshiya Matsuzaki, Naoko Tanaka, Masahiro Minakuchi, Fumi Shimizu, Rie Ogata, Machiko Kiyokawa, Masahiko Maegawa, Toshiyuki Yasui, Akira Kuwahara and Minoru Irahara :
Comparison and problems of measured values of LH, FSH, and PRL among measurement systems.,
Endocrine Journal, Vol.53, No.1, 101-109, 2006.
(DOI: 10.1507/endocrj.53.101,   PubMed: 16543679,   Elsevier: Scopus)

学術論文(紀要・その他):

1. 矢野 清人, 松崎 利也, 柳原 里江, 岩佐 武, 苛原 稔 :
産婦人科外来パーフェクトガイド : いまのトレンドを逃さずチェック!, --- 思春期・月経異常 視床下部・下垂体性無月経. ---,
臨床婦人科産科, Vol.72, No.4, 64-68, 2018年.
(CiNii: 40021554059)

総説・解説:

1. 岩佐 武, 松崎 利也, 苛原 稔 :
卵巣機能とストレス反応,
Hormone Frontier in Gynecology, Vol.21, No.4, 21-25,
2. Takeshi Iwasa, Toshiya Matsuzaki, Kiyohito Yano, Yiliyasi Mayila, Rie Yanagihara, Yuri Yamamoto, Akira Kuwahara and Minoru Irahara :
Effects of Low Energy Availability on Reproductive Functions and Their Underlying Neuroendocrine Mechanisms.,
Journal of Clinical Medicine, Vol.7, No.7, Jul. 2018.
(DOI: 10.3390/jcm7070166,   PubMed: 29976877)
3. 岩佐 武, 松崎 利也, 矢野 清人, 苛原 稔 :
産婦人科画像診断トレーニング:多嚢胞性卵巣症候群の画像診断とその臨床的意義は?,
臨床婦人科産科, Vol.71, No.4, 199-202, 2017年4月.
4. 岩佐 武, 松崎 利也, 苛原 稔 :
中枢性月経異常,
臨床婦人科産科, Vol.70, No.6, 481-485, 2016年6月.
5. 松崎 利也, 岩佐 武, 苛原 稔 :
アディポサイトカインとゴナドトロピン分泌,
HORMONE FRONTIER IN GYNRCOLOGY, Vol.21, No.3, 31-37, 2014年9月.
6. 松崎 利也, 岩佐 武, 苛原 稔 :
新たに開発されたアーキテクト・テストステロンⅡの性能評価と多囊胞性卵巣症候群(PCOS)の診断における有用性の検討,
医学と薬学, Vol.70, No.20, 331-339, 2013年8月.
7. 松崎 利也, 岩佐 武, 木内 理世, 苛原 稔 :
新しい排卵誘発法,
産婦人科治療, Vol.102, No.102, 753-760, 2011年5月.
(CiNii: 40018836381)
8. 松崎 利也, 岩佐 武, 木内 理世, 苛原 稔 :
多嚢胞性卵巣症候群,
産科と婦人科, Vol.77, No.11, 1325-1333, 2010年11月.
(CiNii: 40017353011)
9. 岩佐 武, 松崎 利也, 苛原 稔 :
ストレス・摂食調節因子によるゴナドトロピン分泌制御 (今月の臨床 ここが問題 若年女性のやせ・肥満),
臨床婦人科産科, Vol.64, No.9, 1293-1299, 2010年9月.
(CiNii: 40017268353)
10. 苛原 稔, 松崎 利也, 岩佐 武, 桑原 章 :
不妊治療と多嚢胞性卵巣症候群 (特集 妊孕能の可能性と限界を考える),
産婦人科の実際, Vol.59, No.5, 705-710, 2010年5月.
(CiNii: 40017137496)
11. 岩佐 武, 松崎 利也, 苛原 稔 :
摂食とストレスによる生殖機能調節への影響 (特集 生殖機能調節の新しい視点),
産科と婦人科, Vol.77, No.3, 265-272, 2010年3月.
(CiNii: 40017005896)
12. 岩佐 武, 松崎 利也, 木内 理世 :
思春期から妊娠前 (特集 肥満およびやせ女性における栄養代謝学的問題点と対策) -- (肥満女性の栄養代謝学的問題点とその管理),
産婦人科の実際, Vol.57, No.8, 1211-1217, 2008年8月.
(CiNii: 40016194751)
13. 岩佐 武, 松崎 利也, 水口 雅博 :
薬剤の臨床 ARCHITECTアナライザーi2000を用いた血中エストラジオール,プロゲステロンおよびテストステロン測定の臨床的検討,
産科と婦人科, Vol.73, No.1, 133-140, 2006年1月.

国際会議:

1. YAMASAKI Mikio, Akira Kuwahara, TANIGUCHI Yuka, Yuri Yamamoto, Takeshi Iwasa, HINOKIO Kenji, Toshiya Matsuzaki and Minoru Irahara :
Comparison of AMH and FSH an indicator of ovarian reserve in ART.,
IFFS/JSRM International Meeting,2015, Yokohama, Apr. 2015.
2. Akira Kuwahara, HINOKIO Kenji, TANIGUCHI Yuka, Yuri Yamamoto, YAMASAKI Mikio, Takeshi Iwasa and Minoru Irahara :
Clinical significance of estradiol and transvaginal ultrasonography for pregnancy outcomes in natural frozen-thawed blastcyst transfer cycles.,
IFFS/JSRM International Meeting,2015, Yokohama, Apr. 2015.
3. Takeshi Iwasa, Toshiya Matsuzaki, KAWAMI Takako, MUNKHZAYA Mukhsaikhan, TUNGALAGSUVD Altankhuu and Minoru Irahara :
Hypothalamic Kiss1 and RFRP gene expressions are changed by a high dose of lipopolysaccharide in female rats.,
IFFS/JSRM International Meeting 2015, Yokohama, Apr. 2015.
4. TUNGALAGSUVD Altankhuu, Toshiya Matsuzaki, Takeshi Iwasa, MUNKHZAYA Munkhsaikhan, KAWAMI Takako and Minoru Irahara :
Senktide does not recover suppression of HPG axis induced by acute fasting in male rats.,
IFFS/JSRM International Meeting,2015, Yokohama, Apr. 2015.
5. MUNKHZAYA Munkhsaikhan, Toshiya Matsuzaki, Takeshi Iwasa, TUNGALAGSUVD Altankhuu, KAWAMI Takako and Minoru Irahara :
Suppressive effect of immune stress on LH secretion is absent in early neonatal period in rats.,
IFFS/JSRM International Meeting,2015, Yokohama, Apr. 2015.
6. Akiko Abe, Masato Nishimura, Eri Takiguchi, Takako Kawakita, TANIGUCHI Yuka, Yuri Yamamoto, YAMASAKI Mikio, Takeshi Iwasa, Akira Kuwahara, Toshiya Matsuzaki and Minoru Irahara :
Survey on oncologist and gynecologist concerned with fertility for cancer survivors in reproductive age.,
IFFS/JSRM International Meeting,2015, Yokohama, Apr. 2015.
7. Masato Nishimura, Eri Takiguchi, Takako Kawakita, Akiko Abe, TANIGUCHI Yuka, Yuri Yamamoto, YAMASAKI Mikio, Takeshi Iwasa, Akira Kuwahara, Toshiya Matsuzaki and Minoru Irahara :
Efficacy and pregnant outcomes of fertility-sparing treatment with medroxyprogesterone acetate for endometrial carcinoma and atypical endometrial hyperplasia in young women.,
IFFS/JSRM International Meeting,2015, Yokohama, Apr. 2015.
8. Nakazawa Hiroshi, Toshiya Matsuzaki, Takeshi Iwasa, Kinouchi Riyo, Gereltsetseg Ganbat and Minoru Irahara :
Early Postnatal Lipopolysaccharide Exposure : Effects on Adult Male Rat LH Response to Homotypic Stress.,
The Endocrine Society's 94th Annual Meeting & Expo, Houston, Jun. 2012.
9. Gereltsetseg Ganbat, Toshiya Matsuzaki, Takeshi Iwasa, Kinouchi Riyo, Nakazawa Hiroshi and Minoru Irahara :
Delay in the Onset of Puberty of Intrauterine Growth Retarded Female Rats Cannot Be Rescued with Hypernutrition after Birth.,
The Endocrine Society's 94th Annual Meeting & Expo, Houston, Jun. 2012.
10. Toshiya Matsuzaki, Gereltsetseg Ganbat, Takeshi Iwasa, Kinouchi Riyo, Nakazawa Hiroshi and Minoru Irahara :
Delay in the onset of puberty of intrauterine growth retarded female rats cannot be rescued by hypernutrition after birth.,
15th International & 14th European Congress of Endocrinology(ICE/ECE 2012), Florence, May 2012.
11. Takeshi Iwasa, Toshiya Matsuzaki, Shinobu Fujisawa, Riyo Kinouchi, Gereltsetseg Ganbat and Minoru Irahara :
Effects of Intra-Uterine Undernutrition on Hypothalamic Kiss1 Expression and the Timing of Puberty in Female Rats.,
The Endocrine Society's 92nd Annual Meeting, San Diego,CA,USA., Jun. 2010.
12. K Tsutsui, VS Chowdhury, T Osugi, T Ubuka, Toshiya Matsuzaki, Takeshi Iwasa, Minoru Irahara, LJ Kriegsfeld and G Bentley :
Discovery of GnIH: first in birds and then in mammals Symposium: Gonadotropin inhibitory hormone (GnIH) functions in mammals.,
The Endocrine Society's 92nd Annual Meeting, San Diego,CA,USA., Jun. 2010.
13. Toshiya Matsuzaki, Takeshi Iwasa, Shinobu Fujisawa, Riyo Kinouchi and Minoru Irahara :
Neonatal LPS Injection Alters the Body Weight Regulation Systems of Rats under Non-Stress and Immune Stress Conditions.,
The Endocrine Society's 92nd Annual Meeting, San Diego, CA ,USA., Jun. 2010.

国内講演発表:

1. 岩佐 武 :
シンポジウム: ストレスによる生殖機能低下におけるGonadotropin inhibitory hormone(GnIH)の意義,
第20回日本生殖内分泌学会学術集会, 2016年1月.
2. 岩佐 武 :
リサーチアップデート:kisspeptinおよびGnIHによるGnRH分泌調節機構,
第67回中国四国産科婦人科学会総会ならびに学術講演会, 2014年9月.
3. 岩佐 武 :
ミニワークショップ: 卵巣摘出が中枢·末梢のストレス反応に及ぼす影響,
第66回日本産科婦人科学会学術講演会, 2014年4月.
4. 岩佐 武, 松崎 利也, 苛原 稔 :
シンポジウム: GnIH,キスペプチン/メタスチンによる性腺機能調節, --- 胎生期の低栄養がキスペプチン/メタスチンに及ぼす影響 ---,
第85回日本内分泌学会学術総会, 2012年4月.

科学研究費補助金 (KAKEN Grants Database @ NII.ac.jp)

  • 多嚢胞性卵巣症候群の血中性腺ホルモンとAMHを用いた診断精度の向上に関する研究 (研究課題/領域番号: 18K09293 )
  • 胎生期の低栄養と出生後の栄養環境が生殖機能に及ぼす長期的影響とその機序の解明 (研究課題/領域番号: 18K09292 )
  • 出生後早期に受けた各種ストレスが成長後の性機能に及ぼす長期的影響に関する研究 (研究課題/領域番号: 18K09264 )
  • 視床下部機能低下時の新規中枢神経ペプチドアナログによる新しい排卵誘発法の基礎検討 (研究課題/領域番号: 15K10673 )
  • 多嚢胞性卵巣症候群の診断基準におけるAMHとインスリン抵抗性の意義に関する研究 (研究課題/領域番号: 15K10672 )
  • 卵巣機能の低下が中枢・末梢のストレス反応に及ぼす影響とその機序の検討 (研究課題/領域番号: 26462526 )
  • 研究者番号(00707903)による検索